{"geneset":"HALLMARK_TNFA_SIGNALING_VIA_NFKB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TNFA_SIGNALING_VIA_NFKB","description":"Genes regulated by NF-kB in response to TNF [GeneID=7124]."} {"geneset":"HALLMARK_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA","description":"Genes up-regulated in response to low oxygen levels (hypoxia)."} {"geneset":"HALLMARK_CHOLESTEROL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_CHOLESTEROL_HOMEOSTASIS","description":"Genes involved in cholesterol homeostasis."} {"geneset":"HALLMARK_MITOTIC_SPINDLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MITOTIC_SPINDLE","description":"Genes important for mitotic spindle assembly."} {"geneset":"HALLMARK_WNT_BETA_CATENIN_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_WNT_BETA_CATENIN_SIGNALING","description":"Genes up-regulated by activation of WNT signaling through accumulation of beta catenin CTNNB1 [GeneID=1499]."} {"geneset":"HALLMARK_TGF_BETA_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TGF_BETA_SIGNALING","description":"Genes up-regulated in response to TGFB1 [GeneID=7040]."} {"geneset":"HALLMARK_IL6_JAK_STAT3_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL6_JAK_STAT3_SIGNALING","description":"Genes up-regulated by IL6 [GeneID=3569] via STAT3 [GeneID=6774], e.g., during acute phase response."} {"geneset":"HALLMARK_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_DNA_REPAIR","description":"Genes involved in DNA repair."} {"geneset":"HALLMARK_G2M_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_G2M_CHECKPOINT","description":"Genes involved in the G2/M checkpoint, as in progression through the cell division cycle."} {"geneset":"HALLMARK_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APOPTOSIS","description":"Genes mediating programmed cell death (apoptosis) by activation of caspases."} {"geneset":"HALLMARK_NOTCH_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_NOTCH_SIGNALING","description":"Genes up-regulated by activation of Notch signaling."} {"geneset":"HALLMARK_ADIPOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ADIPOGENESIS","description":"Genes up-regulated during adipocyte differentiation (adipogenesis)."} {"geneset":"HALLMARK_ESTROGEN_RESPONSE_EARLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_EARLY","description":"Genes defining early response to estrogen."} {"geneset":"HALLMARK_ESTROGEN_RESPONSE_LATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_LATE","description":"Genes defining late response to estrogen."} {"geneset":"HALLMARK_ANDROGEN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ANDROGEN_RESPONSE","description":"Genes defining response to androgens."} {"geneset":"HALLMARK_MYOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYOGENESIS","description":"Genes involved in development of skeletal muscle (myogenesis)."} {"geneset":"HALLMARK_PROTEIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PROTEIN_SECRETION","description":"Genes involved in protein secretion pathway."} {"geneset":"HALLMARK_INTERFERON_ALPHA_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_ALPHA_RESPONSE","description":"Genes up-regulated in response to alpha interferon proteins."} {"geneset":"HALLMARK_INTERFERON_GAMMA_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE","description":"Genes up-regulated in response to IFNG [GeneID=3458]."} {"geneset":"HALLMARK_APICAL_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APICAL_JUNCTION","description":"Genes encoding components of apical junction complex."} {"geneset":"HALLMARK_APICAL_SURFACE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APICAL_SURFACE","description":"Genes encoding proteins over-represented on the apical surface of epithelial cells, e.g., important for cell polarity (apical area)."} {"geneset":"HALLMARK_HEDGEHOG_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEDGEHOG_SIGNALING","description":"Genes up-regulated by activation of hedgehog signaling."} {"geneset":"HALLMARK_COMPLEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COMPLEMENT","description":"Genes encoding components of the complement system, which is part of the innate immune system."} {"geneset":"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UNFOLDED_PROTEIN_RESPONSE","description":"Genes up-regulated during unfolded protein response, a cellular stress response related to the endoplasmic reticulum."} {"geneset":"HALLMARK_PI3K_AKT_MTOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PI3K_AKT_MTOR_SIGNALING","description":"Genes up-regulated by activation of the PI3K/AKT/mTOR pathway."} {"geneset":"HALLMARK_MTORC1_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MTORC1_SIGNALING","description":"Genes up-regulated through activation of mTORC1 complex."} {"geneset":"HALLMARK_E2F_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_E2F_TARGETS","description":"Genes encoding cell cycle related targets of E2F transcription factors."} {"geneset":"HALLMARK_MYC_TARGETS_V1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYC_TARGETS_V1","description":"A subgroup of genes regulated by MYC - version 1 (v1)."} {"geneset":"HALLMARK_MYC_TARGETS_V2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYC_TARGETS_V2","description":"A subgroup of genes regulated by MYC - version 2 (v2)."} {"geneset":"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","description":"Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis."} {"geneset":"HALLMARK_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INFLAMMATORY_RESPONSE","description":"Genes defining inflammatory response."} {"geneset":"HALLMARK_XENOBIOTIC_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_XENOBIOTIC_METABOLISM","description":"Genes encoding proteins involved in processing of drugs and other xenobiotics."} {"geneset":"HALLMARK_FATTY_ACID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_FATTY_ACID_METABOLISM","description":"Genes encoding proteins involved in metabolism of fatty acids."} {"geneset":"HALLMARK_OXIDATIVE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_OXIDATIVE_PHOSPHORYLATION","description":"Genes encoding proteins involved in oxidative phosphorylation."} {"geneset":"HALLMARK_GLYCOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_GLYCOLYSIS","description":"Genes encoding proteins involved in glycolysis and gluconeogenesis."} {"geneset":"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","description":"Genes up-regulated by reactive oxigen species (ROS)."} {"geneset":"HALLMARK_P53_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_P53_PATHWAY","description":"Genes involved in p53 pathways and networks."} {"geneset":"HALLMARK_UV_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_UP","description":"Genes up-regulated in response to ultraviolet (UV) radiation."} {"geneset":"HALLMARK_UV_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_DN","description":"Genes down-regulated in response to ultraviolet (UV) radiation."} {"geneset":"HALLMARK_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ANGIOGENESIS","description":"Genes up-regulated during formation of blood vessels (angiogenesis)."} {"geneset":"HALLMARK_HEME_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEME_METABOLISM","description":"Genes involved in metabolism of heme (a cofactor consisting of iron and porphyrin) and erythroblast differentiation."} {"geneset":"HALLMARK_COAGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COAGULATION","description":"Genes encoding components of blood coagulation system; also up-regulated in platelets."} {"geneset":"HALLMARK_IL2_STAT5_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL2_STAT5_SIGNALING","description":"Genes up-regulated by STAT5 in response to IL2 stimulation."} {"geneset":"HALLMARK_BILE_ACID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_BILE_ACID_METABOLISM","description":"Genes involve in metabolism of bile acids and salts."} {"geneset":"HALLMARK_PEROXISOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PEROXISOME","description":"Genes encoding components of peroxisome."} {"geneset":"HALLMARK_ALLOGRAFT_REJECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ALLOGRAFT_REJECTION","description":"Genes up-regulated during transplant rejection."} {"geneset":"HALLMARK_SPERMATOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_SPERMATOGENESIS","description":"Genes up-regulated during production of male gametes (sperm), as in spermatogenesis."} {"geneset":"HALLMARK_KRAS_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_UP","description":"Genes up-regulated by KRAS activation."} {"geneset":"HALLMARK_KRAS_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_DN","description":"Genes down-regulated by KRAS activation."} {"geneset":"HALLMARK_PANCREAS_BETA_CELLS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PANCREAS_BETA_CELLS","description":"Genes specifically up-regulated in pancreatic beta cells."} {"geneset":"chr5q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q23","description":"Genes in cytogenetic band chr5q23"} {"geneset":"chr16q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16q24","description":"Genes in cytogenetic band chr16q24"} {"geneset":"chr8q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8q24","description":"Genes in cytogenetic band chr8q24"} {"geneset":"chr13q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q11","description":"Genes in cytogenetic band chr13q11"} {"geneset":"chr7p21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7p21","description":"Genes in cytogenetic band chr7p21"} {"geneset":"chr10q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10q23","description":"Genes in cytogenetic band chr10q23"} {"geneset":"chr13q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q13","description":"Genes in cytogenetic band chr13q13"} {"geneset":"chr10q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10q21","description":"Genes in cytogenetic band chr10q21"} {"geneset":"chr1p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p13","description":"Genes in cytogenetic band chr1p13"} {"geneset":"chrxp21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxp21","description":"Genes in cytogenetic band chrxp21"} {"geneset":"chr4q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q12","description":"Genes in cytogenetic band chr4q12"} {"geneset":"chr6q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q13","description":"Genes in cytogenetic band chr6q13"} {"geneset":"chr2p22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p22","description":"Genes in cytogenetic band chr2p22"} {"geneset":"chr18q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr18q23","description":"Genes in cytogenetic band chr18q23"} {"geneset":"chr8p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8p11","description":"Genes in cytogenetic band chr8p11"} {"geneset":"chr1p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p11","description":"Genes in cytogenetic band chr1p11"} {"geneset":"chr9p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9p12","description":"Genes in cytogenetic band chr9p12"} {"geneset":"chr20p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr20p12","description":"Genes in cytogenetic band chr20p12"} {"geneset":"chr7p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7p13","description":"Genes in cytogenetic band chr7p13"} {"geneset":"chr4p16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4p16","description":"Genes in cytogenetic band chr4p16"} {"geneset":"chr8q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8q22","description":"Genes in cytogenetic band chr8q22"} {"geneset":"chr14q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q11","description":"Genes in cytogenetic band chr14q11"} {"geneset":"chryp11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chryp11","description":"Genes in cytogenetic band chryp11"} {"geneset":"chr10q25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10q25","description":"Genes in cytogenetic band chr10q25"} {"geneset":"chr11q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q","description":"Genes in cytogenetic band chr11q"} {"geneset":"chr4p14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4p14","description":"Genes in cytogenetic band chr4p14"} {"geneset":"chr15q26","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q26","description":"Genes in cytogenetic band chr15q26"} {"geneset":"chr12q15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q15","description":"Genes in cytogenetic band chr12q15"} {"geneset":"chr4p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4p12","description":"Genes in cytogenetic band chr4p12"} {"geneset":"chr9q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9q12","description":"Genes in cytogenetic band chr9q12"} {"geneset":"chr2q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q22","description":"Genes in cytogenetic band chr2q22"} {"geneset":"chr9q33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9q33","description":"Genes in cytogenetic band chr9q33"} {"geneset":"chr18p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr18p","description":"Genes in cytogenetic band chr18p"} {"geneset":"chr3q28","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q28","description":"Genes in cytogenetic band chr3q28"} {"geneset":"chr12q14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q14","description":"Genes in cytogenetic band chr12q14"} {"geneset":"chr2q36","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q36","description":"Genes in cytogenetic band chr2q36"} {"geneset":"chr9q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9q22","description":"Genes in cytogenetic band chr9q22"} {"geneset":"chr3p22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p22","description":"Genes in cytogenetic band chr3p22"} {"geneset":"chrxq","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq","description":"Genes in cytogenetic band chrxq"} {"geneset":"chr6p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6p11","description":"Genes in cytogenetic band chr6p11"} {"geneset":"chr12q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q24","description":"Genes in cytogenetic band chr12q24"} {"geneset":"chr2q32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q32","description":"Genes in cytogenetic band chr2q32"} {"geneset":"chr4q35","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q35","description":"Genes in cytogenetic band chr4q35"} {"geneset":"chr3p14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p14","description":"Genes in cytogenetic band chr3p14"} {"geneset":"chr22q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr22q","description":"Genes in cytogenetic band chr22q"} {"geneset":"chr15q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q24","description":"Genes in cytogenetic band chr15q24"} {"geneset":"chr2p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p","description":"Genes in cytogenetic band chr2p"} {"geneset":"chr13q31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q31","description":"Genes in cytogenetic band chr13q31"} {"geneset":"chr19p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr19p13","description":"Genes in cytogenetic band chr19p13"} {"geneset":"chr12q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q22","description":"Genes in cytogenetic band chr12q22"} {"geneset":"chr7p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7p","description":"Genes in cytogenetic band chr7p"} {"geneset":"chr11q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q22","description":"Genes in cytogenetic band chr11q22"} {"geneset":"chrxq28","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq28","description":"Genes in cytogenetic band chrxq28"} {"geneset":"chr16q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16q22","description":"Genes in cytogenetic band chr16q22"} {"geneset":"chr11q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q24","description":"Genes in cytogenetic band chr11q24"} {"geneset":"chr5q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q12","description":"Genes in cytogenetic band chr5q12"} {"geneset":"chr10p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10p11","description":"Genes in cytogenetic band chr10p11"} {"geneset":"chr5q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q21","description":"Genes in cytogenetic band chr5q21"} {"geneset":"chr14q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q21","description":"Genes in cytogenetic band chr14q21"} {"geneset":"chrxq12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq12","description":"Genes in cytogenetic band chrxq12"} {"geneset":"chr1p35","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p35","description":"Genes in cytogenetic band chr1p35"} {"geneset":"chr3p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p12","description":"Genes in cytogenetic band chr3p12"} {"geneset":"chr4q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q21","description":"Genes in cytogenetic band chr4q21"} {"geneset":"chr10p15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10p15","description":"Genes in cytogenetic band chr10p15"} {"geneset":"chr18q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr18q21","description":"Genes in cytogenetic band chr18q21"} {"geneset":"chr1p33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p33","description":"Genes in cytogenetic band chr1p33"} {"geneset":"chr11q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q12","description":"Genes in cytogenetic band chr11q12"} {"geneset":"chr17q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17q22","description":"Genes in cytogenetic band chr17q22"} {"geneset":"chr1p31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p31","description":"Genes in cytogenetic band chr1p31"} {"geneset":"chr10p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10p13","description":"Genes in cytogenetic band chr10p13"} {"geneset":"chr14q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q13","description":"Genes in cytogenetic band chr14q13"} {"geneset":"chr2q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q24","description":"Genes in cytogenetic band chr2q24"} {"geneset":"chr22q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr22q13","description":"Genes in cytogenetic band chr22q13"} {"geneset":"chr15q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q11","description":"Genes in cytogenetic band chr15q11"} {"geneset":"chr1q43","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q43","description":"Genes in cytogenetic band chr1q43"} {"geneset":"chr19p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr19p","description":"Genes in cytogenetic band chr19p"} {"geneset":"chr3q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q24","description":"Genes in cytogenetic band chr3q24"} {"geneset":"chr22q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr22q11","description":"Genes in cytogenetic band chr22q11"} {"geneset":"chr7p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7p11","description":"Genes in cytogenetic band chr7p11"} {"geneset":"chr16q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16q13","description":"Genes in cytogenetic band chr16q13"} {"geneset":"chr1p22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p22","description":"Genes in cytogenetic band chr1p22"} {"geneset":"chr12p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12p","description":"Genes in cytogenetic band chr12p"} {"geneset":"chr2q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q11","description":"Genes in cytogenetic band chr2q11"} {"geneset":"chr9p21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9p21","description":"Genes in cytogenetic band chr9p21"} {"geneset":"chr4q33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q33","description":"Genes in cytogenetic band chr4q33"} {"geneset":"chr2p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p11","description":"Genes in cytogenetic band chr2p11"} {"geneset":"chr2q34","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q34","description":"Genes in cytogenetic band chr2q34"} {"geneset":"chr17q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17q23","description":"Genes in cytogenetic band chr17q23"} {"geneset":"chr14q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q23","description":"Genes in cytogenetic band chr14q23"} {"geneset":"chr5q33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q33","description":"Genes in cytogenetic band chr5q33"} {"geneset":"chr6q27","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q27","description":"Genes in cytogenetic band chr6q27"} {"geneset":"chr3q26","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q26","description":"Genes in cytogenetic band chr3q26"} {"geneset":"chr10q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10q11","description":"Genes in cytogenetic band chr10q11"} {"geneset":"chr5p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5p12","description":"Genes in cytogenetic band chr5p12"} {"geneset":"chr1q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q21","description":"Genes in cytogenetic band chr1q21"} {"geneset":"chr4q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q24","description":"Genes in cytogenetic band chr4q24"} {"geneset":"chr7q31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q31","description":"Genes in cytogenetic band chr7q31"} {"geneset":"chr6p21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6p21","description":"Genes in cytogenetic band chr6p21"} {"geneset":"chr17q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17q","description":"Genes in cytogenetic band chr17q"} {"geneset":"chr5q15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q15","description":"Genes in cytogenetic band chr5q15"} {"geneset":"chr2q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q13","description":"Genes in cytogenetic band chr2q13"} {"geneset":"chr1q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q23","description":"Genes in cytogenetic band chr1q23"} {"geneset":"chr6q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q23","description":"Genes in cytogenetic band chr6q23"} {"geneset":"chr11q14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q14","description":"Genes in cytogenetic band chr11q14"} {"geneset":"chr5p14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5p14","description":"Genes in cytogenetic band chr5p14"} {"geneset":"chr5q31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q31","description":"Genes in cytogenetic band chr5q31"} {"geneset":"chr2p24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p24","description":"Genes in cytogenetic band chr2p24"} {"geneset":"chr9p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9p11","description":"Genes in cytogenetic band chr9p11"} {"geneset":"chr4q26","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q26","description":"Genes in cytogenetic band chr4q26"} {"geneset":"chr1q25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q25","description":"Genes in cytogenetic band chr1q25"} {"geneset":"chrxq11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq11","description":"Genes in cytogenetic band chrxq11"} {"geneset":"chr5q14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q14","description":"Genes in cytogenetic band chr5q14"} {"geneset":"chr4q28","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q28","description":"Genes in cytogenetic band chr4q28"} {"geneset":"chr1q42","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q42","description":"Genes in cytogenetic band chr1q42"} {"geneset":"chr6p25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6p25","description":"Genes in cytogenetic band chr6p25"} {"geneset":"chr13q34","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q34","description":"Genes in cytogenetic band chr13q34"} {"geneset":"chr8q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8q12","description":"Genes in cytogenetic band chr8q12"} {"geneset":"chr4q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q22","description":"Genes in cytogenetic band chr4q22"} {"geneset":"chr7q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q22","description":"Genes in cytogenetic band chr7q22"} {"geneset":"chr6p23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6p23","description":"Genes in cytogenetic band chr6p23"} {"geneset":"chr8p21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8p21","description":"Genes in cytogenetic band chr8p21"} {"geneset":"chr5q35","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q35","description":"Genes in cytogenetic band chr5q35"} {"geneset":"chr13q32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q32","description":"Genes in cytogenetic band chr13q32"} {"geneset":"chr12q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q12","description":"Genes in cytogenetic band chr12q12"} {"geneset":"chr3p24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p24","description":"Genes in cytogenetic band chr3p24"} {"geneset":"chr7q33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q33","description":"Genes in cytogenetic band chr7q33"} {"geneset":"chr12p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12p12","description":"Genes in cytogenetic band chr12p12"} {"geneset":"chr9p23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9p23","description":"Genes in cytogenetic band chr9p23"} {"geneset":"chr7p14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7p14","description":"Genes in cytogenetic band chr7p14"} {"geneset":"chr6q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q21","description":"Genes in cytogenetic band chr6q21"} {"geneset":"chryq11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chryq11","description":"Genes in cytogenetic band chryq11"} {"geneset":"chr15q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q13","description":"Genes in cytogenetic band chr15q13"} {"geneset":"chr3q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q22","description":"Genes in cytogenetic band chr3q22"} {"geneset":"chr6q15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q15","description":"Genes in cytogenetic band chr6q15"} {"geneset":"chr4q31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q31","description":"Genes in cytogenetic band chr4q31"} {"geneset":"chr3q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q12","description":"Genes in cytogenetic band chr3q12"} {"geneset":"chr13q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q22","description":"Genes in cytogenetic band chr13q22"} {"geneset":"chr15q15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q15","description":"Genes in cytogenetic band chr15q15"} {"geneset":"chr3p26","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p26","description":"Genes in cytogenetic band chr3p26"} {"geneset":"chr17q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17q12","description":"Genes in cytogenetic band chr17q12"} {"geneset":"chr11p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11p12","description":"Genes in cytogenetic band chr11p12"} {"geneset":"chr7p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7p12","description":"Genes in cytogenetic band chr7p12"} {"geneset":"chr6q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q","description":"Genes in cytogenetic band chr6q"} {"geneset":"chrxq21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq21","description":"Genes in cytogenetic band chrxq21"} {"geneset":"chr19q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr19q13","description":"Genes in cytogenetic band chr19q13"} {"geneset":"chr16p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16p12","description":"Genes in cytogenetic band chr16p12"} {"geneset":"chr1q32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q32","description":"Genes in cytogenetic band chr1q32"} {"geneset":"chr8p23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8p23","description":"Genes in cytogenetic band chr8p23"} {"geneset":"chrxq23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq23","description":"Genes in cytogenetic band chrxq23"} {"geneset":"chr2p15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p15","description":"Genes in cytogenetic band chr2p15"} {"geneset":"chr18q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr18q12","description":"Genes in cytogenetic band chr18q12"} {"geneset":"chr17p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17p13","description":"Genes in cytogenetic band chr17p13"} {"geneset":"chr14q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q","description":"Genes in cytogenetic band chr14q"} {"geneset":"chr11p14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11p14","description":"Genes in cytogenetic band chr11p14"} {"geneset":"chr1q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q","description":"Genes in cytogenetic band chr1q"} {"geneset":"chr9q32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9q32","description":"Genes in cytogenetic band chr9q32"} {"geneset":"chr20q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr20q12","description":"Genes in cytogenetic band chr20q12"} {"geneset":"chr14q32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q32","description":"Genes in cytogenetic band chr14q32"} {"geneset":"chr7p22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7p22","description":"Genes in cytogenetic band chr7p22"} {"geneset":"chr5q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q","description":"Genes in cytogenetic band chr5q"} {"geneset":"chr21q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr21q21","description":"Genes in cytogenetic band chr21q21"} {"geneset":"chr2p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p13","description":"Genes in cytogenetic band chr2p13"} {"geneset":"chr16q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16q12","description":"Genes in cytogenetic band chr16q12"} {"geneset":"chr3p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p","description":"Genes in cytogenetic band chr3p"} {"geneset":"chr10q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10q22","description":"Genes in cytogenetic band chr10q22"} {"geneset":"chr17p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17p11","description":"Genes in cytogenetic band chr17p11"} {"geneset":"chr15q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q22","description":"Genes in cytogenetic band chr15q22"} {"geneset":"chr10q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10q","description":"Genes in cytogenetic band chr10q"} {"geneset":"chr1q31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q31","description":"Genes in cytogenetic band chr1q31"} {"geneset":"chr10q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10q24","description":"Genes in cytogenetic band chr10q24"} {"geneset":"chr13q14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q14","description":"Genes in cytogenetic band chr13q14"} {"geneset":"chr11p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11p","description":"Genes in cytogenetic band chr11p"} {"geneset":"chr14q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q12","description":"Genes in cytogenetic band chr14q12"} {"geneset":"chr4q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q","description":"Genes in cytogenetic band chr4q"} {"geneset":"chr1p34","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p34","description":"Genes in cytogenetic band chr1p34"} {"geneset":"chr2q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q23","description":"Genes in cytogenetic band chr2q23"} {"geneset":"chr6q16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q16","description":"Genes in cytogenetic band chr6q16"} {"geneset":"chr16q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16q21","description":"Genes in cytogenetic band chr16q21"} {"geneset":"chr9q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9q13","description":"Genes in cytogenetic band chr9q13"} {"geneset":"chr15q25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q25","description":"Genes in cytogenetic band chr15q25"} {"geneset":"chr18q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr18q22","description":"Genes in cytogenetic band chr18q22"} {"geneset":"chr2q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q21","description":"Genes in cytogenetic band chr2q21"} {"geneset":"chr3p25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p25","description":"Genes in cytogenetic band chr3p25"} {"geneset":"chr20p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr20p13","description":"Genes in cytogenetic band chr20p13"} {"geneset":"chr8q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8q21","description":"Genes in cytogenetic band chr8q21"} {"geneset":"chr4p15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4p15","description":"Genes in cytogenetic band chr4p15"} {"geneset":"chr12p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12p11","description":"Genes in cytogenetic band chr12p11"} {"geneset":"chr9p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9p13","description":"Genes in cytogenetic band chr9p13"} {"geneset":"chr2q37","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q37","description":"Genes in cytogenetic band chr2q37"} {"geneset":"chr3q29","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q29","description":"Genes in cytogenetic band