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{"Hugo_Symbol":"ACVR2A","Entrez_Gene_Id":92,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"2","Start_Position":148676122,"End_Position":148676122,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0EQ-01A-11W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0EQ-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"2c449ea9-c3ff-4726-8566-5933e2b7056d","Matched_Norm_Sample_UUID":"282ea476-ac8e-4aa3-ac9e-49fced7a4eb2","chromosome_name_WU":"2","start_WU":148676122,"stop_WU":148676122,"reference_WU":"C","variant_WU":"G","type_WU":"SNP","gene_name_WU":"ACVR2A","transcript_name_WU":"NM_001616.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.923","amino_acid_change_WU":"p.P308R","ucsc_cons_WU":"1.000","domain_WU":"HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase","all_domains_WU":"HMMPfam_Activin_recp,HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase,superfamily_Snake toxin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ADA","Entrez_Gene_Id":100,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"20","Start_Position":43257689,"End_Position":43257689,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CM-01A-31W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CM-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"fe8023d4-5476-4c58-bf70-cbf65cdd4327","Matched_Norm_Sample_UUID":"be44d49f-6519-4d7c-a1ba-577c7b365a37","chromosome_name_WU":"20","start_WU":43257689,"stop_WU":43257689,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"ADA","transcript_name_WU":"NM_000022.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.217","amino_acid_change_WU":"p.A73T","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_A_deaminase,superfamily_SSF51556","all_domains_WU":"HMMPfam_A_deaminase,PatternScan_A_DEAMINASE,superfamily_SSF51556","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ADAD1","Entrez_Gene_Id":132612,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"4","Start_Position":123304955,"End_Position":123304955,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"T","Tumor_Seq_Allele1":"T","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A04P-01A-31D-A128-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A04P-10A-01W-A055-09","Match_Norm_Seq_Allele1":"T","Match_Norm_Seq_Allele2":"T","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"a85cf239-ff51-46e7-9b88-4c2cb49c66b9","Matched_Norm_Sample_UUID":"aaef2ada-b81d-4e89-8add-a571603d67bb","chromosome_name_WU":"4","start_WU":123304955,"stop_WU":123304955,"reference_WU":"T","variant_WU":"G","type_WU":"SNP","gene_name_WU":"ADAD1","transcript_name_WU":"NM_139243.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"silent","c_position_WU":"c.363","amino_acid_change_WU":"p.G121","ucsc_cons_WU":"0.989","domain_WU":"HMMPfam_dsrm,HMMSmart_SM00358,superfamily_dsRNA-binding domain-like","all_domains_WU":"PatternScan_THIOL_PROTEASE_HIS,HMMPfam_dsrm,HMMSmart_SM00358,HMMPfam_A_deamin,HMMSmart_SM00552,superfamily_dsRNA-binding domain-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ADAM29","Entrez_Gene_Id":11086,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"4","Start_Position":175896776,"End_Position":175896776,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0EU-01A-22W-A071-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0EU-10A-01W-A071-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"de30da8f-903f-428e-a63d-59625fc858a9","Matched_Norm_Sample_UUID":"1583a7c5-c835-44fa-918a-1448abf6533d","chromosome_name_WU":"4","start_WU":175896776,"stop_WU":175896776,"reference_WU":"G","variant_WU":"T","type_WU":"SNP","gene_name_WU":"ADAM29","transcript_name_WU":"NM_001130703.1","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.100","amino_acid_change_WU":"p.V34L","ucsc_cons_WU":"0.994","domain_WU":"HMMPfam_Pep_M12B_propep","all_domains_WU":"HMMPfam_Reprolysin,HMMPfam_Disintegrin,HMMSmart_SM00050,superfamily_Blood coagulation inhibitor (disintegrin),HMMPfam_Pep_M12B_propep,HMMPfam_ADAM_CR,HMMSmart_SM00608,PatternScan_DISINTEGRIN_1,superfamily_Metalloproteases (zincins) catalytic domain","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ADAM33","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"20","Start_Position":3649953,"End_Position":3649953,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SN-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SN-10B-01D-A142-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"1b8d93f4-acc2-48ee-9ca8-a327eb0463c2","Matched_Norm_Sample_UUID":"14f376b8-4bd0-4931-9ddd-0b4b1cb89137","chromosome_name_WU":"20","start_WU":3649953,"stop_WU":3649953,"reference_WU":"G","variant_WU":"T","type_WU":"SNP","gene_name_WU":"ADAM33","transcript_name_WU":"NM_025220.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.2397","amino_acid_change_WU":"p.D799E","ucsc_cons_WU":"0.000","domain_WU":"NULL","all_domains_WU":"HMMPfam_Reprolysin,HMMPfam_Disintegrin,HMMSmart_SM00050,superfamily_Blood coagulation inhibitor (disintegrin),HMMPfam_Pep_M12B_propep,PatternScan_ZINC_PROTEASE,HMMPfam_ADAM_CR,HMMSmart_SM00608,PatternScan_EGF_2,HMMPfam_EGF_2,PatternScan_DISINTEGRIN_1,superfamily_Metalloproteases (zincins) catalytic domain","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ADAMDEC1","Entrez_Gene_Id":27299,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"8","Start_Position":24249788,"End_Position":24249788,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0EQ-01A-11W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0EQ-10A-01W-A055-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"2c449ea9-c3ff-4726-8566-5933e2b7056d","Matched_Norm_Sample_UUID":"282ea476-ac8e-4aa3-ac9e-49fced7a4eb2","chromosome_name_WU":"8","start_WU":24249788,"stop_WU":24249788,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"ADAMDEC1","transcript_name_WU":"NM_014479.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"silent","c_position_WU":"c.102","amino_acid_change_WU":"p.K34","ucsc_cons_WU":"0.000","domain_WU":"HMMPfam_Pep_M12B_propep","all_domains_WU":"HMMPfam_Reprolysin,HMMPfam_Disintegrin,HMMSmart_DISIN,PatternScan_CYSTEINE_SWITCH,HMMPfam_Pep_M12B_propep,PatternScan_ZINC_PROTEASE,PatternScan_DISINTEGRIN_1,superfamily_SSF55486","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ADAMTS15","Entrez_Gene_Id":170689,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"11","Start_Position":130318913,"End_Position":130318913,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0D3-01A-11D-A10Y-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0D3-10A-01D-A110-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"8183420e-7f44-4024-b3db-6b53ad293988","Matched_Norm_Sample_UUID":"e23f0ac2-c466-4431-a23a-94bf6a1f5db6","chromosome_name_WU":"11","start_WU":130318913,"stop_WU":130318913,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"ADAMTS15","transcript_name_WU":"NM_139055.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.45","amino_acid_change_WU":"p.T15","ucsc_cons_WU":"0.251","domain_WU":"HMMPfam_Pep_M12B_propep","all_domains_WU":"HMMPfam_TSP_1,HMMSmart_TSP1,superfamily_TSP1,HMMPfam_Reprolysin,PatternScan_CYSTEINE_SWITCH,HMMPfam_Pep_M12B_propep,PatternScan_ZINC_PROTEASE,HMMPfam_ADAM_spacer1,PatternScan_DISINTEGRIN_1,superfamily_SSF55486","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"ATP1B3","Entrez_Gene_Id":483,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"3","Start_Position":141622516,"End_Position":141622516,"Strand":"+","Variant_Classification":"Nonsense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CM-01A-31W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CM-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"fe8023d4-5476-4c58-bf70-cbf65cdd4327","Matched_Norm_Sample_UUID":"be44d49f-6519-4d7c-a1ba-577c7b365a37","chromosome_name_WU":"3","start_WU":141622516,"stop_WU":141622516,"reference_WU":"C","variant_WU":"G","type_WU":"SNP","gene_name_WU":"ATP1B3","transcript_name_WU":"NM_001679.