Package: DMRScan Title: Detection of Differentially Methylated Regions Version: 1.35.0 Authors@R: c( person("CM", "Page", email = "page.ntnu@gmail.com", role = c("aut","cre")), person("L", "Vos", email = "Linda.Vos@Kreftregisteret.no", role = "aut"), person("TB", "Rounge", email = "", role = "ctb"), person("HF", "Harbo", email = "", role = "ths"), person("BK", "Andreassen", email = "Bettina.Kulle.Andreassen@Kreftregisteret.no", role = "aut")) Description: This package detects significant differentially methylated regions (for both qualitative and quantitative traits), using a scan statistic with underlying Poisson heuristics. The scan statistic will depend on a sequence of window sizes (# of CpGs within each window) and on a threshold for each window size. This threshold can be calculated by three different means: i) analytically using Siegmund et.al (2012) solution (preferred), ii) an important sampling as suggested by Zhang (2008), and a iii) full MCMC modeling of the data, choosing between a number of different options for modeling the dependency between each CpG. biocViews: Software, Technology, Sequencing, WholeGenome Depends: R (>= 3.6.0) Imports: Matrix, MASS, RcppRoll,GenomicRanges, IRanges, Seqinfo, methods, mvtnorm, stats, parallel License: GPL-3 LazyData: true Author: Christian M Page [aut, cre], Linda Vos [aut], Trine B Rounge [ctb, dtc], Hanne F Harbo [ths], Bettina K Andreassen [aut] Maintainer: Christian M Page RoxygenNote: 6.1.1 Suggests: knitr, rmarkdown, BiocStyle, BiocManager VignetteBuilder: knitr URL: https://github.com/christpa/DMRScan BugReports: https://github.com/christpa/DMRScan/issues PackageStatus: Active Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:44:58 UTC RemoteUrl: https://github.com/bioc/DMRScan RemoteRef: HEAD RemoteSha: 63e5f092d65ea40828a6105273d49458a29f94e6 NeedsCompilation: no Packaged: 2026-07-14 06:09:34 UTC; root