Package: ASSIGN Type: Package Title: Adaptive Signature Selection and InteGratioN (ASSIGN) Version: 1.49.0 Date: 2014-10-30 Author: Ying Shen, Andrea H. Bild, W. Evan Johnson, and Mumtehena Rahman Authors@R: c(person(given="Ying", family="Shen", email="yshen3@bu.edu", role=c("aut")), person(given=c("Andrea","H."), family="Bild", email="abild@coh.org", role=c("aut")), person(given=c("W.", "Evan"), family="Johnson", email="wej@bu.edu", role=c("aut"), comment = c(ORCID = "0000-0002-6247-6595")), person(given="Mumtehena", family="Rahman", email="moom.rahman@utah.edu", role=c("aut")), person(given="David", family="Jenkins", email="dfj@bu.edu", role=c("aut","cre"), comment = c(ORCID = "0000-0002-7451-4288"))) Maintainer: Ying Shen , W. Evan Johnson , David Jenkins , Mumtehena Rahman Depends: R (>= 3.4) Description: ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literature or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature. License: MIT + file LICENSE Encoding: UTF-8 LazyData: true Imports: gplots, graphics, grDevices, msm, Rlab, stats, sva, utils, ggplot2, yaml biocViews: Software, GeneExpression, Pathways, Bayesian Suggests: testthat, BiocStyle, lintr, knitr, rmarkdown RoxygenNote: 7.1.0 VignetteBuilder: knitr URL: https://compbiomed.github.io/ASSIGN/ BugReports: https://github.com/compbiomed/ASSIGN/issues Config/pak/sysreqs: libpng-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:38:54 UTC RemoteUrl: https://github.com/bioc/ASSIGN RemoteRef: HEAD RemoteSha: a0d4832531cefb7ff490c788e3601e1d5260b966 NeedsCompilation: no Packaged: 2026-06-20 10:17:20 UTC; root