NEWS
CLAMP 0.99.0
New features
- Initial Bioconductor submission.
- Implements prior-informed latent variable decomposition for gene expression.
- Supports file-backed matrices (
bigstatsr::FBM) for large datasets.
- Added CPM, z-score, and filtering functions for preprocessing.
- Projection of new datasets into pre-trained models.
- Vignettes with example workflows and detailed documentation.
Improvements
- Optimized in-place operations for large matrices.
- Added cross-validation utilities and adaptive sparsity support.
- Roxygen2 documentation for all exported functions.
Bug fixes
- Fixed edge case in CPM normalization for zero-count columns.
- Corrected NA handling in preprocessing.