Package: DriverNet Type: Package Title: Drivernet: uncovering somatic driver mutations modulating transcriptional networks in cancer Version: 1.53.0 Date: 2012-03-21 Author: Ali Bashashati, Reza Haffari, Jiarui Ding, Gavin Ha, Kenneth Liu, Jamie Rosner and Sohrab Shah Maintainer: Jiarui Ding Description: DriverNet is a package to predict functional important driver genes in cancer by integrating genome data (mutation and copy number variation data) and transcriptome data (gene expression data). The different kinds of data are combined by an influence graph, which is a gene-gene interaction network deduced from pathway data. A greedy algorithm is used to find the possible driver genes, which may mutated in a larger number of patients and these mutations will push the gene expression values of the connected genes to some extreme values. License: GPL-3 LazyLoad: yes Depends: R (>= 2.10), methods biocViews: Network Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:37:07 UTC RemoteUrl: https://github.com/bioc/DriverNet RemoteRef: HEAD RemoteSha: 31b204b44392329ded43a2b70707410254e3ae58 NeedsCompilation: no Packaged: 2026-07-04 23:03:28 UTC; root