{"Pathway":"REACT_268024","Pathway_name":"Intraflagellar transport","_row":"REACT_268024"} {"Pathway":"REACT_75842","Pathway_name":"Antigen processing: Ubiquitination & Proteasome degradation","_row":"REACT_75842"} {"Pathway":"REACT_116145","Pathway_name":"PPARA activates gene expression","_row":"REACT_116145"} {"Pathway":"REACT_27161","Pathway_name":"Transcriptional regulation of white adipocyte differentiation","_row":"REACT_27161"} {"Pathway":"REACT_163701","Pathway_name":"FCERI mediated MAPK activation","_row":"REACT_163701"} {"Pathway":"REACT_163769","Pathway_name":"Role of LAT2/NTAL/LAB on calcium mobilization","_row":"REACT_163769"} {"Pathway":"REACT_8024","Pathway_name":"Initial triggering of complement","_row":"REACT_8024"} {"Pathway":"REACT_7956","Pathway_name":"Classical antibody-mediated complement activation","_row":"REACT_7956"} {"Pathway":"REACT_163994","Pathway_name":"FCERI mediated NF-kB activation","_row":"REACT_163994"} {"Pathway":"REACT_160163","Pathway_name":"Scavenging of heme from plasma","_row":"REACT_160163"} {"Pathway":"REACT_163936","Pathway_name":"Fc epsilon receptor (FCERI) signaling","_row":"REACT_163936"} {"Pathway":"REACT_160158","Pathway_name":"Role of phospholipids in phagocytosis","_row":"REACT_160158"} {"Pathway":"REACT_163834","Pathway_name":"FCERI mediated Ca+2 mobilization","_row":"REACT_163834"} {"Pathway":"REACT_11152","Pathway_name":"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell","_row":"REACT_11152"} {"Pathway":"REACT_160274","Pathway_name":"FCGR activation","_row":"REACT_160274"} {"Pathway":"REACT_118700","Pathway_name":"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers","_row":"REACT_118700"} {"Pathway":"REACT_160086","Pathway_name":"Regulation of actin dynamics for phagocytic cup formation","_row":"REACT_160086"} {"Pathway":"REACT_22365","Pathway_name":"Recycling pathway of L1","_row":"REACT_22365"} {"Pathway":"REACT_121408","Pathway_name":"A tetrasaccharide linker sequence is required for GAG synthesis","_row":"REACT_121408"} {"Pathway":"REACT_11051","Pathway_name":"Rho GTPase cycle","_row":"REACT_11051"} {"Pathway":"REACT_13528","Pathway_name":"Regulation of PAK-2p34 activity by PS-GAP/RHG10","_row":"REACT_13528"} {"Pathway":"REACT_160189","Pathway_name":"Stimuli-sensing channels","_row":"REACT_160189"} {"Pathway":"REACT_75925","Pathway_name":"Amyloids","_row":"REACT_75925"} {"Pathway":"REACT_380","Pathway_name":"Synthesis of very long-chain fatty acyl-CoAs","_row":"REACT_380"} {"Pathway":"REACT_12627","Pathway_name":"Generic Transcription Pathway","_row":"REACT_12627"} {"Pathway":"REACT_264269","Pathway_name":"O-glycosylation of TSR domain-containing proteins","_row":"REACT_264269"} {"Pathway":"REACT_15488","Pathway_name":"Olfactory Signaling Pathway","_row":"REACT_15488"} {"Pathway":"REACT_6359","Pathway_name":"Budding and maturation of HIV virion","_row":"REACT_6359"} {"Pathway":"REACT_27258","Pathway_name":"Endosomal Sorting Complex Required For Transport (ESCRT)","_row":"REACT_27258"} {"Pathway":"REACT_115893","Pathway_name":"Membrane binding and targetting of GAG proteins","_row":"REACT_115893"} {"Pathway":"REACT_1221","Pathway_name":"CDK-mediated phosphorylation and removal of Cdc6","_row":"REACT_1221"} {"Pathway":"REACT_9453","Pathway_name":"Vif-mediated degradation of APOBEC3G","_row":"REACT_9453"} {"Pathway":"REACT_13565","Pathway_name":"Regulation of ornithine decarboxylase (ODC)","_row":"REACT_13565"} {"Pathway":"REACT_1614","Pathway_name":"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A","_row":"REACT_1614"} {"Pathway":"REACT_264605","Pathway_name":"Hedgehog ligand biogenesis","_row":"REACT_264605"} {"Pathway":"REACT_6761","Pathway_name":"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1","_row":"REACT_6761"} {"Pathway":"REACT_150471","Pathway_name":"Separation of Sister Chromatids","_row":"REACT_150471"} {"Pathway":"REACT_1156","Pathway_name":"Orc1 removal from chromatin","_row":"REACT_1156"} {"Pathway":"REACT_6871","Pathway_name":"APC/C:Cdc20 mediated degradation of Securin","_row":"REACT_6871"} {"Pathway":"REACT_25325","Pathway_name":"AUF1 (hnRNP D0) destabilizes mRNA","_row":"REACT_25325"} {"Pathway":"REACT_11063","Pathway_name":"Degradation of beta-catenin by the destruction complex","_row":"REACT_11063"} {"Pathway":"REACT_268718","Pathway_name":"Hedgehog 'on' state","_row":"REACT_268718"} {"Pathway":"REACT_188330","Pathway_name":"Dectin-1 mediated noncanonical NF-kB signaling","_row":"REACT_188330"} {"Pathway":"REACT_6850","Pathway_name":"Cdc20:Phospho-APC/C mediated degradation of Cyclin A","_row":"REACT_6850"} {"Pathway":"REACT_9031","Pathway_name":"Vpu mediated degradation of CD4","_row":"REACT_9031"} {"Pathway":"REACT_188323","Pathway_name":"CLEC7A (Dectin-1) signaling","_row":"REACT_188323"} {"Pathway":"REACT_13464","Pathway_name":"Regulation of activated PAK-2p34 by proteasome mediated degradation","_row":"REACT_13464"} {"Pathway":"REACT_263883","Pathway_name":"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD","_row":"REACT_263883"} {"Pathway":"REACT_4","Pathway_name":"Ubiquitin-dependent degradation of Cyclin D1","_row":"REACT_4"} {"Pathway":"REACT_20549","Pathway_name":"Autodegradation of the E3 ubiquitin ligase COP1","_row":"REACT_20549"} {"Pathway":"REACT_118656","Pathway_name":"Activation of NF-kappaB in B cells","_row":"REACT_118656"} {"Pathway":"REACT_264478","Pathway_name":"Asymmetric localization of PCP proteins","_row":"REACT_264478"} {"Pathway":"REACT_6821","Pathway_name":"SCF-beta-TrCP mediated degradation of Emi1","_row":"REACT_6821"} {"Pathway":"REACT_263873","Pathway_name":"degradation of AXIN","_row":"REACT_263873"} {"Pathway":"REACT_111056","Pathway_name":"Cross-presentation of soluble exogenous antigens (endosomes)","_row":"REACT_111056"} {"Pathway":"REACT_268156","Pathway_name":"Degradation of GLI1 by the proteasome","_row":"REACT_268156"} {"Pathway":"REACT_264438","Pathway_name":"degradation of DVL","_row":"REACT_264438"} {"Pathway":"REACT_1949","Pathway_name":"CDT1 association with the CDC6:ORC:origin complex","_row":"REACT_1949"} {"Pathway":"REACT_268366","Pathway_name":"GLI3 is processed to GLI3R by the proteasome","_row":"REACT_268366"} {"Pathway":"REACT_111178","Pathway_name":"ER-Phagosome pathway","_row":"REACT_111178"} {"Pathway":"REACT_267700","Pathway_name":"Degradation of GLI2 by the proteasome","_row":"REACT_267700"} {"Pathway":"REACT_25387","Pathway_name":"Ligand-gated ion channel transport","_row":"REACT_25387"} {"Pathway":"REACT_20514","Pathway_name":"Deadenylation of mRNA","_row":"REACT_20514"} {"Pathway":"REACT_571","Pathway_name":"RNA Polymerase III Transcription Initiation From Type 3 Promoter","_row":"REACT_571"} {"Pathway":"REACT_347","Pathway_name":"RNA Polymerase III Transcription Initiation From Type 1 Promoter","_row":"REACT_347"} {"Pathway":"REACT_22339","Pathway_name":"RNA Polymerase III Abortive And Retractive Initiation","_row":"REACT_22339"} {"Pathway":"REACT_1036","Pathway_name":"RNA Polymerase III Transcription Initiation From Type 2 Promoter","_row":"REACT_1036"} {"Pathway":"REACT_494","Pathway_name":"Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis","_row":"REACT_494"} {"Pathway":"REACT_355372","Pathway_name":"RHO GTPases Activate WASPs and WAVEs","_row":"REACT_355372"} {"Pathway":"REACT_264461","Pathway_name":"Aflatoxin activation and detoxification","_row":"REACT_264461"} {"Pathway":"REACT_6960","Pathway_name":"Glutathione synthesis and recycling","_row":"REACT_6960"} {"Pathway":"REACT_268425","Pathway_name":"Trafficking of myristoylated proteins to the cilium","_row":"REACT_268425"} {"Pathway":"REACT_147694","Pathway_name":"DAP12 interactions","_row":"REACT_147694"} {"Pathway":"REACT_16888","Pathway_name":"Signaling by PDGF","_row":"REACT_16888"} {"Pathway":"REACT_18312","Pathway_name":"NCAM1 interactions","_row":"REACT_18312"} {"Pathway":"REACT_150401","Pathway_name":"Collagen degradation","_row":"REACT_150401"} {"Pathway":"REACT_163906","Pathway_name":"ECM proteoglycans","_row":"REACT_163906"} {"Pathway":"REACT_13552","Pathway_name":"Integrin cell surface interactions","_row":"REACT_13552"} {"Pathway":"REACT_121139","Pathway_name":"Collagen biosynthesis and modifying enzymes","_row":"REACT_121139"} {"Pathway":"REACT_150180","Pathway_name":"Assembly of collagen fibrils and other multimeric structures","_row":"REACT_150180"} {"Pathway":"REACT_147867","Pathway_name":"Translocation of GLUT4 to the plasma membrane","_row":"REACT_147867"} {"Pathway":"REACT_264256","Pathway_name":"Release of Hh-Np from the secreting cell","_row":"REACT_264256"} {"Pathway":"REACT_267753","Pathway_name":"Activation of SMO","_row":"REACT_267753"} {"Pathway":"REACT_15451","Pathway_name":"Loss of proteins required for interphase microtubule organization from the centrosome","_row":"REACT_15451"} {"Pathway":"REACT_15364","Pathway_name":"Loss of Nlp from mitotic centrosomes","_row":"REACT_15364"} {"Pathway":"REACT_160315","Pathway_name":"Regulation of PLK1 Activity at G2/M Transition","_row":"REACT_160315"} {"Pathway":"REACT_267965","Pathway_name":"Anchoring of the basal body to the plasma membrane","_row":"REACT_267965"} {"Pathway":"REACT_15296","Pathway_name":"Recruitment of mitotic centrosome proteins and complexes","_row":"REACT_15296"} {"Pathway":"REACT_25168","Pathway_name":"GABA A (rho) receptor activation","_row":"REACT_25168"} {"Pathway":"REACT_118614","Pathway_name":"Activated NOTCH1 Transmits Signal to the Nucleus","_row":"REACT_118614"} {"Pathway":"REACT_160089","Pathway_name":"Constitutive Signaling by NOTCH1 HD Domain Mutants","_row":"REACT_160089"} {"Pathway":"REACT_160254","Pathway_name":"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants","_row":"REACT_160254"} {"Pathway":"REACT_160243","Pathway_name":"Constitutive Signaling by NOTCH1 PEST Domain Mutants","_row":"REACT_160243"} {"Pathway":"REACT_160205","Pathway_name":"NOTCH2 Activation and Transmission of Signal to the Nucleus","_row":"REACT_160205"} {"Pathway":"REACT_22186","Pathway_name":"Deposition of new CENPA-containing nucleosomes at the centromere","_row":"REACT_22186"} {"Pathway":"REACT_15333","Pathway_name":"Adenylate cyclase inhibitory pathway","_row":"REACT_15333"} {"Pathway":"REACT_15426","Pathway_name":"PLC beta mediated events","_row":"REACT_15426"} {"Pathway":"REACT_19327","Pathway_name":"G alpha (s) signalling events","_row":"REACT_19327"} {"Pathway":"REACT_15457","Pathway_name":"G-protein activation","_row":"REACT_15457"} {"Pathway":"REACT_19333","Pathway_name":"G alpha (z) signalling events","_row":"REACT_19333"} {"Pathway":"REACT_19231","Pathway_name":"G alpha (i) signalling events","_row":"REACT_19231"} {"Pathway":"REACT_20653","Pathway_name":"ADP signalling through P2Y purinoceptor 12","_row":"REACT_20653"} {"Pathway":"REACT_24019","Pathway_name":"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)","_row":"REACT_24019"} {"Pathway":"REACT_267948","Pathway_name":"BBSome-mediated cargo-targeting to cilium","_row":"REACT_267948"} {"Pathway":"REACT_163875","Pathway_name":"Sperm Motility And Taxes","_row":"REACT_163875"} {"Pathway":"REACT_115831","Pathway_name":"ISG15 antiviral mechanism","_row":"REACT_115831"} {"Pathway":"REACT_19287","Pathway_name":"Lysosome Vesicle Biogenesis","_row":"REACT_19287"} {"Pathway":"REACT_1407","Pathway_name":"Plasmalogen biosynthesis","_row":"REACT_1407"} {"Pathway":"REACT_682","Pathway_name":"Mitotic Prometaphase","_row":"REACT_682"} {"Pathway":"REACT_355252","Pathway_name":"RHO GTPases Activate Formins","_row":"REACT_355252"} {"Pathway":"REACT_150425","Pathway_name":"Resolution of Sister Chromatid Cohesion","_row":"REACT_150425"} {"Pathway":"REACT_121399","Pathway_name":"MHC class II antigen presentation","_row":"REACT_121399"} {"Pathway":"REACT_25201","Pathway_name":"Kinesins","_row":"REACT_25201"} {"Pathway":"REACT_471","Pathway_name":"E2F mediated regulation of DNA replication","_row":"REACT_471"} {"Pathway":"REACT_655","Pathway_name":"Pyrimidine salvage reactions","_row":"REACT_655"} {"Pathway":"REACT_683","Pathway_name":"G1/S-Specific Transcription","_row":"REACT_683"} {"Pathway":"REACT_18372","Pathway_name":"Class B/2 (Secretin family receptors)","_row":"REACT_18372"} {"Pathway":"REACT_19187","Pathway_name":"Clathrin derived vesicle budding","_row":"REACT_19187"} {"Pathway":"REACT_25149","Pathway_name":"Ion transport by P-type ATPases","_row":"REACT_25149"} {"Pathway":"REACT_75779","Pathway_name":"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)","_row":"REACT_75779"} {"Pathway":"REACT_27283","Pathway_name":"Interleukin-2 signaling","_row":"REACT_27283"} {"Pathway":"REACT_1178","Pathway_name":"Disinhibition of SNARE formation","_row":"REACT_1178"} {"Pathway":"REACT_163810","Pathway_name":"Ficolins bind to repetitive carbohydrate structures on the target cell surface","_row":"REACT_163810"} {"Pathway":"REACT_7964","Pathway_name":"Lectin pathway of complement activation","_row":"REACT_7964"} {"Pathway":"REACT_19400","Pathway_name":"Golgi Associated Vesicle Biogenesis","_row":"REACT_19400"} {"Pathway":"REACT_6913","Pathway_name":"Cytosolic sulfonation of small molecules","_row":"REACT_6913"} {"Pathway":"REACT_25351","Pathway_name":"TRAF6 mediated induction of TAK1 complex","_row":"REACT_25351"} {"Pathway":"REACT_355462","Pathway_name":"IRAK4 deficiency (TLR2/4)","_row":"REACT_355462"} {"Pathway":"REACT_25374","Pathway_name":"IKK complex recruitment mediated by RIP1","_row":"REACT_25374"} {"Pathway":"REACT_1503","Pathway_name":"Ligand-dependent caspase activation","_row":"REACT_1503"} {"Pathway":"REACT_6894","Pathway_name":"Toll Like Receptor 4 (TLR4) Cascade","_row":"REACT_6894"} {"Pathway":"REACT_6788","Pathway_name":"MyD88:Mal cascade initiated on plasma membrane","_row":"REACT_6788"} {"Pathway":"REACT_6809","Pathway_name":"MyD88-independent TLR3/TLR4 cascade ","_row":"REACT_6809"} {"Pathway":"REACT_150361","Pathway_name":"TRIF-mediated programmed cell death","_row":"REACT_150361"} {"Pathway":"REACT_355210","Pathway_name":"MyD88 deficiency (TLR2/4)","_row":"REACT_355210"} {"Pathway":"REACT_25148","Pathway_name":"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon","_row":"REACT_25148"} {"Pathway":"REACT_22393","Pathway_name":"Respiratory electron transport","_row":"REACT_22393"} {"Pathway":"REACT_121301","Pathway_name":"Hyaluronan biosynthesis and export","_row":"REACT_121301"} {"Pathway":"REACT_164011","Pathway_name":"Regulation by c-FLIP","_row":"REACT_164011"} {"Pathway":"REACT_832","Pathway_name":"Dimerization of procaspase-8","_row":"REACT_832"} {"Pathway":"REACT_402","Pathway_name":"TRAIL signaling","_row":"REACT_402"} {"Pathway":"REACT_355311","Pathway_name":"CASP8 activity is inhibited","_row":"REACT_355311"} {"Pathway":"REACT_355409","Pathway_name":"RIPK1-mediated regulated necrosis","_row":"REACT_355409"} {"Pathway":"REACT_18319","Pathway_name":"Class C/3 (Metabotropic glutamate/pheromone receptors)","_row":"REACT_18319"} {"Pathway":"REACT_6785","Pathway_name":"Autodegradation of Cdh1 by Cdh1:APC/C","_row":"REACT_6785"} {"Pathway":"REACT_9003","Pathway_name":"SCF(Skp2)-mediated degradation of p27/p21","_row":"REACT_9003"} {"Pathway":"REACT_12034","Pathway_name":"Signaling by BMP","_row":"REACT_12034"} {"Pathway":"REACT_23916","Pathway_name":"Signal regulatory protein (SIRP) family interactions","_row":"REACT_23916"} {"Pathway":"REACT_264249","Pathway_name":"Detoxification of Reactive Oxygen Species","_row":"REACT_264249"} {"Pathway":"REACT_21384","Pathway_name":"Thrombin signalling through proteinase activated receptors (PARs)","_row":"REACT_21384"} {"Pathway":"REACT_18283","Pathway_name":"G alpha (q) signalling events","_row":"REACT_18283"} {"Pathway":"REACT_14819","Pathway_name":"Peptide ligand-binding receptors","_row":"REACT_14819"} {"Pathway":"REACT_264242","Pathway_name":"formation of the beta-catenin:TCF transactivating complex","_row":"REACT_264242"} {"Pathway":"REACT_355469","Pathway_name":"RHO GTPases activate IQGAPs","_row":"REACT_355469"} {"Pathway":"REACT_264178","Pathway_name":"deactivation of the beta-catenin transactivating complex","_row":"REACT_264178"} {"Pathway":"REACT_120734","Pathway_name":"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription","_row":"REACT_120734"} {"Pathway":"REACT_169436","Pathway_name":"Oxidative Stress Induced Senescence","_row":"REACT_169436"} {"Pathway":"REACT_355174","Pathway_name":"SUMOylation of DNA damage response and repair proteins","_row":"REACT_355174"} {"Pathway":"REACT_6346","Pathway_name":"Formation of HIV-1 elongation complex containing HIV-1 Tat","_row":"REACT_6346"} {"Pathway":"REACT_6261","Pathway_name":"Abortive elongation of HIV-1 transcript in the absence of Tat","_row":"REACT_6261"} {"Pathway":"REACT_1470","Pathway_name":"mRNA