# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "RNAsense" in publications use:' type: software license: GPL-3.0-only title: 'RNAsense: Analysis of Time-Resolved RNA-Seq Data' version: 1.19.0 abstract: RNA-sense tool compares RNA-seq time curves in two experimental conditions, i.e. wild-type and mutant, and works in three steps. At Step 1, it builds expression profile for each transcript in one condition (i.e. wild-type) and tests if the transcript abundance grows or decays significantly. Dynamic transcripts are then sorted to non-overlapping groups (time profiles) by the time point of switch up or down. At Step 2, RNA-sense outputs the groups of differentially expressed transcripts, which are up- or downregulated in the mutant compared to the wild-type at each time point. At Step 3, Correlations (Fisher's exact test) between the outputs of Step 1 (switch up- and switch down- time profile groups) and the outputs of Step2 (differentially expressed transcript groups) are calculated. The results of the correlation analysis are printed as two-dimensional color plot, with time profiles and differential expression groups at y- and x-axis, respectively, and facilitates the biological interpretation of the data. authors: - family-names: Rosenblatt given-names: Marcus email: marcus.rosenblatt@gmail.com - family-names: Meijang given-names: Gao - family-names: Hass given-names: Helge - family-names: Onichtchouk given-names: Daria repository: https://bioc.r-universe.dev repository-code: https://github.com/marcusrosenblatt/RNAsense url: https://github.com/marcusrosenblatt/RNAsense contact: - family-names: Rosenblatt given-names: Marcus email: marcus.rosenblatt@gmail.com