# ------------------------------------------------ # CITATION.cff file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # ------------------------------------------------ cff-version: 1.2.0 message: 'To cite package "PACE" in publications use:' type: software license: GPL-3.0-only title: 'PACE: Proximity-Associated Changes in Expression for Spatial Transcriptomics' version: 0.99.20 abstract: PACE (Proximity-Associated Changes in Expression) is a hierarchical empirical Bayes framework that quantifies how a cell's gene expression changes with proximity to specific neighbouring cell types in imaging-based spatial transcriptomics such as Xenium and CosMx. It fits negative binomial mixed models with partial pooling across cell types, corrects for transcript contamination between adjacent cells with a per-cell ambient term, and decomposes expression variance into cell-type identity, spatial cell state, contamination, and residual components. Input and output follow SpatialExperiment conventions. authors: - family-names: Willie given-names: Elijah email: ewil3501@uni.sydney.edu.au orcid: https://orcid.org/0000-0002-5773-3649 - family-names: Rao given-names: Shreya Rajesh - family-names: Ormerod given-names: John - family-names: Patrick given-names: Ellis repository: https://bioc.r-universe.dev repository-code: https://github.com/ecool50/PACE commit: 571c2262e6a1d2ddd9c98ccb8f99d028ec149903 url: https://ecool50.github.io/PACE date-released: '2026-10-14' contact: - family-names: Willie given-names: Elijah email: ewil3501@uni.sydney.edu.au orcid: https://orcid.org/0000-0002-5773-3649