Package: CatsCradle Title: This package provides methods for analysing spatial transcriptomics data and for discovering gene clusters Version: 1.7.1 Authors@R: c(person(given = "Anna", family = "Laddach", role = c("aut"), email = "anna.laddach@crick.ac.uk", comment = c(ORCID = "0000-0001-5552-6534")), person(given = "Michael", family = "Shapiro", role = c("aut","cre"), email = "michael.shapiro@crick.ac.uk", comment = c(ORCID = "0000-0002-2769-9320"))) Description: This package addresses two broad areas. It allows for in-depth analysis of spatial transcriptomic data by identifying tissue neighbourhoods. These are contiguous regions of tissue surrounding individual cells. 'CatsCradle' allows for the categorisation of neighbourhoods by the cell types contained in them and the genes expressed in them. In particular, it produces Seurat objects whose individual elements are neighbourhoods rather than cells. In addition, it enables the categorisation and annotation of genes by producing Seurat objects whose elements are genes. License: MIT + file LICENSE Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Imports: Seurat (>= 5.0.1), ggplot2, networkD3, stringr, pracma, reshape2, rdist, igraph, geometry, Rfast, data.table, abind, pheatmap, EBImage, S4Vectors, SeuratObject, SingleCellExperiment, SpatialExperiment, Matrix, methods, SummarizedExperiment, msigdbr Suggests: fossil, interp, knitr, BiocStyle, tictoc Depends: R (>= 4.4.0) LazyData: false VignetteBuilder: knitr BugReports: https://github.com/AnnaLaddach/CatsCradle/issues URL: https://github.com/AnnaLaddach/CatsCradle biocViews: BiologicalQuestion, StatisticalMethod, GeneExpression, SingleCell, Transcriptomics, Spatial NeedsCompilation: no Packaged: 2026-07-02 15:22:15 UTC; root Config/pak/sysreqs: cmake libfftw3-dev libglpk-dev make libmagick++-dev gsfonts libicu-dev libjpeg-dev libpng-dev libtiff-dev libuv1-dev libxml2-dev libssl-dev python3 zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-07-02 08:50:35 UTC RemoteUrl: https://github.com/bioc/CatsCradle RemoteRef: HEAD RemoteSha: 7313e146c9ca7fdc79b7a8812e7e0429b94f5ac8 Author: Anna Laddach [aut] (ORCID: ), Michael Shapiro [aut, cre] (ORCID: ) Maintainer: Michael Shapiro