Package: Macarron
Version: 1.17.0
Title: Prioritization of potentially bioactive metabolic features from
        epidemiological and environmental metabolomics datasets
Authors@R: c(
  person("Amrisha", "Bhosle", email = "amrishabhosle@gmail.com", role = "aut"), 
  person("Ludwig", "Geistlinger", email = "Ludwig_Geistlinger@hms.harvard.edu", role = "aut"),
  person("Sagun", "Maharjan", email = "sagunmaharjann@gmail.com", role = c("aut", "cre"))
  )
Depends: R (>= 4.5.0), SummarizedExperiment
Imports: BiocParallel, DelayedArray, WGCNA, ff, data.table,
        dynamicTreeCut, Maaslin2, plyr, stats, psych, logging, methods,
        utils
Suggests: knitr, BiocStyle, optparse, testthat (>= 2.1.0), rmarkdown,
        markdown
Description: Macarron is a workflow for the prioritization of
        potentially bioactive metabolites from metabolomics
        experiments. Prioritization integrates strengths of evidences
        of bioactivity such as covariation with a known metabolite,
        abundance relative to a known metabolite and association with
        an environmental or phenotypic indicator of bioactivity.
        Broadly, the workflow consists of stratified clustering of
        metabolic spectral features which co-vary in abundance in a
        condition, transfer of functional annotations, estimation of
        relative abundance and differential abundance analysis to
        identify associations between features and phenotype/condition.
VignetteBuilder: knitr
License: MIT + file LICENSE
URL: http://huttenhower.sph.harvard.edu/macarron
Encoding: UTF-8
biocViews: Sequencing, Metabolomics, Coverage, FunctionalPrediction,
        Clustering
BugReports: https://forum.biobakery.org/c/microbial-community-profiling/macarron
RoxygenNote: 7.3.3
Config/pak/sysreqs: cmake make libicu-dev libuv1-dev zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:58:20 UTC
RemoteUrl: https://github.com/bioc/Macarron
RemoteRef: HEAD
RemoteSha: 9abb534c5e7039be874bdd89d1645805e23fdcb8
NeedsCompilation: no
Packaged: 2026-07-04 00:01:07 UTC; root
Author: Amrisha Bhosle [aut],
  Ludwig Geistlinger [aut],
  Sagun Maharjan [aut, cre]
Maintainer: Sagun Maharjan <sagunmaharjann@gmail.com>