Package: CoSIA
Type: Package
Title: An Investigation Across Different Species and Tissues
Version: 1.13.2
Authors@R: 
  c(person(given = "Anisha",
           family = "Haldar",
           role = "aut",
           comment = c(ORCID = "0000-0002-1395-9793")),
    person(given = c("Vishal", "H."),
           family = "Oza",
           role = "aut",
           comment = c(ORCID = "0000-0001-6990-0267")),
    person(given = c("Amanda", "D."),
           family = "Clark",
           role = c("aut"),
           email = "clarkaduab@gmail.com",
           comment = c(ORCID = "0000-0002-1186-3114")),
    person(given = c("Anthony", "B."),
           family = "Crumley",
           role = c("cre", "aut"),
           email = "acrumley@uab.edu",
           comment = c(ORCID = "0009-0004-7347-4722")),
    person(given = c("Nathaniel", "S."),
           family = "DeVoss",
           role = "aut",
           comment = c(ORCID = "0000-0003-0465-2770")),
    person(given = c("Brittany", "N."),
           family = "Lasseigne",
           role = c("aut"),
           comment = c(ORCID = "0000-0002-1642-8904")))
Description: Cross-Species Investigation and Analysis (CoSIA) is a
        package that provides researchers with an alternative
        methodology for comparing across species and tissues using
        normal wild-type RNA-Seq Gene Expression data from Bgee. Using
        RNA-Seq Gene Expression data, CoSIA provides multiple
        visualization tools to explore the transcriptome diversity and
        variation across genes, tissues, and species. CoSIA uses the
        Coefficient of Variation and Shannon Entropy and Specificity to
        calculate transcriptome diversity and variation. CoSIA also
        provides additional conversion tools and utilities to provide a
        streamlined methodology for cross-species comparison.
License: MIT + file LICENSE
Encoding: UTF-8
Depends: R (>= 4.3.0), methods (>= 4.3.0), ExperimentHub (>= 2.7.0)
Imports: dplyr (>= 1.0.7), magrittr (>= 2.0.1), RColorBrewer (>=
        1.1-2), tidyr (>= 1.2.0), plotly (>= 4.10.0), stringr (>=
        1.4.0), ggplot2 (>= 3.3.5), tibble (>= 3.1.7), org.Hs.eg.db (>=
        3.12.0), org.Mm.eg.db (>= 3.12.0), org.Dr.eg.db (>= 3.12.0),
        org.Ce.eg.db (>= 3.12.0), org.Dm.eg.db (>= 3.12.0),
        org.Rn.eg.db (>= 3.12.0), AnnotationDbi (>= 1.52.0), biomaRt
        (>= 2.46.3), homologene (>= 1.4.68.19), annotationTools (>=
        1.64.0), readr (>= 2.1.1), tidyselect (>= 1.1.2), stats (>=
        4.1.2)
RoxygenNote: 7.3.3
Suggests: BiocStyle (>= 2.22.0), tidyverse (>= 1.3.1), knitr (>= 1.42),
        rmarkdown (>= 2.20), testthat (>= 3.1.6), qpdf (>= 1.3.0)
biocViews: Software, BiologicalQuestion, GeneExpression,
        MultipleComparison, ThirdPartyClient, DataImport, GUI
BugReports: https://github.com/lasseignelab/CoSIA/issues
URL: https://www.lasseigne.org/
VignetteBuilder: knitr
Config/testthat/edition: 3
Config/pak/sysreqs: cmake make libicu-dev libpng-dev libuv1-dev
        libxml2-dev libssl-dev libx11-dev zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-06-30 20:31:05 UTC
RemoteUrl: https://github.com/bioc/CoSIA
RemoteRef: HEAD
RemoteSha: b1c2605a9c98d99fd2d85e07498ef4a0b78c2e10
NeedsCompilation: no
Packaged: 2026-06-30 22:40:21 UTC; root
Author: Anisha Haldar [aut] (ORCID: <https://orcid.org/0000-0002-1395-9793>),
  Vishal H. Oza [aut] (ORCID: <https://orcid.org/0000-0001-6990-0267>),
  Amanda D. Clark [aut] (ORCID: <https://orcid.org/0000-0002-1186-3114>),
  Anthony B. Crumley [cre, aut] (ORCID:
    <https://orcid.org/0009-0004-7347-4722>),
  Nathaniel S. DeVoss [aut] (ORCID:
    <https://orcid.org/0000-0003-0465-2770>),
  Brittany N. Lasseigne [aut] (ORCID:
    <https://orcid.org/0000-0002-1642-8904>)
Maintainer: Anthony B. Crumley <acrumley@uab.edu>