Package: PolySTest Title: PolySTest: Detection of differentially regulated features. Combined statistical testing for data with few replicates and missing values Version: 1.7.0 Authors@R: person("Veit", "Schwämmle", , "veits@bmb.sdu.dk", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-9708-6722")) Description: The complexity of high-throughput quantitative omics experiments often leads to low replicates numbers and many missing values. We implemented a new test to simultaneously consider missing values and quantitative changes, which we combined with well-performing statistical tests for high confidence detection of differentially regulated features. The package contains functions to run the test and to visualize the results. License: GPL-2 Encoding: UTF-8 biocViews: MassSpectrometry, Proteomics, Software, DifferentialExpression BugReports: https://github.com/computproteomics/PolySTest/issues URL: https://github.com/computproteomics/PolySTest Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Imports: fdrtool (>= 1.2.15), limma (>= 3.61.3), matrixStats (>= 0.57.0), qvalue (>= 2.22.0), shiny (>= 1.5.0), SummarizedExperiment (>= 1.20.0), knitr (>= 1.33), plotly (>= 4.9.4), heatmaply (>= 1.1.1), circlize (>= 0.4.12), UpSetR (>= 1.4.0), gplots (>= 3.1.1), S4Vectors (>= 0.30.0), parallel (>= 4.1.0), grDevices (>= 4.1.0), graphics (>= 4.1.0), stats (>= 4.1.0), utils (>= 4.1.0) Suggests: testthat (>= 3.0.0), BiocStyle VignetteBuilder: knitr Config/testthat/edition: 3 Depends: R (>= 4.4.0) Config/pak/sysreqs: cmake make libmagick++-dev gsfonts libicu-dev libuv1-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:03:22 UTC RemoteUrl: https://github.com/bioc/PolySTest RemoteRef: HEAD RemoteSha: 92e64516396520f37627f67bfafa3d5e381c3153 NeedsCompilation: no Packaged: 2026-07-15 05:01:05 UTC; root Author: Veit Schwämmle [aut, cre] (ORCID: ) Maintainer: Veit Schwämmle