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"nonsense","c_position_WU":"c.164","amino_acid_change_WU":"p.S55*","ucsc_cons_WU":"0.753","domain_WU":"HMMPfam_Na_K-ATPase","all_domains_WU":"HMMPfam_Na_K-ATPase,PatternScan_ATPASE_NA_K_BETA_1","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"ATP4A","Entrez_Gene_Id":495,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"19","Start_Position":36046578,"End_Position":36046578,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"T","Tumor_Seq_Allele1":"T","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0D0-01A-11W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0D0-10A-01W-A021-09","Match_Norm_Seq_Allele1":"T","Match_Norm_Seq_Allele2":"T","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"3f20d0fe-aaa1-40f1-b2c1-7f070f93aef5","Matched_Norm_Sample_UUID":"bbf1c43d-d7b3-4574-a074-d22ad537829c","chromosome_name_WU":"19","start_WU":36046578,"stop_WU":36046578,"reference_WU":"T","variant_WU":"G","type_WU":"SNP","gene_name_WU":"ATP4A","transcript_name_WU":"NM_000704.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.2006","amino_acid_change_WU":"p.K669T","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Hydrolase,superfamily_SSF56784,superfamily_SSF81665","all_domains_WU":"HMMPfam_Cation_ATPase_N,HMMPfam_Hydrolase,HMMPfam_Cation_ATPase_C,HMMPfam_E1-E2_ATPase,HMMPfam_H-K_ATPase_N,PatternScan_ATPASE_E1_E2,superfamily_SSF56784,superfamily_SSF81653,superfamily_SSF81660,superfamily_SSF81665","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ATP7B","Entrez_Gene_Id":540,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"13","Start_Position":52544779,"End_Position":52544779,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CX-01A-21W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CX-10A-01W-A021-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"975adb76-3561-41a0-959a-68da470816c7","Matched_Norm_Sample_UUID":"dd43a88d-fd04-4ce4-8bac-1478975304aa","chromosome_name_WU":"13","start_WU":52544779,"stop_WU":52544779,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"ATP7B","transcript_name_WU":"NM_000053.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.1392","amino_acid_change_WU":"p.G464","ucsc_cons_WU":"0.000","domain_WU":"NULL","all_domains_WU":"HMMPfam_Hydrolase,HMMPfam_HMA,superfamily_HMA heavy metal-associated domain,HMMPfam_E1-E2_ATPase,PatternScan_HMA_1,PatternScan_ATPASE_E1_E2,superfamily_HAD-like,superfamily_Calcium ATPase transduction domain A,superfamily_Metal cation-transporting ATPase ATP-binding domain N,superfamily_Calcium ATPase transmembrane domain M","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ATP8A2","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"13","Start_Position":26155956,"End_Position":26155956,"Strand":"+","Variant_Classification":"Splice_Site","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SI-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SI-10B-01D-A142-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"e218c272-a7e1-4bc9-b8c5-d2d1c903550f","Matched_Norm_Sample_UUID":"fbcab9dc-4a6b-4928-9459-699c9932e3e1","chromosome_name_WU":"13","start_WU":26155956,"stop_WU":26155956,"reference_WU":"G","variant_WU":"C","type_WU":"SNP","gene_name_WU":"ATP8A2","transcript_name_WU":"NM_016529.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"splice_site","c_position_WU":"c.2008-1","amino_acid_change_WU":"e23-1","ucsc_cons_WU":"1.000","domain_WU":"-","all_domains_WU":"-","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"ATPIF1","Entrez_Gene_Id":93974,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"1","Start_Position":28562879,"End_Position":28562915,"Strand":"+","Variant_Classification":"Frame_Shift_Del","Variant_Type":"DEL","Reference_Allele":"ATGTCGACCGGGGCGCGGGCTCCATCCGGGAAGCCGG","Tumor_Seq_Allele1":"ATGTCGACCGGGGCGCGGGCTCCATCCGGGAAGCCGG","Tumor_Seq_Allele2":"-","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SH-01A-11D-A099-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SH-10A-03D-A099-09","Match_Norm_Seq_Allele1":"ATGTCGACCGGGGCGCGGGCTCCATCCGGGAAGCCGG","Match_Norm_Seq_Allele2":"ATGTCGACCGGGGCGCGGGCTCCATCCGGGAAGCCGG","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"473d6ae4-162a-4136-b44f-fad42529a31a","Matched_Norm_Sample_UUID":"7df4bbf4-7ac5-4fd3-b0b9-ca6e49674cfd","chromosome_name_WU":"1","start_WU":28562879,"stop_WU":28562915,"reference_WU":"ATGTCGACCGGGGCGCGGGCTCCATCCGGGAAGCCGG","variant_WU":"-","type_WU":"DEL","gene_name_WU":"ATPIF1","transcript_name_WU":"NM_016311.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"frame_shift_del","c_position_WU":"c.95_131","amino_acid_change_WU":"p.N32fs","ucsc_cons_WU":"0.000:0.000:0.000:0.000:0.000:0.002:0.002:0.000:0.000:0.001:0.000:0.000:0.000:0.000:0.001:0.005:0.003:0.998:1.000:1.000:0.997:0.996:0.021:0.252:0.991:0.996:1.000:1.000:0.999:1.000:1.000:0.959:0.997:0.996:0.932:1.000:1.000","domain_WU":"HMMPfam_IATP","all_domains_WU":"HMMPfam_IATP","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"CDH16","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"16","Start_Position":66947420,"End_Position":66947420,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SI-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SI-10B-01D-A142-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"e218c272-a7e1-4bc9-b8c5-d2d1c903550f","Matched_Norm_Sample_UUID":"fbcab9dc-4a6b-4928-9459-699c9932e3e1","chromosome_name_WU":"16","start_WU":66947420,"stop_WU":66947420,"reference_WU":"C","variant_WU":"G","type_WU":"SNP","gene_name_WU":"CDH16","transcript_name_WU":"NM_004062.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.877","amino_acid_change_WU":"p.E293Q","ucsc_cons_WU":"0.886","domain_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like","all_domains_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"CDH2","Entrez_Gene_Id":1000,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"18","Start_Position":25565518,"End_Position":25565518,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CT-01A-31W-A071-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CT-10A-01W-A071-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"C","Tumor_Validation_Allele2":"G","Match_Norm_Validation_Allele1":"C","Match_Norm_Validation_Allele2":"C","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"2b412ad8-abda-4cf8-8f68-59dbce80031e","Matched_Norm_Sample_UUID":"b34c4ee7-2776-40c7-9b34-b53e5674aab8","chromosome_name_WU":"18","start_WU":25565518,"stop_WU":25565518,"reference_WU":"C","variant_WU":"G","type_WU":"SNP","gene_name_WU":"CDH2","transcript_name_WU":"NM_001792.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.1949","amino_acid_change_WU":"p.R650T","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like","all_domains_WU":"HMMPfam_Cadherin_C,HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_pro,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"CDH23","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"10","Start_Position":73563078,"End_Position":73563078,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SI-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SI-10B-01D-A142-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"e218c272-a7e1-4bc9-b8c5-d2d1c903550f","Matched_Norm_Sample_UUID":"fbcab9dc-4a6b-4928-9459-699c9932e3e1","chromosome_name_WU":"10","start_WU":73563078,"stop_WU":73563078,"reference_WU":"C","variant_WU":"G","type_WU":"SNP","gene_name_WU":"CDH23","transcript_name_WU":"NM_022124.5","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.7773","amino_acid_change_WU":"p.L2591","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like","all_domains_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"CDHR3","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"7","Start_Position":105636709,"End_Position":105636709,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SD-01A-11D-A10Y-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SD-10A-01D-A110-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"G","Tumor_Validation_Allele2":"A","Match_Norm_Validation_Allele1":"G","Match_Norm_Validation_Allele2":"G","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"1847727f-ea57-4e2e-84e5-a10e764c9096","Matched_Norm_Sample_UUID":"44ee7757-ca5e-4616-a3fc-5e30c8b6088c","chromosome_name_WU":"7","start_WU":105636709,"stop_WU":105636709,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"CDHR3","transcript_name_WU":"NM_152750.