Package: GeoDiff Type: Package Title: Count model based differential expression and normalization on GeoMx RNA data Version: 1.19.0 Authors@R: c(person("Maddy", "Griswold", email = "mgriswold@nanostring.com", role = c("cre")), person("Lei", "Yang", email = "lyang@nanostring.com", role = c("aut")), person("Zhi", "Yang", email = "zyang@nanostring.com", role = c("aut"))) Description: A series of statistical models using count generating distributions for background modelling, feature and sample QC, normalization and differential expression analysis on GeoMx RNA data. The application of these methods are demonstrated by example data analysis vignette. Imports: Matrix, robust, plyr, lme4, Rcpp (>= 1.0.4.6), withr, methods, graphics, stats, testthat, GeomxTools, NanoStringNCTools LinkingTo: Rcpp, RcppArmadillo, roptim License: MIT + file LICENSE URL: https://github.com/Nanostring-Biostats/GeoDiff BugReports: https://github.com/Nanostring-Biostats/GeoDiff Encoding: UTF-8 Suggests: knitr, rmarkdown, dplyr VignetteBuilder: knitr Depends: R (>= 4.1.0), Biobase RoxygenNote: 7.1.2 biocViews: GeneExpression, DifferentialExpression, Normalization Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev make libicu-dev libpng-dev libuv1-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:57:23 UTC RemoteUrl: https://github.com/bioc/GeoDiff RemoteRef: HEAD RemoteSha: ea81008f7d7165412d0b5ca7384020d33dff7918 NeedsCompilation: yes Packaged: 2026-07-04 05:37:51 UTC; root Author: Maddy Griswold [cre], Lei Yang [aut], Zhi Yang [aut] Maintainer: Maddy Griswold