chr3q29"} {"geneset":"chr16p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16p","description":"Genes in cytogenetic band chr16p"} {"geneset":"chr13q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q12","description":"Genes in cytogenetic band chr13q12"} {"geneset":"chr3p21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p21","description":"Genes in cytogenetic band chr3p21"} {"geneset":"chr1p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p12","description":"Genes in cytogenetic band chr1p12"} {"geneset":"chr4p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4p11","description":"Genes in cytogenetic band chr4p11"} {"geneset":"chr10q26","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10q26","description":"Genes in cytogenetic band chr10q26"} {"geneset":"chr13q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q21","description":"Genes in cytogenetic band chr13q21"} {"geneset":"chr15q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q23","description":"Genes in cytogenetic band chr15q23"} {"geneset":"chr2p21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p21","description":"Genes in cytogenetic band chr2p21"} {"geneset":"chr19q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr19q12","description":"Genes in cytogenetic band chr19q12"} {"geneset":"chr20p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr20p11","description":"Genes in cytogenetic band chr20p11"} {"geneset":"chr5q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q22","description":"Genes in cytogenetic band chr5q22"} {"geneset":"chr4p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4p13","description":"Genes in cytogenetic band chr4p13"} {"geneset":"chr8q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8q23","description":"Genes in cytogenetic band chr8q23"} {"geneset":"chr19p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr19p12","description":"Genes in cytogenetic band chr19p12"} {"geneset":"chr21q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr21q22","description":"Genes in cytogenetic band chr21q22"} {"geneset":"chrxq25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq25","description":"Genes in cytogenetic band chrxq25"} {"geneset":"chr4q34","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q34","description":"Genes in cytogenetic band chr4q34"} {"geneset":"chr11q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q23","description":"Genes in cytogenetic band chr11q23"} {"geneset":"chr10p14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10p14","description":"Genes in cytogenetic band chr10p14"} {"geneset":"chr9q34","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9q34","description":"Genes in cytogenetic band chr9q34"} {"geneset":"chr15q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q","description":"Genes in cytogenetic band chr15q"} {"geneset":"chr7q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q","description":"Genes in cytogenetic band chr7q"} {"geneset":"chr2q33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q33","description":"Genes in cytogenetic band chr2q33"} {"geneset":"chr8q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8q","description":"Genes in cytogenetic band chr8q"} {"geneset":"chr22q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr22q12","description":"Genes in cytogenetic band chr22q12"} {"geneset":"chr6p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6p12","description":"Genes in cytogenetic band chr6p12"} {"geneset":"chr7q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q21","description":"Genes in cytogenetic band chr7q21"} {"geneset":"chr16q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16q23","description":"Genes in cytogenetic band chr16q23"} {"geneset":"chr11q25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q25","description":"Genes in cytogenetic band chr11q25"} {"geneset":"chr5q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q11","description":"Genes in cytogenetic band chr5q11"} {"geneset":"chr21q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr21q11","description":"Genes in cytogenetic band chr21q11"} {"geneset":"chr11q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q13","description":"Genes in cytogenetic band chr11q13"} {"geneset":"chr9p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9p","description":"Genes in cytogenetic band chr9p"} {"geneset":"chr17q25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17q25","description":"Genes in cytogenetic band chr17q25"} {"geneset":"chr6q25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q25","description":"Genes in cytogenetic band chr6q25"} {"geneset":"chr10p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr10p12","description":"Genes in cytogenetic band chr10p12"} {"geneset":"chr7q36","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q36","description":"Genes in cytogenetic band chr7q36"} {"geneset":"chrxp11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxp11","description":"Genes in cytogenetic band chrxp11"} {"geneset":"chr9q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9q21","description":"Genes in cytogenetic band chr9q21"} {"geneset":"chrxp22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxp22","description":"Genes in cytogenetic band chrxp22"} {"geneset":"chr1p32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p32","description":"Genes in cytogenetic band chr1p32"} {"geneset":"chr12q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q21","description":"Genes in cytogenetic band chr12q21"} {"geneset":"chr8p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8p12","description":"Genes in cytogenetic band chr8p12"} {"geneset":"chr11q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q11","description":"Genes in cytogenetic band chr11q11"} {"geneset":"chr12q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q23","description":"Genes in cytogenetic band chr12q23"} {"geneset":"chrxq13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq13","description":"Genes in cytogenetic band chrxq13"} {"geneset":"chr1p36","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p36","description":"Genes in cytogenetic band chr1p36"} {"geneset":"chr2p23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p23","description":"Genes in cytogenetic band chr2p23"} {"geneset":"chr2q31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q31","description":"Genes in cytogenetic band chr2q31"} {"geneset":"chr3p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p13","description":"Genes in cytogenetic band chr3p13"} {"geneset":"chr2q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q","description":"Genes in cytogenetic band chr2q"} {"geneset":"chrxq27","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq27","description":"Genes in cytogenetic band chrxq27"} {"geneset":"chr3p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p11","description":"Genes in cytogenetic band chr3p11"} {"geneset":"chr17q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17q21","description":"Genes in cytogenetic band chr17q21"} {"geneset":"chr13q33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr13q33","description":"Genes in cytogenetic band chr13q33"} {"geneset":"chr11p15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11p15","description":"Genes in cytogenetic band chr11p15"} {"geneset":"chr1p21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p21","description":"Genes in cytogenetic band chr1p21"} {"geneset":"chr3q25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q25","description":"Genes in cytogenetic band chr3q25"} {"geneset":"chr3q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q13","description":"Genes in cytogenetic band chr3q13"} {"geneset":"chr5p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5p13","description":"Genes in cytogenetic band chr5p13"} {"geneset":"chr14q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q22","description":"Genes in cytogenetic band chr14q22"} {"geneset":"chr9p22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9p22","description":"Genes in cytogenetic band chr9p22"} {"geneset":"chr4q27","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q27","description":"Genes in cytogenetic band chr4q27"} {"geneset":"chr2p25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p25","description":"Genes in cytogenetic band chr2p25"} {"geneset":"chr6p24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6p24","description":"Genes in cytogenetic band chr6p24"} {"geneset":"chr1p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1p","description":"Genes in cytogenetic band chr1p"} {"geneset":"chr2q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q12","description":"Genes in cytogenetic band chr2q12"} {"geneset":"chr8q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8q13","description":"Genes in cytogenetic band chr8q13"} {"geneset":"chr2p16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p16","description":"Genes in cytogenetic band chr2p16"} {"geneset":"chr12q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q","description":"Genes in cytogenetic band chr12q"} {"geneset":"chr4q25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q25","description":"Genes in cytogenetic band chr4q25"} {"geneset":"chr20q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr20q13","description":"Genes in cytogenetic band chr20q13"} {"geneset":"chr5q34","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q34","description":"Genes in cytogenetic band chr5q34"} {"geneset":"chr17q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17q24","description":"Genes in cytogenetic band chr17q24"} {"geneset":"chr2q14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q14","description":"Genes in cytogenetic band chr2q14"} {"geneset":"chr7q35","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q35","description":"Genes in cytogenetic band chr7q35"} {"geneset":"chr5q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q13","description":"Genes in cytogenetic band chr5q13"} {"geneset":"chr19q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr19q","description":"Genes in cytogenetic band chr19q"} {"geneset":"chr5q32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5q32","description":"Genes in cytogenetic band chr5q32"} {"geneset":"chr20q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr20q11","description":"Genes in cytogenetic band chr20q11"} {"geneset":"chr6q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q24","description":"Genes in cytogenetic band chr6q24"} {"geneset":"chr5p15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr5p15","description":"Genes in cytogenetic band chr5p15"} {"geneset":"chr1q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q22","description":"Genes in cytogenetic band chr1q22"} {"geneset":"chr6q26","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q26","description":"Genes in cytogenetic band chr6q26"} {"geneset":"chr6p22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6p22","description":"Genes in cytogenetic band chr6p22"} {"geneset":"chr11q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11q21","description":"Genes in cytogenetic band chr11q21"} {"geneset":"chr1q41","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q41","description":"Genes in cytogenetic band chr1q41"} {"geneset":"chr15q14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q14","description":"Genes in cytogenetic band chr15q14"} {"geneset":"chr8q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8q11","description":"Genes in cytogenetic band chr8q11"} {"geneset":"chr1q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q24","description":"Genes in cytogenetic band chr1q24"} {"geneset":"chr4q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q23","description":"Genes in cytogenetic band chr4q23"} {"geneset":"chrxq26","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq26","description":"Genes in cytogenetic band chrxq26"} {"geneset":"chr3q23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q23","description":"Genes in cytogenetic band chr3q23"} {"geneset":"chr3p23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3p23","description":"Genes in cytogenetic band chr3p23"} {"geneset":"chr12q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q13","description":"Genes in cytogenetic band chr12q13"} {"geneset":"chr9q31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9q31","description":"Genes in cytogenetic band chr9q31"} {"geneset":"chr2p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p12","description":"Genes in cytogenetic band chr2p12"} {"geneset":"chr1q44","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q44","description":"Genes in cytogenetic band chr1q44"} {"geneset":"chr7q34","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q34","description":"Genes in cytogenetic band chr7q34"} {"geneset":"chr2q35","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2q35","description":"Genes in cytogenetic band chr2q35"} {"geneset":"chr6q14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q14","description":"Genes in cytogenetic band chr6q14"} {"geneset":"chr16p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16p13","description":"Genes in cytogenetic band chr16p13"} {"geneset":"chr18q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr18q11","description":"Genes in cytogenetic band chr18q11"} {"geneset":"chr3q27","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q27","description":"Genes in cytogenetic band chr3q27"} {"geneset":"chr7q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q11","description":"Genes in cytogenetic band chr7q11"} {"geneset":"chr3q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q21","description":"Genes in cytogenetic band chr3q21"} {"geneset":"chr16p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16p11","description":"Genes in cytogenetic band chr16p11"} {"geneset":"chr12p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12p13","description":"Genes in cytogenetic band chr12p13"} {"geneset":"chr7p15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7p15","description":"Genes in cytogenetic band chr7p15"} {"geneset":"chr3q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q11","description":"Genes in cytogenetic band chr3q11"} {"geneset":"chr6q22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q22","description":"Genes in cytogenetic band chr6q22"} {"geneset":"chr7q32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr7q32","description":"Genes in cytogenetic band chr7q32"} {"geneset":"chr12q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr12q11","description":"Genes in cytogenetic band chr12q11"} {"geneset":"chr18p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr18p11","description":"Genes in cytogenetic band chr18p11"} {"geneset":"chr17q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17q11","description":"Genes in cytogenetic band chr17q11"} {"geneset":"chrxq24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq24","description":"Genes in cytogenetic band chrxq24"} {"geneset":"chr6q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6q12","description":"Genes in cytogenetic band chr6q12"} {"geneset":"chr3q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr3q","description":"Genes in cytogenetic band chr3q"} {"geneset":"chr6p","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr6p","description":"Genes in cytogenetic band chr6p"} {"geneset":"chr21p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr21p11","description":"Genes in cytogenetic band chr21p11"} {"geneset":"chrxq22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chrxq22","description":"Genes in cytogenetic band chrxq22"} {"geneset":"chr9p24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr9p24","description":"Genes in cytogenetic band chr9p24"} {"geneset":"chr11p11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11p11","description":"Genes in cytogenetic band chr11p11"} {"geneset":"chr4q13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q13","description":"Genes in cytogenetic band chr4q13"} {"geneset":"chr16q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr16q11","description":"Genes in cytogenetic band chr16q11"} {"geneset":"chr8p22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr8p22","description":"Genes in cytogenetic band chr8p22"} {"geneset":"chr14q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q24","description":"Genes in cytogenetic band chr14q24"} {"geneset":"chr1q12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr1q12","description":"Genes in cytogenetic band chr1q12"} {"geneset":"chr15q21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr15q21","description":"Genes in cytogenetic band chr15q21"} {"geneset":"chr11p13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr11p13","description":"Genes in cytogenetic band chr11p13"} {"geneset":"chr17p12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr17p12","description":"Genes in cytogenetic band chr17p12"} {"geneset":"chr4q32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q32","description":"Genes in cytogenetic band chr4q32"} {"geneset":"chr4q11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr4q11","description":"Genes in cytogenetic band chr4q11"} {"geneset":"chr14q31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr14q31","description":"Genes in cytogenetic band chr14q31"} {"geneset":"chr2p14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/chr2p14","description":"Genes in cytogenetic band chr2p14"} {"geneset":"KEGG_GLYCOLYSIS_GLUCONEOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOLYSIS_GLUCONEOGENESIS","description":"Glycolysis / Gluconeogenesis"} {"geneset":"KEGG_CITRATE_CYCLE_TCA_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CITRATE_CYCLE_TCA_CYCLE","description":"Citrate cycle (TCA cycle)"} {"geneset":"KEGG_PENTOSE_PHOSPHATE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PENTOSE_PHOSPHATE_PATHWAY","description":"Pentose phosphate pathway"} {"geneset":"KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS","description":"Pentose and glucuronate interconversions"} {"geneset":"KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM","description":"Fructose and mannose metabolism"} {"geneset":"KEGG_GALACTOSE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GALACTOSE_METABOLISM","description":"Galactose metabolism"} {"geneset":"KEGG_ASCORBATE_AND_ALDARATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ASCORBATE_AND_ALDARATE_METABOLISM","description":"Ascorbate and aldarate metabolism"} {"geneset":"KEGG_FATTY_ACID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_FATTY_ACID_METABOLISM","description":"Fatty acid metabolism"} {"geneset":"KEGG_STEROID_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_STEROID_BIOSYNTHESIS","description":"Steroid biosynthesis"} {"geneset":"KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS","description":"Primary bile acid biosynthesis"} {"geneset":"KEGG_STEROID_HORMONE_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_STEROID_HORMONE_BIOSYNTHESIS","description":"Steroid hormone biosynthesis"} {"geneset":"KEGG_OXIDATIVE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_OXIDATIVE_PHOSPHORYLATION","description":"Oxidative phosphorylation"} {"geneset":"KEGG_PURINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PURINE_METABOLISM","description":"Purine metabolism"} {"geneset":"KEGG_PYRIMIDINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PYRIMIDINE_METABOLISM","description":"Pyrimidine metabolism"} {"geneset":"KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM","description":"Alanine, aspartate and glutamate metabolism"} {"geneset":"KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM","description":"Glycine, serine and threonine metabolism"} {"geneset":"KEGG_CYSTEINE_AND_METHIONINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CYSTEINE_AND_METHIONINE_METABOLISM","description":"Cysteine and methionine metabolism"} {"geneset":"KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION","description":"Valine, leucine and isoleucine degradation"} {"geneset":"KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS","description":"Valine, leucine and isoleucine biosynthesis"} {"geneset":"KEGG_LYSINE_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_LYSINE_DEGRADATION","description":"Lysine degradation"} {"geneset":"KEGG_ARGININE_AND_PROLINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ARGININE_AND_PROLINE_METABOLISM","description":"Arginine and proline metabolism"} {"geneset":"KEGG_HISTIDINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_HISTIDINE_METABOLISM","description":"Histidine metabolism"} {"geneset":"KEGG_TYROSINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TYROSINE_METABOLISM","description":"Tyrosine metabolism"} {"geneset":"KEGG_PHENYLALANINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PHENYLALANINE_METABOLISM","description":"Phenylalanine metabolism"} {"geneset":"KEGG_TRYPTOPHAN_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TRYPTOPHAN_METABOLISM","description":"Tryptophan metabolism"} {"geneset":"KEGG_BETA_ALANINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_BETA_ALANINE_METABOLISM","description":"beta-Alanine metabolism"} {"geneset":"KEGG_TAURINE_AND_HYPOTAURINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TAURINE_AND_HYPOTAURINE_METABOLISM","description":"Taurine and hypotaurine metabolism"} {"geneset":"KEGG_SELENOAMINO_ACID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_SELENOAMINO_ACID_METABOLISM","description":"Selenoamino acid metabolism"} {"geneset":"KEGG_GLUTATHIONE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLUTATHIONE_METABOLISM","description":"Glutathione metabolism"} {"geneset":"KEGG_STARCH_AND_SUCROSE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_STARCH_AND_SUCROSE_METABOLISM","description":"Starch and sucrose metabolism"} {"geneset":"KEGG_N_GLYCAN_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_N_GLYCAN_BIOSYNTHESIS","description":"N-Glycan biosynthesis"} {"geneset":"KEGG_OTHER_GLYCAN_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_OTHER_GLYCAN_DEGRADATION","description":"Other glycan degradation"} {"geneset":"KEGG_O_GLYCAN_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_O_GLYCAN_BIOSYNTHESIS","description":"O-Glycan biosynthesis"} {"geneset":"KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM","description":"Amino sugar and nucleotide sugar metabolism"} {"geneset":"KEGG_GLYCOSAMINOGLYCAN_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSAMINOGLYCAN_DEGRADATION","description":"Glycosaminoglycan degradation"} {"geneset":"KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE","description":"Glycosaminoglycan biosynthesis - chondroitin sulfate"} {"geneset":"KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE","description":"Glycosaminoglycan biosynthesis - keratan sulfate"} {"geneset":"KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE","description":"Glycosaminoglycan biosynthesis - heparan sulfate"} {"geneset":"KEGG_GLYCEROLIPID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCEROLIPID_METABOLISM","description":"Glycerolipid metabolism"} {"geneset":"KEGG_INOSITOL_PHOSPHATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_INOSITOL_PHOSPHATE_METABOLISM","description":"Inositol phosphate metabolism"} {"geneset":"KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS","description":"Glycosylphosphatidylinositol(GPI)-anchor biosynthesis"} {"geneset":"KEGG_GLYCEROPHOSPHOLIPID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCEROPHOSPHOLIPID_METABOLISM","description":"Glycerophospholipid metabolism"} {"geneset":"KEGG_ETHER_LIPID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ETHER_LIPID_METABOLISM","description":"Ether lipid metabolism"} {"geneset":"KEGG_ARACHIDONIC_ACID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ARACHIDONIC_ACID_METABOLISM","description":"Arachidonic acid metabolism"} {"geneset":"KEGG_LINOLEIC_ACID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_LINOLEIC_ACID_METABOLISM","description":"Linoleic acid metabolism"} {"geneset":"KEGG_ALPHA_LINOLENIC_ACID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ALPHA_LINOLENIC_ACID_METABOLISM","description":"alpha-Linolenic acid metabolism"} {"geneset":"KEGG_SPHINGOLIPID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_SPHINGOLIPID_METABOLISM","description":"Sphingolipid metabolism"} {"geneset":"KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES","description":"Glycosphingolipid biosynthesis - lacto and neolacto series"} {"geneset":"KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES","description":"Glycosphingolipid biosynthesis - globo series"} {"geneset":"KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES","description":"Glycosphingolipid biosynthesis - ganglio series"} {"geneset":"KEGG_PYRUVATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PYRUVATE_METABOLISM","description":"Pyruvate metabolism"} {"geneset":"KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM","description":"Glyoxylate and dicarboxylate metabolism"} {"geneset":"KEGG_PROPANOATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PROPANOATE_METABOLISM","description":"Propanoate metabolism"} {"geneset":"KEGG_BUTANOATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_BUTANOATE_METABOLISM","description":"Butanoate metabolism"} {"geneset":"KEGG_ONE_CARBON_POOL_BY_FOLATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ONE_CARBON_POOL_BY_FOLATE","description":"One carbon pool by folate"} {"geneset":"KEGG_RIBOFLAVIN_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_RIBOFLAVIN_METABOLISM","description":"Riboflavin metabolism"} {"geneset":"KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM","description":"Nicotinate and nicotinamide metabolism"} {"geneset":"KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS","description":"Pantothenate and CoA biosynthesis"} {"geneset":"KEGG_FOLATE_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_FOLATE_BIOSYNTHESIS","description":"Folate biosynthesis"} {"geneset":"KEGG_RETINOL_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_RETINOL_METABOLISM","description":"Retinol metabolism"} {"geneset":"KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM","description":"Porphyrin and chlorophyll metabolism"} {"geneset":"KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS","description":"Terpenoid backbone biosynthesis"} {"geneset":"KEGG_LIMONENE_AND_PINENE_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_LIMONENE_AND_PINENE_DEGRADATION","description":"Limonene and pinene degradation"} {"geneset":"KEGG_NITROGEN_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_NITROGEN_METABOLISM","description":"Nitrogen metabolism"} {"geneset":"KEGG_SULFUR_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_SULFUR_METABOLISM","description":"Sulfur metabolism"} {"geneset":"KEGG_AMINOACYL_TRNA_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_AMINOACYL_TRNA_BIOSYNTHESIS","description":"Aminoacyl-tRNA biosynthesis"} {"geneset":"KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450","description":"Metabolism of xenobiotics by cytochrome P450"} {"geneset":"KEGG_DRUG_METABOLISM_CYTOCHROME_P450","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_DRUG_METABOLISM_CYTOCHROME_P450","description":"Drug metabolism - cytochrome P450"} {"geneset":"KEGG_DRUG_METABOLISM_OTHER_ENZYMES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_DRUG_METABOLISM_OTHER_ENZYMES","description":"Drug metabolism - other enzymes"} {"geneset":"KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS","description":"Biosynthesis of unsaturated fatty 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{"geneset":"KEGG_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_SPLICEOSOME","description":"Spliceosome"} {"geneset":"KEGG_PROTEASOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PROTEASOME","description":"Proteasome"} {"geneset":"KEGG_PROTEIN_EXPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PROTEIN_EXPORT","description":"Protein export"} {"geneset":"KEGG_PPAR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PPAR_SIGNALING_PATHWAY","description":"PPAR signaling pathway"} {"geneset":"KEGG_BASE_EXCISION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_BASE_EXCISION_REPAIR","description":"Base excision repair"} {"geneset":"KEGG_NUCLEOTIDE_EXCISION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_NUCLEOTIDE_EXCISION_REPAIR","description":"Nucleotide excision repair"} {"geneset":"KEGG_MISMATCH_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_MISMATCH_REPAIR","description":"Mismatch repair"} {"geneset":"KEGG_HOMOLOGOUS_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_HOMOLOGOUS_RECOMBINATION","description":"Homologous recombination"} {"geneset":"KEGG_NON_HOMOLOGOUS_END_JOINING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_NON_HOMOLOGOUS_END_JOINING","description":"Non-homologous end-joining"} {"geneset":"KEGG_MAPK_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_MAPK_SIGNALING_PATHWAY","description":"MAPK signaling pathway"} {"geneset":"KEGG_ERBB_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ERBB_SIGNALING_PATHWAY","description":"ErbB signaling pathway"} {"geneset":"KEGG_CALCIUM_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CALCIUM_SIGNALING_PATHWAY","description":"Calcium signaling pathway"} {"geneset":"KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION","description":"Cytokine-cytokine receptor interaction"} {"geneset":"KEGG_CHEMOKINE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CHEMOKINE_SIGNALING_PATHWAY","description":"Chemokine signaling pathway"} {"geneset":"KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM","description":"Phosphatidylinositol signaling system"} {"geneset":"KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION","description":"Neuroactive ligand-receptor interaction"} {"geneset":"KEGG_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CELL_CYCLE","description":"Cell cycle"} {"geneset":"KEGG_OOCYTE_MEIOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_OOCYTE_MEIOSIS","description":"Oocyte meiosis"} {"geneset":"KEGG_P53_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_P53_SIGNALING_PATHWAY","description":"p53 signaling pathway"} {"geneset":"KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS","description":"Ubiquitin mediated proteolysis"} {"geneset":"KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT","description":"SNARE interactions in vesicular transport"} {"geneset":"KEGG_REGULATION_OF_AUTOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_REGULATION_OF_AUTOPHAGY","description":"Regulation of autophagy"} {"geneset":"KEGG_LYSOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_LYSOSOME","description":"Lysosome"} {"geneset":"KEGG_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ENDOCYTOSIS","description":"Endocytosis"} {"geneset":"KEGG_PEROXISOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PEROXISOME","description":"Peroxisome"} {"geneset":"KEGG_MTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_MTOR_SIGNALING_PATHWAY","description":"mTOR signaling pathway"} {"geneset":"KEGG_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_APOPTOSIS","description":"Apoptosis"} {"geneset":"KEGG_CARDIAC_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CARDIAC_MUSCLE_CONTRACTION","description":"Cardiac muscle contraction"} {"geneset":"KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION","description":"Vascular smooth muscle contraction"} {"geneset":"KEGG_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_WNT_SIGNALING_PATHWAY","description":"Wnt signaling pathway"} {"geneset":"KEGG_DORSO_VENTRAL_AXIS_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_DORSO_VENTRAL_AXIS_FORMATION","description":"Dorso-ventral axis formation"} {"geneset":"KEGG_NOTCH_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_NOTCH_SIGNALING_PATHWAY","description":"Notch signaling pathway"} {"geneset":"KEGG_HEDGEHOG_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_HEDGEHOG_SIGNALING_PATHWAY","description":"Hedgehog signaling pathway"} {"geneset":"KEGG_TGF_BETA_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TGF_BETA_SIGNALING_PATHWAY","description":"TGF-beta signaling pathway"} {"geneset":"KEGG_AXON_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_AXON_GUIDANCE","description":"Axon guidance"} {"geneset":"KEGG_VEGF_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_VEGF_SIGNALING_PATHWAY","description":"VEGF signaling pathway"} {"geneset":"KEGG_FOCAL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_FOCAL_ADHESION","description":"Focal adhesion"} {"geneset":"KEGG_ECM_RECEPTOR_INTERACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ECM_RECEPTOR_INTERACTION","description":"ECM-receptor interaction"} {"geneset":"KEGG_CELL_ADHESION_MOLECULES_CAMS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CELL_ADHESION_MOLECULES_CAMS","description":"Cell adhesion molecules (CAMs)"} {"geneset":"KEGG_ADHERENS_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ADHERENS_JUNCTION","description":"Adherens junction"} {"geneset":"KEGG_TIGHT_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TIGHT_JUNCTION","description":"Tight junction"} {"geneset":"KEGG_GAP_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GAP_JUNCTION","description":"Gap