{"Genesets":"GO:0002503","Term":"peptide antigen assembly with MHC class II protein complex","Annotated":13,"Significant":13,"Expected":0.72,"Rank in p.value_classic":33,"p.value_elim":3.7e-17,"p.value_classic":4e-17,"Genes":"B2M,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5"} {"Genesets":"GO:0045087","Term":"innate immune response","Annotated":620,"Significant":119,"Expected":34.23,"Rank in p.value_classic":9,"p.value_elim":1.1e-13,"Genes":"ACOD1,ADAM8,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CX3CR1,CXCL10,CYLD,DDX60,DTX3L,EDN1,FCN1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GSDMD,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-E,HLA-F,HLA-G,IFI27,IFI35,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL27,IRF1,IRF7,ISG20,JAK2,JAK3,KLRK1,LAG3,LILRA2,LYN,MCOLN2,MEFV,MSRB1,NCF1,NLRC5,NMI,NOD2,NUB1,OAS2,OPTN,PARP14,PML,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RSAD2,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SOCS1,STAT1,STAT2,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TRAFD1,TRIM17,TRIM22,TRIM31,UBD,ZBP1,ZNFX1"} {"Genesets":"GO:0019886","Term":"antigen processing and presentation of exogenous peptide antigen via MHC class II","Annotated":26,"Significant":15,"Expected":1.44,"Rank in p.value_classic":60,"p.value_elim":4.7e-13,"p.value_classic":5.1e-13,"Genes":"B2M,CD74,CTSS,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5"} {"Genesets":"GO:0002250","Term":"adaptive immune response","Annotated":350,"Significant":92,"Expected":19.32,"Rank in p.value_classic":6,"p.value_elim":1.6e-12,"Genes":"B2M,BCL6,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD1A,CD1C,CD274,CD28,CD40,CD7,CD74,CD80,CEACAM1,CLEC10A,CLEC6A,CR1L,CSF2RB,CTLA4,CTSS,CX3CR1,ERAP2,EXO1,FGL1,GPR183,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL18BP,IL27,IL4I1,IRF1,IRF7,ITK,JAK2,JAK3,KLRK1,LAG3,LAMP3,LILRA1,LILRB3,LYN,MCOLN2,NOD2,P2RX7,PDCD1,PDCD1LG2,RELB,RIPK2,RNF19B,RSAD2,SERPING1,SIT1,SLAMF1,SLAMF6,SLAMF7,SLC11A1,TAP1,TAP2,TBX21,TLR8,TNFRSF11A,TNFRSF21,TNFSF13B,TNFSF18,ZC3H12A"} {"Genesets":"GO:0001916","Term":"positive regulation of T cell mediated cytotoxicity","Annotated":25,"Significant":14,"Expected":1.38,"Rank in p.value_classic":70,"p.value_elim":5.1e-12,"p.value_classic":5.5e-12,"Genes":"B2M,CD1A,CD1C,HLA-A,HLA-B,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,P2RX7,TAP2"} {"Genesets":"GO:0019885","Term":"antigen processing and presentation of endogenous peptide antigen via MHC class I","Annotated":15,"Significant":11,"Expected":0.83,"Rank in p.value_classic":89,"p.value_elim":1.4e-11,"p.value_classic":1.5e-11,"Genes":"B2M,ERAP2,HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G,TAP1,TAP2,TAPBP"} {"Genesets":"GO:0034341","Term":"response to interferon-gamma","Annotated":119,"Significant":37,"Expected":6.57,"Rank in p.value_classic":24,"p.value_elim":1.7e-11,"p.value_classic":1.3e-18,"Genes":"ACOD1,CALCOCO2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,CIITA,EDN1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,HLA-DPA1,IFITM1,IFITM2,IFITM3,IL12RB1,IRF1,JAK2,MEFV,NLRC5,NMI,NUB1,PARP14,RAB20,SLC11A1,SOCS1,STAT1,UBD"} {"Genesets":"GO:0051607","Term":"defense response to virus","Annotated":259,"Significant":45,"Expected":14.3,"Rank in p.value_classic":68,"p.value_elim":8.2e-10,"p.value_classic":5e-12,"Genes":"ACOD1,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,CD40,CXCL10,CXCL9,DDX60,DTX3L,FGL2,GBP1,GBP3,GBP7,IFI27,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12RB1,IL15,IL27,IRF1,IRF7,ISG20,NLRC5,OAS2,PMAIP1,PML,RSAD2,RTP4,SERINC5,STAT1,STAT2,TLR7,TLR8,TRIM22,TSPAN32,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0002381","Term":"immunoglobulin production involved in immunoglobulin-mediated immune response","Annotated":64,"Significant":18,"Expected":3.53,"Rank in p.value_classic":133,"p.value_elim":5.5e-09,"p.value_classic":6e-09,"Genes":"B2M,BCL6,CD28,CD40,EXO1,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,TBX21"} {"Genesets":"GO:0032729","Term":"positive regulation of interferon-gamma production","Annotated":65,"Significant":18,"Expected":3.59,"Rank in p.value_classic":136,"p.value_elim":7.2e-09,"p.value_classic":7.9e-09,"Genes":"BTN3A1,BTN3A2,HLA-A,HLA-DPA1,HLA-DPB1,IL12A,IL12RB1,IL12RB2,IL27,JAK2,KLRK1,PDE4B,RIPK2,SLAMF1,SLAMF6,SLC11A1,TLR7,TLR8"} {"Genesets":"GO:0006958","Term":"complement activation, classical pathway","Annotated":21,"Significant":10,"Expected":1.16,"Rank in p.value_classic":158,"p.value_elim":4.8e-08,"p.value_classic":5e-08,"Genes":"C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CR1L,SERPING1"} {"Genesets":"GO:0006954","Term":"inflammatory response","Annotated":638,"Significant":86,"Expected":35.22,"Rank in p.value_classic":43,"p.value_elim":7.8e-08,"p.value_classic":5.5e-15,"Genes":"ACOD1,ADAM8,ADGRE5,ADORA3,AGT,AIM2,AOC3,APOL2,APOL3,APPL2,BCL6,C3,C4A,C4B,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD28,CD40,CDH5,CIITA,CRHBP,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,GBP5,GGT5,GHRL,GPR31,GSDMD,HGF,HLA-DRB1,HLA-E,IDO1,IFI35,IL15,IL1RN,IL22RA2,IL27,IL31RA,JAK2,KARS1,KLF4,LRRK2,LY75,LYN,MEFV,MMP25,MMP9,NCF1,NLRP12,NMI,NOD2,OSM,P2RX7,POLB,PTGER4,RELB,RIPK2,SBNO2,SLAMF1,SLAMF8,SLC11A1,STAP1,SUCNR1,TICAM2,TLR10,TLR5,TLR7,TLR8,TNFAIP6,TNFRSF11A,TNFSF18,VCAM1,ZBP1,ZC3H12A"} {"Genesets":"GO:0071346","Term":"cellular response to interferon-gamma","Annotated":100,"Significant":25,"Expected":5.52,"Rank in p.value_classic":101,"p.value_elim":1.7e-07,"p.value_classic":1.1e-10,"Genes":"ACOD1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,EDN1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,HLA-DPA1,IL12RB1,IRF1,JAK2,NLRC5,NMI,PARP14,RAB20,SOCS1,STAT1"} {"Genesets":"GO:0070098","Term":"chemokine-mediated signaling pathway","Annotated":65,"Significant":16,"Expected":3.59,"Rank in p.value_classic":177,"p.value_elim":3e-07,"p.value_classic":3.2e-07,"Genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,EDN1,LYN,PADI2"} {"Genesets":"GO:0000727","Term":"double-strand break repair via break-induced replication","Annotated":11,"Significant":7,"Expected":0.61,"Rank in p.value_classic":184,"p.value_elim":4e-07,"p.value_classic":4.1e-07,"Genes":"CDC45,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7"} {"Genesets":"GO:0050830","Term":"defense response to Gram-positive bacterium","Annotated":60,"Significant":15,"Expected":3.31,"Rank in p.value_classic":192,"p.value_elim":5.6e-07,"p.value_classic":6.1e-07,"Genes":"CASP4,GBP2,GBP4,GBP6,GBP7,GSDMD,H2BC21,HLA-A,HLA-E,IL12A,KLRK1,NOD2,P2RX7,RIPK2,TNFSF8"} {"Genesets":"GO:0045071","Term":"negative regulation of viral genome replication","Annotated":53,"Significant":14,"Expected":2.93,"Rank in p.value_classic":195,"p.value_elim":6.5e-07,"p.value_classic":6.9e-07,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,OAS2,PARP10,RSAD2,ZNFX1"} {"Genesets":"GO:0071356","Term":"cellular response to tumor necrosis factor","Annotated":194,"Significant":29,"Expected":10.71,"Rank in p.value_classic":207,"p.value_elim":8e-07,"p.value_classic":8.9e-07,"Genes":"ACOD1,AIM2,BRCA1,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CRHBP,CYLD,EDN1,FAS,GBP1,GBP2,GBP3,IL18BP,JAK2,PID1,STAT1,TNFRSF11A,TNFRSF21,TNFSF13B,TNFSF18,VCAM1,ZC3H12A"} {"Genesets":"GO:0070234","Term":"positive regulation of T cell apoptotic process","Annotated":12,"Significant":7,"Expected":0.66,"Rank in p.value_classic":209,"p.value_elim":9.1e-07,"p.value_classic":9.4e-07,"Genes":"ADAM8,BCL2L11,CCL5,CD274,IDO1,P2RX7,PDCD1"} {"Genesets":"GO:0002475","Term":"antigen processing and presentation via MHC class Ib","Annotated":12,"Significant":7,"Expected":0.66,"Rank in p.value_classic":210,"p.value_elim":9.1e-07,"p.value_classic":9.4e-07,"Genes":"B2M,CD1A,CD1C,HLA-E,HLA-F,HLA-G,TAP2"} {"Genesets":"GO:0006955","Term":"immune response","Annotated":1247,"Significant":216,"Expected":68.85,"Rank in p.value_classic":1,"p.value_elim":3.3e-06,"Genes":"ACOD1,ADAM8,ADGRE5,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,B2M,BANK1,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CR1L,CSF2RB,CTLA4,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,CYSLTR2,DDX60,DLL1,DTX3L,DYSF,EDA,EDN1,ENPP2,ERAP2,EXO1,FAS,FCN1,FGL1,FGL2,FYB1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR183,GPR31,GRAMD4,GSDMD,GTPBP1,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HRH2,ICAM1,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IGSF6,IL12A,IL12RB1,IL15,IL18BP,IL1RN,IL27,IL31RA,IL32,IL4I1,IRF1,IRF7,ISG20,ITK,JAK2,JAK3,KARS1,KLRK1,LAG3,LAMP3,LILRA1,LILRA2,LILRB3,LITAF,LY75,LYN,MCOLN2,MEFV,MSRB1,NCF1,NLRC5,NMI,NOD2,NUB1,OAS2,OPTN,OSM,P2RX7,PARP14,PDCD1,PDCD1LG2,PDE4B,PLPP4,PML,PSMB10,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RSAD2,S100A13,SBNO2,SCIMP,SECTM1,SERINC5,SERPING1,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SOCS1,STAP1,STAT1,STAT2,SUCNR1,TAP1,TAP2,TAPBP,TAPBPL,TBX21,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF11A,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TRAFD1,TRIM17,TRIM22,TRIM31,UBD,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0030174","Term":"regulation of DNA-templated DNA replication initiation","Annotated":14,"Significant":7,"Expected":0.77,"Rank in p.value_classic":237,"p.value_elim":3.6e-06,"p.value_classic":3.7e-06,"Genes":"CDT1,MCM2,MCM4,MCM5,MCM6,MCM7,TICRR"} {"Genesets":"GO:0030593","Term":"neutrophil chemotaxis","Annotated":87,"Significant":17,"Expected":4.8,"Rank in p.value_classic":240,"p.value_elim":4.1e-06,"p.value_classic":4.4e-06,"Genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,EDN1,NOD2,PDE4B,TNFAIP6"} {"Genesets":"GO:2000425","Term":"regulation of apoptotic cell clearance","Annotated":10,"Significant":6,"Expected":0.55,"Rank in p.value_classic":241,"p.value_elim":4.7e-06,"p.value_classic":4.8e-06,"Genes":"C2,C3,C4A,C4B,CD300LF,TGM2"} {"Genesets":"GO:0042102","Term":"positive regulation of T cell proliferation","Annotated":88,"Significant":19,"Expected":4.86,"Rank in p.value_classic":168,"p.value_elim":1e-05,"p.value_classic":2.4e-07,"Genes":"CCL5,CD274,CD28,CD80,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-E,IL12RB1,IL15,JAK2,JAK3,KITLG,PDCD1LG2,RIPK2,SLAMF1,TNFSF13B,VCAM1"} {"Genesets":"GO:0071222","Term":"cellular response to lipopolysaccharide","Annotated":177,"Significant":25,"Expected":9.77,"Rank in p.value_classic":271,"p.value_elim":0.00001,"p.value_classic":0.00001,"Genes":"ACOD1,CARD16,CCL5,CD274,CD80,CMPK2,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,JAK2,KLRK1,LILRA2,LITAF,LYN,NOD2,PDCD1LG2,PDE4B,RIPK2,SBNO2,SCIMP,STAP1,TICAM2,ZC3H12A"} {"Genesets":"GO:0042832","Term":"defense response to protozoan","Annotated":22,"Significant":8,"Expected":1.21,"Rank in p.value_classic":265,"p.value_elim":0.00001,"p.value_classic":0.00001,"Genes":"BATF2,CD40,GBP2,GBP4,GBP6,GBP7,SLC11A1,TSPAN32"} {"Genesets":"GO:0006268","Term":"DNA unwinding involved in DNA replication","Annotated":22,"Significant":8,"Expected":1.21,"Rank in p.value_classic":266,"p.value_elim":0.00001,"p.value_classic":0.00001,"Genes":"CDC45,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,RECQL4"} {"Genesets":"GO:0050852","Term":"T cell receptor signaling pathway","Annotated":105,"Significant":18,"Expected":5.8,"Rank in p.value_classic":274,"p.value_elim":0.00002,"p.value_classic":0.00002,"Genes":"BTN2A2,BTN3A1,BTN3A2,BTN3A3,CD28,CEACAM1,CTLA4,FYB1,GBP1,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,ITK,PDE4B,RIPK2,TNFRSF21,ZC3H12A"} {"Genesets":"GO:0007186","Term":"G protein-coupled receptor signaling pathway","Annotated":522,"Significant":52,"Expected":28.82,"Rank in p.value_classic":281,"p.value_elim":0.00002,"p.value_classic":0.00002,"Genes":"ADGRE5,ADGRG5,ADORA3,AGT,C3,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CELSR1,CISH,CX3CR1,CXCL10,CXCL11,CXCL9,CXCR3,CYSLTR1,CYSLTR2,DYNLT1,ECEL1,EDN1,F2RL3,FCN1,GHRL,GNG2,GPR183,GPR31,GRM8,HCAR2,HCAR3,HRH2,IGF2R,JAK2,NECAB2,NPR1,NXPH2,P2RY14,PDE3B,PDE4B,PLEK,PTGER4,RAPGEF2,RGS18,RXFP1,S1PR1,SSTR2,STMN1,SUCNR1,TGM2"} {"Genesets":"GO:0050729","Term":"positive regulation of inflammatory response","Annotated":129,"Significant":24,"Expected":7.12,"Rank in p.value_classic":164,"p.value_elim":0.00003,"p.value_classic":1.3e-07,"Genes":"ADAM8,AGT,AIM2,C3,CASP4,CD28,HLA-E,IDO1,IFI35,IL15,JAK2,KARS1,LRRK2,NLRP12,NMI,OSM,PTGER4,STAP1,SUCNR1,TLR10,TLR7,TNFRSF11A,TNFSF18,ZBP1"} {"Genesets":"GO:0032731","Term":"positive regulation of interleukin-1 beta production","Annotated":55,"Significant":12,"Expected":3.04,"Rank in p.value_classic":294,"p.value_elim":0.00003,"p.value_classic":0.00004,"Genes":"AIM2,GBP5,GSDMD,JAK2,LILRA2,MEFV,NLRP12,NOD2,P2RX7,PYHIN1,RIPK2,TLR8"} {"Genesets":"GO:0050766","Term":"positive regulation of phagocytosis","Annotated":58,"Significant":12,"Expected":3.2,"Rank in p.value_classic":312,"p.value_elim":0.00006,"p.value_classic":0.00006,"Genes":"APPL2,C2,C3,C4A,C4B,CD300LF,FCN1,IL15,IL15RA,NOD2,SLC11A1,STAP1"} {"Genesets":"GO:0035455","Term":"response to interferon-alpha","Annotated":20,"Significant":7,"Expected":1.1,"Rank in p.value_classic":313,"p.value_elim":0.00006,"p.value_classic":0.00006,"Genes":"IFIT2,IFIT3,IFITM1,IFITM2,IFITM3,LAMP3,PYHIN1"} {"Genesets":"GO:0045591","Term":"positive regulation of regulatory T cell differentiation","Annotated":20,"Significant":7,"Expected":1.1,"Rank in p.value_classic":314,"p.value_elim":0.00006,"p.value_classic":0.00006,"Genes":"BCL6,BTN2A2,HLA-DRA,HLA-DRB1,HLA-G,IL4I1,SOCS1"} {"Genesets":"GO:0048247","Term":"lymphocyte chemotaxis","Annotated":47,"Significant":13,"Expected":2.59,"Rank in p.value_classic":214,"p.value_elim":0.00007,"p.value_classic":9.8e-07,"Genes":"ADAM8,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CXCL10,CXCL11,GPR183,HSD3B7,KLRK1,PADI2"} {"Genesets":"GO:0045089","Term":"positive regulation of innate immune response","Annotated":114,"Significant":24,"Expected":6.29,"Rank in p.value_classic":144,"p.value_elim":0.00007,"p.value_classic":1.1e-08,"Genes":"ADAM8,AIM2,CCL5,CLEC6A,FCN1,GBP5,HLA-E,HLA-F,HLA-G,IFI35,IL12A,IRF7,KLRK1,LAG3,LILRA2,LYN,NLRC5,NMI,NOD2,PYHIN1,SLAMF6,TLR8,ZBP1,ZNFX1"} {"Genesets":"GO:0002573","Term":"myeloid leukocyte differentiation","Annotated":185,"Significant":24,"Expected":10.21,"Rank in p.value_classic":322,"p.value_elim":0.00008,"p.value_classic":0.00008,"Genes":"BATF2,BATF3,CD101,CD74,CEACAM1,GPR183,HLA-DRB1,IL15,IL31RA,IRF7,KITLG,LILRB3,LYN,MMP9,RELB,SBNO2,SH3PXD2A,SNX10,SOCS1,TAL1,TESC,TNFAIP6,TNFRSF11A,UBD"} {"Genesets":"GO:0042531","Term":"positive regulation of tyrosine phosphorylation of STAT protein","Annotated":43,"Significant":10,"Expected":2.37,"Rank in p.value_classic":326,"p.value_elim":0.00009,"p.value_classic":0.00009,"Genes":"CCL5,CD40,IL12A,IL15,IL31RA,JAK2,LYN,OSM,PARP14,TNFSF18"} {"Genesets":"GO:0060333","Term":"interferon-gamma-mediated signaling pathway","Annotated":21,"Significant":7,"Expected":1.16,"Rank in p.value_classic":324,"p.value_elim":0.00009,"p.value_classic":0.00009,"Genes":"IRF1,JAK2,NLRC5,NMI,PARP14,SOCS1,STAT1"} {"Genesets":"GO:0002478","Term":"antigen processing and presentation of exogenous peptide antigen","Annotated":36,"Significant":20,"Expected":1.99,"Rank in p.value_classic":39,"p.value_elim":0.00009,"p.value_classic":1.7e-16,"Genes":"B2M,CD74,CTSS,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,TAP1,TAP2"} {"Genesets":"GO:0071347","Term":"cellular response to interleukin-1","Annotated":89,"Significant":15,"Expected":4.91,"Rank in p.value_classic":331,"p.value_elim":0.00009,"p.value_classic":0.0001,"Genes":"ACOD1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,EDN1,GBP1,GBP2,GBP3,IL1RN,ZBP1,ZC3H12A"} {"Genesets":"GO:0043380","Term":"regulation of memory T cell differentiation","Annotated":10,"Significant":5,"Expected":0.55,"Rank in p.value_classic":333,"p.value_elim":0.0001,"p.value_classic":0.0001,"Genes":"BCL6,FGL2,HLA-DRA,HLA-DRB1,IL12RB1"} {"Genesets":"GO:0042130","Term":"negative regulation of T cell proliferation","Annotated":53,"Significant":11,"Expected":2.93,"Rank in p.value_classic":347,"p.value_elim":0.00012,"p.value_classic":0.00012,"Genes":"BTN2A2,CD274,CD80,CTLA4,HLA-DRB1,HLA-G,IDO1,IL4I1,PDCD1LG2,TNFRSF21,TSPAN32"} {"Genesets":"GO:0002710","Term":"negative regulation of T cell mediated immunity","Annotated":22,"Significant":7,"Expected":1.21,"Rank in p.value_classic":349,"p.value_elim":0.00012,"p.value_classic":0.00012,"Genes":"CEACAM1,HLA-F,HLA-G,IL4I1,NOD2,SLAMF1,TBX21"} {"Genesets":"GO:0002281","Term":"macrophage activation involved in immune response","Annotated":16,"Significant":6,"Expected":0.88,"Rank in p.value_classic":355,"p.value_elim":0.00013,"p.value_classic":0.00014,"Genes":"CX3CR1,DYSF,IFI35,NMI,SBNO2,SUCNR1"} {"Genesets":"GO:0000076","Term":"DNA replication checkpoint signaling","Annotated":16,"Significant":6,"Expected":0.88,"Rank in p.value_classic":356,"p.value_elim":0.00013,"p.value_classic":0.00014,"Genes":"CDC45,CDC6,CDT1,CLSPN,ORC1,TICRR"} {"Genesets":"GO:0009617","Term":"response to bacterium","Annotated":466,"Significant":74,"Expected":25.73,"Rank in p.value_classic":36,"p.value_elim":0.00018,"p.value_classic":7.9e-17,"Genes":"ACOD1,B2M,BANK1,C15orf48,C2,C3,C4B,CARD16,CASP4,CCL5,CD274,CD80,CFB,CMPK2,COLEC12,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,EDN1,FAM20A,GBP2,GBP4,GBP5,GBP6,GBP7,GCH1,GPR31,GSDMA,GSDMD,H2BC21,HLA-A,HLA-B,HLA-DRB1,HLA-E,IDO1,IL12A,IL12RB2,IL18BP,IL27,JAK2,KLRK1,LILRA2,LITAF,LYN,NOD2,OAS2,OPTN,P2RX7,PDCD1LG2,PDE4B,PLAAT3,PTGER4,RIPK2,RNF213,SBNO2,SCIMP,SLAMF8,SLC11A1,STAP1,TAP2,THBD,TICAM2,TLR5,TMEM255A,TNFRSF11A,TNFSF8,TRDN,VCAM1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0032496","Term":"response to lipopolysaccharide","Annotated":263,"Significant":39,"Expected":14.52,"Rank in p.value_classic":148,"p.value_elim":0.00018,"p.value_classic":1.5e-08,"Genes":"ACOD1,CARD16,CCL5,CD274,CD80,CMPK2,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,EDN1,GCH1,IDO1,IL12A,IL12RB2,IL18BP,JAK2,KLRK1,LILRA2,LITAF,LYN,NOD2,P2RX7,PDCD1LG2,PDE4B,PTGER4,RIPK2,SBNO2,SCIMP,SLC11A1,STAP1,THBD,TICAM2,TNFRSF11A,VCAM1,ZC3H12A"} {"Genesets":"GO:0070371","Term":"ERK1 and ERK2 cascade","Annotated":260,"Significant":35,"Expected":14.35,"Rank in p.value_classic":205,"p.value_elim":0.00019,"p.value_classic":8.8e-07,"Genes":"AGT,ATF3,BTN2A2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD74,CDK1,CEACAM1,DAB2,EDN1,GBP1,GLIPR2,GPR183,HESX1,HLA-DRB1,ICAM1,IQGAP3,KARS1,LYN,MIR503,NECAB2,NLRP12,NOD2,NRP1,PTGER4,RAPGEF2,RIPK2,SCIMP,SLAMF1,TNFAIP8L3,TNFRSF11A"} {"Genesets":"GO:0045953","Term":"negative regulation of natural killer cell mediated cytotoxicity","Annotated":17,"Significant":6,"Expected":0.94,"Rank in p.value_classic":376,"p.value_elim":0.0002,"p.value_classic":0.0002,"Genes":"CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G"} {"Genesets":"GO:0045954","Term":"positive regulation of natural killer cell mediated cytotoxicity","Annotated":17,"Significant":6,"Expected":0.94,"Rank in p.value_classic":377,"p.value_elim":0.0002,"p.value_classic":0.0002,"Genes":"HLA-E,HLA-F,IL12A,KLRK1,LAG3,SLAMF6"} {"Genesets":"GO:0051984","Term":"positive regulation of chromosome segregation","Annotated":24,"Significant":7,"Expected":1.33,"Rank in p.value_classic":387,"p.value_elim":0.00022,"p.value_classic":0.00023,"Genes":"AURKB,BIRC5,CDC6,CDT1,NCAPG,NCAPG2,NCAPH"} {"Genesets":"GO:0032693","Term":"negative regulation of interleukin-10 production","Annotated":18,"Significant":6,"Expected":0.99,"Rank in p.value_classic":399,"p.value_elim":0.00028,"p.value_classic":0.00029,"Genes":"CD274,DLL1,IDO1,JAK3,PDCD1LG2,TNFRSF21"} {"Genesets":"GO:0046597","Term":"negative regulation of viral entry into host cell","Annotated":18,"Significant":6,"Expected":0.99,"Rank in p.value_classic":400,"p.value_elim":0.00028,"p.value_classic":0.00029,"Genes":"CIITA,FCN1,IFITM1,IFITM2,IFITM3,TRIM31"} {"Genesets":"GO:0006959","Term":"humoral