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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "CARDspa" in publications use:'
type: software
license: GPL-3.0-only
title: 'CARDspa: Spatially Informed Cell Type Deconvolution for Spatial Transcriptomics'
version: 0.99.5
doi: 10.1038/s41587-022-01273-7
abstract: CARD is a reference-based deconvolution method that estimates cell type
  composition in spatial transcriptomics based on cell type specific expression information
  obtained from a reference scRNA-seq data. A key feature of CARD is its ability to
  accommodate spatial correlation in the cell type composition across tissue locations,
  enabling accurate and spatially informed cell type deconvolution as well as refined
  spatial map construction. CARD relies on an efficient optimization algorithm for
  constrained maximum likelihood estimation and is scalable to spatial transcriptomics
  with tens of thousands of spatial locations and tens of thousands of genes.
authors:
- family-names: Ma
  given-names: Ying
  email: ying_ma@brown.edu
- family-names: Fu
  given-names: Jing
  email: jing_fu@brown.edu
preferred-citation:
  type: article
  title: Spatially informed cell-type deconvolution for spatial transcriptomics
  authors:
  - family-names: Ma
    given-names: Ying
    email: ying_ma@brown.edu
  - family-names: Zhou
    given-names: Xiang
  journal: Nat Biotechnol
  year: '2022'
  volume: '40'
  doi: 10.1038/s41587-022-01273-7
  start: 1349-1359
repository: https://bioc.r-universe.dev
repository-code: https://github.com/YMa-lab/CARDspa
commit: 31984e0712943e92bd19b98d696fc46ecc2b8a0a
url: https://github.com/YMa-lab/CARDspa
date-released: '2025-02-06'
contact:
- family-names: Fu
  given-names: Jing
  email: jing_fu@brown.edu