junction"} {"geneset":"KEGG_COMPLEMENT_AND_COAGULATION_CASCADES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_COMPLEMENT_AND_COAGULATION_CASCADES","description":"Complement and coagulation cascades"} {"geneset":"KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION","description":"Antigen processing and presentation"} {"geneset":"KEGG_RENIN_ANGIOTENSIN_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_RENIN_ANGIOTENSIN_SYSTEM","description":"Renin-angiotensin 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{"geneset":"KEGG_HEMATOPOIETIC_CELL_LINEAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_HEMATOPOIETIC_CELL_LINEAGE","description":"Hematopoietic cell lineage"} {"geneset":"KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY","description":"Natural killer cell mediated cytotoxicity"} {"geneset":"KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY","description":"T cell receptor signaling pathway"} {"geneset":"KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY","description":"B cell receptor signaling pathway"} {"geneset":"KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY","description":"Fc epsilon RI signaling pathway"} {"geneset":"KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS","description":"Fc gamma R-mediated phagocytosis"} {"geneset":"KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION","description":"Leukocyte transendothelial migration"} {"geneset":"KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION","description":"Intestinal immune network for IgA production"} {"geneset":"KEGG_CIRCADIAN_RHYTHM_MAMMAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_CIRCADIAN_RHYTHM_MAMMAL","description":"Circadian rhythm - mammal"} {"geneset":"KEGG_LONG_TERM_POTENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_LONG_TERM_POTENTIATION","description":"Long-term potentiation"} {"geneset":"KEGG_NEUROTROPHIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_NEUROTROPHIN_SIGNALING_PATHWAY","description":"Neurotrophin signaling pathway"} {"geneset":"KEGG_LONG_TERM_DEPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_LONG_TERM_DEPRESSION","description":"Long-term depression"} {"geneset":"KEGG_OLFACTORY_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_OLFACTORY_TRANSDUCTION","description":"Olfactory transduction"} {"geneset":"KEGG_TASTE_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TASTE_TRANSDUCTION","description":"Taste transduction"} {"geneset":"KEGG_REGULATION_OF_ACTIN_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_REGULATION_OF_ACTIN_CYTOSKELETON","description":"Regulation of actin cytoskeleton"} {"geneset":"KEGG_INSULIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_INSULIN_SIGNALING_PATHWAY","description":"Insulin signaling pathway"} {"geneset":"KEGG_GNRH_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_GNRH_SIGNALING_PATHWAY","description":"GnRH signaling pathway"} {"geneset":"KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION","description":"Progesterone-mediated oocyte maturation"} {"geneset":"KEGG_MELANOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_MELANOGENESIS","description":"Melanogenesis"} {"geneset":"KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY","description":"Adipocytokine signaling pathway"} {"geneset":"KEGG_TYPE_II_DIABETES_MELLITUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TYPE_II_DIABETES_MELLITUS","description":"Type II diabetes mellitus"} {"geneset":"KEGG_TYPE_I_DIABETES_MELLITUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_TYPE_I_DIABETES_MELLITUS","description":"Type I diabetes mellitus"} {"geneset":"KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG","description":"Maturity onset diabetes of the young"} {"geneset":"KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION","description":"Aldosterone-regulated sodium reabsorption"} {"geneset":"KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION","description":"Vasopressin-regulated water reabsorption"} 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{"geneset":"BIOCARTA_TOLL_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_TOLL_PATHWAY","description":"Toll-Like Receptor Pathway"} {"geneset":"BIOCARTA_TPO_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_TPO_PATHWAY","description":"TPO Signaling Pathway"} {"geneset":"BIOCARTA_CREB_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_CREB_PATHWAY","description":"Transcription factor CREB and its extracellular signals"} {"geneset":"BIOCARTA_CARM1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_CARM1_PATHWAY","description":"Transcription Regulation by Methyltransferase of CARM1"} {"geneset":"BIOCARTA_TFF_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_TFF_PATHWAY","description":"Trefoil Factors Initiate Mucosal Healing"} {"geneset":"BIOCARTA_TRKA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIOCARTA_TRKA_PATHWAY","description":"Trka Receptor Signaling 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{"geneset":"ST_INTERFERON_GAMMA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_INTERFERON_GAMMA_PATHWAY","description":"Interferon gamma pathway."} {"geneset":"ST_WNT_CA2_CYCLIC_GMP_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_WNT_CA2_CYCLIC_GMP_PATHWAY","description":"Wnt/Ca2+/cyclic GMP signaling."} {"geneset":"ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS","description":"Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway."} {"geneset":"ST_TUMOR_NECROSIS_FACTOR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_TUMOR_NECROSIS_FACTOR_PATHWAY","description":"Tumor Necrosis Factor Pathway."} {"geneset":"SA_B_CELL_RECEPTOR_COMPLEXES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_B_CELL_RECEPTOR_COMPLEXES","description":"Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases."} {"geneset":"ST_ERK1_ERK2_MAPK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_ERK1_ERK2_MAPK_PATHWAY","description":"ERK1/ERK2 MAPK Pathway"} {"geneset":"SIG_CD40PATHWAYMAP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIG_CD40PATHWAYMAP","description":"Genes related to CD40 signaling"} {"geneset":"SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES","description":"Genes related to PIP3 signaling in cardiac myocytes"} {"geneset":"SA_CASPASE_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_CASPASE_CASCADE","description":"Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade."} {"geneset":"ST_GA12_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_GA12_PATHWAY","description":"G alpha 12 Pathway"} {"geneset":"ST_G_ALPHA_S_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_G_ALPHA_S_PATHWAY","description":"G alpha s Pathway"} {"geneset":"ST_G_ALPHA_I_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_G_ALPHA_I_PATHWAY","description":"G alpha i Pathway"} {"geneset":"SIG_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIG_CHEMOTAXIS","description":"Genes related to chemotaxis"} {"geneset":"ST_IL_13_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_IL_13_PATHWAY","description":"Interleukin 13 (IL-13) Pathway"} {"geneset":"ST_P38_MAPK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_P38_MAPK_PATHWAY","description":"p38 MAPK Pathway"} {"geneset":"SIG_IL4RECEPTOR_IN_B_LYPHOCYTES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIG_IL4RECEPTOR_IN_B_LYPHOCYTES","description":"Genes related to IL4 rceptor signaling in B lymphocytes"} {"geneset":"WNT_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WNT_SIGNALING","description":"Genes related to Wnt-mediated signal transduction"} {"geneset":"ST_JAK_STAT_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_JAK_STAT_PATHWAY","description":"Jak-STAT Pathway"} {"geneset":"SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES","description":"Genes related to regulation of the actin cytoskeleton"} {"geneset":"ST_GRANULE_CELL_SURVIVAL_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_GRANULE_CELL_SURVIVAL_PATHWAY","description":"Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway."} {"geneset":"ST_ADRENERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_ADRENERGIC","description":"Adrenergic Pathway"} {"geneset":"ST_INTEGRIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_INTEGRIN_SIGNALING_PATHWAY","description":"Integrin Signaling Pathway"} {"geneset":"ST_GAQ_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_GAQ_PATHWAY","description":"G alpha q Pathway"} {"geneset":"ST_GA13_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_GA13_PATHWAY","description":"G alpha 13 Pathway"} {"geneset":"ST_STAT3_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_STAT3_PATHWAY","description":"STAT3 Pathway"} {"geneset":"SA_FAS_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_FAS_SIGNALING","description":"The TNF-type receptor Fas induces apoptosis on ligand binding."} {"geneset":"SA_G1_AND_S_PHASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_G1_AND_S_PHASES","description":"Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition."} {"geneset":"SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES","description":"Genes related to the insulin receptor pathway"} {"geneset":"ST_T_CELL_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_T_CELL_SIGNAL_TRANSDUCTION","description":"T Cell Signal Transduction"} {"geneset":"ST_TYPE_I_INTERFERON_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_TYPE_I_INTERFERON_PATHWAY","description":"Type I Interferon (alpha/beta IFN) Pathway"} {"geneset":"ST_PAC1_RECEPTOR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_PAC1_RECEPTOR_PATHWAY","description":"PAC1 Receptor Pathway"} {"geneset":"SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES","description":"Genes related to PIP3 signaling in B lymphocytes"} {"geneset":"SIG_BCR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIG_BCR_SIGNALING_PATHWAY","description":"Members of the BCR signaling pathway"} {"geneset":"SA_G2_AND_M_PHASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_G2_AND_M_PHASES","description":"Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition."} {"geneset":"ST_B_CELL_ANTIGEN_RECEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_B_CELL_ANTIGEN_RECEPTOR","description":"B Cell Antigen Receptor"} {"geneset":"ST_INTERLEUKIN_4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_INTERLEUKIN_4_PATHWAY","description":"Interleukin 4 (IL-4) Pathway"} {"geneset":"ST_WNT_BETA_CATENIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_WNT_BETA_CATENIN_PATHWAY","description":"Wnt/beta-catenin Pathway"} {"geneset":"SA_MMP_CYTOKINE_CONNECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_MMP_CYTOKINE_CONNECTION","description":"Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix."} {"geneset":"ST_JNK_MAPK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_JNK_MAPK_PATHWAY","description":"JNK MAPK Pathway"} {"geneset":"SA_PROGRAMMED_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_PROGRAMMED_CELL_DEATH","description":"Programmed cell death, or apoptosis, eliminates damaged or unneeded cells."} {"geneset":"ST_FAS_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_FAS_SIGNALING_PATHWAY","description":"Fas Signaling Pathway"} {"geneset":"ST_MYOCYTE_AD_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_MYOCYTE_AD_PATHWAY","description":"Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway."} {"geneset":"SA_PTEN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_PTEN_PATHWAY","description":"PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate."} {"geneset":"SA_REG_CASCADE_OF_CYCLIN_EXPR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_REG_CASCADE_OF_CYCLIN_EXPR","description":"Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases."} {"geneset":"SA_TRKA_RECEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SA_TRKA_RECEPTOR","description":"The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth."} {"geneset":"ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY","description":"PI3K Pathway"} {"geneset":"PID_FANCONI_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_FANCONI_PATHWAY","description":"Fanconi anemia pathway"} {"geneset":"PID_SMAD2_3NUCLEAR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_SMAD2_3NUCLEAR_PATHWAY","description":"Regulation of nuclear SMAD2/3 signaling"} {"geneset":"PID_FCER1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_FCER1_PATHWAY","description":"Fc-epsilon receptor I signaling in mast cells"} {"geneset":"PID_ENDOTHELIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ENDOTHELIN_PATHWAY","description":"Endothelins"} {"geneset":"PID_BCR_5PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_BCR_5PATHWAY","description":"BCR signaling pathway"} {"geneset":"PID_PRL_SIGNALING_EVENTS_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PRL_SIGNALING_EVENTS_PATHWAY","description":"Signaling events mediated by PRL"} {"geneset":"PID_RHOA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RHOA_PATHWAY","description":"RhoA signaling pathway"} {"geneset":"PID_ERBB4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ERBB4_PATHWAY","description":"ErbB4 signaling events"} {"geneset":"PID_AURORA_B_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AURORA_B_PATHWAY","description":"Aurora B signaling"} {"geneset":"PID_LYSOPHOSPHOLIPID_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_LYSOPHOSPHOLIPID_PATHWAY","description":"LPA receptor mediated events"} {"geneset":"PID_INSULIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INSULIN_PATHWAY","description":"Insulin Pathway"} {"geneset":"PID_NOTCH_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_NOTCH_PATHWAY","description":"Notch signaling pathway"} {"geneset":"PID_INTEGRIN1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INTEGRIN1_PATHWAY","description":"Beta1 integrin cell surface interactions"} {"geneset":"PID_P73PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_P73PATHWAY","description":"p73 transcription factor network"} {"geneset":"PID_P38_MKK3_6PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_P38_MKK3_6PATHWAY","description":"p38 MAPK signaling pathway"} {"geneset":"PID_GMCSF_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_GMCSF_PATHWAY","description":"GMCSF-mediated signaling events"} {"geneset":"PID_WNT_NONCANONICAL_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_WNT_NONCANONICAL_PATHWAY","description":"Noncanonical Wnt signaling pathway"} {"geneset":"PID_NFKAPPAB_ATYPICAL_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_NFKAPPAB_ATYPICAL_PATHWAY","description":"Atypical NF-kappaB pathway"} {"geneset":"PID_IL4_2PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL4_2PATHWAY","description":"IL4-mediated signaling events"} {"geneset":"PID_HDAC_CLASSII_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HDAC_CLASSII_PATHWAY","description":"Signaling events mediated by HDAC Class II"} {"geneset":"PID_BETA_CATENIN_DEG_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_BETA_CATENIN_DEG_PATHWAY","description":"Degradation of beta catenin"} {"geneset":"PID_HDAC_CLASSIII_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HDAC_CLASSIII_PATHWAY","description":"Signaling events mediated by HDAC Class III"} {"geneset":"PID_GLYPICAN_1PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_GLYPICAN_1PATHWAY","description":"Glypican 1 network"} {"geneset":"PID_TCR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TCR_PATHWAY","description":"TCR signaling in naïve CD4+ T cells"} {"geneset":"PID_IL27_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL27_PATHWAY","description":"IL27-mediated signaling events"} {"geneset":"PID_NFKAPPAB_CANONICAL_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_NFKAPPAB_CANONICAL_PATHWAY","description":"Canonical NF-kappaB pathway"} {"geneset":"PID_E2F_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_E2F_PATHWAY","description":"E2F transcription factor network"} {"geneset":"PID_ER_NONGENOMIC_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ER_NONGENOMIC_PATHWAY","description":"Plasma membrane estrogen receptor signaling"} {"geneset":"PID_DNA_PK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_DNA_PK_PATHWAY","description":"DNA-PK pathway in nonhomologous end joining"} {"geneset":"PID_HIF2PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HIF2PATHWAY","description":"HIF-2-alpha transcription factor network"} {"geneset":"PID_CD40_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CD40_PATHWAY","description":"CD40/CD40L signaling"} {"geneset":"PID_ATR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ATR_PATHWAY","description":"ATR signaling pathway"} {"geneset":"PID_INTEGRIN_CS_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INTEGRIN_CS_PATHWAY","description":"Integrin family cell surface interactions"} {"geneset":"PID_MET_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_MET_PATHWAY","description":"Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)"} {"geneset":"PID_PTP1B_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PTP1B_PATHWAY","description":"Signaling events mediated by PTP1B"} {"geneset":"PID_INTEGRIN3_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INTEGRIN3_PATHWAY","description":"Beta3 integrin cell surface interactions"} {"geneset":"PID_IL12_2PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL12_2PATHWAY","description":"IL12-mediated signaling events"} {"geneset":"PID_S1P_S1P3_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_S1P_S1P3_PATHWAY","description":"S1P3 pathway"} {"geneset":"PID_LPA4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_LPA4_PATHWAY","description":"LPA4-mediated signaling events"} {"geneset":"PID_AR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AR_PATHWAY","description":"Coregulation of Androgen receptor activity"} {"geneset":"PID_NFAT_TFPATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_NFAT_TFPATHWAY","description":"Calcineurin-regulated NFAT-dependent transcription in lymphocytes"} {"geneset":"PID_EPHB_FWD_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_EPHB_FWD_PATHWAY","description":"EPHB forward signaling"} {"geneset":"PID_AVB3_OPN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AVB3_OPN_PATHWAY","description":"Osteopontin-mediated events"} {"geneset":"PID_S1P_S1P4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_S1P_S1P4_PATHWAY","description":"S1P4 pathway"} {"geneset":"PID_FRA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_FRA_PATHWAY","description":"Validated transcriptional targets of AP1 family members Fra1 and Fra2"} {"geneset":"PID_MYC_ACTIV_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_MYC_ACTIV_PATHWAY","description":"Validated targets of C-MYC transcriptional activation"} {"geneset":"PID_ARF6_TRAFFICKING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ARF6_TRAFFICKING_PATHWAY","description":"Arf6 trafficking events"} {"geneset":"PID_RHOA_REG_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RHOA_REG_PATHWAY","description":"Regulation of RhoA activity"} {"geneset":"PID_REELIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_REELIN_PATHWAY","description":"Reelin signaling pathway"} {"geneset":"PID_PS1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PS1_PATHWAY","description":"Presenilin action in Notch and Wnt signaling"} {"geneset":"PID_ILK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ILK_PATHWAY","description":"Integrin-linked kinase signaling"} {"geneset":"PID_NECTIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_NECTIN_PATHWAY","description":"Nectin adhesion pathway"} {"geneset":"PID_P38_ALPHA_BETA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_P38_ALPHA_BETA_PATHWAY","description":"Regulation of p38-alpha and p38-beta"} {"geneset":"PID_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_WNT_SIGNALING_PATHWAY","description":"Wnt signaling network"} {"geneset":"PID_TRAIL_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TRAIL_PATHWAY","description":"TRAIL signaling pathway"} {"geneset":"PID_CDC42_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CDC42_PATHWAY","description":"CDC42 signaling events"} {"geneset":"PID_RET_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RET_PATHWAY","description":"Signaling events regulated by Ret tyrosine kinase"} {"geneset":"PID_CDC42_REG_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CDC42_REG_PATHWAY","description":"Regulation of CDC42 activity"} {"geneset":"PID_ATM_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ATM_PATHWAY","description":"ATM pathway"} {"geneset":"PID_ARF6_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ARF6_PATHWAY","description":"Arf6 signaling events"} {"geneset":"PID_LKB1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_LKB1_PATHWAY","description":"LKB1 signaling events"} {"geneset":"PID_CD8_TCR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CD8_TCR_PATHWAY","description":"TCR signaling in naïve CD8+ T cells"} {"geneset":"PID_WNT_CANONICAL_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_WNT_CANONICAL_PATHWAY","description":"Canonical Wnt signaling pathway"} {"geneset":"PID_TCPTP_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TCPTP_PATHWAY","description":"Signaling events mediated by TCPTP"} {"geneset":"PID_ANGIOPOIETIN_RECEPTOR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ANGIOPOIETIN_RECEPTOR_PATHWAY","description":"Angiopoietin receptor Tie2-mediated signaling"} {"geneset":"PID_FAS_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_FAS_PATHWAY","description":"FAS (CD95) signaling pathway"} {"geneset":"PID_CIRCADIAN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CIRCADIAN_PATHWAY","description":"Circadian rhythm pathway"} {"geneset":"PID_TXA2PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TXA2PATHWAY","description":"Thromboxane A2 receptor signaling"} {"geneset":"PID_SHP2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_SHP2_PATHWAY","description":"SHP2 signaling"} {"geneset":"PID_HDAC_CLASSI_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HDAC_CLASSI_PATHWAY","description":"Signaling events mediated by HDAC Class I"} {"geneset":"PID_S1P_S1P1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_S1P_S1P1_PATHWAY","description":"S1P1 pathway"} {"geneset":"PID_TELOMERASE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TELOMERASE_PATHWAY","description":"Regulation of Telomerase"} {"geneset":"PID_HNF3B_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HNF3B_PATHWAY","description":"FOXA2 and FOXA3 transcription factor networks"} {"geneset":"PID_NETRIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_NETRIN_PATHWAY","description":"Netrin-mediated signaling events"} {"geneset":"PID_IL1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL1_PATHWAY","description":"IL1-mediated signaling events"} {"geneset":"PID_NFAT_3PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_NFAT_3PATHWAY","description":"Role of Calcineurin-dependent NFAT signaling in lymphocytes"} {"geneset":"PID_REG_GR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_REG_GR_PATHWAY","description":"Glucocorticoid receptor regulatory network"} {"geneset":"PID_CONE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CONE_PATHWAY","description":"Visual signal transduction: Cones"} {"geneset":"PID_INTEGRIN_A9B1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INTEGRIN_A9B1_PATHWAY","description":"Alpha9 beta1 integrin signaling events"} {"geneset":"PID_ERB_GENOMIC_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ERB_GENOMIC_PATHWAY","description":"Validated nuclear estrogen receptor beta network"} {"geneset":"PID_ARF6_DOWNSTREAM_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ARF6_DOWNSTREAM_PATHWAY","description":"Arf6 downstream pathway"} {"geneset":"PID_MTOR_4PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_MTOR_4PATHWAY","description":"mTOR signaling pathway"} {"geneset":"PID_IL2_1PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL2_1PATHWAY","description":"IL2-mediated signaling events"} {"geneset":"PID_CXCR4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CXCR4_PATHWAY","description":"CXCR4-mediated signaling events"} {"geneset":"PID_IGF1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IGF1_PATHWAY","description":"IGF1 pathway"} {"geneset":"PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY","description":"EGF receptor (ErbB1) signaling pathway"} {"geneset":"PID_TNF_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TNF_PATHWAY","description":"TNF receptor signaling pathway"} {"geneset":"PID_PLK1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PLK1_PATHWAY","description":"PLK1 signaling events"} {"geneset":"PID_TCR_RAS_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TCR_RAS_PATHWAY","description":"Ras signaling in the CD4+ TCR pathway"} {"geneset":"PID_IL5_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL5_PATHWAY","description":"IL5-mediated signaling events"} {"geneset":"PID_FOXO_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_FOXO_PATHWAY","description":"FoxO family signaling"} {"geneset":"PID_VEGF_VEGFR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_VEGF_VEGFR_PATHWAY","description":"VEGF and VEGFR signaling network"} {"geneset":"PID_THROMBIN_PAR4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_THROMBIN_PAR4_PATHWAY","description":"PAR4-mediated thrombin signaling events"} {"geneset":"PID_MYC_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_MYC_PATHWAY","description":"C-MYC pathway"} {"geneset":"PID_RANBP2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RANBP2_PATHWAY","description":"Sumoylation by RanBP2 regulates transcriptional repression"} {"geneset":"PID_PI3KCI_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PI3KCI_PATHWAY","description":"Class I PI3K signaling events"} {"geneset":"PID_AJDISS_2PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AJDISS_2PATHWAY","description":"Posttranslational regulation of adherens junction stability and dissassembly"} {"geneset":"PID_IL2_PI3K_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL2_PI3K_PATHWAY","description":"IL2 signaling events mediated by PI3K"} {"geneset":"PID_CERAMIDE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CERAMIDE_PATHWAY","description":"Ceramide signaling pathway"} {"geneset":"PID_P53_DOWNSTREAM_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_P53_DOWNSTREAM_PATHWAY","description":"Direct p53 effectors"} {"geneset":"PID_AR_TF_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AR_TF_PATHWAY","description":"Regulation of Androgen receptor activity"} {"geneset":"PID_P75_NTR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_P75_NTR_PATHWAY","description":"p75(NTR)-mediated signaling"} {"geneset":"PID_S1P_META_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_S1P_META_PATHWAY","description":"Sphingosine 1-phosphate (S1P) pathway"} {"geneset":"PID_ECADHERIN_NASCENT_AJ_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ECADHERIN_NASCENT_AJ_PATHWAY","description":"E-cadherin signaling in the nascent adherens junction"} {"geneset":"PID_INTEGRIN4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INTEGRIN4_PATHWAY","description":"Alpha6 beta4 integrin-ligand interactions"} {"geneset":"PID_AMB2_NEUTROPHILS_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AMB2_NEUTROPHILS_PATHWAY","description":"amb2 Integrin signaling"} {"geneset":"PID_AVB3_INTEGRIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AVB3_INTEGRIN_PATHWAY","description":"Integrins in angiogenesis"} {"geneset":"PID_IFNG_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IFNG_PATHWAY","description":"IFN-gamma pathway"} {"geneset":"PID_RXR_VDR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RXR_VDR_PATHWAY","description":"RXR and RAR heterodimerization with other nuclear receptor"} {"geneset":"PID_LIS1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_LIS1_PATHWAY","description":"Lissencephaly gene (LIS1) in neuronal migration and development"} {"geneset":"PID_ERBB1_DOWNSTREAM_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ERBB1_DOWNSTREAM_PATHWAY","description":"ErbB1 downstream signaling"} {"geneset":"PID_SYNDECAN_4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_SYNDECAN_4_PATHWAY","description":"Syndecan-4-mediated signaling events"} {"geneset":"PID_ATF2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ATF2_PATHWAY","description":"ATF-2 transcription factor network"} {"geneset":"PID_AP1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AP1_PATHWAY","description":"AP-1 transcription factor network"} {"geneset":"PID_INTEGRIN2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INTEGRIN2_PATHWAY","description":"Beta2 integrin cell surface interactions"} {"geneset":"PID_UPA_UPAR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_UPA_UPAR_PATHWAY","description":"Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling"} {"geneset":"PID_ERBB2_ERBB3_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ERBB2_ERBB3_PATHWAY","description":"ErbB2/ErbB3 signaling events"} {"geneset":"PID_FOXM1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_FOXM1_PATHWAY","description":"FOXM1 transcription factor network"} {"geneset":"PID_EPHA_FWDPATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_EPHA_FWDPATHWAY","description":"EPHA forward signaling"} {"geneset":"PID_HIF1A_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HIF1A_PATHWAY","description":"Hypoxic and oxygen homeostasis regulation of HIF-1-alpha"} {"geneset":"PID_BMP_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_BMP_PATHWAY","description":"BMP receptor signaling"} {"geneset":"PID_IL3_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL3_PATHWAY","description":"IL3-mediated signaling events"} {"geneset":"PID_IL6_7_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL6_7_PATHWAY","description":"IL6-mediated signaling events"} {"geneset":"PID_ECADHERIN_KERATINOCYTE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ECADHERIN_KERATINOCYTE_PATHWAY","description":"E-cadherin signaling in keratinocytes"} {"geneset":"PID_ALK1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ALK1_PATHWAY","description":"ALK1 signaling events"} {"geneset":"PID_PDGFRB_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PDGFRB_PATHWAY","description":"PDGFR-beta signaling pathway"} {"geneset":"PID_TRKR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TRKR_PATHWAY","description":"Neurotrophic factor-mediated Trk receptor signaling"} {"geneset":"PID_TCR_JNK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TCR_JNK_PATHWAY","description":"JNK signaling in the CD4+ TCR pathway"} {"geneset":"PID_NEPHRIN_NEPH1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_NEPHRIN_NEPH1_PATHWAY","description":"Nephrin/Neph1 signaling in the kidney podocyte"} {"geneset":"PID_CMYB_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CMYB_PATHWAY","description":"C-MYB transcription factor network"} {"geneset":"PID_IL23_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL23_PATHWAY","description":"IL23-mediated signaling events"} {"geneset":"PID_HIV_NEF_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HIV_NEF_PATHWAY","description":"HIV-1 Nef: Negative effector of Fas and TNF-alpha"} {"geneset":"PID_SYNDECAN_1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_SYNDECAN_1_PATHWAY","description":"Syndecan-1-mediated signaling events"} {"geneset":"PID_P38_MK2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_P38_MK2_PATHWAY","description":"p38 signaling mediated by MAPKAP kinases"} {"geneset":"PID_ERA_GENOMIC_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ERA_GENOMIC_PATHWAY","description":"Validated nuclear estrogen receptor alpha network"} {"geneset":"PID_ERBB_NETWORK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ERBB_NETWORK_PATHWAY","description":"ErbB receptor signaling network"} {"geneset":"PID_ALK2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ALK2_PATHWAY","description":"ALK2 signaling events"} {"geneset":"PID_RHODOPSIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RHODOPSIN_PATHWAY","description":"Visual signal transduction: Rods"} {"geneset":"PID_PDGFRA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PDGFRA_PATHWAY","description":"PDGFR-alpha signaling pathway"} {"geneset":"PID_RETINOIC_ACID_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RETINOIC_ACID_PATHWAY","description":"Retinoic acid receptors-mediated signaling"} {"geneset":"PID_P38_GAMMA_DELTA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_P38_GAMMA_DELTA_PATHWAY","description":"Signaling mediated by p38-gamma and p38-delta"} {"geneset":"PID_IL8_CXCR2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL8_CXCR2_PATHWAY","description":"IL8- and CXCR2-mediated signaling events"} {"geneset":"PID_HEDGEHOG_2PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HEDGEHOG_2PATHWAY","description":"Signaling events mediated by the Hedgehog family"} {"geneset":"PID_INTEGRIN5_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INTEGRIN5_PATHWAY","description":"Beta5 beta6 beta7 and beta8 integrin cell surface interactions"} {"geneset":"PID_AR_NONGENOMIC_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AR_NONGENOMIC_PATHWAY","description":"Nongenotropic Androgen signaling"} {"geneset":"PID_ERBB1_INTERNALIZATION_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ERBB1_INTERNALIZATION_PATHWAY","description":"Internalization