Package: CDI Version: 1.11.0 Date: 2026-03-15 Title: Clustering Deviation Index (CDI) Description: Single-cell RNA-sequencing (scRNA-seq) is widely used to explore cellular variation. The analysis of scRNA-seq data often starts from clustering cells into subpopulations. This initial step has a high impact on downstream analyses, and hence it is important to be accurate. However, there have not been unsupervised metric designed for scRNA-seq to evaluate clustering performance. Hence, we propose clustering deviation index (CDI), an unsupervised metric based on the modeling of scRNA-seq UMI counts to evaluate clustering of cells. Authors@R: c(person("Jiyuan", "Fang", email = "jfanglovestats@gmail.com", role = c("cre", "aut"), comment=c(ORCID="0000-0002-5004-4138")), person("Jichun", "Xie", email = "jichun.xie@duke.edu", role = c("ctb")), person("Cliburn", "Chan", email = "cliburn.chan@duke.edu", role = c("ctb")), person("Kouros", "Owzar", email = "kouros.owzar@duke.edu", role = c("ctb")), person("Liuyang", "Wang", email = "liuyang.wang@duke.edu", role = c("ctb")), person("Diyuan", "Qin", email = "diyuan.qin@duke.edu", role = c("ctb")), person("Qi-Jing", "Li", email = "qi-jing.li@duke.edu", role = c("ctb"))) biocViews: SingleCell, Software, Clustering, Visualization, Sequencing, RNASeq, CellBasedAssays URL: https://github.com/jichunxie/CDI BugReports: https://github.com/jichunxie/CDI/issues Imports: matrixStats, SeuratObject, Seurat, stats, BiocParallel, ggplot2, reshape2, grDevices, ggsci, SingleCellExperiment, SummarizedExperiment, methods RoxygenNote: 7.2.3 Depends: R(>= 3.6) Suggests: knitr, rmarkdown, RUnit, BiocGenerics, magick, BiocStyle VignetteBuilder: knitr License: GPL-3 + file LICENSE Encoding: UTF-8 Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev python3 zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:01:09 UTC RemoteUrl: https://github.com/bioc/CDI RemoteRef: HEAD RemoteSha: 191ae443191765e67e31d38ed1a0da1df314157c NeedsCompilation: no Packaged: 2026-07-18 04:53:09 UTC; root Author: Jiyuan Fang [cre, aut] (ORCID: ), Jichun Xie [ctb], Cliburn Chan [ctb], Kouros Owzar [ctb], Liuyang Wang [ctb], Diyuan Qin [ctb], Qi-Jing Li [ctb] Maintainer: Jiyuan Fang