Package: ProteinBatcher Title: An end-to-end proteomics workflow with condition-aware imputation, flexible statistical modelling and interactive visualization Version: 0.99.7 Authors@R: c(person(given = "Aitor", family ="Moruno-Cuenca", email = "morunoaitor@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0009-0009-8133-2552")), person(given = "Dr. Sergi", family = "Sayols-Puig", email = "sergi.sayolspuig@almirall.com", role = c("ctb"), comment = c(ORCID = "0000-0002-3877-4170")), person(given = "Dr. Bruna", family = "Oriol-Tordera", email = "bruna.orioltordera@almirall.com", role = c("ctb"), comment = c(ORCID = "0000-0002-2714-9097")), person(given = "Dr. Hiba", family = "Salim", email = "hiba.salim@crg.eu", role = c("dtc"), comment = c(ORCID = "0000-0002-2168-0258")), person(given = "Dr. Francesc", family = "Fernández-Albert", email = "francesc.fernandez@almirall.com", role = c("ths"), comment = c(ORCID = "0000-0001-5561-0701")), person(given = "Prof. Dr. Alexandre", family = "Perera-Lluna", email = "alexandre.perera@upc.edu", role = c("ths"), comment = c(ORCID = "0000-0001-6427-851X")), person(given = "Dr. Guadalupe", family = "Espadas-García", email = "guadalupe.espadas@crg.eu", role = c("ctb", "dtc"), comment = c(ORCID = "0000-0002-6415-8013")), person(given = "Dr. Elisa", family = "Monzón-Casanova", email = "elisa.monzoncasanova@almirall.com", role = c("ctb", "fnd"), comment = c(ORCID = "0000-0001-6617-6138")), person(given = "Prof. Dr. Eduard", family = "Sabidó-Aguade", email = "eduard.sabido@upf.edu", role = c("res", "ctb", "dtc", "fnd"), comment = c(ORCID = "0000-0001-6506-7714"))) Description: ProteinBatcher provides utilities to read, validate, and harmonize quantitative proteomics result tables generated by DIA-NN from data-independent acquisition mass spectrometry experiments. The package enables batch processing of multiple DIA-NN output files, consistent handling of protein identifiers and associated metadata, and transformation of tabular data into analysis-ready formats. It facilitates downstream differential abundance analysis using linear modeling frameworks based on limma, with explicit support for multivariable experimental designs including batch effects and other confounding covariates, as well as correlation-aware designs via duplicateCorrelation. License: MIT + file LICENSE URL: https://github.com/DataScienceRD-Almirall/ProteinBatcher BugReports: https://github.com/DataScienceRD-Almirall/ProteinBatcher/issues Encoding: UTF-8 Roxygen: list(markdown = TRUE) Imports: data.table, ggplot2, ggrepel, grDevices, grid, limma, methods, S4Vectors, stats, SummarizedExperiment, utils Suggests: knitr, rmarkdown, testthat (>= 3.0.0) VignetteBuilder: knitr biocViews: Proteomics, MassSpectrometry, DataImport, DataRepresentation, Software, BatchEffect Config/testthat/edition: 3 Config/roxygen2/version: 8.1.0 Config/pak/sysreqs: zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-08-21 16:59:35 UTC RemoteUrl: https://github.com/bioc/ProteinBatcher RemoteRef: HEAD RemoteSha: 1c6df35e6b9a0f0f333f23521ff00b7bd5ff508f NeedsCompilation: no Packaged: 2026-10-11 10:32:28 UTC; root Author: Aitor Moruno-Cuenca [aut, cre] (ORCID: ), Dr. Sergi Sayols-Puig [ctb] (ORCID: ), Dr. Bruna Oriol-Tordera [ctb] (ORCID: ), Dr. Hiba Salim [dtc] (ORCID: ), Dr. Francesc Fernández-Albert [ths] (ORCID: ), Prof. Dr. Alexandre Perera-Lluna [ths] (ORCID: ), Dr. Guadalupe Espadas-García [ctb, dtc] (ORCID: ), Dr. Elisa Monzón-Casanova [ctb, fnd] (ORCID: ), Prof. Dr. Eduard Sabidó-Aguade [res, ctb, dtc, fnd] (ORCID: ) Maintainer: Aitor Moruno-Cuenca