Package: HDTD Type: Package Title: Statistical Inference about the Mean Matrix and the Covariance Matrices in High-Dimensional Transposable Data (HDTD) Version: 1.47.0 Authors@R: c( person(given = "Anestis", family = "Touloumis", email = "A.Touloumis@brighton.ac.uk", role = c("cre","aut"), comment = c(ORCID = "0000-0002-5965-1639")), person(given = "John C.", family = "Marioni", role = "aut", comment = c(ORCID = "0000-0001-9092-0852")), person(given = "Simon", family = "Tavar\\'{e}", role = "aut", comment = c(ORCID = "0000-0002-3716-4952")) ) Depends: R (>= 4.1) Suggests: knitr, rmarkdown Imports: stats, Rcpp (>= 1.0.1) LinkingTo: Rcpp, RcppArmadillo Description: Characterization of intra-individual variability using physiologically relevant measurements provides important insights into fundamental biological questions ranging from cell type identity to tumor development. For each individual, the data measurements can be written as a matrix with the different subsamples of the individual recorded in the columns and the different phenotypic units recorded in the rows. Datasets of this type are called high-dimensional transposable data. The HDTD package provides functions for conducting statistical inference for the mean relationship between the row and column variables and for the covariance structure within and between the row and column variables. License: GPL-3 biocViews: DifferentialExpression, Genetics, GeneExpression, Microarray, Sequencing, StatisticalMethod, Software VignetteBuilder: knitr URL: http://github.com/AnestisTouloumis/HDTD BugReports: http://github.com/AnestisTouloumis/HDTD/issues LazyData: false NeedsCompilation: yes RoxygenNote: 7.1.1 Encoding: UTF-8 Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:39:10 UTC RemoteUrl: https://github.com/bioc/HDTD RemoteRef: HEAD RemoteSha: fbbe8c060dcd201ec961df43b68f1ed3de9c9933 Packaged: 2026-07-04 23:12:47 UTC; root Author: Anestis Touloumis [cre, aut] (ORCID: ), John C. Marioni [aut] (ORCID: ), Simon Tavar\'{e} [aut] (ORCID: ) Maintainer: Anestis Touloumis