Package: ILoReg Type: Package Title: ILoReg: a tool for high-resolution cell population identification from scRNA-Seq data Version: 1.23.0 Description: ILoReg is a tool for identification of cell populations from scRNA-seq data. In particular, ILoReg is useful for finding cell populations with subtle transcriptomic differences. The method utilizes a self-supervised learning method, called Iteratitive Clustering Projection (ICP), to find cluster probabilities, which are used in noise reduction prior to PCA and the subsequent hierarchical clustering and t-SNE steps. Additionally, functions for differential expression analysis to find gene markers for the populations and gene expression visualization are provided. Authors@R: c(person("Johannes", "Smolander", email = "johannes.smolander@gmail.com", role=c("cre", "aut")), person("Sini", "Junttila", role=c("aut")), person("Mikko S", "Venäläinen", role=c("aut")), person("Laura L", "Elo", role=c("aut"))) License: GPL-3 Imports: Matrix, parallel, foreach, aricode, LiblineaR, SparseM, ggplot2, cowplot, RSpectra, umap, Rtsne, fastcluster, parallelDist, cluster, dendextend, DescTools, plyr, scales, pheatmap, reshape2, dplyr, doRNG, SingleCellExperiment, SummarizedExperiment, S4Vectors, methods, stats, doSNOW, utils Depends: R (>= 4.0.0) Encoding: UTF-8 LazyData: TRUE RoxygenNote: 7.1.1 Suggests: knitr, rmarkdown, BiocStyle VignetteBuilder: knitr biocViews: SingleCell, Software, Clustering, DimensionReduction, RNASeq, Visualization, Transcriptomics, DataRepresentation, DifferentialExpression, Transcription, GeneExpression NeedsCompilation: no URL: https://github.com/elolab/ILoReg BugReports: https://github.com/elolab/ILoReg/issues Config/pak/sysreqs: cmake make libicu-dev libpng-dev libuv1-dev libssl-dev python3 libx11-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:53:15 UTC RemoteUrl: https://github.com/bioc/ILoReg RemoteRef: HEAD RemoteSha: 5f0e20dca622c5b9fbe39f5920703fb4fc7375ae Packaged: 2026-07-04 05:18:18 UTC; root Author: Johannes Smolander [cre, aut], Sini Junttila [aut], Mikko S Venäläinen [aut], Laura L Elo [aut] Maintainer: Johannes Smolander