immune response","Annotated":128,"Significant":32,"Expected":7.07,"Rank in p.value_classic":59,"p.value_elim":0.00037,"p.value_classic":2.7e-13,"Genes":"ACOD1,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL13,CD28,CFB,CFH,CR1L,CXCL10,CXCL11,CXCL5,CXCL9,EXO1,FCN1,GPR183,H2BC21,HLA-A,HLA-DQB1,HLA-DRB1,HLA-E,NOD2,PDCD1,PSMB10,SERPING1,SLC11A1,TNFRSF21"} {"Genesets":"GO:0098792","Term":"xenophagy","Annotated":13,"Significant":5,"Expected":0.72,"Rank in p.value_classic":423,"p.value_elim":0.00044,"p.value_classic":0.00045,"Genes":"CALCOCO2,NOD2,OPTN,RIPK2,RNF213"} {"Genesets":"GO:0001961","Term":"positive regulation of cytokine-mediated signaling pathway","Annotated":52,"Significant":10,"Expected":2.87,"Rank in p.value_classic":424,"p.value_elim":0.00045,"p.value_classic":0.00047,"Genes":"CASP4,CD300LF,CD74,EDN1,IRF7,NLRC5,PARP14,RIPK2,TICAM2,ZBP1"} {"Genesets":"GO:0016525","Term":"negative regulation of angiogenesis","Annotated":82,"Significant":13,"Expected":4.53,"Rank in p.value_classic":430,"p.value_elim":0.00049,"p.value_classic":0.00052,"Genes":"AGT,AMOT,CXCL10,E2F2,GHRL,HLA-G,KLF4,MIR503,NPR1,PDE3B,PML,STAT1,THBS2"} {"Genesets":"GO:0050731","Term":"positive regulation of peptidyl-tyrosine phosphorylation","Annotated":148,"Significant":25,"Expected":8.17,"Rank in p.value_classic":189,"p.value_elim":0.00053,"p.value_classic":5e-07,"Genes":"AGT,BANK1,CCL5,CD40,CD74,CD80,CLEC6A,ENPP2,GHRL,HBEGF,HGF,IL12A,IL15,IL31RA,JAK2,KITLG,LYN,NCF1,NOD2,NRP1,OSM,PARP14,RIPK2,STAP1,TNFSF18"} {"Genesets":"GO:0032727","Term":"positive regulation of interferon-alpha production","Annotated":20,"Significant":6,"Expected":1.1,"Rank in p.value_classic":435,"p.value_elim":0.00054,"p.value_classic":0.00055,"Genes":"IFIH1,IRF7,RIPK2,STAT1,TLR7,TLR8"} {"Genesets":"GO:0070269","Term":"pyroptosis","Annotated":20,"Significant":6,"Expected":1.1,"Rank in p.value_classic":436,"p.value_elim":0.00054,"p.value_classic":0.00055,"Genes":"AIM2,CASP4,GSDMA,GSDMD,MEFV,ZBP1"} {"Genesets":"GO:0002230","Term":"positive regulation of defense response to virus by host","Annotated":28,"Significant":7,"Expected":1.55,"Rank in p.value_classic":443,"p.value_elim":0.00063,"p.value_classic":0.00065,"Genes":"AIM2,APOBEC3G,DTX3L,IL12RB1,IL27,STAT1,ZC3H12A"} {"Genesets":"GO:0050870","Term":"positive regulation of T cell activation","Annotated":215,"Significant":40,"Expected":11.87,"Rank in p.value_classic":78,"p.value_elim":0.00064,"p.value_classic":8.7e-12,"Genes":"ADAM8,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IL12A,IL12RB1,IL15,IL4I1,JAK2,JAK3,KITLG,KLRK1,LYN,NOD2,PDCD1LG2,RIPK2,SLAMF1,SOCS1,TNFSF13B,VCAM1"} {"Genesets":"GO:1902969","Term":"mitotic DNA replication","Annotated":14,"Significant":5,"Expected":0.77,"Rank in p.value_classic":446,"p.value_elim":0.00065,"p.value_classic":0.00067,"Genes":"BCL6,CDC45,MCM2,MCM4,MCM6"} {"Genesets":"GO:0070374","Term":"positive regulation of ERK1 and ERK2 cascade","Annotated":164,"Significant":20,"Expected":9.05,"Rank in p.value_classic":449,"p.value_elim":0.00066,"p.value_classic":0.00071,"Genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD74,GLIPR2,GPR183,HLA-DRB1,ICAM1,NECAB2,NOD2,NRP1,RAPGEF2,RIPK2,SCIMP,SLAMF1,TNFAIP8L3,TNFRSF11A"} {"Genesets":"GO:0034143","Term":"regulation of toll-like receptor 4 signaling pathway","Annotated":21,"Significant":6,"Expected":1.16,"Rank in p.value_classic":451,"p.value_elim":0.00071,"p.value_classic":0.00074,"Genes":"ACOD1,APPL2,IFI35,LILRA2,LYN,TICAM2"} {"Genesets":"GO:0035458","Term":"cellular response to interferon-beta","Annotated":21,"Significant":6,"Expected":1.16,"Rank in p.value_classic":452,"p.value_elim":0.00071,"p.value_classic":0.00074,"Genes":"ACOD1,AIM2,IFITM2,IRF1,PYHIN1,STAT1"} {"Genesets":"GO:0002376","Term":"immune system process","Annotated":2025,"Significant":272,"Expected":111.8,"Rank in p.value_classic":2,"p.value_elim":0.00075,"Genes":"ACOD1,ADAM8,ADGRE5,AIM2,ALAS1,ANLN,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,ASB2,B2M,BANK1,BATF2,BATF3,BCL2L11,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD101,CD1A,CD1C,CD274,CD28,CD300H,CD300LF,CD38,CD40,CD7,CD74,CD80,CD93,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CR1L,CSF2RB,CTLA4,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,CYSLTR2,DDX60,DLL1,DTX3L,DYSF,EDA,EDN1,ENPP2,EPAS1,EPHB3,ERAP2,ESCO2,EXO1,FAS,FAXDC2,FCN1,FGL1,FGL2,FLT3LG,FYB1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR183,GPR31,GRAMD4,GSDMD,GTPBP1,H2BC21,HCAR2,HELLS,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HRH2,HSD3B7,ICAM1,IDO1,IDO2,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IGSF6,IL12A,IL12RB1,IL15,IL15RA,IL18BP,IL1RN,IL27,IL31RA,IL32,IL4I1,IRF1,IRF7,ISG20,ITGA7,ITK,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LAG3,LAMP3,LILRA1,LILRA2,LILRB3,LITAF,LRP5,LRRK2,LY75,LYN,LYVE1,MAF,MCOLN2,MEFV,MMP9,MSRB1,NCAPG2,NCF1,NLRC5,NLRP12,NMI,NOD2,NUB1,OAS2,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PDCD1,PDCD1LG2,PDE4B,PIM1,PLEK,PLPP4,PMAIP1,PML,POLB,PSMB10,PSMB8,PSMB9,PSME1,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RNF213,RSAD2,S100A13,S1PR1,SBNO2,SCIMP,SCIN,SECTM1,SELL,SERINC5,SERPING1,SGPL1,SH3PXD2A,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SNX10,SOCS1,SSBP3,STAP1,STAT1,STAT2,SUCNR1,TAL1,TAP1,TAP2,TAPBP,TAPBPL,TBX21,TESC,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TOP2A,TRAFD1,TRIM17,TRIM22,TRIM31,TSPAN32,UBD,VCAM1,VEGFC,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0045581","Term":"negative regulation of T cell differentiation","Annotated":37,"Significant":11,"Expected":2.04,"Rank in p.value_classic":233,"p.value_elim":0.00091,"p.value_classic":3.1e-06,"Genes":"BCL6,CD74,CTLA4,FGL2,IRF1,JAK3,LAG3,SOCS1,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0051770","Term":"positive regulation of nitric-oxide synthase biosynthetic process","Annotated":15,"Significant":5,"Expected":0.83,"Rank in p.value_classic":463,"p.value_elim":0.00093,"p.value_classic":0.00096,"Genes":"JAK2,JAK3,LRRK2,NOD2,STAT1"} {"Genesets":"GO:0002827","Term":"positive regulation of T-helper 1 type immune response","Annotated":15,"Significant":5,"Expected":0.83,"Rank in p.value_classic":464,"p.value_elim":0.00093,"p.value_classic":0.00096,"Genes":"IL12RB1,RIPK2,SLAMF1,SLC11A1,TBX21"} {"Genesets":"GO:0002837","Term":"regulation of immune response to tumor cell","Annotated":15,"Significant":5,"Expected":0.83,"Rank in p.value_classic":465,"p.value_elim":0.00093,"p.value_classic":0.00096,"Genes":"CD274,CEACAM1,HLA-DRB1,IL12A,IL4I1"} {"Genesets":"GO:0045623","Term":"negative regulation of T-helper cell differentiation","Annotated":15,"Significant":5,"Expected":0.83,"Rank in p.value_classic":466,"p.value_elim":0.00093,"p.value_classic":0.00096,"Genes":"BCL6,JAK3,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0002755","Term":"MyD88-dependent toll-like receptor signaling pathway","Annotated":22,"Significant":6,"Expected":1.21,"Rank in p.value_classic":468,"p.value_elim":0.00094,"p.value_classic":0.00097,"Genes":"CD300LF,IRF1,IRF7,TLR10,TLR5,TLR8"} {"Genesets":"GO:0050728","Term":"negative regulation of inflammatory response","Annotated":122,"Significant":16,"Expected":6.74,"Rank in p.value_classic":475,"p.value_elim":0.00102,"p.value_classic":0.00108,"Genes":"ACOD1,CDH5,CYLD,GHRL,GPR31,HGF,HLA-DRB1,IL22RA2,KLF4,LYN,MEFV,NLRP12,NOD2,PTGER4,SLAMF8,TNFAIP6"} {"Genesets":"GO:0060337","Term":"type I interferon signaling pathway","Annotated":58,"Significant":10,"Expected":3.2,"Rank in p.value_classic":481,"p.value_elim":0.00111,"p.value_classic":0.00116,"Genes":"IFI27,IFITM1,IFITM2,IFITM3,IRF7,NLRC5,OAS2,STAT1,STAT2,ZBP1"} {"Genesets":"GO:0019221","Term":"cytokine-mediated signaling pathway","Annotated":388,"Significant":61,"Expected":21.42,"Rank in p.value_classic":50,"p.value_elim":0.00111,"p.value_classic":7.7e-14,"Genes":"ACSL1,AIM2,APPL2,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD300LF,CD74,CEACAM1,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,EDN1,FAS,IFI27,IFITM1,IFITM2,IFITM3,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL31RA,IL3RA,IRF1,IRF7,JAK2,JAK3,LILRA1,LILRA2,LILRB3,LYN,NLRC5,NMI,OAS2,OSM,PADI2,PARP14,RIPK2,SOCS1,STAP1,STAT1,STAT2,TICAM2,TNFRSF11A,TNFSF13B,TNFSF18,ZBP1"} {"Genesets":"GO:0032816","Term":"positive regulation of natural killer cell activation","Annotated":23,"Significant":6,"Expected":1.27,"Rank in p.value_classic":485,"p.value_elim":0.00121,"p.value_classic":0.00125,"Genes":"HLA-E,HLA-F,IL12A,IL15,IL15RA,JAK2"} {"Genesets":"GO:0032691","Term":"negative regulation of interleukin-1 beta production","Annotated":23,"Significant":6,"Expected":1.27,"Rank in p.value_classic":486,"p.value_elim":0.00121,"p.value_classic":0.00125,"Genes":"CARD16,CX3CR1,GHRL,MEFV,PML,ZC3H12A"} {"Genesets":"GO:0090025","Term":"regulation of monocyte chemotaxis","Annotated":23,"Significant":6,"Expected":1.27,"Rank in p.value_classic":487,"p.value_elim":0.00121,"p.value_classic":0.00125,"Genes":"CCL5,CX3CR1,CXCL10,LYN,SLAMF8,TNFSF18"} {"Genesets":"GO:1901223","Term":"negative regulation of NIK/NF-kappaB signaling","Annotated":23,"Significant":6,"Expected":1.27,"Rank in p.value_classic":488,"p.value_elim":0.00121,"p.value_classic":0.00125,"Genes":"CYLD,IFI35,LITAF,NLRP12,NMI,ZC3H12A"} {"Genesets":"GO:0000819","Term":"sister chromatid segregation","Annotated":219,"Significant":29,"Expected":12.09,"Rank in p.value_classic":258,"p.value_elim":0.00128,"p.value_classic":1e-05,"Genes":"AURKB,BIRC5,BUB1B,CDC6,CDCA5,CDT1,CENPK,CHMP4C,DSCC1,EML4,ESCO2,FEN1,HORMAD1,KIF11,KIF18B,MAD2L1,MEIKIN,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,PRC1,RMI2,SPC24,SPC25,TOP2A,ZWINT"} {"Genesets":"GO:0045589","Term":"regulation of regulatory T cell differentiation","Annotated":30,"Significant":11,"Expected":1.66,"Rank in p.value_classic":173,"p.value_elim":0.00141,"p.value_classic":2.8e-07,"Genes":"BCL6,BTN2A2,CD28,CTLA4,HLA-DRA,HLA-DRB1,HLA-G,IL4I1,IRF1,LAG3,SOCS1"} {"Genesets":"GO:0007586","Term":"digestion","Annotated":70,"Significant":11,"Expected":3.86,"Rank in p.value_classic":501,"p.value_elim":0.00141,"p.value_classic":0.00147,"Genes":"GCNT3,GHRL,HRH2,NOD2,PGA3,PGA4,PGA5,SLC2A5,SNX10,TIFAB,TYMP"} {"Genesets":"GO:0032675","Term":"regulation of interleukin-6 production","Annotated":126,"Significant":16,"Expected":6.96,"Rank in p.value_classic":507,"p.value_elim":0.00145,"p.value_classic":0.00153,"Genes":"BANK1,CD74,GHRL,HGF,HLA-B,IFIH1,LILRA2,NLRP12,NOD2,P2RX7,RIPK2,SCIMP,SLAMF1,TLR7,TLR8,ZC3H12A"} {"Genesets":"GO:0070673","Term":"response to interleukin-18","Annotated":10,"Significant":4,"Expected":0.55,"Rank in p.value_classic":502,"p.value_elim":0.00145,"p.value_classic":0.00148,"Genes":"CASP4,CYLD,RIPK2,TICAM2"} {"Genesets":"GO:0002604","Term":"regulation of dendritic cell antigen processing and presentation","Annotated":10,"Significant":4,"Expected":0.55,"Rank in p.value_classic":503,"p.value_elim":0.00145,"p.value_classic":0.00148,"Genes":"CD74,FGL2,NOD2,SLC11A1"} {"Genesets":"GO:0045625","Term":"regulation of T-helper 1 cell differentiation","Annotated":10,"Significant":4,"Expected":0.55,"Rank in p.value_classic":504,"p.value_elim":0.00145,"p.value_classic":0.00148,"Genes":"CD80,IL27,JAK3,RIPK2"} {"Genesets":"GO:0060907","Term":"positive regulation of macrophage cytokine production","Annotated":24,"Significant":6,"Expected":1.33,"Rank in p.value_classic":511,"p.value_elim":0.00154,"p.value_classic":0.00158,"Genes":"CD74,HLA-G,NOD2,P2RX7,RIPK2,TLR7"} {"Genesets":"GO:0042129","Term":"regulation of T cell proliferation","Annotated":150,"Significant":32,"Expected":8.28,"Rank in p.value_classic":91,"p.value_elim":0.00154,"p.value_classic":2.6e-11,"Genes":"BCL6,BTN2A2,CCL5,CD274,CD28,CD80,CTLA4,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12RB1,IL15,IL27,IL4I1,IRF1,JAK2,JAK3,KITLG,PDCD1LG2,RIPK2,SLAMF1,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"Genesets":"GO:0001818","Term":"negative regulation of cytokine production","Annotated":231,"Significant":36,"Expected":12.75,"Rank in p.value_classic":147,"p.value_elim":0.00161,"p.value_classic":1.4e-08,"Genes":"ACOD1,APPL2,BANK1,BCL6,BTN2A2,CARD16,CD274,CEACAM1,CX3CR1,CYLD,DLL1,GBP1,GBP7,GHRL,HGF,HLA-DRB1,HLA-F,IDO1,IL12A,JAK3,KLF4,LAG3,MEFV,NLRP12,NMI,NOD2,PDCD1LG2,PML,PTGER4,RELB,SLAMF1,SLC11A1,TBX21,TLR8,TNFRSF21,ZC3H12A"} {"Genesets":"GO:0008283","Term":"cell population proliferation","Annotated":1560,"Significant":135,"Expected":86.13,"Rank in p.value_classic":155,"p.value_elim":0.00172,"p.value_classic":3.8e-08,"Genes":"ABCB1,ADORA3,AGT,APPL2,ASCL2,ATF3,ATF5,AURKB,B2M,BCL6,BIRC5,BTN2A2,BTN3A1,CCL5,CCL8,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CEACAM1,CHRD,COMP,CSF2RB,CTLA4,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,DAB2,DLL1,E2F1,E2F8,EDN1,FGL1,FLT3LG,GHRL,GLUL,GNG2,GPR183,HAPLN3,HBEGF,HELLS,HGF,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IFI35,IFIT3,IFITM1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IQGAP3,IRF1,JAK2,JAK3,KITLG,KLF4,LBH,LRP5,LRRK2,LYN,MARCKSL1,MCM10,MCM7,MIR503,MMP9,MTSS1,NCAPG2,NMI,NOD2,NPR1,NRP1,OCA2,OSM,OVOL1,P2RX7,PARP10,PDCD1LG2,PID1,PIM1,PLAAT4,PLCD3,PML,PRC1,PSMB10,RAPGEF2,RASGRF1,RIPK2,S100A13,S1PR1,SCIN,SHCBP1,SIDT2,SLAMF1,SLC11A1,SOX17,SSBP3,SSTR2,STAT1,STAT2,TACC2,TESC,TMEM119,TNFRSF11A,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,UHRF1,VCAM1,VEGFC,WARS1"} {"Genesets":"GO:2001185","Term":"regulation of CD8-positive, alpha-beta T cell activation","Annotated":17,"Significant":5,"Expected":0.94,"Rank in p.value_classic":519,"p.value_elim":0.00175,"p.value_classic":0.00179,"Genes":"CD274,HLA-A,HLA-E,IRF1,SOCS1"} {"Genesets":"GO:0002643","Term":"regulation of tolerance induction","Annotated":17,"Significant":5,"Expected":0.94,"Rank in p.value_classic":520,"p.value_elim":0.00175,"p.value_classic":0.00179,"Genes":"CD274,HLA-B,HLA-G,IDO1,PDCD1"} {"Genesets":"GO:0032695","Term":"negative regulation of interleukin-12 production","Annotated":17,"Significant":5,"Expected":0.94,"Rank in p.value_classic":521,"p.value_elim":0.00175,"p.value_classic":0.00179,"Genes":"JAK3,MEFV,NOD2,SLAMF1,TLR8"} {"Genesets":"GO:0045124","Term":"regulation of bone resorption","Annotated":33,"Significant":7,"Expected":1.82,"Rank in p.value_classic":522,"p.value_elim":0.00178,"p.value_classic":0.00184,"Genes":"ADAM8,CD38,P2RX7,PDK4,S1PR1,TMEM119,TNFRSF11A"} {"Genesets":"GO:1905820","Term":"positive regulation of chromosome separation","Annotated":25,"Significant":6,"Expected":1.38,"Rank in p.value_classic":526,"p.value_elim":0.00193,"p.value_classic":0.00199,"Genes":"AURKB,BIRC5,CDT1,NCAPG,NCAPG2,NCAPH"} {"Genesets":"GO:0032103","Term":"positive regulation of response to external stimulus","Annotated":370,"Significant":60,"Expected":20.43,"Rank in p.value_classic":47,"p.value_elim":0.00205,"p.value_classic":3e-14,"Genes":"ACOD1,ADAM8,AGT,AIM2,C3,CASP4,CCL5,CCL7,CD28,CD74,CLEC6A,CX3CR1,CXCL10,DDX60,EDN1,FCN1,GBP5,GHRL,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IL12A,IL15,IRF7,JAK2,KARS1,KLRK1,LAG3,LILRA2,LRRK2,LYN,NLRC5,NLRP12,NMI,NOD2,NRP1,OPTN,OSM,P2RX4,PTGER4,PYHIN1,RIPK2,S1PR1,SCARF1,SCIMP,SLAMF1,SLAMF6,STAP1,SUCNR1,THBD,TLR10,TLR7,TLR8,TNFRSF11A,TNFSF18,VEGFC,ZBP1,ZNFX1"} {"Genesets":"GO:0061844","Term":"antimicrobial humoral immune response mediated by antimicrobial peptide","Annotated":34,"Significant":7,"Expected":1.88,"Rank in p.value_classic":535,"p.value_elim":0.00214,"p.value_classic":0.00221,"Genes":"CCL13,CXCL10,CXCL11,CXCL5,CXCL9,H2BC21,NOD2"} {"Genesets":"GO:0032308","Term":"positive regulation of prostaglandin secretion","Annotated":11,"Significant":4,"Expected":0.61,"Rank in p.value_classic":540,"p.value_elim":0.00218,"p.value_classic":0.00223,"Genes":"EDN1,P2RX4,P2RX7,TNFRSF11A"} {"Genesets":"GO:2000508","Term":"regulation of dendritic cell chemotaxis","Annotated":11,"Significant":4,"Expected":0.61,"Rank in p.value_classic":541,"p.value_elim":0.00218,"p.value_classic":0.00223,"Genes":"IL12A,SLAMF1,SLAMF8,TNFSF18"} {"Genesets":"GO:1990830","Term":"cellular response to leukemia inhibitory factor","Annotated":85,"Significant":12,"Expected":4.69,"Rank in p.value_classic":546,"p.value_elim":0.00225,"p.value_classic":0.00236,"Genes":"HELLS,ICAM1,INA,KLF4,MRAS,MYBL2,PADI2,PML,SBNO2,SNX10,SOX17,VEGFC"} {"Genesets":"GO:0002689","Term":"negative regulation of leukocyte chemotaxis","Annotated":18,"Significant":5,"Expected":0.99,"Rank in p.value_classic":547,"p.value_elim":0.00232,"p.value_classic":0.00237,"Genes":"KLRK1,PADI2,SLAMF8,STAP1,TNFAIP6"} {"Genesets":"GO:0045822","Term":"negative regulation of heart contraction","Annotated":18,"Significant":5,"Expected":0.99,"Rank in p.value_classic":548,"p.value_elim":0.00232,"p.value_classic":0.00237,"Genes":"GJD3,JAK2,SPTBN4,SRI,ZC3H12A"} {"Genesets":"GO:0007204","Term":"positive regulation of cytosolic calcium ion concentration","Annotated":132,"Significant":16,"Expected":7.29,"Rank in p.value_classic":553,"p.value_elim":0.00235,"p.value_classic":0.00249,"Genes":"AGT,CCRL2,CD38,CX3CR1,CXCR3,CYSLTR1,EDN1,F2RL3,GHRL,JAK2,JAK3,P2RX4,P2RX7,PML,PTGER4,S1PR1"} {"Genesets":"GO:0071398","Term":"cellular response to fatty acid","Annotated":26,"Significant":6,"Expected":1.44,"Rank in p.value_classic":550,"p.value_elim":0.0024,"p.value_classic":0.00247,"Genes":"DGAT2,E2F1,EDN1,PDK4,PID1,ZC3H12A"} {"Genesets":"GO:0002027","Term":"regulation of heart rate","Annotated":75,"Significant":11,"Expected":4.14,"Rank in p.value_classic":557,"p.value_elim":0.00249,"p.value_classic":0.0026,"Genes":"AGT,ANK2,CAMK2D,EDN1,EPAS1,GCH1,GJD3,KCNJ2,SCN4B,SPTBN4,SRI"} {"Genesets":"GO:0030261","Term":"chromosome condensation","Annotated":35,"Significant":7,"Expected":1.93,"Rank in p.value_classic":559,"p.value_elim":0.00255,"p.value_classic":0.00263,"Genes":"CDCA5,CDK1,NCAPG,NCAPG2,NCAPH,NUSAP1,TOP2A"} {"Genesets":"GO:0032735","Term":"positive regulation of interleukin-12 production","Annotated":35,"Significant":7,"Expected":1.93,"Rank in p.value_classic":560,"p.value_elim":0.00255,"p.value_classic":0.00263,"Genes":"CD40,HLA-G,IDO1,IRF1,NOD2,RIPK2,SCIMP"} {"Genesets":"GO:0002831","Term":"regulation of response to biotic stimulus","Annotated":293,"Significant":55,"Expected":16.18,"Rank in p.value_classic":40,"p.value_elim":0.00255,"p.value_classic":6.2e-16,"Genes":"ACOD1,ADAM8,AIM2,APOBEC3G,APPL2,CARD16,CCL5,CD274,CEACAM1,CFH,CLEC6A,DDX60,DTX3L,FCN1,FGL2,GBP5,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IFI35,IL12A,IL12RB1,IL15,IL27,IL4I1,IRF1,IRF7,KLRK1,LAG3,LILRA2,LYN,NCF1,NLRC5,NMI,NOD2,OPTN,PARP14,PYHIN1,RIPK2,SCIMP,SERPING1,SLAMF6,SLAMF8,SOCS1,STAT1,STAT2,TLR8,TRAFD1,TSPAN32,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0052548","Term":"regulation of endopeptidase activity","Annotated":304,"Significant":29,"Expected":16.78,"Rank in p.value_classic":563,"p.value_elim":0.00267,"p.value_classic":0.00289,"Genes":"AGT,AIM2,ATP13A2,BCL2L11,BIRC5,C3,C4A,C4B,CARD16,FAS,GRAMD4,HGF,JAK2,KLF4,LAMP3,LYN,MEFV,MMP9,NLRP12,PMAIP1,PML,PSMB8,PSMB9,PSME1,PSME2,PZP,RIPK2,SERPING1,TNFSF10"} {"Genesets":"GO:0030888","Term":"regulation of B cell proliferation","Annotated":55,"Significant":9,"Expected":3.04,"Rank in p.value_classic":566,"p.value_elim":0.00282,"p.value_classic":0.00293,"Genes":"BCL6,CD38,CD40,CD74,CTLA4,GPR183,LYN,TNFRSF21,TNFSF13B"} {"Genesets":"GO:0002548","Term":"monocyte chemotaxis","Annotated":50,"Significant":12,"Expected":2.76,"Rank in p.value_classic":263,"p.value_elim":0.00285,"p.value_classic":0.00001,"Genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CX3CR1,CXCL10,LYN,SLAMF8,TNFRSF11A,TNFSF18"} {"Genesets":"GO:0002286","Term":"T cell activation involved in immune response","Annotated":94,"Significant":22,"Expected":5.19,"Rank in p.value_classic":132,"p.value_elim":0.00289,"p.value_classic":5.6e-09,"Genes":"BCL6,CD1C,CD74,CD80,CEACAM1,FGL2,GPR183,HLA-DMB,HLA-DRA,HLA-DRB1,ICAM1,IL12RB1,IL27,JAK3,PTGER4,RELB,RIPK2,SLAMF6,SLC11A1,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0002483","Term":"antigen