Changes in version 0.99.0                        

New Features

  - Initial Bioconductor submission
  - Inherent Specificity (IS) calculation from k-mer enrichment data
  - Variation Sensitivity (VS) quantification for motif variants
  - De novo enrichment from CLIP peak data via motifEnrichment()

Core Functions

  - returnIS() - Calculate Inherent Specificity for motifs
  - returnVS() - Calculate Variation Sensitivity matrices or scores
  - motifEnrichment() - Generate k-mer enrichment from peak data

Visualization

  - plotIS() - Score distribution histograms with IS annotation
  - plotVS() - Variation sensitivity profile visualization

Data Support

  - RBNS enrichment data input
  - eCLIP/iCLIP peak data processing
  - Multiple genome support (hg38, mm10, etc.)

Future Implementations

  - PWM exploration