Package: PoDCall Type: Package Title: Positive Droplet Calling for DNA Methylation Droplet Digital PCR Version: 1.21.1 Authors@R: c(person("Hans Petter", "Brodal", role=c("aut", "cre"), email="h.p.brodal@ous-research.no"), person("Marine", "Jeanmougin", role="aut", email="marine.jeanmougin@rr-research.no"), person("Guro Elisabeth", "Lind", role="aut", email="g.e.lind@ibv.uio.no")) Description: Reads files exported from 'QX Manager or QuantaSoft' containing amplitude values from a run of ddPCR (96 well plate) and robustly sets thresholds to determine positive droplets for each channel of each individual well. Concentration and normalized concentration in addition to other metrics is then calculated for each well. Results are returned as a table, optionally written to file, as well as optional plots (scatterplot and histogram) for both channels per well written to file. The package includes a shiny application which provides an interactive and user-friendly interface to the full functionality of PoDCall. License: GPL-3 Encoding: UTF-8 RoxygenNote: 7.3.3 Depends: R (>= 4.5) Imports: ggplot2, gridExtra, mclust, diptest, rlist, shiny, DT, LaplacesDemon, purrr, shinyjs, readr, grDevices, stats, utils, dplyr Suggests: knitr, rmarkdown, testthat, BiocStyle VignetteBuilder: knitr biocViews: Classification, Epigenetics, ddPCR, DifferentialMethylation, CpGIsland, DNAMethylation, StagedInstall: no Config/pak/sysreqs: cmake make libuv1-dev libxml2-dev libx11-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-07-17 07:33:10 UTC RemoteUrl: https://github.com/bioc/PoDCall RemoteRef: HEAD RemoteSha: 42f80025e80a40b3ff3218c33f723b881f5e6e44 NeedsCompilation: no Packaged: 2026-07-17 09:37:08 UTC; root Author: Hans Petter Brodal [aut, cre], Marine Jeanmougin [aut], Guro Elisabeth Lind [aut] Maintainer: Hans Petter Brodal