of ErbB1"} {"geneset":"PID_HEDGEHOG_GLI_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HEDGEHOG_GLI_PATHWAY","description":"Hedgehog signaling events mediated by Gli proteins"} {"geneset":"PID_CASPASE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CASPASE_PATHWAY","description":"Caspase cascade in apoptosis"} {"geneset":"PID_CXCR3_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CXCR3_PATHWAY","description":"CXCR3-mediated signaling events"} {"geneset":"PID_BETA_CATENIN_NUC_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_BETA_CATENIN_NUC_PATHWAY","description":"Regulation of nuclear beta catenin signaling and target gene transcription"} {"geneset":"PID_VEGFR1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_VEGFR1_PATHWAY","description":"VEGFR1 specific signals"} {"geneset":"PID_SMAD2_3PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_SMAD2_3PATHWAY","description":"Regulation of cytoplasmic and nuclear SMAD2/3 signaling"} {"geneset":"PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY","description":"Signaling mediated by p38-alpha and p38-beta"} {"geneset":"PID_KIT_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_KIT_PATHWAY","description":"Signaling events mediated by Stem cell factor receptor (c-Kit)"} {"geneset":"PID_ECADHERIN_STABILIZATION_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ECADHERIN_STABILIZATION_PATHWAY","description":"Stabilization and expansion of the E-cadherin adherens junction"} {"geneset":"PID_EPO_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_EPO_PATHWAY","description":"EPO signaling pathway"} {"geneset":"PID_IL2_STAT5_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL2_STAT5_PATHWAY","description":"IL2 signaling events mediated by STAT5"} {"geneset":"PID_TCR_CALCIUM_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TCR_CALCIUM_PATHWAY","description":"Calcium signaling in the CD4+ TCR pathway"} {"geneset":"PID_DELTA_NP63_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_DELTA_NP63_PATHWAY","description":"Validated transcriptional targets of deltaNp63 isoforms"} {"geneset":"PID_VEGFR1_2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_VEGFR1_2_PATHWAY","description":"Signaling events mediated by VEGFR1 and VEGFR2"} {"geneset":"PID_THROMBIN_PAR1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_THROMBIN_PAR1_PATHWAY","description":"PAR1-mediated thrombin signaling events"} {"geneset":"PID_A6B1_A6B4_INTEGRIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_A6B1_A6B4_INTEGRIN_PATHWAY","description":"a6b1 and a6b4 Integrin signaling"} {"geneset":"PID_SYNDECAN_2_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_SYNDECAN_2_PATHWAY","description":"Syndecan-2-mediated signaling events"} {"geneset":"PID_RAC1_REG_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RAC1_REG_PATHWAY","description":"Regulation of RAC1 activity"} {"geneset":"PID_AURORA_A_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_AURORA_A_PATHWAY","description":"Aurora A signaling"} {"geneset":"PID_ARF_3PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ARF_3PATHWAY","description":"Arf1 pathway"} {"geneset":"PID_INSULIN_GLUCOSE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INSULIN_GLUCOSE_PATHWAY","description":"Insulin-mediated glucose transport"} {"geneset":"PID_PI3KCI_AKT_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PI3KCI_AKT_PATHWAY","description":"Class I PI3K signaling events mediated by Akt"} {"geneset":"PID_SYNDECAN_3_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_SYNDECAN_3_PATHWAY","description":"Syndecan-3-mediated signaling events"} {"geneset":"PID_IL8_CXCR1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL8_CXCR1_PATHWAY","description":"IL8- and CXCR1-mediated signaling events"} {"geneset":"PID_MYC_REPRESS_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_MYC_REPRESS_PATHWAY","description":"Validated targets of C-MYC transcriptional repression"} {"geneset":"PID_HIF1_TFPATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HIF1_TFPATHWAY","description":"HIF-1-alpha transcription factor network"} {"geneset":"PID_TAP63_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TAP63_PATHWAY","description":"Validated transcriptional targets of TAp63 isoforms"} {"geneset":"PID_EPHRINB_REV_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_EPHRINB_REV_PATHWAY","description":"Ephrin B reverse signaling"} {"geneset":"PID_BARD1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_BARD1_PATHWAY","description":"BARD1 signaling 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{"geneset":"PID_MAPK_TRK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_MAPK_TRK_PATHWAY","description":"Trk receptor signaling mediated by the MAPK pathway"} {"geneset":"PID_PI3K_PLC_TRK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_PI3K_PLC_TRK_PATHWAY","description":"Trk receptor signaling mediated by PI3K and PLC-gamma"} {"geneset":"PID_CD8_TCR_DOWNSTREAM_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_CD8_TCR_DOWNSTREAM_PATHWAY","description":"Downstream signaling in naïve CD8+ T cells"} {"geneset":"PID_EPHA2_FWD_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_EPHA2_FWD_PATHWAY","description":"EPHA2 forward signaling"} {"geneset":"PID_LYMPH_ANGIOGENESIS_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_LYMPH_ANGIOGENESIS_PATHWAY","description":"VEGFR3 signaling in lymphatic endothelium"} {"geneset":"PID_ALPHA_SYNUCLEIN_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_ALPHA_SYNUCLEIN_PATHWAY","description":"Alpha-synuclein signaling"} {"geneset":"PID_FGF_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_FGF_PATHWAY","description":"FGF signaling pathway"} {"geneset":"PID_INTEGRIN_A4B1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_INTEGRIN_A4B1_PATHWAY","description":"Alpha4 beta1 integrin signaling events"} {"geneset":"PID_RAC1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RAC1_PATHWAY","description":"RAC1 signaling pathway"} {"geneset":"PID_RB_1PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_RB_1PATHWAY","description":"Regulation of retinoblastoma protein"} {"geneset":"PID_FAK_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_FAK_PATHWAY","description":"Signaling events mediated by focal adhesion kinase"} {"geneset":"PID_HNF3A_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HNF3A_PATHWAY","description":"FOXA1 transcription factor network"} {"geneset":"PID_TGFBR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_TGFBR_PATHWAY","description":"TGF-beta receptor signaling"} {"geneset":"PID_HES_HEY_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_HES_HEY_PATHWAY","description":"Notch-mediated HES/HEY network"} {"geneset":"PID_IL12_STAT4_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PID_IL12_STAT4_PATHWAY","description":"IL12 signaling mediated by STAT4"} {"geneset":"REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS","description":"Genes involved in Glycogen breakdown (glycogenolysis)"} {"geneset":"REACTOME_TRANSLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSLATION","description":"Genes involved in 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{"geneset":"REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE","description":"Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle"} {"geneset":"REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS","description":"Genes involved in Extrinsic Pathway for Apoptosis"} {"geneset":"REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION","description":"Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation"} {"geneset":"REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS","description":"Genes involved in Apoptotic cleavage of cellular proteins"} {"geneset":"REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION","description":"Genes involved in RNA Polymerase I Transcription Termination"} {"geneset":"REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX","description":"Genes involved in Formation of the ternary complex, and subsequently, the 43S complex"} {"geneset":"REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX","description":"Genes involved in Activation of the pre-replicative complex"} {"geneset":"REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS","description":"Genes involved in Processing of Intronless Pre-mRNAs"} {"geneset":"REACTOME_GAP_JUNCTION_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAP_JUNCTION_DEGRADATION","description":"Genes involved in Gap junction degradation"} {"geneset":"REACTOME_BASE_EXCISION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BASE_EXCISION_REPAIR","description":"Genes involved in Base Excision Repair"} {"geneset":"REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM","description":"Genes involved in Bile acid and bile salt metabolism"} {"geneset":"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL","description":"Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"} {"geneset":"REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS","description":"Genes involved in Recycling of bile acids and salts"} {"geneset":"REACTOME_SIGNALING_BY_RHO_GTPASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_RHO_GTPASES","description":"Genes involved in Signaling by Rho GTPases"} {"geneset":"REACTOME_SIGNALING_BY_WNT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_WNT","description":"Genes involved in Signaling by Wnt"} {"geneset":"REACTOME_METABOLISM_OF_NON_CODING_RNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_NON_CODING_RNA","description":"Genes involved in Metabolism of non-coding RNA"} {"geneset":"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL","description":"Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol"} {"geneset":"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS","description":"Genes involved in Synthesis of bile acids and bile salts"} {"geneset":"REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D","description":"Genes involved in Metabolism of steroid hormones and vitamins A and D"} {"geneset":"REACTOME_ANDROGEN_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANDROGEN_BIOSYNTHESIS","description":"Genes involved in Androgen biosynthesis"} {"geneset":"REACTOME_SIGNALLING_BY_NGF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALLING_BY_NGF","description":"Genes involved in Signalling by NGF"} {"geneset":"REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE","description":"Genes involved in Beta-catenin phosphorylation cascade"} {"geneset":"REACTOME_INSULIN_RECEPTOR_RECYCLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INSULIN_RECEPTOR_RECYCLING","description":"Genes involved in Insulin receptor recycling"} {"geneset":"REACTOME_COPI_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COPI_MEDIATED_TRANSPORT","description":"Genes involved in COPI Mediated Transport"} {"geneset":"REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION","description":"Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression"} {"geneset":"REACTOME_SIGNALING_BY_SCF_KIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_SCF_KIT","description":"Genes involved in Signaling by SCF-KIT"} {"geneset":"REACTOME_DEVELOPMENTAL_BIOLOGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEVELOPMENTAL_BIOLOGY","description":"Genes involved in Developmental Biology"} {"geneset":"REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES","description":"Genes involved in 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{"geneset":"REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION","description":"Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression"} {"geneset":"REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION","description":"Genes involved in Antigen processing-Cross presentation"} {"geneset":"REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING","description":"Genes involved in Growth hormone receptor signaling"} {"geneset":"REACTOME_TRIF_MEDIATED_TLR3_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRIF_MEDIATED_TLR3_SIGNALING","description":"Genes involved in TRIF mediated TLR3 signaling"} {"geneset":"REACTOME_CELL_CELL_COMMUNICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CELL_COMMUNICATION","description":"Genes involved in Cell-Cell communication"} {"geneset":"REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS","description":"Genes involved in ABCA transporters in lipid homeostasis"} {"geneset":"REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY","description":"Genes involved in Endosomal/Vacuolar pathway"} {"geneset":"REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION","description":"Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"} {"geneset":"REACTOME_ER_PHAGOSOME_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ER_PHAGOSOME_PATHWAY","description":"Genes involved in ER-Phagosome pathway"} {"geneset":"REACTOME_MEIOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEIOSIS","description":"Genes involved in Meiosis"} {"geneset":"REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING","description":"Genes involved in Negative regulation of FGFR signaling"} {"geneset":"REACTOME_G0_AND_EARLY_G1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G0_AND_EARLY_G1","description":"Genes involved in G0 and Early G1"} {"geneset":"REACTOME_REGULATION_OF_KIT_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_KIT_SIGNALING","description":"Genes involved in Regulation of KIT signaling"} {"geneset":"REACTOME_MEMBRANE_TRAFFICKING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEMBRANE_TRAFFICKING","description":"Genes involved in Membrane Trafficking"} {"geneset":"REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS","description":"Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters"} {"geneset":"REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL","description":"Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"} {"geneset":"REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE","description":"Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle"} {"geneset":"REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM","description":"Genes involved in Vitamin B5 (pantothenate) metabolism"} {"geneset":"REACTOME_BOTULINUM_NEUROTOXICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BOTULINUM_NEUROTOXICITY","description":"Genes involved in Botulinum neurotoxicity"} {"geneset":"REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS","description":"Genes involved in Metabolism of vitamins and cofactors"} {"geneset":"REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING","description":"Genes involved in trans-Golgi Network Vesicle Budding"} {"geneset":"REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS","description":"Genes involved in Proteolytic cleavage of SNARE complex proteins"} {"geneset":"REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY","description":"Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway"} {"geneset":"REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS","description":"Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins"} {"geneset":"REACTOME_IL_7_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_7_SIGNALING","description":"Genes involved in Interleukin-7 signaling"} {"geneset":"REACTOME_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE","description":"Genes involved in Cell Cycle"} {"geneset":"REACTOME_SIGNALING_BY_ERBB4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ERBB4","description":"Genes involved in Signaling by ERBB4"} {"geneset":"REACTOME_ORC1_REMOVAL_FROM_CHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ORC1_REMOVAL_FROM_CHROMATIN","description":"Genes involved in Orc1 removal from chromatin"} {"geneset":"REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS","description":"Genes involved in O-linked glycosylation of mucins"} {"geneset":"REACTOME_SULFUR_AMINO_ACID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SULFUR_AMINO_ACID_METABOLISM","description":"Genes involved in Sulfur amino acid metabolism"} {"geneset":"REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING","description":"Genes involved in Downregulation of ERBB2:ERBB3 signaling"} {"geneset":"REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES","description":"Genes involved in Antiviral mechanism by IFN-stimulated genes"} {"geneset":"REACTOME_PROLACTIN_RECEPTOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROLACTIN_RECEPTOR_SIGNALING","description":"Genes involved in Prolactin receptor signaling"} {"geneset":"REACTOME_SIGNALING_BY_ERBB2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ERBB2","description":"Genes involved in Signaling by ERBB2"} {"geneset":"REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS","description":"Genes involved in Sphingolipid de novo biosynthesis"} {"geneset":"REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS","description":"Genes involved in Termination of O-glycan biosynthesis"} {"geneset":"REACTOME_DEFENSINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEFENSINS","description":"Genes involved in Defensins"} {"geneset":"REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR","description":"Genes involved in Signaling by constitutively active EGFR"} {"geneset":"REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING","description":"Genes involved in GRB2 events in ERBB2 signaling"} {"geneset":"REACTOME_SIGNALING_BY_EGFR_IN_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_EGFR_IN_CANCER","description":"Genes involved in Signaling by EGFR in Cancer"} {"geneset":"REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS","description":"Genes involved in Membrane binding and targetting of GAG proteins"} {"geneset":"REACTOME_BETA_DEFENSINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BETA_DEFENSINS","description":"Genes involved in Beta defensins"} {"geneset":"REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE","description":"Genes involved in SRP-dependent cotranslational protein targeting to membrane"} {"geneset":"REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING","description":"Genes involved in PI3K events in ERBB4 signaling"} {"geneset":"REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING","description":"Genes involved in SHC1 events in ERBB4 signaling"} {"geneset":"REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING","description":"Genes involved in PI3K events in ERBB2 signaling"} {"geneset":"REACTOME_NUCLEAR_SIGNALING_BY_ERBB4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEAR_SIGNALING_BY_ERBB4","description":"Genes involved in Nuclear signaling by ERBB4"} {"geneset":"REACTOME_GLYCOSPHINGOLIPID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOSPHINGOLIPID_METABOLISM","description":"Genes involved in Glycosphingolipid metabolism"} {"geneset":"REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION","description":"Genes involved in PPARA Activates Gene Expression"} {"geneset":"REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX","description":"Genes involved in Association of licensing factors with the pre-replicative complex"} {"geneset":"REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI","description":"Genes involved in RIP-mediated NFkB activation via DAI"} {"geneset":"REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION","description":"Genes involved in Pre-NOTCH Transcription and Translation"} {"geneset":"REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX","description":"Genes involved in Degradation of the extracellular matrix"} {"geneset":"REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT","description":"Genes involved in Mitochondrial Protein Import"} {"geneset":"REACTOME_SIGNALING_BY_HIPPO","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_HIPPO","description":"Genes involved in Signaling by Hippo"} {"geneset":"REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS","description":"Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus"} {"geneset":"REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR","description":"Genes involved in Trafficking and processing of endosomal TLR"} {"geneset":"REACTOME_SIGNALING_BY_NOTCH4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH4","description":"Genes involved in Signaling by NOTCH4"} {"geneset":"REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR","description":"Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)"} {"geneset":"REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS","description":"Genes involved in Activation of NF-kappaB in B Cells"} {"geneset":"REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION","description":"Genes involved in RORA Activates Circadian Expression"} {"geneset":"REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS","description":"Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers"} {"geneset":"REACTOME_REGULATION_OF_COMPLEMENT_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_COMPLEMENT_CASCADE","description":"Genes involved in 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{"geneset":"REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION","description":"Genes involved in Extracellular matrix organization"} {"geneset":"REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION","description":"Genes involved in NOTCH1 Intracellular Domain Regulates Transcription"} {"geneset":"REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA","description":"Genes involved in Circadian Repression of Expression by REV-ERBA"} {"geneset":"REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI","description":"Genes involved in Pre-NOTCH Processing in Golgi"} {"geneset":"REACTOME_SIGNALING_BY_NOTCH1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH1","description":"Genes involved in Signaling by NOTCH1"} {"geneset":"REACTOME_SIGNALING_BY_NOTCH3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH3","description":"Genes involved in Signaling by NOTCH3"} {"geneset":"REACTOME_TRIGLYCERIDE_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRIGLYCERIDE_BIOSYNTHESIS","description":"Genes involved in Triglyceride Biosynthesis"} {"geneset":"REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE","description":"Genes involved in Insulin receptor signalling cascade"} {"geneset":"REACTOME_ARMS_MEDIATED_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ARMS_MEDIATED_ACTIVATION","description":"Genes involved in ARMS-mediated activation"} {"geneset":"REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS","description":"Genes involved in Prolonged ERK activation events"} {"geneset":"REACTOME_SIGNALLING_TO_RAS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALLING_TO_RAS","description":"Genes involved in Signalling to RAS"} {"geneset":"REACTOME_SIGNALING_BY_BMP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_BMP","description":"Genes involved in Signaling by BMP"} {"geneset":"REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL","description":"Genes involved in Cell surface interactions at the vascular wall"} {"geneset":"REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE","description":"Genes involved in NGF signalling via TRKA from the plasma membrane"} {"geneset":"REACTOME_SIGNALLING_TO_ERKS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALLING_TO_ERKS","description":"Genes involved in Signalling to ERKs"} {"geneset":"REACTOME_P38MAPK_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P38MAPK_EVENTS","description":"Genes involved in p38MAPK events"} {"geneset":"REACTOME_ACYL_CHAIN_REMODELLING_OF_PI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PI","description":"Genes involved in Acyl chain remodelling of PI"} {"geneset":"REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","description":"Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"} {"geneset":"REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING","description":"Genes involved in Downregulation of TGF-beta receptor signaling"} {"geneset":"REACTOME_COLLAGEN_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COLLAGEN_FORMATION","description":"Genes involved in Collagen formation"} {"geneset":"REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION","description":"Genes 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{"geneset":"REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT","description":"Genes involved in p53-Independent G1/S DNA damage checkpoint"} {"geneset":"REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN","description":"Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen"} {"geneset":"REACTOME_ACYL_CHAIN_REMODELLING_OF_PC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PC","description":"Genes involved in Acyl chain remodelling of PC"} {"geneset":"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE","description":"Genes involved in Synthesis of PIPs at the Golgi membrane"} {"geneset":"REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS","description":"Genes involved in TGF-beta receptor signaling activates SMADs"} {"geneset":"REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2","description":"Genes involved in Activated point mutants of FGFR2"} {"geneset":"REACTOME_PHOSPHOLIPID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHOLIPID_METABOLISM","description":"Genes involved in Phospholipid metabolism"} {"geneset":"REACTOME_CS_DS_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CS_DS_DEGRADATION","description":"Genes involved in CS/DS degradation"} {"geneset":"REACTOME_SYNTHESIS_OF_PA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PA","description":"Genes involved in Synthesis of PA"} {"geneset":"REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA","description":"Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha"} {"geneset":"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE","description":"Genes involved in Synthesis of PIPs at the late endosome membrane"} {"geneset":"REACTOME_SYNTHESIS_OF_PE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PE","description":"Genes involved in Synthesis of PE"} {"geneset":"REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK","description":"Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK"} {"geneset":"REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS","description":"Genes involved in Chondroitin sulfate biosynthesis"} {"geneset":"REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION","description":"Genes involved in Hyaluronan uptake and degradation"} {"geneset":"REACTOME_SIGNALING_BY_FGFR1_MUTANTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR1_MUTANTS","description":"Genes involved in Signaling by FGFR1 mutants"} {"geneset":"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE","description":"Genes involved in Synthesis of PIPs at the plasma membrane"} {"geneset":"REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES","description":"Genes involved in The activation of arylsulfatases"} {"geneset":"REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER","description":"Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer"} {"geneset":"REACTOME_HYALURONAN_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HYALURONAN_METABOLISM","description":"Genes involved in Hyaluronan metabolism"} {"geneset":"REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY","description":"Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity"} {"geneset":"REACTOME_KERATAN_SULFATE_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KERATAN_SULFATE_BIOSYNTHESIS","description":"Genes involved in Keratan sulfate biosynthesis"} {"geneset":"REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE","description":"Genes involved in Reversible Hydration of Carbon Dioxide"} {"geneset":"REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS","description":"Genes involved in Signaling by FGFR1 fusion mutants"} {"geneset":"REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM","description":"Genes involved in alpha-linolenic acid (ALA) metabolism"} {"geneset":"REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1","description":"Genes involved in Signaling by activated point mutants of FGFR1"} {"geneset":"REACTOME_PI_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI_METABOLISM","description":"Genes involved in PI Metabolism"} {"geneset":"REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM","description":"Genes involved in Abacavir transport and metabolism"} {"geneset":"REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM","description":"Genes involved in Chondroitin sulfate/dermatan sulfate metabolism"} {"geneset":"REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS","description":"Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis"} {"geneset":"REACTOME_SYNTHESIS_OF_PC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PC","description":"Genes involved in Synthesis of PC"} {"geneset":"REACTOME_HS_GAG_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HS_GAG_BIOSYNTHESIS","description":"Genes involved in HS-GAG biosynthesis"} {"geneset":"REACTOME_SIGNALING_BY_FGFR3_MUTANTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR3_MUTANTS","description":"Genes involved in Signaling by FGFR3 mutants"} {"geneset":"REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM","description":"Genes involved in Keratan sulfate/keratin metabolism"} {"geneset":"REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION","description":"Genes involved in Apoptosis induced DNA fragmentation"} {"geneset":"REACTOME_KERATAN_SULFATE_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KERATAN_SULFATE_DEGRADATION","description":"Genes involved in Keratan sulfate degradation"} {"geneset":"REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM","description":"Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism"} {"geneset":"REACTOME_GLYCOSAMINOGLYCAN_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOSAMINOGLYCAN_METABOLISM","description":"Genes involved in Glycosaminoglycan metabolism"} {"geneset":"REACTOME_ACYL_CHAIN_REMODELLING_OF_PG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PG","description":"Genes involved in Acyl chain remodelling of PG"} {"geneset":"REACTOME_ACYL_CHAIN_REMODELLING_OF_PE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PE","description":"Genes involved in Acyl chain remodelling of PE"} {"geneset":"REACTOME_ACYL_CHAIN_REMODELLING_OF_PS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PS","description":"Genes involved in Acyl chain remodelling of PS"} {"geneset":"REACTOME_SIGNALING_BY_FGFR_MUTANTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR_MUTANTS","description":"Genes 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{"geneset":"REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6","description":"Genes involved in CDK-mediated phosphorylation and removal of Cdc6"} {"geneset":"REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN","description":"Genes involved in Platelet Adhesion to exposed collagen"} {"geneset":"REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS","description":"Genes involved in VEGF ligand-receptor interactions"} {"geneset":"REACTOME_ENOS_ACTIVATION_AND_REGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENOS_ACTIVATION_AND_REGULATION","description":"Genes involved in eNOS activation and regulation"} {"geneset":"REACTOME_MICRORNA_MIRNA_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MICRORNA_MIRNA_BIOGENESIS","description":"Genes involved in MicroRNA (miRNA) Biogenesis"} {"geneset":"REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION","description":"Genes involved in Nuclear Events (kinase and transcription factor activation)"} {"geneset":"REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING","description":"Genes involved in Retrograde neurotrophin signalling"} {"geneset":"REACTOME_ERKS_ARE_INACTIVATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ERKS_ARE_INACTIVATED","description":"Genes involved in ERKs are inactivated"} {"geneset":"REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK","description":"Genes involved in Negative regulation of the PI3K/AKT network"} {"geneset":"REACTOME_PI3K_AKT_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI3K_AKT_ACTIVATION","description":"Genes involved in PI3K/AKT activation"} {"geneset":"REACTOME_REGULATORY_RNA_PATHWAYS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATORY_RNA_PATHWAYS","description":"Genes involved in Regulatory RNA pathways"} {"geneset":"REACTOME_EGFR_DOWNREGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EGFR_DOWNREGULATION","description":"Genes involved in EGFR downregulation"} {"geneset":"REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA","description":"Genes involved in Processing of Capped Intron-Containing Pre-mRNA"} {"geneset":"REACTOME_PECAM1_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PECAM1_INTERACTIONS","description":"Genes involved in PECAM1 interactions"} {"geneset":"REACTOME_TCR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TCR_SIGNALING","description":"Genes involved in TCR signaling"} {"geneset":"REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX","description":"Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex"} {"geneset":"REACTOME_DOWNSTREAM_TCR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNSTREAM_TCR_SIGNALING","description":"Genes