Capping","_row":"REACT_1470"} {"Pathway":"REACT_846","Pathway_name":"Formation of the Early Elongation Complex","_row":"REACT_846"} {"Pathway":"REACT_6162","Pathway_name":"Tat-mediated elongation of the HIV-1 transcript","_row":"REACT_6162"} {"Pathway":"REACT_6344","Pathway_name":"Tat-mediated HIV elongation arrest and recovery","_row":"REACT_6344"} {"Pathway":"REACT_975","Pathway_name":"RNA Pol II CTD phosphorylation and interaction with CE","_row":"REACT_975"} {"Pathway":"REACT_22107","Pathway_name":"RNA Polymerase II Pre-transcription Events","_row":"REACT_22107"} {"Pathway":"REACT_6143","Pathway_name":"Pausing and recovery of Tat-mediated HIV elongation","_row":"REACT_6143"} {"Pathway":"REACT_1845","Pathway_name":"Formation of RNA Pol II elongation complex ","_row":"REACT_1845"} {"Pathway":"REACT_6259","Pathway_name":"HIV elongation arrest and recovery","_row":"REACT_6259"} {"Pathway":"REACT_6237","Pathway_name":"RNA Pol II CTD phosphorylation and interaction with CE","_row":"REACT_6237"} {"Pathway":"REACT_6244","Pathway_name":"Pausing and recovery of HIV elongation","_row":"REACT_6244"} {"Pathway":"REACT_22201","Pathway_name":"Formation of HIV elongation complex in the absence of HIV Tat","_row":"REACT_22201"} {"Pathway":"REACT_6319","Pathway_name":"Formation of the HIV-1 Early Elongation Complex","_row":"REACT_6319"} {"Pathway":"REACT_833","Pathway_name":"RNA Polymerase II Transcription Elongation","_row":"REACT_833"} {"Pathway":"REACT_2089","Pathway_name":"RNA Polymerase II Promoter Escape","_row":"REACT_2089"} {"Pathway":"REACT_6332","Pathway_name":"HIV Transcription Initiation","_row":"REACT_6332"} {"Pathway":"REACT_1655","Pathway_name":"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening","_row":"REACT_1655"} {"Pathway":"REACT_834","Pathway_name":"RNA Polymerase II Transcription Initiation And Promoter Clearance","_row":"REACT_834"} {"Pathway":"REACT_6253","Pathway_name":"RNA Polymerase II HIV Promoter Escape","_row":"REACT_6253"} {"Pathway":"REACT_1851","Pathway_name":"RNA Polymerase II Transcription Initiation","_row":"REACT_1851"} {"Pathway":"REACT_6233","Pathway_name":"Transcription of the HIV genome","_row":"REACT_6233"} {"Pathway":"REACT_21268","Pathway_name":"Free fatty acid receptors","_row":"REACT_21268"} {"Pathway":"REACT_13462","Pathway_name":"Activation of DNA fragmentation factor","_row":"REACT_13462"} {"Pathway":"REACT_111059","Pathway_name":"Regulation of signaling by NODAL","_row":"REACT_111059"} {"Pathway":"REACT_318","Pathway_name":"Platelet degranulation ","_row":"REACT_318"} {"Pathway":"REACT_111057","Pathway_name":"Signaling by NODAL","_row":"REACT_111057"} {"Pathway":"REACT_931","Pathway_name":"Ribosomal scanning and start codon recognition","_row":"REACT_931"} {"Pathway":"REACT_1979","Pathway_name":"Translation initiation complex formation","_row":"REACT_1979"} {"Pathway":"REACT_1079","Pathway_name":"Formation of the ternary complex, and subsequently, the 43S complex","_row":"REACT_1079"} {"Pathway":"REACT_2085","Pathway_name":"GTP hydrolysis and joining of the 60S ribosomal subunit","_row":"REACT_2085"} {"Pathway":"REACT_1797","Pathway_name":"Formation of a pool of free 40S subunits","_row":"REACT_1797"} {"Pathway":"REACT_79","Pathway_name":"L13a-mediated translational silencing of Ceruloplasmin expression","_row":"REACT_79"} {"Pathway":"REACT_13606","Pathway_name":"Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels","_row":"REACT_13606"} {"Pathway":"REACT_6769","Pathway_name":"Activation of ATR in response to replication stress","_row":"REACT_6769"} {"Pathway":"REACT_1095","Pathway_name":"Activation of the pre-replicative complex","_row":"REACT_1095"} {"Pathway":"REACT_111118","Pathway_name":"BMAL1:CLOCK,NPAS2 activates circadian gene expression","_row":"REACT_111118"} {"Pathway":"REACT_118659","Pathway_name":"RORA activates gene expression","_row":"REACT_118659"} {"Pathway":"REACT_24941","Pathway_name":"Circadian Clock","_row":"REACT_24941"} {"Pathway":"REACT_121025","Pathway_name":"Synthesis of PIPs at the plasma membrane","_row":"REACT_121025"} {"Pathway":"REACT_23891","Pathway_name":"Interleukin receptor SHC signaling","_row":"REACT_23891"} {"Pathway":"REACT_19290","Pathway_name":"G beta:gamma signalling through PI3Kgamma","_row":"REACT_19290"} {"Pathway":"REACT_75829","Pathway_name":"PIP3 activates AKT signaling","_row":"REACT_75829"} {"Pathway":"REACT_147727","Pathway_name":"Constitutive Signaling by Aberrant PI3K in Cancer","_row":"REACT_147727"} {"Pathway":"REACT_23787","Pathway_name":"Regulation of signaling by CBL","_row":"REACT_23787"} {"Pathway":"REACT_1695","Pathway_name":"GPVI-mediated activation cascade","_row":"REACT_1695"} {"Pathway":"REACT_23837","Pathway_name":"Interleukin-3, 5 and GM-CSF signaling","_row":"REACT_23837"} {"Pathway":"REACT_12528","Pathway_name":"Regulation of pyruvate dehydrogenase (PDH) complex","_row":"REACT_12528"} {"Pathway":"REACT_2071","Pathway_name":"Pyruvate metabolism","_row":"REACT_2071"} {"Pathway":"REACT_267785","Pathway_name":"Signaling by Retinoic Acid","_row":"REACT_267785"} {"Pathway":"REACT_1206","Pathway_name":"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane","_row":"REACT_1206"} {"Pathway":"REACT_19397","Pathway_name":"Transport of inorganic cations/anions and amino acids/oligopeptides","_row":"REACT_19397"} {"Pathway":"REACT_12591","Pathway_name":"Glutamate Neurotransmitter Release Cycle","_row":"REACT_12591"} {"Pathway":"REACT_18289","Pathway_name":"P2Y receptors","_row":"REACT_18289"} {"Pathway":"REACT_22285","Pathway_name":"Transport of vitamins, nucleosides, and related molecules","_row":"REACT_22285"} {"Pathway":"REACT_263952","Pathway_name":"EPHB-mediated forward signaling","_row":"REACT_263952"} {"Pathway":"REACT_12541","Pathway_name":"NOSTRIN mediated eNOS trafficking","_row":"REACT_12541"} {"Pathway":"REACT_22351","Pathway_name":"DCC mediated attractive signaling","_row":"REACT_22351"} {"Pathway":"REACT_23832","Pathway_name":"Nephrin interactions","_row":"REACT_23832"} {"Pathway":"REACT_23767","Pathway_name":"cGMP effects","_row":"REACT_23767"} {"Pathway":"REACT_9434","Pathway_name":"vRNP Assembly","_row":"REACT_9434"} {"Pathway":"REACT_367","Pathway_name":"Mitochondrial transcription initiation","_row":"REACT_367"} {"Pathway":"REACT_264212","Pathway_name":"Transcriptional activation of mitochondrial biogenesis","_row":"REACT_264212"} {"Pathway":"REACT_6772","Pathway_name":"S6K1 signalling","_row":"REACT_6772"} {"Pathway":"REACT_15344","Pathway_name":"Chemokine receptors bind chemokines","_row":"REACT_15344"} {"Pathway":"REACT_263965","Pathway_name":"NoRC negatively regulates rRNA expression","_row":"REACT_263965"} {"Pathway":"REACT_263923","Pathway_name":"HDACs deacetylate histones","_row":"REACT_263923"} {"Pathway":"REACT_22166","Pathway_name":"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA","_row":"REACT_22166"} {"Pathway":"REACT_995","Pathway_name":"Apoptotic execution phase","_row":"REACT_995"} {"Pathway":"REACT_120756","Pathway_name":"Synthesis of PIPs at the early endosome membrane","_row":"REACT_120756"} {"Pathway":"REACT_120836","Pathway_name":"Synthesis of PIPs at the Golgi membrane","_row":"REACT_120836"} {"Pathway":"REACT_120918","Pathway_name":"Synthesis of PIPs at the late endosome membrane","_row":"REACT_120918"} {"Pathway":"REACT_18325","Pathway_name":"Regulation of insulin secretion","_row":"REACT_18325"} {"Pathway":"REACT_12555","Pathway_name":"Downstream TCR signaling","_row":"REACT_12555"} {"Pathway":"REACT_19344","Pathway_name":"Costimulation by the CD28 family","_row":"REACT_19344"} {"Pathway":"REACT_264464","Pathway_name":"VEGFA-VEGFR2 Pathway","_row":"REACT_264464"} {"Pathway":"REACT_111040","Pathway_name":"Signaling by SCF-KIT","_row":"REACT_111040"} {"Pathway":"REACT_147814","Pathway_name":"DAP12 signaling","_row":"REACT_147814"} {"Pathway":"REACT_12464","Pathway_name":"PI3K/AKT activation","_row":"REACT_12464"} {"Pathway":"REACT_115529","Pathway_name":"Interleukin-7 signaling","_row":"REACT_115529"} {"Pathway":"REACT_18407","Pathway_name":"G alpha (12/13) signalling events","_row":"REACT_18407"} {"Pathway":"REACT_976","Pathway_name":"PI3K Cascade","_row":"REACT_976"} {"Pathway":"REACT_19358","Pathway_name":"CD28 dependent PI3K/Akt signaling","_row":"REACT_19358"} {"Pathway":"REACT_12621","Pathway_name":"Tie2 Signaling","_row":"REACT_12621"} {"Pathway":"REACT_17025","Pathway_name":"Downstream signal transduction","_row":"REACT_17025"} {"Pathway":"REACT_268749","Pathway_name":"Defective B4GALT7 causes EDS, progeroid type","_row":"REACT_268749"} {"Pathway":"REACT_267741","Pathway_name":"Defective EXT2 causes exostoses 2","_row":"REACT_267741"} {"Pathway":"REACT_268678","Pathway_name":"Defective B3GAT3 causes JDSSDHD","_row":"REACT_268678"} {"Pathway":"REACT_163874","Pathway_name":"Non-integrin membrane-ECM interactions","_row":"REACT_163874"} {"Pathway":"REACT_267942","Pathway_name":"Defective EXT1 causes exostoses 1, TRPS2 and CHDS","_row":"REACT_267942"} {"Pathway":"REACT_121248","Pathway_name":"HS-GAG biosynthesis","_row":"REACT_121248"} {"Pathway":"REACT_120752","Pathway_name":"HS-GAG degradation","_row":"REACT_120752"} {"Pathway":"REACT_24968","Pathway_name":"Retinoid metabolism and transport","_row":"REACT_24968"} {"Pathway":"REACT_268299","Pathway_name":"VxPx cargo-targeting to cilium","_row":"REACT_268299"} {"Pathway":"REACT_15550","Pathway_name":"Insulin processing","_row":"REACT_15550"} {"Pathway":"REACT_13778","Pathway_name":"Regulation of gene expression in early pancreatic precursor cells","_row":"REACT_13778"} {"Pathway":"REACT_15525","Pathway_name":"Nuclear Receptor transcription pathway","_row":"REACT_15525"} {"Pathway":"REACT_19373","Pathway_name":"Tight junction interactions","_row":"REACT_19373"} {"Pathway":"REACT_22292","Pathway_name":"CHL1 interactions","_row":"REACT_22292"} {"Pathway":"REACT_118636","Pathway_name":"Signaling by NOTCH4","_row":"REACT_118636"} {"Pathway":"REACT_160106","Pathway_name":"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant","_row":"REACT_160106"} {"Pathway":"REACT_118862","Pathway_name":"Signaling by NOTCH3","_row":"REACT_118862"} {"Pathway":"REACT_264047","Pathway_name":"Ephrin signaling","_row":"REACT_264047"} {"Pathway":"REACT_22312","Pathway_name":"Neurofascin interactions","_row":"REACT_22312"} {"Pathway":"REACT_16907","Pathway_name":"Association of TriC/CCT with target proteins during 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complex","_row":"REACT_1181"} {"Pathway":"REACT_163710","Pathway_name":"WNT ligand biogenesis and trafficking","_row":"REACT_163710"} {"Pathway":"REACT_21330","Pathway_name":"Synthesis and interconversion of nucleotide di- and triphosphates","_row":"REACT_21330"} {"Pathway":"REACT_1520","Pathway_name":"Gluconeogenesis","_row":"REACT_1520"} {"Pathway":"REACT_6904","Pathway_name":"Phosphorylation of the APC/C","_row":"REACT_6904"} {"Pathway":"REACT_1072","Pathway_name":"Inactivation of APC/C via direct inhibition of the APC/C complex","_row":"REACT_1072"} {"Pathway":"REACT_8017","Pathway_name":"APC-Cdc20 mediated degradation of Nek2A","_row":"REACT_8017"} {"Pathway":"REACT_6867","Pathway_name":"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase","_row":"REACT_6867"} {"Pathway":"REACT_6781","Pathway_name":"APC/C:Cdc20 mediated degradation of mitotic proteins","_row":"REACT_6781"} {"Pathway":"REACT_169168","Pathway_name":"Senescence-Associated Secretory Phenotype (SASP)","_row":"REACT_169168"} {"Pathway":"REACT_6837","Pathway_name":"Regulation of APC/C activators between G1/S and early anaphase","_row":"REACT_6837"} {"Pathway":"REACT_6820","Pathway_name":"APC/C:Cdc20 mediated degradation of Cyclin B","_row":"REACT_6820"} {"Pathway":"REACT_169312","Pathway_name":"Defective HLCS causes multiple carboxylase deficiency","_row":"REACT_169312"} {"Pathway":"REACT_2122","Pathway_name":"ChREBP activates metabolic gene expression","_row":"REACT_2122"} {"Pathway":"REACT_11082","Pathway_name":"Import of palmitoyl-CoA into the mitochondrial matrix","_row":"REACT_11082"} {"Pathway":"REACT_147904","Pathway_name":"Activation of gene expression by SREBF (SREBP)","_row":"REACT_147904"} {"Pathway":"REACT_11153","Pathway_name":"Biotin transport and metabolism","_row":"REACT_11153"} {"Pathway":"REACT_25012","Pathway_name":"Vitamins B6 activation to pyridoxal phosphate","_row":"REACT_25012"} {"Pathway":"REACT_111225","Pathway_name":"Regulation of KIT 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in ERBB4 signaling","_row":"REACT_116005"} {"Pathway":"REACT_116008","Pathway_name":"PI3K events in ERBB2 signaling","_row":"REACT_116008"} {"Pathway":"REACT_115896","Pathway_name":"GRB7 events in ERBB2 signaling","_row":"REACT_115896"} {"Pathway":"REACT_115596","Pathway_name":"Signaling by ERBB4","_row":"REACT_115596"} {"Pathway":"REACT_115961","Pathway_name":"PI3K events in ERBB4 signaling","_row":"REACT_115961"} {"Pathway":"REACT_23809","Pathway_name":"Transport of glycerol from adipocytes to the liver by Aquaporins","_row":"REACT_23809"} {"Pathway":"REACT_23826","Pathway_name":"Passive transport by Aquaporins","_row":"REACT_23826"} {"Pathway":"REACT_1785","Pathway_name":"Citric acid cycle (TCA cycle)","_row":"REACT_1785"} {"Pathway":"REACT_19199","Pathway_name":"CRMPs in Sema3A signaling","_row":"REACT_19199"} {"Pathway":"REACT_25216","Pathway_name":"Regulation of IFNA signaling","_row":"REACT_25216"} {"Pathway":"REACT_27307","Pathway_name":"Interleukin-6 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{"Pathway":"REACT_120888","Pathway_name":"CS/DS degradation","_row":"REACT_120888"} {"Pathway":"REACT_267648","Pathway_name":"Defective CHST3 causes SEDCJD","_row":"REACT_267648"} {"Pathway":"REACT_22205","Pathway_name":"L1CAM interactions","_row":"REACT_22205"} {"Pathway":"REACT_120989","Pathway_name":"Chondroitin sulfate biosynthesis","_row":"REACT_120989"} {"Pathway":"REACT_18273","Pathway_name":"XBP1(S) activates chaperone genes","_row":"REACT_18273"} {"Pathway":"REACT_23946","Pathway_name":"Prostacyclin signalling through prostacyclin receptor","_row":"REACT_23946"} {"Pathway":"REACT_75831","Pathway_name":"Activation of G protein gated Potassium channels","_row":"REACT_75831"} {"Pathway":"REACT_18274","Pathway_name":"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion","_row":"REACT_18274"} {"Pathway":"REACT_19140","Pathway_name":"ADP signalling through P2Y purinoceptor 1","_row":"REACT_19140"} {"Pathway":"REACT_24023","Pathway_name":"Vasopressin regulates renal water homeostasis via Aquaporins","_row":"REACT_24023"} {"Pathway":"REACT_18377","Pathway_name":"Glucagon-type ligand receptors","_row":"REACT_18377"} {"Pathway":"REACT_19145","Pathway_name":"G beta:gamma signalling through PLC beta","_row":"REACT_19145"} {"Pathway":"REACT_18339","Pathway_name":"Adrenaline,noradrenaline inhibits insulin secretion","_row":"REACT_18339"} {"Pathway":"REACT_21254","Pathway_name":"Presynaptic function of Kainate receptors","_row":"REACT_21254"} {"Pathway":"REACT_263982","Pathway_name":"Ca2+ pathway","_row":"REACT_263982"} {"Pathway":"REACT_20647","Pathway_name":"Thromboxane signalling through TP receptor","_row":"REACT_20647"} {"Pathway":"REACT_25004","Pathway_name":"Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits","_row":"REACT_25004"} {"Pathway":"REACT_264034","Pathway_name":"disassembly of the destruction complex and recruitment of AXIN to the membrane","_row":"REACT_264034"} {"Pathway":"REACT_264384","Pathway_name":"WNT mediated activation of DVL","_row":"REACT_264384"} {"Pathway":"REACT_264596","Pathway_name":"TCF dependent signaling in response to WNT","_row":"REACT_264596"} {"Pathway":"REACT_264276","Pathway_name":"negative regulation of TCF-dependent signaling by DVL-interacting proteins","_row":"REACT_264276"} {"Pathway":"REACT_264199","Pathway_name":"PCP/CE pathway","_row":"REACT_264199"} {"Pathway":"REACT_118607","Pathway_name":"Signaling by Hippo","_row":"REACT_118607"} {"Pathway":"REACT_263890","Pathway_name":"WNT5A-dependent internalization of FZD4","_row":"REACT_263890"} {"Pathway":"REACT_75899","Pathway_name":"TWIK-releated acid-sensitive K+ channel (TASK)","_row":"REACT_75899"} {"Pathway":"REACT_150203","Pathway_name":"IRS-related events triggered by IGF1R","_row":"REACT_150203"} {"Pathway":"REACT_9417","Pathway_name":"Signaling by EGFR","_row":"REACT_9417"} {"Pathway":"REACT_264198","Pathway_name":"EPH-ephrin mediated repulsion of cells","_row":"REACT_264198"} {"Pathway":"REACT_118572","Pathway_name":"Degradation of the extracellular matrix","_row":"REACT_118572"} {"Pathway":"REACT_163862","Pathway_name":"Cobalamin (Cbl, vitamin B12) transport and metabolism","_row":"REACT_163862"} {"Pathway":"REACT_150149","Pathway_name":"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)","_row":"REACT_150149"} {"Pathway":"REACT_268728","Pathway_name":"PKMTs