Package: HiSpaR Type: Package Title: Hierarchical Inference of Spatial Positions from Hi-C Data Version: 1.1.0 Date: 2026-01-15 Authors@R: c( person("Yingcheng", "Luo", email = "lyc22@mails.tsinghua.edu.cn", role = c("aut", "cre")) ) Description: Provides R bindings for HiSpa, a hierarchical Bayesian model for inferring three-dimensional chromatin structures from Hi-C contact matrices using Markov Chain Monte Carlo (MCMC) sampling. The package implements a cluster-based hierarchical approach that efficiently handles large-scale Hi-C datasets. It uses Rcpp and RcppArmadillo for efficient C++ integration with the original HiSpa C++ implementation, enabling fast computation of chromatin structure inference through parallel MCMC sampling. License: MIT + file LICENSE Depends: R (>= 4.5.0) Imports: Rcpp (>= 1.0.0), utils, stats, Matrix, HiCExperiment biocViews: Software, Epigenetics, HiC, StructuralPrediction, Bayesian, Spatial LinkingTo: Rcpp, RcppArmadillo SystemRequirements: C++17, GNU make, Armadillo (>= 9.0), OpenMP URL: https://github.com/masterStormtrooper/HiSpaR BugReports: https://github.com/masterStormtrooper/HiSpaR/issues Encoding: UTF-8 LazyData: false RoxygenNote: 7.3.3 Suggests: testthat (>= 3.0.0), knitr, rmarkdown, BiocStyle, rgl, HiContactsData, HiContacts, plotly, callr VignetteBuilder: knitr Config/pak/sysreqs: make libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:06:36 UTC RemoteUrl: https://github.com/bioc/HiSpaR RemoteRef: HEAD RemoteSha: 14a3af9fa4829689bde7578f18fe97212c71bce6 NeedsCompilation: yes Packaged: 2026-07-04 16:47:31 UTC; root Author: Yingcheng Luo [aut, cre] Maintainer: Yingcheng Luo