involved in Downstream TCR signaling"} {"geneset":"REACTOME_BASIGIN_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BASIGIN_INTERACTIONS","description":"Genes involved in Basigin interactions"} {"geneset":"REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL","description":"Genes involved in AKT phosphorylates targets in the cytosol"} {"geneset":"REACTOME_GAB1_SIGNALOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAB1_SIGNALOSOME","description":"Genes involved in GAB1 signalosome"} {"geneset":"REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING","description":"Genes involved in SHC1 events in EGFR signaling"} {"geneset":"REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S","description":"Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"} {"geneset":"REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS","description":"Genes involved in Phosphorylation of CD3 and TCR zeta chains"} {"geneset":"REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE","description":"Genes involved in Glutamate Neurotransmitter Release Cycle"} {"geneset":"REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE","description":"Genes involved in Translocation of ZAP-70 to Immunological synapse"} {"geneset":"REACTOME_ERK_MAPK_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ERK_MAPK_TARGETS","description":"Genes involved in ERK/MAPK targets"} {"geneset":"REACTOME_TIE2_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TIE2_SIGNALING","description":"Genes involved in Tie2 Signaling"} {"geneset":"REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES","description":"Genes involved in Generation of second messenger molecules"} {"geneset":"REACTOME_GENERIC_TRANSCRIPTION_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GENERIC_TRANSCRIPTION_PATHWAY","description":"Genes involved in Generic Transcription Pathway"} {"geneset":"REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_","description":"Genes involved in Response to elevated platelet cytosolic Ca2+"} {"geneset":"REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM","description":"Genes involved in Transport of Mature Transcript to Cytoplasm"} {"geneset":"REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES","description":"Genes involved in Metabolism of amino acids and derivatives"} {"geneset":"REACTOME_RNA_POL_I_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_TRANSCRIPTION","description":"Genes involved in RNA Polymerase I Transcription"} {"geneset":"REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS","description":"Genes involved in Fatty Acyl-CoA Biosynthesis"} {"geneset":"REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION","description":"Genes involved in E2F-enabled inhibition of pre-replication complex formation"} {"geneset":"REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES","description":"Genes involved in p75NTR recruits signalling complexes"} {"geneset":"REACTOME_BIOLOGICAL_OXIDATIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BIOLOGICAL_OXIDATIONS","description":"Genes involved in Biological oxidations"} {"geneset":"REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR","description":"Genes involved in Regulated proteolysis of p75NTR"} {"geneset":"REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES","description":"Genes involved in Transmission across Chemical Synapses"} {"geneset":"REACTOME_P75NTR_SIGNALS_VIA_NFKB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P75NTR_SIGNALS_VIA_NFKB","description":"Genes involved in p75NTR signals via NF-kB"} {"geneset":"REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS","description":"Genes involved in Caspase-mediated cleavage of cytoskeletal proteins"} {"geneset":"REACTOME_XENOBIOTICS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_XENOBIOTICS","description":"Genes involved in Xenobiotics"} {"geneset":"REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS","description":"Genes involved in Integrin cell surface interactions"} {"geneset":"REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC","description":"Genes involved in Regulation of ornithine decarboxylase (ODC)"} {"geneset":"REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE","description":"Genes involved in Cytochrome P450 - arranged by substrate type"} {"geneset":"REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY","description":"Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway"} {"geneset":"REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS","description":"Genes involved in Apoptotic cleavage of cell adhesion proteins"} {"geneset":"REACTOME_HDL_MEDIATED_LIPID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HDL_MEDIATED_LIPID_TRANSPORT","description":"Genes involved in HDL-mediated lipid transport"} {"geneset":"REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK","description":"Genes involved in NRAGE signals death through JNK"} {"geneset":"REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS","description":"Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"} {"geneset":"REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS","description":"Genes involved in NRIF signals cell death from the nucleus"} {"geneset":"REACTOME_REGULATION_OF_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_APOPTOSIS","description":"Genes involved in Regulation of Apoptosis"} {"geneset":"REACTOME_RNA_POL_II_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_II_TRANSCRIPTION","description":"Genes involved in RNA Polymerase II Transcription"} {"geneset":"REACTOME_NEURONAL_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEURONAL_SYSTEM","description":"Genes involved in Neuronal System"} {"geneset":"REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL","description":"Genes involved in NF-kB is activated and signals survival"} {"geneset":"REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT","description":"Genes involved in Regulation of beta-cell development"} {"geneset":"REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS","description":"Genes involved in Phase 1 - Functionalization of compounds"} {"geneset":"REACTOME_RNA_POL_III_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_TRANSCRIPTION","description":"Genes involved in RNA Polymerase III Transcription"} {"geneset":"REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE","description":"Genes involved in Cell death signalling via NRAGE, NRIF and NADE"} {"geneset":"REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE","description":"Genes involved in Neurotransmitter Release Cycle"} {"geneset":"REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING","description":"Genes involved in p75 NTR receptor-mediated signalling"} {"geneset":"REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE","description":"Genes involved in Amino acid transport across the plasma membrane"} {"geneset":"REACTOME_ENDOGENOUS_STEROLS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENDOGENOUS_STEROLS","description":"Genes involved in Endogenous sterols"} {"geneset":"REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS","description":"Genes involved in Regulation of gene expression in beta cells"} {"geneset":"REACTOME_GLYCOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOLYSIS","description":"Genes involved in Glycolysis"} {"geneset":"REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND","description":"Genes involved in Processive synthesis on the lagging strand"} {"geneset":"REACTOME_PEPTIDE_CHAIN_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PEPTIDE_CHAIN_ELONGATION","description":"Genes involved in Peptide chain elongation"} {"geneset":"REACTOME_COMMON_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COMMON_PATHWAY","description":"Genes involved in Common Pathway"} {"geneset":"REACTOME_MRNA_CAPPING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_CAPPING","description":"Genes involved in mRNA Capping"} {"geneset":"REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION","description":"Genes involved in Mitochondrial Fatty Acid Beta-Oxidation"} {"geneset":"REACTOME_SIGNALING_BY_GPCR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_GPCR","description":"Genes involved in Signaling by GPCR"} {"geneset":"REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS","description":"Genes involved in Peptide ligand-binding receptors"} {"geneset":"REACTOME_METABOLISM_OF_POLYAMINES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_POLYAMINES","description":"Genes involved in Metabolism of polyamines"} {"geneset":"REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS","description":"Genes involved in Class A/1 (Rhodopsin-like receptors)"} {"geneset":"REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY","description":"Genes involved in Notch-HLH transcription pathway"} {"geneset":"REACTOME_INTEGRATION_OF_ENERGY_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTEGRATION_OF_ENERGY_METABOLISM","description":"Genes involved in Integration of energy metabolism"} {"geneset":"REACTOME_CELL_CYCLE_MITOTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE_MITOTIC","description":"Genes involved in Cell Cycle, Mitotic"} {"geneset":"REACTOME_GLUCONEOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCONEOGENESIS","description":"Genes involved in 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{"geneset":"REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION","description":"Genes involved in Cytosolic tRNA aminoacylation"} {"geneset":"REACTOME_CA_DEPENDENT_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CA_DEPENDENT_EVENTS","description":"Genes involved in Ca-dependent events"} {"geneset":"REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE","description":"Genes involved in Acetylcholine Neurotransmitter Release Cycle"} {"geneset":"REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY","description":"Genes involved in Adenylate cyclase activating pathway"} {"geneset":"REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY","description":"Genes involved in Adenylate cyclase inhibitory pathway"} {"geneset":"REACTOME_DARPP_32_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DARPP_32_EVENTS","description":"Genes involved in DARPP-32 events"} {"geneset":"REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES","description":"Genes involved in Chemokine receptors bind chemokines"} {"geneset":"REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES","description":"Genes involved in Loss of Nlp from mitotic centrosomes"} {"geneset":"REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL","description":"Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell"} {"geneset":"REACTOME_CELL_CYCLE_CHECKPOINTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE_CHECKPOINTS","description":"Genes involved in Cell Cycle Checkpoints"} {"geneset":"REACTOME_DIABETES_PATHWAYS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DIABETES_PATHWAYS","description":"Genes involved in Diabetes pathways"} {"geneset":"REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS","description":"Genes involved in p130Cas linkage to MAPK signaling 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{"geneset":"REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS","description":"Genes involved in Acetylcholine Binding And Downstream Events"} {"geneset":"REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT","description":"Genes involved in ABC-family proteins mediated transport"} {"geneset":"REACTOME_TRNA_AMINOACYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRNA_AMINOACYLATION","description":"Genes involved in tRNA Aminoacylation"} {"geneset":"REACTOME_OLFACTORY_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OLFACTORY_SIGNALING_PATHWAY","description":"Genes involved in Olfactory Signaling Pathway"} {"geneset":"REACTOME_STEROID_HORMONES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_STEROID_HORMONES","description":"Genes involved in Steroid hormones"} {"geneset":"REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB","description":"Genes involved in PKA-mediated phosphorylation of CREB"} {"geneset":"REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES","description":"Genes involved in Recruitment of NuMA to mitotic centrosomes"} {"geneset":"REACTOME_AMINE_DERIVED_HORMONES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINE_DERIVED_HORMONES","description":"Genes involved in Amine-derived hormones"} {"geneset":"REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES","description":"Genes involved in Transmembrane transport of small molecules"} {"geneset":"REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING","description":"Genes involved in Integrin alphaIIb beta3 signaling"} {"geneset":"REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY","description":"Genes involved in Nuclear Receptor transcription pathway"} {"geneset":"REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING","description":"Genes involved in Insulin Synthesis and Processing"} {"geneset":"REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_","description":"Genes involved in Cyclin E associated events during G1/S transition"} {"geneset":"REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS","description":"Genes involved in Homologous recombination repair of replication-independent double-strand breaks"} {"geneset":"REACTOME_G1_PHASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G1_PHASE","description":"Genes involved in G1 Phase"} {"geneset":"REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS","description":"Genes involved in Elevation of cytosolic Ca2+ levels"} {"geneset":"REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE","description":"Genes involved in p53-Dependent G1 DNA Damage Response"} {"geneset":"REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER","description":"Genes involved in Transcription-coupled NER (TC-NER)"} {"geneset":"REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING","description":"Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"} {"geneset":"REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION","description":"Genes involved in Glucagon 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{"geneset":"REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS","description":"Genes involved in Hormone ligand-binding receptors"} {"geneset":"REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE","description":"Genes involved in GPVI-mediated activation cascade"} {"geneset":"REACTOME_PROTEIN_FOLDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROTEIN_FOLDING","description":"Genes involved in Protein folding"} {"geneset":"REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC","description":"Genes involved in Formation of tubulin folding intermediates by CCT/TriC"} {"geneset":"REACTOME_PEROXISOMAL_LIPID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PEROXISOMAL_LIPID_METABOLISM","description":"Genes involved in Peroxisomal lipid metabolism"} {"geneset":"REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY","description":"Genes involved in Post-chaperonin tubulin folding pathway"} {"geneset":"REACTOME_STRIATED_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_STRIATED_MUSCLE_CONTRACTION","description":"Genes involved in Striated Muscle Contraction"} {"geneset":"REACTOME_METABOLISM_OF_NUCLEOTIDES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_NUCLEOTIDES","description":"Genes involved in Metabolism of nucleotides"} {"geneset":"REACTOME_AMINE_LIGAND_BINDING_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINE_LIGAND_BINDING_RECEPTORS","description":"Genes involved in Amine ligand-binding receptors"} {"geneset":"REACTOME_METABOLISM_OF_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_PROTEINS","description":"Genes involved in Metabolism of proteins"} {"geneset":"REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION","description":"Genes involved in Downstream signal transduction"} {"geneset":"REACTOME_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MUSCLE_CONTRACTION","description":"Genes involved in Muscle contraction"} {"geneset":"REACTOME_SEROTONIN_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEROTONIN_RECEPTORS","description":"Genes involved in Serotonin receptors"} {"geneset":"REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX","description":"Genes involved in CDC6 association with the ORC:origin complex"} {"geneset":"REACTOME_M_G1_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_M_G1_TRANSITION","description":"Genes involved in M/G1 Transition"} {"geneset":"REACTOME_MRNA_SPLICING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_SPLICING","description":"Genes involved in mRNA Splicing"} {"geneset":"REACTOME_MRNA_SPLICING_MINOR_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_SPLICING_MINOR_PATHWAY","description":"Genes involved in mRNA Splicing - Minor Pathway"} {"geneset":"REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION","description":"Genes involved in 3' -UTR-mediated translational regulation"} {"geneset":"REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA","description":"Genes involved in Processing of Capped Intronless Pre-mRNA"} {"geneset":"REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS","description":"Genes involved in Purine ribonucleoside monophosphate biosynthesis"} {"geneset":"REACTOME_G1_S_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G1_S_TRANSITION","description":"Genes involved in G1/S Transition"} {"geneset":"REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE","description":"Genes involved in Citric acid cycle (TCA cycle)"} {"geneset":"REACTOME_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSCRIPTION","description":"Genes involved in Transcription"} {"geneset":"REACTOME_POL_SWITCHING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POL_SWITCHING","description":"Genes involved in Polymerase switching"} {"geneset":"REACTOME_NUCLEOTIDE_EXCISION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEOTIDE_EXCISION_REPAIR","description":"Genes involved in Nucleotide Excision Repair"} {"geneset":"REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY","description":"Genes involved in Regulation of the Fanconi anemia pathway"} {"geneset":"REACTOME_AXON_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AXON_GUIDANCE","description":"Genes involved in Axon guidance"} {"geneset":"REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S","description":"Genes involved in Activation of Chaperone Genes by XBP1(S)"} {"geneset":"REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1","description":"Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1"} {"geneset":"REACTOME_PERK_REGULATED_GENE_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PERK_REGULATED_GENE_EXPRESSION","description":"Genes involved in PERK regulated gene expression"} {"geneset":"REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS","description":"Genes involved in G alpha (q) signalling events"} {"geneset":"REACTOME_P2Y_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P2Y_RECEPTORS","description":"Genes involved in P2Y receptors"} {"geneset":"REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS","description":"Genes involved in Trafficking of AMPA receptors"} {"geneset":"REACTOME_NCAM1_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NCAM1_INTERACTIONS","description":"Genes involved in NCAM1 interactions"} {"geneset":"REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS","description":"Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)"} {"geneset":"REACTOME_REGULATION_OF_INSULIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_INSULIN_SECRETION","description":"Genes involved in Regulation of Insulin Secretion"} {"geneset":"REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH","description":"Genes involved in NCAM signaling for neurite out-growth"} {"geneset":"REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE","description":"Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline"} {"geneset":"REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS","description":"Genes involved in Nucleotide-like (purinergic) receptors"} {"geneset":"REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA","description":"Genes involved in Activation of Chaperones by ATF6-alpha"} {"geneset":"REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT","description":"Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript"} {"geneset":"REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS","description":"Genes involved in Eicosanoid ligand-binding receptors"} {"geneset":"REACTOME_ACTIVATION_OF_GENES_BY_ATF4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_GENES_BY_ATF4","description":"Genes involved in Activation of Genes by ATF4"} {"geneset":"REACTOME_UNFOLDED_PROTEIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_UNFOLDED_PROTEIN_RESPONSE","description":"Genes involved in Unfolded Protein Response"} {"geneset":"REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS","description":"Genes involved in Class B/2 (Secretin family receptors)"} {"geneset":"REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS","description":"Genes involved in Glucagon-type ligand receptors"} {"geneset":"REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE","description":"Genes involved in Regulation of Insulin Secretion by Acetylcholine"} {"geneset":"REACTOME_G_ALPHA1213_SIGNALLING_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA1213_SIGNALLING_EVENTS","description":"Genes involved in G alpha (12/13) signalling events"} {"geneset":"REACTOME_FANCONI_ANEMIA_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FANCONI_ANEMIA_PATHWAY","description":"Genes involved in Fanconi Anemia pathway"} {"geneset":"REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS","description":"Genes involved in Trafficking of GluR2-containing AMPA receptors"} {"geneset":"REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA","description":"Genes involved in Activation of Chaperone Genes by ATF6-alpha"} {"geneset":"REACTOME_PROSTANOID_LIGAND_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROSTANOID_LIGAND_RECEPTORS","description":"Genes involved in Prostanoid ligand receptors"} {"geneset":"REACTOME_OPSINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OPSINS","description":"Genes involved in Opsins"} {"geneset":"REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_","description":"Genes involved in Formation of RNA Pol II elongation complex"} {"geneset":"REACTOME_MRNA_3_END_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_3_END_PROCESSING","description":"Genes involved in mRNA 3'-end processing"} {"geneset":"REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS","description":"Genes involved in Post-translational modification: synthesis of GPI-anchored proteins"} {"geneset":"REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION","description":"Genes involved in Cyclin A/B1 associated events during G2/M transition"} {"geneset":"REACTOME_ELONGATION_ARREST_AND_RECOVERY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ELONGATION_ARREST_AND_RECOVERY","description":"Genes involved in Elongation arrest and recovery"} {"geneset":"REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT","description":"Genes involved in SLC-mediated transmembrane transport"} {"geneset":"REACTOME_ADP_SIGNALLING_THROUGH_P2RY1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADP_SIGNALLING_THROUGH_P2RY1","description":"Genes involved in ADP signalling through P2Y purinoceptor 1"} {"geneset":"REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA","description":"Genes involved in G beta:gamma signalling through PLC beta"} {"geneset":"REACTOME_CD28_CO_STIMULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CD28_CO_STIMULATION","description":"Genes involved in CD28 co-stimulation"} {"geneset":"REACTOME_GPCR_DOWNSTREAM_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GPCR_DOWNSTREAM_SIGNALING","description":"Genes involved in GPCR downstream signaling"} {"geneset":"REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN","description":"Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin"} {"geneset":"REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS","description":"Genes involved in Adherens junctions interactions"} {"geneset":"REACTOME_CRMPS_IN_SEMA3A_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CRMPS_IN_SEMA3A_SIGNALING","description":"Genes involved in CRMPs in Sema3A signaling"} {"geneset":"REACTOME_OTHER_SEMAPHORIN_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OTHER_SEMAPHORIN_INTERACTIONS","description":"Genes involved in Other semaphorin interactions"} {"geneset":"REACTOME_ACTIVATION_OF_RAC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_RAC","description":"Genes involved in Activation of Rac"} {"geneset":"REACTOME_PURINE_SALVAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PURINE_SALVAGE","description":"Genes involved in Purine salvage"} {"geneset":"REACTOME_G_ALPHA_I_SIGNALLING_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA_I_SIGNALLING_EVENTS","description":"Genes involved in G alpha (i) signalling events"} {"geneset":"REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION","description":"Genes involved in Sema3A PAK dependent Axon repulsion"} {"geneset":"REACTOME_CD28_DEPENDENT_VAV1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CD28_DEPENDENT_VAV1_PATHWAY","description":"Genes involved in CD28 dependent Vav1 pathway"} {"geneset":"REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING","description":"Genes involved in Sema4D in semaphorin signaling"} {"geneset":"REACTOME_SEMAPHORIN_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMAPHORIN_INTERACTIONS","description":"Genes involved in Semaphorin interactions"} {"geneset":"REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE","description":"Genes involved in Sema4D induced cell migration and growth-cone collapse"} {"geneset":"REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION","description":"Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"} {"geneset":"REACTOME_LYSOSOME_VESICLE_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LYSOSOME_VESICLE_BIOGENESIS","description":"Genes involved in Lysosome Vesicle Biogenesis"} {"geneset":"REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA","description":"Genes involved in G beta:gamma signalling through PI3Kgamma"} {"geneset":"REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS","description":"Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds"} {"geneset":"REACTOME_SPHINGOLIPID_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SPHINGOLIPID_METABOLISM","description":"Genes involved in Sphingolipid metabolism"} {"geneset":"REACTOME_PD1_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PD1_SIGNALING","description":"Genes involved in PD-1 signaling"} {"geneset":"REACTOME_G_ALPHA_S_SIGNALLING_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA_S_SIGNALLING_EVENTS","description":"Genes involved in G alpha (s) signalling events"} {"geneset":"REACTOME_CELL_CELL_JUNCTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CELL_JUNCTION_ORGANIZATION","description":"Genes involved in Cell-cell junction organization"} {"geneset":"REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS","description":"Genes involved in G alpha (z) signalling events"} {"geneset":"REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS","description":"Genes involved in Facilitative Na+-independent glucose transporters"} {"geneset":"REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY","description":"Genes involved in Costimulation by the CD28 family"} {"geneset":"REACTOME_SIGNALING_BY_ROBO_RECEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ROBO_RECEPTOR","description":"Genes involved in Signaling by Robo receptor"} {"geneset":"REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING","description":"Genes involved in CD28 dependent PI3K/Akt signaling"} {"geneset":"REACTOME_TIGHT_JUNCTION_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TIGHT_JUNCTION_INTERACTIONS","description":"Genes involved in Tight junction interactions"} {"geneset":"REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING","description":"Genes involved in G-protein beta:gamma signalling"} {"geneset":"REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES","description":"Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides"} {"geneset":"REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS","description":"Genes involved in Golgi Associated Vesicle Biogenesis"} {"geneset":"REACTOME_CTLA4_INHIBITORY_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CTLA4_INHIBITORY_SIGNALING","description":"Genes involved in CTLA4 inhibitory signaling"} {"geneset":"REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX","description":"Genes involved in 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{"geneset":"REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER","description":"Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER"} {"geneset":"REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR","description":"Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor"} {"geneset":"REACTOME_SYNTHESIS_OF_DNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_DNA","description":"Genes involved in Synthesis of DNA"} {"geneset":"REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS","description":"Genes involved in Na+/Cl- dependent neurotransmitter transporters"} {"geneset":"REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE","description":"Genes involved in Formation of Fibrin Clot (Clotting Cascade)"} {"geneset":"REACTOME_DEADENYLATION_OF_MRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEADENYLATION_OF_MRNA","description":"Genes involved in Deadenylation of mRNA"} {"geneset":"REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE","description":"Genes involved in mRNA Decay by 5' to 3' Exoribonuclease"} {"geneset":"REACTOME_SIGNAL_AMPLIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNAL_AMPLIFICATION","description":"Genes involved in Signal amplification"} {"geneset":"REACTOME_ZINC_TRANSPORTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ZINC_TRANSPORTERS","description":"Genes involved in Zinc transporters"} {"geneset":"REACTOME_DOUBLE_STRAND_BREAK_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOUBLE_STRAND_BREAK_REPAIR","description":"Genes involved in Double-Strand Break Repair"} {"geneset":"REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR","description":"Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor"} {"geneset":"REACTOME_METAL_ION_SLC_TRANSPORTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METAL_ION_SLC_TRANSPORTERS","description":"Genes involved in Metal ion SLC transporters"} {"geneset":"REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1","description":"Genes involved in Autodegradation of the E3 ubiquitin ligase COP1"} {"geneset":"REACTOME_SMOOTH_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SMOOTH_MUSCLE_CONTRACTION","description":"Genes involved in Smooth Muscle Contraction"} {"geneset":"REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS","description":"Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events"} {"geneset":"REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS","description":"Genes involved in CREB phosphorylation through the activation of Ras"} {"geneset":"REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS","description":"Genes involved in Post NMDA receptor activation events"} {"geneset":"REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION","description":"Genes involved in Unblocking of NMDA receptor, glutamate binding and activation"} {"geneset":"REACTOME_METABOLISM_OF_MRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_MRNA","description":"Genes involved in Metabolism of mRNA"} {"geneset":"REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE","description":"Genes involved in mRNA Decay by 3' to 5' Exoribonuclease"} {"geneset":"REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS","description":"Genes involved in Bile salt and organic anion SLC transporters"} {"geneset":"REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY","description":"Genes involved in Deadenylation-dependent mRNA decay"} {"geneset":"REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII","description":"Genes involved in CREB phosphorylation through the activation of CaMKII"} {"geneset":"REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR","description":"Genes involved in Thromboxane signalling through TP receptor"} {"geneset":"REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS","description":"Genes involved in Cell-extracellular matrix interactions"} {"geneset":"REACTOME_ADP_SIGNALLING_THROUGH_P2RY12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADP_SIGNALLING_THROUGH_P2RY12","description":"Genes involved in ADP signalling through P2Y purinoceptor 12"} {"geneset":"REACTOME_CELL_JUNCTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_JUNCTION_ORGANIZATION","description":"Genes involved in Cell junction