Package: MIRit Title: Integrate microRNA and gene expression to decipher pathway complexity Version: 1.9.0 Date: 2023-11-23 Authors@R: c( person("Jacopo", "Ronchi", email = "jacopo.ronchi@unimib.it", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-5520-4631")), person("Maria", "Foti", email = "maria.foti@unimib.it", role = c("fnd"), comment = c(ORCID = "0000-0002-4481-1900"))) Description: MIRit is an R package that provides several methods for investigating the relationships between miRNAs and genes in different biological conditions. In particular, MIRit allows to explore the functions of dysregulated miRNAs, and makes it possible to identify miRNA-gene regulatory axes that control biological pathways, thus enabling the users to unveil the complexity of miRNA biology. MIRit is an all-in-one framework that aims to help researchers in all the central aspects of an integrative miRNA-mRNA analyses, from differential expression analysis to network characterization. License: GPL (>= 3) URL: https://jacopo-ronchi.github.io/MIRit/, https://github.com/jacopo-ronchi/MIRit BugReports: https://github.com/jacopo-ronchi/MIRit/issues biocViews: Software, GeneRegulation, NetworkEnrichment, NetworkInference, Epigenetics, FunctionalGenomics, SystemsBiology, Network, Pathways, GeneExpression, DifferentialExpression Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Imports: AnnotationDbi, BiocFileCache, BiocParallel, DESeq2, edgeR, fgsea, genekitr, geneset, ggplot2, ggpubr, graph, graphics, graphite, grDevices, httr, limma, methods, Rcpp, Rgraphviz (>= 2.44.0), rlang, stats, utils Collate: 'AllGenerics.R' 'AllClasses.R' 'MIRit-package.R' 'RcppExports.R' 'association.R' 'batch-correction.R' 'data.R' 'differential-expression.R' 'enrichment.R' 'integration.R' 'show-methods.R' 'targets.R' 'topological-integration.R' 'utils.R' 'visualization.R' Suggests: BiocStyle, biomaRt, BSgenome.Hsapiens.UCSC.hg38, GenomicRanges, ggrepel, ggridges, Gviz, gwasrapidd, knitr, MonoPoly, org.Hs.eg.db, rmarkdown, testthat (>= 3.0.0) Depends: MultiAssayExperiment, R (>= 4.4.0) LazyData: false VignetteBuilder: knitr Config/testthat/edition: 3 LinkingTo: Rcpp Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev libglpk-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:02:17 UTC RemoteUrl: https://github.com/bioc/MIRit RemoteRef: HEAD RemoteSha: 116078895be27e9504c3381bb5705bbe1e52b580 NeedsCompilation: yes Packaged: 2026-07-04 00:54:34 UTC; root Author: Jacopo Ronchi [aut, cre] (ORCID: ), Maria Foti [fnd] (ORCID: ) Maintainer: Jacopo Ronchi