Package: DOSE Type: Package Title: Disease Ontology Semantic and Enrichment analysis Version: 4.7.3 Authors@R: c( person(given = "Guangchuang", family = "Yu", email = "guangchuangyu@gmail.com", role = c("aut", "cre")), person(given = "Li-Gen", family = "Wang", email = "reeganwang020@gmail.com", role = "ctb"), person(given = "Vladislav", family = "Petyuk", email = "petyuk@gmail.com", role = "ctb"), person(given = "Giovanni", family = "Dall'Olio", email = "giovanni.dallolio@upf.edu", role = "ctb")) Maintainer: Guangchuang Yu Description: Provides ontology-aware methods for disease and phenotype knowledge mining. DOSE supports semantic similarity analysis of disease and phenotype ontology terms, genes, and gene clusters using methods including Resnik, Schlicker, Jiang, Lin, and Wang. It also provides over-representation analysis and gene set enrichment analysis for interpreting gene vectors and ranked gene lists in disease, phenotype, and cancer contexts. Depends: R (>= 3.5.0) Imports: AnnotationDbi, enrichit (>= 0.2.2), ggplot2, GOSemSim (>= 2.39.2), gson (>= 0.0.5), memoise, methods, reshape2, utils, yulab.utils (> 0.2.2) Suggests: aisdk, clusterProfiler, knitr, org.Hs.eg.db, org.Mm.eg.db, quarto, testthat VignetteBuilder: quarto ByteCompile: true License: Artistic-2.0 Encoding: UTF-8 URL: https://yulab-smu.top/contribution-knowledge-mining/ BugReports: https://github.com/GuangchuangYu/DOSE/issues Packaged: 2026-09-24 19:33:41 UTC; root biocViews: Annotation, Visualization, MultipleComparison, GeneSetEnrichment, Pathways, Software Config/roxygen2/version: 8.1.0 Config/pak/sysreqs: cmake make libicu-dev libpng-dev libuv1-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-09-24 01:21:11 UTC RemoteUrl: https://github.com/bioc/DOSE RemoteRef: HEAD RemoteSha: 5846d72fe047f1de66d506a21c117d400e4a3ef8 NeedsCompilation: no Author: Guangchuang Yu [aut, cre], Li-Gen Wang [ctb], Vladislav Petyuk [ctb], Giovanni Dall'Olio [ctb]