processing and presentation of endogenous peptide antigen","Annotated":17,"Significant":13,"Expected":0.94,"Rank in p.value_classic":51,"p.value_elim":0.00293,"p.value_classic":7.7e-14,"Genes":"B2M,ERAP2,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,TAP1,TAP2,TAPBP"} {"Genesets":"GO:0001773","Term":"myeloid dendritic cell activation","Annotated":27,"Significant":6,"Expected":1.49,"Rank in p.value_classic":567,"p.value_elim":0.00294,"p.value_classic":0.00303,"Genes":"BATF2,BATF3,RELB,SLAMF1,TSPAN32,UBD"} {"Genesets":"GO:1903975","Term":"regulation of glial cell migration","Annotated":19,"Significant":5,"Expected":1.05,"Rank in p.value_classic":570,"p.value_elim":0.003,"p.value_classic":0.00308,"Genes":"ATP1B2,CX3CR1,GPR183,P2RX4,STAP1"} {"Genesets":"GO:0006213","Term":"pyrimidine nucleoside metabolic process","Annotated":19,"Significant":5,"Expected":1.05,"Rank in p.value_classic":571,"p.value_elim":0.003,"p.value_classic":0.00308,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,TK1,TYMP"} {"Genesets":"GO:0009308","Term":"amine metabolic process","Annotated":88,"Significant":12,"Expected":4.86,"Rank in p.value_classic":585,"p.value_elim":0.00302,"p.value_classic":0.00316,"Genes":"AOC3,CYP1A1,EPAS1,GCH1,IDO1,IDO2,IL4I1,NAAA,NPR1,SAT1,SULT1C2,VCAM1"} {"Genesets":"GO:0061337","Term":"cardiac conduction","Annotated":77,"Significant":11,"Expected":4.25,"Rank in p.value_classic":593,"p.value_elim":0.00308,"p.value_classic":0.00321,"Genes":"AGT,ANK2,ATP1B2,CAMK2D,CXADR,GJD3,KCNJ2,SCN4B,SPTBN4,SRI,TRDN"} {"Genesets":"GO:0090267","Term":"positive regulation of mitotic cell cycle spindle assembly checkpoint","Annotated":12,"Significant":4,"Expected":0.66,"Rank in p.value_classic":586,"p.value_elim":0.00313,"p.value_classic":0.00319,"Genes":"AURKB,BIRC5,MAD2L1,NDC80"} {"Genesets":"GO:0002863","Term":"positive regulation of inflammatory response to antigenic stimulus","Annotated":12,"Significant":4,"Expected":0.66,"Rank in p.value_classic":587,"p.value_elim":0.00313,"p.value_classic":0.00319,"Genes":"C3,CD28,HLA-E,KARS1"} {"Genesets":"GO:0007567","Term":"parturition","Annotated":12,"Significant":4,"Expected":0.66,"Rank in p.value_classic":588,"p.value_elim":0.00313,"p.value_classic":0.00319,"Genes":"CYP1A1,EDN1,MAFF,RXFP1"} {"Genesets":"GO:0042976","Term":"activation of Janus kinase activity","Annotated":12,"Significant":4,"Expected":0.66,"Rank in p.value_classic":589,"p.value_elim":0.00313,"p.value_classic":0.00319,"Genes":"AGT,CCL5,JAK2,SOCS1"} {"Genesets":"GO:2001198","Term":"regulation of dendritic cell differentiation","Annotated":12,"Significant":4,"Expected":0.66,"Rank in p.value_classic":590,"p.value_elim":0.00313,"p.value_classic":0.00319,"Genes":"HLA-B,HLA-G,TMEM176A,TMEM176B"} {"Genesets":"GO:0002252","Term":"immune effector process","Annotated":475,"Significant":90,"Expected":26.22,"Rank in p.value_classic":18,"p.value_elim":0.00313,"p.value_classic":7.1e-26,"Genes":"APPL2,B2M,BCL6,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD1A,CD1C,CD28,CD40,CD74,CD80,CEACAM1,CFB,CFH,CR1L,CSF2RB,CX3CR1,DDX60,DLL1,DYSF,EXO1,FCN1,FGL2,GPR183,HLA-A,HLA-B,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IFI35,IL12A,IL12RB1,IL27,IL4I1,IRF7,JAK3,KARS1,KLRK1,LAG3,LILRA2,LITAF,LYN,NCF1,NMI,NOD2,P2RX7,PLPP4,PTGER4,RELB,RIPK2,RNF19B,RSAD2,S100A13,SBNO2,SCIMP,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAP1,SUCNR1,TAP2,TBX21,TLR7,TLR8,TNFSF18,ZC3H12A"} {"Genesets":"GO:0002824","Term":"positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","Annotated":99,"Significant":27,"Expected":5.47,"Rank in p.value_classic":66,"p.value_elim":0.00323,"p.value_classic":2.1e-12,"Genes":"B2M,C3,CD1A,CD1C,CD274,CD28,CD40,CLEC6A,HLA-A,HLA-B,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,JAK2,NOD2,P2RX7,RIPK2,RSAD2,SLAMF1,SLC11A1,TAP2,TBX21,TNFSF13B"} {"Genesets":"GO:0097191","Term":"extrinsic apoptotic signaling pathway","Annotated":200,"Significant":21,"Expected":11.04,"Rank in p.value_classic":599,"p.value_elim":0.00327,"p.value_classic":0.00349,"Genes":"AGT,ATF3,BCL2A1,BCL2L11,BCL2L14,BRCA1,CYLD,DEPTOR,FAS,G0S2,HGF,ICAM1,IFI27,IL12A,JAK2,KITLG,NRP1,P2RX7,PMAIP1,PML,TNFSF10"} {"Genesets":"GO:0019724","Term":"B cell mediated immunity","Annotated":114,"Significant":35,"Expected":6.29,"Rank in p.value_classic":32,"p.value_elim":0.00328,"p.value_classic":1.8e-17,"Genes":"B2M,BCL6,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD28,CD40,CD74,CR1L,CSF2RB,EXO1,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IRF7,NOD2,SERPING1,TBX21,TLR8"} {"Genesets":"GO:0031295","Term":"T cell costimulation","Annotated":37,"Significant":7,"Expected":2.04,"Rank in p.value_classic":600,"p.value_elim":0.00355,"p.value_classic":0.00366,"Genes":"CD274,CD28,CD80,KLRK1,LYN,PDCD1LG2,TNFSF13B"} {"Genesets":"GO:0032728","Term":"positive regulation of interferon-beta production","Annotated":37,"Significant":7,"Expected":2.04,"Rank in p.value_classic":601,"p.value_elim":0.00355,"p.value_classic":0.00366,"Genes":"IFIH1,IRF1,IRF7,OAS2,RIPK2,TLR7,TLR8"} {"Genesets":"GO:0002719","Term":"negative regulation of cytokine production involved in immune response","Annotated":28,"Significant":6,"Expected":1.55,"Rank in p.value_classic":604,"p.value_elim":0.00357,"p.value_classic":0.00367,"Genes":"BCL6,HLA-F,JAK3,NOD2,SLAMF1,TBX21"} {"Genesets":"GO:0001817","Term":"regulation of cytokine production","Annotated":603,"Significant":90,"Expected":33.29,"Rank in p.value_classic":25,"p.value_elim":0.00364,"p.value_classic":1.7e-18,"Genes":"ACOD1,ADAM8,AGT,AIM2,APPL2,B2M,BANK1,BCL6,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CARD16,CD274,CD28,CD40,CD74,CD80,CEACAM1,CLEC6A,CLEC9A,CX3CR1,CYLD,DLL1,FCN1,GBP1,GBP5,GBP7,GHRL,GSDMD,HGF,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IRF1,IRF7,ITK,JAK2,JAK3,KLF4,KLRK1,LAG3,LILRA2,LITAF,LRRK2,LYN,MCOLN2,MEFV,NLRP12,NMI,NOD2,OAS2,OSM,P2RX7,PDCD1LG2,PDE4B,PML,PTGER4,PYHIN1,RELB,RIPK2,RSAD2,S100A13,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOCS1,STAT1,TBX21,TLR10,TLR5,TLR7,TLR8,TNFRSF21,ZC3H12A"} {"Genesets":"GO:0002224","Term":"toll-like receptor signaling pathway","Annotated":105,"Significant":22,"Expected":5.8,"Rank in p.value_classic":157,"p.value_elim":0.0038,"p.value_classic":4.8e-08,"Genes":"ACOD1,APPL2,CD300LF,CD40,COLEC12,CTSS,GRAMD4,IFI35,IRF1,IRF7,LILRA2,LYN,NMI,NOD2,RIPK2,RSAD2,SCIMP,TICAM2,TLR10,TLR5,TLR7,TLR8"} {"Genesets":"GO:1901623","Term":"regulation of lymphocyte chemotaxis","Annotated":20,"Significant":5,"Expected":1.1,"Rank in p.value_classic":606,"p.value_elim":0.00382,"p.value_classic":0.00392,"Genes":"CCL5,CCL7,CXCL10,KLRK1,PADI2"} {"Genesets":"GO:0010529","Term":"negative regulation of transposition","Annotated":20,"Significant":5,"Expected":1.1,"Rank in p.value_classic":607,"p.value_elim":0.00382,"p.value_classic":0.00392,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,PIWIL4,TDRD9"} {"Genesets":"GO:0023061","Term":"signal release","Annotated":339,"Significant":34,"Expected":18.72,"Rank in p.value_classic":434,"p.value_elim":0.00395,"p.value_classic":0.00055,"Genes":"ADORA3,AGT,ASIC1,CCL5,CD38,CRHBP,DAB2,DTNBP1,EDN1,ERC2,EXOC3L1,GHRL,GLUL,GRIN3A,HCAR2,HLA-DRB1,IL1RN,JAK2,LRP5,LRRK2,LYN,MCTP2,OSM,P2RX4,P2RX7,PRRT2,SIDT2,SLC16A10,SRI,STX11,SUCNR1,SYT1,SYT6,TNFRSF11A"} {"Genesets":"GO:0045824","Term":"negative regulation of innate immune response","Annotated":65,"Significant":14,"Expected":3.59,"Rank in p.value_classic":254,"p.value_elim":0.00407,"p.value_classic":9.5e-06,"Genes":"ACOD1,CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,NLRC5,NMI,PARP14,SERPING1,SLAMF8,STAT2,TRAFD1"} {"Genesets":"GO:0002683","Term":"negative regulation of immune system process","Annotated":350,"Significant":58,"Expected":19.32,"Rank in p.value_classic":48,"p.value_elim":0.00416,"p.value_classic":3.2e-14,"Genes":"ACOD1,BANK1,BCL6,BTN2A2,CD274,CD300LF,CD74,CD80,CEACAM1,CR1L,CTLA4,CX3CR1,DLL1,FGL1,FGL2,GBP1,HLA-A,HLA-B,HLA-DOA,HLA-DOB,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IL31RA,IL4I1,IRF1,JAK3,KITLG,KLRK1,LAG3,LILRB3,LYN,NLRC5,NMI,NOD2,PADI2,PARP14,PDCD1,PDCD1LG2,PTGER4,SERPING1,SLAMF1,SLAMF8,SOCS1,STAP1,STAT2,TAPBPL,TBX21,TMEM176A,TMEM176B,TNFAIP6,TNFRSF21,TNFSF18,TRAFD1,TSPAN32,ZC3H12A"} {"Genesets":"GO:0016045","Term":"detection of bacterium","Annotated":13,"Significant":4,"Expected":0.72,"Rank in p.value_classic":624,"p.value_elim":0.00433,"p.value_classic":0.00441,"Genes":"HLA-A,HLA-B,HLA-DRB1,NOD2"} {"Genesets":"GO:0014821","Term":"phasic smooth muscle contraction","Annotated":13,"Significant":4,"Expected":0.72,"Rank in p.value_classic":625,"p.value_elim":0.00433,"p.value_classic":0.00441,"Genes":"EDN1,GHRL,SSTR2,TIFAB"} {"Genesets":"GO:0051231","Term":"spindle elongation","Annotated":13,"Significant":4,"Expected":0.72,"Rank in p.value_classic":626,"p.value_elim":0.00433,"p.value_classic":0.00441,"Genes":"AURKB,BIRC5,KIF11,PRC1"} {"Genesets":"GO:0001787","Term":"natural killer cell proliferation","Annotated":13,"Significant":4,"Expected":0.72,"Rank in p.value_classic":627,"p.value_elim":0.00433,"p.value_classic":0.00441,"Genes":"HLA-E,IL15,JAK2,SLAMF1"} {"Genesets":"GO:0072540","Term":"T-helper 17 cell lineage commitment","Annotated":13,"Significant":4,"Expected":0.72,"Rank in p.value_classic":628,"p.value_elim":0.00433,"p.value_classic":0.00441,"Genes":"IL12RB1,SLAMF6,TBX21,TNFSF18"} {"Genesets":"GO:0048532","Term":"anatomical structure arrangement","Annotated":13,"Significant":4,"Expected":0.72,"Rank in p.value_classic":629,"p.value_elim":0.00433,"p.value_classic":0.00441,"Genes":"DAB1,DLL1,EGR2,NRP1"} {"Genesets":"GO:0010972","Term":"negative regulation of G2/M transition of mitotic cell cycle","Annotated":59,"Significant":9,"Expected":3.26,"Rank in p.value_classic":634,"p.value_elim":0.00459,"p.value_classic":0.00476,"Genes":"AURKB,BRCA1,CDC6,CDK1,CHMP4C,CLSPN,DTL,ORC1,TICRR"} {"Genesets":"GO:0019883","Term":"antigen processing and presentation of endogenous antigen","Annotated":24,"Significant":16,"Expected":1.33,"Rank in p.value_classic":42,"p.value_elim":0.00465,"p.value_classic":3.1e-15,"Genes":"B2M,CD1A,CD1C,CD74,ERAP2,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,TAP1,TAP2,TAPBP"} {"Genesets":"GO:0051315","Term":"attachment of mitotic spindle microtubules to kinetochore","Annotated":21,"Significant":5,"Expected":1.16,"Rank in p.value_classic":638,"p.value_elim":0.0048,"p.value_classic":0.00491,"Genes":"AURKB,BIRC5,CDT1,NDC80,NUF2"} {"Genesets":"GO:0002220","Term":"innate immune response activating cell surface receptor signaling pathway","Annotated":21,"Significant":5,"Expected":1.16,"Rank in p.value_classic":639,"p.value_elim":0.0048,"p.value_classic":0.00491,"Genes":"CLEC6A,FCN1,KLRK1,LILRA2,LYN"} {"Genesets":"GO:0050798","Term":"activated T cell proliferation","Annotated":39,"Significant":7,"Expected":2.15,"Rank in p.value_classic":641,"p.value_elim":0.00482,"p.value_classic":0.00497,"Genes":"BTN2A2,BTN3A1,CD274,IL12RB1,JAK3,PDCD1LG2,SLAMF1"} {"Genesets":"GO:0000280","Term":"nuclear division","Annotated":406,"Significant":41,"Expected":22.42,"Rank in p.value_classic":351,"p.value_elim":0.00491,"p.value_classic":0.00013,"Genes":"ANLN,AURKB,BCL2L11,BIRC5,BUB1B,CCNE2,CD28,CDC6,CDCA5,CDT1,CENPK,CHMP4C,DMC1,DSCC1,EDN1,EML4,ESCO2,HORMAD1,KIF11,KIF15,KIF18B,LRP5,MAD2L1,MEIKIN,MKI67,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,PKMYT1,PRC1,RAD54B,RAD54L,SPC24,SPC25,TDRD9,TOP2A,ZWINT"} {"Genesets":"GO:0043123","Term":"positive regulation of I-kappaB kinase/NF-kappaB signaling","Annotated":181,"Significant":19,"Expected":9.99,"Rank in p.value_classic":648,"p.value_elim":0.00502,"p.value_classic":0.00532,"Genes":"APOL3,CARD16,CD40,CD74,CLEC6A,EDA,HLA-DRB1,IFIT5,LITAF,NOD2,RIPK2,S100A13,SECTM1,SLC20A1,TICAM2,TIFA,TNFSF10,TRIM22,UBD"} {"Genesets":"GO:0071353","Term":"cellular response to interleukin-4","Annotated":30,"Significant":6,"Expected":1.66,"Rank in p.value_classic":646,"p.value_elim":0.00513,"p.value_classic":0.00527,"Genes":"CD300LF,JAK3,MCM2,PARP14,PML,RUFY4"} {"Genesets":"GO:0032689","Term":"negative regulation of interferon-gamma production","Annotated":30,"Significant":6,"Expected":1.66,"Rank in p.value_classic":647,"p.value_elim":0.00513,"p.value_classic":0.00527,"Genes":"CD274,HLA-DRB1,NOD2,PDCD1LG2,SLAMF1,ZC3H12A"} {"Genesets":"GO:0051338","Term":"regulation of transferase activity","Annotated":768,"Significant":62,"Expected":42.4,"Rank in p.value_classic":510,"p.value_elim":0.00529,"p.value_classic":0.00156,"Genes":"ACSL1,ADAM8,AGT,AURKB,BUB1B,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CDC25A,CDC6,CDKN2C,CEACAM1,CISH,CLSPN,DAB1,DAB2,DEPTOR,DSCC1,DTNBP1,DTX3L,EDN1,EPHB3,FAM20A,GADD45B,GHRL,GINS2,HBEGF,HGF,HLA-DRB1,JAK2,KITLG,KLF4,LMTK2,LRP5,LRRK2,LYN,MAD2L1,MMD,MVP,NCAPG2,NCF1,NLRC5,NOD2,P2RX7,PKIB,PKMYT1,PLAAT4,PPM1E,RALB,RAPGEF2,SERINC5,SLAMF8,SLC11A1,SOCS1,STAP1,TNFAIP8L3,TNFRSF11A,VEGFC,WARS1"} {"Genesets":"GO:0043331","Term":"response to dsRNA","Annotated":40,"Significant":7,"Expected":2.21,"Rank in p.value_classic":654,"p.value_elim":0.00557,"p.value_classic":0.00574,"Genes":"COLEC12,IFIH1,NOD2,P2RX7,PMAIP1,RALB,RIPK2"} {"Genesets":"GO:0006270","Term":"DNA replication initiation","Annotated":36,"Significant":12,"Expected":1.99,"Rank in p.value_classic":172,"p.value_elim":0.00572,"p.value_classic":2.7e-07,"Genes":"CCNE2,CDC45,CDC6,CDT1,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,ORC1,TICRR"} {"Genesets":"GO:0002260","Term":"lymphocyte homeostasis","Annotated":61,"Significant":9,"Expected":3.37,"Rank in p.value_classic":665,"p.value_elim":0.00575,"p.value_classic":0.00596,"Genes":"BCL2L11,CD74,FAS,JAK3,LYN,P2RX7,PMAIP1,SIT1,TNFSF13B"} {"Genesets":"GO:0019058","Term":"viral life cycle","Annotated":282,"Significant":38,"Expected":15.57,"Rank in p.value_classic":175,"p.value_elim":0.00578,"p.value_classic":2.9e-07,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CCL8,CD28,CD74,CD80,CDK1,CHMP4C,CIITA,CXADR,DYNLT1,FCN1,GBP7,HLA-DRB1,ICAM1,IFI27,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,LAMP3,NRP1,OAS2,PARP10,RSAD2,SLAMF1,TOP2A,TPCN1,TRIM22,TRIM31,USP6NL,WWP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0070206","Term":"protein trimerization","Annotated":14,"Significant":4,"Expected":0.77,"Rank in p.value_classic":655,"p.value_elim":0.0058,"p.value_classic":0.00591,"Genes":"ASIC1,CD74,HLA-G,STEAP4"} {"Genesets":"GO:0002756","Term":"MyD88-independent toll-like receptor signaling pathway","Annotated":14,"Significant":4,"Expected":0.77,"Rank in p.value_classic":656,"p.value_elim":0.0058,"p.value_classic":0.00591,"Genes":"CD300LF,CD40,IRF7,TICAM2"} {"Genesets":"GO:0048245","Term":"eosinophil chemotaxis","Annotated":14,"Significant":4,"Expected":0.77,"Rank in p.value_classic":657,"p.value_elim":0.0058,"p.value_classic":0.00591,"Genes":"CCL13,CCL5,CCL7,CCL8"} {"Genesets":"GO:0055119","Term":"relaxation of cardiac muscle","Annotated":14,"Significant":4,"Expected":0.77,"Rank in p.value_classic":658,"p.value_elim":0.0058,"p.value_classic":0.00591,"Genes":"CAMK2D,KCNJ2,P2RX4,PDE4B"} {"Genesets":"GO:0002903","Term":"negative regulation of B cell apoptotic process","Annotated":14,"Significant":4,"Expected":0.77,"Rank in p.value_classic":659,"p.value_elim":0.0058,"p.value_classic":0.00591,"Genes":"AURKB,BCL6,CD74,PDCD1"} {"Genesets":"GO:0016553","Term":"base conversion or substitution editing","Annotated":14,"Significant":4,"Expected":0.77,"Rank in p.value_classic":660,"p.value_elim":0.0058,"p.value_classic":0.00591,"Genes":"ADARB2,APOBEC3A,APOBEC3D,APOBEC3G"} {"Genesets":"GO:0030449","Term":"regulation of complement activation","Annotated":14,"Significant":4,"Expected":0.77,"Rank in p.value_classic":661,"p.value_elim":0.0058,"p.value_classic":0.00591,"Genes":"C3,CFH,CR1L,SERPING1"} {"Genesets":"GO:1905523","Term":"positive regulation of macrophage migration","Annotated":22,"Significant":5,"Expected":1.21,"Rank in p.value_classic":668,"p.value_elim":0.00593,"p.value_classic":0.00607,"Genes":"CCL5,CX3CR1,P2RX4,SLAMF1,TNFSF18"} {"Genesets":"GO:0032740","Term":"positive regulation of interleukin-17 production","Annotated":22,"Significant":5,"Expected":1.21,"Rank in p.value_classic":669,"p.value_elim":0.00593,"p.value_classic":0.00607,"Genes":"IL15,JAK2,NOD2,OSM,SLAMF6"} {"Genesets":"GO:0046641","Term":"positive regulation of alpha-beta T cell proliferation","Annotated":22,"Significant":5,"Expected":1.21,"Rank in p.value_classic":670,"p.value_elim":0.00593,"p.value_classic":0.00607,"Genes":"CD28,HLA-A,HLA-E,JAK2,RIPK2"} {"Genesets":"GO:0043372","Term":"positive regulation of CD4-positive, alpha-beta T cell differentiation","Annotated":31,"Significant":6,"Expected":1.71,"Rank in p.value_classic":674,"p.value_elim":0.00607,"p.value_classic":0.00624,"Genes":"CD80,HLA-DRA,HLA-DRB1,IL12RB1,RIPK2,SOCS1"} {"Genesets":"GO:0034122","Term":"negative regulation of toll-like receptor signaling pathway","Annotated":31,"Significant":6,"Expected":1.71,"Rank in p.value_classic":675,"p.value_elim":0.00607,"p.value_classic":0.00624,"Genes":"ACOD1,CD300LF,GRAMD4,LILRA2,LYN,NOD2"} {"Genesets":"GO:0042554","Term":"superoxide anion generation","Annotated":31,"Significant":6,"Expected":1.71,"Rank in p.value_classic":676,"p.value_elim":0.00607,"p.value_classic":0.00624,"Genes":"AGT,EDN1,NCF1,NCF1B,NCF1C,SH3PXD2A"} {"Genesets":"GO:0045742","Term":"positive regulation of epidermal growth factor receptor signaling pathway","Annotated":31,"Significant":6,"Expected":1.71,"Rank in p.value_classic":677,"p.value_elim":0.00607,"p.value_classic":0.00624,"Genes":"AGR2,AGT,HBEGF,MMP9,NCF1,RALB"} {"Genesets":"GO:0071622","Term":"regulation of granulocyte chemotaxis","Annotated":41,"Significant":7,"Expected":2.26,"Rank in p.value_classic":683,"p.value_elim":0.00641,"p.value_classic":0.0066,"Genes":"CCL5,CD74,EDN1,NOD2,SLAMF1,TNFAIP6,TNFSF18"} {"Genesets":"GO:0050921","Term":"positive regulation of chemotaxis","Annotated":121,"Significant":14,"Expected":6.68,"Rank in p.value_classic":687,"p.value_elim":0.0065,"p.value_classic":0.00681,"Genes":"CCL5,CCL7,CD74,CX3CR1,CXCL10,EDN1,IL12A,NRP1,P2RX4,S1PR1,SLAMF1,SUCNR1,TNFSF18,VEGFC"} {"Genesets":"GO:0002237","Term":"response to molecule of bacterial origin","Annotated":278,"Significant":43,"Expected":15.35,"Rank in p.value_classic":110,"p.value_elim":0.00667,"p.value_classic":7e-10,"Genes":"ACOD1,B2M,C4B,CARD16,CCL5,CD274,CD80,CMPK2,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,EDN1,GCH1,GPR31,IDO1,IL12A,IL12RB2,IL18BP,JAK2,KLRK1,LILRA2,LITAF,LYN,NOD2,P2RX7,PDCD1LG2,PDE4B,PTGER4,RIPK2,SBNO2,SCIMP,SLC11A1,STAP1,TAP2,THBD,TICAM2,TNFRSF11A,VCAM1,ZC3H12A"} {"Genesets":"GO:0007094","Term":"mitotic spindle assembly checkpoint signaling","Annotated":44,"Significant":10,"Expected":2.43,"Rank in p.value_classic":339,"p.value_elim":0.00698,"p.value_classic":0.00011,"Genes":"AURKB,BIRC5,BUB1B,CDT1,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"Genesets":"GO:0002889","Term":"regulation of immunoglobulin mediated immune response","Annotated":52,"Significant":8,"Expected":2.87,"Rank in p.value_classic":691,"p.value_elim":0.007,"p.value_classic":0.00723,"Genes":"BCL6,C3,CD28,CD40,CR1L,HLA-E,NOD2,TBX21"} {"Genesets":"GO:0002823","Term":"negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","Annotated":45,"Significant":12,"Expected":2.48,"Rank in p.value_classic":238,"p.value_elim":0.007,"p.value_classic":3.9e-06,"Genes":"BCL6,CEACAM1,CR1L,HLA-F,HLA-G,IL4I1,JAK3,NOD2,SLAMF1,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0051281","Term":"positive regulation of release of sequestered calcium ion into cytosol","Annotated":32,"Significant":6,"Expected":1.77,"Rank in p.value_classic":694,"p.value_elim":0.00714,"p.value_classic":0.00733,"Genes":"CXCL10,CXCL11,CXCL9,F2RL3,SRI,TRDN"} {"Genesets":"GO:0010758","Term":"regulation of macrophage chemotaxis","Annotated":23,"Significant":5,"Expected":1.27,"Rank