methylate histone lysines","_row":"REACT_268728"} {"Pathway":"REACT_18426","Pathway_name":"Opsins","_row":"REACT_18426"} {"Pathway":"REACT_607","Pathway_name":"Activation of caspases through apoptosome-mediated cleavage","_row":"REACT_607"} {"Pathway":"REACT_89","Pathway_name":"Formation of apoptosome","_row":"REACT_89"} {"Pathway":"REACT_150352","Pathway_name":"Synthesis of IP2, IP, and Ins in the cytosol","_row":"REACT_150352"} {"Pathway":"REACT_264618","Pathway_name":"Uptake and function of anthrax toxins","_row":"REACT_264618"} {"Pathway":"REACT_21368","Pathway_name":"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1","_row":"REACT_21368"} {"Pathway":"REACT_17017","Pathway_name":"Beta-oxidation of pristanoyl-CoA","_row":"REACT_17017"} {"Pathway":"REACT_121147","Pathway_name":"alpha-linolenic acid (ALA) metabolism","_row":"REACT_121147"} {"Pathway":"REACT_11041","Pathway_name":"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol","_row":"REACT_11041"} {"Pathway":"REACT_17062","Pathway_name":"Beta-oxidation of very long chain fatty acids","_row":"REACT_17062"} {"Pathway":"REACT_121000","Pathway_name":"Synthesis of PI","_row":"REACT_121000"} {"Pathway":"REACT_11066","Pathway_name":"snRNP Assembly","_row":"REACT_11066"} {"Pathway":"REACT_7974","Pathway_name":"Telomere Extension By Telomerase","_row":"REACT_7974"} {"Pathway":"REACT_160156","Pathway_name":"The canonical retinoid cycle in rods (twilight vision)","_row":"REACT_160156"} {"Pathway":"REACT_897","Pathway_name":"G2/M DNA damage checkpoint","_row":"REACT_897"} {"Pathway":"REACT_407","Pathway_name":"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex","_row":"REACT_407"} {"Pathway":"REACT_163919","Pathway_name":"Inactivation, recovery and regulation of the phototransduction cascade","_row":"REACT_163919"} {"Pathway":"REACT_22272","Pathway_name":"Signal transduction by L1","_row":"REACT_22272"} {"Pathway":"REACT_19236","Pathway_name":"Sema3A PAK dependent Axon repulsion","_row":"REACT_19236"} {"Pathway":"REACT_12473","Pathway_name":"Neurophilin interactions with VEGF and VEGFR","_row":"REACT_12473"} {"Pathway":"REACT_19279","Pathway_name":"SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion","_row":"REACT_19279"} {"Pathway":"REACT_15293","Pathway_name":"Dopamine Neurotransmitter Release Cycle","_row":"REACT_15293"} {"Pathway":"REACT_15309","Pathway_name":"Acetylcholine Neurotransmitter Release Cycle","_row":"REACT_15309"} {"Pathway":"REACT_15418","Pathway_name":"Norepinephrine Neurotransmitter Release Cycle","_row":"REACT_15418"} {"Pathway":"REACT_15425","Pathway_name":"Serotonin Neurotransmitter Release Cycle","_row":"REACT_15425"} {"Pathway":"REACT_118823","Pathway_name":"Cytosolic sensors of pathogen-associated DNA ","_row":"REACT_118823"} {"Pathway":"REACT_756","Pathway_name":"RNA Polymerase III Chain Elongation","_row":"REACT_756"} {"Pathway":"REACT_16983","Pathway_name":"Amine ligand-binding receptors","_row":"REACT_16983"} {"Pathway":"REACT_23947","Pathway_name":"GABA synthesis, release, reuptake and degradation","_row":"REACT_23947"} {"Pathway":"REACT_13638","Pathway_name":"NRAGE signals death through JNK","_row":"REACT_13638"} {"Pathway":"REACT_20546","Pathway_name":"Ras activation uopn Ca2+ infux through NMDA receptor","_row":"REACT_20546"} {"Pathway":"REACT_17003","Pathway_name":"Alpha-oxidation of phytanate","_row":"REACT_17003"} {"Pathway":"REACT_268256","Pathway_name":"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)","_row":"REACT_268256"} {"Pathway":"REACT_19193","Pathway_name":"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion","_row":"REACT_19193"} {"Pathway":"REACT_23824","Pathway_name":"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)","_row":"REACT_23824"} {"Pathway":"REACT_75777","Pathway_name":"The AIM2 inflammasome","_row":"REACT_75777"} {"Pathway":"REACT_6926","Pathway_name":"Glutathione conjugation","_row":"REACT_6926"} {"Pathway":"REACT_264383","Pathway_name":"negative regulation of TCF-dependent signaling by WNT ligand antagonists","_row":"REACT_264383"} {"Pathway":"REACT_355021","Pathway_name":"RHO GTPases Activate Rhotekin and Rhophilins","_row":"REACT_355021"} {"Pathway":"REACT_13696","Pathway_name":"NF-kB is activated and signals survival","_row":"REACT_13696"} {"Pathway":"REACT_13415","Pathway_name":"p75NTR recruits signalling complexes","_row":"REACT_13415"} {"Pathway":"REACT_118563","Pathway_name":"RIP-mediated NFkB activation via ZBP1","_row":"REACT_118563"} {"Pathway":"REACT_24918","Pathway_name":"IRAK1 recruits IKK complex","_row":"REACT_24918"} {"Pathway":"REACT_355196","Pathway_name":"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)","_row":"REACT_355196"} {"Pathway":"REACT_355183","Pathway_name":"IKBKB deficiency causes SCID","_row":"REACT_355183"} {"Pathway":"REACT_75776","Pathway_name":"NOD1/2 Signaling Pathway","_row":"REACT_75776"} {"Pathway":"REACT_355226","Pathway_name":"IkBA variant leads to EDA-ID","_row":"REACT_355226"} {"Pathway":"REACT_22442","Pathway_name":"Interleukin-1 signaling","_row":"REACT_22442"} {"Pathway":"REACT_24969","Pathway_name":"TRAF6 mediated NF-kB activation","_row":"REACT_24969"} {"Pathway":"REACT_25039","Pathway_name":"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10","_row":"REACT_25039"} {"Pathway":"REACT_25354","Pathway_name":"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation","_row":"REACT_25354"} {"Pathway":"REACT_21281","Pathway_name":"TAK1 activates NFkB by phosphorylation and activation of IKKs complex","_row":"REACT_21281"} {"Pathway":"REACT_118595","Pathway_name":"Mitochondrial protein import","_row":"REACT_118595"} {"Pathway":"REACT_264245","Pathway_name":"HATs acetylate histones","_row":"REACT_264245"} {"Pathway":"REACT_25359","Pathway_name":"RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways","_row":"REACT_25359"} {"Pathway":"REACT_25271","Pathway_name":"Negative regulators of RIG-I/MDA5 signaling","_row":"REACT_25271"} {"Pathway":"REACT_355250","Pathway_name":"Termination of translesion DNA synthesis","_row":"REACT_355250"} {"Pathway":"REACT_163942","Pathway_name":"Syndecan interactions","_row":"REACT_163942"} {"Pathway":"REACT_120906","Pathway_name":"Synthesis of PA","_row":"REACT_120906"} {"Pathway":"REACT_121280","Pathway_name":"Synthesis of PG","_row":"REACT_121280"} {"Pathway":"REACT_264548","Pathway_name":"EPHA-mediated growth cone collapse","_row":"REACT_264548"} {"Pathway":"REACT_355192","Pathway_name":"RHO GTPases Activate ROCKs","_row":"REACT_355192"} {"Pathway":"REACT_355347","Pathway_name":"RHO GTPases activate PAKs","_row":"REACT_355347"} {"Pathway":"REACT_20558","Pathway_name":"Smooth Muscle Contraction","_row":"REACT_20558"} {"Pathway":"REACT_355542","Pathway_name":"RHO GTPases activate PKNs","_row":"REACT_355542"} {"Pathway":"REACT_19277","Pathway_name":"Sema4D induced cell migration and growth-cone collapse","_row":"REACT_19277"} {"Pathway":"REACT_12484","Pathway_name":"EGFR downregulation","_row":"REACT_12484"} {"Pathway":"REACT_11053","Pathway_name":"Synthesis of bile acids and bile salts via 24-hydroxycholesterol","_row":"REACT_11053"} {"Pathway":"REACT_1857","Pathway_name":"Cyclin A/B1 associated events during G2/M transition","_row":"REACT_1857"} {"Pathway":"REACT_6190","Pathway_name":"Rev-mediated nuclear export of HIV RNA","_row":"REACT_6190"} {"Pathway":"REACT_120727","Pathway_name":"Downregulation of TGF-beta receptor signaling","_row":"REACT_120727"} {"Pathway":"REACT_25218","Pathway_name":"HuR stabilizes mRNA","_row":"REACT_25218"} {"Pathway":"REACT_6179","Pathway_name":"NEP/NS2 Interacts with the Cellular Export Machinery","_row":"REACT_6179"} {"Pathway":"REACT_23765","Pathway_name":"Reduction of cytosolic Ca++ levels","_row":"REACT_23765"} {"Pathway":"REACT_22266","Pathway_name":"Interaction between L1 and Ankyrins","_row":"REACT_22266"} {"Pathway":"REACT_18334","Pathway_name":"NCAM signaling for neurite out-growth","_row":"REACT_18334"} {"Pathway":"REACT_19200","Pathway_name":"Other semaphorin interactions","_row":"REACT_19200"} {"Pathway":"REACT_263961","Pathway_name":"HDMs demethylate histones","_row":"REACT_263961"} {"Pathway":"REACT_1776","Pathway_name":"Purine ribonucleoside monophosphate biosynthesis","_row":"REACT_1776"} {"Pathway":"REACT_355468","Pathway_name":"Constitutive Signaling by AKT1 E17K in 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{"Pathway":"REACT_121141","Pathway_name":"Signaling by FGFR1 fusion mutants","_row":"REACT_121141"} {"Pathway":"REACT_263992","Pathway_name":"APC truncation mutants have impaired AXIN binding","_row":"REACT_263992"} {"Pathway":"REACT_264092","Pathway_name":"misspliced GSK3beta mutants stabilize beta-catenin","_row":"REACT_264092"} {"Pathway":"REACT_264127","Pathway_name":"T41 mutants of beta-catenin aren't phosphorylated","_row":"REACT_264127"} {"Pathway":"REACT_264030","Pathway_name":"AXIN missense mutants destabilize the destruction complex","_row":"REACT_264030"} {"Pathway":"REACT_264295","Pathway_name":"S45 mutants of beta-catenin aren't phosphorylated","_row":"REACT_264295"} {"Pathway":"REACT_264636","Pathway_name":"S37 mutants of beta-catenin aren't phosphorylated","_row":"REACT_264636"} {"Pathway":"REACT_264581","Pathway_name":"S33 mutants of beta-catenin aren't phosphorylated","_row":"REACT_264581"} {"Pathway":"REACT_11065","Pathway_name":"Beta-catenin phosphorylation cascade","_row":"REACT_11065"} {"Pathway":"REACT_263893","Pathway_name":"truncations of AMER1 destabilize the destruction complex","_row":"REACT_263893"} {"Pathway":"REACT_264068","Pathway_name":"EPH-Ephrin signaling","_row":"REACT_264068"} {"Pathway":"REACT_16936","Pathway_name":"Prefoldin mediated transfer of substrate to CCT/TriC","_row":"REACT_16936"} {"Pathway":"REACT_916","Pathway_name":"Tryptophan catabolism","_row":"REACT_916"} {"Pathway":"REACT_169262","Pathway_name":"Laminin interactions","_row":"REACT_169262"} {"Pathway":"REACT_75822","Pathway_name":"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)","_row":"REACT_75822"} {"Pathway":"REACT_268133","Pathway_name":"Mitochondrial translation elongation","_row":"REACT_268133"} {"Pathway":"REACT_267634","Pathway_name":"Mitochondrial translation initiation","_row":"REACT_267634"} {"Pathway":"REACT_268261","Pathway_name":"Mitochondrial translation termination","_row":"REACT_268261"} {"Pathway":"REACT_20506","Pathway_name":"Na+/Cl- dependent neurotransmitter transporters","_row":"REACT_20506"} {"Pathway":"REACT_13583","Pathway_name":"Neurotransmitter Clearance In The Synaptic Cleft","_row":"REACT_13583"} {"Pathway":"REACT_22357","Pathway_name":"Organic cation transport","_row":"REACT_22357"} {"Pathway":"REACT_120801","Pathway_name":"Abacavir transmembrane transport","_row":"REACT_120801"} {"Pathway":"REACT_115897","Pathway_name":"Beta defensins","_row":"REACT_115897"} {"Pathway":"REACT_115846","Pathway_name":"Defensins","_row":"REACT_115846"} {"Pathway":"REACT_25299","Pathway_name":"DSCAM interactions","_row":"REACT_25299"} {"Pathway":"REACT_12065","Pathway_name":"p38MAPK events","_row":"REACT_12065"} {"Pathway":"REACT_16969","Pathway_name":"Striated Muscle Contraction","_row":"REACT_16969"} {"Pathway":"REACT_18410","Pathway_name":"Fanconi Anemia pathway","_row":"REACT_18410"} {"Pathway":"REACT_150422","Pathway_name":"Synthesis of 15-eicosatetraenoic acid derivatives","_row":"REACT_150422"} {"Pathway":"REACT_22423","Pathway_name":"Synthesis of GDP-mannose","_row":"REACT_22423"} {"Pathway":"REACT_25300","Pathway_name":"Ion channel transport","_row":"REACT_25300"} {"Pathway":"REACT_121256","Pathway_name":"Phagosomal maturation (early endosomal stage)","_row":"REACT_121256"} {"Pathway":"REACT_25283","Pathway_name":"Transferrin endocytosis and recycling","_row":"REACT_25283"} {"Pathway":"REACT_1109","Pathway_name":"Insulin receptor recycling","_row":"REACT_1109"} {"Pathway":"REACT_150312","Pathway_name":"Synthesis of IP3 and IP4 in the cytosol","_row":"REACT_150312"} {"Pathway":"REACT_13695","Pathway_name":"p75NTR negatively regulates cell cycle via SC1","_row":"REACT_13695"} {"Pathway":"REACT_118789","Pathway_name":"NR1D1 (REV-ERBA) represses gene expression","_row":"REACT_118789"} {"Pathway":"REACT_118780","Pathway_name":"NOTCH1 Intracellular Domain Regulates Transcription","_row":"REACT_118780"} {"Pathway":"REACT_19241","Pathway_name":"Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)","_row":"REACT_19241"} {"Pathway":"REACT_197","Pathway_name":"Branched-chain amino acid catabolism","_row":"REACT_197"} {"Pathway":"REACT_268530","Pathway_name":"Transcriptional regulation by small RNAs","_row":"REACT_268530"} {"Pathway":"REACT_20642","Pathway_name":"CREB phosphorylation through the activation of CaMKII","_row":"REACT_20642"} {"Pathway":"REACT_20594","Pathway_name":"Unblocking of NMDA receptor, glutamate binding and activation","_row":"REACT_20594"} {"Pathway":"REACT_20515","Pathway_name":"Proton-coupled monocarboxylate transport","_row":"REACT_20515"} {"Pathway":"REACT_12560","Pathway_name":"Basigin interactions","_row":"REACT_12560"} {"Pathway":"REACT_20547","Pathway_name":"Metal ion SLC transporters","_row":"REACT_20547"} {"Pathway":"REACT_15480","Pathway_name":"ABC-family proteins mediated transport","_row":"REACT_15480"} {"Pathway":"REACT_11042","Pathway_name":"Recycling of bile acids and salts","_row":"REACT_11042"} {"Pathway":"REACT_355217","Pathway_name":"TRAF3 deficiency - HSE","_row":"REACT_355217"} {"Pathway":"REACT_355281","Pathway_name":"TICAM1 deficiency - HSE","_row":"REACT_355281"} {"Pathway":"REACT_118632","Pathway_name":"Trafficking and processing of endosomal TLR","_row":"REACT_118632"} {"Pathway":"REACT_355056","Pathway_name":"UNC93B1 deficiency - HSE","_row":"REACT_355056"} {"Pathway":"REACT_6783","Pathway_name":"Toll Like Receptor 3 (TLR3) Cascade","_row":"REACT_6783"} {"Pathway":"REACT_355549","Pathway_name":"TLR3 deficiency - HSE","_row":"REACT_355549"} {"Pathway":"REACT_27271","Pathway_name":"Meiotic recombination","_row":"REACT_27271"} {"Pathway":"REACT_264366","Pathway_name":"Sialic acid metabolism","_row":"REACT_264366"} {"Pathway":"REACT_1008","Pathway_name":"Glycogen breakdown (glycogenolysis)","_row":"REACT_1008"} {"Pathway":"REACT_169208","Pathway_name":"Glycogen synthesis","_row":"REACT_169208"} {"Pathway":"REACT_264430","Pathway_name":"Myoclonic epilepsy of Lafora","_row":"REACT_264430"} {"Pathway":"REACT_355557","Pathway_name":"Lysosomal glycogen catabolism","_row":"REACT_355557"} {"Pathway":"REACT_121324","Pathway_name":"Acyl chain remodelling of PG","_row":"REACT_121324"} {"Pathway":"REACT_121369","Pathway_name":"Acyl chain remodelling of PE","_row":"REACT_121369"} {"Pathway":"REACT_120722","Pathway_name":"Acyl chain remodelling of PI","_row":"REACT_120722"} {"Pathway":"REACT_120829","Pathway_name":"Acyl chain remodelling of PC","_row":"REACT_120829"} {"Pathway":"REACT_121384","Pathway_name":"Acyl chain remodelling of PS","_row":"REACT_121384"} {"Pathway":"REACT_147797","Pathway_name":"Regulation of cholesterol biosynthesis by SREBP (SREBF)","_row":"REACT_147797"} {"Pathway":"REACT_7991","Pathway_name":"Vpr-mediated nuclear import of PICs","_row":"REACT_7991"} {"Pathway":"REACT_9395","Pathway_name":"Nuclear import of Rev protein","_row":"REACT_9395"} {"Pathway":"REACT_6354","Pathway_name":"Viral Messenger RNA Synthesis","_row":"REACT_6354"} {"Pathway":"REACT_6804","Pathway_name":"Regulation of Glucokinase by Glucokinase Regulatory Protein","_row":"REACT_6804"} {"Pathway":"REACT_163931","Pathway_name":"Nuclear Pore Complex (NPC) Disassembly","_row":"REACT_163931"} {"Pathway":"REACT_264487","Pathway_name":"Regulation of HSF1-mediated heat shock response","_row":"REACT_264487"} {"Pathway":"REACT_267790","Pathway_name":"PIWI-interacting RNA (piRNA) biogenesis","_row":"REACT_267790"} {"Pathway":"REACT_1941","Pathway_name":"Formation of transcription-coupled NER (TC-NER) repair complex","_row":"REACT_1941"} {"Pathway":"REACT_2222","Pathway_name":"Dual incision reaction in TC-NER","_row":"REACT_2222"} {"Pathway":"REACT_263856","Pathway_name":"Transcriptional regulation of pluripotent stem cells","_row":"REACT_263856"} {"Pathway":"REACT_264617","Pathway_name":"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation","_row":"REACT_264617"} {"Pathway":"REACT_125","Pathway_name":"Processing of Capped Intron-Containing Pre-mRNA","_row":"REACT_125"} {"Pathway":"REACT_1753","Pathway_name":"mRNA Splicing - Minor Pathway","_row":"REACT_1753"} {"Pathway":"REACT_467","Pathway_name":"mRNA Splicing - Major Pathway","_row":"REACT_467"} {"Pathway":"REACT_12417","Pathway_name":"MicroRNA (miRNA) biogenesis","_row":"REACT_12417"} {"Pathway":"REACT_1628","Pathway_name":"Transcription-coupled