Type: Package
Package: MSstatsLOBD
Title: Assay characterization: estimation of limit of blanc(LoB) and
        limit of detection(LOD)
Version: 1.21.0
Date: 2021-04-12
Description: The MSstatsLOBD package allows calculation and
        visualization of limit of blac (LOB) and limit of detection
        (LOD). We define the LOB as the highest apparent concentration
        of a peptide expected when replicates of a blank sample
        containing no peptides are measured. The LOD is defined as the
        measured concentration value for which the probability of
        falsely claiming the absence of a peptide in the sample is
        0.05, given a probability 0.05 of falsely claiming its
        presence. These functionalities were previously a part of the
        MSstats package. The methodology is described in Galitzine
        (2018) <doi:10.1074/mcp.RA117.000322>.
Authors@R: c(person("Devon", "Kohler", email = "kohler.d@northeastern.edu", role = c("aut", "cre")),
            person("Mateusz", "Staniak", email = "mtst@mstaniak.pl", role = c("aut")),
            person("Cyril", "Galitzine", email = "cyrildgg@gmail.com", role = "aut"),
          	person("Meena", "Choi", email = "mnchoi67@gmail.com", role="aut"),
          	person("Olga", "Vitek", email = "o.vitek@northeastern.edu", role = "aut"))
License: Artistic-2.0
Depends: R (>= 4.0)
Imports: minpack.lm, ggplot2, utils, stats, grDevices
Suggests: BiocStyle, knitr, rmarkdown, covr, tinytest, dplyr
LinkingTo: Rcpp
VignetteBuilder: knitr
biocViews: ImmunoOncology, MassSpectrometry, Proteomics, Software,
        DifferentialExpression, OneChannel, TwoChannel, Normalization,
        QualityControl
BugReports: https://github.com/Vitek-Lab/MSstatsLODQ/issues
Encoding: UTF-8
LazyData: TRUE
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.1
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:56:14 UTC
RemoteUrl: https://github.com/bioc/MSstatsLOBD
RemoteRef: HEAD
RemoteSha: 7c554880e0a8630e754ffa280ec71a69be20c1f5
NeedsCompilation: no
Packaged: 2026-07-10 06:34:30 UTC; root
Author: Devon Kohler [aut, cre],
  Mateusz Staniak [aut],
  Cyril Galitzine [aut],
  Meena Choi [aut],
  Olga Vitek [aut]
Maintainer: Devon Kohler <kohler.d@northeastern.edu>