organization"} {"geneset":"REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS","description":"Genes involved in Amine compound SLC transporters"} {"geneset":"REACTOME_PYRUVATE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PYRUVATE_METABOLISM","description":"Genes involved in Pyruvate metabolism"} {"geneset":"REACTOME_PURINE_CATABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PURINE_CATABOLISM","description":"Genes involved in Purine catabolism"} {"geneset":"REACTOME_GLUCOSE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCOSE_TRANSPORT","description":"Genes involved in Glucose transport"} {"geneset":"REACTOME_FRS2_MEDIATED_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FRS2_MEDIATED_CASCADE","description":"Genes involved in FRS2-mediated cascade"} {"geneset":"REACTOME_METABOLISM_OF_RNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_RNA","description":"Genes involved in Metabolism of RNA"} {"geneset":"REACTOME_MITOTIC_G1_G1_S_PHASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_G1_G1_S_PHASES","description":"Genes involved in Mitotic G1-G1/S phases"} {"geneset":"REACTOME_PI_3K_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI_3K_CASCADE","description":"Genes involved in PI-3K cascade"} {"geneset":"REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR","description":"Genes involved in Downstream signaling of activated FGFR"} {"geneset":"REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE","description":"Genes involved in Regulation of mitotic cell cycle"} {"geneset":"REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX","description":"Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex"} {"geneset":"REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1","description":"Genes involved in Regulation of AMPK activity via LKB1"} {"geneset":"REACTOME_MITOTIC_M_M_G1_PHASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_M_M_G1_PHASES","description":"Genes involved in Mitotic M-M/G1 phases"} {"geneset":"REACTOME_MYOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MYOGENESIS","description":"Genes involved in Myogenesis"} {"geneset":"REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE","description":"Genes involved in MAP kinase activation in TLR cascade"} {"geneset":"REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE","description":"Genes involved in Phospholipase C-mediated cascade"} {"geneset":"REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING","description":"Genes involved in Activation of Kainate Receptors upon glutamate binding"} {"geneset":"REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS","description":"Genes involved in Ionotropic activity of Kainate Receptors"} {"geneset":"REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS","description":"Genes involved in Activation of the AP-1 family of transcription factors"} {"geneset":"REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES","description":"Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases"} {"geneset":"REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES","description":"Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates"} {"geneset":"REACTOME_GPCR_LIGAND_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GPCR_LIGAND_BINDING","description":"Genes involved in GPCR ligand binding"} {"geneset":"REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION","description":"Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription"} {"geneset":"REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1","description":"Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"} {"geneset":"REACTOME_SHC_MEDIATED_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC_MEDIATED_CASCADE","description":"Genes involved in SHC-mediated cascade"} {"geneset":"REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS","description":"Genes involved in Thrombin signalling through proteinase activated receptors (PARs)"} {"geneset":"REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK","description":"Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK"} {"geneset":"REACTOME_MITOTIC_G2_G2_M_PHASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_G2_G2_M_PHASES","description":"Genes involved in Mitotic G2-G2/M phases"} {"geneset":"REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK","description":"Genes involved in Regulation of Rheb GTPase activity by AMPK"} {"geneset":"REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION","description":"Genes involved in activated TAK1 mediates p38 MAPK activation"} {"geneset":"REACTOME_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DNA_REPAIR","description":"Genes involved in DNA Repair"} {"geneset":"REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS","description":"Genes involved in Effects of PIP2 hydrolysis"} {"geneset":"REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS","description":"Genes involved in RNA Polymerase II Pre-transcription Events"} {"geneset":"REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS","description":"Genes involved in Role of DCC in regulating apoptosis"} {"geneset":"REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION","description":"Genes involved in Post-translational protein modification"} {"geneset":"REACTOME_CHROMOSOME_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHROMOSOME_MAINTENANCE","description":"Genes involved in Chromosome Maintenance"} {"geneset":"REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE","description":"Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere"} {"geneset":"REACTOME_L1CAM_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_L1CAM_INTERACTIONS","description":"Genes involved in L1CAM interactions"} {"geneset":"REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING","description":"Genes involved in Role of second messengers in netrin-1 signaling"} {"geneset":"REACTOME_SIGNALING_BY_ILS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ILS","description":"Genes involved in Signaling by Interleukins"} {"geneset":"REACTOME_NETRIN1_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NETRIN1_SIGNALING","description":"Genes involved in Netrin-1 signaling"} {"geneset":"REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS","description":"Genes involved in Metabolism of lipids and lipoproteins"} {"geneset":"REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS","description":"Genes involved in Interaction between L1 and Ankyrins"} {"geneset":"REACTOME_SIGNAL_TRANSDUCTION_BY_L1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNAL_TRANSDUCTION_BY_L1","description":"Genes involved in Signal transduction by L1"} {"geneset":"REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM","description":"Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism"} {"geneset":"REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES","description":"Genes involved in Transport of vitamins, nucleosides, and related molecules"} {"geneset":"REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS","description":"Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors"} {"geneset":"REACTOME_RNA_POL_I_PROMOTER_OPENING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_PROMOTER_OPENING","description":"Genes involved in RNA Polymerase I Promoter Opening"} {"geneset":"REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS","description":"Genes involved in Presynaptic nicotinic acetylcholine receptors"} {"geneset":"REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT","description":"Genes involved in Organic cation/anion/zwitterion transport"} {"geneset":"REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING","description":"Genes involved in DCC mediated attractive signaling"} {"geneset":"REACTOME_RECYCLING_PATHWAY_OF_L1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECYCLING_PATHWAY_OF_L1","description":"Genes involved in Recycling pathway of L1"} {"geneset":"REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS","description":"Genes involved in Synthesis of substrates in N-glycan biosythesis"} {"geneset":"REACTOME_RESPIRATORY_ELECTRON_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESPIRATORY_ELECTRON_TRANSPORT","description":"Genes involved in Respiratory electron transport"} {"geneset":"REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION","description":"Genes involved in Asparagine N-linked glycosylation"} {"geneset":"REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX","description":"Genes involved in Assembly of the pre-replicative complex"} {"geneset":"REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN","description":"Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"} {"geneset":"REACTOME_IL1_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL1_SIGNALING","description":"Genes involved in Interleukin-1 signaling"} {"geneset":"REACTOME_GLOBAL_GENOMIC_NER_GG_NER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLOBAL_GENOMIC_NER_GG_NER","description":"Genes involved in Global Genomic NER (GG-NER)"} {"geneset":"REACTOME_CGMP_EFFECTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CGMP_EFFECTS","description":"Genes involved in cGMP effects"} {"geneset":"REACTOME_REGULATION_OF_SIGNALING_BY_CBL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_SIGNALING_BY_CBL","description":"Genes involved in Regulation of signaling by CBL"} {"geneset":"REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION","description":"Genes involved in Amino acid synthesis and interconversion (transamination)"} {"geneset":"REACTOME_CALNEXIN_CALRETICULIN_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CALNEXIN_CALRETICULIN_CYCLE","description":"Genes involved in Calnexin/calreticulin cycle"} {"geneset":"REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP","description":"Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"} {"geneset":"REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS","description":"Genes involved in Passive Transport by Aquaporins"} {"geneset":"REACTOME_NEPHRIN_INTERACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEPHRIN_INTERACTIONS","description":"Genes involved in Nephrin interactions"} {"geneset":"REACTOME_IL_3_5_AND_GM_CSF_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_3_5_AND_GM_CSF_SIGNALING","description":"Genes involved in Interleukin-3, 5 and GM-CSF signaling"} {"geneset":"REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE","description":"Genes involved in Nitric oxide stimulates guanylate cyclase"} {"geneset":"REACTOME_PLATELET_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_HOMEOSTASIS","description":"Genes involved in Platelet homeostasis"} {"geneset":"REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE","description":"Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle"} {"geneset":"REACTOME_PLATELET_SENSITIZATION_BY_LDL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_SENSITIZATION_BY_LDL","description":"Genes involved in Platelet sensitization by LDL"} {"geneset":"REACTOME_AQUAPORIN_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AQUAPORIN_MEDIATED_TRANSPORT","description":"Genes involved in Aquaporin-mediated transport"} {"geneset":"REACTOME_IL_RECEPTOR_SHC_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_RECEPTOR_SHC_SIGNALING","description":"Genes involved in Interleukin receptor SHC signaling"} {"geneset":"REACTOME_RAP1_SIGNALLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RAP1_SIGNALLING","description":"Genes involved in Rap1 signalling"} {"geneset":"REACTOME_PLATELET_CALCIUM_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_CALCIUM_HOMEOSTASIS","description":"Genes involved in Platelet calcium 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{"geneset":"REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION","description":"Genes involved in Incretin Synthesis, Secretion, and Inactivation"} {"geneset":"REACTOME_TRANSPORT_OF_ORGANIC_ANIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_ORGANIC_ANIONS","description":"Genes involved in Transport of organic anions"} {"geneset":"REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1","description":"Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)"} {"geneset":"REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS","description":"Genes involved in Regulation of Water Balance by Renal Aquaporins"} {"geneset":"REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1","description":"Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)"} {"geneset":"REACTOME_IRAK1_RECRUITS_IKK_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IRAK1_RECRUITS_IKK_COMPLEX","description":"Genes involved in IRAK1 recruits IKK complex"} {"geneset":"REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION","description":"Genes involved in TRAF6 mediated IRF7 activation"} {"geneset":"REACTOME_CIRCADIAN_CLOCK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CIRCADIAN_CLOCK","description":"Genes involved in Circadian Clock"} {"geneset":"REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION","description":"Genes involved in TRAF6 mediated NF-kB activation"} {"geneset":"REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION","description":"Genes involved in Factors involved in megakaryocyte development and platelet production"} {"geneset":"REACTOME_REGULATION_OF_IFNG_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_IFNG_SIGNALING","description":"Genes involved in Regulation of IFNG signaling"} {"geneset":"REACTOME_GABA_A_RECEPTOR_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GABA_A_RECEPTOR_ACTIVATION","description":"Genes involved in GABA A receptor activation"} {"geneset":"REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS","description":"Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements"} {"geneset":"REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS","description":"Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"} {"geneset":"REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION","description":"Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"} {"geneset":"REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION","description":"Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"} {"geneset":"REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY","description":"Genes involved in TRAF3-dependent IRF activation pathway"} {"geneset":"REACTOME_GABA_B_RECEPTOR_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GABA_B_RECEPTOR_ACTIVATION","description":"Genes involved in GABA B receptor activation"} {"geneset":"REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10","description":"Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10"} {"geneset":"REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP","description":"Genes involved in Destabilization of mRNA by KSRP"} {"geneset":"REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION","description":"Genes involved in Transport to the Golgi and subsequent modification"} {"geneset":"REACTOME_IRON_UPTAKE_AND_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IRON_UPTAKE_AND_TRANSPORT","description":"Genes involved in 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{"geneset":"REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON","description":"Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"} {"geneset":"REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES","description":"Genes involved in Ion transport by P-type ATPases"} {"geneset":"REACTOME_INTERFERON_ALPHA_BETA_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERFERON_ALPHA_BETA_SIGNALING","description":"Genes involved in Interferon alpha/beta signaling"} {"geneset":"REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING","description":"Genes involved in Advanced glycosylation endproduct receptor signaling"} {"geneset":"REACTOME_GABA_RECEPTOR_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GABA_RECEPTOR_ACTIVATION","description":"Genes involved in GABA receptor activation"} {"geneset":"REACTOME_KINESINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KINESINS","description":"Genes involved in Kinesins"} {"geneset":"REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI","description":"Genes involved in N-glycan antennae elongation in the medial/trans-Golgi"} {"geneset":"REACTOME_REGULATION_OF_IFNA_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_IFNA_SIGNALING","description":"Genes involved in Regulation of IFNA signaling"} {"geneset":"REACTOME_INTERFERON_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERFERON_SIGNALING","description":"Genes involved 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White Adipocyte Differentiation"} {"geneset":"REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT","description":"Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)"} {"geneset":"REACTOME_MEIOTIC_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEIOTIC_RECOMBINATION","description":"Genes involved in Meiotic Recombination"} {"geneset":"REACTOME_IL_2_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_2_SIGNALING","description":"Genes involved in Interleukin-2 signaling"} {"geneset":"REACTOME_IL_6_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_6_SIGNALING","description":"Genes involved in Interleukin-6 signaling"} {"geneset":"REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION","description":"Genes involved in Platelet Aggregation (Plug Formation)"} {"geneset":"REACTOME_SIGNALING_BY_NOTCH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH","description":"Genes involved in Signaling by NOTCH"} {"geneset":"REACTOME_LAGGING_STRAND_SYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LAGGING_STRAND_SYNTHESIS","description":"Genes involved in Lagging Strand Synthesis"} {"geneset":"REACTOME_INTRINSIC_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTRINSIC_PATHWAY","description":"Genes involved in Intrinsic Pathway"} {"geneset":"REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1","description":"Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1"} {"geneset":"REACTOME_ETHANOL_OXIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ETHANOL_OXIDATION","description":"Genes involved in Ethanol oxidation"} {"geneset":"REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS","description":"Genes involved in Synthesis of very long-chain fatty acyl-CoAs"} {"geneset":"REACTOME_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DNA_REPLICATION","description":"Genes involved in DNA Replication"} {"geneset":"REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_","description":"Genes involved in Cleavage of Growing Transcript in the Termination Region"} {"geneset":"REACTOME_PKB_MEDIATED_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PKB_MEDIATED_EVENTS","description":"Genes involved in PKB-mediated events"} {"geneset":"REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION","description":"Genes involved in E2F mediated regulation of DNA replication"} {"geneset":"REACTOME_METABOLISM_OF_CARBOHYDRATES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_CARBOHYDRATES","description":"Genes involved in Metabolism of carbohydrates"} {"geneset":"REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS","description":"Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis"} {"geneset":"REACTOME_SIGNALING_BY_INSULIN_RECEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_INSULIN_RECEPTOR","description":"Genes involved in Signaling by Insulin receptor"} {"geneset":"REACTOME_SIGNAL_ATTENUATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNAL_ATTENUATION","description":"Genes involved in Signal attenuation"} {"geneset":"REACTOME_PURINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PURINE_METABOLISM","description":"Genes involved in Purine metabolism"} {"geneset":"REACTOME_SOS_MEDIATED_SIGNALLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SOS_MEDIATED_SIGNALLING","description":"Genes involved in SOS-mediated signalling"} {"geneset":"REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER","description":"Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter"} {"geneset":"REACTOME_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOSIS","description":"Genes involved in Apoptosis"} {"geneset":"REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT","description":"Genes involved in Lipid digestion, mobilization, and transport"} {"geneset":"REACTOME_HEMOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HEMOSTASIS","description":"Genes involved in Hemostasis"} {"geneset":"REACTOME_INFLUENZA_LIFE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INFLUENZA_LIFE_CYCLE","description":"Genes involved in Influenza Life Cycle"} {"geneset":"REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION","description":"Genes involved in Influenza Viral RNA Transcription and Replication"} {"geneset":"REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY","description":"Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery"} {"geneset":"REACTOME_HIV_INFECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HIV_INFECTION","description":"Genes involved in HIV Infection"} {"geneset":"REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS","description":"Genes involved in Transport of Ribonucleoproteins into the Host Nucleus"} {"geneset":"REACTOME_HIV_LIFE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HIV_LIFE_CYCLE","description":"Genes involved in HIV Life Cycle"} {"geneset":"REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT","description":"Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat"} {"geneset":"REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE","description":"Genes involved in Early Phase of HIV Life Cycle"} {"geneset":"REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS","description":"Genes involved in Host Interactions of HIV factors"} {"geneset":"REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION","description":"Genes involved in RNA Polymerase III Transcription Termination"} {"geneset":"REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_","description":"Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins."} {"geneset":"REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX","description":"Genes involved in Formation of the HIV-1 Early Elongation Complex"} {"geneset":"REACTOME_RAF_MAP_KINASE_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RAF_MAP_KINASE_CASCADE","description":"Genes involved in RAF/MAP kinase cascade"} {"geneset":"REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS","description":"Genes involved in Viral Messenger RNA Synthesis"} {"geneset":"REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE","description":"Genes involved in Late Phase of HIV Life Cycle"} {"geneset":"REACTOME_SHC_MEDIATED_SIGNALLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC_MEDIATED_SIGNALLING","description":"Genes involved in SHC-mediated signalling"} {"geneset":"REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS","description":"Genes involved in Interactions of Vpr with host cellular proteins"} {"geneset":"REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING","description":"Genes involved in Formation of ATP by chemiosmotic coupling"} {"geneset":"REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1","description":"Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"} {"geneset":"REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS","description":"Genes involved in Activation of ATR in response to replication stress"} {"geneset":"REACTOME_UNWINDING_OF_DNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_UNWINDING_OF_DNA","description":"Genes involved in Unwinding of DNA"} {"geneset":"REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS","description":"Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins"} {"geneset":"REACTOME_GLUCURONIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCURONIDATION","description":"Genes involved in Glucuronidation"} {"geneset":"REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C","description":"Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C"} {"geneset":"REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE","description":"Genes involved in MyD88:Mal cascade initiated on plasma membrane"} {"geneset":"REACTOME_INNATE_IMMUNE_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INNATE_IMMUNE_SYSTEM","description":"Genes involved in Innate Immune System"} {"geneset":"REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN","description":"Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein"} {"geneset":"REACTOME_MITOTIC_PROMETAPHASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_PROMETAPHASE","description":"Genes involved in Mitotic Prometaphase"} {"geneset":"REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B","description":"Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B"} {"geneset":"REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1","description":"Genes involved in SCF-beta-TrCP mediated degradation of Emi1"} {"geneset":"REACTOME_LIPOPROTEIN_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LIPOPROTEIN_METABOLISM","description":"Genes involved in Lipoprotein metabolism"} {"geneset":"REACTOME_G1_S_SPECIFIC_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G1_S_SPECIFIC_TRANSCRIPTION","description":"Genes involved in G1/S-Specific Transcription"} {"geneset":"REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS","description":"Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis"} {"geneset":"REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT","description":"Genes involved in Chylomicron-mediated lipid transport"} {"geneset":"REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX","description":"Genes involved in Signaling by TGF-beta Receptor Complex"} {"geneset":"REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE","description":"Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"} {"geneset":"REACTOME_ACTIVATED_TLR4_SIGNALLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_TLR4_SIGNALLING","description":"Genes involved in Activated TLR4 signalling"} {"geneset":"REACTOME_IMMUNE_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IMMUNE_SYSTEM","description":"Genes involved in Immune System"} {"geneset":"REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION","description":"Genes involved in Binding and entry of HIV virion"} {"geneset":"REACTOME_PHOSPHORYLATION_OF_THE_APC_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHORYLATION_OF_THE_APC_C","description":"Genes involved in Phosphorylation of the APC/C"} {"geneset":"REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES","description":"Genes involved in Cytosolic sulfonation of small molecules"} {"geneset":"REACTOME_INTEGRATION_OF_PROVIRUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTEGRATION_OF_PROVIRUS","description":"Genes involved in Integration of provirus"} {"geneset":"REACTOME_GLUTATHIONE_CONJUGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUTATHIONE_CONJUGATION","description":"Genes involved in Glutathione conjugation"} {"geneset":"REACTOME_COMPLEMENT_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COMPLEMENT_CASCADE","description":"Genes involved in 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{"geneset":"REACTOME_RNA_POL_III_CHAIN_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_CHAIN_ELONGATION","description":"Genes involved in RNA Polymerase III Chain Elongation"} {"geneset":"REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS","description":"Genes involved in Voltage gated Potassium channels"} {"geneset":"REACTOME_ADAPTIVE_IMMUNE_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADAPTIVE_IMMUNE_SYSTEM","description":"Genes involved in Adaptive Immune System"} {"geneset":"REACTOME_NOD1_2_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NOD1_2_SIGNALING_PATHWAY","description":"Genes involved in NOD1/2 Signaling Pathway"} {"geneset":"REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM","description":"Genes involved in Cytokine Signaling in Immune system"} {"geneset":"REACTOME_MEIOTIC_SYNAPSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEIOTIC_SYNAPSIS","description":"Genes involved in Meiotic Synapsis"} {"geneset":"REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC","description":"Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC"} {"geneset":"REACTOME_THE_NLRP3_INFLAMMASOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THE_NLRP3_INFLAMMASOME","description":"Genes involved in The NLRP3 inflammasome"} {"geneset":"REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION","description":"Genes involved in Class I MHC mediated antigen processing & presentation"} {"geneset":"REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX","description":"Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex"} {"geneset":"REACTOME_PIP3_ACTIVATES_AKT_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PIP3_ACTIVATES_AKT_SIGNALING","description":"Genes involved in PIP3 activates AKT signaling"} {"geneset":"REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION","description":"Genes involved in Antigen processing: Ubiquitination & Proteasome degradation"} {"geneset":"REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS","description":"Genes involved in Tandem pore domain potassium channels"} {"geneset":"REACTOME_INFLAMMASOMES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INFLAMMASOMES","description":"Genes involved in Inflammasomes"} {"geneset":"REACTOME_POTASSIUM_CHANNELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POTASSIUM_CHANNELS","description":"Genes involved in Potassium Channels"} {"geneset":"REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS","description":"Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways"} {"geneset":"REACTOME_INWARDLY_RECTIFYING_K_CHANNELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INWARDLY_RECTIFYING_K_CHANNELS","description":"Genes involved in Inwardly rectifying K+ channels"} {"geneset":"REACTOME_AMYLOIDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMYLOIDS","description":"Genes involved in Amyloids"} {"geneset":"REACTOME_PACKAGING_OF_TELOMERE_ENDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PACKAGING_OF_TELOMERE_ENDS","description":"Genes involved in Packaging Of Telomere Ends"} {"geneset":"REACTOME_TELOMERE_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TELOMERE_MAINTENANCE","description":"Genes involved in Telomere Maintenance"} {"geneset":"REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION","description":"Genes involved in Platelet activation, signaling and aggregation"} {"geneset":"REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND","description":"Genes involved in Removal of the Flap Intermediate from the C-strand"} {"geneset":"REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS","description":"Genes involved in Creation of C4 and C2 activators"} {"geneset":"REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A","description":"Genes involved in APC-Cdc20 mediated degradation of Nek2A"} {"geneset":"REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT","description":"Genes involved in Initial triggering of complement"} {"geneset":"REACTOME_EXTENSION_OF_TELOMERES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EXTENSION_OF_TELOMERES","description":"Genes involved in Extension of Telomeres"} {"geneset":"REACTOME_G2_M_CHECKPOINTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G2_M_CHECKPOINTS","description":"Genes involved in G2/M Checkpoints"} {"geneset":"REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT","description":"Genes involved in 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{"geneset":"REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY","description":"Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway"} {"geneset":"REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION","description":"Genes involved in FGFR ligand binding and activation"} {"geneset":"REACTOME_CHOLESTEROL_BIOSYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHOLESTEROL_BIOSYNTHESIS","description":"Genes involved in Cholesterol biosynthesis"} {"geneset":"REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION","description":"Genes involved in APOBEC3G mediated resistance to 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{"geneset":"REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G","description":"Genes involved in Vif-mediated degradation of APOBEC3G"} {"geneset":"REACTOME_SIGNALING_BY_FGFR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR","description":"Genes involved in Signaling by FGFR"} {"geneset":"REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE","description":"Genes involved in Digestion of dietary carbohydrate"} {"geneset":"REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION","description":"Genes involved in FGFR1 ligand binding and activation"} {"geneset":"REACTOME_GAP_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAP_JUNCTION_ASSEMBLY","description":"Genes involved in Gap junction assembly"} {"geneset":"REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI","description":"Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)"} {"geneset":"REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION","description":"Genes involved in RNA Polymerase I Transcription Initiation"} {"geneset":"REACTOME_PYRIMIDINE_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PYRIMIDINE_METABOLISM","description":"Genes involved in Pyrimidine metabolism"} {"geneset":"REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS","description":"Genes involved in Intrinsic Pathway for Apoptosis"} {"geneset":"REACTOME_PI3K_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI3K_CASCADE","description":"Genes involved in PI3K Cascade"} {"geneset":"REACTOME_APOPTOTIC_EXECUTION_PHASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOTIC_EXECUTION_PHASE","description":"Genes involved in Apoptotic execution phase"} {"geneset":"REACTOME_SHC_RELATED_EVENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC_RELATED_EVENTS","description":"Genes involved in SHC-related events"} {"geneset":"NAKAMURA_CANCER_MICROENVIRONMENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_CANCER_MICROENVIRONMENT_UP","description":"Genes up-regulated in pancreatic cancer cells grown in orthotopic xenograft tumors compared to those grown in vitro."