Package: DRIMSeq Type: Package Title: Differential transcript usage and tuQTL analyses with Dirichlet-multinomial model in RNA-seq Version: 1.41.4 Date: 2026-10-29 Authors@R: c(person(given = "Malgorzata", family = "Nowicka", role = c("aut"), email = "gosia.nowicka.uzh@gmail.com"), person("Mark D.", "Robinson", role = c("cre"), email = "mark.robinson@mls.uzh.ch", comment = c(ORCID = "0000-0002-3048-5518"))) Description: The package provides two frameworks. One for the differential transcript usage analysis between different conditions and one for the tuQTL analysis. Both are based on modeling the counts of genomic features (i.e., transcripts) with the Dirichlet-multinomial distribution. The package also makes available functions for visualization and exploration of the data and results. biocViews: ImmunoOncology, SNP, AlternativeSplicing, DifferentialSplicing, Genetics, RNASeq, Sequencing, WorkflowStep, MultipleComparison, GeneExpression, DifferentialExpression License: GPL (>= 3) Depends: R (>= 3.4.0) Imports: utils, stats, MASS, GenomicRanges, IRanges, S4Vectors, BiocGenerics, methods, BiocParallel, limma, edgeR, ggplot2, reshape2 Suggests: grid, BiocStyle, knitr, testthat ByteCompile: false VignetteBuilder: knitr Collate: 'DRIMSeq.R' 'aaa.R' 'class_show_utils.R' 'class_MatrixList.R' 'class_dmDSdata.R' 'class_dmDSprecision.R' 'class_dmDSfit.R' 'class_dmDStest.R' 'class_dmSQTLdata.R' 'class_dmSQTLprecision.R' 'class_dmSQTLfit.R' 'class_dmSQTLtest.R' 'dmDS_CRadjustment.R' 'dmDS_estimateCommonPrecision.R' 'dmDS_estimateTagwisePrecision.R' 'dmDS_filter.R' 'dmDS_fit.R' 'dmDS_profileLik.R' 'dmSQTL_CRadjustment.R' 'dmSQTL_estimateCommonPrecision.R' 'dmSQTL_estimateTagwisePrecision.R' 'dmSQTL_filter.R' 'dmSQTL_fit.R' 'dmSQTL_permutations.R' 'dmSQTL_profileLik.R' 'dm_CRadjustmentManyGroups.R' 'dm_CRadjustmentOneGroup.R' 'dm_CRadjustmentRegression.R' 'dm_LRT.R' 'dm_core_Hessian.R' 'dm_core_colorb.R' 'dm_core_deviance.R' 'dm_core_lik.R' 'dm_core_score.R' 'dm_estimateMeanExpression.R' 'dm_fitManyGroups.R' 'dm_fitOneGroup.R' 'dm_fitRegression.R' 'dm_plotData.R' 'dm_plotPrecision.R' 'dm_plotProportions.R' 'dm_plotPvalues.R' 'dm_profileLikModeration.R' Config/roxygen2/version: 8.1.0 Config/pak/sysreqs: libicu-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-10-29 17:56:34 UTC RemoteUrl: https://github.com/bioc/DRIMSeq RemoteRef: HEAD RemoteSha: d7a601b2e9a568e89c3e2ed0fe1207b3456ff075 NeedsCompilation: no Packaged: 2026-10-30 02:13:41 UTC; root Author: Malgorzata Nowicka [aut], Mark D. Robinson [cre] (ORCID: ) Maintainer: Mark D. Robinson