Package: MeLSI
Type: Package
Title: Metric Learning for Statistical Inference in Microbiome Analysis
Version: 1.1.7
Authors@R: c(person("Nathan", "Bresette", email = "nathanbresette04@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0009-0003-1554-6006")), person("Aaron C.", "Ericsson", role = "aut", comment = c(ORCID = "0000-0002-3053-7269")), person("Carter", "Woods", role = "aut", comment = c(ORCID = "0009-0007-5345-2712")), person("Ai-Ling", "Lin", role = c("aut", "fnd"), comment = c(ORCID = "0000-0002-5197-2219")))
Description: MeLSI (Metric Learning for Statistical Inference) is a
        novel machine learning method for microbiome data analysis that
        learns optimal distance metrics to improve statistical power in
        detecting group differences. Unlike traditional distance
        metrics (Bray-Curtis, Euclidean, Jaccard), MeLSI adapts to the
        specific characteristics of your dataset to maximize separation
        between groups. The method uses an ensemble of weak learners to
        identify which microbial features drive group differences,
        providing both improved statistical power and biological
        interpretability through feature importance weights.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.3.3
Depends: R (>= 4.5.0)
URL: https://github.com/NathanBresette/MeLSI
BugReports: https://github.com/NathanBresette/MeLSI/issues
Imports: ggplot2, stats, utils, Rcpp
LinkingTo: Rcpp
Suggests: testthat, knitr, rmarkdown, BiocManager, BiocStyle,
        BiocParallel, Matrix, microbiome, phyloseq, vegan
VignetteBuilder: knitr
biocViews: Software, StatisticalMethod, Microbiome
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-06-17 21:23:49 UTC
RemoteUrl: https://github.com/bioc/MeLSI
RemoteRef: HEAD
RemoteSha: 19902ee27eb55b11d471d7afb62c7e53eccba723
NeedsCompilation: yes
Packaged: 2026-07-18 08:47:04 UTC; root
Author: Nathan Bresette [aut, cre] (ORCID:
    <https://orcid.org/0009-0003-1554-6006>),
  Aaron C. Ericsson [aut] (ORCID:
    <https://orcid.org/0000-0002-3053-7269>),
  Carter Woods [aut] (ORCID: <https://orcid.org/0009-0007-5345-2712>),
  Ai-Ling Lin [aut, fnd] (ORCID: <https://orcid.org/0000-0002-5197-2219>)
Maintainer: Nathan Bresette <nathanbresette04@gmail.com>