Package: DEqMS Version: 1.31.0 Date: 2025/05/10 Title: a tool to perform statistical analysis of differential protein expression for quantitative proteomics data. Author: Yafeng Zhu Maintainer: Yafeng Zhu Depends: R(>= 3.5),graphics,stats,ggplot2,matrixStats,dplyr,limma(>= 3.34) Suggests: BiocStyle,knitr,rmarkdown,markdown,plyr,reshape2,utils,ggrepel,ExperimentHub,LSD LazyLoad: yes Description: DEqMS is developped on top of Limma. However, Limma assumes same prior variance for all genes. In proteomics, the accuracy of protein abundance estimates varies by the number of peptides/PSMs quantified in both label-free and labelled data. Proteins quantification by multiple peptides or PSMs are more accurate. DEqMS package is able to estimate different prior variances for proteins quantified by different number of PSMs/peptides, therefore acchieving better accuracy. The package can be applied to analyze both label-free and labelled proteomics data. License: LGPL biocViews: ImmunoOncology, Proteomics, MassSpectrometry, Preprocessing, DifferentialExpression, MultipleComparison,Normalization,Bayesian,ExperimentHubSoftware VignetteBuilder: knitr Packaged: 2026-07-05 01:52:29 UTC; root BugReports: https://github.com/yafeng/DEqMS/issues Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:48:40 UTC RemoteUrl: https://github.com/bioc/DEqMS RemoteRef: HEAD RemoteSha: fcec1ed7d05159dd822367a3adeab34193e32e8c NeedsCompilation: no