Package: MultiRNAflow Title: An R package for integrated analysis of temporal RNA-seq data with multiple biological conditions Version: 1.11.0 Authors@R: c( person("Rodolphe", "Loubaton", , "loubaton.rodolphe@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-1442-7270")), person("Nicolas", "Champagnat", , "nicolas.champagnat@inria.fr", role = c("aut", "ths"), comment = c(ORCID = "0000-0002-5128-2357")), person("Laurent", "Vallat", , "vallat@unistra.fr", role = c("aut", "ths"), comment = c(ORCID = "0000-0002-5226-7706")), person("Pierre", "Vallois", , "pierre.vallois@univ-lorraine.fr", role = "aut", comment = c(ORCID = "0000-0002-2123-0142")), person("Région Grand Est", role = "fnd"), person("Cancéropôle Est", role = "fnd") ) Description: Our R package MultiRNAflow provides an easy to use unified framework allowing to automatically make both unsupervised and supervised (DE) analysis for datasets with an arbitrary number of biological conditions and time points. In particular, our code makes a deep downstream analysis of DE information, e.g. identifying temporal patterns across biological conditions and DE genes which are specific to a biological condition for each time. License: GPL-3 | file LICENSE URL: https://github.com/loubator/MultiRNAflow BugReports: https://github.com/loubator/MultiRNAflow/issues Depends: Mfuzz (>= 2.64.0), R (>= 4.4) Imports: Biobase (>= 2.54.0), ComplexHeatmap (>= 2.20.0), DESeq2 (>= 1.44.0), factoextra (>= 1.0.7), FactoMineR (>= 2.11), ggalluvial (>= 0.12.5), ggplot2 (>= 3.5.1), ggplotify (>= 0.1.2), ggrepel (>= 0.9.5), gprofiler2 (>= 0.2.3), graphics (>= 4.2.2), grDevices (>= 4.2.2), grid (>= 4.2.2), plot3D (>= 1.4.1), plot3Drgl (>= 1.0.4), reshape2 (>= 1.4.4), rlang (>= 1.1.6), S4Vectors (>= 0.42.0), stats (>= 4.2.2), SummarizedExperiment (>= 1.34.0), UpSetR (>= 1.4.0), utils (>= 4.2.2) Suggests: BiocGenerics (>= 0.40.0), BiocStyle (>= 2.32.1), e1071 (>= 1.7.12), knitr (>= 1.47), rmarkdown (>= 2.27), testthat (>= 3.0.0) VignetteBuilder: knitr biocViews: Sequencing, RNASeq, GeneExpression, Transcription, TimeCourse, Preprocessing, Visualization, Normalization, PrincipalComponent, Clustering, DifferentialExpression, GeneSetEnrichment, Pathways Config/testthat/edition: 3 Encoding: UTF-8 LazyData: false Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Config/pak/sysreqs: cmake libfreetype6-dev libglu1-mesa-dev make texlive libicu-dev libjpeg-dev libpng-dev libuv1-dev libxml2-dev libgl1-mesa-dev libssl-dev perl zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:01:24 UTC RemoteUrl: https://github.com/bioc/MultiRNAflow RemoteRef: HEAD RemoteSha: 85573fdb98f471c3ec087d737f84a3b0f5718b57 NeedsCompilation: no Packaged: 2026-07-04 23:23:17 UTC; root Author: Rodolphe Loubaton [aut, cre] (ORCID: ), Nicolas Champagnat [aut, ths] (ORCID: ), Laurent Vallat [aut, ths] (ORCID: ), Pierre Vallois [aut] (ORCID: ), Région Grand Est [fnd], Cancéropôle Est [fnd] Maintainer: Rodolphe Loubaton