NER (TC-NER)","_row":"REACT_1628"} {"Pathway":"REACT_355584","Pathway_name":"FRS-mediated FGFR1 signaling","_row":"REACT_355584"} {"Pathway":"REACT_355218","Pathway_name":"Negative regulation of FGFR1 signaling","_row":"REACT_355218"} {"Pathway":"REACT_355227","Pathway_name":"Negative regulation of FGFR2 signaling","_row":"REACT_355227"} {"Pathway":"REACT_355450","Pathway_name":"PI-3K cascade:FGFR2","_row":"REACT_355450"} {"Pathway":"REACT_9416","Pathway_name":"FGFR2b ligand binding and activation","_row":"REACT_9416"} {"Pathway":"REACT_9400","Pathway_name":"FGFR1b ligand binding and activation","_row":"REACT_9400"} {"Pathway":"REACT_355146","Pathway_name":"Phospholipase C-mediated cascade; FGFR2","_row":"REACT_355146"} {"Pathway":"REACT_355552","Pathway_name":"PI-3K cascade:FGFR1","_row":"REACT_355552"} {"Pathway":"REACT_355194","Pathway_name":"SHC-mediated cascade:FGFR1","_row":"REACT_355194"} {"Pathway":"REACT_355225","Pathway_name":"SHC-mediated cascade:FGFR2","_row":"REACT_355225"} {"Pathway":"REACT_355202","Pathway_name":"Signaling by FGFR4 mutants","_row":"REACT_355202"} {"Pathway":"REACT_110235","Pathway_name":"Phospholipase C-mediated cascade: FGFR1","_row":"REACT_110235"} {"Pathway":"REACT_355511","Pathway_name":"Signaling by FGFR2 mutants","_row":"REACT_355511"} {"Pathway":"REACT_355069","Pathway_name":"FRS-mediated FGFR2 signaling","_row":"REACT_355069"} {"Pathway":"REACT_120863","Pathway_name":"Activated point mutants of FGFR2","_row":"REACT_120863"} {"Pathway":"REACT_355367","Pathway_name":"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway","_row":"REACT_355367"} {"Pathway":"REACT_1064","Pathway_name":"Displacement of DNA glycosylase by APEX1","_row":"REACT_1064"} {"Pathway":"REACT_2176","Pathway_name":"Recognition and association of DNA glycosylase with site containing an affected purine","_row":"REACT_2176"} {"Pathway":"REACT_1729","Pathway_name":"Cleavage of the damaged purine","_row":"REACT_1729"} {"Pathway":"REACT_2156","Pathway_name":"Cleavage of the damaged pyrimidine ","_row":"REACT_2156"} {"Pathway":"REACT_702","Pathway_name":"Recognition and association of DNA glycosylase with site containing an affected pyrimidine","_row":"REACT_702"} {"Pathway":"REACT_13450","Pathway_name":"Vitamins","_row":"REACT_13450"} {"Pathway":"REACT_268633","Pathway_name":"Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)","_row":"REACT_268633"} {"Pathway":"REACT_13523","Pathway_name":"Vitamin D (calciferol) metabolism","_row":"REACT_13523"} {"Pathway":"REACT_790","Pathway_name":"Activation of PKB","_row":"REACT_790"} {"Pathway":"REACT_19405","Pathway_name":"CTLA4 inhibitory signaling","_row":"REACT_19405"} {"Pathway":"REACT_15523","Pathway_name":"Integrin alphaIIb beta3 signaling","_row":"REACT_15523"} {"Pathway":"REACT_264273","Pathway_name":"VEGFR2 mediated cell proliferation","_row":"REACT_264273"} {"Pathway":"REACT_20510","Pathway_name":"RSK activation","_row":"REACT_20510"} {"Pathway":"REACT_263991","Pathway_name":"VEGFR2 mediated vascular permeability","_row":"REACT_263991"} {"Pathway":"REACT_75795","Pathway_name":"Antigen Presentation: Folding, assembly and peptide loading of class I MHC","_row":"REACT_75795"} {"Pathway":"REACT_75808","Pathway_name":"The NLRP3 inflammasome","_row":"REACT_75808"} {"Pathway":"REACT_75896","Pathway_name":"Ca2+ activated K+ channels","_row":"REACT_75896"} {"Pathway":"REACT_263919","Pathway_name":"TET1,2,3 and TDG demethylate DNA","_row":"REACT_263919"} {"Pathway":"REACT_19266","Pathway_name":"Sema4D mediated inhibition of cell attachment and migration","_row":"REACT_19266"} {"Pathway":"REACT_264541","Pathway_name":"SIRT1 negatively regulates rRNA Expression","_row":"REACT_264541"} {"Pathway":"REACT_25085","Pathway_name":"N-Glycan antennae elongation","_row":"REACT_25085"} {"Pathway":"REACT_268561","Pathway_name":"RA biosynthesis pathway","_row":"REACT_268561"} {"Pathway":"REACT_115789","Pathway_name":"Serine biosynthesis","_row":"REACT_115789"} {"Pathway":"REACT_27215","Pathway_name":"MyD88 cascade initiated on plasma membrane","_row":"REACT_27215"} {"Pathway":"REACT_25018","Pathway_name":"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation","_row":"REACT_25018"} {"Pathway":"REACT_25380","Pathway_name":"IRAK2 mediated activation of TAK1 complex","_row":"REACT_25380"} {"Pathway":"REACT_25222","Pathway_name":"MyD88 dependent cascade initiated on endosome","_row":"REACT_25222"} {"Pathway":"REACT_25024","Pathway_name":"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation","_row":"REACT_25024"} {"Pathway":"REACT_21399","Pathway_name":"activated TAK1 mediates p38 MAPK activation","_row":"REACT_21399"} {"Pathway":"REACT_264352","Pathway_name":"PRC2 methylates histones and DNA","_row":"REACT_264352"} {"Pathway":"REACT_14828","Pathway_name":"Class A/1 (Rhodopsin-like receptors)","_row":"REACT_14828"} {"Pathway":"REACT_6840","Pathway_name":"Transport and synthesis of PAPS","_row":"REACT_6840"} {"Pathway":"REACT_22237","Pathway_name":"Netrin-1 signaling","_row":"REACT_22237"} {"Pathway":"REACT_1002","Pathway_name":"Proline catabolism","_row":"REACT_1002"} {"Pathway":"REACT_9472","Pathway_name":"Digestion of dietary carbohydrate","_row":"REACT_9472"} {"Pathway":"REACT_121120","Pathway_name":"Keratan sulfate biosynthesis","_row":"REACT_121120"} {"Pathway":"REACT_115606","Pathway_name":"O-linked glycosylation of mucins","_row":"REACT_115606"} {"Pathway":"REACT_1830","Pathway_name":"Attachment of GPI anchor to uPAR","_row":"REACT_1830"} {"Pathway":"REACT_22128","Pathway_name":"Ligand-independent caspase activation via DCC","_row":"REACT_22128"} {"Pathway":"REACT_19342","Pathway_name":"Inactivation of Cdc42 and Rac","_row":"REACT_19342"} {"Pathway":"REACT_1946","Pathway_name":"PKA activation in glucagon signalling","_row":"REACT_1946"} {"Pathway":"REACT_268323","Pathway_name":"Hedgehog 'off' state","_row":"REACT_268323"} {"Pathway":"REACT_15530","Pathway_name":"PKA activation","_row":"REACT_15530"} {"Pathway":"REACT_15312","Pathway_name":"Adenylate cyclase activating pathway","_row":"REACT_15312"} {"Pathway":"REACT_1665","Pathway_name":"Glucagon signaling in metabolic regulation","_row":"REACT_1665"} {"Pathway":"REACT_24987","Pathway_name":"GABA A receptor activation","_row":"REACT_24987"} {"Pathway":"REACT_150188","Pathway_name":"Synthesis of pyrophosphates in the cytosol","_row":"REACT_150188"} {"Pathway":"REACT_13650","Pathway_name":"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells","_row":"REACT_13650"} {"Pathway":"REACT_9413","Pathway_name":"FGFR2c ligand binding and activation","_row":"REACT_9413"} {"Pathway":"REACT_9452","Pathway_name":"FGFR4 ligand binding and activation","_row":"REACT_9452"} {"Pathway":"REACT_355212","Pathway_name":"FRS-mediated FGFR3 signaling","_row":"REACT_355212"} {"Pathway":"REACT_121337","Pathway_name":"Signaling by activated point mutants of FGFR3","_row":"REACT_121337"} {"Pathway":"REACT_355197","Pathway_name":"SHC-mediated cascade:FGFR3","_row":"REACT_355197"} {"Pathway":"REACT_355313","Pathway_name":"Signaling by FGFR3 mutants","_row":"REACT_355313"} {"Pathway":"REACT_355304","Pathway_name":"PI-3K cascade:FGFR4","_row":"REACT_355304"} {"Pathway":"REACT_9510","Pathway_name":"FGFR3c ligand binding and activation","_row":"REACT_9510"} {"Pathway":"REACT_355514","Pathway_name":"Phospholipase C-mediated cascade; FGFR3","_row":"REACT_355514"} {"Pathway":"REACT_121249","Pathway_name":"FGFR3 mutant receptor activation","_row":"REACT_121249"} {"Pathway":"REACT_355216","Pathway_name":"Phospholipase C-mediated cascade; FGFR4","_row":"REACT_355216"} {"Pathway":"REACT_355588","Pathway_name":"Negative regulation of FGFR4 signaling","_row":"REACT_355588"} {"Pathway":"REACT_355159","Pathway_name":"SHC-mediated cascade:FGFR4","_row":"REACT_355159"} {"Pathway":"REACT_355160","Pathway_name":"PI-3K cascade:FGFR3","_row":"REACT_355160"} {"Pathway":"REACT_355580","Pathway_name":"FRS2-mediated FGFR4 signaling","_row":"REACT_355580"} {"Pathway":"REACT_355144","Pathway_name":"Negative regulation of FGFR3 signaling","_row":"REACT_355144"} {"Pathway":"REACT_268573","Pathway_name":"Ligand-receptor interactions","_row":"REACT_268573"} {"Pathway":"REACT_15306","Pathway_name":"Cytosolic tRNA aminoacylation","_row":"REACT_15306"} {"Pathway":"REACT_75770","Pathway_name":"Voltage gated Potassium channels","_row":"REACT_75770"} {"Pathway":"REACT_18348","Pathway_name":"ATF6-alpha activates chaperones","_row":"REACT_18348"} {"Pathway":"REACT_19189","Pathway_name":"Synthesis, secretion, and deacylation of Ghrelin","_row":"REACT_19189"} {"Pathway":"REACT_163933","Pathway_name":"Interaction With The Zona Pellucida","_row":"REACT_163933"} {"Pathway":"REACT_1650","Pathway_name":"Activation of BIM and translocation to mitochondria ","_row":"REACT_1650"} {"Pathway":"REACT_330","Pathway_name":"BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members","_row":"REACT_330"} {"Pathway":"REACT_12442","Pathway_name":"AKT phosphorylates targets in the nucleus","_row":"REACT_12442"} {"Pathway":"REACT_16942","Pathway_name":"Hormone ligand-binding receptors","_row":"REACT_16942"} {"Pathway":"REACT_121123","Pathway_name":"Reversible hydration of carbon dioxide","_row":"REACT_121123"} {"Pathway":"REACT_111080","Pathway_name":"Spry regulation of FGF signaling","_row":"REACT_111080"} {"Pathway":"REACT_19226","Pathway_name":"Activation of Rac","_row":"REACT_19226"} {"Pathway":"REACT_1786","Pathway_name":"Phenylalanine and tyrosine catabolism","_row":"REACT_1786"} {"Pathway":"REACT_264544","Pathway_name":"Activation of PPARGC1A (PGC-1alpha) by phosphorylation","_row":"REACT_264544"} {"Pathway":"REACT_21285","Pathway_name":"Regulation of AMPK activity via LKB1","_row":"REACT_21285"} {"Pathway":"REACT_21393","Pathway_name":"Regulation of Rheb GTPase activity by AMPK","_row":"REACT_21393"} {"Pathway":"REACT_1988","Pathway_name":"AMPK inhibits chREBP transcriptional activation activity","_row":"REACT_1988"} {"Pathway":"REACT_11103","Pathway_name":"Nef mediated downregulation of MHC class I complex cell surface expression","_row":"REACT_11103"} {"Pathway":"REACT_150182","Pathway_name":"MASTL Facilitates Mitotic Progression","_row":"REACT_150182"} {"Pathway":"REACT_387","Pathway_name":"Cleavage of Growing Transcript in the Termination Region ","_row":"REACT_387"} {"Pathway":"REACT_1096","Pathway_name":"Processing of Intronless Pre-mRNAs","_row":"REACT_1096"} {"Pathway":"REACT_1849","Pathway_name":"mRNA 3'-end processing","_row":"REACT_1849"} {"Pathway":"REACT_120996","Pathway_name":"Hyaluronan uptake and degradation","_row":"REACT_120996"} {"Pathway":"REACT_212","Pathway_name":"Glucose transport","_row":"REACT_212"} {"Pathway":"REACT_1597","Pathway_name":"Transport of Mature mRNA derived from an Intron-Containing Transcript","_row":"REACT_1597"} {"Pathway":"REACT_188329","Pathway_name":"CLEC7A (Dectin-1) induces NFAT activation","_row":"REACT_188329"} {"Pathway":"REACT_111064","Pathway_name":"DAG and IP3 signaling","_row":"REACT_111064"} {"Pathway":"REACT_150206","Pathway_name":"Crosslinking of collagen fibrils","_row":"REACT_150206"} {"Pathway":"REACT_150268","Pathway_name":"Anchoring fibril formation","_row":"REACT_150268"} {"Pathway":"REACT_13541","Pathway_name":"Caspase-mediated cleavage of cytoskeletal proteins","_row":"REACT_13541"} {"Pathway":"REACT_1321","Pathway_name":"E2F-enabled inhibition of pre-replication complex formation","_row":"REACT_1321"} {"Pathway":"REACT_567","Pathway_name":"Assembly of the ORC complex at the origin of replication","_row":"REACT_567"} {"Pathway":"REACT_207","Pathway_name":"Removal of licensing factors from origins","_row":"REACT_207"} {"Pathway":"REACT_2243","Pathway_name":"Assembly of the pre-replicative complex","_row":"REACT_2243"} {"Pathway":"REACT_12583","Pathway_name":"VEGF binds to VEGFR leading to receptor dimerization","_row":"REACT_12583"} {"Pathway":"REACT_12380","Pathway_name":"VEGF ligand-receptor interactions","_row":"REACT_12380"} {"Pathway":"REACT_268148","Pathway_name":"ARL13B-mediated ciliary trafficking of INPP5E","_row":"REACT_268148"} {"Pathway":"REACT_150266","Pathway_name":"Establishment of Sister Chromatid Cohesion","_row":"REACT_150266"} {"Pathway":"REACT_75792","Pathway_name":"Meiotic synapsis","_row":"REACT_75792"} {"Pathway":"REACT_150421","Pathway_name":"Cohesin Loading onto Chromatin","_row":"REACT_150421"} {"Pathway":"REACT_9515","Pathway_name":"FGFR1c ligand binding and activation","_row":"REACT_9515"} {"Pathway":"REACT_121153","Pathway_name":"Signaling by activated point mutants of FGFR1","_row":"REACT_121153"} {"Pathway":"REACT_9508","Pathway_name":"FGFR3b ligand binding and activation","_row":"REACT_9508"} {"Pathway":"REACT_355221","Pathway_name":"Signaling by FGFR1 mutants","_row":"REACT_355221"} {"Pathway":"REACT_20625","Pathway_name":"CREB phosphorylation through the activation of Adenylate Cyclase","_row":"REACT_20625"} {"Pathway":"REACT_355391","Pathway_name":"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3","_row":"REACT_355391"} {"Pathway":"REACT_12447","Pathway_name":"Negative regulation of the PI3K/AKT network","_row":"REACT_12447"} {"Pathway":"REACT_264580","Pathway_name":"regulation of FZD by ubiquitination","_row":"REACT_264580"} {"Pathway":"REACT_264378","Pathway_name":"RNF mutants show enhanced WNT signaling and proliferation","_row":"REACT_264378"} {"Pathway":"REACT_18307","Pathway_name":"Trafficking of AMPA receptors","_row":"REACT_18307"} {"Pathway":"REACT_13673","Pathway_name":"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells","_row":"REACT_13673"} {"Pathway":"REACT_121100","Pathway_name":"Linoleic acid (LA) metabolism","_row":"REACT_121100"} {"Pathway":"REACT_22329","Pathway_name":"NrCAM interactions","_row":"REACT_22329"} {"Pathway":"REACT_25396","Pathway_name":"Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2","_row":"REACT_25396"} {"Pathway":"REACT_169132","Pathway_name":"Defective CUBN causes hereditary megaloblastic anemia 1","_row":"REACT_169132"} {"Pathway":"REACT_169280","Pathway_name":"Defective AMN causes hereditary megaloblastic anemia 1","_row":"REACT_169280"} {"Pathway":"REACT_13621","Pathway_name":"HDL-mediated lipid transport","_row":"REACT_13621"} {"Pathway":"REACT_6905","Pathway_name":"Interactions of Tat with host cellular proteins","_row":"REACT_6905"} {"Pathway":"REACT_9061","Pathway_name":"Toll Like Receptor 5 (TLR5) Cascade","_row":"REACT_9061"} {"Pathway":"REACT_355363","Pathway_name":"MyD88 deficiency (TLR5)","_row":"REACT_355363"} {"Pathway":"REACT_355387","Pathway_name":"IRAK4 deficiency (TLR5)","_row":"REACT_355387"} {"Pathway":"REACT_8005","Pathway_name":"Toll Like Receptor TLR1:TLR2 Cascade","_row":"REACT_8005"} {"Pathway":"REACT_8006","Pathway_name":"Toll Like Receptor TLR6:TLR2 Cascade","_row":"REACT_8006"} {"Pathway":"REACT_6784","Pathway_name":"Glucuronidation","_row":"REACT_6784"} {"Pathway":"REACT_8","Pathway_name":"Translesion synthesis by REV1","_row":"REACT_8"} {"Pathway":"REACT_355158","Pathway_name":"Translesion synthesis by POLK","_row":"REACT_355158"} {"Pathway":"REACT_355324","Pathway_name":"Translesion synthesis by POLI","_row":"REACT_355324"} {"Pathway":"REACT_1391","Pathway_name":"ERK1 activation","_row":"REACT_1391"} {"Pathway":"REACT_1183","Pathway_name":"ERK2 activation","_row":"REACT_1183"} {"Pathway":"REACT_115697","Pathway_name":"Prolactin receptor signaling","_row":"REACT_115697"} {"Pathway":"REACT_6737","Pathway_name":"Formation of the active cofactor, UDP-glucuronate","_row":"REACT_6737"} {"Pathway":"REACT_75775","Pathway_name":"ATP sensitive Potassium channels","_row":"REACT_75775"} {"Pathway":"REACT_19195","Pathway_name":"Adherens junctions interactions","_row":"REACT_19195"} {"Pathway":"REACT_19320","Pathway_name":"Sodium/Calcium exchangers","_row":"REACT_19320"} {"Pathway":"REACT_163932","Pathway_name":"Activation of the phototransduction cascade","_row":"REACT_163932"} {"Pathway":"REACT_121006","Pathway_name":"Acyl chain remodeling of CL","_row":"REACT_121006"} {"Pathway":"REACT_75862","Pathway_name":"HCN channels","_row":"REACT_75862"} {"Pathway":"REACT_2032","Pathway_name":"Synthesis of dolichyl-phosphate mannose","_row":"REACT_2032"} {"Pathway":"REACT_1100","Pathway_name":"Golgi Cisternae Pericentriolar Stack Reorganization","_row":"REACT_1100"} {"Pathway":"REACT_11117","Pathway_name":"Vitamin B1 (thiamin) metabolism","_row":"REACT_11117"} {"Pathway":"REACT_169185","Pathway_name":"DNA Damage/Telomere Stress Induced Senescence","_row":"REACT_169185"} {"Pathway":"REACT_7963","Pathway_name":"Packaging Of Telomere Ends","_row":"REACT_7963"} {"Pathway":"REACT_2232","Pathway_name":"RNA Polymerase I Promoter Opening","_row":"REACT_2232"} {"Pathway":"REACT_264303","Pathway_name":"Condensation