Changes in version 1.23.1 (2020-04-18)                 

    o   ASSIGN no longer changes the working directory

    o   ASSIGN requires that output files do not exist before functions run

                       Changes in version 1.17.2                        

    o   Bugfix ComBat.step2 by forcing ComBat input to be a matrix

    o   Added new argument to assign.wrapper to specify direction of signature genes.

    o   parameters file in assign.wrapper is now in yaml format.