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.622","amino_acid_change_WU":"p.V208M","ucsc_cons_WU":"0.898","domain_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like","all_domains_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"CDHR5","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"11","Start_Position":621446,"End_Position":621446,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CX-01A-21W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CX-10A-01W-A021-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"975adb76-3561-41a0-959a-68da470816c7","Matched_Norm_Sample_UUID":"dd43a88d-fd04-4ce4-8bac-1478975304aa","chromosome_name_WU":"11","start_WU":621446,"stop_WU":621446,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"CDHR5","transcript_name_WU":"NM_021924.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.517","amino_acid_change_WU":"p.D173N","ucsc_cons_WU":"0.000","domain_WU":"HMMSmart_SM00112,superfamily_Cadherin-like","all_domains_WU":"HMMSmart_SM00112,PatternScan_CADHERIN_1,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"CDK12","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"17","Start_Position":37681111,"End_Position":37681111,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CW-01A-21D-A10Y-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CW-10A-01D-A110-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"da4f0f85-b16f-40fa-95c6-524d70d7ac4d","Matched_Norm_Sample_UUID":"b6b51168-dc64-4bb1-aca5-346a1f1c8b67","chromosome_name_WU":"17","start_WU":37681111,"stop_WU":37681111,"reference_WU":"G","variant_WU":"T","type_WU":"SNP","gene_name_WU":"CDK12","transcript_name_WU":"NM_016507.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.3280","amino_acid_change_WU":"p.V1094L","ucsc_cons_WU":"1.000","domain_WU":"NULL","all_domains_WU":"HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"CDKL1","Entrez_Gene_Id":8814,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"14","Start_Position":50824841,"End_Position":50824841,"Strand":"+","Variant_Classification":"Nonsense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A04P-01A-31D-A128-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A04P-10A-01W-A055-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"a85cf239-ff51-46e7-9b88-4c2cb49c66b9","Matched_Norm_Sample_UUID":"aaef2ada-b81d-4e89-8add-a571603d67bb","chromosome_name_WU":"14","start_WU":50824841,"stop_WU":50824841,"reference_WU":"G","variant_WU":"T","type_WU":"SNP","gene_name_WU":"CDKL1","transcript_name_WU":"ENST00000356146","transcript_species_WU":"human","transcript_source_WU":"ensembl","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"known","trv_type_WU":"nonsense","c_position_WU":"c.2127","amino_acid_change_WU":"p.C709*","ucsc_cons_WU":"0.000","domain_WU":"superfamily_Kinase_like","all_domains_WU":"PatternScan_PROTEIN_KINASE_ST,superfamily_Kinase_like,PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"CDKL2","Entrez_Gene_Id":8999,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"4","Start_Position":76529120,"End_Position":76529120,"Strand":"+","Variant_Classification":"Nonsense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CM-01A-31W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CM-10A-01W-A055-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"fe8023d4-5476-4c58-bf70-cbf65cdd4327","Matched_Norm_Sample_UUID":"be44d49f-6519-4d7c-a1ba-577c7b365a37","chromosome_name_WU":"4","start_WU":76529120,"stop_WU":76529120,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"CDKL2","transcript_name_WU":"NM_003948.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"nonsense","c_position_WU":"c.676","amino_acid_change_WU":"p.Q226*","ucsc_cons_WU":"1.000","domain_WU":"HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase","all_domains_WU":"HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"DIP2C","Entrez_Gene_Id":22982,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"10","Start_Position":323355,"End_Position":323355,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CQ-01A-21W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CQ-10A-01W-A055-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"fa0d7183-8757-4f95-87b2-2366a1dbd508","Matched_Norm_Sample_UUID":"a300b0ed-eb05-4a95-8947-258940ad090b","chromosome_name_WU":"10","start_WU":323355,"stop_WU":323355,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"DIP2C","transcript_name_WU":"NM_014974.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.4581","amino_acid_change_WU":"p.I1527","ucsc_cons_WU":"1.000","domain_WU":"superfamily_SSF56801","all_domains_WU":"HMMPfam_AMP-binding,HMMPfam_DMAP_binding,PatternScan_AMP_BINDING,superfamily_SSF56801","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"DLG1","Entrez_Gene_Id":1739,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"3","Start_Position":196846393,"End_Position":196846393,"Strand":"+","Variant_Classification":"Nonsense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CX-01A-21W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CX-10A-01W-A021-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"975adb76-3561-41a0-959a-68da470816c7","Matched_Norm_Sample_UUID":"dd43a88d-fd04-4ce4-8bac-1478975304aa","chromosome_name_WU":"3","start_WU":196846393,"stop_WU":196846393,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"DLG1","transcript_name_WU":"NM_004087.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"validated","trv_type_WU":"nonsense","c_position_WU":"c.1273","amino_acid_change_WU":"p.Q425*","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_PDZ_assoc","all_domains_WU":"HMMPfam_SH3_1,HMMSmart_SM00326,superfamily_SH3-domain,HMMPfam_PDZ,HMMSmart_SM00228,superfamily_PDZ domain-like,HMMSmart_SM00569,HMMPfam_Guanylate_kin,HMMSmart_SM00072,HMMPfam_L27_1,HMMPfam_PDZ_assoc,HMMPfam_Gua_kin_assoc_C,HMMPfam_MAGUK_N_PEST,PatternScan_GUANYLATE_KINASE_1,superfamily_L27 domain,superfamily_P-loop containing nucleoside triphosphate hydrolases","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"DLST","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"14","Start_Position":75355833,"End_Position":75355833,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SI-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SI-10B-01D-A142-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"e218c272-a7e1-4bc9-b8c5-d2d1c903550f","Matched_Norm_Sample_UUID":"fbcab9dc-4a6b-4928-9459-699c9932e3e1","chromosome_name_WU":"14","start_WU":75355833,"stop_WU":75355833,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"DLST","transcript_name_WU":"NM_001933.