of Prophase Chromosomes","_row":"REACT_264303"} {"Pathway":"REACT_268237","Pathway_name":"DNA methylation","_row":"REACT_268237"} {"Pathway":"REACT_18290","Pathway_name":"Calcitonin-like ligand receptors","_row":"REACT_18290"} {"Pathway":"REACT_116105","Pathway_name":"Glycosphingolipid metabolism","_row":"REACT_116105"} {"Pathway":"REACT_13806","Pathway_name":"Ceramide signalling","_row":"REACT_13806"} {"Pathway":"REACT_118713","Pathway_name":"YAP1- and WWTR1 (TAZ)-stimulated gene expression","_row":"REACT_118713"} {"Pathway":"REACT_118682","Pathway_name":"Activation of Matrix Metalloproteinases","_row":"REACT_118682"} {"Pathway":"REACT_111168","Pathway_name":"Endosomal/Vacuolar pathway","_row":"REACT_111168"} {"Pathway":"REACT_268444","Pathway_name":"Miscellaneous transport and binding events","_row":"REACT_268444"} {"Pathway":"REACT_1924","Pathway_name":"ATM mediated phosphorylation of repair proteins","_row":"REACT_1924"} {"Pathway":"REACT_1884","Pathway_name":"MRN complex relocalizes to nuclear foci","_row":"REACT_1884"} {"Pathway":"REACT_486","Pathway_name":"Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks","_row":"REACT_486"} {"Pathway":"REACT_268431","Pathway_name":"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)","_row":"REACT_268431"} {"Pathway":"REACT_121313","Pathway_name":"Keratan sulfate degradation","_row":"REACT_121313"} {"Pathway":"REACT_268786","Pathway_name":"Defective CHST6 causes MCDC1","_row":"REACT_268786"} {"Pathway":"REACT_111108","Pathway_name":"Mitochondrial ABC transporters","_row":"REACT_111108"} {"Pathway":"REACT_160176","Pathway_name":"Cytosolic iron-sulfur cluster assembly","_row":"REACT_160176"} {"Pathway":"REACT_19230","Pathway_name":"Role of Abl in Robo-Slit signaling","_row":"REACT_19230"} {"Pathway":"REACT_121401","Pathway_name":"Glycerophospholipid biosynthesis","_row":"REACT_121401"} {"Pathway":"REACT_264594","Pathway_name":"misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling","_row":"REACT_264594"} {"Pathway":"REACT_150201","Pathway_name":"Synthesis of 12-eicosatetraenoic acid derivatives","_row":"REACT_150201"} {"Pathway":"REACT_23862","Pathway_name":"Nitric oxide stimulates guanylate cyclase","_row":"REACT_23862"} {"Pathway":"REACT_16967","Pathway_name":"Post-chaperonin tubulin folding pathway","_row":"REACT_16967"} {"Pathway":"REACT_22433","Pathway_name":"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein","_row":"REACT_22433"} {"Pathway":"REACT_268619","Pathway_name":"Defective MPDU1 causes MPDU1-CDG (CDG-1f)","_row":"REACT_268619"} {"Pathway":"REACT_121111","Pathway_name":"Downregulation of SMAD2/3:SMAD4 transcriptional activity","_row":"REACT_121111"} {"Pathway":"REACT_13796","Pathway_name":"Amino acid transport across the plasma membrane","_row":"REACT_13796"} {"Pathway":"REACT_6776","Pathway_name":"Unwinding of DNA","_row":"REACT_6776"} {"Pathway":"REACT_18368","Pathway_name":"IRE1alpha activates chaperones","_row":"REACT_18368"} {"Pathway":"REACT_6866","Pathway_name":"Autointegration results in viral DNA circles","_row":"REACT_6866"} {"Pathway":"REACT_6918","Pathway_name":"Integration of provirus","_row":"REACT_6918"} {"Pathway":"REACT_9058","Pathway_name":"2-LTR circle formation","_row":"REACT_9058"} {"Pathway":"REACT_8990","Pathway_name":"Integration of viral DNA into host genomic DNA","_row":"REACT_8990"} {"Pathway":"REACT_9406","Pathway_name":"APOBEC3G mediated resistance to HIV-1 infection","_row":"REACT_9406"} {"Pathway":"REACT_264071","Pathway_name":"HSF1 activation","_row":"REACT_264071"} {"Pathway":"REACT_264164","Pathway_name":"HSF1-dependent transactivation","_row":"REACT_264164"} {"Pathway":"REACT_264075","Pathway_name":"Attenuation phase","_row":"REACT_264075"} {"Pathway":"REACT_160251","Pathway_name":"Clearance of Nuclear Envelope Membranes from Chromatin","_row":"REACT_160251"} {"Pathway":"REACT_160242","Pathway_name":"Initiation of Nuclear Envelope Reformation","_row":"REACT_160242"} {"Pathway":"REACT_118560","Pathway_name":"Small interfering RNA (siRNA) biogenesis","_row":"REACT_118560"} {"Pathway":"REACT_1230","Pathway_name":"Platelet Adhesion to exposed collagen","_row":"REACT_1230"} {"Pathway":"REACT_12524","Pathway_name":"CREB phosphorylation","_row":"REACT_12524"} {"Pathway":"REACT_12599","Pathway_name":"ERK/MAPK targets","_row":"REACT_12599"} {"Pathway":"REACT_355503","Pathway_name":"CD209 (DC-SIGN) signaling","_row":"REACT_355503"} {"Pathway":"REACT_150238","Pathway_name":"Signaling by Activin","_row":"REACT_150238"} {"Pathway":"REACT_355072","Pathway_name":"TNFR1-mediated proapoptotic signaling","_row":"REACT_355072"} {"Pathway":"REACT_12477","Pathway_name":"eNOS activation","_row":"REACT_12477"} {"Pathway":"REACT_9509","Pathway_name":"Gap junction assembly","_row":"REACT_9509"} {"Pathway":"REACT_169333","Pathway_name":"TRP channels","_row":"REACT_169333"} {"Pathway":"REACT_147707","Pathway_name":"Metabolism of Angiotensinogen to Angiotensins","_row":"REACT_147707"} {"Pathway":"REACT_19183","Pathway_name":"CD28 co-stimulation","_row":"REACT_19183"} {"Pathway":"REACT_9405","Pathway_name":"Cholesterol biosynthesis","_row":"REACT_9405"} {"Pathway":"REACT_16904","Pathway_name":"NADPH regeneration","_row":"REACT_16904"} {"Pathway":"REACT_160183","Pathway_name":"Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate","_row":"REACT_160183"} {"Pathway":"REACT_11048","Pathway_name":"Synthesis of bile acids and bile salts via 27-hydroxycholesterol","_row":"REACT_11048"} {"Pathway":"REACT_13812","Pathway_name":"Endogenous sterols","_row":"REACT_13812"} {"Pathway":"REACT_11054","Pathway_name":"Synthesis of bile acids and bile salts","_row":"REACT_11054"} {"Pathway":"REACT_267709","Pathway_name":"Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)","_row":"REACT_267709"} {"Pathway":"REACT_25031","Pathway_name":"GABA B receptor activation","_row":"REACT_25031"} {"Pathway":"REACT_121122","Pathway_name":"Acyl chain remodeling of DAG and TAG","_row":"REACT_121122"} {"Pathway":"REACT_160083","Pathway_name":"The retinoid cycle in cones (daylight vision)","_row":"REACT_160083"} {"Pathway":"REACT_2202","Pathway_name":"Effects of PIP2 hydrolysis","_row":"REACT_2202"} {"Pathway":"REACT_19238","Pathway_name":"CD28 dependent Vav1 pathway","_row":"REACT_19238"} {"Pathway":"REACT_17044","Pathway_name":"Muscle contraction","_row":"REACT_17044"} {"Pathway":"REACT_2125","Pathway_name":"Carnitine synthesis","_row":"REACT_2125"} {"Pathway":"REACT_6759","Pathway_name":"Formation of ATP by chemiosmotic coupling","_row":"REACT_6759"} {"Pathway":"REACT_115902","Pathway_name":"SRP-dependent cotranslational protein targeting to membrane","_row":"REACT_115902"} {"Pathway":"REACT_952","Pathway_name":"Synthesis of glycosylphosphatidylinositol (GPI)","_row":"REACT_952"} {"Pathway":"REACT_18265","Pathway_name":"Regulation of the Fanconi anemia pathway","_row":"REACT_18265"} {"Pathway":"REACT_355480","Pathway_name":"Recognition of DNA damage by PCNA-containing replication complex","_row":"REACT_355480"} {"Pathway":"REACT_22394","Pathway_name":"Synthesis of UDP-N-acetyl-glucosamine","_row":"REACT_22394"} {"Pathway":"REACT_19376","Pathway_name":"Regulation of Commissural axon pathfinding by Slit and Robo","_row":"REACT_19376"} {"Pathway":"REACT_19351","Pathway_name":"Signaling by Robo receptor","_row":"REACT_19351"} {"Pathway":"REACT_12507","Pathway_name":"COPII (Coat Protein 2) Mediated Vesicle Transport","_row":"REACT_12507"} {"Pathway":"REACT_238","Pathway_name":"Amino acid synthesis and interconversion (transamination)","_row":"REACT_238"} {"Pathway":"REACT_23988","Pathway_name":"Transport of organic anions","_row":"REACT_23988"} {"Pathway":"REACT_12435","Pathway_name":"Retrograde neurotrophin signalling","_row":"REACT_12435"} {"Pathway":"REACT_11200","Pathway_name":"Nef Mediated CD8 Down-regulation","_row":"REACT_11200"} {"Pathway":"REACT_11166","Pathway_name":"Nef Mediated CD4 Down-regulation","_row":"REACT_11166"} {"Pathway":"REACT_18422","Pathway_name":"Trafficking of GluR2-containing AMPA receptors","_row":"REACT_18422"} {"Pathway":"REACT_1023","Pathway_name":"Pyrimidine catabolism","_row":"REACT_1023"} {"Pathway":"REACT_160122","Pathway_name":"Activation of NIMA Kinases NEK9, NEK6, NEK7","_row":"REACT_160122"} {"Pathway":"REACT_2101","Pathway_name":"Cyclin B2 mediated events","_row":"REACT_2101"} {"Pathway":"REACT_1006","Pathway_name":"Polo-like kinase mediated events","_row":"REACT_1006"} {"Pathway":"REACT_1846","Pathway_name":"G2/M DNA replication checkpoint","_row":"REACT_1846"} {"Pathway":"REACT_150260","Pathway_name":"Condensation of Prometaphase Chromosomes","_row":"REACT_150260"} {"Pathway":"REACT_75819","Pathway_name":"TWIK related potassium channel (TREK)","_row":"REACT_75819"} {"Pathway":"REACT_13819","Pathway_name":"Regulation of gene expression in beta cells","_row":"REACT_13819"} {"Pathway":"REACT_18365","Pathway_name":"Lysosphingolipid and LPA receptors","_row":"REACT_18365"} {"Pathway":"REACT_22384","Pathway_name":"Netrin mediated repulsion signals","_row":"REACT_22384"} {"Pathway":"REACT_1932","Pathway_name":"Mitotic Telophase/Cytokinesis","_row":"REACT_1932"} {"Pathway":"REACT_160130","Pathway_name":"Retinoid cycle disease events","_row":"REACT_160130"} {"Pathway":"REACT_6196","Pathway_name":"The proton buffering model","_row":"REACT_6196"} {"Pathway":"REACT_6258","Pathway_name":"The fatty acid cycling model","_row":"REACT_6258"} {"Pathway":"REACT_23898","Pathway_name":"Rap1 signalling","_row":"REACT_23898"} {"Pathway":"REACT_118778","Pathway_name":"Activation of RAS in B cells","_row":"REACT_118778"} {"Pathway":"REACT_264356","Pathway_name":"XAV939 inhibits tankyrase, stabilizing AXIN","_row":"REACT_264356"} {"Pathway":"REACT_1859","Pathway_name":"Pentose phosphate pathway (hexose monophosphate shunt)","_row":"REACT_1859"} {"Pathway":"REACT_268843","Pathway_name":"Defective PAPSS2 causes SEMD-PA","_row":"REACT_268843"} {"Pathway":"REACT_15302","Pathway_name":"Mitochondrial tRNA aminoacylation","_row":"REACT_15302"} {"Pathway":"REACT_150331","Pathway_name":"Molecules associated with elastic fibres","_row":"REACT_150331"} {"Pathway":"REACT_25073","Pathway_name":"Molybdenum cofactor biosynthesis","_row":"REACT_25073"} {"Pathway":"REACT_169103","Pathway_name":"SMAD2/3 Phosphorylation Motif Mutants in Cancer","_row":"REACT_169103"} {"Pathway":"REACT_169165","Pathway_name":"SMAD2/3 MH2 Domain Mutants in Cancer","_row":"REACT_169165"} {"Pathway":"REACT_169263","Pathway_name":"TGFBR1 KD Mutants in Cancer","_row":"REACT_169263"} {"Pathway":"REACT_120850","Pathway_name":"TGF-beta receptor signaling activates SMADs","_row":"REACT_120850"} {"Pathway":"REACT_1432","Pathway_name":"TNF signaling","_row":"REACT_1432"} {"Pathway":"REACT_19411","Pathway_name":"Type II Na+/Pi cotransporters","_row":"REACT_19411"} {"Pathway":"REACT_25042","Pathway_name":"KSRP destabilizes mRNA","_row":"REACT_25042"} {"Pathway":"REACT_18355","Pathway_name":"ATF4 activates genes","_row":"REACT_18355"} {"Pathway":"REACT_263908","Pathway_name":"Depolymerisation of the Nuclear Lamina","_row":"REACT_263908"} {"Pathway":"REACT_19343","Pathway_name":"Facilitative Na+-independent glucose transporters","_row":"REACT_19343"} {"Pathway":"REACT_11088","Pathway_name":"Nicotinate metabolism","_row":"REACT_11088"} {"Pathway":"REACT_116010","Pathway_name":"Sulfide oxidation to sulfate","_row":"REACT_116010"} {"Pathway":"REACT_22228","Pathway_name":"Role of second messengers in netrin-1 signaling","_row":"REACT_22228"} {"Pathway":"REACT_150276","Pathway_name":"Antagonism of Activin by Follistatin","_row":"REACT_150276"} {"Pathway":"REACT_6173","Pathway_name":"Inhibition of Host mRNA Processing and RNA Silencing","_row":"REACT_6173"} {"Pathway":"REACT_111046","Pathway_name":"betaKlotho-mediated ligand binding","_row":"REACT_111046"} {"Pathway":"REACT_25026","Pathway_name":"TRAF3-dependent IRF activation pathway","_row":"REACT_25026"} {"Pathway":"REACT_24938","Pathway_name":"TRAF6 mediated IRF7 activation","_row":"REACT_24938"} {"Pathway":"REACT_16957","Pathway_name":"Peroxisomal lipid metabolism","_row":"REACT_16957"} {"Pathway":"REACT_18405","Pathway_name":"Acetylcholine regulates insulin secretion","_row":"REACT_18405"} {"Pathway":"REACT_1249","Pathway_name":"Histidine catabolism","_row":"REACT_1249"} {"Pathway":"REACT_1625","Pathway_name":"p53-Dependent G1 DNA Damage Response","_row":"REACT_1625"} {"Pathway":"REACT_308","Pathway_name":"Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes","_row":"REACT_308"} {"Pathway":"REACT_111214","Pathway_name":"G0 and Early G1","_row":"REACT_111214"} {"Pathway":"REACT_1574","Pathway_name":"Cyclin E associated events during G1/S transition ","_row":"REACT_1574"} {"Pathway":"REACT_11202","Pathway_name":"Vitamin C (ascorbate) metabolism","_row":"REACT_11202"} {"Pathway":"REACT_34","Pathway_name":"Ethanol oxidation","_row":"REACT_34"} {"Pathway":"REACT_11167","Pathway_name":"Metabolism of folate and pterines","_row":"REACT_11167"} {"Pathway":"REACT_111176","Pathway_name":"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation","_row":"REACT_111176"} {"Pathway":"REACT_121117","Pathway_name":"Phenylketonuria","_row":"REACT_121117"} {"Pathway":"REACT_25060","Pathway_name":"Iron uptake and transport","_row":"REACT_25060"} {"Pathway":"REACT_1439","Pathway_name":"Common Pathway of Fibrin Clot Formation","_row":"REACT_1439"} {"Pathway":"REACT_326","Pathway_name":"Intrinsic Pathway of Fibrin Clot Formation","_row":"REACT_326"} {"Pathway":"REACT_847","Pathway_name":"Urea cycle","_row":"REACT_847"} {"Pathway":"REACT_2086","Pathway_name":"Purine catabolism","_row":"REACT_2086"} {"Pathway":"REACT_1923","Pathway_name":"Purine salvage","_row":"REACT_1923"} {"Pathway":"REACT_12578","Pathway_name":"GAB1 signalosome","_row":"REACT_12578"} {"Pathway":"REACT_12606","Pathway_name":"GRB2 events in EGFR signaling","_row":"REACT_12606"} {"Pathway":"REACT_268595","Pathway_name":"Inhibition of Signaling by Overexpressed EGFR","_row":"REACT_268595"} {"Pathway":"REACT_115720","Pathway_name":"PLCG1 events in ERBB2 signaling","_row":"REACT_115720"} {"Pathway":"REACT_12478","Pathway_name":"EGFR interacts with phospholipase C-gamma","_row":"REACT_12478"} {"Pathway":"REACT_121096","Pathway_name":"EGFR Transactivation by Gastrin","_row":"REACT_121096"} {"Pathway":"REACT_12579","Pathway_name":"SHC1 events in EGFR signaling","_row":"REACT_12579"} {"Pathway":"REACT_115852","Pathway_name":"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants","_row":"REACT_115852"} {"Pathway":"REACT_267817","Pathway_name":"Constitutive Signaling by EGFRvIII","_row":"REACT_267817"} {"Pathway":"REACT_268571","Pathway_name":"Uptake and function of diphtheria toxin","_row":"REACT_268571"} {"Pathway":"REACT_355374","Pathway_name":"Lactose synthesis","_row":"REACT_355374"} {"Pathway":"REACT_1906","Pathway_name":"Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus","_row":"REACT_1906"} {"Pathway":"REACT_15428","Pathway_name":"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)","_row":"REACT_15428"} {"Pathway":"REACT_733","Pathway_name":"Removal of aminoterminal propeptides from gamma-carboxylated proteins","_row":"REACT_733"} {"Pathway":"REACT_278","Pathway_name":"Platelet Aggregation (Plug Formation)","_row":"REACT_278"} {"Pathway":"REACT_1050","Pathway_name":"Gamma-carboxylation of protein precursors","_row":"REACT_1050"} {"Pathway":"REACT_12051","Pathway_name":"Cell surface interactions at the vascular wall","_row":"REACT_12051"} {"Pathway":"REACT_1573","Pathway_name":"Extrinsic Pathway of Fibrin Clot Formation","_row":"REACT_1573"} {"Pathway":"REACT_8001","Pathway_name":"Alternative complement activation","_row":"REACT_8001"} {"Pathway":"REACT_641","Pathway_name":"Dissolution of Fibrin Clot","_row":"REACT_641"} {"Pathway":"REACT_118707","Pathway_name":"Regulation of Complement cascade","_row":"REACT_118707"} {"Pathway":"REACT_7972","Pathway_name":"Activation of C3 and C5","_row":"REACT_7972"} {"Pathway":"REACT_121329","Pathway_name":"Erythrocytes take up carbon dioxide and release oxygen","_row":"REACT_121329"} {"Pathway":"REACT_121380","Pathway_name":"Erythrocytes take up oxygen and release carbon dioxide","_row":"REACT_121380"} {"Pathway":"REACT_8028","Pathway_name":"Terminal pathway of complement","_row":"REACT_8028"} {"Pathway":"REACT_21326","Pathway_name":"Activation of the AP-1 family of transcription factors","_row":"REACT_21326"} {"Pathway":"REACT_9029","Pathway_name":"Cyclin A:Cdk2-associated events at S phase entry","_row":"REACT_9029"} {"Pathway":"REACT_264532","Pathway_name":"binding of TCF/LEF:CTNNB1 to target gene promoters","_row":"REACT_264532"} {"Pathway":"REACT_962","Pathway_name":"MEK activation","_row":"REACT_962"} {"Pathway":"REACT_614","Pathway_name":"RAF