Package: MSstatsResponse Type: Package Title: Statistical Methods for Chemoproteomics Dose-Response Analysis Version: 1.3.1 Authors@R: c( person( "Sarah", "Szvetecz", email = "szvetecz.s@northeastern.edu", role = c("aut", "cre")), person( "Tony", "Wu", email = "wu.anton@northeastern.edu", role = c("aut")), person( "Devon", "Kohler", email = "kohler.d@northeastern.edu", role = c("aut")), person( "Olga", "Vitek", email = "o.vitek@northeastern.edu", role = c("aut"))) Description: Tools for detecting drug-protein interactions and estimating IC50 values from chemoproteomics data. Implements semi-parametric isotonic regression, bootstrapping, and curve fitting to evaluate compound effects on protein abundance. URL: https://github.com/Vitek-Lab/MSstatsResponse BugReports: https://github.com/Vitek-Lab/MSstatsResponse/issues License: Artistic-2.0 Encoding: UTF-8 Depends: R (>= 4.5.0) LazyData: false RoxygenNote: 7.3.3 Imports: BiocParallel, ggplot2, dplyr, stats, parallel, data.table, tidyr, stringr, plotly, utils Suggests: MSstats, MSstatsTMT, tidyverse, boot, purrr, gridExtra, knitr, rmarkdown, BiocStyle, testthat VignetteBuilder: knitr Roxygen: list(markdown = TRUE) biocViews: Proteomics, MassSpectrometry, StatisticalMethod, Software, Regression Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libssl-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-07-13 19:14:51 UTC RemoteUrl: https://github.com/bioc/MSstatsResponse RemoteRef: HEAD RemoteSha: 08261c01cec921c7056525cff5270d3fb9d455c7 NeedsCompilation: no Packaged: 2026-07-13 21:40:45 UTC; root Author: Sarah Szvetecz [aut, cre], Tony Wu [aut], Devon Kohler [aut], Olga Vitek [aut] Maintainer: Sarah Szvetecz