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.182","amino_acid_change_WU":"p.R61K","ucsc_cons_WU":"1.000","domain_WU":"NULL","all_domains_WU":"HMMPfam_Biotin_lipoyl,HMMPfam_2-oxoacid_dh,PatternScan_LIPOYL,superfamily_Single hybrid motif,superfamily_CoA-dependent acyltransferases","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"FARS2","Entrez_Gene_Id":10667,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"6","Start_Position":5431360,"End_Position":5431360,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A04P-01A-31D-A128-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A04P-10A-01W-A055-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"a85cf239-ff51-46e7-9b88-4c2cb49c66b9","Matched_Norm_Sample_UUID":"aaef2ada-b81d-4e89-8add-a571603d67bb","chromosome_name_WU":"6","start_WU":5431360,"stop_WU":5431360,"reference_WU":"G","variant_WU":"C","type_WU":"SNP","gene_name_WU":"FARS2","transcript_name_WU":"NM_006567.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.859","amino_acid_change_WU":"p.E287Q","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_tRNA-synt_2d,superfamily_SSF55681","all_domains_WU":"HMMPfam_tRNA-synt_2d,HMMPfam_FDX-ACB,superfamily_Fdx_AntiC_bd,superfamily_SSF55681","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"FASLG","Entrez_Gene_Id":356,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"1","Start_Position":172628648,"End_Position":172628648,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A04P-01A-31D-A128-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A04P-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"a85cf239-ff51-46e7-9b88-4c2cb49c66b9","Matched_Norm_Sample_UUID":"aaef2ada-b81d-4e89-8add-a571603d67bb","chromosome_name_WU":"1","start_WU":172628648,"stop_WU":172628648,"reference_WU":"C","variant_WU":"A","type_WU":"SNP","gene_name_WU":"FASLG","transcript_name_WU":"NM_000639.1","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.307","amino_acid_change_WU":"p.Q103K","ucsc_cons_WU":"1.000","domain_WU":"NULL","all_domains_WU":"HMMPfam_TNF,HMMSmart_SM00207,PatternScan_TNF_1,superfamily_TNF-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"FASN","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"17","Start_Position":80049393,"End_Position":80049393,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SI-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SI-10B-01D-A142-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"e218c272-a7e1-4bc9-b8c5-d2d1c903550f","Matched_Norm_Sample_UUID":"fbcab9dc-4a6b-4928-9459-699c9932e3e1","chromosome_name_WU":"17","start_WU":80049393,"stop_WU":80049393,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"FASN","transcript_name_WU":"NM_004104.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.1197","amino_acid_change_WU":"p.N399","ucsc_cons_WU":"0.228","domain_WU":"superfamily_Thiolase-like","all_domains_WU":"HMMPfam_Thioesterase,HMMPfam_adh_short,PatternScan_PHOSPHOPANTETHEINE,HMMPfam_PP-binding,superfamily_ACP-like,superfamily_GroES-like,HMMPfam_ADH_zinc_N,HMMPfam_Methyltransf_12,HMMPfam_ketoacyl-synt,HMMPfam_Ketoacyl-synt_C,HMMPfam_Acyl_transf_1,superfamily_FabD/lysophospholipase-like,superfamily_Probable ACP-binding domain of malonyl-CoA ACP transacylase,superfamily_Thiolase-like,superfamily_NAD(P)-binding Rossmann-fold domains,PatternScan_B_KETOACYL_SYNTHASE,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_alpha/beta-Hydrolases","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"FASTKD3","Entrez_Gene_Id":79072,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":7867557,"End_Position":7867557,"Strand":"+","Variant_Classification":"Nonsense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CX-01A-21W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CX-10A-01W-A021-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"975adb76-3561-41a0-959a-68da470816c7","Matched_Norm_Sample_UUID":"dd43a88d-fd04-4ce4-8bac-1478975304aa","chromosome_name_WU":"5","start_WU":7867557,"stop_WU":7867557,"reference_WU":"C","variant_WU":"A","type_WU":"SNP","gene_name_WU":"FASTKD3","transcript_name_WU":"NM_024091.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"validated","trv_type_WU":"nonsense","c_position_WU":"c.640","amino_acid_change_WU":"p.E214*","ucsc_cons_WU":"0.949","domain_WU":"NULL","all_domains_WU":"HMMPfam_FAST_1,HMMPfam_FAST_2,HMMPfam_RAP","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"FAT1","Entrez_Gene_Id":2195,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"4","Start_Position":187627851,"End_Position":187627851,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"T","Tumor_Seq_Allele1":"T","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0D0-01A-11W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0D0-10A-01W-A021-09","Match_Norm_Seq_Allele1":"T","Match_Norm_Seq_Allele2":"T","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"3f20d0fe-aaa1-40f1-b2c1-7f070f93aef5","Matched_Norm_Sample_UUID":"bbf1c43d-d7b3-4574-a074-d22ad537829c","chromosome_name_WU":"4","start_WU":187627851,"stop_WU":187627851,"reference_WU":"T","variant_WU":"C","type_WU":"SNP","gene_name_WU":"FAT1","transcript_name_WU":"NM_005245.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.3131","amino_acid_change_WU":"p.K1044R","ucsc_cons_WU":"0.954","domain_WU":"HMMPfam_Cadherin,superfamily_Concanavalin A-like lectins/glucanases,superfamily_Cadherin-like","all_domains_WU":"PatternScan_ASX_HYDROXYL,HMMSmart_SM00282,HMMSmart_SM00179,HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_EGF,HMMSmart_SM00181,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,superfamily_Cadherin-like,PatternScan_EGF_CA,superfamily_EGF/Laminin","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"FAT2","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":150922760,"End_Position":150922760,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"A","Tumor_Seq_Allele1":"A","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SG-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SG-10B-01D-A17G-09","Match_Norm_Seq_Allele1":"A","Match_Norm_Seq_Allele2":"A","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"39642c6d-9191-4746-8a9d-62d437bfdce8","Matched_Norm_Sample_UUID":"cd67f058-5ac6-427c-8b3d-d5732ca6683e","chromosome_name_WU":"5","start_WU":150922760,"stop_WU":150922760,"reference_WU":"A","variant_WU":"T","type_WU":"SNP","gene_name_WU":"FAT2","transcript_name_WU":"NM_001447.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.7928","amino_acid_change_WU":"p.V2643D","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Concanavalin A-like lectins/glucanases,superfamily_Cadherin-like","all_domains_WU":"HMMSmart_SM00282,HMMSmart_SM00179,HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_EGF,HMMSmart_SM00181,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,superfamily_Cadherin-like,superfamily_EGF/Laminin","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"FAT3","Entrez_Gene_Id":120114,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"11","Start_Position":92533189,"End_Position":92533189,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"T","Tumor_Seq_Allele1":"T","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SK-01A-12D-A099-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SK-10A-03D-A099-09","Match_Norm_Seq_Allele1":"T","Match_Norm_Seq_Allele2":"T","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"d1b43161-cbc1-4bf6-b8bb-a72a2e5e1150","Matched_Norm_Sample_UUID":"2a5384f3-fec7-4265-b104-987f0718574b","chromosome_name_WU":"11","start_WU":92533189,"stop_WU":92533189,"reference_WU":"T","variant_WU":"A","type_WU":"SNP","gene_name_WU":"FAT3","transcript_name_WU":"NM_001008781.