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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "Dino" in publications use:'
type: software
license: GPL-3.0-only
title: 'Dino: Normalization of Single-Cell mRNA Sequencing Data'
version: 1.11.0
doi: 10.1093/bioinformatics/btab450
identifiers:
- type: doi
  value: 10.32614/CRAN.package.Dino
abstract: Dino normalizes single-cell, mRNA sequencing data to correct for technical
  variation, particularly sequencing depth, prior to downstream analysis. The approach
  produces a matrix of corrected expression for which the dependency between sequencing
  depth and the full distribution of normalized expression; many existing methods
  aim to remove only the dependency between sequencing depth and the mean of the normalized
  expression. This is particuarly useful in the context of highly sparse datasets
  such as those produced by 10X genomics and other uninque molecular identifier (UMI)
  based microfluidics protocols for which the depth-dependent proportion of zeros
  in the raw expression data can otherwise present a challenge.
authors:
- family-names: Brown
  given-names: Jared
  email: brownj@ds.dfci.harvard.edu
  orcid: https://orcid.org/0000-0002-9151-4386
preferred-citation:
  type: article
  title: Normalization by distributional resampling of high throughput single-cell
    RNA-sequencing data.
  authors:
  - family-names: Brown
    given-names: Jared
    email: brownj@ds.dfci.harvard.edu
    orcid: https://orcid.org/0000-0002-9151-4386
  - family-names: Ni
    given-names: Zijian
  - family-names: Mohanty
    given-names: Chitrasen
  - family-names: Bacher
    given-names: Rhonda
  - family-names: Kendziorski
    given-names: Christina
  journal: Bioinformatics.
  year: '2021'
  doi: 10.1093/bioinformatics/btab450
repository: https://bioc.r-universe.dev
repository-code: https://github.com/JBrownBiostat/Dino
commit: c9c0971bd4690c573af7161f763ebe556a02983c
url: https://github.com/JBrownBiostat/Dino
contact:
- family-names: Brown
  given-names: Jared
  email: brownj@ds.dfci.harvard.edu
  orcid: https://orcid.org/0000-0002-9151-4386