NEWS

---

GRmetrics 1.3.3

• Renamed column "GR" to "GRvalue" for GR value table to match other code.
• Fixed erroneous error message in division rate GR value calculation

GRmetrics 1.3.2

• Renamed some curve parameters for the relative cell count curve
• changed "IC" to "rel_cell".
• Changed GRdrawDRC function parameter option for dose response curves based on relative cell counts from 'metric = "IC"' to 'metric = "rel_cell"'.
• Changed GRinf (and Einf) value to the minimum of the mean GR values (relative cell count) at the two highest concentrations tested for the case of horizontal line fits (same as GRmax).
• Changed GRmax (and Emax) so that in the case of averaging over multiple conditions, the value taken is the minimum of the mean of GR values (relative cell count) at the two highest concentrations instead of the absolute minimum GR value at these concentrations.
• "duration" column in input changed to "treatment_duration" to match the nomenclature in other code.
• Added calculation of GR values from division rates for Case "C"

GRmetrics 1.3.1

• Added calculation of GR values from division rates for Case "A"
• now accepts columns "duration" and "division_time" instead of "cell_count__time0"
• Added a few parameters to calculation
• "control_cell_doublings" is the number of cell doublings that occur in the control population over the assay, calculated either from initial and final cell counts or given division rate and time of assay.
• "concentration_points" is the number of different concentrations used in an experiment