Package: HPiP Type: Package Title: Host-Pathogen Interaction Prediction Version: 1.19.0 Authors@R: c( person("Matineh", "Rahmatbakhsh", ,"matinerb.94@gmail.com",c("aut","trl","cre")), person("Mohan", "Babu", ,"mohan.babu@uregina.ca", c("led"))) Description: HPiP (Host-Pathogen Interaction Prediction) uses an ensemble learning algorithm for prediction of host-pathogen protein-protein interactions (HP-PPIs) using structural and physicochemical descriptors computed from amino acid-composition of host and pathogen proteins.The proposed package can effectively address data shortages and data unavailability for HP-PPI network reconstructions. Moreover, establishing computational frameworks in that regard will reveal mechanistic insights into infectious diseases and suggest potential HP-PPI targets, thus narrowing down the range of possible candidates for subsequent wet-lab experimental validations. Depends: R (>= 4.1) Imports: dplyr (>= 1.0.6), httr (>= 1.4.2), readr, tidyr, tibble, utils, stringr, magrittr, caret, corrplot, ggplot2, pROC, PRROC, igraph, graphics, stats, purrr, grDevices, protr, MCL License: MIT + file LICENSE Encoding: UTF-8 URL: https://github.com/mrbakhsh/HPiP BugReports: https://github.com/mrbakhsh/HPiP/issues VignetteBuilder: knitr Suggests: rmarkdown, colorspace, e1071, kernlab, ranger, SummarizedExperiment, Biostrings, randomForest, gprofiler2, gridExtra, ggthemes, BiocStyle, BiocGenerics, RUnit, tools, knitr biocViews: Proteomics, SystemsBiology, NetworkInference, StructuralPrediction, GenePrediction, Network RoxygenNote: 7.3.1 Config/pak/sysreqs: libglpk-dev libicu-dev libxml2-dev libssl-dev libx11-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:56:55 UTC RemoteUrl: https://github.com/bioc/HPiP RemoteRef: HEAD RemoteSha: a85ff66af9737a1c9aabcc9e2d3e40dc741697f9 NeedsCompilation: no Packaged: 2026-07-04 07:15:26 UTC; root Author: Matineh Rahmatbakhsh [aut, trl, cre], Mohan Babu [led] Maintainer: Matineh Rahmatbakhsh