Package: PscanR Type: Package Title: Motif Enrichment Analysis of Regulatory DNA Sequences Version: 0.99.4 Encoding: UTF-8 Depends: R (>= 4.5.0) Imports: BiocFileCache, BiocParallel, BiocGenerics, Biostrings, ExperimentHub, ggplot2, grDevices, methods, pheatmap, RSQLite, stats, TFBSTools, UCSC.utils, utils Suggests: AnnotationDbi, BiocStyle, BSgenome, BSgenome.Athaliana.TAIR.TAIR9, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, BSgenome.Scerevisiae.UCSC.sacCer3, GenomicFeatures, GenomicRanges, GenomeInfoDb, IRanges, JASPAR2020, JASPAR2022, JASPAR2024, knitr, org.Hs.eg.db, org.Mm.eg.db, org.Sc.sgd.db, PscanRBackgrounds, rmarkdown, testthat, TxDb.Scerevisiae.UCSC.sacCer3.sgdGene, txdbmaker biocViews: SequenceMatching, Transcription, GeneRegulation, MotifAnnotation Authors@R: c(person("Federico", "Zambelli", email = "federico.zambelli@unimi.it", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-3487-4331")), person("Giulio", "Pavesi", email = "giulio.pavesi@unimi.it", role = "aut", comment = c(ORCID = "0000-0001-5705-6249")), person("Diana", "Betelli", role = "ctb"), person("Italy's National Recovery and Resilience Plan (PNRR)", role = "fnd", comment = "project ELIXIRNextGenIT, R0000010")) Description: R implementation of the 'Pscan' algorithm for motif enrichment analysis in regulatory DNA sequences, based on Zambelli et al. (2009) . 'PscanR' scans a set of DNA sequences (e.g., promoters) from co-regulated or co-expressed genes, using transcription factor binding motifs from databases such as JASPAR. It identifies significantly enriched motifs, providing thus hints on which transcription factors could be common regulators of the genes studied, together with the location of their candidate binding sites in the sequences. License: GPL-3 VignetteBuilder: knitr URL: https://github.com/Federico77z/PscanR BugReports: https://github.com/Federico77z/PscanR/issues Config/testthat/edition: 3 Config/roxygen2/version: 8.0.0 Config/pak/sysreqs: make libgsl0-dev libbz2-dev libicu-dev liblzma-dev libpng-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-11-11 13:29:05 UTC RemoteUrl: https://github.com/bioc/PscanR RemoteRef: HEAD RemoteSha: be6299a2f0d99fc71faa7e4d58161b7851cdd53c NeedsCompilation: no Packaged: 2026-11-11 22:18:20 UTC; root Author: Federico Zambelli [aut, cre] (ORCID: ), Giulio Pavesi [aut] (ORCID: ), Diana Betelli [ctb], Italy's National Recovery and Resilience Plan (PNRR) [fnd] (project ELIXIRNextGenIT, R0000010) Maintainer: Federico Zambelli