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.7010","amino_acid_change_WU":"p.F2337Y","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Concanavalin A-like lectins/glucanases,superfamily_Cadherin-like","all_domains_WU":"PatternScan_ASX_HYDROXYL,HMMSmart_SM00282,HMMSmart_SM00179,HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_EGF,HMMSmart_SM00181,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,superfamily_Cadherin-like,PatternScan_EGF_CA,superfamily_EGF/Laminin","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"FAT4","Entrez_Gene_Id":79633,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"4","Start_Position":126238784,"End_Position":126238784,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0EQ-01A-11W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0EQ-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"2c449ea9-c3ff-4726-8566-5933e2b7056d","Matched_Norm_Sample_UUID":"282ea476-ac8e-4aa3-ac9e-49fced7a4eb2","chromosome_name_WU":"4","start_WU":126238784,"stop_WU":126238784,"reference_WU":"C","variant_WU":"G","type_WU":"SNP","gene_name_WU":"FAT4","transcript_name_WU":"NM_024582.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.1218","amino_acid_change_WU":"p.H406Q","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like","all_domains_WU":"PatternScan_ASX_HYDROXYL,HMMSmart_SM00282,HMMSmart_SM00179,HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_EGF,HMMSmart_SM00181,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_CA,superfamily_Cadherin-like,PatternScan_EGF_CA,superfamily_EGF/Laminin","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"HSD17B2","Entrez_Gene_Id":3294,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"16","Start_Position":82069075,"End_Position":82069075,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SO-01A-22D-A099-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SO-10A-03D-A099-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"C","Tumor_Validation_Allele2":"A","Match_Norm_Validation_Allele1":"C","Match_Norm_Validation_Allele2":"C","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"b3568259-c63c-4eb1-bbc7-af711ddd33db","Matched_Norm_Sample_UUID":"17ba8cdb-e35b-4496-a787-d1a7ee7d4a1e","chromosome_name_WU":"16","start_WU":82069075,"stop_WU":82069075,"reference_WU":"C","variant_WU":"A","type_WU":"SNP","gene_name_WU":"HSD17B2","transcript_name_WU":"NM_002153.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.46","amino_acid_change_WU":"p.P16T","ucsc_cons_WU":"0.001","domain_WU":"NULL","all_domains_WU":"HMMPfam_adh_short,PatternScan_ADH_SHORT,PatternScan_2FE2S_FER_1,superfamily_NAD(P)-binding Rossmann-fold domains","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"HSD17B4","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":118835164,"End_Position":118835164,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SG-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SG-10B-01D-A17G-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"39642c6d-9191-4746-8a9d-62d437bfdce8","Matched_Norm_Sample_UUID":"cd67f058-5ac6-427c-8b3d-d5732ca6683e","chromosome_name_WU":"5","start_WU":118835164,"stop_WU":118835164,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"HSD17B4","transcript_name_WU":"NM_000414.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.1125","amino_acid_change_WU":"p.P375","ucsc_cons_WU":"0.993","domain_WU":"superfamily_SSF54637","all_domains_WU":"HMMPfam_adh_short,PatternScan_ADH_SHORT,HMMPfam_MaoC_dehydratas,HMMPfam_SCP2,superfamily_NAD(P)-bd,superfamily_SCP2,superfamily_SSF54637","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"HSP90AB4P","Entrez_Gene_Id":664618,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"15","Start_Position":58983683,"End_Position":58983683,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"G","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0EM-01A-11W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0EM-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"C","Tumor_Validation_Allele2":"G","Match_Norm_Validation_Allele1":"C","Match_Norm_Validation_Allele2":"C","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"0e01c6b8-9edd-4965-b247-ee7e68124f48","Matched_Norm_Sample_UUID":"475ab163-650e-4139-b373-13cebd7a3f7d","chromosome_name_WU":"15","start_WU":58983683,"stop_WU":58983683,"reference_WU":"C","variant_WU":"G","type_WU":"SNP","gene_name_WU":"HSP90AB4P","transcript_name_WU":"ENST00000380522","transcript_species_WU":"human","transcript_source_WU":"ensembl","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"known","trv_type_WU":"missense","c_position_WU":"c.1137","amino_acid_change_WU":"p.E379D","ucsc_cons_WU":"1.000","domain_WU":"superfamily_Ribosomal_S5_D2-typ_fold,HMMPfam_HSP90","all_domains_WU":"HMMPfam_HATPase_c,HMMSmart_HATPase_c,superfamily_ATP_bd_ATPase,superfamily_Ribosomal_S5_D2-typ_fold,HMMPfam_HSP90,superfamily_SSF110942","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"HSP90B1","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"12","Start_Position":104337515,"End_Position":104337515,"Strand":"+","Variant_Classification":"Splice_Site","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SI-01A-11D-A142-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SI-10B-01D-A142-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"e218c272-a7e1-4bc9-b8c5-d2d1c903550f","Matched_Norm_Sample_UUID":"fbcab9dc-4a6b-4928-9459-699c9932e3e1","chromosome_name_WU":"12","start_WU":104337515,"stop_WU":104337515,"reference_WU":"G","variant_WU":"C","type_WU":"SNP","gene_name_WU":"HSP90B1","transcript_name_WU":"NM_003299.1","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"provisional","trv_type_WU":"splice_site","c_position_WU":"c.1891-1","amino_acid_change_WU":"e14-1","ucsc_cons_WU":"1.000","domain_WU":"-","all_domains_WU":"-","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"HSPA8","Entrez_Gene_Id":3312,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"11","Start_Position":122930605,"End_Position":122930605,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"A","Tumor_Seq_Allele1":"A","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0EV-01A-11W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0EV-10A-01W-A055-09","Match_Norm_Seq_Allele1":"A","Match_Norm_Seq_Allele2":"A","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"9433bf4f-23ba-4fe7-9503-1ad243d74225","Matched_Norm_Sample_UUID":"633b376d-d59f-4f31-8d1a-0b1d89650a8e","chromosome_name_WU":"11","start_WU":122930605,"stop_WU":122930605,"reference_WU":"A","variant_WU":"C","type_WU":"SNP","gene_name_WU":"HSPA8","transcript_name_WU":"NM_006597.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.696","amino_acid_change_WU":"p.D232E","ucsc_cons_WU":"0.997","domain_WU":"HMMPfam_HSP70,superfamily_Actin-like ATPase domain","all_domains_WU":"HMMPfam_HSP70,PatternScan_HSP70_1,PatternScan_HSP70_2,PatternScan_HSP70_3,superfamily_Heat shock protein 70kD (HSP70) peptide-binding domain,superfamily_Heat shock protein 70kD (HSP70) C-terminal subdomain,superfamily_Actin-like ATPase domain","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"HSPA9","Entrez_Gene_Id":3313,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":137909537,"End_Position":137909537,"Strand":"+","Variant_Classification":"Nonsense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CX-01A-21W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CX-10A-01W-A021-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"975adb76-3561-41a0-959a-68da470816c7","Matched_Norm_Sample_UUID":"dd43a88d-fd04-4ce4-8bac-1478975304aa","chromosome_name_WU":"5","start_WU":137909537,"stop_WU":137909537,"reference_WU":"G","variant_WU":"C","type_WU":"SNP","gene_name_WU":"HSPA9","transcript_name_WU":"NM_004134.6","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"nonsense","c_position_WU":"c.143","amino_acid_change_WU":"p.S48*","ucsc_cons_WU":"1.000","domain_WU":"NULL","all_domains_WU":"HMMPfam_HSP70,PatternScan_HSP70_1,PatternScan_HSP70_2,PatternScan_HSP70_3,superfamily_SSF100920,superfamily_SSF53067","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"HSPG2","Entrez_Gene_Id":3339,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"1","Start_Position":22211365,"End_Position":22211365,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CW-01A-21D-A10Y-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CW-10A-01D-A110-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"da4f0f85-b16f-40fa-95c6-524d70d7ac4d","Matched_Norm_Sample_UUID":"b6b51168-dc64-4bb1-aca5-346a1f1c8b67","chromosome_name_WU":"1","start_WU":22211365,"stop_WU":22211365,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"HSPG2","transcript_name_WU":"ENST00000374695","transcript_species_WU":"human","transcript_source_WU":"ensembl","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"known","trv_type_WU":"missense","c_position_WU":"c.1402","amino_acid_change_WU":"p.D468N","ucsc_cons_WU":"0.980","domain_WU":"HMMSmart_SM00406,HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_I-set,superfamily_Immunoglobulin","all_domains_WU":"HMMPfam_Laminin_B,HMMPfam_SEA,HMMSmart_SM00200,HMMSmart_SM00282,HMMSmart_SM00179,HMMPfam_Laminin_EGF,HMMSmart_SM00180,PatternScan_EGF_LAM_1,HMMPfam_Ldl_recept_a,HMMSmart_SM00192,PatternScan_LDLRA_1,superfamily_LDL