in p.value_classic":697,"p.value_elim":0.00724,"p.value_classic":0.00741,"Genes":"CCL5,SLAMF1,SLAMF8,STAP1,TNFSF18"} {"Genesets":"GO:0002675","Term":"positive regulation of acute inflammatory response","Annotated":23,"Significant":5,"Expected":1.27,"Rank in p.value_classic":698,"p.value_elim":0.00724,"p.value_classic":0.00741,"Genes":"ADAM8,C3,HLA-E,OSM,TNFRSF11A"} {"Genesets":"GO:0055074","Term":"calcium ion homeostasis","Annotated":234,"Significant":26,"Expected":12.92,"Rank in p.value_classic":431,"p.value_elim":0.00725,"p.value_classic":0.00053,"Genes":"ANK2,ANKH,ATP13A2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,FAM20A,LYN,MCOLN2,P2RX7,PML,SNX10,SRI,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0071496","Term":"cellular response to external stimulus","Annotated":284,"Significant":26,"Expected":15.68,"Rank in p.value_classic":703,"p.value_elim":0.00734,"p.value_classic":0.00787,"Genes":"AGT,ATF3,CD40,FAM107A,FAS,GLUL,GSDMD,IL15,IRF1,KCNJ2,KIF26A,LRRK2,LYN,P2RX7,PDK4,PIM1,PMAIP1,PTGER4,RALB,SESN3,TLR5,TLR7,TLR8,TNFRSF11A,VCAM1,ZC3H12A"} {"Genesets":"GO:0035456","Term":"response to interferon-beta","Annotated":29,"Significant":9,"Expected":1.6,"Rank in p.value_classic":275,"p.value_elim":0.00736,"p.value_classic":0.00002,"Genes":"ACOD1,AIM2,IFITM1,IFITM2,IFITM3,IRF1,PYHIN1,STAT1,XAF1"} {"Genesets":"GO:0002507","Term":"tolerance induction","Annotated":25,"Significant":8,"Expected":1.38,"Rank in p.value_classic":298,"p.value_elim":0.00738,"p.value_classic":0.00004,"Genes":"ACOD1,CD274,HLA-B,HLA-E,HLA-G,IDO1,LYN,PDCD1"} {"Genesets":"GO:0050671","Term":"positive regulation of lymphocyte proliferation","Annotated":121,"Significant":25,"Expected":6.68,"Rank in p.value_classic":137,"p.value_elim":0.00757,"p.value_classic":8e-09,"Genes":"BCL6,CCL5,CD274,CD28,CD38,CD40,CD74,CD80,GPR183,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-E,IL12A,IL12RB1,IL15,JAK2,JAK3,KITLG,PDCD1LG2,RIPK2,SLAMF1,TNFSF13B,VCAM1"} {"Genesets":"GO:0007249","Term":"I-kappaB kinase/NF-kappaB signaling","Annotated":269,"Significant":30,"Expected":14.85,"Rank in p.value_classic":371,"p.value_elim":0.0078,"p.value_classic":0.00019,"Genes":"APOL3,CARD16,CD40,CD74,CLEC6A,CX3CR1,EDA,EDN1,GBP7,HLA-DRB1,IFIT5,LITAF,NLRP12,NOD2,OPTN,RELB,RIPK2,S100A13,SECTM1,SLC20A1,STAT1,TICAM2,TIFA,TIFAB,TLR7,TLR8,TNFSF10,TRIM22,UBD,ZC3H12A"} {"Genesets":"GO:0001960","Term":"negative regulation of cytokine-mediated signaling pathway","Annotated":64,"Significant":9,"Expected":3.53,"Rank in p.value_classic":707,"p.value_elim":0.0079,"p.value_classic":0.00818,"Genes":"CARD16,CCL5,CYLD,IL1RN,NLRC5,PADI2,PARP14,STAP1,STAT2"} {"Genesets":"GO:0006887","Term":"exocytosis","Annotated":301,"Significant":27,"Expected":16.62,"Rank in p.value_classic":720,"p.value_elim":0.00829,"p.value_classic":0.00889,"Genes":"ATP13A2,CCL5,CCL8,CEACAM1,CRHBP,DTNBP1,ERC2,EXOC3L1,EXOC3L4,GRIN3A,HLA-F,ITSN1,LRRK2,LYN,P2RX7,PLEK,PRRT2,RALB,S100A10,S100A13,SCIN,SEPTIN4,STX11,SYNGR3,SYT1,SYT6,TNFAIP2"} {"Genesets":"GO:0045429","Term":"positive regulation of nitric oxide biosynthetic process","Annotated":33,"Significant":6,"Expected":1.82,"Rank in p.value_classic":714,"p.value_elim":0.00833,"p.value_classic":0.00855,"Genes":"AGT,EDN1,JAK2,KLF4,KLRK1,P2RX4"} {"Genesets":"GO:0071407","Term":"cellular response to organic cyclic compound","Annotated":448,"Significant":37,"Expected":24.73,"Rank in p.value_classic":728,"p.value_elim":0.00853,"p.value_classic":0.00928,"Genes":"ACOD1,BCL2L11,BRCA1,CASP7,CCL5,CCNA2,CDK1,COLEC12,CRHBP,CYP1A1,DAB2,DTNBP1,EDN1,FAM107A,GNG2,GRAMD1B,HRH2,IFIH1,IL15,JAK2,LBH,LRRK2,NCF1,NOD2,P2RX4,P2RX7,PADI2,PAQR8,PDE4B,PIM1,RALB,RAPGEF2,SSTR2,STAT1,TGM2,XRN1,ZC3H12A"} {"Genesets":"GO:0002468","Term":"dendritic cell antigen processing and presentation","Annotated":13,"Significant":6,"Expected":0.72,"Rank in p.value_classic":292,"p.value_elim":0.00862,"p.value_classic":0.00003,"Genes":"CD74,FGL2,HLA-DRA,HLA-DRB1,NOD2,SLC11A1"} {"Genesets":"GO:0072677","Term":"eosinophil migration","Annotated":17,"Significant":6,"Expected":0.94,"Rank in p.value_classic":378,"p.value_elim":0.00862,"p.value_classic":0.0002,"Genes":"ADAM8,CCL13,CCL5,CCL7,CCL8,PTGER4"} {"Genesets":"GO:0002726","Term":"positive regulation of T cell cytokine production","Annotated":24,"Significant":5,"Expected":1.33,"Rank in p.value_classic":723,"p.value_elim":0.00874,"p.value_classic":0.00895,"Genes":"B2M,HLA-A,RSAD2,SLAMF1,TBX21"} {"Genesets":"GO:1903046","Term":"meiotic cell cycle process","Annotated":151,"Significant":16,"Expected":8.34,"Rank in p.value_classic":727,"p.value_elim":0.00876,"p.value_classic":0.00921,"Genes":"BCL2L11,BUB1B,CCNE2,CDC25A,DMC1,EDN1,HORMAD1,MEIKIN,NCAPH,NDC80,NUF2,OVOL1,RAD54B,RAD54L,TDRD9,TOP2A"} {"Genesets":"GO:0032088","Term":"negative regulation of NF-kappaB transcription factor activity","Annotated":77,"Significant":10,"Expected":4.25,"Rank in p.value_classic":729,"p.value_elim":0.00918,"p.value_classic":0.00952,"Genes":"ACOD1,ADORA3,AIM2,CYLD,KLF4,NLRC5,NLRP12,NOD2,PARP10,ZC3H12A"} {"Genesets":"GO:0019730","Term":"antimicrobial humoral response","Annotated":50,"Significant":11,"Expected":2.76,"Rank in p.value_classic":320,"p.value_elim":0.00942,"p.value_classic":0.00007,"Genes":"ACOD1,CCL13,CXCL10,CXCL11,CXCL5,CXCL9,H2BC21,HLA-A,HLA-E,NOD2,SLC11A1"} {"Genesets":"GO:0006968","Term":"cellular defense response","Annotated":34,"Significant":6,"Expected":1.88,"Rank in p.value_classic":739,"p.value_elim":0.00965,"p.value_classic":0.00991,"Genes":"CX3CR1,CXCL9,HLA-G,ITK,LGALS3BP,NCF1"} {"Genesets":"GO:0042454","Term":"ribonucleoside catabolic process","Annotated":16,"Significant":4,"Expected":0.88,"Rank in p.value_classic":733,"p.value_elim":0.00965,"p.value_classic":0.00984,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,ENPP4"} {"Genesets":"GO:2000319","Term":"regulation of T-helper 17 cell differentiation","Annotated":16,"Significant":4,"Expected":0.88,"Rank in p.value_classic":734,"p.value_elim":0.00965,"p.value_classic":0.00984,"Genes":"IL12RB1,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0002830","Term":"positive regulation of type 2 immune response","Annotated":16,"Significant":4,"Expected":0.88,"Rank in p.value_classic":735,"p.value_elim":0.00965,"p.value_classic":0.00984,"Genes":"CD74,IDO1,NOD2,RSAD2"} {"Genesets":"GO:0097254","Term":"renal tubular secretion","Annotated":16,"Significant":4,"Expected":0.88,"Rank in p.value_classic":736,"p.value_elim":0.00965,"p.value_classic":0.00984,"Genes":"ABCG2,AGT,EDN1,NPR1"} {"Genesets":"GO:0046653","Term":"tetrahydrofolate metabolic process","Annotated":16,"Significant":4,"Expected":0.88,"Rank in p.value_classic":737,"p.value_elim":0.00965,"p.value_classic":0.00984,"Genes":"DHFR,GCH1,MTHFD2,TYMS"} {"Genesets":"GO:0051046","Term":"regulation of secretion","Annotated":465,"Significant":41,"Expected":25.67,"Rank in p.value_classic":530,"p.value_elim":0.00972,"p.value_classic":0.00202,"Genes":"ADAM8,ADORA3,AGT,ASIC1,ATP13A2,CCL5,CD38,CD74,CEACAM1,CRHBP,DAB2,DTNBP1,EDN1,GHRL,GLUL,GRIN3A,HCAR2,HLA-DRB1,HLA-F,IL12A,JAK2,LRP5,LRRK2,LYN,MCTP2,NPR1,OAS2,OSM,P2RX4,P2RX7,RSAD2,S100A10,SCIN,SEPTIN4,SIDT2,SRI,SYT1,SYT6,TIFAB,TNFRSF11A,VEGFC"} {"Genesets":"GO:0050778","Term":"positive regulation of immune response","Annotated":409,"Significant":83,"Expected":22.58,"Rank in p.value_classic":17,"p.value_elim":0.00974,"p.value_classic":5.3e-26,"Genes":"ACOD1,ADAM8,AIM2,APPL2,B2M,BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL5,CD1A,CD1C,CD274,CD28,CD38,CD40,CD74,CD80,CEACAM1,CFB,CFH,CLEC6A,CR1L,CTLA4,FCN1,FYB1,GBP1,GBP5,GPR31,HLA-A,HLA-B,HLA-DMB,HLA-DPB1,HLA-DQB1,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IL12A,IL12RB1,IL15,IRF7,ITK,JAK2,KARS1,KLRK1,LAG3,LILRA2,LYN,NLRC5,NMI,NOD2,P2RX7,PDE4B,PLPP4,PYHIN1,RIPK2,RSAD2,SERPING1,SLAMF1,SLAMF6,SLC11A1,STAP1,TAP2,TBX21,TLR8,TNFRSF21,TNFSF13B,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0032663","Term":"regulation of interleukin-2 production","Annotated":55,"Significant":8,"Expected":3.04,"Rank in p.value_classic":744,"p.value_elim":0.00981,"p.value_classic":0.01012,"Genes":"CD28,CD80,GBP1,LAG3,NOD2,PDE4B,RIPK2,TBX21"} {"Genesets":"GO:0002690","Term":"positive regulation of leukocyte chemotaxis","Annotated":78,"Significant":10,"Expected":4.31,"Rank in p.value_classic":751,"p.value_elim":0.01002,"p.value_classic":0.0104,"Genes":"CCL5,CCL7,CD74,CX3CR1,CXCL10,EDN1,IL12A,SLAMF1,TNFSF18,VEGFC"} {"Genesets":"GO:0019884","Term":"antigen processing and presentation of exogenous antigen","Annotated":45,"Significant":23,"Expected":2.48,"Rank in p.value_classic":28,"p.value_elim":0.01006,"p.value_classic":1.1e-17,"Genes":"B2M,CD1A,CD1C,CD74,CTSS,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,PSME1,TAP1,TAP2"} {"Genesets":"GO:0061982","Term":"meiosis I cell cycle process","Annotated":90,"Significant":11,"Expected":4.97,"Rank in p.value_classic":752,"p.value_elim":0.01009,"p.value_classic":0.01049,"Genes":"BCL2L11,CCNE2,CDC25A,DMC1,HORMAD1,MEIKIN,NDC80,RAD54B,RAD54L,TDRD9,TOP2A"} {"Genesets":"GO:0007093","Term":"mitotic cell cycle checkpoint signaling","Annotated":135,"Significant":21,"Expected":7.45,"Rank in p.value_classic":272,"p.value_elim":0.01014,"p.value_classic":0.00002,"Genes":"AURKB,BIRC5,BRCA1,BUB1B,CDC6,CDK1,CDT1,CHMP4C,CLSPN,DTL,GTSE1,MAD2L1,MUC1,NDC80,NUF2,ORC1,PML,SPC24,SPC25,TICRR,ZWINT"} {"Genesets":"GO:0042127","Term":"regulation of cell population proliferation","Annotated":1317,"Significant":115,"Expected":72.71,"Rank in p.value_classic":176,"p.value_elim":0.01014,"p.value_classic":3.1e-07,"Genes":"ADORA3,AGT,APPL2,ASCL2,ATF3,ATF5,B2M,BCL6,BIRC5,BTN2A2,CCL5,CCL8,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CEACAM1,CHRD,COMP,CSF2RB,CTLA4,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,DAB2,DLL1,E2F1,EDN1,FLT3LG,GHRL,GLUL,GPR183,HAPLN3,HBEGF,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IFI35,IFIT3,IFITM1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IQGAP3,IRF1,JAK2,JAK3,KITLG,KLF4,LBH,LRP5,LRRK2,LYN,MARCKSL1,MIR503,MMP9,MTSS1,NMI,NOD2,NPR1,NRP1,OSM,OVOL1,PARP10,PDCD1LG2,PID1,PIM1,PLAAT4,PLCD3,PML,PRC1,RAPGEF2,RIPK2,S100A13,S1PR1,SCIN,SHCBP1,SLAMF1,SOX17,SSBP3,SSTR2,STAT1,STAT2,TESC,TMEM119,TNFRSF11A,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,UHRF1,VCAM1,VEGFC,WARS1"} {"Genesets":"GO:0009612","Term":"response to mechanical stimulus","Annotated":167,"Significant":17,"Expected":9.22,"Rank in p.value_classic":753,"p.value_elim":0.01033,"p.value_classic":0.01088,"Genes":"AGT,CD40,CXCL10,EDN1,FAS,IRF1,KCNJ2,P2RX7,PKD1L3,PTGER4,STAT1,TIFAB,TLR5,TLR7,TLR8,TNFRSF11A,USP53"} {"Genesets":"GO:0002577","Term":"regulation of antigen processing and presentation","Annotated":19,"Significant":7,"Expected":1.05,"Rank in p.value_classic":301,"p.value_elim":0.01065,"p.value_classic":0.00004,"Genes":"CD74,FGL2,HLA-DOA,HLA-DOB,NOD2,SLC11A1,TAPBPL"} {"Genesets":"GO:0045088","Term":"regulation of innate immune response","Annotated":195,"Significant":38,"Expected":10.77,"Rank in p.value_classic":72,"p.value_elim":0.01076,"p.value_classic":6.7e-12,"Genes":"ACOD1,ADAM8,AIM2,APPL2,CCL5,CEACAM1,CFH,CLEC6A,FCN1,GBP5,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IFI35,IL12A,IRF1,IRF7,KLRK1,LAG3,LILRA2,LYN,NCF1,NLRC5,NMI,NOD2,PARP14,PYHIN1,SERPING1,SLAMF6,SLAMF8,SOCS1,STAT2,TLR8,TRAFD1,ZBP1,ZNFX1"} {"Genesets":"GO:0010948","Term":"negative regulation of cell cycle process","Annotated":277,"Significant":36,"Expected":15.29,"Rank in p.value_classic":222,"p.value_elim":0.01085,"p.value_classic":1.4e-06,"Genes":"ATF5,AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNF,CDC45,CDC6,CDK1,CDT1,CHMP4C,CLSPN,DTL,E2F1,E2F8,FAM107A,FBXO6,GTSE1,HLA-G,HORMAD1,KLF4,MAD2L1,MIR503,MUC1,NDC80,NUF2,ORC1,OVOL1,PML,SPC24,SPC25,TICRR,WDR76,ZWINT"} {"Genesets":"GO:0007189","Term":"adenylate cyclase-activating G protein-coupled receptor signaling pathway","Annotated":91,"Significant":11,"Expected":5.02,"Rank in p.value_classic":756,"p.value_elim":0.01093,"p.value_classic":0.01136,"Genes":"ADGRE5,ADGRG5,CXCL10,CXCL11,CXCL9,GNG2,PDE4B,PTGER4,RAPGEF2,RXFP1,S1PR1"} {"Genesets":"GO:0055067","Term":"monovalent inorganic cation homeostasis","Annotated":116,"Significant":13,"Expected":6.4,"Rank in p.value_classic":760,"p.value_elim":0.01106,"p.value_classic":0.01154,"Genes":"AGT,ATP1B2,ATP6V0D2,EDN1,KCNJ10,KCNJ2,LRRK2,NPR1,PDK4,RAB20,SLAMF8,SLC11A1,SLC12A3"} {"Genesets":"GO:0043549","Term":"regulation of kinase activity","Annotated":655,"Significant":53,"Expected":36.16,"Rank in p.value_classic":592,"p.value_elim":0.0112,"p.value_classic":0.0032,"Genes":"ACSL1,ADAM8,AGT,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CDC25A,CDC6,CDKN2C,CEACAM1,CISH,CLSPN,DAB1,DAB2,DEPTOR,DTNBP1,EDN1,EPHB3,FAM20A,GADD45B,GHRL,HBEGF,HGF,HLA-DRB1,JAK2,KITLG,LMTK2,LRP5,LRRK2,LYN,MMD,MVP,NCAPG2,NCF1,NLRC5,NOD2,P2RX7,PKIB,PKMYT1,PPM1E,RALB,RAPGEF2,SLAMF8,SLC11A1,SOCS1,STAP1,TNFAIP8L3,TNFRSF11A,VEGFC,WARS1"} {"Genesets":"GO:0015833","Term":"peptide transport","Annotated":182,"Significant":18,"Expected":10.05,"Rank in p.value_classic":762,"p.value_elim":0.01125,"p.value_classic":0.01187,"Genes":"CCL5,CD38,CD74,CRHBP,EDN1,EXOC3L1,GHRL,GLUL,HLA-DRB1,IL1RN,JAK2,LRP5,SIDT2,SLC16A10,SRI,TAP1,TAP2,TAPBP"} {"Genesets":"GO:1902106","Term":"negative regulation of leukocyte differentiation","Annotated":83,"Significant":18,"Expected":4.58,"Rank in p.value_classic":186,"p.value_elim":0.01129,"p.value_classic":4.6e-07,"Genes":"BCL6,CD74,CEACAM1,CTLA4,FGL2,HLA-G,IRF1,JAK3,LAG3,LILRB3,LYN,SOCS1,TBX21,TMEM176A,TMEM176B,TNFAIP6,TNFSF18,ZC3H12A"} {"Genesets":"GO:0001819","Term":"positive regulation of cytokine production","Annotated":396,"Significant":61,"Expected":21.86,"Rank in p.value_classic":56,"p.value_elim":0.01145,"p.value_classic":2e-13,"Genes":"ADAM8,AGT,AIM2,B2M,BRCA1,BTN3A1,BTN3A2,C3,CD274,CD28,CD40,CD74,CD80,CLEC6A,CLEC9A,FCN1,GBP5,GSDMD,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IRF1,IRF7,ITK,JAK2,KLRK1,LILRA2,LRRK2,MCOLN2,MEFV,NLRP12,NOD2,OAS2,OSM,P2RX7,PDE4B,PTGER4,PYHIN1,RIPK2,RSAD2,S100A13,SCIMP,SLAMF1,SLAMF6,SLC11A1,STAT1,TBX21,TLR5,TLR7,TLR8"} {"Genesets":"GO:0042886","Term":"amide transport","Annotated":210,"Significant":20,"Expected":11.59,"Rank in p.value_classic":768,"p.value_elim":0.01162,"p.value_classic":0.01229,"Genes":"ABCB1,ABCG2,CCL5,CD38,CD74,CRHBP,EDN1,EXOC3L1,GHRL,GLUL,HLA-DRB1,IL1RN,JAK2,LRP5,SIDT2,SLC16A10,SRI,TAP1,TAP2,TAPBP"} {"Genesets":"GO:0071260","Term":"cellular response to mechanical stimulus","Annotated":68,"Significant":9,"Expected":3.75,"Rank in p.value_classic":763,"p.value_elim":0.01165,"p.value_classic":0.01205,"Genes":"AGT,CD40,FAS,IRF1,KCNJ2,PTGER4,TLR5,TLR7,TLR8"} {"Genesets":"GO:0002682","Term":"regulation of immune system process","Annotated":1153,"Significant":156,"Expected":63.66,"Rank in p.value_classic":13,"p.value_elim":0.01179,"p.value_classic":1.8e-27,"Genes":"ACOD1,ADAM8,AIM2,APPL2,B2M,BANK1,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL5,CCL7,CCL8,CD101,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD74,CD80,CEACAM1,CFB,CFH,CLEC6A,COLEC12,CR1L,CTLA4,CTSS,CX3CR1,CXCL10,CXCR3,CYLD,DDX60,DLL1,EDN1,FAXDC2,FCN1,FGL1,FGL2,FYB1,GBP1,GBP5,GPR183,GPR31,GRAMD4,HCAR2,HLA-A,HLA-B,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IFI35,IFIH1,IL12A,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IRF1,IRF7,ITK,JAK2,JAK3,KARS1,KITLG,KLRK1,LAG3,LILRA2,LILRB3,LITAF,LRRK2,LYN,LYVE1,MEFV,NCF1,NLRC5,NMI,NOD2,P2RX4,P2RX7,PADI2,PARP14,PDCD1,PDCD1LG2,PDE4B,PLPP4,PTGER4,PYHIN1,RIPK2,RSAD2,SCIMP,SCIN,SERPING1,SIT1,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SOCS1,STAP1,STAT1,STAT2,TAL1,TAP2,TAPBP,TAPBPL,TBX21,TESC,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TMEM176A,TMEM176B,TNFAIP6,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TRAFD1,TSPAN32,VCAM1,VEGFC,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0071887","Term":"leukocyte apoptotic process","Annotated":106,"Significant":20,"Expected":5.85,"Rank in p.value_classic":217,"p.value_elim":0.01195,"p.value_classic":1.2e-06,"Genes":"ADAM8,AURKB,BCL2L11,BCL6,CCL5,CD274,CD74,FAS,GIMAP8,HCAR2,IDO1,IRF7,JAK3,KITLG,LYN,NOD2,P2RX7,PDCD1,RAPGEF2,TNFRSF21"} {"Genesets":"GO:2001238","Term":"positive regulation of extrinsic apoptotic signaling pathway","Annotated":46,"Significant":7,"Expected":2.54,"Rank in p.value_classic":773,"p.value_elim":0.01205,"p.value_classic":0.0124,"Genes":"AGT,ATF3,CYLD,G0S2,PMAIP1,PML,TNFSF10"} {"Genesets":"GO:0034134","Term":"toll-like receptor 2 signaling pathway","Annotated":17,"Significant":4,"Expected":0.94,"Rank in p.value_classic":769,"p.value_elim":0.01209,"p.value_classic":0.01232,"Genes":"ACOD1,LYN,NOD2,RIPK2"} {"Genesets":"GO:0090026","Term":"positive regulation of monocyte chemotaxis","Annotated":17,"Significant":4,"Expected":0.94,"Rank in p.value_classic":770,"p.value_elim":0.01209,"p.value_classic":0.01232,"Genes":"CCL5,CX3CR1,CXCL10,TNFSF18"} {"Genesets":"GO:2000107","Term":"negative regulation of leukocyte apoptotic process","Annotated":50,"Significant":10,"Expected":2.76,"Rank in p.value_classic":410,"p.value_elim":0.01248,"p.value_classic":0.00034,"Genes":"AURKB,BCL6,CCL5,CD74,IDO1,IRF7,JAK3,KITLG,NOD2,PDCD1"} {"Genesets":"GO:2000106","Term":"regulation of leukocyte apoptotic process","Annotated":83,"Significant":18,"Expected":4.58,"Rank in p.value_classic":187,"p.value_elim":0.0125,"p.value_classic":4.6e-07,"Genes":"ADAM8,AURKB,BCL2L11,BCL6,CCL5,CD274,CD74,GIMAP8,HCAR2,IDO1,IRF7,JAK3,KITLG,LYN,NOD2,P2RX7,PDCD1,RAPGEF2"} {"Genesets":"GO:0043029","Term":"T cell homeostasis","Annotated":36,"Significant":6,"Expected":1.99,"Rank in p.value_classic":777,"p.value_elim":0.01274,"p.value_classic":0.01307,"Genes":"BCL2L11,FAS,JAK3,P2RX7,PMAIP1,SIT1"} {"Genesets":"GO:0046006","Term":"regulation of activated T cell proliferation","Annotated":36,"Significant":6,"Expected":1.99,"Rank in p.value_classic":778,"p.value_elim":0.01274,"p.value_classic":0.01307,"Genes":"BTN2A2,CD274,IL12RB1,JAK3,PDCD1LG2,SLAMF1"} {"Genesets":"GO:0002714","Term":"positive regulation of B cell mediated immunity","Annotated":36,"Significant":6,"Expected":1.99,"Rank in p.value_classic":779,"p.value_elim":0.01274,"p.value_classic":0.01307,"Genes":"C3,CD28,CD40,HLA-E,NOD2,TBX21"} {"Genesets":"GO:0002891","Term":"positive regulation of immunoglobulin mediated immune response","Annotated":36,"Significant":6,"Expected":1.99,"Rank in p.value_classic":780,"p.value_elim":0.01274,"p.value_classic":0.01307,"Genes":"C3,CD28,CD40,HLA-E,NOD2,TBX21"} {"Genesets":"GO:1903670","Term":"regulation of sprouting angiogenesis","Annotated":36,"Significant":6,"Expected":1.99,"Rank in p.value_classic":781,"p.value_elim":0.01274,"p.value_classic":0.01307,"Genes":"CEACAM1,DLL1,E2F2,GHRL,GLUL,KLF4"} {"Genesets":"GO:0016064","Term":"immunoglobulin mediated immune response","Annotated":112,"Significant":34,"Expected":6.18,"Rank in p.value_classic":35,"p.value_elim":0.01318,"p.value_classic":7.8e-17,"Genes":"B2M,BCL6,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD28,CD40,CD74,CR1L,CSF2RB,EXO1,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,IRF7,NOD2,SERPING1,TBX21,TLR8"} {"Genesets":"GO:0031341","Term":"regulation of cell killing","Annotated":74,"Significant":23,"Expected":4.09,"Rank in p.value_classic":67,"p.value_elim":0.01329,"p.value_classic":4.7e-12,"Genes":"B2M,CD1A,CD1C,CEACAM1,CFH,CR1L,CX3CR1,HLA-A,HLA-B,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,KLRK1,LAG3,P2RX7,SLAMF6,STAP1,TAP2"} {"Genesets":"GO:0071466","Term":"cellular response to xenobiotic stimulus","Annotated":119,"Significant":13,"Expected":6.57,"Rank in p.value_classic":790,"p.value_elim":0.01352,"p.value_classic":0.01411,"Genes":"ABCB1,ACSL1,AIM2,APOBEC3A,CBR3,CD69,CRHBP,CYP1A1,E2F1,EDN1,MCM7,PDE4B,PPM1E"} {"Genesets":"GO:0002697","Term":"regulation of immune effector process","Annotated":296,"Significant":51,"Expected":16.34,"Rank