Package: CONSTANd
Type: Package
Title: Data normalization by matrix raking
Version: 1.21.0
Date: 2020-10-30
Authors@R: c(person("Joris", "Van Houtven", email="joris.vanhoutven@uhasselt.be", role=c("aut","trl")),
			 person("Geert Jan", "Bex", email="geertjan.bex@uhasselt.be", role=c("trl")),
			 person("Dirk", "Valkenborg", email="dirk.valkenborg@uhasselt.be", role=c("aut", "cre")))
Description: Normalizes a data matrix `data` by raking (using the RAS
        method by Bacharach, see references) the Nrows by Ncols matrix
        such that the row means and column means equal 1. The result is
        a normalized data matrix `K=RAS`, a product of row mulipliers
        `R` and column multipliers `S` with the original matrix `A`.
        Missing information needs to be presented as `NA` values and
        not as zero values, because CONSTANd is able to ignore missing
        values when calculating the mean. Using CONSTANd normalization
        allows for the direct comparison of values between samples
        within the same and even across different CONSTANd-normalized
        data matrices.
License: file LICENSE
Encoding: UTF-8
biocViews: MassSpectrometry, Cheminformatics, Normalization,
        Preprocessing, DifferentialExpression, Genetics,
        Transcriptomics, Proteomics
NeedsCompilation: no
Depends: R (>= 4.1)
Suggests: BiocStyle, knitr, rmarkdown, tidyr, ggplot2, gridExtra,
        magick, Cairo, limma
SystemRequirements:
BugReports: https://github.com/PDiracDelta/CONSTANd/issues
URL: qcquan.net/constand
VignetteBuilder: knitr
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:54:46 UTC
RemoteUrl: https://github.com/bioc/CONSTANd
RemoteRef: HEAD
RemoteSha: 6cdef6e9cc86c3577570e8bfdb37045a52693c91
Packaged: 2026-07-04 12:16:23 UTC; root
Author: Joris Van Houtven [aut, trl],
  Geert Jan Bex [trl],
  Dirk Valkenborg [aut, cre]
Maintainer: Dirk Valkenborg <dirk.valkenborg@uhasselt.be>