} {"geneset":"NAKAMURA_CANCER_MICROENVIRONMENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_CANCER_MICROENVIRONMENT_DN","description":"Genes down-regulated in pancreatic cancer cells grown in orthotopic xenograft tumors compared to those grown in vitro."} {"geneset":"WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP","description":"Top up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue."} {"geneset":"WEST_ADRENOCORTICAL_TUMOR_MARKERS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEST_ADRENOCORTICAL_TUMOR_MARKERS_DN","description":"Top down-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue."} {"geneset":"WINTER_HYPOXIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WINTER_HYPOXIA_UP","description":"Genes up-regulated in head and neck tumor samples which clustered around known hypoxia genes."} {"geneset":"WINTER_HYPOXIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WINTER_HYPOXIA_DN","description":"Genes down-regulated in head and neck tumor samples which clustered around known hypoxia genes."} {"geneset":"PARENT_MTOR_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARENT_MTOR_SIGNALING_UP","description":"Genes up-regulated in HepaRG cells (liver cancer) expressing constituvely active form of MTOR [GeneID=2475]."} {"geneset":"PARENT_MTOR_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARENT_MTOR_SIGNALING_DN","description":"Genes down-regulated in HepaRG cells (liver cancer) expressing constituvely active form of MTOR [GeneID=2475]."} {"geneset":"PYEON_HPV_POSITIVE_TUMORS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PYEON_HPV_POSITIVE_TUMORS_UP","description":"Up-regulated genes in cervical carcinoma and head and neck tumors positive for human papilloma virus (HPV) compared to those negative for HPV."} {"geneset":"PYEON_HPV_POSITIVE_TUMORS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PYEON_HPV_POSITIVE_TUMORS_DN","description":"Down-regulated genes in cervical carcinoma and head and neck tumors positive for human papilloma virus (HPV) compared to those negative for HPV."} {"geneset":"NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP","description":"Up-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone."} {"geneset":"NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN","description":"Down-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone."} {"geneset":"PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP","description":"Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes."} {"geneset":"PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN","description":"Down-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes."} {"geneset":"LU_TUMOR_VASCULATURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_TUMOR_VASCULATURE_UP","description":"Genes up-regulated in endothelial cells derived from invasive ovarian cancer tissue."} {"geneset":"LU_TUMOR_VASCULATURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_TUMOR_VASCULATURE_DN","description":"Genes down-regulated in endothelial cells derived from invasive ovarian cancer tissue."} {"geneset":"KORKOLA_EMBRYONAL_CARCINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_EMBRYONAL_CARCINOMA_UP","description":"Genes from the 12p region that were up-regulated in embryonic carcinoma tumors compared to normal testis."} {"geneset":"KORKOLA_EMBRYONAL_CARCINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_EMBRYONAL_CARCINOMA_DN","description":"Genes from the 12p region that were down-regulated in embryonic carcinoma tumors compared to normal tissue."} {"geneset":"KORKOLA_TERATOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_TERATOMA_UP","description":"Genes from the 12p region that up-regulated in teratoma cells compared to normal testis."} {"geneset":"KORKOLA_YOLK_SAC_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_YOLK_SAC_TUMOR_UP","description":"Genes from the 12p region that were up-regulated in yolk sac tumor cells compared to normal testis."} {"geneset":"KORKOLA_CHORIOCARCINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_CHORIOCARCINOMA_UP","description":"Genes from the 12p region that were up-regulated in choriocarcinoma cells compared to normal testis."} {"geneset":"KORKOLA_CHORIOCARCINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_CHORIOCARCINOMA_DN","description":"Genes from the 12p region that were down-regulated in choriocarcinoma cells compared to normal testis."} {"geneset":"KORKOLA_SEMINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_SEMINOMA_UP","description":"Genes from the 12p region that were up-regulated in seminoma tumors compared to normal testis."} {"geneset":"KORKOLA_SEMINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_SEMINOMA_DN","description":"Genes from the 12p region that were down-regulated in seminoma tumors compared to normal testis."} {"geneset":"WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP","description":"Genes up-regulated in rectal cancer patients resistant to radiotherapy (non-responders) relative to the sensitive ones (responders)."} {"geneset":"WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN","description":"Genes down-regulated in rectal cancer patients resistant to radiotherapy (non-responders) relative to the sensitive ones (responders)."} {"geneset":"HOLLMANN_APOPTOSIS_VIA_CD40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLMANN_APOPTOSIS_VIA_CD40_UP","description":"Genes up-regulated in DLBCL (diffuse large B-cell lymphoma) cell lines sensitive to stimulation of CD40 [GeneID=958] relative to the resistant ones."} {"geneset":"HOLLMANN_APOPTOSIS_VIA_CD40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLMANN_APOPTOSIS_VIA_CD40_DN","description":"Genes down-regulated in DLBCL (diffuse large B-cell lymphoma) cell lines sensitive to stimulation of CD40 [GeneID=958] relative to the resistant ones."} {"geneset":"LIU_PROSTATE_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_PROSTATE_CANCER_UP","description":"Genes up-regulated in prostate cancer samples."} {"geneset":"LIU_PROSTATE_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_PROSTATE_CANCER_DN","description":"Genes down-regulated in prostate cancer samples."} {"geneset":"LIU_SOX4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_SOX4_TARGETS_UP","description":"Genes up-regulated in LNCaP cells (prostate cancer) by overexpression of SOX4 [GeneID=6659] and down-regulated by its RNAi knockdown."} {"geneset":"LIU_SOX4_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_SOX4_TARGETS_DN","description":"Genes down-regulated in LNCaP cells (prostate cancer) by overexpression of SOX4 [GeneID=6659] and up-regulated by its RNAi knockdown."} {"geneset":"ONKEN_UVEAL_MELANOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONKEN_UVEAL_MELANOMA_UP","description":"Genes up-regulated in uveal melanoma: class 2 vs class 1 tumors."} {"geneset":"ONKEN_UVEAL_MELANOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONKEN_UVEAL_MELANOMA_DN","description":"Genes down-regulated in uveal melanoma: class 2 vs class 1 tumors."} {"geneset":"BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP","description":"Genes up-regulated in medullary breast cancer (MBC) relative to ductal breast cancer (DBD)."} {"geneset":"BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN","description":"Genes down-regulated in medullary breast cancer (MBC) relative to ductal breast cancer (DBD)."} {"geneset":"SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP","description":"Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive)."} {"geneset":"SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN","description":"Genes down-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive)."} {"geneset":"DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP","description":"'PAX-FKHR signature': genes up-regulated by PAX3- or PAX7-FOXO1 [GeneID=5081;5077;2308] fusion in primary alveolar rhabdomyosarcoma(ARMS) tumors."} {"geneset":"DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN","description":"'PAX-FKHR signature': genes down-regulated by PAX3- or PAX7-FOXO1 [GeneID=5081;5077;2308] fusion in primary alveolar rhabdomyosarcoma(ARMS) tumors."} {"geneset":"FOURNIER_ACINAR_DEVELOPMENT_EARLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOURNIER_ACINAR_DEVELOPMENT_EARLY_UP","description":"Genes up-regulated early in HMEC cells (mammary epithelium) during acinar development in vitro."} {"geneset":"FOURNIER_ACINAR_DEVELOPMENT_EARLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOURNIER_ACINAR_DEVELOPMENT_EARLY_DN","description":"Genes down-regulated early in HMEC cells (mammary epithelium) during acinar development in vitro."} {"geneset":"FOURNIER_ACINAR_DEVELOPMENT_LATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOURNIER_ACINAR_DEVELOPMENT_LATE_UP","description":"Genes up-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro."} {"geneset":"FOURNIER_ACINAR_DEVELOPMENT_LATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOURNIER_ACINAR_DEVELOPMENT_LATE_DN","description":"Genes down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro."} {"geneset":"NAM_FXYD5_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAM_FXYD5_TARGETS_DN","description":"Genes down-regulated in MDA-MB-231 cells (breast cancer) after knockdown of FXYD5 [GeneID=53827] by RNAi."} {"geneset":"FRASOR_TAMOXIFEN_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRASOR_TAMOXIFEN_RESPONSE_UP","description":"Genes preferentially up-regulated in MCF-7 cells (breast cancer) by tamoxifen [PubChem=5376] but not by estradiol or fulvestrant (ICI 182780) [PubChem=5757;3478439]."} {"geneset":"FRASOR_TAMOXIFEN_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRASOR_TAMOXIFEN_RESPONSE_DN","description":"Genes preferentially down-regulated in MCF-7 cells (breast cancer) by tamoxifen [PubChem=5376] but not by estradiol or fulvestrant (ICI 182780) [PubChem=5757;3478439]."} {"geneset":"KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP","description":"Genes up-regulated in glioma cell lines treated with both decitabine [PubChem=451668] and TSA [PubChem=5562]."} {"geneset":"KIM_RESPONSE_TO_TSA_AND_DECITABINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_RESPONSE_TO_TSA_AND_DECITABINE_DN","description":"Genes down-regulated in glioma cell lines treated with both decitabine [PubChem=451668] and TSA [PubChem=5562]."} {"geneset":"SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP","description":"Genes up-regulated in nsopharyngeal carcinoma relative to the normal tissue."} {"geneset":"SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN","description":"Genes down-regulated in nsopharyngeal carcinoma relative to the normal tissue."} {"geneset":"WATANABE_COLON_CANCER_MSI_VS_MSS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WATANABE_COLON_CANCER_MSI_VS_MSS_UP","description":"Up-regulated genes discriminating between MSI (microsatellite instability) and MSS (microsatellite stability) colon cancers."} {"geneset":"WATANABE_COLON_CANCER_MSI_VS_MSS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WATANABE_COLON_CANCER_MSI_VS_MSS_DN","description":"Down-regulated genes discriminating between MSI (microsatellite instability) and MSS (microsatellite stability) colon cancers."} {"geneset":"KOBAYASHI_EGFR_SIGNALING_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOBAYASHI_EGFR_SIGNALING_6HR_UP","description":"Genes up-regulated in H1975 cells (non-small cell lung cancer, NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 6h."} {"geneset":"KOBAYASHI_EGFR_SIGNALING_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOBAYASHI_EGFR_SIGNALING_6HR_DN","description":"Genes down-regulated in H1975 cells (non-small cell lung cancer, NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 6h."} {"geneset":"SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP","description":"Up-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3."} {"geneset":"SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN","description":"Down-regulated genes whose expression correlated with histologic grade of invasive breast cancer tumors: comparison of grade 1 vs grade 3."} {"geneset":"GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_UP","description":"Genes up-regulated in erythroid progenitor cells isolated from bone marrow of patients with Diamond-Blackfan anemia (DBA) and mutated RPS19 [GeneID=6223]."} {"geneset":"GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN","description":"Genes down-regulated in erythroid progenitor cells isolated from bone marrow of patients with Diamond-Blackfan anemia (DBA) and mutated RPS19 [GeneID=6223]."} {"geneset":"GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_UP","description":"Genes up-regulated in myeloid progenitor cells isolated from bone marrow of patients with Diamond-Blackfan anemia (DBA) and mutated RPS19 [GeneID=6223]."} {"geneset":"GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_DN","description":"Genes down-regulated in myeloid progenitor cells isolated from bone marrow of patients with Diamond-Blackfan anemia (DBA) and mutated RPS19 [GeneID=6223]."} {"geneset":"GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_UP","description":"Genes up-regulated in common hematopoietic progenitor cells isolated from bone marrow of patients with Diamond-Blackfan anemia (DBA) and mutated RPS19 [GeneID=6223]."} {"geneset":"GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_DN","description":"Genes down-regulated in common hematopoietic progenitor cells isolated from bone marrow of patients with Diamond-Blackfan anemia (DBA) and mutated RPS19 [GeneID=6223]."} {"geneset":"CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP","description":"Genes up-regulated in CD4+ [GeneID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]."} {"geneset":"CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN","description":"Genes down-regulated in CD4+ [GeneID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]."} {"geneset":"ZERBINI_RESPONSE_TO_SULINDAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZERBINI_RESPONSE_TO_SULINDAC_UP","description":"Selected genes up-regulated in DU145 and PC-3 cells (prostate cancer) after treatment with the NSAID (non-steroid anti-inflammatory drug) sulindac [PubChem=5352]."} {"geneset":"ZERBINI_RESPONSE_TO_SULINDAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZERBINI_RESPONSE_TO_SULINDAC_DN","description":"Selected genes down-regulated in DU145 and PC-3 cells (prostate cancer) after treatment with the NSAID (non-steroid anti-inflammatory drug) sulindac [PubChem=5352]."} {"geneset":"IGARASHI_ATF4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IGARASHI_ATF4_TARGETS_UP","description":"Genes up-regulated in A549 cells (lung cancer) after knockdown of ATF4 [GeneID=468] by RNAi."} {"geneset":"IGARASHI_ATF4_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IGARASHI_ATF4_TARGETS_DN","description":"Genes down-regulated in A549 cells (lung cancer) after knockdown of ATF4 [GeneID=468] by RNAi."} {"geneset":"ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP","description":"Genes up-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]."} {"geneset":"ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN","description":"Genes down-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]."} {"geneset":"DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP","description":"Genes up-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors."} {"geneset":"DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN","description":"Genes down-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors."} {"geneset":"DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP","description":"Genes up-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors."} {"geneset":"DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN","description":"Genes down-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors."} {"geneset":"DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP","description":"Genes up-regulated in RMS cells (rhabdomyosarcoma) expressing PAX3 or PAX7 fusions with FOXO1 [GeneID=5077;5081;2308] compared to the fusion negative cell lines."} {"geneset":"DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN","description":"Genes down-regulated in RMS cells (rhabdomyosarcoma) expressing PAX3 or PAX7 fusions with FOXO1 [GeneID=5077;5081;2308] compared to the fusion negative cell lines."} {"geneset":"SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP","description":"Genes up-regulated in nasopharyngeal carcinoma (NPC) positive for LMP1 [GeneID=9260], a latent gene of Epstein-Barr virus (EBV)."} {"geneset":"SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN","description":"Genes down-regulated in nasopharyngeal carcinoma (NPC) positive for LMP1 [GeneID=9260], a latent gene of Epstein-Barr virus (EBV)."} {"geneset":"TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_UP","description":"Genes up-regulated in normal ductal and normal lobular breast cells."} {"geneset":"TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_DN","description":"Genes down-regulated in normal ductal and normal lobular breast cells."} {"geneset":"TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP","description":"Genes up-regulated in ductal carcinoma vs normal ductal breast cells."} {"geneset":"TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN","description":"Genes down-regulated in ductal carcinoma vs normal ductal breast cells."} {"geneset":"TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP","description":"Genes up-regulated in ductal carcinoma vs normal lobular breast cells."} {"geneset":"TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN","description":"Genes down-regulated in ductal carcinoma vs normal lobular breast cells."} {"geneset":"TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_UP","description":"Genes up-regulated in ductal vs lobular carcinoma breast tumor cells."} {"geneset":"TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_DN","description":"Genes down-regulated in ductal vs lobular carcinoma breast tumor cells."} {"geneset":"TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP","description":"Genes up-regulated in lobular carcinoma vs normal ductal breast cells."} {"geneset":"TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN","description":"Genes down-regulated in lobular carcinoma vs normal ductal breast cells."} {"geneset":"TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP","description":"Genes up-regulated in lobular carcinoma vs normal lobular breast cells."} {"geneset":"TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN","description":"Genes down-regulated in lobular carcinoma vs normal lobular breast cells."} {"geneset":"CHANDRAN_METASTASIS_TOP50_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANDRAN_METASTASIS_TOP50_UP","description":"Top 50 genes up-regulated in metastatic vs primary prostate cancer tumors."} {"geneset":"CHANDRAN_METASTASIS_TOP50_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANDRAN_METASTASIS_TOP50_DN","description":"Top 50 genes down-regulated in metastatic vs primary prostate cancer tumors."} {"geneset":"WILCOX_RESPONSE_TO_PROGESTERONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILCOX_RESPONSE_TO_PROGESTERONE_UP","description":"Genes up-regulated in primary cultures of ovarian surface epithlium cells exposed to progesterone [PubChem=5994] for 5 days."} {"geneset":"WILCOX_RESPONSE_TO_PROGESTERONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILCOX_RESPONSE_TO_PROGESTERONE_DN","description":"Genes down-regulated in primary cultures of ovarian surface epithlium cells exposed to progesterone [PubChem=5994] for 5 days."} {"geneset":"FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP","description":"Genes up-regulated in monocyte-derived dendritic cells (MDDC) after stimulation with galecin-1 (lectin, LGALS1) [GeneID=3956] compared to that with bacterial lipopolysaccharide (LPS)."} {"geneset":"FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN","description":"Genes down-regulated in monocyte-derived dendritic cells (MDDC) after stimulation with galecin-1 (lectin, LGALS1) [GeneID=3956] compared to that with bacterial lipopolysaccharide (LPS)."} {"geneset":"GARY_CD5_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARY_CD5_TARGETS_UP","description":"Genes up-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [GeneID=921] off a plasmid vector."} {"geneset":"GARY_CD5_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARY_CD5_TARGETS_DN","description":"Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [GeneID=921] off a plasmid vector."} {"geneset":"ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP","description":"Genes up-regulated in macrophage by live P.gingivalis."} {"geneset":"ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN","description":"Genes down-regulated in macrophage by live P.gingivalis."} {"geneset":"SAMOLS_TARGETS_OF_KHSV_MIRNAS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAMOLS_TARGETS_OF_KHSV_MIRNAS_UP","description":"Genes up-regulated in 293 cells (embryonic kidney) upon expression of KHSV (Kaposi sarcoma-associated herpesvirus) microRNAs."} {"geneset":"SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN","description":"Genes down-regulated in 293 cells (embryonic kidney) upon expression of KHSV (Kaposi sarcoma-associated herpesvirus) microRNAs."} {"geneset":"HOOI_ST7_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOOI_ST7_TARGETS_UP","description":"Genes up-regulated in PC-3 cells (prostate cancer) stably expressing ST7 [GeneID=7982] off a plasmid vector."} {"geneset":"HOOI_ST7_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOOI_ST7_TARGETS_DN","description":"Genes down-regulated in PC-3 cells (prostate cancer) stably expressing ST7 [GeneID=7982] off a plasmid vector."} {"geneset":"PRAMOONJAGO_SOX4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRAMOONJAGO_SOX4_TARGETS_UP","description":"Genes up-regulated in ACC3 cells (adenoid cystic carcinoma) after knockdown of SOX4 [GeneID=6659] by RNAi."} {"geneset":"PRAMOONJAGO_SOX4_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRAMOONJAGO_SOX4_TARGETS_DN","description":"Genes down-regulated in ACC3 cells (adenoid cystic carcinoma) after knockdown of SOX4 [GeneID=6659] by RNAi."} {"geneset":"PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP","description":"Genes up-regulated in OV-90 cells (ovarian cancer) exposed to ascites which inhibited invasion."} {"geneset":"PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN","description":"Genes down-regulated in OV-90 cells (ovarian cancer) exposed to ascites which inhibited invasion."} {"geneset":"PIEPOLI_LGI1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PIEPOLI_LGI1_TARGETS_UP","description":"Up-regulated genes in U87 cells (glioblastoma multiforme, GBM) engineered to stably express LGI1 [GeneID=9211]."} {"geneset":"PIEPOLI_LGI1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PIEPOLI_LGI1_TARGETS_DN","description":"Down-regulated genes in U87 cells (glioblastoma multiforme, GBM) engineered to stably express LGI1 [GeneID=9211]."} {"geneset":"THUM_SYSTOLIC_HEART_FAILURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THUM_SYSTOLIC_HEART_FAILURE_UP","description":"Genes up-regulated in samples with systolic heart failure compared to normal hearts."} {"geneset":"THUM_SYSTOLIC_HEART_FAILURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THUM_SYSTOLIC_HEART_FAILURE_DN","description":"Genes down-regulated in samples with systolic heart failure compared to normal hearts."} {"geneset":"CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP","description":"Genes up-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [GeneID=5371;5914] compared to normal promyeloblasts."} {"geneset":"CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN","description":"Genes down-regulated in APL (acute promyeolocytic leukemia) blasts expressing PML-RARA fusion [GeneID=5371;5914] compared to normal promyeloblasts."} {"geneset":"CORRE_MULTIPLE_MYELOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CORRE_MULTIPLE_MYELOMA_UP","description":"Genes up-regulated in multiple myeloma (MM) bone marrow mesenchymal stem cells."} {"geneset":"CORRE_MULTIPLE_MYELOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CORRE_MULTIPLE_MYELOMA_DN","description":"Genes down-regulated in multiple myeloma (MM) bone marrow mesenchymal stem cells."} {"geneset":"HUTTMANN_B_CLL_POOR_SURVIVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUTTMANN_B_CLL_POOR_SURVIVAL_UP","description":"Up-regulated genes in B-CLL (B-cell chronic leukemia) patients expressing high levels of ZAP70 and CD38 [GeneID=7535;952], which are associated with poor survival."} {"geneset":"HUTTMANN_B_CLL_POOR_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUTTMANN_B_CLL_POOR_SURVIVAL_DN","description":"Down-regulated genes in B-CLL (B-cell chronic leukemia) patients expressing high levels of ZAP70 and CD38 [GeneID=7535;952], which are associated with poor survival."} {"geneset":"DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP","description":"Genes up-regulated in CD34+ [GeneID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients, compared to those from normal donors."} {"geneset":"DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN","description":"Genes down-regulated in CD34+ [GeneID=947] cells isolated from bone marrow of CML (chronic myelogenous leukemia) patients, compared to those from normal donors."} {"geneset":"CASORELLI_APL_SECONDARY_VS_DE_NOVO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASORELLI_APL_SECONDARY_VS_DE_NOVO_UP","description":"Genes up-regulated in secondary APL (acute promyelocytic leukemia) compared to the de novo tumors."} {"geneset":"CASORELLI_APL_SECONDARY_VS_DE_NOVO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASORELLI_APL_SECONDARY_VS_DE_NOVO_DN","description":"Genes down-regulated in secondary APL (acute promyelocytic leukemia) compared to the de novo tumors."} {"geneset":"DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP","description":"Genes up-regulated in T-PLL cells (T-cell prolymphocytic leukemia) bearing the inv(14)/t(14:14) chromosomal aberration."} {"geneset":"DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN","description":"Genes down-regulated in T-PLL cells (T-cell prolymphocytic leukemia) bearing the inv(14)/t(14:14) chromosomal aberration."} {"geneset":"LIU_CMYB_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_CMYB_TARGETS_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) by overexpression of CMYB [GeneID=4602] off adenovirus vector."} {"geneset":"LIU_CMYB_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_CMYB_TARGETS_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) by overexpression of CMYB [GeneID=4602] off adenovirus vector."} {"geneset":"LIU_VMYB_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_VMYB_TARGETS_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) by overexpression of v-MYB oncogenic varian of CMYB [GeneID=4602] off adenovirus vector."} {"geneset":"LIU_TARGETS_OF_VMYB_VS_CMYB_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_TARGETS_OF_VMYB_VS_CMYB_UP","description":"Genes regulated in the opposite directions by v-MYB (UP) and c-MYB (DN) variants of CMYB [GeneID=4602] overexpressed in primary monocyte cultures off adenoviral vectors."} {"geneset":"LIU_TARGETS_OF_VMYB_VS_CMYB_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_TARGETS_OF_VMYB_VS_CMYB_DN","description":"Gene regulated in the opposite directions by v-MYB (DN) and c-MYB (UP) variants of CMYB [GeneID=4602] overexpressed in primary monocyte cultures off adenoviral vectors."} {"geneset":"CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP","description":"Genes up-regulated in luminal-like breast cancer cell lines compared to the basal-like ones."} {"geneset":"CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN","description":"Genes down-regulated in luminal-like breast cancer cell lines compared to the basal-like ones."} {"geneset":"CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP","description":"Genes up-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones."} {"geneset":"CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN","description":"Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones."} {"geneset":"CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP","description":"Genes up-regulated in basal-like breast cancer cell lines as compared to the mesenchymal-like ones."} {"geneset":"CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN","description":"Genes down-regulated in basal-like breast cancer cell lines as compared to the mesenchymal-like ones."} {"geneset":"DOANE_BREAST_CANCER_CLASSES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DOANE_BREAST_CANCER_CLASSES_UP","description":"Genes up-regulated in ER(-) / PR(-) breast tumors (do not express ESR1 and PGR [GeneID=2099;5241]) with molecular similarity to ER(+) (class A) relative to the rest of the ER(-) / PR(-) samples (class B)."} {"geneset":"DOANE_BREAST_CANCER_CLASSES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DOANE_BREAST_CANCER_CLASSES_DN","description":"Genes down-regulated in ER(-) / PR(-) breast tumors (do not express ESR1 and PGR [GeneID=2099;5241]) with molecular similarity to ER(+) (class A) relative to the rest of the ER(-) / PR(-) samples (class B)."} {"geneset":"DOANE_RESPONSE_TO_ANDROGEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DOANE_RESPONSE_TO_ANDROGEN_UP","description":"Genes up-regulated in MDA-MB-453 cells (class A ER(-) [GeneID=2099] breast cancer) after exposure to the androgen R1881 [PubChem=13766]."} {"geneset":"DOANE_RESPONSE_TO_ANDROGEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DOANE_RESPONSE_TO_ANDROGEN_DN","description":"Genes down-regulated in MDA-MB-453 cells (class A ER(-) [GeneID=2099] breast cancer) after exposure to the androgen R1881 [PubChem=13766]."} {"geneset":"DOANE_BREAST_CANCER_ESR1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DOANE_BREAST_CANCER_ESR1_UP","description":"Genes up-regulated in breast cancer samples positive for ESR1 [GeneID=2099] compared to the ESR1 negative tumors."} {"geneset":"DOANE_BREAST_CANCER_ESR1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DOANE_BREAST_CANCER_ESR1_DN","description":"Genes down-regulated in breast cancer samples positive for ESR1 [GeneID=2099] compared to the ESR1 negative tumors."} {"geneset":"WANG_RESPONSE_TO_ANDROGEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_ANDROGEN_UP","description":"Genes up-regulated in LNCaP cells (prostate cancer) treated with synthetic androgen R1881 [PubChem=13766]."} {"geneset":"WANG_RESPONSE_TO_FORSKOLIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_FORSKOLIN_UP","description":"Genes up-regulated in LNCaP cells (prostate cancer) treated with forskolin [PubChem=47936], an activator of PKA pathway."} {"geneset":"WANG_RESPONSE_TO_FORSKOLIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_FORSKOLIN_DN","description":"Genes down-regulated in LNCaP cells (prostate cancer) treated with forskolin [PubChem=47936], an activator of PKA pathway."} {"geneset":"TIMOFEEVA_GROWTH_STRESS_VIA_STAT1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIMOFEEVA_GROWTH_STRESS_VIA_STAT1_DN","description":"Genes down-regulated in SK-NEP-1 cells (Wilm's tumor ) stably expressing inactivated forms of STAT1 [GeneID=6772] under growth stress (hypoxia or nutritional deprivation)."} {"geneset":"LAIHO_COLORECTAL_CANCER_SERRATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LAIHO_COLORECTAL_CANCER_SERRATED_UP","description":"Genes up-regulated in serrated vs conventional colorectal carcinoma (CRC) samples."} {"geneset":"LAIHO_COLORECTAL_CANCER_SERRATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LAIHO_COLORECTAL_CANCER_SERRATED_DN","description":"Genes down-regulated in serrated vs conventional colorectal carcinoma (CRC) samples."} {"geneset":"BORCZUK_MALIGNANT_MESOTHELIOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BORCZUK_MALIGNANT_MESOTHELIOMA_UP","description":"Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma."