Package: RVS
Type: Package
Title: Computes estimates of the probability of related individuals
        sharing a rare variant
Version: 1.35.0
Date: 2024-02-14
Author: Alexandre Bureau, Ingo Ruczinski, Samuel Younkin, Thomas
        Sherman
Maintainer: Alexandre Bureau <alexandre.bureau@fmed.ulaval.ca>
Description: Rare Variant Sharing (RVS) implements tests of association
        and linkage between rare genetic variant genotypes and a
        dichotomous phenotype, e.g. a disease status, in family
        samples. The tests are based on probabilities of rare variant
        sharing by relatives under the null hypothesis of absence of
        linkage and association between the rare variants and the
        phenotype and apply to single variants or multiple variants in
        a region (e.g. gene-based test).
License: GPL-2
Depends: R (>= 3.5.0)
Imports: GENLIB, gRain, snpStats, kinship2, methods, stats, utils,
        R.utils
Suggests: knitr, testthat, rmarkdown, BiocStyle, VariantAnnotation
VignetteBuilder: knitr
LazyData: true
RoxygenNote: 7.1.0
Encoding: UTF-8
biocViews: ImmunoOncology, Genetics, GenomeWideAssociation,
        VariantDetection, ExomeSeq, WholeGenome
Collate: 'RVgene.R' 'pedigree-methods.R' 'RVsharing.R'
        'documentation.R' 'grainNetworkHelper.R' 'monteCarloMethods.R'
        'multipleFamilyCalculations.R'
        'multipleFamilyCalculationsBackend.R'
        'relatedFoundersCorrection.R'
        'sharingProbabilityCalculations.R'
        'sharingProbabilityCalculationsSplitting.R'
Config/pak/sysreqs: libglpk-dev libicu-dev libxml2-dev zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:46:08 UTC
RemoteUrl: https://github.com/bioc/RVS
RemoteRef: HEAD
RemoteSha: 91844438b1a0e5ef5a2631ad5b28229bef2d0325
NeedsCompilation: no
Packaged: 2026-07-03 20:23:54 UTC; root