receptor-like module,HMMSmart_SM00406,HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_EGF,HMMSmart_SM00181,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_G_1,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_I-set,HMMPfam_V-set,HMMPfam_ig,HMMSmart_SM00281,superfamily_Immunoglobulin,superfamily_EGF/Laminin","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"LAMP2","Entrez_Gene_Id":3920,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"X","Start_Position":119562414,"End_Position":119562414,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0D2-01A-21W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0D2-10A-01W-A055-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"05656575-69e7-4745-a89d-ca0568eb5559","Matched_Norm_Sample_UUID":"c830c663-95f6-40e0-9fd6-16586fa7d344","chromosome_name_WU":"X","start_WU":119562414,"stop_WU":119562414,"reference_WU":"G","variant_WU":"C","type_WU":"SNP","gene_name_WU":"LAMP2","transcript_name_WU":"NM_001122606.1","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.1161","amino_acid_change_WU":"p.G387","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Lamp","all_domains_WU":"HMMPfam_Lamp,PatternScan_LAMP_1","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"LAPTM5","Entrez_Gene_Id":7805,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"1","Start_Position":31206746,"End_Position":31206746,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"rs145384305","dbSNP_Val_Status":"byFrequency","Tumor_Sample_Barcode":"TCGA-A2-A0EO-01A-11W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0EO-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"8e2f9eb7-0660-47ae-b86e-652e99fa69ca","Matched_Norm_Sample_UUID":"daf64f76-2c6e-4d95-a8d9-1e4034f8d529","chromosome_name_WU":"1","start_WU":31206746,"stop_WU":31206746,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"LAPTM5","transcript_name_WU":"NM_006762.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.718","amino_acid_change_WU":"p.E240K","ucsc_cons_WU":"0.999","domain_WU":"HMMPfam_Mtp","all_domains_WU":"HMMPfam_Mtp","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"LARGE","Entrez_Gene_Id":9215,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"22","Start_Position":34157362,"End_Position":34157362,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SK-01A-12D-A099-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SK-10A-03D-A099-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"d1b43161-cbc1-4bf6-b8bb-a72a2e5e1150","Matched_Norm_Sample_UUID":"2a5384f3-fec7-4265-b104-987f0718574b","chromosome_name_WU":"22","start_WU":34157362,"stop_WU":34157362,"reference_WU":"G","variant_WU":"T","type_WU":"SNP","gene_name_WU":"LARGE","transcript_name_WU":"NM_004737.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.102","amino_acid_change_WU":"p.F34L","ucsc_cons_WU":"1.000","domain_WU":"NULL","all_domains_WU":"HMMPfam_Glyco_transf_8,superfamily_Nucleotide-diphospho-sugar transferases","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"LARP4B","Entrez_Gene_Id":23185,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"10","Start_Position":871788,"End_Position":871788,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CS-01A-11D-A10Y-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CS-10A-01D-A110-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"C","Tumor_Validation_Allele2":"A","Match_Norm_Validation_Allele1":"C","Match_Norm_Validation_Allele2":"C","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"fe96b832-cb86-4499-948a-5124a43d5c95","Matched_Norm_Sample_UUID":"748f5a6c-a00e-4da7-a556-d5460c51923d","chromosome_name_WU":"10","start_WU":871788,"stop_WU":871788,"reference_WU":"C","variant_WU":"A","type_WU":"SNP","gene_name_WU":"LARP4B","transcript_name_WU":"NM_015155.1","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"provisional","trv_type_WU":"missense","c_position_WU":"c.1148","amino_acid_change_WU":"p.G383V","ucsc_cons_WU":"1.000","domain_WU":"NULL","all_domains_WU":"HMMPfam_La,HMMSmart_SM00715,superfamily_Winged helix DNA-binding domain","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"LTBP2","Entrez_Gene_Id":4053,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"14","Start_Position":74972768,"End_Position":74972768,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CT-01A-31W-A071-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CT-10A-01W-A071-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"C","Tumor_Validation_Allele2":"T","Match_Norm_Validation_Allele1":"C","Match_Norm_Validation_Allele2":"C","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"2b412ad8-abda-4cf8-8f68-59dbce80031e","Matched_Norm_Sample_UUID":"b34c4ee7-2776-40c7-9b34-b53e5674aab8","chromosome_name_WU":"14","start_WU":74972768,"stop_WU":74972768,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"LTBP2","transcript_name_WU":"NM_000428.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.4160","amino_acid_change_WU":"p.R1387H","ucsc_cons_WU":"0.994","domain_WU":"HMMSmart_SM00179,HMMSmart_SM00181,superfamily_EGF/Laminin","all_domains_WU":"PatternScan_ASX_HYDROXYL,HMMSmart_SM00179,HMMPfam_TB,superfamily_TB module/8-cys domain,HMMPfam_EGF,HMMSmart_SM00181,superfamily_Growth factor receptor domain,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_CA,HMMPfam_EGF_2,PatternScan_EGF_CA,superfamily_EGF/Laminin","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"LYN","Entrez_Gene_Id":4067,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"8","Start_Position":56863331,"End_Position":56863331,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SO-01A-22D-A099-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SO-10A-03D-A099-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"G","Tumor_Validation_Allele2":"A","Match_Norm_Validation_Allele1":"G","Match_Norm_Validation_Allele2":"G","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"b3568259-c63c-4eb1-bbc7-af711ddd33db","Matched_Norm_Sample_UUID":"17ba8cdb-e35b-4496-a787-d1a7ee7d4a1e","chromosome_name_WU":"8","start_WU":56863331,"stop_WU":56863331,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"LYN","transcript_name_WU":"NM_002350.