in p.value_classic":58,"p.value_elim":0.0138,"p.value_classic":2.5e-13,"Genes":"APPL2,B2M,BCL6,C3,CD1A,CD1C,CD28,CD40,CD74,CD80,CEACAM1,CFH,CR1L,CX3CR1,DDX60,FCN1,FGL2,HLA-A,HLA-B,HLA-DMB,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL27,IL4I1,JAK3,KLRK1,LAG3,LITAF,LYN,NCF1,NOD2,P2RX7,RIPK2,RSAD2,SCIMP,SERPING1,SLAMF1,SLAMF6,SLAMF8,STAP1,TAP2,TBX21,TLR7,TNFSF18,ZC3H12A"} {"Genesets":"GO:0044093","Term":"positive regulation of molecular function","Annotated":1327,"Significant":94,"Expected":73.26,"Rank in p.value_classic":679,"p.value_elim":0.01385,"p.value_classic":0.00635,"Genes":"ABCB1,ACSL1,ADAM8,ADORA3,AGT,AIM2,ANK2,ANTXR1,ARAP2,ATP1B2,AURKB,B2M,BCL2L11,CARD16,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,CDC6,CDT1,CLSPN,CTSS,CX3CR1,DAB1,DHFR,DSCC1,DTX3L,EDA,EDN1,EPHB3,FAM20A,FAS,GCH1,GHRL,GINS2,GRAMD4,HBEGF,HLA-DRB1,ITK,JAK2,KITLG,KLF4,LMTK2,LRP5,LRRK2,LYN,MEFV,MMD,MMP9,NCF1,NLRP12,NOD2,NRP1,P2RX7,PKIB,PLAAT4,PLEK,PMAIP1,PML,PSME1,PSME2,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RHEBL1,RIPK2,RSU1,RXFP1,S100A10,S1PR1,SERINC5,SLC11A1,SOCS1,STAP1,STMN1,SYNGR3,TESC,TGM2,TNFAIP8L3,TNFRSF11A,TNFSF10,TNFSF18,TRDN,TRIM22,TRIM31,UHRF1,USP6NL,VEGFC"} {"Genesets":"GO:0048678","Term":"response to axon injury","Annotated":70,"Significant":9,"Expected":3.86,"Rank in p.value_classic":793,"p.value_elim":0.01396,"p.value_classic":0.01443,"Genes":"CDK1,DHFR,JAK2,KLF4,KREMEN1,LYN,P2RX4,RTN4RL1,SCARF1"} {"Genesets":"GO:0044774","Term":"mitotic DNA integrity checkpoint signaling","Annotated":82,"Significant":10,"Expected":4.53,"Rank in p.value_classic":796,"p.value_elim":0.01403,"p.value_classic":0.01454,"Genes":"BRCA1,CDC6,CDK1,CLSPN,DTL,GTSE1,MUC1,ORC1,PML,TICRR"} {"Genesets":"GO:0002253","Term":"activation of immune response","Annotated":245,"Significant":45,"Expected":13.53,"Rank in p.value_classic":61,"p.value_elim":0.01427,"p.value_classic":6.7e-13,"Genes":"AIM2,APPL2,BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD28,CD38,CEACAM1,CFB,CFH,CLEC6A,CR1L,CTLA4,FCN1,FYB1,GBP1,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,ITK,KLRK1,LILRA2,LYN,NOD2,PDE4B,PLPP4,PYHIN1,RIPK2,SERPING1,STAP1,TNFRSF21,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0055078","Term":"sodium ion homeostasis","Annotated":27,"Significant":5,"Expected":1.49,"Rank in p.value_classic":797,"p.value_elim":0.0145,"p.value_classic":0.01483,"Genes":"AGT,ATP1B2,EDN1,NPR1,SLC12A3"} {"Genesets":"GO:0007435","Term":"salivary gland morphogenesis","Annotated":27,"Significant":5,"Expected":1.49,"Rank in p.value_classic":798,"p.value_elim":0.0145,"p.value_classic":0.01483,"Genes":"EDA,HGF,NRP1,POLB,TGM2"} {"Genesets":"GO:0035590","Term":"purinergic nucleotide receptor signaling pathway","Annotated":27,"Significant":5,"Expected":1.49,"Rank in p.value_classic":799,"p.value_elim":0.0145,"p.value_classic":0.01483,"Genes":"ADORA3,NECAB2,P2RX4,P2RX7,P2RY14"} {"Genesets":"GO:0030890","Term":"positive regulation of B cell proliferation","Annotated":37,"Significant":6,"Expected":2.04,"Rank in p.value_classic":800,"p.value_elim":0.01452,"p.value_classic":0.0149,"Genes":"BCL6,CD38,CD40,CD74,GPR183,TNFSF13B"} {"Genesets":"GO:0001906","Term":"cell killing","Annotated":119,"Significant":27,"Expected":6.57,"Rank in p.value_classic":108,"p.value_elim":0.01457,"p.value_classic":2.2e-10,"Genes":"B2M,C3,CCL13,CD1A,CD1C,CEACAM1,CFH,CR1L,CX3CR1,HLA-A,HLA-B,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,KLRK1,LAG3,P2RX7,RNF19B,SLAMF6,SLAMF7,STAP1,TAP2"} {"Genesets":"GO:0006875","Term":"cellular metal ion homeostasis","Annotated":320,"Significant":31,"Expected":17.67,"Rank in p.value_classic":513,"p.value_elim":0.01476,"p.value_classic":0.00166,"Genes":"AGT,ANK2,ATP13A2,ATP1B2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNJ2,LYN,MCOLN2,MT2A,P2RX7,PML,SCO2,SLC11A1,SLC31A2,SRI,STEAP4,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0039530","Term":"MDA-5 signaling pathway","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":801,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"DDX60,IFIH1,IRF7"} {"Genesets":"GO:0002291","Term":"T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":802,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"FGL2,HLA-DMB,ICAM1"} {"Genesets":"GO:0051256","Term":"mitotic spindle midzone assembly","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":803,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"AURKB,BIRC5,PRC1"} {"Genesets":"GO:0002836","Term":"positive regulation of response to tumor cell","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":804,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"CD274,HLA-DRB1,IL12A"} {"Genesets":"GO:0002839","Term":"positive regulation of immune response to tumor cell","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":805,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"CD274,HLA-DRB1,IL12A"} {"Genesets":"GO:0032817","Term":"regulation of natural killer cell proliferation","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":806,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"HLA-E,IL15,JAK2"} {"Genesets":"GO:0070099","Term":"regulation of chemokine-mediated signaling pathway","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":807,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"CCL5,EDN1,PADI2"} {"Genesets":"GO:0035457","Term":"cellular response to interferon-alpha","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":808,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"IFIT2,IFIT3,PYHIN1"} {"Genesets":"GO:0031665","Term":"negative regulation of lipopolysaccharide-mediated signaling pathway","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":809,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"ACOD1,CARD16,LILRA2"} {"Genesets":"GO:0060397","Term":"growth hormone receptor signaling pathway via JAK-STAT","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":810,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"JAK2,JAK3,LYN"} {"Genesets":"GO:0006568","Term":"tryptophan metabolic process","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":811,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"IDO1,IDO2,IL4I1"} {"Genesets":"GO:0006586","Term":"indolalkylamine metabolic process","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":812,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"IDO1,IDO2,IL4I1"} {"Genesets":"GO:0045654","Term":"positive regulation of megakaryocyte differentiation","Annotated":10,"Significant":3,"Expected":0.55,"Rank in p.value_classic":813,"p.value_elim":0.01479,"p.value_classic":0.01502,"Genes":"FAXDC2,SCIN,TESC"} {"Genesets":"GO:0007076","Term":"mitotic chromosome condensation","Annotated":18,"Significant":4,"Expected":0.99,"Rank in p.value_classic":814,"p.value_elim":0.01488,"p.value_classic":0.01516,"Genes":"CDCA5,NCAPG,NCAPH,NUSAP1"} {"Genesets":"GO:0034104","Term":"negative regulation of tissue remodeling","Annotated":18,"Significant":4,"Expected":0.99,"Rank in p.value_classic":815,"p.value_elim":0.01488,"p.value_classic":0.01516,"Genes":"AGT,CD38,P2RX7,TMEM119"} {"Genesets":"GO:1903083","Term":"protein localization to condensed chromosome","Annotated":18,"Significant":4,"Expected":0.99,"Rank in p.value_classic":816,"p.value_elim":0.01488,"p.value_classic":0.01516,"Genes":"AURKB,CDK1,CDT1,NDC80"} {"Genesets":"GO:0045091","Term":"regulation of single stranded viral RNA replication via double stranded DNA intermediate","Annotated":18,"Significant":4,"Expected":0.99,"Rank in p.value_classic":817,"p.value_elim":0.01488,"p.value_classic":0.01516,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,TOP2A"} {"Genesets":"GO:1902074","Term":"response to salt","Annotated":18,"Significant":4,"Expected":0.99,"Rank in p.value_classic":818,"p.value_elim":0.01488,"p.value_classic":0.01516,"Genes":"ANKH,DAB2,EDN1,ZC3H12A"} {"Genesets":"GO:0034501","Term":"protein localization to kinetochore","Annotated":18,"Significant":4,"Expected":0.99,"Rank in p.value_classic":819,"p.value_elim":0.01488,"p.value_classic":0.01516,"Genes":"AURKB,CDK1,CDT1,NDC80"} {"Genesets":"GO:0008285","Term":"negative regulation of cell population proliferation","Annotated":570,"Significant":51,"Expected":31.47,"Rank in p.value_classic":420,"p.value_elim":0.01494,"p.value_classic":0.00043,"Genes":"ADORA3,APPL2,ASCL2,ATF5,B2M,BCL6,BTN2A2,CCL8,CD274,CD80,CDC6,CDH5,CDKN2C,CEACAM1,CTLA4,CXADR,DAB2,DLL1,E2F1,GHRL,HLA-DRB1,HLA-G,IDO1,IFI35,IFIT3,IFITM1,IL12A,IL15,IL4I1,IRF1,JAK2,KLF4,LYN,MIR503,MTSS1,NMI,NPR1,OSM,OVOL1,PARP10,PDCD1LG2,PLAAT4,PML,RAPGEF2,SCIN,SSTR2,STAT1,TESC,TNFRSF21,TSPAN32,WARS1"} {"Genesets":"GO:0086065","Term":"cell communication involved in cardiac conduction","Annotated":48,"Significant":7,"Expected":2.65,"Rank in p.value_classic":822,"p.value_elim":0.01508,"p.value_classic":0.01551,"Genes":"ANK2,ATP1B2,CAMK2D,CXADR,SCN4B,SRI,TRDN"} {"Genesets":"GO:0044818","Term":"mitotic G2/M transition checkpoint","Annotated":48,"Significant":7,"Expected":2.65,"Rank in p.value_classic":823,"p.value_elim":0.01508,"p.value_classic":0.01551,"Genes":"BRCA1,CDC6,CDK1,CLSPN,DTL,ORC1,TICRR"} {"Genesets":"GO:0046718","Term":"viral entry into host cell","Annotated":127,"Significant":18,"Expected":7.01,"Rank in p.value_classic":381,"p.value_elim":0.0155,"p.value_classic":0.00021,"Genes":"CD74,CD80,CDK1,CIITA,CXADR,DYNLT1,FCN1,HLA-DRB1,ICAM1,IFITM1,IFITM2,IFITM3,NRP1,SLAMF1,TPCN1,TRIM22,TRIM31,WWP1"} {"Genesets":"GO:0043085","Term":"positive regulation of catalytic activity","Annotated":988,"Significant":73,"Expected":54.55,"Rank in p.value_classic":667,"p.value_elim":0.01552,"p.value_classic":0.00604,"Genes":"ACSL1,ADAM8,ADORA3,AGT,AIM2,ANTXR1,ARAP2,AURKB,BCL2L11,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,CDC6,CLSPN,DAB1,DHFR,DSCC1,DTX3L,EDN1,EPHB3,FAM20A,FAS,GCH1,GHRL,GINS2,GRAMD4,HBEGF,HLA-DRB1,ITK,JAK2,KITLG,KLF4,LMTK2,LRRK2,LYN,MEFV,MMD,NCF1,NLRP12,NOD2,P2RX7,PKIB,PLAAT4,PLEK,PMAIP1,PML,PSME1,PSME2,RALB,RAPGEF2,RASGEF1C,RASGRF1,RIPK2,RSU1,RXFP1,S100A10,S1PR1,SERINC5,SLC11A1,SOCS1,STAP1,TGM2,TNFAIP8L3,TNFRSF11A,TNFSF10,UHRF1,USP6NL,VEGFC"} {"Genesets":"GO:0044403","Term":"biological process involved in symbiotic interaction","Annotated":250,"Significant":27,"Expected":13.8,"Rank in p.value_classic":444,"p.value_elim":0.01566,"p.value_classic":0.00065,"Genes":"APOL1,CCL5,CCL8,CD74,CD80,CDK1,CHMP4C,CIITA,CX3CR1,CXADR,DYNLT1,FCN1,HLA-DRB1,ICAM1,IFI27,IFITM1,IFITM2,IFITM3,IGF2R,JAK2,NRP1,SLAMF1,TPCN1,TRIM22,TRIM31,WWP1,ZC3H12A"} {"Genesets":"GO:0042093","Term":"T-helper cell differentiation","Annotated":61,"Significant":15,"Expected":3.37,"Rank in p.value_classic":200,"p.value_elim":0.01613,"p.value_classic":7.6e-07,"Genes":"BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:1903047","Term":"mitotic cell cycle process","Annotated":716,"Significant":67,"Expected":39.53,"Rank in p.value_classic":268,"p.value_elim":0.01614,"p.value_classic":0.00001,"Genes":"ABCB1,ANLN,APPL2,AURKB,BACH1,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CENPK,CHMP4C,CLSPN,CYP1A1,DSCC1,DTL,DYNLT1,E2F1,EDN1,EML4,ESCO2,FAM107A,GTSE1,IQGAP3,KIF11,KIF15,KIF18B,KLF4,LRP5,MAD2L1,MCM2,MCM4,MCM6,MKI67,MUC1,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,ORC1,PKMYT1,PML,PRC1,PSME1,PSME2,RRM2,SPC24,SPC25,STMN1,TACC2,TICRR,UBD,ZWINT"} {"Genesets":"GO:0002396","Term":"MHC protein complex assembly","Annotated":17,"Significant":15,"Expected":0.94,"Rank in p.value_classic":30,"p.value_elim":0.01622,"p.value_classic":1.4e-17,"Genes":"B2M,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,TAPBP,TAPBPL"} {"Genesets":"GO:0002501","Term":"peptide antigen assembly with MHC protein complex","Annotated":17,"Significant":15,"Expected":0.94,"Rank in p.value_classic":31,"p.value_elim":0.01622,"p.value_classic":1.4e-17,"Genes":"B2M,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,TAPBP,TAPBPL"} {"Genesets":"GO:0009615","Term":"response to virus","Annotated":347,"Significant":55,"Expected":19.16,"Rank in p.value_classic":64,"p.value_elim":0.01671,"p.value_classic":9.9e-13,"Genes":"ACOD1,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,BATF3,CCL5,CCL8,CD40,CXCL10,CXCL9,CYP1A1,DDX60,DTX3L,FGL2,GBP1,GBP3,GBP7,IFI27,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL15,IL27,IRF1,IRF7,ISG20,JAK2,NLRC5,NMI,OAS2,PMAIP1,PML,RSAD2,RTP4,SERINC5,STAT1,STAT2,STMN1,TBX21,TLR7,TLR8,TRIM22,TSPAN32,VWCE,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0000070","Term":"mitotic sister chromatid segregation","Annotated":194,"Significant":24,"Expected":10.71,"Rank in p.value_classic":368,"p.value_elim":0.01695,"p.value_classic":0.00017,"Genes":"AURKB,BIRC5,BUB1B,CDC6,CDCA5,CDT1,CENPK,CHMP4C,DSCC1,EML4,ESCO2,KIF11,KIF18B,MAD2L1,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,PRC1,SPC24,SPC25,ZWINT"} {"Genesets":"GO:0140014","Term":"mitotic nuclear division","Annotated":306,"Significant":32,"Expected":16.89,"Rank in p.value_classic":415,"p.value_elim":0.01707,"p.value_classic":0.00038,"Genes":"ANLN,AURKB,BIRC5,BUB1B,CD28,CDC6,CDCA5,CDT1,CENPK,CHMP4C,DSCC1,EDN1,EML4,ESCO2,KIF11,KIF15,KIF18B,LRP5,MAD2L1,MKI67,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,PKMYT1,PRC1,SPC24,SPC25,ZWINT"} {"Genesets":"GO:0030003","Term":"cellular cation homeostasis","Annotated":383,"Significant":35,"Expected":21.15,"Rank in p.value_classic":545,"p.value_elim":0.01708,"p.value_classic":0.00234,"Genes":"AGT,ANK2,ATP13A2,ATP1B2,ATP6V0D2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNJ2,LRRK2,LYN,MCOLN2,MT2A,P2RX7,PML,RAB20,SCO2,SLAMF8,SLC11A1,SLC31A2,SRI,STEAP4,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0098586","Term":"cellular response to virus","Annotated":85,"Significant":10,"Expected":4.69,"Rank in p.value_classic":835,"p.value_elim":0.01773,"p.value_classic":0.01836,"Genes":"CCL5,CXCL10,DDX60,IFIH1,IL12A,IRF7,JAK2,TLR7,VWCE,ZC3H12A"} {"Genesets":"GO:0050871","Term":"positive regulation of B cell activation","Annotated":73,"Significant":9,"Expected":4.03,"Rank in p.value_classic":841,"p.value_elim":0.01803,"p.value_classic":0.01863,"Genes":"BCL6,CD28,CD38,CD40,CD74,GPR183,NOD2,TBX21,TNFSF13B"} {"Genesets":"GO:0043011","Term":"myeloid dendritic cell differentiation","Annotated":19,"Significant":4,"Expected":1.05,"Rank in p.value_classic":836,"p.value_elim":0.01804,"p.value_classic":0.01838,"Genes":"BATF2,BATF3,RELB,UBD"} {"Genesets":"GO:0010818","Term":"T cell chemotaxis","Annotated":19,"Significant":4,"Expected":1.05,"Rank in p.value_classic":837,"p.value_elim":0.01804,"p.value_classic":0.01838,"Genes":"CCL5,CXCL10,CXCL11,GPR183"} {"Genesets":"GO:0039692","Term":"single stranded viral RNA replication via double stranded DNA intermediate","Annotated":19,"Significant":4,"Expected":1.05,"Rank in p.value_classic":838,"p.value_elim":0.01804,"p.value_classic":0.01838,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,TOP2A"} {"Genesets":"GO:0032715","Term":"negative regulation of interleukin-6 production","Annotated":39,"Significant":6,"Expected":2.15,"Rank in p.value_classic":844,"p.value_elim":0.01859,"p.value_classic":0.01905,"Genes":"BANK1,GHRL,HGF,NLRP12,SLAMF1,ZC3H12A"} {"Genesets":"GO:0046879","Term":"hormone secretion","Annotated":206,"Significant":19,"Expected":11.37,"Rank in p.value_classic":849,"p.value_elim":0.01862,"p.value_classic":0.01961,"Genes":"AGT,CCL5,CD38,CRHBP,DAB2,EDN1,EXOC3L1,GHRL,GLUL,HCAR2,HLA-DRB1,IL1RN,JAK2,LRP5,LYN,OSM,SIDT2,SLC16A10,SRI"} {"Genesets":"GO:0031102","Term":"neuron projection regeneration","Annotated":50,"Significant":7,"Expected":2.76,"Rank in p.value_classic":845,"p.value_elim":0.01863,"p.value_classic":0.01915,"Genes":"DHFR,HGF,JAK2,KLF4,KREMEN1,RTN4RL1,SCARF1"} {"Genesets":"GO:0032757","Term":"positive regulation of interleukin-8 production","Annotated":50,"Significant":7,"Expected":2.76,"Rank in p.value_classic":846,"p.value_elim":0.01863,"p.value_classic":0.01915,"Genes":"CD74,FCN1,LILRA2,NOD2,TLR5,TLR7,TLR8"} {"Genesets":"GO:0002293","Term":"alpha-beta T cell differentiation involved in immune response","Annotated":62,"Significant":15,"Expected":3.42,"Rank in p.value_classic":211,"p.value_elim":0.01864,"p.value_classic":9.5e-07,"Genes":"BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0002294","Term":"CD4-positive, alpha-beta T cell differentiation involved in immune response","Annotated":62,"Significant":15,"Expected":3.42,"Rank in p.value_classic":212,"p.value_elim":0.01864,"p.value_classic":9.5e-07,"Genes":"BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0002287","Term":"alpha-beta T cell activation involved in immune response","Annotated":62,"Significant":15,"Expected":3.42,"Rank in p.value_classic":213,"p.value_elim":0.01864,"p.value_classic":9.5e-07,"Genes":"BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0007127","Term":"meiosis I","Annotated":86,"Significant":10,"Expected":4.75,"Rank in p.value_classic":850,"p.value_elim":0.01911,"p.value_classic":0.01979,"Genes":"BCL2L11,CCNE2,DMC1,HORMAD1,MEIKIN,NDC80,RAD54B,RAD54L,TDRD9,TOP2A"} {"Genesets":"GO:0097028","Term":"dendritic cell differentiation","Annotated":41,"Significant":9,"Expected":2.26,"Rank in p.value_classic":409,"p.value_elim":0.01915,"p.value_classic":0.00032,"Genes":"BATF2,BATF3,HLA-B,HLA-G,LYN,RELB,TMEM176A,TMEM176B,UBD"} {"Genesets":"GO:0046632","Term":"alpha-beta T cell differentiation","Annotated":100,"Significant":20,"Expected":5.52,"Rank in p.value_classic":185,"p.value_elim":0.01918,"p.value_classic":4.4e-07,"Genes":"BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF1,ITK,JAK3,PTGER4,RELB,RIPK2,RSAD2,SLAMF6,SOCS1,TBX21,TNFSF18,TNFSF8,ZC3H12A"} {"Genesets":"GO:1903707","Term":"negative regulation of hemopoiesis","Annotated":88,"Significant":18,"Expected":4.86,"Rank in p.value_classic":218,"p.value_elim":0.01936,"p.value_classic":1.2e-06,"Genes":"BCL6,CD74,CEACAM1,CTLA4,FGL2,HLA-G,IRF1,JAK3,LAG3,LILRB3,LYN,SOCS1,TBX21,TMEM176A,TMEM176B,TNFAIP6,TNFSF18,ZC3H12A"} {"Genesets":"GO:0086004","Term":"regulation of cardiac muscle cell contraction","Annotated":29,"Significant":5,"Expected":1.6,"Rank in p.value_classic":866,"p.value_elim":0.0195,"p.value_classic":0.01993,"Genes":"ANK2,CAMK2D,KCNJ2,PDE4B,SRI"} {"Genesets":"GO:0007431","Term":"salivary gland development","Annotated":29,"Significant":5,"Expected":1.6,"Rank in p.value_classic":867,"p.value_elim":0.0195,"p.value_classic":0.01993,"Genes":"EDA,HGF,NRP1,POLB,TGM2"} {"Genesets":"GO:0071677","Term":"positive regulation of mononuclear cell migration","Annotated":62,"Significant":8,"Expected":3.42,"Rank in p.value_classic":869,"p.value_elim":0.01951,"p.value_classic":0.0201,"Genes":"ADAM8,CCL5,CCL7,CX3CR1,CXCL10,IL12A,SLAMF1,TNFSF18"} {"Genesets":"GO:0034154","Term":"toll-like receptor 7 signaling pathway","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":852,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"RSAD2,SCIMP,TLR7"} {"Genesets":"GO:0010522","Term":"regulation of calcium ion transport into cytosol","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":853,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"P2RX4,P2RX7,PML"} {"Genesets":"GO:0046007","Term":"negative regulation of activated T cell proliferation","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":854,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"BTN2A2,CD274,PDCD1LG2"} {"Genesets":"GO:0048302","Term":"regulation of isotype switching to IgG isotypes","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":855,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"CD28,CD40,TBX21"} {"Genesets":"GO:0002664","Term":"regulation of T cell tolerance induction","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":856,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"HLA-B,HLA-G,IDO1"} {"Genesets":"GO:0098883","Term":"synapse pruning","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":857,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"C1QB,C3,CX3CR1"} {"Genesets":"GO:0046135","Term":"pyrimidine