Package: HumanRetinaLRSData Type: Package Title: Long-read RNA-seq gene count data from human retinal organoids Version: 1.1.0 Authors@R: c( person("Sowmya", "Parthiban", email = "sparthi1@jhu.edu", role = c("aut", "cre"))) Description: Dataset package containing gene and isoform count matrices, and sample metadata for long-read direct cDNA sequencing of human retinal organoids, 2D retinal ganglion cell (RGC) cultures, and flowthrough fractions from H9 and EP1 iPSC cell lines. Data were generated using Oxford Nanopore Technology (ONT) direct cDNA sequencing and mapped to the GRCh38 reference genome (GENCODE v46 annotation). The package provides accessor functions returning SummarizedExperiment objects for gene-level counts, isoform-level counts, and a matrix of allele-specific expression (ASE) gene counts. Data files are stored in flat CSV format in an Open Science Framework (OSF) repository and cached locally via BiocFileCache. License: MIT + file LICENSE Encoding: UTF-8 URL: https://github.com/sparthib/HumanRetinaLrsData BugReports: https://github.com/sparthib/HumanRetinaLrsData/issues biocViews: ExperimentData, RNASeqData, ExpressionData, Homo_sapiens_Data, CellCulture RoxygenNote: 7.3.2 Depends: R (>= 4.5.0), SummarizedExperiment Imports: osfr, BiocFileCache Suggests: testthat, knitr, rmarkdown, ggplot2, ggrepel VignetteBuilder: knitr Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:38:23 UTC RemoteUrl: https://github.com/bioc/HumanRetinaLRSData RemoteRef: HEAD RemoteSha: 85415f64fb013a1ce19ad4c2c8d9879886e8af1c NeedsCompilation: no Packaged: 2026-10-20 11:29:10 UTC; root Author: Sowmya Parthiban [aut, cre] Maintainer: Sowmya Parthiban