phosphorylates MEK","_row":"REACT_614"} {"Pathway":"REACT_524","Pathway_name":"SOS-mediated signalling","_row":"REACT_524"} {"Pathway":"REACT_661","Pathway_name":"SHC-mediated signalling","_row":"REACT_661"} {"Pathway":"REACT_2077","Pathway_name":"RAF activation","_row":"REACT_2077"} {"Pathway":"REACT_12033","Pathway_name":"Signalling to RAS","_row":"REACT_12033"} {"Pathway":"REACT_6934","Pathway_name":"LDL-mediated lipid transport","_row":"REACT_6934"} {"Pathway":"REACT_6841","Pathway_name":"Chylomicron-mediated lipid transport","_row":"REACT_6841"} {"Pathway":"REACT_120726","Pathway_name":"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)","_row":"REACT_120726"} {"Pathway":"REACT_169192","Pathway_name":"TGFBR2 MSI Frameshift Mutants in Cancer","_row":"REACT_169192"} {"Pathway":"REACT_169440","Pathway_name":"TGFBR2 Kinase Domain Mutants in Cancer","_row":"REACT_169440"} {"Pathway":"REACT_169445","Pathway_name":"TGFBR1 LBD Mutants in Cancer","_row":"REACT_169445"} {"Pathway":"REACT_6213","Pathway_name":"Influenza Virus Induced Apoptosis","_row":"REACT_6213"} {"Pathway":"REACT_13779","Pathway_name":"Axonal growth stimulation","_row":"REACT_13779"} {"Pathway":"REACT_12002","Pathway_name":"ARMS-mediated activation","_row":"REACT_12002"} {"Pathway":"REACT_11060","Pathway_name":"TRKA activation by NGF","_row":"REACT_11060"} {"Pathway":"REACT_13643","Pathway_name":"NRIF signals cell death from the nucleus","_row":"REACT_13643"} {"Pathway":"REACT_11062","Pathway_name":"NGF processing","_row":"REACT_11062"} {"Pathway":"REACT_13724","Pathway_name":"NFG and proNGF binds to p75NTR","_row":"REACT_13724"} {"Pathway":"REACT_12049","Pathway_name":"Signalling to STAT3","_row":"REACT_12049"} {"Pathway":"REACT_12079","Pathway_name":"PLC-gamma1 signalling","_row":"REACT_12079"} {"Pathway":"REACT_13526","Pathway_name":"NADE modulates death signalling","_row":"REACT_13526"} {"Pathway":"REACT_12077","Pathway_name":"Signalling to p38 via RIT and RIN","_row":"REACT_12077"} {"Pathway":"REACT_12076","Pathway_name":"Frs2-mediated activation","_row":"REACT_12076"} {"Pathway":"REACT_17041","Pathway_name":"Vasopressin-like receptors","_row":"REACT_17041"} {"Pathway":"REACT_267874","Pathway_name":"Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)","_row":"REACT_267874"} {"Pathway":"REACT_11036","Pathway_name":"Glucocorticoid biosynthesis","_row":"REACT_11036"} {"Pathway":"REACT_15295","Pathway_name":"Opioid Signalling","_row":"REACT_15295"} {"Pathway":"REACT_15452","Pathway_name":"Peptide hormone biosynthesis","_row":"REACT_15452"} {"Pathway":"REACT_11059","Pathway_name":"Androgen biosynthesis","_row":"REACT_11059"} {"Pathway":"REACT_15398","Pathway_name":"Glycoprotein hormones","_row":"REACT_15398"} {"Pathway":"REACT_11047","Pathway_name":"Mineralocorticoid biosynthesis","_row":"REACT_11047"} {"Pathway":"REACT_15292","Pathway_name":"Thyroxine biosynthesis","_row":"REACT_15292"} {"Pathway":"REACT_570","Pathway_name":"IRS activation","_row":"REACT_570"} {"Pathway":"REACT_508","Pathway_name":"Signal attenuation","_row":"REACT_508"} {"Pathway":"REACT_1661","Pathway_name":"SHC activation","_row":"REACT_1661"} {"Pathway":"REACT_498","Pathway_name":"Signaling by Insulin receptor","_row":"REACT_498"} {"Pathway":"REACT_150359","Pathway_name":"Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)","_row":"REACT_150359"} {"Pathway":"REACT_150139","Pathway_name":"SHC-related events triggered by IGF1R","_row":"REACT_150139"} {"Pathway":"REACT_120966","Pathway_name":"Gastrin-CREB signalling pathway via PKC and MAPK","_row":"REACT_120966"} {"Pathway":"REACT_23950","Pathway_name":"Interleukin-1 processing","_row":"REACT_23950"} {"Pathway":"REACT_355550","Pathway_name":"CLEC7A/inflammasome pathway","_row":"REACT_355550"} {"Pathway":"REACT_121092","Pathway_name":"Regulation of gene expression by Hypoxia-inducible Factor","_row":"REACT_121092"} {"Pathway":"REACT_12596","Pathway_name":"Translocation of ZAP-70 to Immunological synapse","_row":"REACT_12596"} {"Pathway":"REACT_115574","Pathway_name":"Alpha-defensins","_row":"REACT_115574"} {"Pathway":"REACT_19324","Pathway_name":"PD-1 signaling","_row":"REACT_19324"} {"Pathway":"REACT_12582","Pathway_name":"Phosphorylation of CD3 and TCR zeta chains","_row":"REACT_12582"} {"Pathway":"REACT_6903","Pathway_name":"Binding and entry of HIV virion","_row":"REACT_6903"} {"Pathway":"REACT_118779","Pathway_name":"Extracellular matrix organization","_row":"REACT_118779"} {"Pathway":"REACT_163699","Pathway_name":"Scavenging by Class A Receptors","_row":"REACT_163699"} {"Pathway":"REACT_20537","Pathway_name":"Type I hemidesmosome assembly","_row":"REACT_20537"} {"Pathway":"REACT_13472","Pathway_name":"Breakdown of the nuclear lamina","_row":"REACT_13472"} {"Pathway":"REACT_163679","Pathway_name":"Scavenging by Class B Receptors","_row":"REACT_163679"} {"Pathway":"REACT_111158","Pathway_name":"ABCA transporters in lipid homeostasis","_row":"REACT_111158"} {"Pathway":"REACT_15381","Pathway_name":"p130Cas linkage to MAPK signaling for integrins","_row":"REACT_15381"} {"Pathway":"REACT_15443","Pathway_name":"GRB2:SOS provides linkage to MAPK signaling for Integrins ","_row":"REACT_15443"} {"Pathway":"REACT_22303","Pathway_name":"Highly calcium permeable postsynaptic nicotinic acetylcholine receptors","_row":"REACT_22303"} {"Pathway":"REACT_22352","Pathway_name":"Highly calcium permeable nicotinic acetylcholine receptors","_row":"REACT_22352"} {"Pathway":"REACT_19298","Pathway_name":"Bicarbonate transporters","_row":"REACT_19298"} {"Pathway":"REACT_160131","Pathway_name":"Fibronectin matrix formation","_row":"REACT_160131"} {"Pathway":"REACT_121118","Pathway_name":"Mtb iron assimilation by chelation","_row":"REACT_121118"} {"Pathway":"REACT_355442","Pathway_name":"Dectin-2 family","_row":"REACT_355442"} {"Pathway":"REACT_9491","Pathway_name":"Viral mRNA Translation","_row":"REACT_9491"} {"Pathway":"REACT_6248","Pathway_name":"Transport of Ribonucleoproteins into the Host Nucleus","_row":"REACT_6248"} {"Pathway":"REACT_6277","Pathway_name":"Assembly of Viral Components at the Budding Site","_row":"REACT_6277"} {"Pathway":"REACT_6350","Pathway_name":"Inhibition of PKR","_row":"REACT_6350"} {"Pathway":"REACT_23847","Pathway_name":"GP1b-IX-V activation signalling","_row":"REACT_23847"} {"Pathway":"REACT_20568","Pathway_name":"CREB phosphorylation through the activation of Ras","_row":"REACT_20568"} {"Pathway":"REACT_21264","Pathway_name":"Formyl peptide receptors bind formyl peptides and many other ligands","_row":"REACT_21264"} {"Pathway":"REACT_21314","Pathway_name":"Relaxin receptors","_row":"REACT_21314"} {"Pathway":"REACT_164002","Pathway_name":"Scavenging by Class H Receptors","_row":"REACT_164002"} {"Pathway":"REACT_23879","Pathway_name":"Platelet sensitization by LDL","_row":"REACT_23879"} {"Pathway":"REACT_163813","Pathway_name":"Scavenging by Class F Receptors","_row":"REACT_163813"} {"Pathway":"REACT_9518","Pathway_name":"Digestion of dietary lipid","_row":"REACT_9518"} {"Pathway":"REACT_163773","Pathway_name":"DEx/H-box helicases activate type I IFN and inflammatory cytokines production ","_row":"REACT_163773"} {"Pathway":"REACT_25195","Pathway_name":"Advanced glycosylation endproduct receptor signaling","_row":"REACT_25195"} {"Pathway":"REACT_11039","Pathway_name":"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane","_row":"REACT_11039"} {"Pathway":"REACT_268265","Pathway_name":"Assembly of the primary cilium","_row":"REACT_268265"} {"Pathway":"REACT_15510","Pathway_name":"Recruitment of NuMA to mitotic centrosomes","_row":"REACT_15510"} {"Pathway":"REACT_16956","Pathway_name":"Formation of tubulin folding intermediates by CCT/TriC","_row":"REACT_16956"} {"Pathway":"REACT_6818","Pathway_name":"Assembly Of The HIV Virion","_row":"REACT_6818"} {"Pathway":"REACT_163660","Pathway_name":"Synthesis and processing of ENV and VPU","_row":"REACT_163660"} {"Pathway":"REACT_9055","Pathway_name":"Minus-strand DNA synthesis","_row":"REACT_9055"} {"Pathway":"REACT_6965","Pathway_name":"Uncoating of the HIV Virion","_row":"REACT_6965"} {"Pathway":"REACT_9037","Pathway_name":"Plus-strand DNA synthesis","_row":"REACT_9037"} {"Pathway":"REACT_6266","Pathway_name":"Early Phase of HIV Life Cycle","_row":"REACT_6266"} {"Pathway":"REACT_11139","Pathway_name":"Nef mediated downregulation of CD28 cell surface expression","_row":"REACT_11139"} {"Pathway":"REACT_6361","Pathway_name":"Late Phase of HIV Life Cycle","_row":"REACT_6361"} {"Pathway":"REACT_11068","Pathway_name":"Nef and signal transduction","_row":"REACT_11068"} {"Pathway":"REACT_11046","Pathway_name":"NGF-independant TRKA activation","_row":"REACT_11046"} {"Pathway":"REACT_346","Pathway_name":"Transcriptional activation of cell cycle inhibitor p21 ","_row":"REACT_346"} {"Pathway":"REACT_1194","Pathway_name":"Activation of NOXA and translocation to mitochondria","_row":"REACT_1194"} {"Pathway":"REACT_169121","Pathway_name":"Formation of Senescence-Associated Heterochromatin Foci (SAHF)","_row":"REACT_169121"} {"Pathway":"REACT_309","Pathway_name":"Stabilization of p53","_row":"REACT_309"} {"Pathway":"REACT_121","Pathway_name":"Activation of PUMA and translocation to mitochondria","_row":"REACT_121"} {"Pathway":"REACT_13543","Pathway_name":"Xenobiotics","_row":"REACT_13543"} {"Pathway":"REACT_150134","Pathway_name":"Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)","_row":"REACT_150134"} {"Pathway":"REACT_150417","Pathway_name":"Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)","_row":"REACT_150417"} {"Pathway":"REACT_21376","Pathway_name":"Pyrimidine biosynthesis","_row":"REACT_21376"} {"Pathway":"REACT_355141","Pathway_name":"RHO GTPases Activate NADPH Oxidases","_row":"REACT_355141"} {"Pathway":"REACT_111174","Pathway_name":"Cross-presentation of particulate exogenous antigens (phagosomes)","_row":"REACT_111174"} {"Pathway":"REACT_22426","Pathway_name":"Asparagine N-linked glycosylation","_row":"REACT_22426"} {"Pathway":"REACT_268602","Pathway_name":"Toxicity of tetanus toxin (TeNT)","_row":"REACT_268602"} {"Pathway":"REACT_1571","Pathway_name":"Fructose catabolism","_row":"REACT_1571"} {"Pathway":"REACT_355030","Pathway_name":"Hereditary fructose intolerance","_row":"REACT_355030"} {"Pathway":"REACT_23892","Pathway_name":"Transport of fatty acids","_row":"REACT_23892"} {"Pathway":"REACT_15532","Pathway_name":"Metabolism of serotonin","_row":"REACT_15532"} {"Pathway":"REACT_268217","Pathway_name":"Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)","_row":"REACT_268217"} {"Pathway":"REACT_150366","Pathway_name":"Elastic fibre formation","_row":"REACT_150366"} {"Pathway":"REACT_12519","Pathway_name":"PECAM1 interactions","_row":"REACT_12519"} {"Pathway":"REACT_268767","Pathway_name":"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)","_row":"REACT_268767"} {"Pathway":"REACT_11038","Pathway_name":"Pregnenolone biosynthesis","_row":"REACT_11038"} {"Pathway":"REACT_9000","Pathway_name":"Calmodulin induced events","_row":"REACT_9000"} {"Pathway":"REACT_1280","Pathway_name":"Response to elevated platelet cytosolic Ca2+","_row":"REACT_1280"} {"Pathway":"REACT_8016","Pathway_name":"Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization","_row":"REACT_8016"} {"Pathway":"REACT_993","Pathway_name":"Propionyl-CoA catabolism","_row":"REACT_993"} {"Pathway":"REACT_6946","Pathway_name":"Methylation","_row":"REACT_6946"} {"Pathway":"REACT_13721","Pathway_name":"Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2","_row":"REACT_13721"} {"Pathway":"REACT_13797","Pathway_name":"CYP2E1 reactions","_row":"REACT_13797"} {"Pathway":"REACT_1815","Pathway_name":"Recycling of eIF2:GDP","_row":"REACT_1815"} {"Pathway":"REACT_18277","Pathway_name":"PERK regulates gene expression","_row":"REACT_18277"} {"Pathway":"REACT_1986","Pathway_name":"Eukaryotic Translation Termination","_row":"REACT_1986"} {"Pathway":"REACT_1404","Pathway_name":"Peptide chain elongation","_row":"REACT_1404"} {"Pathway":"REACT_75768","Pathway_name":"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)","_row":"REACT_75768"} {"Pathway":"REACT_20617","Pathway_name":"Localization of the PINCH-ILK-PARVIN complex to focal adhesions","_row":"REACT_20617"} {"Pathway":"REACT_9465","Pathway_name":"Heme biosynthesis","_row":"REACT_9465"} {"Pathway":"REACT_75892","Pathway_name":"The IPAF inflammasome","_row":"REACT_75892"} {"Pathway":"REACT_121238","Pathway_name":"Synthesis of PC","_row":"REACT_121238"} {"Pathway":"REACT_329","Pathway_name":"Inhibition of replication initiation of damaged DNA by RB1/E2F1","_row":"REACT_329"} {"Pathway":"REACT_6875","Pathway_name":"Phosphorylation of Emi1","_row":"REACT_6875"} {"Pathway":"REACT_6362","Pathway_name":"Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes","_row":"REACT_6362"} {"Pathway":"REACT_1835","Pathway_name":"Transport of Mature mRNA Derived from an Intronless Transcript","_row":"REACT_1835"} {"Pathway":"REACT_405","Pathway_name":"Transport of the SLBP Dependant Mature mRNA","_row":"REACT_405"} {"Pathway":"REACT_6836","Pathway_name":"Release of eIF4E","_row":"REACT_6836"} {"Pathway":"REACT_424","Pathway_name":"Transport of the SLBP independent Mature mRNA","_row":"REACT_424"} {"Pathway":"REACT_1258","Pathway_name":"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S","_row":"REACT_1258"} {"Pathway":"REACT_813","Pathway_name":"Creatine metabolism","_row":"REACT_813"} {"Pathway":"REACT_163910","Pathway_name":"NOTCH2 intracellular domain regulates transcription","_row":"REACT_163910"} {"Pathway":"REACT_933","Pathway_name":"Resolution of AP sites via the single-nucleotide replacement pathway","_row":"REACT_933"} {"Pathway":"REACT_355510","Pathway_name":"PCNA-Dependent Long Patch Base Excision Repair","_row":"REACT_355510"} {"Pathway":"REACT_1357","Pathway_name":"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway","_row":"REACT_1357"} {"Pathway":"REACT_1128","Pathway_name":"Resolution of AP sites via the multiple-nucleotide patch replacement pathway","_row":"REACT_1128"} {"Pathway":"REACT_2192","Pathway_name":"POLB-Dependent Long Patch Base Excision Repair","_row":"REACT_2192"} {"Pathway":"REACT_15551","Pathway_name":"Catecholamine biosynthesis","_row":"REACT_15551"} {"Pathway":"REACT_150209","Pathway_name":"Synthesis of 5-eicosatetraenoic acids","_row":"REACT_150209"} {"Pathway":"REACT_121388","Pathway_name":"Abacavir metabolism","_row":"REACT_121388"} {"Pathway":"REACT_22223","Pathway_name":"Highly sodium permeable acetylcholine nicotinic receptors","_row":"REACT_22223"} {"Pathway":"REACT_16927","Pathway_name":"Adrenoceptors","_row":"REACT_16927"} {"Pathway":"REACT_532","Pathway_name":"Galactose catabolism","_row":"REACT_532"} {"Pathway":"REACT_257","Pathway_name":"Formation of incision complex in GG-NER","_row":"REACT_257"} {"Pathway":"REACT_311","Pathway_name":"Dual incision reaction in GG-NER","_row":"REACT_311"} {"Pathway":"REACT_9392","Pathway_name":"Transport of connexins along the secretory pathway","_row":"REACT_9392"} {"Pathway":"REACT_9398","Pathway_name":"Oligomerization of connexins into connexons","_row":"REACT_9398"} {"Pathway":"REACT_13443","Pathway_name":"Regulated proteolysis of p75NTR","_row":"REACT_13443"} {"Pathway":"REACT_13815","Pathway_name":"Axonal growth inhibition (RHOA activation)","_row":"REACT_13815"} {"Pathway":"REACT_268272","Pathway_name":"GLI proteins bind promoters of Hh responsive genes to promote transcription","_row":"REACT_268272"} {"Pathway":"REACT_16943","Pathway_name":"Muscarinic acetylcholine receptors","_row":"REACT_16943"} {"Pathway":"REACT_147759","Pathway_name":"MPS VII - Sly syndrome","_row":"REACT_147759"} {"Pathway":"REACT_6822","Pathway_name":"Transfer of LPS from LBP carrier to CD14","_row":"REACT_6822"} {"Pathway":"REACT_267893","Pathway_name":"Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)","_row":"REACT_267893"} {"Pathway":"REACT_121036","Pathway_name":"The activation of arylsulfatases","_row":"REACT_121036"} {"Pathway":"REACT_17064","Pathway_name":"Serotonin receptors","_row":"REACT_17064"} {"Pathway":"REACT_19180","Pathway_name":"Adrenaline signalling through Alpha-2 adrenergic receptor","_row":"REACT_19180"} {"Pathway":"REACT_11049","Pathway_name":"Formation of annular gap junctions","_row":"REACT_11049"} {"Pathway":"REACT_11035","Pathway_name":"Gap junction degradation","_row":"REACT_11035"} {"Pathway":"REACT_22297","Pathway_name":"Heme degradation","_row":"REACT_22297"} {"Pathway":"REACT_1298","Pathway_name":"Lysine catabolism","_row":"REACT_1298"} {"Pathway":"REACT_355465","Pathway_name":"Intestinal saccharidase deficiencies","_row":"REACT_355465"} {"Pathway":"REACT_1792","Pathway_name":"Polymerase