Package: Modstrings Type: Package Title: Working with modified nucleotide sequences Version: 1.29.0 Date: 2022-12-24 Authors@R: c(person("Felix G.M.", "Ernst", email = "felix.gm.ernst@outlook.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-5064-0928")), person("Denis L.J.", "Lafontaine", email = "denis.lafontaine@ulb.ac.be", role = c("ctb", "fnd"))) Description: Representing nucleotide modifications in a nucleotide sequence is usually done via special characters from a number of sources. This represents a challenge to work with in R and the Biostrings package. The Modstrings package implements this functionallity for RNA and DNA sequences containing modified nucleotides by translating the character internally in order to work with the infrastructure of the Biostrings package. For this the ModRNAString and ModDNAString classes and derivates and functions to construct and modify these objects despite the encoding issues are implemenented. In addition the conversion from sequences to list like location information (and the reverse operation) is implemented as well. License: Artistic-2.0 Encoding: UTF-8 biocViews: DataImport, DataRepresentation, Infrastructure, Sequencing, Software Depends: R (>= 3.6), Biostrings (>= 2.79.3) Imports: methods, BiocGenerics, GenomicRanges, S4Vectors, IRanges, XVector, stringi, stringr, crayon, grDevices Suggests: BiocStyle, knitr, rmarkdown, testthat, usethis Collate: 'Modstrings.R' 'AllGenerics.R' 'Modstrings-external-functions.R' 'Modstrings-external-C-calls.R' 'Modstrings-ModStringCodec.R' 'Modstrings-ModString.R' 'Modstrings-ModStringSet.R' 'Modstrings-ModStringViews.R' 'Modstrings-MaskedModString.R' 'Modstrings-ModStringCodec-data.R' 'Modstrings-ModStringSet-io.R' 'Modstrings-ModStringSetList.R' 'Modstrings-QualityScaledModStringSet.R' 'Modstrings-letterFrequency.R' 'Modstrings-modifyNucleotide.R' 'Modstrings-replaceLetterAt.R' 'Modstrings-sanitize.R' 'Modstrings-separate.R' 'Modstrings-seqtype.R' 'datasets.R' 'utils.R' 'zzz.R' VignetteBuilder: knitr RoxygenNote: 7.3.3 BugReports: https://github.com/FelixErnst/Modstrings/issues Config/pak/sysreqs: libicu-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:49:42 UTC RemoteUrl: https://github.com/bioc/Modstrings RemoteRef: HEAD RemoteSha: 4509228b0af0b505d0a14a5f87fa28996a89f553 NeedsCompilation: no Packaged: 2026-07-04 07:02:55 UTC; root Author: Felix G.M. Ernst [aut, cre] (ORCID: ), Denis L.J. Lafontaine [ctb, fnd] Maintainer: Felix G.M. Ernst