nucleoside catabolic process","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":858,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G"} {"Genesets":"GO:0000022","Term":"mitotic spindle elongation","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":859,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"AURKB,BIRC5,PRC1"} {"Genesets":"GO:0001696","Term":"gastric acid secretion","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":860,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"GHRL,HRH2,SNX10"} {"Genesets":"GO:0021535","Term":"cell migration in hindbrain","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":861,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"ATP1B2,DAB1,PLXNA2"} {"Genesets":"GO:0060330","Term":"regulation of response to interferon-gamma","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":862,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"NLRC5,PARP14,SOCS1"} {"Genesets":"GO:0060334","Term":"regulation of interferon-gamma-mediated signaling pathway","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":863,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"NLRC5,PARP14,SOCS1"} {"Genesets":"GO:0035813","Term":"regulation of renal sodium excretion","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":864,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"AGT,EDN1,NPR1"} {"Genesets":"GO:0009176","Term":"pyrimidine deoxyribonucleoside monophosphate metabolic process","Annotated":11,"Significant":3,"Expected":0.61,"Rank in p.value_classic":865,"p.value_elim":0.01952,"p.value_classic":0.01982,"Genes":"DPYS,TYMP,TYMS"} {"Genesets":"GO:0002833","Term":"positive regulation of response to biotic stimulus","Annotated":144,"Significant":29,"Expected":7.95,"Rank in p.value_classic":115,"p.value_elim":0.02028,"p.value_classic":9.6e-10,"Genes":"ACOD1,ADAM8,AIM2,CCL5,CD274,CLEC6A,DDX60,FCN1,GBP5,HLA-DRB1,HLA-E,HLA-F,HLA-G,IFI35,IL12A,IRF7,KLRK1,LAG3,LILRA2,LYN,NLRC5,NMI,NOD2,PYHIN1,SCIMP,SLAMF6,TLR8,ZBP1,ZNFX1"} {"Genesets":"GO:2000116","Term":"regulation of cysteine-type endopeptidase activity","Annotated":194,"Significant":18,"Expected":10.71,"Rank in p.value_classic":871,"p.value_elim":0.02047,"p.value_classic":0.02152,"Genes":"AIM2,BCL2L11,BIRC5,CARD16,FAS,GRAMD4,HGF,JAK2,KLF4,LAMP3,MEFV,MMP9,NLRP12,PMAIP1,PML,PSMB9,RIPK2,TNFSF10"} {"Genesets":"GO:0050792","Term":"regulation of viral process","Annotated":144,"Significant":26,"Expected":7.95,"Rank in p.value_classic":160,"p.value_elim":0.02056,"p.value_classic":7.5e-08,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CD28,CD74,CIITA,DYNLT1,FCN1,GBP7,HLA-DRB1,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,LAMP3,OAS2,PARP10,RSAD2,STAT1,TOP2A,TRIM22,TRIM31,ZNFX1"} {"Genesets":"GO:0046631","Term":"alpha-beta T cell activation","Annotated":140,"Significant":27,"Expected":7.73,"Rank in p.value_classic":140,"p.value_elim":0.02076,"p.value_classic":9.8e-09,"Genes":"BCL6,CD274,CD28,CD80,GPR183,HLA-A,HLA-DRA,HLA-DRB1,HLA-E,IL12A,IL12RB1,IL15,IL27,IRF1,ITK,JAK2,JAK3,PTGER4,RELB,RIPK2,RSAD2,SLAMF6,SOCS1,TBX21,TNFSF18,TNFSF8,ZC3H12A"} {"Genesets":"GO:0051899","Term":"membrane depolarization","Annotated":63,"Significant":8,"Expected":3.48,"Rank in p.value_classic":872,"p.value_elim":0.02131,"p.value_classic":0.02195,"Genes":"ANK2,CAMK2D,EDN1,KCNJ2,LRRK2,P2RX4,P2RX7,SCN4B"} {"Genesets":"GO:0002532","Term":"production of molecular mediator involved in inflammatory response","Annotated":63,"Significant":8,"Expected":3.48,"Rank in p.value_classic":873,"p.value_elim":0.02131,"p.value_classic":0.02195,"Genes":"APPL2,GBP5,LYN,MEFV,NCF1,NOD2,SLAMF8,ZC3H12A"} {"Genesets":"GO:0022600","Term":"digestive system process","Annotated":63,"Significant":8,"Expected":3.48,"Rank in p.value_classic":874,"p.value_elim":0.02131,"p.value_classic":0.02195,"Genes":"GCNT3,GHRL,HRH2,NOD2,SLC2A5,SNX10,TIFAB,TYMP"} {"Genesets":"GO:0009914","Term":"hormone transport","Annotated":209,"Significant":19,"Expected":11.54,"Rank in p.value_classic":883,"p.value_elim":0.02132,"p.value_classic":0.02244,"Genes":"AGT,CCL5,CD38,CRHBP,DAB2,EDN1,EXOC3L1,GHRL,GLUL,HCAR2,HLA-DRB1,IL1RN,JAK2,LRP5,LYN,OSM,SIDT2,SLC16A10,SRI"} {"Genesets":"GO:0019731","Term":"antibacterial humoral response","Annotated":20,"Significant":4,"Expected":1.1,"Rank in p.value_classic":875,"p.value_elim":0.0216,"p.value_classic":0.022,"Genes":"H2BC21,HLA-A,HLA-E,NOD2"} {"Genesets":"GO:0010880","Term":"regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum","Annotated":20,"Significant":4,"Expected":1.1,"Rank in p.value_classic":876,"p.value_elim":0.0216,"p.value_classic":0.022,"Genes":"ANK2,CAMK2D,SRI,TRDN"} {"Genesets":"GO:0086064","Term":"cell communication by electrical coupling involved in cardiac conduction","Annotated":20,"Significant":4,"Expected":1.1,"Rank in p.value_classic":877,"p.value_elim":0.0216,"p.value_classic":0.022,"Genes":"ATP1B2,CAMK2D,SRI,TRDN"} {"Genesets":"GO:0071378","Term":"cellular response to growth hormone stimulus","Annotated":20,"Significant":4,"Expected":1.1,"Rank in p.value_classic":878,"p.value_elim":0.0216,"p.value_classic":0.022,"Genes":"GHRL,JAK2,JAK3,LYN"} {"Genesets":"GO:0060396","Term":"growth hormone receptor signaling pathway","Annotated":20,"Significant":4,"Expected":1.1,"Rank in p.value_classic":879,"p.value_elim":0.0216,"p.value_classic":0.022,"Genes":"GHRL,JAK2,JAK3,LYN"} {"Genesets":"GO:0010447","Term":"response to acidic pH","Annotated":20,"Significant":4,"Expected":1.1,"Rank in p.value_classic":880,"p.value_elim":0.0216,"p.value_classic":0.022,"Genes":"ASIC1,CTSS,GPR31,PKD1L3"} {"Genesets":"GO:0051301","Term":"cell division","Annotated":572,"Significant":43,"Expected":31.58,"Rank in p.value_classic":893,"p.value_elim":0.0222,"p.value_classic":0.0241,"Genes":"ANLN,AURKB,BIRC5,BUB1B,CCNA2,CCNE2,CCNF,CDC25A,CDC6,CDCA3,CDCA5,CDK1,CDT1,CHMP4C,DLL1,DYNLT1,E2F8,EML4,ERCC6L,HELLS,KIF11,KIF18B,LBH,MAD2L1,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,OIP5,OSM,PRC1,RALB,SEPTIN4,SOX17,SPC24,SPC25,STMN1,TAL1,TOP2A,VEGFC,ZWINT"} {"Genesets":"GO:0050869","Term":"negative regulation of B cell activation","Annotated":30,"Significant":5,"Expected":1.66,"Rank in p.value_classic":884,"p.value_elim":0.02237,"p.value_classic":0.02286,"Genes":"BANK1,BCL6,CTLA4,LYN,TNFRSF21"} {"Genesets":"GO:0070570","Term":"regulation of neuron projection regeneration","Annotated":30,"Significant":5,"Expected":1.66,"Rank in p.value_classic":885,"p.value_elim":0.02237,"p.value_classic":0.02286,"Genes":"HGF,KLF4,KREMEN1,RTN4RL1,SCARF1"} {"Genesets":"GO:0050714","Term":"positive regulation of protein secretion","Annotated":101,"Significant":11,"Expected":5.58,"Rank in p.value_classic":887,"p.value_elim":0.02249,"p.value_classic":0.02332,"Genes":"ADAM8,ATP13A2,CD38,GHRL,GLUL,HCAR2,HLA-DRB1,JAK2,P2RX7,SRI,VEGFC"} {"Genesets":"GO:0043068","Term":"positive regulation of programmed cell death","Annotated":449,"Significant":41,"Expected":24.79,"Rank in p.value_classic":473,"p.value_elim":0.02264,"p.value_classic":0.00105,"Genes":"ADAM8,AGT,AIFM2,ATF3,BCL2L11,BCL6,CAMK2D,CCL5,CD274,CD40,CTLA4,CYLD,E2F1,FAS,G0S2,GADD45B,HCAR2,HLA-G,IDO1,IFIT2,IGF2R,IL12A,JAK2,LRRK2,LYN,MMP9,MYBL2,P2RX7,PDCD1,PMAIP1,PML,RAPGEF2,RIPK2,SCIN,SEPTIN4,TGM2,TNFSF10,TOP2A,UBD,ZBP1,ZC3H12A"} {"Genesets":"GO:0050918","Term":"positive chemotaxis","Annotated":52,"Significant":7,"Expected":2.87,"Rank in p.value_classic":888,"p.value_elim":0.02272,"p.value_classic":0.02334,"Genes":"CCL15,CCL5,CXCL10,HGF,NRP1,S1PR1,VEGFC"} {"Genesets":"GO:0044409","Term":"entry into host","Annotated":133,"Significant":18,"Expected":7.34,"Rank in p.value_classic":412,"p.value_elim":0.02276,"p.value_classic":0.00037,"Genes":"CD74,CD80,CDK1,CIITA,CXADR,DYNLT1,FCN1,HLA-DRB1,ICAM1,IFITM1,IFITM2,IFITM3,NRP1,SLAMF1,TPCN1,TRIM22,TRIM31,WWP1"} {"Genesets":"GO:0010876","Term":"lipid localization","Annotated":340,"Significant":31,"Expected":18.77,"Rank in p.value_classic":616,"p.value_elim":0.02283,"p.value_classic":0.00418,"Genes":"ABCB1,ABCC11,ABCG2,ACSL1,AGT,ANO4,APOL1,APOL2,APOL3,APOL4,APOL6,ATP8B1,C3,CEACAM1,DAB2,DGAT2,EDN1,EEPD1,GHRL,GRAMD1B,OSBPL6,P2RX4,P2RX7,RBP7,RNF213,SOAT1,TNFAIP8L3,TNFRSF11A,TTC39B,XKR6,ZC3H12A"} {"Genesets":"GO:0002274","Term":"myeloid leukocyte activation","Annotated":199,"Significant":27,"Expected":10.99,"Rank in p.value_classic":269,"p.value_elim":0.0232,"p.value_classic":0.00001,"Genes":"BATF2,BATF3,CCL5,CD300LF,CD74,CD93,CX3CR1,DYSF,IFI35,IL15,IL31RA,JAK2,KARS1,LILRA2,LRRK2,LYN,NMI,RELB,S100A13,SBNO2,SLAMF1,SLC11A1,STAP1,SUCNR1,TSPAN32,UBD,ZC3H12A"} {"Genesets":"GO:1902622","Term":"regulation of neutrophil migration","Annotated":41,"Significant":6,"Expected":2.26,"Rank in p.value_classic":891,"p.value_elim":0.02337,"p.value_classic":0.02394,"Genes":"ADAM8,CD74,EDN1,NOD2,SLAMF8,TNFAIP6"} {"Genesets":"GO:0042116","Term":"macrophage activation","Annotated":93,"Significant":15,"Expected":5.13,"Rank in p.value_classic":361,"p.value_elim":0.02374,"p.value_classic":0.00016,"Genes":"CD74,CD93,CX3CR1,DYSF,IFI35,IL31RA,JAK2,KARS1,LRRK2,NMI,SBNO2,SLC11A1,STAP1,SUCNR1,ZC3H12A"} {"Genesets":"GO:0045859","Term":"regulation of protein kinase activity","Annotated":558,"Significant":45,"Expected":30.81,"Rank in p.value_classic":685,"p.value_elim":0.02387,"p.value_classic":0.00673,"Genes":"ACSL1,ADAM8,AGT,CCL5,CCNA2,CCNE2,CCNF,CD40,CDC25A,CDC6,CDKN2C,CEACAM1,CLSPN,DAB1,DAB2,DEPTOR,DTNBP1,EDN1,FAM20A,GADD45B,GHRL,HBEGF,HGF,JAK2,KITLG,LRP5,LRRK2,LYN,MMD,MVP,NCAPG2,NCF1,NOD2,P2RX7,PKIB,PKMYT1,PPM1E,RALB,RAPGEF2,SLC11A1,SOCS1,STAP1,TNFRSF11A,VEGFC,WARS1"} {"Genesets":"GO:0002221","Term":"pattern recognition receptor signaling pathway","Annotated":159,"Significant":29,"Expected":8.78,"Rank in p.value_classic":143,"p.value_elim":0.02452,"p.value_classic":1e-08,"Genes":"ACOD1,AIM2,APPL2,CD300LF,CD40,COLEC12,CTSS,CYLD,DDX60,FCN1,GRAMD4,IFI35,IFIH1,IRF1,IRF7,LILRA2,LYN,MEFV,NMI,NOD2,RIPK2,RSAD2,SCIMP,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8"} {"Genesets":"GO:1902850","Term":"microtubule cytoskeleton organization involved in mitosis","Annotated":156,"Significant":15,"Expected":8.61,"Rank in p.value_classic":912,"p.value_elim":0.02454,"p.value_classic":0.02564,"Genes":"AURKB,BIRC5,CHMP4C,DYNLT1,KIF11,KIF15,MAD2L1,MYBL2,NDC80,NUF2,NUSAP1,PRC1,SPC25,STMN1,TACC2"} {"Genesets":"GO:0002704","Term":"negative regulation of leukocyte mediated immunity","Annotated":54,"Significant":14,"Expected":2.98,"Rank in p.value_classic":206,"p.value_elim":0.02461,"p.value_classic":8.9e-07,"Genes":"BCL6,CEACAM1,CR1L,CX3CR1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL4I1,JAK3,NOD2,SLAMF1,TBX21"} {"Genesets":"GO:0006874","Term":"cellular calcium ion homeostasis","Annotated":217,"Significant":23,"Expected":11.98,"Rank in p.value_classic":531,"p.value_elim":0.02462,"p.value_classic":0.00204,"Genes":"ANK2,ATP13A2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,LYN,MCOLN2,P2RX7,PML,SRI,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0045637","Term":"regulation of myeloid cell differentiation","Annotated":170,"Significant":16,"Expected":9.39,"Rank in p.value_classic":914,"p.value_elim":0.02472,"p.value_classic":0.02587,"Genes":"B2M,CD101,CD74,CEACAM1,DLL1,FAXDC2,HLA-DRB1,IRF7,KITLG,LILRB3,LYN,SCIN,STAT1,TAL1,TESC,TNFAIP6"} {"Genesets":"GO:0002687","Term":"positive regulation of leukocyte migration","Annotated":125,"Significant":16,"Expected":6.9,"Rank in p.value_classic":499,"p.value_elim":0.02474,"p.value_classic":0.00141,"Genes":"ADAM8,CCL5,CCL7,CCL8,CD74,CX3CR1,CXCL10,EDN1,ICAM1,IL12A,KITLG,LYVE1,P2RX4,SLAMF1,TNFSF18,VEGFC"} {"Genesets":"GO:0034121","Term":"regulation of toll-like receptor signaling pathway","Annotated":63,"Significant":13,"Expected":3.48,"Rank in p.value_classic":290,"p.value_elim":0.02478,"p.value_classic":0.00003,"Genes":"ACOD1,APPL2,CD300LF,GRAMD4,IFI35,IRF1,IRF7,LILRA2,LYN,NOD2,RSAD2,TICAM2,TLR5"} {"Genesets":"GO:0010564","Term":"regulation of cell cycle process","Annotated":634,"Significant":60,"Expected":35,"Rank in p.value_classic":285,"p.value_elim":0.02484,"p.value_classic":0.00003,"Genes":"ANLN,APPL2,ATF5,AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CHMP4C,CLSPN,CYP1A1,DTL,E2F1,E2F8,EDN1,FAM107A,FBXO6,FEN1,GTSE1,HLA-G,HORMAD1,KIF11,KIF15,KLF4,LRP5,MAD2L1,MIR503,MKI67,MUC1,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,ORC1,OVOL1,PKMYT1,PML,PRC1,PSME1,PSME2,RMI2,RRM2,SPC24,SPC25,TICRR,UBD,WDR76,ZWINT"} {"Genesets":"GO:0070207","Term":"protein homotrimerization","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":897,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"ASIC1,HLA-G,STEAP4"} {"Genesets":"GO:0061000","Term":"negative regulation of dendritic spine development","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":898,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"DTNBP1,FSTL4,GRIN3A"} {"Genesets":"GO:0043374","Term":"CD8-positive, alpha-beta T cell differentiation","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":899,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"IRF1,SOCS1,TNFSF8"} {"Genesets":"GO:0034135","Term":"regulation of toll-like receptor 2 signaling pathway","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":900,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"ACOD1,LYN,NOD2"} {"Genesets":"GO:0010649","Term":"regulation of cell communication by electrical coupling","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":901,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"CAMK2D,SRI,TRDN"} {"Genesets":"GO:0051132","Term":"NK T cell activation","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":902,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"IL12A,IL15,JAK2"} {"Genesets":"GO:0045006","Term":"DNA deamination","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":903,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G"} {"Genesets":"GO:0048291","Term":"isotype switching to IgG isotypes","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":904,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"CD28,CD40,TBX21"} {"Genesets":"GO:0009074","Term":"aromatic amino acid family catabolic process","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":905,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"IDO1,IDO2,IL4I1"} {"Genesets":"GO:2000846","Term":"regulation of corticosteroid hormone secretion","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":906,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"AGT,DAB2,GHRL"} {"Genesets":"GO:0045779","Term":"negative regulation of bone resorption","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":907,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"CD38,P2RX7,TMEM119"} {"Genesets":"GO:0002922","Term":"positive regulation of humoral immune response","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":908,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"ACOD1,C3,NOD2"} {"Genesets":"GO:0070493","Term":"thrombin-activated receptor signaling pathway","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":909,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"F2RL3,PLEK,STMN1"} {"Genesets":"GO:0035812","Term":"renal sodium excretion","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":910,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"AGT,EDN1,NPR1"} {"Genesets":"GO:0140289","Term":"protein mono-ADP-ribosylation","Annotated":12,"Significant":3,"Expected":0.66,"Rank in p.value_classic":911,"p.value_elim":0.02499,"p.value_classic":0.02536,"Genes":"PARP10,PARP12,PARP14"} {"Genesets":"GO:0036336","Term":"dendritic cell migration","Annotated":32,"Significant":8,"Expected":1.77,"Rank in p.value_classic":394,"p.value_elim":0.02516,"p.value_classic":0.00027,"Genes":"ASB2,CCL5,GPR183,IL12A,NLRP12,SLAMF1,SLAMF8,TNFSF18"} {"Genesets":"GO:0050896","Term":"response to stimulus","Annotated":6427,"Significant":494,"Expected":354.84,"Rank in p.value_classic":14,"p.value_elim":0.02525,"p.value_classic":3.1e-27,"Genes":"ABCB1,ABCG2,ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIFM2,AIM2,ALAS1,AMOT,ANK2,ANKH,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APPL2,ARAP2,ARMT1,ASB2,ASCL2,ASIC1,ATF3,ATP13A2,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C15orf48,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CBR3,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD101,CD1A,CD1C,CD274,CD28,CD300H,CD300LF,CD38,CD40,CD69,CD7,CD74,CD80,CDC25A,CDC45,CDC6,CDCA5,CDH5,CDK1,CDT1,CEACAM1,CELSR1,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CHRD,CIITA,CISH,CLEC10A,CLEC6A,CLIC5,CLSPN,CMAHP,CMPK2,COLEC12,COMP,CR1L,CRHBP,CSF2RB,CTLA4,CTNS,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DDX60,DEPDC7,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DMC1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F2,ECEL1,EDA,EDN1,EEPD1,EGR2,ENPP2,ENPP4,EPAS1,EPHB3,ERAP2,ESCO2,EXO1,F2RL3,FAM107A,FAM13A,FAM20A,FAS,FBXO6,FCN1,FEN1,FGD5,FGL1,FGL2,FLT3LG,FSTL4,FYB1,G0S2,GABRA3,GADD45B,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GFRA2,GGT5,GHRL,GINS2,GJD3,GLDN,GLIPR2,GLUL,GNG2,GPR183,GPR31,GRAMD1B,GRAMD4,GRIN3A,GRM8,GSDMA,GSDMD,GSTK1,GTPBP1,GTSE1,H2BC21,HAPLN3,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HORMAD1,HRH2,HSBP1L1,HSD3B7,HSH2D,ICAM1,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL4I1,INA,INSYN2A,IQGAP3,IRF1,IRF7,ISG20,ITGA7,ITGB1BP2,ITK,ITSN1,JAK2,JAK3,KARS1,KCNJ10,KCNJ2,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMP3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LITAF,LMTK2,LRP5,LRRK2,LTC4S,LY75,LYN,LYVE1,MAD2L1,MAF,MCF2L,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MCTP2,MEFV,MIR503,MMP25,MMP9,MRAS,MSRB1,MT2A,MTSS1,MUC1,MVP,MYBL2,MYOF,MYOZ2,NCAPG2,NCF1,NDC80,NECAB2,NEIL3,NLRC5,NLRP12,NMI,NOD2,NPR1,NRGN,NRK,NRP1,NUB1,NUCB1,NUF2,NXPH2,OAS2,OLFML2B,ONECUT2,OPTN,ORC1,OSM,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP10,PARP14,PCLAF,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PKD1L3,PLAAT3,PLCD3,PLCXD2,PLEK,PLPP4,PLXNA2,PMAIP1,PML,POLB,POLE2,PPM1E,PSMB10,PTGER4,PYHIN1,RAB20,RAD54B,RAD54L,RALB,RAPGEF2,RASGEF1C,RASGRF1,RECQL4,RELB,REPS2,RGS18,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF19B,RNF213,RSAD2,RSU1,RTN4RL1,RTP4,RUFY4,RXFP1,S100A10,S100A13,S1PR1,SBNO2,SCARF1,SCIMP,SCO2,SECTM1,SELENOP,SEMA6B,SEPTIN4,SERINC5,SERPING1,SESN3,SGPL1,SHCBP1,SIDT2,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SLC12A3,SLC20A1,SLC2A5,SNX10,SOCS1,SOX17,SP140,SPC24,SPC25,SRI,SSTR2,STAP1,STAT1,STAT2,STMN1,SUCNR1,SYT1,SYT6,TAGAP,TAP1,TAP2,TAPBP,TAPBPL,TBX21,TESC,TGM2,THBD,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TMEM255A,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TOP2A,TRABD2A,TRAFD1,TRDN,TRIM17,TRIM22,TRIM31,TSPAN32,TYMP,TYMS,UBD,UBE2T,UHRF1,USP53,VCAM1,VEGFC,VWCE,WDR76,WWP1,XAF1,XRCC2,XRN1,ZBP1,ZC3H12A,ZNFX1,ZWINT"} {"Genesets":"GO:0002040","Term":"sprouting angiogenesis","Annotated":116,"Significant":12,"Expected":6.4,"Rank in p.value_classic":924,"p.value_elim":0.02536,"p.value_classic":0.02634,"Genes":"CEACAM1,DLL1,E2F2,E2F8,GHRL,GLUL,IL12A,KLF4,MIR503,NRP1,RNF213,VEGFC"} {"Genesets":"GO:0007188","Term":"adenylate cyclase-modulating G protein-coupled receptor signaling pathway","Annotated":143,"Significant":14,"Expected":7.9,"Rank in p.value_classic":925,"p.value_elim":0.02547,"p.value_classic":0.02655,"Genes":"ADGRE5,ADGRG5,CXCL10,CXCL11,CXCL9,EDN1,GNG2,GRM8,PDE4B,PTGER4,RAPGEF2,RXFP1,S1PR1,SSTR2"} {"Genesets":"GO:0032480","Term":"negative regulation of type I interferon production","Annotated":31,"Significant":5,"Expected":1.71,"Rank in p.value_classic":921,"p.value_elim":0.02551,"p.value_classic":0.02606,"Genes":"ACOD1,CYLD,GBP7,NMI,RELB"} {"Genesets":"GO:0045730","Term":"respiratory burst","Annotated":31,"Significant":5,"Expected":1.71,"Rank in p.value_classic":922,"p.value_elim":0.02551,"p.value_classic":0.02606,"Genes":"NCF1,NCF1B,NCF1C,SLAMF8,SLC11A1"} {"Genesets":"GO:0055075","Term":"potassium