switching","_row":"REACT_1792"} {"Pathway":"REACT_7987","Pathway_name":"Polymerase switching on the C-strand of the telomere","_row":"REACT_7987"} {"Pathway":"REACT_2244","Pathway_name":"DNA replication initiation","_row":"REACT_2244"} {"Pathway":"REACT_7993","Pathway_name":"Telomere C-strand synthesis initiation","_row":"REACT_7993"} {"Pathway":"REACT_1385","Pathway_name":"Processive synthesis on the lagging strand","_row":"REACT_1385"} {"Pathway":"REACT_1838","Pathway_name":"Leading Strand Synthesis","_row":"REACT_1838"} {"Pathway":"REACT_70","Pathway_name":"Removal of the Flap Intermediate","_row":"REACT_70"} {"Pathway":"REACT_150320","Pathway_name":"Synthesis of Lipoxins (LX)","_row":"REACT_150320"} {"Pathway":"REACT_150420","Pathway_name":"Synthesis of Leukotrienes (LT) and Eoxins (EX)","_row":"REACT_150420"} {"Pathway":"REACT_6812","Pathway_name":"Conjugation of salicylate with glycine","_row":"REACT_6812"} {"Pathway":"REACT_120977","Pathway_name":"Hydrolysis of LPC","_row":"REACT_120977"} {"Pathway":"REACT_163977","Pathway_name":"Regulation of innate immune responses to cytosolic DNA","_row":"REACT_163977"} {"Pathway":"REACT_120916","Pathway_name":"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha","_row":"REACT_120916"} {"Pathway":"REACT_115828","Pathway_name":"Downregulation of ERBB4 signaling","_row":"REACT_115828"} {"Pathway":"REACT_355361","Pathway_name":"Regulation of necroptotic cell death","_row":"REACT_355361"} {"Pathway":"REACT_1287","Pathway_name":"Translesion Synthesis by POLH","_row":"REACT_1287"} {"Pathway":"REACT_25120","Pathway_name":"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling","_row":"REACT_25120"} {"Pathway":"REACT_150128","Pathway_name":"Electron transport from NADPH to Ferredoxin","_row":"REACT_150128"} {"Pathway":"REACT_150353","Pathway_name":"Mitochondrial iron-sulfur cluster biogenesis","_row":"REACT_150353"} {"Pathway":"REACT_701","Pathway_name":"Activation, myristolyation of BID and translocation to mitochondria","_row":"REACT_701"} {"Pathway":"REACT_163938","Pathway_name":"Acrosome Reaction","_row":"REACT_163938"} {"Pathway":"REACT_549","Pathway_name":"Activation of BAD and translocation to mitochondria ","_row":"REACT_549"} {"Pathway":"REACT_75927","Pathway_name":"The NLRP1 inflammasome","_row":"REACT_75927"} {"Pathway":"REACT_13814","Pathway_name":"Fatty acids","_row":"REACT_13814"} {"Pathway":"REACT_13425","Pathway_name":"Miscellaneous substrates","_row":"REACT_13425"} {"Pathway":"REACT_15334","Pathway_name":"DARPP-32 events","_row":"REACT_15334"} {"Pathway":"REACT_264609","Pathway_name":"Toxicity of botulinum toxin type B (BoNT/B)","_row":"REACT_264609"} {"Pathway":"REACT_264537","Pathway_name":"Toxicity of botulinum toxin type A (BoNT/A)","_row":"REACT_264537"} {"Pathway":"REACT_18423","Pathway_name":"ATF6-alpha activates chaperone genes","_row":"REACT_18423"} {"Pathway":"REACT_9441","Pathway_name":"Hexose transport","_row":"REACT_9441"} {"Pathway":"REACT_6732","Pathway_name":"Acetylation","_row":"REACT_6732"} {"Pathway":"REACT_1697","Pathway_name":"Beta oxidation of octanoyl-CoA to hexanoyl-CoA","_row":"REACT_1697"} {"Pathway":"REACT_160","Pathway_name":"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids","_row":"REACT_160"} {"Pathway":"REACT_1708","Pathway_name":"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA","_row":"REACT_1708"} {"Pathway":"REACT_9484","Pathway_name":"FGFR1c and Klotho ligand binding and activation","_row":"REACT_9484"} {"Pathway":"REACT_11037","Pathway_name":"Estrogen biosynthesis","_row":"REACT_11037"} {"Pathway":"REACT_268478","Pathway_name":"Defective CYP19A1 causes Aromatase excess syndrome (AEXS)","_row":"REACT_268478"} {"Pathway":"REACT_850","Pathway_name":"5-Phosphoribose 1-diphosphate biosynthesis","_row":"REACT_850"} {"Pathway":"REACT_14820","Pathway_name":"Metabolism of polyamines","_row":"REACT_14820"} {"Pathway":"REACT_8027","Pathway_name":"Processive synthesis on the C-strand of the telomere","_row":"REACT_8027"} {"Pathway":"REACT_1993","Pathway_name":"Repair synthesis for gap-filling by DNA polymerase in TC-NER","_row":"REACT_1993"} {"Pathway":"REACT_7961","Pathway_name":"Telomere C-strand (Lagging Strand) Synthesis","_row":"REACT_7961"} {"Pathway":"REACT_264501","Pathway_name":"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)","_row":"REACT_264501"} {"Pathway":"REACT_378","Pathway_name":"Repair synthesis of patch ~27-30 bases long by DNA polymerase","_row":"REACT_378"} {"Pathway":"REACT_264347","Pathway_name":"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)","_row":"REACT_264347"} {"Pathway":"REACT_7999","Pathway_name":"Removal of the Flap Intermediate from the C-strand","_row":"REACT_7999"} {"Pathway":"REACT_20580","Pathway_name":"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components","_row":"REACT_20580"} {"Pathway":"REACT_13579","Pathway_name":"Apoptotic cleavage of cell adhesion proteins","_row":"REACT_13579"} {"Pathway":"REACT_11043","Pathway_name":"c-src mediated regulation of Cx43 function and closure of gap junctions","_row":"REACT_11043"} {"Pathway":"REACT_1022","Pathway_name":"Nonhomologous End-joining (NHEJ)","_row":"REACT_1022"} {"Pathway":"REACT_1201","Pathway_name":"Processing of DNA ends prior to end rejoining","_row":"REACT_1201"} {"Pathway":"REACT_163993","Pathway_name":"IRF3-mediated induction of type I IFN","_row":"REACT_163993"} {"Pathway":"REACT_355278","Pathway_name":"RHO GTPases regulate CFTR trafficking","_row":"REACT_355278"} {"Pathway":"REACT_13645","Pathway_name":"Eicosanoids","_row":"REACT_13645"} {"Pathway":"REACT_268628","Pathway_name":"Synthesis of diphthamide-EEF2","_row":"REACT_268628"} {"Pathway":"REACT_11070","Pathway_name":"Vitamin B2 (riboflavin) metabolism","_row":"REACT_11070"} {"Pathway":"REACT_19188","Pathway_name":"Inositol transporters","_row":"REACT_19188"} {"Pathway":"REACT_19165","Pathway_name":"Na+-dependent glucose transporters","_row":"REACT_19165"} {"Pathway":"REACT_23878","Pathway_name":"N-glycan trimming in the ER and Calnexin/Calreticulin cycle","_row":"REACT_23878"} {"Pathway":"REACT_23810","Pathway_name":"Calnexin/calreticulin cycle","_row":"REACT_23810"} {"Pathway":"REACT_16968","Pathway_name":"Dopamine receptors","_row":"REACT_16968"} {"Pathway":"REACT_1364","Pathway_name":"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs","_row":"REACT_1364"} {"Pathway":"REACT_185","Pathway_name":"SLBP independent Processing of Histone Pre-mRNAs","_row":"REACT_185"} {"Pathway":"REACT_355245","Pathway_name":"Melanin biosynthesis","_row":"REACT_355245"} {"Pathway":"REACT_16925","Pathway_name":"Glyoxylate metabolism","_row":"REACT_16925"} {"Pathway":"REACT_13639","Pathway_name":"Astrocytic Glutamate-Glutamine Uptake And Metabolism","_row":"REACT_13639"} {"Pathway":"REACT_355154","Pathway_name":"Fructose biosynthesis","_row":"REACT_355154"} {"Pathway":"REACT_19268","Pathway_name":"Nectin/Necl trans heterodimerization","_row":"REACT_19268"} {"Pathway":"REACT_268438","Pathway_name":"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)","_row":"REACT_268438"} {"Pathway":"REACT_268601","Pathway_name":"Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)","_row":"REACT_268601"} {"Pathway":"REACT_147749","Pathway_name":"MPS IIID - Sanfilippo syndrome D","_row":"REACT_147749"} {"Pathway":"REACT_147719","Pathway_name":"MPS VI - Maroteaux-Lamy syndrome","_row":"REACT_147719"} {"Pathway":"REACT_115835","Pathway_name":"Termination of O-glycan biosynthesis","_row":"REACT_115835"} {"Pathway":"REACT_408","Pathway_name":"Presynaptic phase of homologous DNA pairing and strand exchange","_row":"REACT_408"} {"Pathway":"REACT_2141","Pathway_name":"Assembly of the RAD51-ssDNA nucleoprotein complex","_row":"REACT_2141"} {"Pathway":"REACT_2055","Pathway_name":"Processing of DNA double-strand break ends","_row":"REACT_2055"} {"Pathway":"REACT_97","Pathway_name":"Recruitment of repair and signaling proteins to double-strand breaks","_row":"REACT_97"} {"Pathway":"REACT_705","Pathway_name":"PP2A-mediated dephosphorylation of key metabolic factors","_row":"REACT_705"} {"Pathway":"REACT_1525","Pathway_name":"PKA-mediated phosphorylation of key metabolic factors","_row":"REACT_1525"} {"Pathway":"REACT_1887","Pathway_name":"Beta oxidation of hexanoyl-CoA to butanoyl-CoA","_row":"REACT_1887"} {"Pathway":"REACT_419","Pathway_name":"Beta oxidation of butanoyl-CoA to acetyl-CoA","_row":"REACT_419"} {"Pathway":"REACT_15502","Pathway_name":"CaMK IV-mediated phosphorylation of CREB","_row":"REACT_15502"} {"Pathway":"REACT_15497","Pathway_name":"PKA-mediated phosphorylation of CREB","_row":"REACT_15497"} {"Pathway":"REACT_20661","Pathway_name":"CREB phosphorylation through the activation of CaMKK","_row":"REACT_20661"} {"Pathway":"REACT_11218","Pathway_name":"Coenzyme A biosynthesis","_row":"REACT_11218"} {"Pathway":"REACT_147798","Pathway_name":"MPS IV - Morquio syndrome B","_row":"REACT_147798"} {"Pathway":"REACT_355286","Pathway_name":"MGMT-mediated DNA damage reversal","_row":"REACT_355286"} {"Pathway":"REACT_75881","Pathway_name":"Methionine salvage pathway","_row":"REACT_75881"} {"Pathway":"REACT_15439","Pathway_name":"Serotonin and melatonin biosynthesis","_row":"REACT_15439"} {"Pathway":"REACT_17050","Pathway_name":"Folding of actin by CCT/TriC","_row":"REACT_17050"} {"Pathway":"REACT_150292","Pathway_name":"Synthesis of Hepoxilins (HX) and Trioxilins (TrX)","_row":"REACT_150292"} {"Pathway":"REACT_263969","Pathway_name":"Toxicity of botulinum toxin type C (BoNT/C)","_row":"REACT_263969"} {"Pathway":"REACT_74","Pathway_name":"Gap-filling DNA repair synthesis and ligation in TC-NER","_row":"REACT_74"} {"Pathway":"REACT_977","Pathway_name":"Resolution of D-loop structures through Holliday junction intermediates","_row":"REACT_977"} {"Pathway":"REACT_1998","Pathway_name":"Gap-filling DNA repair synthesis and ligation in GG-NER","_row":"REACT_1998"} {"Pathway":"REACT_268761","Pathway_name":"Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)","_row":"REACT_268761"} {"Pathway":"REACT_263924","Pathway_name":"Toxicity of botulinum toxin type D (BoNT/D)","_row":"REACT_263924"} {"Pathway":"REACT_268129","Pathway_name":"Defective GGT1 causes Glutathionuria (GLUTH)","_row":"REACT_268129"} {"Pathway":"REACT_147841","Pathway_name":"STING mediated induction of host immune responses","_row":"REACT_147841"} {"Pathway":"REACT_19314","Pathway_name":"Sodium/Proton exchangers","_row":"REACT_19314"} {"Pathway":"REACT_169178","Pathway_name":"Defective CD320 causes methylmalonic aciduria","_row":"REACT_169178"} {"Pathway":"REACT_169120","Pathway_name":"Defective TCN2 causes hereditary megaloblastic anemia","_row":"REACT_169120"} {"Pathway":"REACT_16963","Pathway_name":"Tachykinin receptors bind tachykinins","_row":"REACT_16963"} {"Pathway":"REACT_20649","Pathway_name":"Cell-extracellular matrix interactions","_row":"REACT_20649"} {"Pathway":"REACT_267863","Pathway_name":"Defective MAOA causes Brunner syndrome (BRUNS)","_row":"REACT_267863"} {"Pathway":"REACT_15548","Pathway_name":"Enzymatic degradation of dopamine by COMT","_row":"REACT_15548"} {"Pathway":"REACT_15511","Pathway_name":"Enzymatic degradation of Dopamine by monoamine oxidase","_row":"REACT_15511"} {"Pathway":"REACT_416","Pathway_name":"Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB","_row":"REACT_416"} {"Pathway":"REACT_264271","Pathway_name":"Toxicity of botulinum toxin type G (BoNT/G)","_row":"REACT_264271"} {"Pathway":"REACT_14805","Pathway_name":"Interconversion of polyamines","_row":"REACT_14805"} {"Pathway":"REACT_18425","Pathway_name":"Prostanoid ligand receptors","_row":"REACT_18425"} {"Pathway":"REACT_121255","Pathway_name":"Signaling by FGFR2 amplification mutants","_row":"REACT_121255"} {"Pathway":"REACT_164006","Pathway_name":"Sperm:Oocyte Membrane Binding","_row":"REACT_164006"} {"Pathway":"REACT_169313","Pathway_name":"Defective MUT causes methylmalonic aciduria mut type","_row":"REACT_169313"} {"Pathway":"REACT_169316","Pathway_name":"Defective MMAA causes methylmalonic aciduria type cblA","_row":"REACT_169316"} {"Pathway":"REACT_147734","Pathway_name":"MPS II - Hunter syndrome","_row":"REACT_147734"} {"Pathway":"REACT_268058","Pathway_name":"Defective UGT1A1 causes hyperbilirubinemia","_row":"REACT_268058"} {"Pathway":"REACT_268618","Pathway_name":"Defective UGT1A4 causes hyperbilirubinemia","_row":"REACT_268618"} {"Pathway":"REACT_121286","Pathway_name":"FGFR4 mutant receptor activation","_row":"REACT_121286"} {"Pathway":"REACT_121011","Pathway_name":"t(4;14) translocations of FGFR3","_row":"REACT_121011"} {"Pathway":"REACT_19281","Pathway_name":"Class II GLUTs","_row":"REACT_19281"} {"Pathway":"REACT_1396","Pathway_name":"COX reactions","_row":"REACT_1396"} {"Pathway":"REACT_6754","Pathway_name":"S6K1-mediated signalling","_row":"REACT_6754"} {"Pathway":"REACT_268587","Pathway_name":"Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)","_row":"REACT_268587"} {"Pathway":"REACT_115639","Pathway_name":"Sulfur amino acid metabolism","_row":"REACT_115639"} {"Pathway":"REACT_263857","Pathway_name":"Toxicity of botulinum toxin type F (BoNT/F)","_row":"REACT_263857"} {"Pathway":"REACT_1477","Pathway_name":"Eukaryotic Translation Elongation","_row":"REACT_1477"} {"Pathway":"REACT_268528","Pathway_name":"Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)","_row":"REACT_268528"} {"Pathway":"REACT_1464","Pathway_name":"Synthesis of Ketone Bodies","_row":"REACT_1464"} {"Pathway":"REACT_59","Pathway_name":"Utilization of Ketone Bodies","_row":"REACT_59"} {"Pathway":"REACT_16903","Pathway_name":"Histamine receptors","_row":"REACT_16903"} {"Pathway":"REACT_107","Pathway_name":"Apoptotic cleavage of cellular proteins","_row":"REACT_107"} {"Pathway":"REACT_263859","Pathway_name":"APC truncation mutants are not K63 polyubiquitinated","_row":"REACT_263859"} {"Pathway":"REACT_2148","Pathway_name":"Switching of origins to a post-replicative state","_row":"REACT_2148"} {"Pathway":"REACT_900","Pathway_name":"FasL/ CD95L signaling","_row":"REACT_900"} {"Pathway":"REACT_25210","Pathway_name":"N-glycan trimming and elongation in the cis-Golgi","_row":"REACT_25210"} {"Pathway":"REACT_25064","Pathway_name":"Tristetraprolin (TTP) destabilizes mRNA","_row":"REACT_25064"} {"Pathway":"REACT_169415","Pathway_name":"Defective GIF causes intrinsic factor deficiency","_row":"REACT_169415"} {"Pathway":"REACT_355289","Pathway_name":"Signaling by FGFR1","_row":"REACT_355289"} {"Pathway":"REACT_12436","Pathway_name":"ERKs are inactivated","_row":"REACT_12436"} {"Pathway":"REACT_355200","Pathway_name":"Signaling by FGFR2","_row":"REACT_355200"} {"Pathway":"REACT_252852","Pathway_name":"Signaling by FGFR3","_row":"REACT_252852"} {"Pathway":"REACT_355408","Pathway_name":"Signaling by FGFR4","_row":"REACT_355408"} {"Pathway":"REACT_1893","Pathway_name":"Resolution of Abasic Sites (AP sites)","_row":"REACT_1893"} {"Pathway":"REACT_735","Pathway_name":"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA","_row":"REACT_735"} {"Pathway":"REACT_2108","Pathway_name":"Beta oxidation of myristoyl-CoA to lauroyl-CoA","_row":"REACT_2108"} {"Pathway":"REACT_15466","Pathway_name":"phospho-PLA2 pathway","_row":"REACT_15466"} {"Pathway":"REACT_11050","Pathway_name":"Transport of connexons to the plasma membrane","_row":"REACT_11050"} {"Pathway":"REACT_18288","Pathway_name":"Adenosine P1 receptors","_row":"REACT_18288"} {"Pathway":"REACT_939","Pathway_name":"Insulin effects increased synthesis of Xylulose-5-Phosphate","_row":"REACT_939"} {"Pathway":"REACT_12510","Pathway_name":"NOSIP mediated eNOS trafficking","_row":"REACT_12510"} {"Pathway":"REACT_1505","Pathway_name":"Integration of energy metabolism","_row":"REACT_1505"} {"Pathway":"REACT_2160","Pathway_name":"p53-Independent DNA Damage Response","_row":"REACT_2160"} {"Pathway":"REACT_23910","Pathway_name":"Reuptake of GABA","_row":"REACT_23910"} {"Pathway":"REACT_268486","Pathway_name":"Defective FMO3 causes Trimethylaminuria (TMAU)","_row":"REACT_268486"} {"Pathway":"REACT_13653","Pathway_name":"FMO oxidises nucleophiles","_row":"REACT_13653"} {"Pathway":"REACT_13655","Pathway_name":"AKT-mediated inactivation of FOXO1A","_row":"REACT_13655"} {"Pathway":"REACT_24915","Pathway_name":"Butyrate Response Factor 1 (BRF1) destabilizes mRNA","_row":"REACT_24915"} {"Pathway":"REACT_6743","Pathway_name":"Inhibition of TSC complex formation by PKB","_row":"REACT_6743"} {"Pathway":"REACT_1451","Pathway_name":"PDE3B signalling","_row":"REACT_1451"} {"Pathway":"REACT_115654","Pathway_name":"Degradation of cysteine and homocysteine","_row":"REACT_115654"} {"Pathway":"REACT_115589","Pathway_name":"Cysteine formation from homocysteine","_row":"REACT_115589"} {"Pathway":"REACT_355321","Pathway_name":"RHO GTPases activate