Package 'BridgeDbR'

Title: Code for using BridgeDb identifier mapping framework from within R
Description: Use BridgeDb functions and load identifier mapping databases in R. It uses GitHub, Zenodo, and Figshare if you use this package to download identifier mappings files.
Authors: Christ Leemans <[email protected]>, Egon Willighagen <[email protected]>, Denise Slenter, Anwesha Bohler <[email protected]>, Lars Eijssen <[email protected]>, Tooba Abbassi-Daloii
Maintainer: Egon Willighagen <[email protected]>
License: AGPL-3
Version: 2.17.1
Built: 2024-11-07 03:26:58 UTC
Source: https://github.com/bioc/BridgeDbR

Help Index


BridgeDbR Package.

Description

R package for using BridgeDb directly from R.

Author(s)

Christ Leemans Anwesha Bohler Denise Slenter Lars Eijssen Tooba Abbassi-Daloii

Maintainer: Egon Willighagen <[email protected]>


Determines if the full name corresponds to any known data source.

Description

Data sources are defined by a title and a short system code. This method determines if a data source is known with the given full name.

Usage

fullNameExists(name)

Arguments

name

full name of the data source

Value

exists

boolean that indicates if a data is known with the given name

Author(s)

Egon Willighagen

Examples

exists <- fullNameExists("HMDB")

Returns the attributes of the given identifier.

Description

Returns the attributes of the given identifier.

Usage

getAttributes(mapper, source, identifier)

Arguments

mapper

loaded BridgeDb identifier mapper

source

system code of the data source

identifier

identifier to return the attributes for

Value

mappings

a vector of attributes

Author(s)

Egon Willighagen

Examples

## Not run: 
location <- getDatabase("Homo sapiens")
mapper <- loadDatabase(location)
getAttributes(mapper, "L", "672")

## End(Not run)

Method to list the BridgeDb identifier mapping file names as available from the download site.

Description

This method returns a list of file names of BridgeDb identifier mapping files as they are available from the mapping file download site. The optional code parameter can be used to restrict the list to a specific organism.

Occassionally, the ID mapping file download website changes the pattern of the file names. In that case, you can provide an alternative filename pattern to recognize files on the download site.

This method uses data from https://bridgedb.github.io/data/gene_database/.

Usage

getBridgeNames(code, website, pattern)

Arguments

code

the organism code

website

optional parameter that allows you to provide a different location to download BridgeDb Derby files from.

pattern

optional parameter to change the filename pattern of the BridgeDb Derby files.

Value

list

the list of available BridgeDb mapping files

Author(s)

Egon Willighagen Christ Leemans

Examples

files <- getBridgeNames("Hs")
## Not run: 
prereleases <- getBridgeNames(
    website="http://bridgedb.org/data/gene_database/pre-release/",
    pattern="metabolites_\d*.bridge"
)

## End(Not run)

Downloads a identifier mapping database for the given organism.

Description

Downloads a identifier mapping database for the given organism. The optional location parameter can be used to indicate where the file should be stored. If not give, it will save it in a temporary folder.

This method extracts links from https://bridgedb.github.io/data/gene_database/ to identifier mapping databases hosted on Zenodo and Figshare, two public data archives.

Usage

getDatabase(organism,location,website)

Arguments

organism

the organism name

location

optional parameter to indicate where the database should be saved

website

optional URL of the server where to look for BridgeDb identifier mapping databases

Value

location

the location where the database was saved

Author(s)

Egon Willighagen Christ Leemans

Examples

## Not run: location <- getDatabase("Bacillus subtilis")
## Not run: location <- getDatabase("Homo sapiens")

Return a DataSource object based on either a name, Bioregistry.io prefix, or system code.

Description

Return a DataSource object based on either a name, Bioregistry.io prefix, or system code.

Usage

getDataSource(name,code,prefix)

Arguments

name

the name of the data source

code

the system code of the data source

prefix

the Bioregistry.io prefix of the data source

Value

dataSource

a DataSource Java object

Author(s)

Egon Willighagen

Examples

dataSource <- getDataSource(code="Ce")

Return the name of a particular data source.

Description

Data sources are defined by a title and a short system code. This method converts a system code into a full name.

Usage

getFullName(syscode)

Arguments

syscode

the system code of the data source

Value

systemCode

the full name of the data source

Author(s)

Egon Willighagen Christ Leemans

Examples

name <- getFullName("Ce")

Return a list of data sources of which the identifier pattern matches the identifier given.

Description

This method runs through all data sources it knows about, and looks for sources of which the identifier pattern matches the given identifier.

Usage

getMatchingSources(identifier)

Arguments

identifier

identifier to test

Value

list

list of matching data sources

Author(s)

Egon Willighagen Christ Leemans

Examples

list <- getMatchingSources("555")

Return the code of a particular organism.

