Package: ChIPseeker Type: Package Title: ChIPseeker for ChIP peak Annotation, Comparison, and Visualization Version: 1.49.0 Authors@R: c( person(given = "Guangchuang", family = "Yu", email = "guangchuangyu@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-6485-8781")), person(given = "Ming", family = "Li", email = "limiang929@gmail.com", role = "ctb"), person(given = "Qianwen", family = "Wang", email = "treywea@gmail.com", role = "ctb"), person(given = "Yun", family = "Yan", email = "youryanyun@gmail.com", role = "ctb"), person(given = "Hervé", family = "Pagès", email = "hpages.on.github@gmail.com", role = "ctb"), person(given = "Michael", family = "Kluge", email = "michael.kluge@bio.ifi.lmu.de", role = "ctb"), person(given = "Thomas", family = "Schwarzl", email = "schwarzl@embl.de", role = "ctb"), person(given = "Zhougeng", family = "Xu", email = "xuzhougeng@163.com", role = "ctb"), person(given = "Chun-Hui", family = "Gao", email="gaospecial@gmail.com", role = "ctb", comment=c(ORCID = "0000-0002-1445-7939")) ) Maintainer: Guangchuang Yu Description: This package implements functions to retrieve the nearest genes around the peak, annotate genomic region of the peak, statstical methods for estimate the significance of overlap among ChIP peak data sets, and incorporate GEO database for user to compare the own dataset with those deposited in database. The comparison can be used to infer cooperative regulation and thus can be used to generate hypotheses. Several visualization functions are implemented to summarize the coverage of the peak experiment, average profile and heatmap of peaks binding to TSS regions, genomic annotation, distance to TSS, and overlap of peaks or genes. Depends: R (>= 4.1.0) Imports: AnnotationDbi, aplot, BiocGenerics, boot, dplyr, enrichplot, IRanges, GenomeInfoDb, GenomicRanges, GenomicFeatures, ggplot2, gplots, graphics, grDevices, gtools, magrittr, methods, plotrix, parallel, RColorBrewer, rlang, rtracklayer, S4Vectors, scales, stats, tibble, TxDb.Hsapiens.UCSC.hg19.knownGene, utils, yulab.utils (>= 0.2.0) Suggests: clusterProfiler, ggimage, ggplotify, ggupset, ggVennDiagram, knitr, org.Hs.eg.db, prettydoc, ReactomePA, rmarkdown, testthat, TxDb.Hsapiens.UCSC.hg38.knownGene Remotes: GuangchuangYu/enrichplot URL: https://yulab-smu.top/contribution-knowledge-mining/ BugReports: https://github.com/YuLab-SMU/ChIPseeker/issues Encoding: UTF-8 VignetteBuilder: knitr ByteCompile: true License: Artistic-2.0 biocViews: Annotation, ChIPSeq, Software, Visualization, MultipleComparison RoxygenNote: 7.3.3 Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev libglpk-dev make libbz2-dev libicu-dev liblzma-dev libpng-dev libuv1-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:39:06 UTC RemoteUrl: https://github.com/bioc/ChIPseeker RemoteRef: HEAD RemoteSha: f0e31113d0c2879cf2978969077822318c4d84e8 NeedsCompilation: no Packaged: 2026-05-29 08:42:02 UTC; root Author: Guangchuang Yu [aut, cre] (ORCID: ), Ming Li [ctb], Qianwen Wang [ctb], Yun Yan [ctb], Hervé Pagès [ctb], Michael Kluge [ctb], Thomas Schwarzl [ctb], Zhougeng Xu [ctb], Chun-Hui Gao [ctb] (ORCID: )