KTN1","_row":"REACT_355321"} {"Pathway":"REACT_147825","Pathway_name":"MPS IV - Morquio syndrome A","_row":"REACT_147825"} {"Pathway":"REACT_163743","Pathway_name":"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production","_row":"REACT_163743"} {"Pathway":"REACT_264567","Pathway_name":"repression of WNT target genes","_row":"REACT_264567"} {"Pathway":"REACT_11213","Pathway_name":"Nicotinamide salvaging","_row":"REACT_11213"} {"Pathway":"REACT_147857","Pathway_name":"MPS I - Hurler syndrome","_row":"REACT_147857"} {"Pathway":"REACT_120919","Pathway_name":"Synthesis of PE","_row":"REACT_120919"} {"Pathway":"REACT_16970","Pathway_name":"Electric Transmission Across Gap Junctions","_row":"REACT_16970"} {"Pathway":"REACT_150237","Pathway_name":"Phosphate bond hydrolysis by NUDT proteins","_row":"REACT_150237"} {"Pathway":"REACT_163796","Pathway_name":"Interaction With Cumulus Cells","_row":"REACT_163796"} {"Pathway":"REACT_21346","Pathway_name":"Activation of Ca-permeable Kainate Receptor","_row":"REACT_21346"} {"Pathway":"REACT_21343","Pathway_name":"Activation of Na-permeable Kainate Receptors","_row":"REACT_21343"} {"Pathway":"REACT_19357","Pathway_name":"Multifunctional anion exchangers","_row":"REACT_19357"} {"Pathway":"REACT_2025","Pathway_name":"Beta oxidation of palmitoyl-CoA to myristoyl-CoA","_row":"REACT_2025"} {"Pathway":"REACT_264533","Pathway_name":"WNT5A-dependent internalization of FZD2, FZD5 and ROR2","_row":"REACT_264533"} {"Pathway":"REACT_167","Pathway_name":"mRNA Editing: C to U Conversion","_row":"REACT_167"} {"Pathway":"REACT_1390","Pathway_name":"Formation of the Editosome","_row":"REACT_1390"} {"Pathway":"REACT_163734","Pathway_name":"STAT6-mediated induction of chemokines","_row":"REACT_163734"} {"Pathway":"REACT_18338","Pathway_name":"Activation of AMPA receptors","_row":"REACT_18338"} {"Pathway":"REACT_6838","Pathway_name":"mTOR signalling","_row":"REACT_6838"} {"Pathway":"REACT_121168","Pathway_name":"Synthesis of PIPs at the ER membrane","_row":"REACT_121168"} {"Pathway":"REACT_13532","Pathway_name":"Stimulation of the cell death response by PAK-2p34","_row":"REACT_13532"} {"Pathway":"REACT_2190","Pathway_name":"SMAC binds to IAPs ","_row":"REACT_2190"} {"Pathway":"REACT_1767","Pathway_name":"SMAC-mediated dissociation of IAP:caspase complexes ","_row":"REACT_1767"} {"Pathway":"REACT_169403","Pathway_name":"Defective BTD causes biotidinase deficiency","_row":"REACT_169403"} {"Pathway":"REACT_22279","Pathway_name":"Fatty acid, triacylglycerol, and ketone body metabolism","_row":"REACT_22279"} {"Pathway":"REACT_2100","Pathway_name":"Activation of BMF and translocation to mitochondria","_row":"REACT_2100"} {"Pathway":"REACT_19328","Pathway_name":"Proton/oligonucleotide cotransporters","_row":"REACT_19328"} {"Pathway":"REACT_14835","Pathway_name":"Notch-HLH transcription pathway","_row":"REACT_14835"} {"Pathway":"REACT_118722","Pathway_name":"Pre-NOTCH Processing in the Endoplasmic Reticulum","_row":"REACT_118722"} {"Pathway":"REACT_160305","Pathway_name":"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling","_row":"REACT_160305"} {"Pathway":"REACT_147851","Pathway_name":"Arachidonic acid metabolism","_row":"REACT_147851"} {"Pathway":"REACT_75815","Pathway_name":"Potassium transport channels","_row":"REACT_75815"} {"Pathway":"REACT_75870","Pathway_name":"Classical Kir channels","_row":"REACT_75870"} {"Pathway":"REACT_264321","Pathway_name":"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation","_row":"REACT_264321"} {"Pathway":"REACT_268321","Pathway_name":"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)","_row":"REACT_268321"} {"Pathway":"REACT_267887","Pathway_name":"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)","_row":"REACT_267887"} {"Pathway":"REACT_120823","Pathway_name":"Synthesis of PS","_row":"REACT_120823"} {"Pathway":"REACT_121079","Pathway_name":"PI and PC transport between ER and Golgi membranes","_row":"REACT_121079"} {"Pathway":"REACT_163785","Pathway_name":"Hydroxycarboxylic acid-binding receptors","_row":"REACT_163785"} {"Pathway":"REACT_25046","Pathway_name":"Transport to the Golgi and subsequent modification","_row":"REACT_25046"} {"Pathway":"REACT_1319","Pathway_name":"Fatty Acyl-CoA Biosynthesis","_row":"REACT_1319"} {"Pathway":"REACT_11172","Pathway_name":"Vitamin B5 (pantothenate) metabolism","_row":"REACT_11172"} {"Pathway":"REACT_12469","Pathway_name":"Hypusine synthesis from eIF5A-lysine","_row":"REACT_12469"} {"Pathway":"REACT_25302","Pathway_name":"Reactions specific to the complex N-glycan synthesis pathway","_row":"REACT_25302"} {"Pathway":"REACT_15297","Pathway_name":"Regulation of thyroid hormone activity","_row":"REACT_15297"} {"Pathway":"REACT_355167","Pathway_name":"Essential fructosuria","_row":"REACT_355167"} {"Pathway":"REACT_268059","Pathway_name":"Defective SLC26A2 causes chondrodysplasias","_row":"REACT_268059"} {"Pathway":"REACT_23876","Pathway_name":"Platelet homeostasis","_row":"REACT_23876"} {"Pathway":"REACT_162","Pathway_name":"Elevation of cytosolic Ca2+ levels","_row":"REACT_162"} {"Pathway":"REACT_268027","Pathway_name":"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)","_row":"REACT_268027"} {"Pathway":"REACT_23964","Pathway_name":"Degradation of GABA","_row":"REACT_23964"} {"Pathway":"REACT_147753","Pathway_name":"MPS IIIA - Sanfilippo syndrome A","_row":"REACT_147753"} {"Pathway":"REACT_1016","Pathway_name":"Mitotic Metaphase/Anaphase Transition","_row":"REACT_1016"} {"Pathway":"REACT_22230","Pathway_name":"Synthesis of Dolichyl-phosphate","_row":"REACT_22230"} {"Pathway":"REACT_476","Pathway_name":"DNA Damage Recognition in GG-NER","_row":"REACT_476"} {"Pathway":"REACT_15408","Pathway_name":"Cam-PDE 1 activation","_row":"REACT_15408"} {"Pathway":"REACT_147788","Pathway_name":"MPS IIIB - Sanfilippo syndrome B","_row":"REACT_147788"} {"Pathway":"REACT_19315","Pathway_name":"Cation-coupled Chloride cotransporters","_row":"REACT_19315"} {"Pathway":"REACT_1966","Pathway_name":"Formation of editosomes by ADAR proteins","_row":"REACT_1966"} {"Pathway":"REACT_1231","Pathway_name":"C6 deamination of adenosine","_row":"REACT_1231"} {"Pathway":"REACT_163725","Pathway_name":"SUMO is proteolytically processed","_row":"REACT_163725"} {"Pathway":"REACT_163812","Pathway_name":"SUMO is conjugated to E1 (UBA2:SAE1)","_row":"REACT_163812"} {"Pathway":"REACT_163646","Pathway_name":"SUMO is transferred from E1 to E2 (UBE2I, UBC9)","_row":"REACT_163646"} {"Pathway":"REACT_584","Pathway_name":"Activation, translocation and oligomerization of BAX","_row":"REACT_584"} {"Pathway":"REACT_707","Pathway_name":"Activation and oligomerization of BAK protein","_row":"REACT_707"} {"Pathway":"REACT_264499","Pathway_name":"TCF7L2 mutants don't bind CTBP","_row":"REACT_264499"} {"Pathway":"REACT_355467","Pathway_name":"PTEN Loss of Function in Cancer","_row":"REACT_355467"} {"Pathway":"REACT_264227","Pathway_name":"Toxicity of botulinum toxin type E (BoNT/E)","_row":"REACT_264227"} {"Pathway":"REACT_9053","Pathway_name":"CaM pathway","_row":"REACT_9053"} {"Pathway":"REACT_20652","Pathway_name":"Activation of CaMK IV","_row":"REACT_20652"} {"Pathway":"REACT_22151","Pathway_name":"Transport of nucleotide sugars","_row":"REACT_22151"} {"Pathway":"REACT_169107","Pathway_name":"SMAD4 MH2 Domain Mutants in Cancer","_row":"REACT_169107"} {"Pathway":"REACT_1322","Pathway_name":"Release of apoptotic factors from the mitochondria","_row":"REACT_1322"} {"Pathway":"REACT_268063","Pathway_name":"Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)","_row":"REACT_268063"} {"Pathway":"REACT_15514","Pathway_name":"Dopamine clearance from the synaptic cleft","_row":"REACT_15514"} {"Pathway":"REACT_20508","Pathway_name":"Rhesus glycoproteins mediate ammonium transport.","_row":"REACT_20508"} {"Pathway":"REACT_268413","Pathway_name":"Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)","_row":"REACT_268413"} {"Pathway":"REACT_267633","Pathway_name":"Defective ACY1 causes encephalopathy","_row":"REACT_267633"} {"Pathway":"REACT_24020","Pathway_name":"GABA synthesis","_row":"REACT_24020"} {"Pathway":"REACT_20619","Pathway_name":"mRNA decay by 3' to 5' exoribonuclease","_row":"REACT_20619"} {"Pathway":"REACT_268803","Pathway_name":"Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)","_row":"REACT_268803"} {"Pathway":"REACT_19275","Pathway_name":"Sodium-coupled phosphate cotransporters","_row":"REACT_19275"} {"Pathway":"REACT_6800","Pathway_name":"Conjugation of phenylacetate with glutamine","_row":"REACT_6800"} {"Pathway":"REACT_6933","Pathway_name":"Conjugation of benzoate with glycine","_row":"REACT_6933"} {"Pathway":"REACT_25266","Pathway_name":"Reactions specific to the hybrid N-glycan synthesis pathway","_row":"REACT_25266"} {"Pathway":"REACT_268600","Pathway_name":"Defective MGAT2 causes MGAT2-CDG (CDG-2a)","_row":"REACT_268600"} {"Pathway":"REACT_147739","Pathway_name":"MPS IX - Natowicz syndrome","_row":"REACT_147739"} {"Pathway":"REACT_1041","Pathway_name":"Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components","_row":"REACT_1041"} {"Pathway":"REACT_12020","Pathway_name":"Signalling to ERK5","_row":"REACT_12020"} {"Pathway":"REACT_20646","Pathway_name":"Sodium-coupled sulphate, di- and tri-carboxylate transporters","_row":"REACT_20646"} {"Pathway":"REACT_491","Pathway_name":"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal","_row":"REACT_491"} {"Pathway":"REACT_18302","Pathway_name":"Leukotriene receptors","_row":"REACT_18302"} {"Pathway":"REACT_204","Pathway_name":"ATM mediated response to DNA double-strand break","_row":"REACT_204"} {"Pathway":"REACT_19305","Pathway_name":"Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds","_row":"REACT_19305"} {"Pathway":"REACT_20603","Pathway_name":"Zinc influx into cells by the SLC39 gene family","_row":"REACT_20603"} {"Pathway":"REACT_267905","Pathway_name":"Defective MOGS causes MOGS-CDG (CDG-2b)","_row":"REACT_267905"} {"Pathway":"REACT_118811","Pathway_name":"IRF3 mediated activation of type 1 IFN","_row":"REACT_118811"} {"Pathway":"REACT_19372","Pathway_name":"Organic anion transporters","_row":"REACT_19372"} {"Pathway":"REACT_9047","Pathway_name":"Toll Like Receptor 9 (TLR9) Cascade","_row":"REACT_9047"} {"Pathway":"REACT_13438","Pathway_name":"Sterols are 12-hydroxylated by CYP8B1","_row":"REACT_13438"} {"Pathway":"REACT_121226","Pathway_name":"Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha","_row":"REACT_121226"} {"Pathway":"REACT_268087","Pathway_name":"Defective CYP1B1 causes Glaucoma","_row":"REACT_268087"} {"Pathway":"REACT_268132","Pathway_name":"Defective ALG11 causes ALG11-CDG (CDG-1p)","_row":"REACT_268132"} {"Pathway":"REACT_19348","Pathway_name":"Proton-coupled neutral amino acid transporters","_row":"REACT_19348"} {"Pathway":"REACT_22310","Pathway_name":"Organic anion transport","_row":"REACT_22310"} {"Pathway":"REACT_160111","Pathway_name":"Ubiquinol biosynthesis","_row":"REACT_160111"} {"Pathway":"REACT_147860","Pathway_name":"MPS IIIC - Sanfilippo syndrome C","_row":"REACT_147860"} {"Pathway":"REACT_160194","Pathway_name":"Biosynthesis of A2E, implicated in retinal degradation","_row":"REACT_160194"} {"Pathway":"REACT_526","Pathway_name":"ALKBH2 mediated reversal of alkylation damage","_row":"REACT_526"} {"Pathway":"REACT_268441","Pathway_name":"Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)","_row":"REACT_268441"} {"Pathway":"REACT_20582","Pathway_name":"Zinc efflux and compartmentalization by the SLC30 family","_row":"REACT_20582"} {"Pathway":"REACT_505","Pathway_name":"PAOs oxidise polyamines to amines","_row":"REACT_505"} {"Pathway":"REACT_267734","Pathway_name":"Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)","_row":"REACT_267734"} {"Pathway":"REACT_268491","Pathway_name":"Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)","_row":"REACT_268491"} {"Pathway":"REACT_75801","Pathway_name":"TWIK-related spinal cord K+ channel (TRESK)","_row":"REACT_75801"} {"Pathway":"REACT_268326","Pathway_name":"Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)","_row":"REACT_268326"} {"Pathway":"REACT_25367","Pathway_name":"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate","_row":"REACT_25367"} {"Pathway":"REACT_1662","Pathway_name":"ALKBH3 mediated reversal of alkylation damage","_row":"REACT_1662"} {"Pathway":"REACT_19308","Pathway_name":"Arachidonate production from DAG","_row":"REACT_19308"} {"Pathway":"REACT_118699","Pathway_name":"Post-transcriptional silencing by small RNAs","_row":"REACT_118699"} {"Pathway":"REACT_150275","Pathway_name":"Synthesis of IPs in the nucleus","_row":"REACT_150275"} {"Pathway":"REACT_18352","Pathway_name":"Eicosanoid ligand-binding receptors","_row":"REACT_18352"} {"Pathway":"REACT_25091","Pathway_name":"ER Quality Control Compartment (ERQC)","_row":"REACT_25091"} {"Pathway":"REACT_268185","Pathway_name":"Defective ALG3 causes ALG3-CDG (CDG-1d)","_row":"REACT_268185"} {"Pathway":"REACT_14800","Pathway_name":"Agmatine biosynthesis","_row":"REACT_14800"} {"Pathway":"REACT_268458","Pathway_name":"Defective RFT1 causes RFT1-CDG (CDG-1n)","_row":"REACT_268458"} {"Pathway":"REACT_169318","Pathway_name":"Defective MMAB causes methylmalonic aciduria type cblB","_row":"REACT_169318"} {"Pathway":"REACT_268645","Pathway_name":"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)","_row":"REACT_268645"} {"Pathway":"REACT_75850","Pathway_name":"TWIK-related alkaline pH activated K+ channel (TALK)","_row":"REACT_75850"} {"Pathway":"REACT_610","Pathway_name":"Mitochondrial transcription termination","_row":"REACT_610"} {"Pathway":"REACT_169149","Pathway_name":"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG","_row":"REACT_169149"} {"Pathway":"REACT_169439","Pathway_name":"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE","_row":"REACT_169439"} {"Pathway":"REACT_1132","Pathway_name":"Gamma-carboxylation, transport, and amino-terminal cleavage of proteins","_row":"REACT_1132"} {"Pathway":"REACT_268144","Pathway_name":"Defective ALG1 causes ALG1-CDG (CDG-1k)","_row":"REACT_268144"} {"Pathway":"REACT_267773","Pathway_name":"Defective ALG12 causes ALG12-CDG (CDG-1g)","_row":"REACT_267773"} {"Pathway":"REACT_268459","Pathway_name":"Defective ALG8 causes ALG8-CDG (CDG-1h)","_row":"REACT_268459"} {"Pathway":"REACT_1763","Pathway_name":"Homologous DNA pairing and strand exchange","_row":"REACT_1763"} {"Pathway":"REACT_9027","Pathway_name":"Toll Like Receptor 10 (TLR10) Cascade","_row":"REACT_9027"} {"Pathway":"REACT_1698","Pathway_name":"Metabolism of nucleotides","_row":"REACT_1698"} {"Pathway":"REACT_118764","Pathway_name":"ZBP1(DAI) mediated induction of type I IFNs","_row":"REACT_118764"} {"Pathway":"REACT_13781","Pathway_name":"Trafficking of dietary sterols","_row":"REACT_13781"} {"Pathway":"REACT_263933","Pathway_name":"WNT ligand secretion is abrogated by the PORCN inhibitor LGK974","_row":"REACT_263933"} {"Pathway":"REACT_268849","Pathway_name":"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2","_row":"REACT_268849"} {"Pathway":"REACT_169256","Pathway_name":"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD","_row":"REACT_169256"} {"Pathway":"REACT_268833","Pathway_name":"Defective ALG2 causes ALG2-CDG (CDG-1i)","_row":"REACT_268833"} {"Pathway":"REACT_268015","Pathway_name":"Defective ALG9 causes ALG9-CDG (CDG-1l)","_row":"REACT_268015"} {"Pathway":"REACT_75880","Pathway_name":"Tandem pore domain halothane-inhibited K+ channel (THIK)","_row":"REACT_75880"} {"Pathway":"REACT_120785","Pathway_name":"Hydrolysis of LPE","_row":"REACT_120785"} {"Pathway":"REACT_268108","Pathway_name":"Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)","_row":"REACT_268108"} {"Pathway":"REACT_9020","Pathway_name":"Toll Like Receptor 7/8 (TLR7/8) Cascade","_row":"REACT_9020"} {"Pathway":"REACT_163652","Pathway_name":"Regulation by TREX1","_row":"REACT_163652"} {"Pathway":"REACT_267818","Pathway_name":"Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)","_row":"REACT_267818"} {"Pathway":"REACT_169363","Pathway_name":"Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF","_row":"REACT_169363"} {"Pathway":"REACT_120920","Pathway_name":"Synthesis of CL","_row":"REACT_120920"} {"Pathway":"REACT_268813","Pathway_name":"Defective MAN1B1 causes MRT15","_row":"REACT_268813"} {"Pathway":"REACT_150253","Pathway_name":"Synthesis of IPs in the ER lumen","_row":"REACT_150253"} {"Pathway":"REACT_169169","Pathway_name":"Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC","_row":"REACT_169169"} {"Pathway":"REACT_267765","Pathway_name":"Defective ALG6 causes ALG6-CDG (CDG-1c)","_row":"REACT_267765"} {"Pathway":"REACT_22346","Pathway_name":"Synthesis of dolichyl-phosphate-glucose","_row":"REACT_22346"}