Package: MSstatsTMT Title: Protein Significance Analysis in shotgun mass spectrometry-based proteomic experiments with tandem mass tag (TMT) labeling Version: 2.21.2 Date: 2026-08-31 Description: The package provides statistical tools for detecting differentially abundant proteins in shotgun mass spectrometry-based proteomic experiments with tandem mass tag (TMT) labeling. It provides multiple functionalities, including aata visualization, protein quantification and normalization, and statistical modeling and inference. Furthermore, it is inter-operable with other data processing tools, such as Proteome Discoverer, MaxQuant, OpenMS and SpectroMine. Authors@R: c(person("Devon", "Kohler", email = "kohler.d@northeastern.edu", role=c("aut")), person("Ting", "Huang", email = "thuang0703@gmail.com", role=c("aut")), person("Meena", "Choi", email = "mnchoi67@gmail.com", role="aut"), person("Mateusz", "Staniak", email = "mtst@mstaniak.pl", role = "aut"), person("Tony", "Wu", email = "wu.anthon@northeastern.edu", role = c("aut","cre")), person("Deril", "Raju", email = "raju.d@northeastern.edu", role = "aut"), person("Sicheng", "Hao", email = "hao.sic@husky.neu.edu", role = "aut"), person("Olga", "Vitek", email = "o.vitek@northeastern.edu", role = "aut")) License: Artistic-2.0 Depends: R (>= 4.2) Imports: limma, lme4, lmerTest, methods, data.table, stats, utils, ggplot2, grDevices, graphics, MSstats, MSstatsConvert, checkmate, plotly, htmltools Suggests: BiocStyle, knitr, rmarkdown, testthat VignetteBuilder: knitr biocViews: ImmunoOncology, MassSpectrometry, Proteomics, Software Encoding: UTF-8 LazyData: true URL: http://msstats.org/msstatstmt/ BugReports: https://groups.google.com/forum/#!forum/msstats Config/roxygen2/version: 8.1.0 Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libssl-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-10-05 19:51:33 UTC RemoteUrl: https://github.com/bioc/MSstatsTMT RemoteRef: HEAD RemoteSha: f49525e0ef614b7fce041032e4e11d9313adfd4e NeedsCompilation: no Packaged: 2026-10-07 08:37:48 UTC; root Author: Devon Kohler [aut], Ting Huang [aut], Meena Choi [aut], Mateusz Staniak [aut], Tony Wu [aut, cre], Deril Raju [aut], Sicheng Hao [aut], Olga Vitek [aut] Maintainer: Tony Wu