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.475","amino_acid_change_WU":"p.E159K","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_SH2,HMMSmart_SM00252,superfamily_SH2 domain","all_domains_WU":"HMMPfam_SH2,HMMSmart_SM00252,HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,HMMPfam_SH3_1,HMMSmart_SM00326,superfamily_SH3-domain,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_TYR,superfamily_Protein kinase-like (PK-like),PatternScan_PROTEIN_KINASE_ATP,superfamily_SH2 domain","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"LYSMD3","Entrez_Gene_Id":116068,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":89815236,"End_Position":89815236,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SO-01A-22D-A099-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SO-10A-03D-A099-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"G","Tumor_Validation_Allele2":"C","Match_Norm_Validation_Allele1":"G","Match_Norm_Validation_Allele2":"G","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"b3568259-c63c-4eb1-bbc7-af711ddd33db","Matched_Norm_Sample_UUID":"17ba8cdb-e35b-4496-a787-d1a7ee7d4a1e","chromosome_name_WU":"5","start_WU":89815236,"stop_WU":89815236,"reference_WU":"G","variant_WU":"C","type_WU":"SNP","gene_name_WU":"LYSMD3","transcript_name_WU":"NM_198273.1","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.321","amino_acid_change_WU":"p.I107M","ucsc_cons_WU":"1.000","domain_WU":"HMMSmart_SM00257","all_domains_WU":"HMMSmart_SM00257,HMMPfam_LysM","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"LYST","Entrez_Gene_Id":1130,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"1","Start_Position":235969153,"End_Position":235969153,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CT-01A-31W-A071-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CT-10A-01W-A071-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"C","Tumor_Validation_Allele2":"T","Match_Norm_Validation_Allele1":"C","Match_Norm_Validation_Allele2":"C","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"2b412ad8-abda-4cf8-8f68-59dbce80031e","Matched_Norm_Sample_UUID":"b34c4ee7-2776-40c7-9b34-b53e5674aab8","chromosome_name_WU":"1","start_WU":235969153,"stop_WU":235969153,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"LYST","transcript_name_WU":"NM_000081.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.3283","amino_acid_change_WU":"p.E1095K","ucsc_cons_WU":"0.998","domain_WU":"NULL","all_domains_WU":"HMMPfam_Beach,superfamily_BEACH domain,PatternScan_COPPER_BLUE,HMMSmart_SM00320,superfamily_WD40 repeat-like,PatternScan_WD_REPEATS_1,HMMPfam_WD40,superfamily_PH domain-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"MAB21L1","Entrez_Gene_Id":4081,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"13","Start_Position":36050009,"End_Position":36050009,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A04P-01A-31D-A128-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A04P-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"a85cf239-ff51-46e7-9b88-4c2cb49c66b9","Matched_Norm_Sample_UUID":"aaef2ada-b81d-4e89-8add-a571603d67bb","chromosome_name_WU":"13","start_WU":36050009,"stop_WU":36050009,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"MAB21L1","transcript_name_WU":"NM_005584.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.267","amino_acid_change_WU":"p.V89","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Mab-21","all_domains_WU":"HMMPfam_Mab-21","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"MACF1","Entrez_Gene_Id":23499,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"1","Start_Position":39753221,"End_Position":39753222,"Strand":"+","Variant_Classification":"Frame_Shift_Del","Variant_Type":"DEL","Reference_Allele":"TA","Tumor_Seq_Allele1":"TA","Tumor_Seq_Allele2":"-","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SO-01A-22D-A099-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SO-10A-03D-A099-09","Match_Norm_Seq_Allele1":"TA","Match_Norm_Seq_Allele2":"TA","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"b3568259-c63c-4eb1-bbc7-af711ddd33db","Matched_Norm_Sample_UUID":"17ba8cdb-e35b-4496-a787-d1a7ee7d4a1e","chromosome_name_WU":"1","start_WU":39753221,"stop_WU":39753222,"reference_WU":"TA","variant_WU":"-","type_WU":"DEL","gene_name_WU":"MACF1","transcript_name_WU":"NM_012090.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"frame_shift_del","c_position_WU":"c.1787_1788","amino_acid_change_WU":"p.V596fs","ucsc_cons_WU":"1.000:0.998","domain_WU":"HMMSmart_SM00150,superfamily_Spectrin repeat","all_domains_WU":"PatternScan_ACTININ_1,PatternScan_ACTININ_2,HMMPfam_CH,HMMSmart_SM00033,HMMPfam_Spectrin,HMMSmart_SM00054,HMMPfam_GAS2,HMMSmart_SM00243,superfamily_Calponin-homology domain CH-domain,PatternScan_GLYCOSYL_HYDROL_F5,HMMSmart_SM00150,PatternScan_EF_HAND_1,HMMPfam_efhand,superfamily_Spectrin repeat,superfamily_EF-hand","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"MORC1","Entrez_Gene_Id":27136,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"3","Start_Position":108812333,"End_Position":108812333,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A1-A0SO-01A-22D-A099-09","Matched_Norm_Sample_Barcode":"TCGA-A1-A0SO-10A-03D-A099-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"C","Tumor_Validation_Allele2":"A","Match_Norm_Validation_Allele1":"C","Match_Norm_Validation_Allele2":"C","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"b3568259-c63c-4eb1-bbc7-af711ddd33db","Matched_Norm_Sample_UUID":"17ba8cdb-e35b-4496-a787-d1a7ee7d4a1e","chromosome_name_WU":"3","start_WU":108812333,"stop_WU":108812333,"reference_WU":"C","variant_WU":"A","type_WU":"SNP","gene_name_WU":"MORC1","transcript_name_WU":"NM_014429.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.639","amino_acid_change_WU":"p.L213F","ucsc_cons_WU":"1.000","domain_WU":"superfamily_ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase","all_domains_WU":"HMMPfam_HATPase_c,superfamily_ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase,HMMPfam_zf-CW","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"MRPS7","Entrez_Gene_Id":51081,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"17","Start_Position":73261941,"End_Position":73261941,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0D0-01A-11W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0D0-10A-01W-A021-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"3f20d0fe-aaa1-40f1-b2c1-7f070f93aef5","Matched_Norm_Sample_UUID":"bbf1c43d-d7b3-4574-a074-d22ad537829c","chromosome_name_WU":"17","start_WU":73261941,"stop_WU":73261941,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"MRPS7","transcript_name_WU":"NM_015971.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.666","amino_acid_change_WU":"p.R222","ucsc_cons_WU":"0.899","domain_WU":"HMMPfam_Ribosomal_S7,superfamily_Ribosomal protein S7","all_domains_WU":"HMMPfam_Ribosomal_S7,superfamily_Ribosomal protein S7","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"MST1P9","Entrez_Gene_Id":0,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"1","Start_Position":17083652,"End_Position":17083652,"Strand":"+","Variant_Classification":"RNA","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"rs113710576","dbSNP_Val_Status":"byCluster","Tumor_Sample_Barcode":"TCGA-A2-A0CU-01A-12W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CU-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"a9aa68af-f5fe-4ac0-987f-8af49b85c231","Matched_Norm_Sample_UUID":"f41d6d14-ad4f-49d5-a4fb-6bdd1b6dbddc","chromosome_name_WU":"1","start_WU":17083652,"stop_WU":17083652,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"MST1P9","transcript_name_WU":"NR_002729.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"validated","trv_type_WU":"rna","c_position_WU":"NULL","amino_acid_change_WU":"NULL","ucsc_cons_WU":"0.765","domain_WU":"-","all_domains_WU":"-","deletion_substructures_WU":"-","transcript_error":"pseudogene"}