ion homeostasis","Annotated":21,"Significant":4,"Expected":1.16,"Rank in p.value_classic":915,"p.value_elim":0.02555,"p.value_classic":0.02602,"Genes":"ATP1B2,KCNJ10,KCNJ2,SLC12A3"} {"Genesets":"GO:0046337","Term":"phosphatidylethanolamine metabolic process","Annotated":21,"Significant":4,"Expected":1.16,"Rank in p.value_classic":916,"p.value_elim":0.02555,"p.value_classic":0.02602,"Genes":"NAAA,PLAAT3,PLAAT4,PLB1"} {"Genesets":"GO:0046426","Term":"negative regulation of receptor signaling pathway via JAK-STAT","Annotated":21,"Significant":4,"Expected":1.16,"Rank in p.value_classic":917,"p.value_elim":0.02555,"p.value_classic":0.02602,"Genes":"DAB1,GBP7,PARP14,SOCS1"} {"Genesets":"GO:0009162","Term":"deoxyribonucleoside monophosphate metabolic process","Annotated":21,"Significant":4,"Expected":1.16,"Rank in p.value_classic":918,"p.value_elim":0.02555,"p.value_classic":0.02602,"Genes":"DPYS,TK1,TYMP,TYMS"} {"Genesets":"GO:0019226","Term":"transmission of nerve impulse","Annotated":42,"Significant":6,"Expected":2.32,"Rank in p.value_classic":926,"p.value_elim":0.02604,"p.value_classic":0.02667,"Genes":"AGT,GHRL,P2RX4,S1PR1,SPTBN4,TYMP"} {"Genesets":"GO:0001525","Term":"angiogenesis","Annotated":448,"Significant":42,"Expected":24.73,"Rank in p.value_classic":432,"p.value_elim":0.02618,"p.value_classic":0.00054,"Genes":"ADAM8,AGT,AMOT,BRCA1,C3,CD40,CDH5,CEACAM1,CX3CR1,CXCL10,CXCR3,CYSLTR1,DLL1,E2F2,E2F8,EDN1,ENPP2,EPAS1,EPHB3,GHRL,GLUL,HGF,HLA-G,IL12A,KLF4,MIR503,NPR1,NRP1,PDE3B,PLCD3,PML,RNF213,S1PR1,SAT1,SOX17,STAT1,THBS2,TNFAIP2,TYMP,VEGFC,WARS1,ZC3H12A"} {"Genesets":"GO:0072503","Term":"cellular divalent inorganic cation homeostasis","Annotated":247,"Significant":25,"Expected":13.64,"Rank in p.value_classic":554,"p.value_elim":0.0262,"p.value_classic":0.00251,"Genes":"ANK2,ATP13A2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,LYN,MCOLN2,MT2A,P2RX7,PML,SLC11A1,SRI,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0002684","Term":"positive regulation of immune system process","Annotated":715,"Significant":116,"Expected":39.48,"Rank in p.value_classic":15,"p.value_elim":0.0263,"p.value_classic":5e-27,"Genes":"ACOD1,ADAM8,AIM2,APPL2,B2M,BANK1,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL5,CCL7,CCL8,CD101,CD1A,CD1C,CD274,CD28,CD38,CD40,CD74,CD80,CEACAM1,CFB,CFH,CLEC6A,CR1L,CTLA4,CX3CR1,CXCL10,DDX60,EDN1,FCN1,FYB1,GBP1,GBP5,GPR183,GPR31,HCAR2,HLA-A,HLA-B,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IFI35,IL12A,IL12RB1,IL15,IL15RA,IL4I1,IRF7,ITK,JAK2,JAK3,KARS1,KITLG,KLRK1,LAG3,LILRA2,LRRK2,LYN,LYVE1,NLRC5,NMI,NOD2,P2RX4,P2RX7,PDCD1LG2,PDE4B,PLPP4,PYHIN1,RIPK2,RSAD2,SCIMP,SERPING1,SLAMF1,SLAMF6,SLC11A1,SOCS1,STAP1,TAP2,TBX21,TESC,TLR7,TLR8,TNFRSF21,TNFSF13B,TNFSF18,VCAM1,VEGFC,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0006873","Term":"cellular ion homeostasis","Annotated":396,"Significant":35,"Expected":21.86,"Rank in p.value_classic":614,"p.value_elim":0.02635,"p.value_classic":0.00402,"Genes":"AGT,ANK2,ATP13A2,ATP1B2,ATP6V0D2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNJ2,LRRK2,LYN,MCOLN2,MT2A,P2RX7,PML,RAB20,SCO2,SLAMF8,SLC11A1,SLC31A2,SRI,STEAP4,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0032692","Term":"negative regulation of interleukin-1 production","Annotated":28,"Significant":8,"Expected":1.55,"Rank in p.value_classic":330,"p.value_elim":0.0266,"p.value_classic":0.0001,"Genes":"CARD16,CEACAM1,CX3CR1,GHRL,MEFV,NLRP12,PML,ZC3H12A"} {"Genesets":"GO:0043065","Term":"positive regulation of apoptotic process","Annotated":439,"Significant":40,"Expected":24.24,"Rank in p.value_classic":490,"p.value_elim":0.02661,"p.value_classic":0.00125,"Genes":"ADAM8,AGT,AIFM2,ATF3,BCL2L11,BCL6,CAMK2D,CCL5,CD274,CD40,CTLA4,CYLD,E2F1,FAS,G0S2,GADD45B,HCAR2,HLA-G,IDO1,IFIT2,IGF2R,IL12A,JAK2,LYN,MMP9,MYBL2,P2RX7,PDCD1,PMAIP1,PML,RAPGEF2,RIPK2,SCIN,SEPTIN4,TGM2,TNFSF10,TOP2A,UBD,ZBP1,ZC3H12A"} {"Genesets":"GO:0071706","Term":"tumor necrosis factor superfamily cytokine production","Annotated":144,"Significant":14,"Expected":7.95,"Rank in p.value_classic":929,"p.value_elim":0.02685,"p.value_classic":0.02798,"Genes":"ADAM8,CD274,CX3CR1,GHRL,HLA-E,IFIH1,JAK2,LILRA2,LRRK2,NOD2,OAS2,RIPK2,SLAMF1,ZC3H12A"} {"Genesets":"GO:1903555","Term":"regulation of tumor necrosis factor superfamily cytokine production","Annotated":144,"Significant":14,"Expected":7.95,"Rank in p.value_classic":930,"p.value_elim":0.02685,"p.value_classic":0.02798,"Genes":"ADAM8,CD274,CX3CR1,GHRL,HLA-E,IFIH1,JAK2,LILRA2,LRRK2,NOD2,OAS2,RIPK2,SLAMF1,ZC3H12A"} {"Genesets":"GO:0071241","Term":"cellular response to inorganic substance","Annotated":186,"Significant":17,"Expected":10.27,"Rank in p.value_classic":932,"p.value_elim":0.0271,"p.value_classic":0.02839,"Genes":"ATP13A2,B2M,CAMK2D,CCNA2,CRHBP,CYP1A1,EDN1,HESX1,KCNJ10,LRRK2,MMP9,MT2A,NCF1,P2RX4,SLC12A3,SYT1,SYT6"} {"Genesets":"GO:1901988","Term":"negative regulation of cell cycle phase transition","Annotated":239,"Significant":32,"Expected":13.2,"Rank in p.value_classic":232,"p.value_elim":0.02712,"p.value_classic":2.9e-06,"Genes":"ATF5,AURKB,BIRC5,BRCA1,BTN2A2,BUB1B,CDC45,CDC6,CDK1,CDT1,CHMP4C,CLSPN,DTL,E2F1,FAM107A,FBXO6,GTSE1,HORMAD1,KLF4,MAD2L1,MIR503,MUC1,NDC80,NUF2,ORC1,OVOL1,PML,SPC24,SPC25,TICRR,WDR76,ZWINT"} {"Genesets":"GO:0045765","Term":"regulation of angiogenesis","Annotated":242,"Significant":28,"Expected":13.36,"Rank in p.value_classic":364,"p.value_elim":0.02729,"p.value_classic":0.00017,"Genes":"AGT,AMOT,BRCA1,C3,CD40,CDH5,CEACAM1,CX3CR1,CXCL10,CYSLTR1,DLL1,E2F2,ENPP2,GHRL,GLUL,HGF,HLA-G,KLF4,MIR503,NPR1,NRP1,PDE3B,PML,STAT1,THBS2,VEGFC,WARS1,ZC3H12A"} {"Genesets":"GO:0002753","Term":"cytoplasmic pattern recognition receptor signaling pathway","Annotated":54,"Significant":7,"Expected":2.98,"Rank in p.value_classic":931,"p.value_elim":0.0274,"p.value_classic":0.02813,"Genes":"CYLD,DDX60,IFIH1,IRF7,NOD2,RIPK2,TIFA"} {"Genesets":"GO:0002262","Term":"myeloid cell homeostasis","Annotated":145,"Significant":14,"Expected":8.01,"Rank in p.value_classic":936,"p.value_elim":0.02828,"p.value_classic":0.02947,"Genes":"ALAS1,B2M,BCL2L11,BCL6,EPAS1,HCAR2,JAK2,JAK3,KITLG,LYN,NCAPG2,PDE4B,STAT1,TAL1"} {"Genesets":"GO:0042325","Term":"regulation of phosphorylation","Annotated":1028,"Significant":86,"Expected":56.76,"Rank in p.value_classic":309,"p.value_elim":0.02862,"p.value_classic":0.00006,"Genes":"ACSL1,ADAM8,AGT,AURKB,BANK1,BIRC5,C3,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDKN2C,CEACAM1,CISH,CLEC6A,CLSPN,CX3CR1,DAB1,DAB2,DEPTOR,DTNBP1,EDN1,ENPP2,EPHB3,FAM20A,FAS,FAXDC2,GADD45B,GHRL,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IQGAP3,JAK2,KITLG,LIMK2,LMTK2,LRP5,LRRK2,LYN,MCM7,MMD,MMP9,MVP,NCAPG2,NCF1,NLRC5,NLRP12,NOD2,NRP1,OSM,P2RX7,PARP14,PID1,PKIB,PKMYT1,PPM1E,RALB,RAPGEF2,RIPK2,SLAMF8,SLC11A1,SLC2A6,SOCS1,SPTBN4,STAP1,STAT2,TLR7,TLR8,TMEM119,TNFAIP8L3,TNFRSF11A,TNFSF18,VEGFC,WARS1,ZC3H12A"} {"Genesets":"GO:0006826","Term":"iron ion transport","Annotated":43,"Significant":6,"Expected":2.37,"Rank in p.value_classic":944,"p.value_elim":0.0289,"p.value_classic":0.0296,"Genes":"B2M,FLVCR2,LMTK2,SLC11A1,SLC25A28,STEAP4"} {"Genesets":"GO:0042304","Term":"regulation of fatty acid biosynthetic process","Annotated":32,"Significant":5,"Expected":1.77,"Rank in p.value_classic":937,"p.value_elim":0.02891,"p.value_classic":0.02952,"Genes":"BRCA1,CD74,CEACAM1,PDK4,SLC45A3"} {"Genesets":"GO:0071459","Term":"protein localization to chromosome, centromeric region","Annotated":32,"Significant":5,"Expected":1.77,"Rank in p.value_classic":938,"p.value_elim":0.02891,"p.value_classic":0.02952,"Genes":"AURKB,BUB1B,CDK1,CDT1,NDC80"} {"Genesets":"GO:1901031","Term":"regulation of response to reactive oxygen species","Annotated":32,"Significant":5,"Expected":1.77,"Rank in p.value_classic":939,"p.value_elim":0.02891,"p.value_classic":0.02952,"Genes":"DHFR,GCH1,HGF,LRRK2,SESN3"} {"Genesets":"GO:0072529","Term":"pyrimidine-containing compound catabolic process","Annotated":32,"Significant":5,"Expected":1.77,"Rank in p.value_classic":940,"p.value_elim":0.02891,"p.value_classic":0.02952,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,DPYS,TYMP"} {"Genesets":"GO:1990573","Term":"potassium ion import across plasma membrane","Annotated":32,"Significant":5,"Expected":1.77,"Rank in p.value_classic":941,"p.value_elim":0.02891,"p.value_classic":0.02952,"Genes":"ATP1B2,KCNJ10,KCNJ15,KCNJ2,SLC12A3"} {"Genesets":"GO:0050433","Term":"regulation of catecholamine secretion","Annotated":32,"Significant":5,"Expected":1.77,"Rank in p.value_classic":942,"p.value_elim":0.02891,"p.value_classic":0.02952,"Genes":"ADORA3,AGT,DTNBP1,SYT1,SYT6"} {"Genesets":"GO:1903530","Term":"regulation of secretion by cell","Annotated":424,"Significant":36,"Expected":23.41,"Rank in p.value_classic":684,"p.value_elim":0.02923,"p.value_classic":0.00672,"Genes":"ADAM8,ADORA3,AGT,ASIC1,ATP13A2,CCL5,CD38,CEACAM1,CRHBP,DAB2,DTNBP1,EDN1,GHRL,GLUL,GRIN3A,HCAR2,HLA-DRB1,HLA-F,IL12A,JAK2,LRP5,LRRK2,LYN,MCTP2,OSM,P2RX4,P2RX7,RSAD2,S100A10,SEPTIN4,SIDT2,SRI,SYT1,SYT6,TNFRSF11A,VEGFC"} {"Genesets":"GO:0034762","Term":"regulation of transmembrane transport","Annotated":415,"Significant":36,"Expected":22.91,"Rank in p.value_classic":635,"p.value_elim":0.02955,"p.value_classic":0.00481,"Genes":"ABCB1,ACSL1,AGT,ANK2,APPL2,ATP1B2,C3,CACNA2D3,CAMK2D,CLIC5,CRHBP,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNJ10,KCNJ15,KCNJ2,LYN,MMP9,P2RX4,P2RX7,PDE4B,PID1,PIM1,PML,RASGRF1,SCN4B,SLC31A2,SRI,TESC,TMEM109,TPCN1,TRDN"} {"Genesets":"GO:0071359","Term":"cellular response to dsRNA","Annotated":22,"Significant":4,"Expected":1.21,"Rank in p.value_classic":948,"p.value_elim":0.02991,"p.value_classic":0.03045,"Genes":"COLEC12,IFIH1,P2RX7,RALB"} {"Genesets":"GO:0014829","Term":"vascular associated smooth muscle contraction","Annotated":22,"Significant":4,"Expected":1.21,"Rank in p.value_classic":949,"p.value_elim":0.02991,"p.value_classic":0.03045,"Genes":"AGT,CD38,COMP,EDN1"} {"Genesets":"GO:0021602","Term":"cranial nerve morphogenesis","Annotated":22,"Significant":4,"Expected":1.21,"Rank in p.value_classic":950,"p.value_elim":0.02991,"p.value_classic":0.03045,"Genes":"ATP8B1,EGR2,NRP1,TIFAB"} {"Genesets":"GO:0071248","Term":"cellular response to metal ion","Annotated":160,"Significant":15,"Expected":8.83,"Rank in p.value_classic":956,"p.value_elim":0.02994,"p.value_classic":0.03123,"Genes":"ATP13A2,B2M,CAMK2D,CRHBP,CYP1A1,EDN1,HESX1,KCNJ10,LRRK2,MMP9,MT2A,NCF1,P2RX4,SYT1,SYT6"} {"Genesets":"GO:0007062","Term":"sister chromatid cohesion","Annotated":55,"Significant":7,"Expected":3.04,"Rank in p.value_classic":954,"p.value_elim":0.02996,"p.value_classic":0.03076,"Genes":"BUB1B,CDCA5,DSCC1,ESCO2,FEN1,HORMAD1,MEIKIN"} {"Genesets":"GO:0034142","Term":"toll-like receptor 4 signaling pathway","Annotated":34,"Significant":9,"Expected":1.88,"Rank in p.value_classic":317,"p.value_elim":0.03064,"p.value_classic":0.00007,"Genes":"ACOD1,APPL2,IFI35,LILRA2,LYN,NMI,RIPK2,SCIMP,TICAM2"} {"Genesets":"GO:1905155","Term":"positive regulation of membrane invagination","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":959,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"APPL2,C3,STAP1"} {"Genesets":"GO:0048012","Term":"hepatocyte growth factor receptor signaling pathway","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":960,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"HGF,NRP1,STMN1"} {"Genesets":"GO:0002371","Term":"dendritic cell cytokine production","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":961,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"JAK3,NOD2,SCIMP"} {"Genesets":"GO:0051255","Term":"spindle midzone assembly","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":962,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"AURKB,BIRC5,PRC1"} {"Genesets":"GO:2000318","Term":"positive regulation of T-helper 17 type immune response","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":963,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"CLEC6A,IL12RB1,JAK2"} {"Genesets":"GO:0002730","Term":"regulation of dendritic cell cytokine production","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":964,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"JAK3,NOD2,SCIMP"} {"Genesets":"GO:0002517","Term":"T cell tolerance induction","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":965,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"HLA-B,HLA-G,IDO1"} {"Genesets":"GO:0044062","Term":"regulation of excretion","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":966,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"AGT,EDN1,NPR1"} {"Genesets":"GO:0060100","Term":"positive regulation of phagocytosis, engulfment","Annotated":13,"Significant":3,"Expected":0.72,"Rank in p.value_classic":967,"p.value_elim":0.03119,"p.value_classic":0.03164,"Genes":"APPL2,C3,STAP1"} {"Genesets":"GO:0010950","Term":"positive regulation of endopeptidase activity","Annotated":147,"Significant":14,"Expected":8.12,"Rank in p.value_classic":968,"p.value_elim":0.03132,"p.value_classic":0.03261,"Genes":"AIM2,BCL2L11,FAS,GRAMD4,JAK2,LYN,MEFV,NLRP12,PMAIP1,PML,PSME1,PSME2,RIPK2,TNFSF10"} {"Genesets":"GO:0006836","Term":"neurotransmitter transport","Annotated":161,"Significant":15,"Expected":8.89,"Rank in p.value_classic":972,"p.value_elim":0.03141,"p.value_classic":0.03276,"Genes":"ASIC1,DTNBP1,ERC2,GRIN3A,KCNJ10,LRRK2,MCTP2,P2RX7,PRRT2,SLC18A1,SLC6A12,STX11,SV2B,SYNGR3,SYT1"} {"Genesets":"GO:1901342","Term":"regulation of vasculature development","Annotated":245,"Significant":28,"Expected":13.53,"Rank in p.value_classic":380,"p.value_elim":0.03152,"p.value_classic":0.00021,"Genes":"AGT,AMOT,BRCA1,C3,CD40,CDH5,CEACAM1,CX3CR1,CXCL10,CYSLTR1,DLL1,E2F2,ENPP2,GHRL,GLUL,HGF,HLA-G,KLF4,MIR503,NPR1,NRP1,PDE3B,PML,STAT1,THBS2,VEGFC,WARS1,ZC3H12A"} {"Genesets":"GO:0051347","Term":"positive regulation of transferase activity","Annotated":490,"Significant":40,"Expected":27.05,"Rank in p.value_classic":711,"p.value_elim":0.03155,"p.value_classic":0.00846,"Genes":"ACSL1,ADAM8,AGT,AURKB,CCL5,CD40,CD74,CDC6,CLSPN,DAB1,DSCC1,DTX3L,EDN1,EPHB3,FAM20A,GHRL,GINS2,HBEGF,HLA-DRB1,JAK2,KITLG,KLF4,LMTK2,LRRK2,LYN,MMD,NCF1,NOD2,P2RX7,PKIB,PLAAT4,RALB,RAPGEF2,SERINC5,SLC11A1,SOCS1,STAP1,TNFAIP8L3,TNFRSF11A,VEGFC"} {"Genesets":"GO:0031103","Term":"axon regeneration","Annotated":44,"Significant":6,"Expected":2.43,"Rank in p.value_classic":969,"p.value_elim":0.03197,"p.value_classic":0.03273,"Genes":"DHFR,JAK2,KLF4,KREMEN1,RTN4RL1,SCARF1"} {"Genesets":"GO:0007218","Term":"neuropeptide signaling pathway","Annotated":44,"Significant":6,"Expected":2.43,"Rank in p.value_classic":970,"p.value_elim":0.03197,"p.value_classic":0.03273,"Genes":"CYSLTR1,CYSLTR2,ECEL1,NXPH2,RAPGEF2,SSTR2"} {"Genesets":"GO:0032677","Term":"regulation of interleukin-8 production","Annotated":68,"Significant":8,"Expected":3.75,"Rank in p.value_classic":973,"p.value_elim":0.03209,"p.value_classic":0.03302,"Genes":"CD74,FCN1,KLF4,LILRA2,NOD2,TLR5,TLR7,TLR8"} {"Genesets":"GO:0032637","Term":"interleukin-8 production","Annotated":68,"Significant":8,"Expected":3.75,"Rank in p.value_classic":974,"p.value_elim":0.03209,"p.value_classic":0.03302,"Genes":"CD74,FCN1,KLF4,LILRA2,NOD2,TLR5,TLR7,TLR8"} {"Genesets":"GO:1903900","Term":"regulation of viral life cycle","Annotated":125,"Significant":24,"Expected":6.9,"Rank in p.value_classic":159,"p.value_elim":0.03258,"p.value_classic":7.1e-08,"Genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CD28,CD74,CIITA,FCN1,GBP7,HLA-DRB1,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,LAMP3,OAS2,PARP10,RSAD2,TOP2A,TRIM22,TRIM31,ZNFX1"} {"Genesets":"GO:0043330","Term":"response to exogenous dsRNA","Annotated":33,"Significant":5,"Expected":1.82,"Rank in p.value_classic":976,"p.value_elim":0.03259,"p.value_classic":0.03327,"Genes":"COLEC12,IFIH1,NOD2,RALB,RIPK2"} {"Genesets":"GO:0006471","Term":"protein ADP-ribosylation","Annotated":33,"Significant":5,"Expected":1.82,"Rank in p.value_classic":977,"p.value_elim":0.03259,"p.value_classic":0.03327,"Genes":"ART3,PARP10,PARP12,PARP14,WARS1"} {"Genesets":"GO:0042572","Term":"retinol metabolic process","Annotated":33,"Significant":5,"Expected":1.82,"Rank in p.value_classic":978,"p.value_elim":0.03259,"p.value_classic":0.03327,"Genes":"CYP1A1,DGAT2,DHRS3,DHRS9,PLB1"} {"Genesets":"GO:0050432","Term":"catecholamine secretion","Annotated":33,"Significant":5,"Expected":1.82,"Rank in p.value_classic":979,"p.value_elim":0.03259,"p.value_classic":0.03327,"Genes":"ADORA3,AGT,DTNBP1,SYT1,SYT6"} {"Genesets":"GO:0055082","Term":"cellular chemical homeostasis","Annotated":512,"Significant":42,"Expected":28.27,"Rank in p.value_classic":682,"p.value_elim":0.03273,"p.value_classic":0.00652,"Genes":"AGT,ANK2,ATP13A2,ATP1B2,ATP6V0D2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,DGAT2,EDN1,F2RL3,GHRL,HLA-DRB1,ICAM1,KCNJ2,LRP5,LRRK2,LYN,MCOLN2,MT2A,NCF1,P2RX7,PML,RAB20,SCO2,SIDT2,SLAMF8,SLC11A1,SLC31A2,SRI,STEAP4,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0002790","Term":"peptide secretion","Annotated":162,"Significant":15,"Expected":8.94,"Rank in p.value_classic":982,"p.value_elim":0.03294,"p.value_classic":0.03435,"Genes":"CCL5,CD38,CD74,CRHBP,EDN1,EXOC3L1,GHRL,GLUL,HLA-DRB1,IL1RN,JAK2,LRP5,SIDT2,SLC16A10,SRI"} {"Genesets":"GO:0050900","Term":"leukocyte migration","Annotated":320,"Significant":46,"Expected":17.67,"Rank in p.value_classic":123,"p.value_elim":0.03311,"p.value_classic":2e-09,"Genes":"ADAM8,ASB2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,EDN1,GPR183,HSD3B7,ICAM1,IL12A,ITGA7,KITLG,KLRK1,LYN,LYVE1,MCOLN2,MMP9,NLRP12,NOD2,P2RX4,PADI2,PDE4B,PTGER4,S1PR1,SELL,SLAMF1,SLAMF8,STAP1,TBX21,TNFAIP6,TNFRSF11A,TNFSF18,VCAM1,VEGFC"} {"Genesets":"GO:0043269","Term":"regulation of ion transport","Annotated":479,"Significant":43,"Expected":26.45,"Rank in p.value_classic":478,"p.value_elim":0.03358,"p.value_classic":0.00112,"Genes":"ABCB1,ADORA3,AGT,ANK2,ATP1B2,ATP8B1,B2M,CACNA2D3,CAMK2D,CCL5,CLIC5,CRHBP,CTSS,CXCL10,CXCL11,CXCL9,DTNBP1,EDN1,F2RL3,JAK3,KCNJ10,KCNJ15,KCNJ2,LILRA2,LYN,MMP9,P2RX4,P2RX7,PDE4B,PLPP4,PML,RASGRF1,SCN4B,SLC31A2,SPTBN4,SRI,SYT1,SYT6,TESC,TMEM109,TNFRSF11A,TPCN1,TRDN"} {"Genesets":"GO:0055080","Term":"cation homeostasis","Annotated":458,"Significant":45,"Expected":25.29,"Rank in p.value_classic":346,"p.value_elim":0.03366,"p.value_classic":0.00012,"Genes":"AGT,ANK2,ANKH,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,EPAS1,F2RL3,FAM20A,KCNJ10,KCNJ2,LRRK2,LYN,MCOLN2,MT2A,NPR1,P2RX7,PDK4,PML,RAB20,SCO2,SLAMF8,SLC11A1,SLC12A3,SLC25A28,SLC31A2,SNX10,SRI,STEAP4,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0045055","Term":"regulated exocytosis","Annotated":191,"Significant":17,"Expected":10.55,"Rank in p.value_classic":988,"p.value_elim":0.0338,"p.value_classic":0.03535,"Genes":"CEACAM1,CRHBP,DTNBP1,ERC2,GRIN3A,HLA-F,LRRK2,LYN,P2RX7,PLEK,PRRT2,S100A13,SCIN,STX11,SYNGR3,SYT1,SYT6"} {"Genesets":"GO:0034765","Term":"regulation of ion transmembrane transport","Annotated":343,"Significant":31,"Expected":18.94,"Rank in p.value_classic":633,"p.value_elim":0.03397,"p.value_classic":0.00475,"Genes":"ABCB1,AGT,ANK2,ATP1B2,CACNA2D3,CAMK2D,CLIC5,CRHBP,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNJ10,KCNJ15,KCNJ2,LYN,MMP9,P2RX4,P2RX7,PDE4B,PML,RASGRF1,SCN4B,SLC31A2,SRI,TESC,TMEM109,TPCN1,TRDN"} {"Genesets":"GO:0033002","Term":"muscle cell proliferation","Annotated":177,"Significant":16,"Expected":9.77,"Rank in p.value_classic":992,"p.value_elim":0.03424,"p.value_classic":0.03576,"Genes":"AGT,CCL5,CDK1,CXADR,EDN1,HBEGF,HGF,IL12A,IL15,JAK2,MIR503,MMP9,NPR1,PIM1,S1PR1,STAT1"} {"Genesets":"GO:0140013","Term":"meiotic nuclear division","Annotated":135,"Significant":13,"Expected":7.45,"Rank in