Package: Lheuristic Title: Detection of scatterplots with L-shaped pattern Version: 1.5.0 Authors@R: c( person("Sanchez Pla", "Alex", email ="asanchez@ub.edu", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-8673-7737")), person("Miro Cau", "Berta", email = "berta.miro@vhir.org", role = "aut", , comment = c(ORCID = "0000-0001-6049-8697"))) Description: The Lheuristic package identifies scatterpots that follow and L-shaped, negative distribution. It can be used to identify genes regulated by methylation by integration of an expression and a methylation array. The package uses two different methods to detect expression and methyaltion L- shapped scatterplots. The parameters can be changed to detect other scatterplot patterns. License: MIT + file LICENSE Depends: R (>= 4.4.0) biocViews: DNAMethylation, StatisticalMethod, MethylationArray Imports: Hmisc, stats, energy, grDevices, graphics, utils, MultiAssayExperiment, ggplot2, ggpubr Suggests: knitr, rmarkdown, testthat (>= 3.0.0) URL: https://github.com/ASPresearch/Lheuristic BugReports: https://github.com/ASPresearch/Lheuristic/issues VignetteBuilder: knitr Encoding: UTF-8 LazyData: false RoxygenNote: 7.3.2 Config/testthat/edition: 3 Config/pak/sysreqs: cmake make libgsl0-dev libicu-dev libuv1-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:04:47 UTC RemoteUrl: https://github.com/bioc/Lheuristic RemoteRef: HEAD RemoteSha: 6f0f0ae984928301c0f232e15067ffb91e6e281e NeedsCompilation: no Packaged: 2026-05-30 07:48:28 UTC; root Author: Sanchez Pla Alex [aut, cre] (ORCID: ), Miro Cau Berta [aut] (ORCID: ) Maintainer: Sanchez Pla Alex