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{"Hugo_Symbol":"MYH11","Entrez_Gene_Id":4629,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"16","Start_Position":15818522,"End_Position":15818522,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CT-01A-31W-A071-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CT-10A-01W-A071-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"G","Tumor_Validation_Allele2":"C","Match_Norm_Validation_Allele1":"G","Match_Norm_Validation_Allele2":"G","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"2b412ad8-abda-4cf8-8f68-59dbce80031e","Matched_Norm_Sample_UUID":"b34c4ee7-2776-40c7-9b34-b53e5674aab8","chromosome_name_WU":"16","start_WU":15818522,"stop_WU":15818522,"reference_WU":"G","variant_WU":"C","type_WU":"SNP","gene_name_WU":"MYH11","transcript_name_WU":"NM_001040114.1","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.4119","amino_acid_change_WU":"p.I1373M","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Myosin_tail_1","all_domains_WU":"HMMPfam_IQ,HMMSmart_IQ,HMMPfam_Myosin_head,HMMSmart_MYSc,HMMPfam_Myosin_tail_1,HMMPfam_Myosin_N,superfamily_SSF52540","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"PBRM1","Entrez_Gene_Id":55193,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"3","Start_Position":52651338,"End_Position":52651338,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0D2-01A-21W-A050-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0D2-10A-01W-A055-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"05656575-69e7-4745-a89d-ca0568eb5559","Matched_Norm_Sample_UUID":"c830c663-95f6-40e0-9fd6-16586fa7d344","chromosome_name_WU":"3","start_WU":52651338,"stop_WU":52651338,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"PBRM1","transcript_name_WU":"NM_018165.4","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":-1,"transcript_status_WU":"validated","trv_type_WU":"missense","c_position_WU":"c.1662","amino_acid_change_WU":"p.M554I","ucsc_cons_WU":"1.000","domain_WU":"HMMPfam_Bromodomain,HMMSmart_BROMO,superfamily_Bromodomain,PatternScan_BROMODOMAIN_1","all_domains_WU":"HMMPfam_HMG_box,HMMSmart_HMG,HMMPfam_BAH,HMMSmart_BAH,HMMPfam_Bromodomain,HMMSmart_BROMO,superfamily_Bromodomain,superfamily_HMG-box,PatternScan_BROMODOMAIN_1","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"PCDHA12","Entrez_Gene_Id":56137,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":140256806,"End_Position":140256806,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CV-01A-31D-A10Y-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CV-10A-01D-A110-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"5d1dead5-d9a5-42d3-a703-4c38ad6e8f57","Matched_Norm_Sample_UUID":"7d4e8176-424e-41d9-ba1c-48feff2d2350","chromosome_name_WU":"5","start_WU":140256806,"stop_WU":140256806,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"PCDHA12","transcript_name_WU":"NM_018903.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.1749","amino_acid_change_WU":"p.R583","ucsc_cons_WU":"0.000","domain_WU":"superfamily_Cadherin-like","all_domains_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"PCDHA13","Entrez_Gene_Id":56136,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":140263402,"End_Position":140263402,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A04P-01A-31D-A128-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A04P-10A-01W-A055-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"a85cf239-ff51-46e7-9b88-4c2cb49c66b9","Matched_Norm_Sample_UUID":"aaef2ada-b81d-4e89-8add-a571603d67bb","chromosome_name_WU":"5","start_WU":140263402,"stop_WU":140263402,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"PCDHA13","transcript_name_WU":"NM_018904.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.1549","amino_acid_change_WU":"p.V517M","ucsc_cons_WU":"0.783","domain_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like","all_domains_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
{"Hugo_Symbol":"PCDHA4","Entrez_Gene_Id":56144,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":140188814,"End_Position":140188814,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"A","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CT-01A-31W-A071-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CT-10A-01W-A071-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"G","Tumor_Validation_Allele2":"A","Match_Norm_Validation_Allele1":"G","Match_Norm_Validation_Allele2":"G","Verification_Status":"Unknown","Validation_Status":"Valid","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"Illumina_WXS_gDNA","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"2b412ad8-abda-4cf8-8f68-59dbce80031e","Matched_Norm_Sample_UUID":"b34c4ee7-2776-40c7-9b34-b53e5674aab8","chromosome_name_WU":"5","start_WU":140188814,"stop_WU":140188814,"reference_WU":"G","variant_WU":"A","type_WU":"SNP","gene_name_WU":"PCDHA4","transcript_name_WU":"NM_018907.2","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.2042","amino_acid_change_WU":"p.R681Q","ucsc_cons_WU":"0.016","domain_WU":"NULL","all_domains_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"PCDHAC1","Entrez_Gene_Id":56135,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"5","Start_Position":140306796,"End_Position":140306796,"Strand":"+","Variant_Classification":"Silent","Variant_Type":"SNP","Reference_Allele":"C","Tumor_Seq_Allele1":"C","Tumor_Seq_Allele2":"T","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A0CX-01A-21W-A019-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A0CX-10A-01W-A021-09","Match_Norm_Seq_Allele1":"C","Match_Norm_Seq_Allele2":"C","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"975adb76-3561-41a0-959a-68da470816c7","Matched_Norm_Sample_UUID":"dd43a88d-fd04-4ce4-8bac-1478975304aa","chromosome_name_WU":"5","start_WU":140306796,"stop_WU":140306796,"reference_WU":"C","variant_WU":"T","type_WU":"SNP","gene_name_WU":"PCDHAC1","transcript_name_WU":"NM_018898.3","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"silent","c_position_WU":"c.319","amino_acid_change_WU":"p.L107","ucsc_cons_WU":"1.000","domain_WU":"HMMSmart_SM00112,superfamily_Cadherin-like","all_domains_WU":"HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin-like","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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{"Hugo_Symbol":"PTPRO","Entrez_Gene_Id":5800,"Center":"genome.wustl.edu","NCBI_Build":37,"Chromosome":"12","Start_Position":15637127,"End_Position":15637127,"Strand":"+","Variant_Classification":"Missense_Mutation","Variant_Type":"SNP","Reference_Allele":"G","Tumor_Seq_Allele1":"G","Tumor_Seq_Allele2":"C","dbSNP_RS":"novel","dbSNP_Val_Status":"","Tumor_Sample_Barcode":"TCGA-A2-A04P-01A-31D-A128-09","Matched_Norm_Sample_Barcode":"TCGA-A2-A04P-10A-01W-A055-09","Match_Norm_Seq_Allele1":"G","Match_Norm_Seq_Allele2":"G","Tumor_Validation_Allele1":"","Tumor_Validation_Allele2":"","Match_Norm_Validation_Allele1":"","Match_Norm_Validation_Allele2":"","Verification_Status":"Unknown","Validation_Status":"Untested","Mutation_Status":"Somatic","Sequencing_Phase":"Phase_IV","Sequence_Source":"WXS","Validation_Method":"none","Score":1,"BAM_File":"dbGAP","Sequencer":"Illumina GAIIx","Tumor_Sample_UUID":"a85cf239-ff51-46e7-9b88-4c2cb49c66b9","Matched_Norm_Sample_UUID":"aaef2ada-b81d-4e89-8add-a571603d67bb","chromosome_name_WU":"12","start_WU":15637127,"stop_WU":15637127,"reference_WU":"G","variant_WU":"C","type_WU":"SNP","gene_name_WU":"PTPRO","transcript_name_WU":"NM_030667.1","transcript_species_WU":"human","transcript_source_WU":"genbank","transcript_version_WU":"58_37c","strand_WU":1,"transcript_status_WU":"reviewed","trv_type_WU":"missense","c_position_WU":"c.295","amino_acid_change_WU":"p.V99L","ucsc_cons_WU":"1.000","domain_WU":"superfamily_Fibronectin type III","all_domains_WU":"HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMSmart_SM00404,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II","deletion_substructures_WU":"-","transcript_error":"no_errors"}
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