p.value_classic":991,"p.value_elim":0.03436,"p.value_classic":0.0357,"Genes":"BCL2L11,BUB1B,CCNE2,DMC1,HORMAD1,MEIKIN,NCAPH,NDC80,NUF2,RAD54B,RAD54L,TDRD9,TOP2A"} {"Genesets":"GO:0044843","Term":"cell cycle G1/S phase transition","Annotated":235,"Significant":20,"Expected":12.97,"Rank in p.value_classic":997,"p.value_elim":0.03437,"p.value_classic":0.03611,"Genes":"APPL2,BACH1,BTN2A2,CCNA2,CCNE2,CDC25A,CDC6,CDKN2C,CYP1A1,E2F1,FAM107A,GTSE1,IQGAP3,KLF4,MIR503,MUC1,PML,PSME1,PSME2,RRM2"} {"Genesets":"GO:0001932","Term":"regulation of protein phosphorylation","Annotated":904,"Significant":78,"Expected":49.91,"Rank in p.value_classic":304,"p.value_elim":0.0344,"p.value_classic":0.00005,"Genes":"ACSL1,ADAM8,AGT,AURKB,BANK1,BIRC5,C3,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDKN2C,CEACAM1,CLEC6A,CLSPN,CX3CR1,DAB1,DAB2,DEPTOR,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,GADD45B,GHRL,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IQGAP3,JAK2,KITLG,LIMK2,LRP5,LRRK2,LYN,MMD,MMP9,MVP,NCAPG2,NCF1,NLRP12,NOD2,NRP1,OSM,P2RX7,PARP14,PID1,PKIB,PKMYT1,PPM1E,RALB,RAPGEF2,RIPK2,SLC11A1,SOCS1,SPTBN4,STAP1,STAT2,TLR7,TLR8,TMEM119,TNFRSF11A,TNFSF18,VEGFC,WARS1,ZC3H12A"} {"Genesets":"GO:0046883","Term":"regulation of hormone secretion","Annotated":163,"Significant":15,"Expected":9,"Rank in p.value_classic":993,"p.value_elim":0.03452,"p.value_classic":0.03599,"Genes":"AGT,CCL5,CD38,CRHBP,DAB2,EDN1,GHRL,GLUL,HCAR2,HLA-DRB1,JAK2,LRP5,OSM,SIDT2,SRI"} {"Genesets":"GO:2000045","Term":"regulation of G1/S transition of mitotic cell cycle","Annotated":149,"Significant":14,"Expected":8.23,"Rank in p.value_classic":994,"p.value_elim":0.03458,"p.value_classic":0.03599,"Genes":"APPL2,BTN2A2,CDC6,CDKN2C,CYP1A1,E2F1,FAM107A,GTSE1,KLF4,MUC1,PML,PSME1,PSME2,RRM2"} {"Genesets":"GO:0002698","Term":"negative regulation of immune effector process","Annotated":97,"Significant":19,"Expected":5.36,"Rank in p.value_classic":219,"p.value_elim":0.03458,"p.value_classic":1.2e-06,"Genes":"BCL6,CEACAM1,CR1L,CX3CR1,FGL2,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL4I1,JAK3,NOD2,SERPING1,SLAMF1,SLAMF8,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:0051383","Term":"kinetochore organization","Annotated":23,"Significant":4,"Expected":1.27,"Rank in p.value_classic":983,"p.value_elim":0.03468,"p.value_classic":0.0353,"Genes":"CDT1,CENPK,NDC80,NUF2"} {"Genesets":"GO:0032703","Term":"negative regulation of interleukin-2 production","Annotated":23,"Significant":4,"Expected":1.27,"Rank in p.value_classic":984,"p.value_elim":0.03468,"p.value_classic":0.0353,"Genes":"GBP1,LAG3,NOD2,TBX21"} {"Genesets":"GO:1904893","Term":"negative regulation of receptor signaling pathway via STAT","Annotated":23,"Significant":4,"Expected":1.27,"Rank in p.value_classic":985,"p.value_elim":0.03468,"p.value_classic":0.0353,"Genes":"DAB1,GBP7,PARP14,SOCS1"} {"Genesets":"GO:0007628","Term":"adult walking behavior","Annotated":23,"Significant":4,"Expected":1.27,"Rank in p.value_classic":986,"p.value_elim":0.03468,"p.value_classic":0.0353,"Genes":"CTNS,DAB1,KCNJ10,SPTBN4"} {"Genesets":"GO:0009219","Term":"pyrimidine deoxyribonucleotide metabolic process","Annotated":23,"Significant":4,"Expected":1.27,"Rank in p.value_classic":987,"p.value_elim":0.03468,"p.value_classic":0.0353,"Genes":"CMPK2,DPYS,TYMP,TYMS"} {"Genesets":"GO:0050853","Term":"B cell receptor signaling pathway","Annotated":45,"Significant":6,"Expected":2.48,"Rank in p.value_classic":995,"p.value_elim":0.03524,"p.value_classic":0.03607,"Genes":"BANK1,CD38,CTLA4,ITK,LYN,STAP1"} {"Genesets":"GO:0033209","Term":"tumor necrosis factor-mediated signaling pathway","Annotated":95,"Significant":10,"Expected":5.24,"Rank in p.value_classic":999,"p.value_elim":0.03531,"p.value_classic":0.03647,"Genes":"AIM2,CARD16,CASP4,CYLD,FAS,JAK2,STAT1,TNFRSF11A,TNFSF13B,TNFSF18"} {"Genesets":"GO:0032755","Term":"positive regulation of interleukin-6 production","Annotated":82,"Significant":9,"Expected":4.53,"Rank in p.value_classic":998,"p.value_elim":0.03537,"p.value_classic":0.03645,"Genes":"CD74,IFIH1,LILRA2,NOD2,P2RX7,RIPK2,SCIMP,TLR7,TLR8"} {"Genesets":"GO:0019882","Term":"antigen processing and presentation","Annotated":96,"Significant":35,"Expected":5.3,"Rank in p.value_classic":21,"p.value_elim":0.03546,"p.value_classic":3.2e-20,"Genes":"B2M,CD1A,CD1C,CD74,CTSS,ERAP2,FGL2,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,NOD2,PSMB8,PSME1,RELB,SLC11A1,TAP1,TAP2,TAPBP,TAPBPL"} {"Genesets":"GO:0055117","Term":"regulation of cardiac muscle contraction","Annotated":57,"Significant":7,"Expected":3.15,"Rank in p.value_classic":1000,"p.value_elim":0.03556,"p.value_classic":0.03649,"Genes":"ANK2,CAMK2D,KCNJ2,P2RX4,PDE4B,SRI,ZC3H12A"} {"Genesets":"GO:0070373","Term":"negative regulation of ERK1 and ERK2 cascade","Annotated":57,"Significant":7,"Expected":3.15,"Rank in p.value_classic":1001,"p.value_elim":0.03556,"p.value_classic":0.03649,"Genes":"ATF3,BTN2A2,DAB2,GBP1,LYN,MIR503,NLRP12"} {"Genesets":"GO:2001236","Term":"regulation of extrinsic apoptotic signaling pathway","Annotated":136,"Significant":13,"Expected":7.51,"Rank in p.value_classic":1006,"p.value_elim":0.03617,"p.value_classic":0.03757,"Genes":"AGT,ATF3,BCL2L14,BRCA1,CYLD,DEPTOR,G0S2,HGF,ICAM1,NRP1,PMAIP1,PML,TNFSF10"} {"Genesets":"GO:0010508","Term":"positive regulation of autophagy","Annotated":136,"Significant":13,"Expected":7.51,"Rank in p.value_classic":1007,"p.value_elim":0.03617,"p.value_classic":0.03757,"Genes":"BCL2L11,CALCOCO2,LRRK2,MEFV,NOD2,OPTN,RALB,RIPK2,RUFY4,SESN3,TPCN1,TRIM22,ZC3H12A"} {"Genesets":"GO:0008015","Term":"blood circulation","Annotated":380,"Significant":38,"Expected":20.98,"Rank in p.value_classic":396,"p.value_elim":0.03648,"p.value_classic":0.00028,"Genes":"ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CD38,CDH5,CEACAM1,COMP,CXADR,CXCL10,CYSLTR1,DLL1,EDN1,EPAS1,ERAP2,GCH1,GHRL,GJD3,HBEGF,HRH2,JAK2,KCNJ2,LRP5,MYOF,NPR1,P2RX4,PDE4B,SCN4B,SERPING1,SLC2A5,SPTBN4,SRI,STAT1,SUCNR1,TRDN,VEGFC,ZC3H12A"} {"Genesets":"GO:1900047","Term":"negative regulation of hemostasis","Annotated":34,"Significant":5,"Expected":1.88,"Rank in p.value_classic":1002,"p.value_elim":0.03654,"p.value_classic":0.0373,"Genes":"CEACAM1,COMP,EDN1,SERPING1,THBD"} {"Genesets":"GO:0007095","Term":"mitotic G2 DNA damage checkpoint signaling","Annotated":34,"Significant":5,"Expected":1.88,"Rank in p.value_classic":1003,"p.value_elim":0.03654,"p.value_classic":0.0373,"Genes":"BRCA1,CDK1,CLSPN,DTL,TICRR"} {"Genesets":"GO:1903115","Term":"regulation of actin filament-based movement","Annotated":34,"Significant":5,"Expected":1.88,"Rank in p.value_classic":1004,"p.value_elim":0.03654,"p.value_classic":0.0373,"Genes":"ANK2,CAMK2D,KCNJ2,PDE4B,SRI"} {"Genesets":"GO:2000108","Term":"positive regulation of leukocyte apoptotic process","Annotated":26,"Significant":10,"Expected":1.44,"Rank in p.value_classic":190,"p.value_elim":0.03726,"p.value_classic":5.9e-07,"Genes":"ADAM8,BCL2L11,CCL5,CD274,HCAR2,IDO1,LYN,P2RX7,PDCD1,RAPGEF2"} {"Genesets":"GO:0045132","Term":"meiotic chromosome segregation","Annotated":70,"Significant":8,"Expected":3.86,"Rank in p.value_classic":1009,"p.value_elim":0.0373,"p.value_classic":0.03835,"Genes":"BUB1B,CCNE2,DMC1,HORMAD1,MEIKIN,NCAPH,NUF2,TOP2A"} {"Genesets":"GO:0002761","Term":"regulation of myeloid leukocyte differentiation","Annotated":96,"Significant":10,"Expected":5.3,"Rank in p.value_classic":1018,"p.value_elim":0.03756,"p.value_classic":0.03878,"Genes":"CD101,CD74,CEACAM1,HLA-DRB1,IRF7,KITLG,LILRB3,LYN,TESC,TNFAIP6"} {"Genesets":"GO:0048144","Term":"fibroblast proliferation","Annotated":96,"Significant":10,"Expected":5.3,"Rank in p.value_classic":1019,"p.value_elim":0.03756,"p.value_classic":0.03878,"Genes":"AGT,CCNA2,CD74,CDC6,CDK1,E2F1,E2F8,GNG2,PARP10,PML"} {"Genesets":"GO:0010952","Term":"positive regulation of peptidase activity","Annotated":165,"Significant":15,"Expected":9.11,"Rank in p.value_classic":1022,"p.value_elim":0.03784,"p.value_classic":0.03943,"Genes":"AIM2,ANTXR1,BCL2L11,FAS,GRAMD4,JAK2,LYN,MEFV,NLRP12,PMAIP1,PML,PSME1,PSME2,RIPK2,TNFSF10"} {"Genesets":"GO:0033033","Term":"negative regulation of myeloid cell apoptotic process","Annotated":14,"Significant":3,"Expected":0.77,"Rank in p.value_classic":1012,"p.value_elim":0.03811,"p.value_classic":0.03866,"Genes":"IRF7,KITLG,NOD2"} {"Genesets":"GO:0035435","Term":"phosphate ion transmembrane transport","Annotated":14,"Significant":3,"Expected":0.77,"Rank in p.value_classic":1013,"p.value_elim":0.03811,"p.value_classic":0.03866,"Genes":"ANKH,SLC20A1,SLC37A1"} {"Genesets":"GO:0006206","Term":"pyrimidine nucleobase metabolic process","Annotated":14,"Significant":3,"Expected":0.77,"Rank in p.value_classic":1014,"p.value_elim":0.03811,"p.value_classic":0.03866,"Genes":"DPYS,TYMP,TYMS"} {"Genesets":"GO:1902287","Term":"semaphorin-plexin signaling pathway involved in axon guidance","Annotated":14,"Significant":3,"Expected":0.77,"Rank in p.value_classic":1015,"p.value_elim":0.03811,"p.value_classic":0.03866,"Genes":"EDN1,NRP1,PLXNA2"} {"Genesets":"GO:0046851","Term":"negative regulation of bone remodeling","Annotated":14,"Significant":3,"Expected":0.77,"Rank in p.value_classic":1016,"p.value_elim":0.03811,"p.value_classic":0.03866,"Genes":"CD38,P2RX7,TMEM119"} {"Genesets":"GO:0031347","Term":"regulation of defense response","Annotated":521,"Significant":79,"Expected":28.76,"Rank in p.value_classic":37,"p.value_elim":0.03853,"p.value_classic":1e-16,"Genes":"ACOD1,ADAM8,AGT,AIM2,APOBEC3G,APPL2,BCL6,C3,CASP4,CCL5,CD28,CDH5,CEACAM1,CFH,CLEC6A,CYLD,DTX3L,FCN1,FGL2,GBP5,GHRL,GPR31,HGF,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IL12A,IL12RB1,IL15,IL22RA2,IL27,IRF1,IRF7,JAK2,KARS1,KLF4,KLRK1,LAG3,LILRA2,LRRK2,LYN,MEFV,MMP9,NCF1,NLRC5,NLRP12,NMI,NOD2,OPTN,OSM,PARP14,PTGER4,PYHIN1,RIPK2,SBNO2,SERPING1,SLAMF6,SLAMF8,SOCS1,STAP1,STAT1,STAT2,SUCNR1,TLR10,TLR7,TLR8,TNFAIP6,TNFRSF11A,TNFSF18,TRAFD1,TSPAN32,ZBP1,ZC3H12A,ZNFX1"} {"Genesets":"GO:0031663","Term":"lipopolysaccharide-mediated signaling pathway","Annotated":58,"Significant":7,"Expected":3.2,"Rank in p.value_classic":1023,"p.value_elim":0.03861,"p.value_classic":0.03961,"Genes":"ACOD1,CARD16,CCL5,LILRA2,LYN,RIPK2,SCIMP"} {"Genesets":"GO:0002443","Term":"leukocyte mediated immunity","Annotated":299,"Significant":62,"Expected":16.51,"Rank in p.value_classic":22,"p.value_elim":0.03961,"p.value_classic":4.2e-20,"Genes":"B2M,BCL6,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD1A,CD1C,CD28,CD40,CD74,CEACAM1,CR1L,CSF2RB,CX3CR1,EXO1,HLA-A,HLA-B,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL4I1,IRF7,JAK3,KLRK1,LAG3,LYN,NOD2,P2RX7,RNF19B,RSAD2,S100A13,SCIMP,SERPING1,SLAMF1,SLAMF6,SLAMF7,STAP1,TAP2,TBX21,TLR8"} {"Genesets":"GO:0048660","Term":"regulation of smooth muscle cell proliferation","Annotated":124,"Significant":12,"Expected":6.85,"Rank in p.value_classic":1030,"p.value_elim":0.03969,"p.value_classic":0.04114,"Genes":"AGT,CCL5,EDN1,HBEGF,IL12A,IL15,JAK2,MIR503,MMP9,NPR1,S1PR1,STAT1"} {"Genesets":"GO:0070372","Term":"regulation of ERK1 and ERK2 cascade","Annotated":236,"Significant":28,"Expected":13.03,"Rank in p.value_classic":337,"p.value_elim":0.03982,"p.value_classic":0.00011,"Genes":"ATF3,BTN2A2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD74,CEACAM1,DAB2,GBP1,GLIPR2,GPR183,HLA-DRB1,ICAM1,LYN,MIR503,NECAB2,NLRP12,NOD2,NRP1,RAPGEF2,RIPK2,SCIMP,SLAMF1,TNFAIP8L3,TNFRSF11A"} {"Genesets":"GO:0090659","Term":"walking behavior","Annotated":24,"Significant":4,"Expected":1.33,"Rank in p.value_classic":1025,"p.value_elim":0.03987,"p.value_classic":0.04057,"Genes":"CTNS,DAB1,KCNJ10,SPTBN4"} {"Genesets":"GO:0010644","Term":"cell communication by electrical coupling","Annotated":24,"Significant":4,"Expected":1.33,"Rank in p.value_classic":1026,"p.value_elim":0.03987,"p.value_classic":0.04057,"Genes":"ATP1B2,CAMK2D,SRI,TRDN"} {"Genesets":"GO:0014808","Term":"release of sequestered calcium ion into cytosol by sarcoplasmic reticulum","Annotated":24,"Significant":4,"Expected":1.33,"Rank in p.value_classic":1027,"p.value_elim":0.03987,"p.value_classic":0.04057,"Genes":"ANK2,CAMK2D,SRI,TRDN"} {"Genesets":"GO:0031664","Term":"regulation of lipopolysaccharide-mediated signaling pathway","Annotated":24,"Significant":4,"Expected":1.33,"Rank in p.value_classic":1028,"p.value_elim":0.03987,"p.value_classic":0.04057,"Genes":"ACOD1,CARD16,LILRA2,SCIMP"} {"Genesets":"GO:1903514","Term":"release of sequestered calcium ion into cytosol by endoplasmic reticulum","Annotated":24,"Significant":4,"Expected":1.33,"Rank in p.value_classic":1029,"p.value_elim":0.03987,"p.value_classic":0.04057,"Genes":"ANK2,CAMK2D,SRI,TRDN"} {"Genesets":"GO:0048514","Term":"blood vessel morphogenesis","Annotated":525,"Significant":46,"Expected":28.99,"Rank in p.value_classic":491,"p.value_elim":0.03998,"p.value_classic":0.00126,"Genes":"ADAM8,AGT,AMOT,BRCA1,C3,CD40,CDH5,CEACAM1,COMP,CX3CR1,CXCL10,CXCR3,CYSLTR1,DLL1,E2F2,E2F8,EDN1,ENPP2,EPAS1,EPHB3,GHRL,GLUL,HGF,HLA-G,IL12A,KLF4,LRP5,MIR503,NPR1,NRP1,PDE3B,PLCD3,PML,RAPGEF2,RNF213,S1PR1,SAT1,SGPL1,SOX17,STAT1,THBS2,TNFAIP2,TYMP,VEGFC,WARS1,ZC3H12A"} {"Genesets":"GO:0010212","Term":"response to ionizing radiation","Annotated":138,"Significant":13,"Expected":7.62,"Rank in p.value_classic":1032,"p.value_elim":0.03999,"p.value_classic":0.04151,"Genes":"BRCA1,CCL7,CXCL10,KARS1,PML,POLB,RAD54B,RAD54L,THBD,TICRR,TMEM109,VCAM1,XRCC2"} {"Genesets":"GO:0044000","Term":"movement in host","Annotated":157,"Significant":19,"Expected":8.67,"Rank in p.value_classic":474,"p.value_elim":0.04006,"p.value_classic":0.00105,"Genes":"CD74,CD80,CDK1,CHMP4C,CIITA,CXADR,DYNLT1,FCN1,HLA-DRB1,ICAM1,IFITM1,IFITM2,IFITM3,NRP1,SLAMF1,TPCN1,TRIM22,TRIM31,WWP1"} {"Genesets":"GO:1903522","Term":"regulation of blood circulation","Annotated":182,"Significant":24,"Expected":10.05,"Rank in p.value_classic":315,"p.value_elim":0.04013,"p.value_classic":0.00006,"Genes":"ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CD38,CXADR,CYSLTR1,EDN1,EPAS1,GCH1,GHRL,GJD3,HBEGF,HRH2,JAK2,KCNJ2,P2RX4,PDE4B,SCN4B,SPTBN4,SRI,TRDN,ZC3H12A"} {"Genesets":"GO:0032091","Term":"negative regulation of protein binding","Annotated":84,"Significant":9,"Expected":4.64,"Rank in p.value_classic":1034,"p.value_elim":0.04039,"p.value_classic":0.04161,"Genes":"AURKB,B2M,CARD16,DAB2,DTNBP1,IFIT2,LRRK2,RALB,XIRP1"} {"Genesets":"GO:0000278","Term":"mitotic cell cycle","Annotated":853,"Significant":73,"Expected":47.09,"Rank in p.value_classic":335,"p.value_elim":0.04058,"p.value_classic":0.00011,"Genes":"ABCB1,ANLN,APPL2,AURKB,BACH1,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CENPK,CHMP4C,CLSPN,CYLD,CYP1A1,DSCC1,DTL,DYNLT1,E2F1,E2F8,EDN1,EML4,ESCO2,FAM107A,GTSE1,HGF,IQGAP3,KIF11,KIF15,KIF18B,KLF4,LRP5,MAD2L1,MCM2,MCM4,MCM6,MKI67,MUC1,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,ORC1,OVOL1,PKMYT1,PML,PRC1,PSME1,PSME2,RRM2,SPC24,SPC25,STMN1,TACC2,TAL1,TICRR,UBD,XRCC2,ZWINT"} {"Genesets":"GO:0006301","Term":"postreplication repair","Annotated":35,"Significant":5,"Expected":1.93,"Rank in p.value_classic":1035,"p.value_elim":0.04078,"p.value_classic":0.04161,"Genes":"BRCA1,DTL,PARP10,PCLAF,POLE2"} {"Genesets":"GO:0001505","Term":"regulation of neurotransmitter levels","Annotated":167,"Significant":15,"Expected":9.22,"Rank in p.value_classic":1039,"p.value_elim":0.04139,"p.value_classic":0.04311,"Genes":"ASIC1,COLQ,DTNBP1,ERC2,GRIN3A,KCNJ10,LRRK2,MCTP2,P2RX7,PRRT2,SLC18A1,SLC6A12,STX11,SYNGR3,SYT1"} {"Genesets":"GO:1901699","Term":"cellular response to nitrogen compound","Annotated":550,"Significant":40,"Expected":30.37,"Rank in p.value_classic":1044,"p.value_elim":0.04173,"p.value_classic":0.04484,"Genes":"AGT,APPL2,BCL2L11,BRCA1,CASP4,CASP7,CASTOR1,CCNA2,CDC6,CEACAM1,COLEC12,CRHBP,CYSLTR2,DTNBP1,EDN1,GHRL,GNG2,HRH2,ICAM1,IFIH1,JAK2,JAK3,LRRK2,LYN,NOD2,P2RX4,P2RX7,PDE3B,PDE4B,PDK4,PID1,RALB,RAPGEF2,RIPK2,SESN3,SOCS1,STAT1,TGM2,VCAM1,XRN1"} {"Genesets":"GO:0015698","Term":"inorganic anion transport","Annotated":125,"Significant":12,"Expected":6.9,"Rank in p.value_classic":1040,"p.value_elim":0.04182,"p.value_classic":0.04333,"Genes":"ABCB1,ABCC11,ANKH,ANO4,APOL1,ATP8B1,CLIC5,GABRA3,SLC11A1,SLC12A3,SLC20A1,SLC37A1"} {"Genesets":"GO:0072678","Term":"T cell migration","Annotated":59,"Significant":7,"Expected":3.26,"Rank in p.value_classic":1037,"p.value_elim":0.04182,"p.value_classic":0.04289,"Genes":"ADAM8,CCL5,CXCL10,CXCL11,GPR183,ICAM1,S1PR1"} {"Genesets":"GO:0000082","Term":"G1/S transition of mitotic cell cycle","Annotated":211,"Significant":18,"Expected":11.65,"Rank in p.value_classic":1041,"p.value_elim":0.04227,"p.value_classic":0.04422,"Genes":"APPL2,BACH1,BTN2A2,CCNE2,CDC25A,CDC6,CDKN2C,CYP1A1,E2F1,FAM107A,GTSE1,IQGAP3,KLF4,MUC1,PML,PSME1,PSME2,RRM2"} {"Genesets":"GO:0015850","Term":"organic hydroxy compound transport","Annotated":182,"Significant":16,"Expected":10.05,"Rank in p.value_classic":1042,"p.value_elim":0.04252,"p.value_classic":0.04434,"Genes":"ABCC11,ADORA3,AGT,ATP8B1,CEACAM1,DAB2,DTNBP1,EEPD1,GHRL,GRAMD1B,OSBPL6,SLC18A1,SOAT1,SYT1,SYT6,TTC39B"} {"Genesets":"GO:1901653","Term":"cellular response to peptide","Annotated":301,"Significant":24,"Expected":16.62,"Rank in p.value_classic":1045,"p.value_elim":0.04266,"p.value_classic":0.04499,"Genes":"AGT,APPL2,BCL2L11,CASP4,CCNA2,CDC6,CEACAM1,CRHBP,CYSLTR2,EDN1,GHRL,ICAM1,JAK2,JAK3,LYN,NOD2,PDE3B,PDK4,PID1,RIPK2,SESN3,SOCS1,STAT1,VCAM1"} {"Genesets":"GO:0046887","Term":"positive regulation of hormone secretion","Annotated":85,"Significant":9,"Expected":4.69,"Rank in p.value_classic":1043,"p.value_elim":0.04307,"p.value_classic":0.04436,"Genes":"CD38,DAB2,EDN1,GHRL,GLUL,HCAR2,HLA-DRB1,JAK2,SRI"} {"Genesets":"GO:0035710","Term":"CD4-positive, alpha-beta T cell activation","Annotated":97,"Significant":19,"Expected":5.36,"Rank in p.value_classic":220,"p.value_elim":0.04365,"p.value_classic":1.2e-06,"Genes":"BCL6,CD274,CD28,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,JAK3,PTGER4,RELB,RIPK2,RSAD2,SLAMF6,SOCS1,TBX21,TNFSF18,ZC3H12A"} {"Genesets":"GO:1901987","Term":"regulation of cell cycle phase transition","Annotated":398,"Significant":42,"Expected":21.97,"Rank in p.value_classic":299,"p.value_elim":0.04375,"p.value_classic":0.00004,"Genes":"ANLN,APPL2,ATF5,AURKB,BIRC5,BRCA1,BTN2A2,BUB1B,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CHMP4C,CLSPN,CYP1A1,DTL,E2F1,FAM107A,FBXO6,GTSE1,HORMAD1,KLF4,MAD2L1,MIR503,MUC1,NDC80,NUF2,ORC1,OVOL1,PML,PSME1,PSME2,RRM2,SPC24,SPC25,TICRR,UBD,WDR76,ZWINT"} {"Genesets":"GO:0098771","Term":"inorganic ion homeostasis","Annotated":465,"Significant":45,"Expected":25.67,"Rank in p.value_classic":365,"p.value_elim":0.04383,"p.value_classic":0.00017,"Genes":"AGT,ANK2,ANKH,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,EPAS1,F2RL3,FAM20A,KCNJ10,KCNJ2,LRRK2,LYN,MCOLN2,MT2A,NPR1,P2RX7,PDK4,PML,RAB20,SCO2,SLAMF8,SLC11A1,SLC12A3,SLC25A28,SLC31A2,SNX10,SRI,STEAP4,TGM2,TPCN1,TRDN"} {"Genesets":"GO:0051092","Term":"positive regulation of NF-kappaB transcription factor activity","Annotated":140,"Significant":13,"Expected":7.73,"Rank in p.value_classic":1046,"p.value_elim":0.04408,"p.value_classic":0.04574,"Genes":"ADAM8,AGT,AIM2,CARD16,CD40,CX3CR1,EDA,NOD2,RHEBL1,RIPK2,TNFRSF11A,TNFSF18,TRIM22"} {"Genesets":"GO:0007260","Term":"tyrosine phosphorylation of STAT protein","Annotated":58,"Significant":13,"Expected":3.2,"Rank in p.value_classic":261,"p.value_elim":0.04453,"p.value_classic":0.00001,"Genes":"CCL5,CD40,IL12A,IL15,IL22RA2,IL31RA,JAK2,JAK3,LYN,OSM,PARP14,SOCS1,TNFSF18"} {"Genesets":"GO:0071417","Term":"cellular response to organonitrogen compound","Annotated":505,"Significant":37,"Expected":27.88,"Rank in p.value_classic":1080,"p.value_elim":0.04455,"p.value_classic":0.04768,"Genes":"AGT,APPL2,BCL2L11,BRCA1,CASP4,CASP7,CASTOR1,CCNA2,CDC6,CEACAM1,CRHBP,CYSLTR2,DTNBP1,EDN1,GHRL,GNG2,HRH2,ICAM1,JAK2,JAK3,LRRK2,LYN,NOD2,P2RX4,P2RX7,PDE3B,PDE4B,PDK4,PID1,RAPGEF2,RIPK2,SESN3,SOCS1,STAT1,TGM2,VCAM1,XRN1"}