Package: Pigengene Type: Package Title: Infers biological signatures from gene expression data Version: 1.39.0 Date: 2016-03-31 Author: Habil Zare, Amir Foroushani, Rupesh Agrahari, Meghan Short, Isha Mehta, Neda Emami, and Sogand Sajedi Maintainer: Habil Zare biocViews: GeneExpression, RNASeq, NetworkInference, Network, GraphAndNetwork, BiomedicalInformatics, SystemsBiology, Transcriptomics, Classification, Clustering, DecisionTree, DimensionReduction, PrincipalComponent, Microarray, Normalization, ImmunoOncology Depends: R (>= 4.0.3), graph, BiocStyle (>= 2.28.0) Description: Pigengene package provides an efficient way to infer biological signatures from gene expression profiles. The signatures are independent from the underlying platform, e.g., the input can be microarray or RNA Seq data. It can even infer the signatures using data from one platform, and evaluate them on the other. Pigengene identifies the modules (clusters) of highly coexpressed genes using coexpression network analysis, summarizes the biological information of each module in an eigengene, learns a Bayesian network that models the probabilistic dependencies between modules, and builds a decision tree based on the expression of eigengenes. License: GPL (>=2) Imports: bnlearn (>= 4.7), C50 (>= 0.1.2), MASS, matrixStats, partykit, Rgraphviz, WGCNA, GO.db, impute, preprocessCore, grDevices, graphics, stats, utils, parallel, pheatmap (>= 1.0.8), dplyr, gdata, clusterProfiler, ReactomePA, ggplot2, openxlsx, DBI, DOSE Suggests: org.Hs.eg.db (>= 3.7.0), org.Mm.eg.db (>= 3.7.0), biomaRt (>= 2.30.0), knitr, AnnotationDbi, energy VignetteBuilder: knitr NeedsCompilation: no Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev libglpk-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:43:36 UTC RemoteUrl: https://github.com/bioc/Pigengene RemoteRef: HEAD RemoteSha: cc08c7aba6154b530e62af509efa2f5f7afb239c Packaged: 2026-07-04 00:34:34 UTC; root