NEWS

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RBPSpecificity 0.99.0

New Features

• Initial Bioconductor submission
• Inherent Specificity (IS) calculation from k-mer enrichment data
• Variation Sensitivity (VS) quantification for motif variants
• De novo enrichment from CLIP peak data via motifEnrichment()

Core Functions

• returnIS() - Calculate Inherent Specificity for motifs
• returnVS() - Calculate Variation Sensitivity matrices or scores
• motifEnrichment() - Generate k-mer enrichment from peak data

Visualization

• plotIS() - Score distribution histograms with IS annotation
• plotVS() - Variation sensitivity profile visualization

Data Support

• RBNS enrichment data input
• eCLIP/iCLIP peak data processing
• Multiple genome support (hg38, mm10, etc.)

Future Implementations

• PWM exploration