Description

This method converts a organism latin name into a code.

Usage

getOrganismCode(name)

Arguments

name

latin name of an organism

Value

systemCode

the code of the organism

Author(s)

Egon Willighagen Christ Leemans

Examples

systemCode <- getOrganismCode("Mus musculus")

BridgeDb database properties.

Description

Gets the properties of an BridgeDb ID mapping database.

Usage

getProperties(mapper)

Arguments

mapper

loaded BridgeDb identifier mapper

Value

properties

a data frame with the properties

Author(s)

Egon Willighagen

Examples

## Not run: 
location <- getDatabase("Bacillus subtilis")
mapper <- loadDatabase(location)
getProperties(mapper)

## End(Not run)

Return the system code of a particular data source.

Description

Data sources are defined by a title and a short system code. This method converts a name into a system code.

Usage

getSystemCode(name)

Arguments

name

name of the data source

Value

systemCode

the system code of the data source

Author(s)

Egon Willighagen Christ Leemans

Examples

systemCode <- getSystemCode("ChEBI")

Loads a BridgeDb identifier mapping database (.bridge file) as an IDMapper Java-Object.

Description

Loads a BridgeDb identifier mapping database (.bridge file) as an IDMapper Java-Object.

Usage

loadDatabase(location)

Arguments

location

location on the hard disk of the BridgeDb file

Details

The return Java-Object is a Java class implementing the BridgeDb IDMapper interface. It is the required mapper class that is used as input for other methods that need an IDMapper.

Value

mapper

an IDMapper object

Author(s)

Egon Willighagen

Examples

## Not run: 
location <- getDatabase("Bacillus subtilis")
mapper <- loadDatabase(location)

## End(Not run)

Converts one identifier into other identifiers for the given target data source.

Description

Converts one identifier into other identifiers for the given target data source.

Usage

map(mapper, source, identifier, target, compactIdentifier)

Arguments

mapper

loaded BridgeDb identifier mapper

source

system code of the data source

identifier

identifier to be converted

target

system code of the target data source (optional)

compactIdentifier

the Bioregistry.io compact identifier to convert

Value

mappings

a data frame of mapped identifiers for the target data source

Author(s)

Egon Willighagen

Examples

## Not run: 
location <- getDatabase("Bacillus subtilis")
mapper <- loadDatabase(location)
map(mapper, "En", "BSn5_00025", "S")
map(mapper, "En", "BSn5_00025")
location <- getDatabase("Homo sapiens")
mapper <- loadDatabase(location)
map(mapper, "En", "ENSG00000139618")
map(mapper, compactIdentifier="uniprot:P51587")

## End(Not run)

Converts multiple identifiers into other identifiers for the given target data source.

Description

Converts one identifier into other identifiers for the given target data source.

Usage

maps(mapper, identifiers, target)

Arguments

mapper

loaded BridgeDb identifier mapper

identifiers

data frame with identifiers to be converted, with a source and a identifier column

target

system code of the target data source (optional)

Value

mappings

a data frame of mapped identifiers for the target data source

Author(s)

Egon Willighagen

Examples

## Not run: 
location <- getDatabase("Bacillus subtilis")
mapper <- loadDatabase(location)
input = data.frame(
  source= c("L"),
  identifier= c("885041")
)
maps(mapper,input)

## End(Not run)

Registers a new DataSource based on the given name or system code.

Description

Return a DataSource of the newly registered data source, based on either a name or system code.

Usage

registerDataSource(code,name)

Arguments

code

the system code of the data source

name

the name of the data source

Value

dataSource

a DataSource Java object

Author(s)

Egon Willighagen

Examples

newDataSource <- registerDataSource(code="Cks", name="KNApSAcK")

Determines if the system code corresponds to any known data source.

Description

Data sources are defined by a title and a short system code. This method determines if a data source is known with the given system code.

Usage

systemCodeExists(code)

Arguments

code

system code of the data source

Value

exists

boolean that indicates if a data is known with the given system code

Author(s)

Egon Willighagen

Examples

exists <- systemCodeExists("Ce")

Checks if the given identifier exists

Description

Checks if the given identifier exists in the given mapping file

Usage

xrefExists(mapper, source, identifier, compactIdentifier)

Arguments

mapper

loaded BridgeDb identifier mapper

source

system code of the data source

identifier

identifier to be searched

compactIdentifier

the Bioregistry.io compact identifier to check

Value

boolean

true, if the given identifier is found in the mapping database

Author(s)

Egon Willighagen

Examples

## Not run: 
location <- getDatabase("Bacillus subtilis")
mapper <- loadDatabase(location)
xrefExists(mapper, "L", "885041")
xrefExists(mapper, compactIdentifier="ncbigene:885041")

## End(Not run)