Fit-Hi-C is a tool for assigning statistical confidence estimates to intra-chromosomal contact maps produced by genome-wide genome architecture assays such as Hi-C. Compared to Python original, Fit-Hi-C R port has the following advantages:
Fit-Hi-C R package is more efficient than Python original by re-writting some logic in C/C++
Fit-Hi-C R package is easy to use for those familiar with R language without additional configuration