Package: CIMICE Type: Package Title: CIMICE-R: (Markov) Chain Method to Inferr Cancer Evolution Version: 1.21.0 Authors@R: c( person("Nicolò", "Rossi", role=c("aut", "cre"), email="olocin.issor@gmail.com", comment = c("Lab. of Computational Biology and Bioinformatics, Department of Mathematics, Computer Science and Physics, University of Udine",ORCID = "0000-0002-6353-7396")) ) Description: CIMICE is a tool in the field of tumor phylogenetics and its goal is to build a Markov Chain (called Cancer Progression Markov Chain, CPMC) in order to model tumor subtypes evolution. The input of CIMICE is a Mutational Matrix, so a boolean matrix representing altered genes in a collection of samples. These samples are assumed to be obtained with single-cell DNA analysis techniques and the tool is specifically written to use the peculiarities of this data for the CMPC construction. License: Artistic-2.0 Encoding: UTF-8 Imports: dplyr, ggplot2, glue, tidyr, igraph, networkD3, visNetwork, ggcorrplot, purrr, ggraph, stats, utils, maftools, assertthat, tidygraph, expm, Matrix RoxygenNote: 7.1.2 VignetteBuilder: knitr Suggests: BiocStyle, knitr, rmarkdown, testthat, webshot biocViews: Software, BiologicalQuestion, NetworkInference, ResearchField, Phylogenetics, StatisticalMethod, GraphAndNetwork, Technology, SingleCell BugReports: https://github.com/redsnic/CIMICE/issues URL: https://github.com/redsnic/CIMICE BiocType: Software Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev libglpk-dev make libbz2-dev libicu-dev liblzma-dev libuv1-dev libxml2-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:55:26 UTC RemoteUrl: https://github.com/bioc/CIMICE RemoteRef: HEAD RemoteSha: 57344c846b0a08505194acdb7fd2b6f0589d7bc8 NeedsCompilation: no Packaged: 2026-07-03 23:40:06 UTC; root Author: Nicolò Rossi [aut, cre] (Lab. of Computational Biology and Bioinformatics, Department of Mathematics, Computer Science and Physics, University of Udine, ORCID: ) Maintainer: Nicolò Rossi