Package: DenoIST Title: DenoIST: Denoising Image-based Spatial Transcriptomics data Version: 1.1.0 Authors@R: c( person("Aaron", "Kwok", , "akwok@svi.edu.au", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-7831-4198")), person("Heejung","Shim", role=c("aut")), person("Davis","McCarthy", role=c("aut"))) biocViews: Software, Preprocessing, Spatial, GeneExpression, SingleCell, Transcriptomics Description: DenoIST identifies and removes contamination in Image-based Spatial Transcriptomics data, using a transposed poisson mixture model with local neighbourhood offsets to infer genes that are likely to be due to neighbourhood contamination rather than endogenous expression. License: MIT + file LICENSE Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 URL: https://github.com/aaronkwc/DenoIST BugReports: https://github.com/aaronkwc/DenoIST/issues Imports: flexmix, hexbin, pbapply, sparseMatrixStats, SpatialExperiment, stats, SummarizedExperiment, parallel, Matrix, dbscan, methods Suggests: BiocStyle, knitr, rmarkdown, testthat, ggplot2, patchwork VignetteBuilder: knitr Config/pak/sysreqs: libmagick++-dev gsfonts libicu-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:06:20 UTC RemoteUrl: https://github.com/bioc/DenoIST RemoteRef: HEAD RemoteSha: 35bfd0d4b063c8739a6e981edee07bb2932f5948 NeedsCompilation: no Packaged: 2026-07-09 10:07:35 UTC; root Author: Aaron Kwok [aut, cre] (ORCID: ), Heejung Shim [aut], Davis McCarthy [aut] Maintainer: Aaron Kwok Depends: R (>= 3.5.0)