} {"geneset":"BORCZUK_MALIGNANT_MESOTHELIOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BORCZUK_MALIGNANT_MESOTHELIOMA_DN","description":"Genes down-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma."} {"geneset":"ROY_WOUND_BLOOD_VESSEL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROY_WOUND_BLOOD_VESSEL_UP","description":"Genes up-regulated in blood vessel cells from wound site."} {"geneset":"ROY_WOUND_BLOOD_VESSEL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROY_WOUND_BLOOD_VESSEL_DN","description":"Genes down-regulated in blood vessel cells from wound site."} {"geneset":"GRABARCZYK_BCL11B_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRABARCZYK_BCL11B_TARGETS_UP","description":"Genes up-regulated in Jurkat cells (transformed T lymphocytes) after knockdown of BCL11B [GeneID=64919] by RNAi."} {"geneset":"GRABARCZYK_BCL11B_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRABARCZYK_BCL11B_TARGETS_DN","description":"Genes down-regulated in Jurkat cells (transformed T lymphocytes) after knockdown of BCL11B [GeneID=64919] by RNAi."} {"geneset":"NEWMAN_ERCC6_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NEWMAN_ERCC6_TARGETS_UP","description":"Genes up-regulated in Cockayne syndrome fibroblasts rescued by expression of ERCC6 [GeneID=2074] off a plasmid vector."} {"geneset":"NEWMAN_ERCC6_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NEWMAN_ERCC6_TARGETS_DN","description":"Genes down-regulated in Cockayne syndrome fibroblasts rescued by expression of ERCC6 [GeneID=2074] off a plasmid vector."} {"geneset":"HORIUCHI_WTAP_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HORIUCHI_WTAP_TARGETS_UP","description":"Genes up-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [GeneID=9589] by RNAi."} {"geneset":"HORIUCHI_WTAP_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HORIUCHI_WTAP_TARGETS_DN","description":"Genes down-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [GeneID=9589] by RNAi."} {"geneset":"GAL_LEUKEMIC_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAL_LEUKEMIC_STEM_CELL_UP","description":"Genes up-regulated in leukemic stem cells (LSC), defined as CD34+CD38- [GeneID=947;952] cells from AML (acute myeloid leukemia patients) compared to the CD34+CD38+ cells."} {"geneset":"GAL_LEUKEMIC_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAL_LEUKEMIC_STEM_CELL_DN","description":"Genes down-regulated in leukemic stem cells (LSC), defined as CD34+CD38- [GeneID=947;952] cells from AML (acute myeloid leukemia patients) compared to the CD34+CD38+ cells."} {"geneset":"CHOI_ATL_CHRONIC_VS_ACUTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHOI_ATL_CHRONIC_VS_ACUTE_DN","description":"Genes down-regulated in adult T-cell leukemia (ATL), chronic vs acute clinical condition."} {"geneset":"BASAKI_YBX1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BASAKI_YBX1_TARGETS_UP","description":"Genes up-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [GeneID=4904] knockdown by RNAi."} {"geneset":"BASAKI_YBX1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BASAKI_YBX1_TARGETS_DN","description":"Genes down-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [GeneID=4904] knockdown by RNAi."} {"geneset":"NOJIMA_SFRP2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOJIMA_SFRP2_TARGETS_UP","description":"Cellular proliferation, growth, apoptosis and Wnt signaling genes up-regulated in SNU638 cells (gastric cancer) by overexpression of SFRP2 [GeneID=6423] off a plasmid vector."} {"geneset":"NOJIMA_SFRP2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOJIMA_SFRP2_TARGETS_DN","description":"Cellular proliferation, growth, apoptosis and Wnt signaling genes down-regulated in SNU638 cells (gastric cancer) by overexpression of SFRP2 [GeneID=6423] off a plasmid vector."} {"geneset":"WIKMAN_ASBESTOS_LUNG_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIKMAN_ASBESTOS_LUNG_CANCER_UP","description":"Genes positively correlated with the asbestos exposure of lung cancer patients."} {"geneset":"WIKMAN_ASBESTOS_LUNG_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIKMAN_ASBESTOS_LUNG_CANCER_DN","description":"Genes negatively correlated with the asbestos exposure of lung cancer patients."} {"geneset":"RODRIGUES_DCC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_DCC_TARGETS_UP","description":"Genes up-regulated in HCT8/S1 cells (colon cancer) which normally lack DCC [GeneID=9423] compared to those stably expressing wild type DCC off a plasmid vector."} {"geneset":"RODRIGUES_DCC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_DCC_TARGETS_DN","description":"Genes down-regulated in HCT8/S1 cells (colon cancer) which normally lack DCC [GeneID=9423] compared to those stably expressing wild type DCC off a plasmid vector."} {"geneset":"RODRIGUES_NTN1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_NTN1_TARGETS_UP","description":"Genes up-regulated in HCT8/S11 cells (colon cancer) engineered to stably express NTN1 [GeneID=1630] off a plasmid vector."} {"geneset":"RODRIGUES_NTN1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_NTN1_TARGETS_DN","description":"Genes down-regulated in HCT8/S11 cells (colon cancer) engineered to stably express NTN1 [GeneID=1630] off a plasmid vector."} {"geneset":"WANG_LMO4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_LMO4_TARGETS_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [GeneID=8543] by a Tet Off system."} {"geneset":"WANG_LMO4_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_LMO4_TARGETS_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [GeneID=8543] by a Tet Off system."} {"geneset":"WANG_CLIM2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_CLIM2_TARGETS_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) engineered to conditionally express a dominant negative form of CLIM2 [GeneID=8861] by a Tet Off system."} {"geneset":"WANG_CLIM2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_CLIM2_TARGETS_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) engineered to conditionally express a dominant negative form of CLIM2 [GeneID=8861] by a Tet Off system."} {"geneset":"VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP","description":"Up-regulated genes distinguishing between two subtypes of gastric cancer: advanced (AGC) and early (EGC)."} {"geneset":"VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_DN","description":"Down-regulated genes distinguishing between two subtypes of gastric cancer: advanced (AGC) and early (EGC)."} {"geneset":"VECCHI_GASTRIC_CANCER_EARLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VECCHI_GASTRIC_CANCER_EARLY_UP","description":"Up-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples."} {"geneset":"VECCHI_GASTRIC_CANCER_EARLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VECCHI_GASTRIC_CANCER_EARLY_DN","description":"Down-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples."} {"geneset":"BARRIER_COLON_CANCER_RECURRENCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BARRIER_COLON_CANCER_RECURRENCE_UP","description":"Up-regulated genes from the 70-gene prognosis predictor for stage 2 colon cancer, based on non-neoplastic mucosa gene expression profiles."} {"geneset":"BARRIER_COLON_CANCER_RECURRENCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BARRIER_COLON_CANCER_RECURRENCE_DN","description":"Down-regulated genes from the 70-gene prognosis predictor for stage 2 colon cancer, based on non-neoplastic mucosa gene expression profiles."} {"geneset":"SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP","description":"Genes up-regulated in circulating endothelial cells (CEC) from cancer patients compared to those from healthy donors."} {"geneset":"SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_DN","description":"Genes down-regulated in circulating endothelial cells (CEC) from cancer patients compared to those from healthy donors."} {"geneset":"SLEBOS_HEAD_AND_NECK_CANCER_WITH_HPV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SLEBOS_HEAD_AND_NECK_CANCER_WITH_HPV_UP","description":"Genes up-regulated in head and neck squamous cell carcinoma (HNSCC) samples positive for HPV compared to the HPV-negative tumors."} {"geneset":"JAEGER_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAEGER_METASTASIS_UP","description":"Genes up-regulated in metastases from malignant melanoma compared to the primary tumors."} {"geneset":"JAEGER_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAEGER_METASTASIS_DN","description":"Genes down-regulated in metastases from malignant melanoma compared to the primary tumors."} {"geneset":"OSMAN_BLADDER_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OSMAN_BLADDER_CANCER_UP","description":"Genes up-regulated in blood samples from bladder cancer patients."} {"geneset":"OSMAN_BLADDER_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OSMAN_BLADDER_CANCER_DN","description":"Genes down-regulated in blood samples from bladder cancer patients."} {"geneset":"GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_UP","description":"Genes up-regulated in non-metastatic breast cancer tumors having type 1 amplification in the 20q13 region; involves ZNF217 [GeneID=7764] locus only."} {"geneset":"GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN","description":"Genes down-regulated in non-metastatic breast cancer tumors having type 1 amplification in the 20q13 region; involves ZNF217 [GeneID=7764] locus only."} {"geneset":"GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP","description":"Genes up-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2, STK6 and ZNF217 [GeneID=4605;6790;7764]"} {"geneset":"GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN","description":"Genes down-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2, STK6 and ZNF217 [GeneID=4605;6790;7764]"} {"geneset":"OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP","description":"Genes up-regulated in hematopoietic stem cells (HSC, CD34+ [GeneID=947]) cultured in a three-dimentional collagen gel compared to the cells grown in suspension."} {"geneset":"OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN","description":"Genes down-regulated in hematopoietic stem cells (HSC, CD34+ [GeneID=947]) cultured in a three-dimentional collagen gel compared to the cells grown in suspension."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_UP","description":"Genes from the yellow module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_DN","description":"Genes from the yellow module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP","description":"Genes from the turquoise module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphocholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN","description":"Genes from the turquoise module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphocholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP","description":"Genes from the red module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_DN","description":"Genes from the red module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP","description":"Genes from the magenta module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_DN","description":"Genes from the magenta module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_LIGHTYELLOW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_LIGHTYELLOW_UP","description":"Genes from the lightyellow module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_LIGHTYELLOW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_LIGHTYELLOW_DN","description":"Genes from the lightyellow module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP","description":"Genes from the green module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_DN","description":"Genes from the green module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP","description":"Genes from the blue module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_DN","description":"Genes from the blue module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP","description":"Genes from the black module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_DN","description":"Genes from the black module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_UP","description":"Genes from the grey module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN","description":"Genes from the grey module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC)."} {"geneset":"RUNNE_GENDER_EFFECT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUNNE_GENDER_EFFECT_UP","description":"Up-regulated genes detecting gender effects in global expression profiling studies."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP","description":"Genes up-rgulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 6h."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN","description":"Genes down-rgulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 6h."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP","description":"Genes up-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 3 days after transduction."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN","description":"Genes down-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 3 days after transduction."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP","description":"Genes up-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 8 days after transduction."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN","description":"Genes down-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 8 days after transduction."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP","description":"Genes up-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 10 days after transduction."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN","description":"Genes down-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 10 days after transduction."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP","description":"Genes up-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 16 days after transduction."} {"geneset":"TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN","description":"Genes down-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 16 days after transduction."} {"geneset":"LOPEZ_MESOTELIOMA_SURVIVAL_TIME_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MESOTELIOMA_SURVIVAL_TIME_UP","description":"Top genes higher expressed in short term mesothelioma survivors."} {"geneset":"LOPEZ_MESOTELIOMA_SURVIVAL_TIME_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MESOTELIOMA_SURVIVAL_TIME_DN","description":"Top genes higher expressed in long term mesothelioma survivors."} {"geneset":"BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_UP","description":"Genes up-regulated in ALL (acute lymphoblastic leukemia) patients who developed t-ML (treatment related myeloid leukemia)."} {"geneset":"BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_DN","description":"Genes down-regulated in ALL (acute lymphoblastic leukemia) patients who developed t-ML (treatment related myeloid leukemia)."} {"geneset":"BILBAN_B_CLL_LPL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILBAN_B_CLL_LPL_UP","description":"Genes up-regulated in B-CLL (B-cell chronic leukemia) samples expressing high levels of LPL [GeneID=4023] compared with those expressing low levels of the gene."} {"geneset":"BILBAN_B_CLL_LPL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILBAN_B_CLL_LPL_DN","description":"Genes down-regulated in B-CLL (B-cell chronic leukemia) samples expressing high levels of LPL [GeneID=4023] compared with those expressing low levels of the gene."} {"geneset":"HOEBEKE_LYMPHOID_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOEBEKE_LYMPHOID_STEM_CELL_UP","description":"Genes up-regulated in the common lymphoid progenitor (CLP, defined as CD34+CD38-CD7+ [GeneID=947;952;924]) compared to a multipotent cord blood cell (defined as CD34+CD38+CD7-)."} {"geneset":"HOEBEKE_LYMPHOID_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOEBEKE_LYMPHOID_STEM_CELL_DN","description":"Genes down-regulated in the common lymphoid progenitor (CLP, defined as CD34+CD38-CD7+ [GeneID=947;952;924]) compared to a multipotent cord blood cell (defined as CD34+CD38+CD7-)."} {"geneset":"PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP","description":"Genes up-regulated in CD38+ [GeneID=952] CLL (chronic lymphocytic leukemia) cells."} {"geneset":"PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN","description":"Genes down-regulated in CD38+ [GeneID=952] CLL (chronic lymphocytic leukemia) cells."} {"geneset":"AKL_HTLV1_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AKL_HTLV1_INFECTION_UP","description":"Genes up-regulated in WE17/10 cells (CD4+ [GeneID=920] T lymphocytes) infected by HTLV1 (and thus displaying low CD7 [GeneID=924]) compared to the uninfected (i.e., CD7+) cells."} {"geneset":"AKL_HTLV1_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AKL_HTLV1_INFECTION_DN","description":"Genes down-regulated in WE17/10 cells (CD4+ [GeneID=920] T lymphocytes) infected by HTLV1 (and thus displaying low CD7 [GeneID=924]) compared to the uninfected (i.e., CD7+) cells."} {"geneset":"RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP","description":"Genes up-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids."} {"geneset":"RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN","description":"Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids."} {"geneset":"MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP","description":"The 'NPM1-mutated signature 1': genes up-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [GeneID=4869] compared to all AML cases with the intact gene."} {"geneset":"MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_DN","description":"The 'NPM1-mutated signature 1': genes down-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [GeneID=4869] compared to all AML cases with the intact gene."} {"geneset":"MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP","description":"The 'NPM1-mutated signature 2': genes up-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [GeneID=4869] compared to the AML cases with the intact gene and without recurring cytogenetic anomalities or M7 phenotype."} {"geneset":"MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_DN","description":"The 'NPM1-mutated signature 2': genes down-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [GeneID=4869] compared to the AML cases with the intact gene and without recurring cytogenetic anomalities or M7 phenotype."} {"geneset":"MULLIGHAN_MLL_SIGNATURE_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_MLL_SIGNATURE_1_UP","description":"The 'MLL signature 1': genes up-regulated in pediatric AML (acute myeloid leukemia) with rearranged MLL [GeneID=4297] compared to all AML cases with the intact gene."} {"geneset":"MULLIGHAN_MLL_SIGNATURE_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_MLL_SIGNATURE_1_DN","description":"The 'MLL signature 1': genes down-regulated in pediatric AML (acute myeloid leukemia) with rearranged MLL [GeneID=4297] compared to all AML cases with the intact gene."} {"geneset":"MULLIGHAN_MLL_SIGNATURE_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_MLL_SIGNATURE_2_UP","description":"The 'MLL signature 2': genes up-regulated in pediatric AML (acute myeloid leukemia) with rearranged MLL [GeneID=4297] compared to the AML cases with intact MLL and NPM1 [GeneID=4869]."} {"geneset":"MULLIGHAN_MLL_SIGNATURE_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_MLL_SIGNATURE_2_DN","description":"The 'MLL signature 2': genes down-regulated in pediatric AML (acute myeloid leukemia) with rearranged MLL [GeneID=4297] compared to the AML cases with intact MLL and NPM1 [GeneID=4869]."} {"geneset":"MULLIGHAN_NPM1_SIGNATURE_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_NPM1_SIGNATURE_3_UP","description":"The 'NPM1 signature 3': genes up-regulated in pediatric AML (acute myeloid leukemia) with mutated NPM1 [GeneID=4869] compared to the AML cases with intact NPM1 and MLL [GeneID=4297]."} {"geneset":"MULLIGHAN_NPM1_SIGNATURE_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGHAN_NPM1_SIGNATURE_3_DN","description":"The 'NPM1 signature 3': genes down-regulated in pediatric AML (acute myeloid leukemia) with mutated NPM1 [GeneID=4869] compared to the AML cases with intact NPM1 and MLL [GeneID=4297]."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_UP","description":"Genes up-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing granulocytes."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_DN","description":"Genes down-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing granulocytes."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP","description":"Genes up-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [GeneID=861;862] fusion."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN","description":"Genes down-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [GeneID=861;862] fusion."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP","description":"Genes up-regulated in granulocytes by RUNX1-RUNX1T1 [GeneID=861;862] fusion."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_DN","description":"Genes down-regulated in granulocytes by RUNX1-RUNX1T1 [GeneID=861;862] fusion."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP","description":"Genes up-regulated in monocytes by RUNX1-RUNX1T1 [GeneID=861;862] fusion."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_DN","description":"Genes down-regulated in monocytes by RUNX1-RUNX1T1 [GeneID=861;862] fusion."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP","description":"Genes up-regulated in erythroid lineage cells by RUNX1-RUNX1T1 [GeneID=861;862] fusion ."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_DN","description":"Genes down-regulated in erythroid lineage cells by RUNX1-RUNX1T1 [GeneID=861;862] fusion ."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP","description":"Genes up-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing monocytes."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_DN","description":"Genes down-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing monocytes."} {"geneset":"TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP","description":"Genes up-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing erythroid lineage."} {"geneset":"LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_UP","description":"Genes higher expressed in the worst 25 mesothelioma survivors compared to the 25 best ones."} {"geneset":"LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_DN","description":"Genes higher expressed in the best 25 mesothelioma survivors compared to the 25 worst ones."} {"geneset":"PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP","description":"Genes up-regulated in unstable ateroslerotic plaques compared to the stable ones."} {"geneset":"PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN","description":"Genes down-regulated in unstable ateroslerotic plaques compared to the stable ones."} {"geneset":"DITTMER_PTHLH_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DITTMER_PTHLH_TARGETS_UP","description":"Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of PTHLH [GeneID=5744] by RNAi."} {"geneset":"DITTMER_PTHLH_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DITTMER_PTHLH_TARGETS_DN","description":"Genes down-regulated in MDA-MB-231 cells (breast cancer) after knockdown of PTHLH [GeneID=5744] by RNAi."} {"geneset":"UDAYAKUMAR_MED1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/UDAYAKUMAR_MED1_TARGETS_UP","description":"Genes up-regulated in HeLa cells after knockdown of MED1 [GeneID=5469] by RNAi."} {"geneset":"UDAYAKUMAR_MED1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/UDAYAKUMAR_MED1_TARGETS_DN","description":"Genes down-regulated in HeLa cells after knockdown of MED1 [GeneID=5469] by RNAi."} {"geneset":"ODONNELL_TFRC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ODONNELL_TFRC_TARGETS_UP","description":"Genes up-regulated in P493-6 cells (B lymphocyte, Burkitt's lymphoma model) upon knockdown of TFRC [GeneID=7037] by RNAi."} {"geneset":"ODONNELL_TFRC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ODONNELL_TFRC_TARGETS_DN","description":"Genes down-regulated in P493-6 cells (B lymphocyte, Burkitt's lymphoma model) upon knockdown of TFRC [GeneID=7037] by RNAi."} {"geneset":"ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP","description":"Genes down-regulated in P493-6 cells (B lymphocyte, Burkitt's lymphoma model) by MYC [GeneID=4609] and up-regulated by RNAi knockdown of TFRC [GeneID=7037]."} {"geneset":"ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN","description":"Genes up-regulated in P493-6 cells (B lymphocyte, Burkitt's lymphoma model) by MYC [GeneID=4609] and down-regulated by RNAi knockdown of TFRC [GeneID=7037]."} {"geneset":"SENESE_HDAC1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENESE_HDAC1_TARGETS_UP","description":"Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [GeneID=3065] by RNAi."} {"geneset":"SENESE_HDAC1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENESE_HDAC1_TARGETS_DN","description":"Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [GeneID=3065] by RNAi."} {"geneset":"SENESE_HDAC1_AND_HDAC2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENESE_HDAC1_AND_HDAC2_TARGETS_UP","description":"Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of both HDAC1 and HDAC2 [GeneID=3065;3066] by RNAi."} {"geneset":"SENESE_HDAC1_AND_HDAC2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENESE_HDAC1_AND_HDAC2_TARGETS_DN","description":"Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of both HDAC1 and HDAC2 [GeneID=3065;3066] by RNAi."} {"geneset":"SENESE_HDAC2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENESE_HDAC2_TARGETS_UP","description":"Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC2 [GeneID=3066] by RNAi."} {"geneset":"SENESE_HDAC2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENESE_HDAC2_TARGETS_DN","description":"Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC2 [GeneID=3066] by RNAi."} {"geneset":"SENESE_HDAC3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENESE_HDAC3_TARGETS_UP","description":"Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [GeneID=8841] by RNAi."} {"geneset":"SENESE_HDAC3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENESE_HDAC3_TARGETS_DN","description":"Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [GeneID=8841] by RNAi."} {"geneset":"LEE_NEURAL_CREST_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_NEURAL_CREST_STEM_CELL_UP","description":"Genes up-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]."} {"geneset":"LEE_NEURAL_CREST_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_NEURAL_CREST_STEM_CELL_DN","description":"Genes down-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]."} {"geneset":"HUMMEL_BURKITTS_LYMPHOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUMMEL_BURKITTS_LYMPHOMA_UP","description":"Up-regulated genes constituting the molecular signature of Burkitt 's lymphoma."} {"geneset":"HUMMEL_BURKITTS_LYMPHOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUMMEL_BURKITTS_LYMPHOMA_DN","description":"Down-regulated genes constituting the molecular signature of Burkitt 's lymphoma."} {"geneset":"TIEN_INTESTINE_PROBIOTICS_2HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIEN_INTESTINE_PROBIOTICS_2HR_UP","description":"Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 2h."} {"geneset":"TIEN_INTESTINE_PROBIOTICS_2HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIEN_INTESTINE_PROBIOTICS_2HR_DN","description":"Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 2h."} {"geneset":"TIEN_INTESTINE_PROBIOTICS_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIEN_INTESTINE_PROBIOTICS_6HR_UP","description":"Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 6h."} {"geneset":"TIEN_INTESTINE_PROBIOTICS_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIEN_INTESTINE_PROBIOTICS_6HR_DN","description":"Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 6h."} {"geneset":"TIEN_INTESTINE_PROBIOTICS_24HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIEN_INTESTINE_PROBIOTICS_24HR_UP","description":"Genes up-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h."} {"geneset":"TIEN_INTESTINE_PROBIOTICS_24HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIEN_INTESTINE_PROBIOTICS_24HR_DN","description":"Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 24h."} {"geneset":"ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP","description":"Genes up-regulated in macrophages by P.gingivalis FimA pathogen."} {"geneset":"ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN","description":"Genes down-regulated in macrophages by P.gingivalis FimA pathogen."} {"geneset":"ZHOU_INFLAMMATORY_RESPONSE_LPS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_INFLAMMATORY_RESPONSE_LPS_UP","description":"Genes up-regulated in macrophages by P.gingivalis LPS (lipopolysaccharide)."} {"geneset":"KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP","description":"Genes up-regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1-FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein."} {"geneset":"KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN","description":"Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1-FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein."} {"geneset":"SABATES_COLORECTAL_ADENOMA_SIZE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SABATES_COLORECTAL_ADENOMA_SIZE_UP","description":"A selection of genes whose expression displayed significant positive correlation with size of colorectal adenoma."} {"geneset":"SABATES_COLORECTAL_ADENOMA_SIZE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SABATES_COLORECTAL_ADENOMA_SIZE_DN","description":"A selection of genes whose expression displayed significant negative correlation with size of colorectal adenoma."} {"geneset":"SABATES_COLORECTAL_ADENOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SABATES_COLORECTAL_ADENOMA_UP","description":"Genes up-regulated in colorectal adenoma compared to normal mucosa samples."} {"geneset":"SABATES_COLORECTAL_ADENOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SABATES_COLORECTAL_ADENOMA_DN","description":"Genes down-regulated in colorectal adenoma compared to normal mucosa samples."} {"geneset":"SCIBETTA_KDM5B_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCIBETTA_KDM5B_TARGETS_UP","description":"Genes up-regulated in HB2 cells (mammary epithelium) upon expression of KDM5B [GeneID=10765] off an adenoviral vector."} {"geneset":"SCIBETTA_KDM5B_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCIBETTA_KDM5B_TARGETS_DN","description":"Genes down-regulated in HB2 cells (mammary epithelium) upon expression of KDM5B [GeneID=10765] off an adenoviral vector."} {"geneset":"NAGASHIMA_NRG1_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAGASHIMA_NRG1_SIGNALING_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) after stimulation with NRG1 [GeneID=3084]."} {"geneset":"NAGASHIMA_NRG1_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAGASHIMA_NRG1_SIGNALING_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) after stimulation with NRG1 [GeneID=3084]."} {"geneset":"NAGASHIMA_EGF_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAGASHIMA_EGF_SIGNALING_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) after stimulation with EGF [GeneID=1950]."} {"geneset":"KIM_WT1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_WT1_TARGETS_UP","description":"Genes up-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [GeneID=7490]."} {"geneset":"KIM_WT1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_WT1_TARGETS_DN","description":"Genes down-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [GeneID=7490]."} {"geneset":"KIM_WT1_TARGETS_8HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_WT1_TARGETS_8HR_UP","description":"Genes up-regulated in UB27 cells (osteosarcoma) at 8 hr after inducing the expression of a mutant form of WT1 [GeneID=7490]."} {"geneset":"KIM_WT1_TARGETS_8HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_WT1_TARGETS_8HR_DN","description":"Genes down-regulated in UB27 cells (osteosarcoma) at 8 hr after inducing the expression of a mutant form of WT1 [GeneID=7490]."} {"geneset":"KIM_WT1_TARGETS_12HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_WT1_TARGETS_12HR_UP","description":"Genes up-regulated in UB27 cells (osteosarcoma) at 12 hr after inducing the expression of a mutated form of WT1 [GeneID=7490]."} {"geneset":"KIM_WT1_TARGETS_12HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_WT1_TARGETS_12HR_DN","description":"Genes down-regulated in UB27 cells (osteosarcoma) at 12 hr after inducing the expression of a mutated form of WT1 [GeneID=7490]."} {"geneset":"ELVIDGE_HYPOXIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HYPOXIA_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) under hypoxia conditions."} {"geneset":"ELVIDGE_HYPOXIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HYPOXIA_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) under hypoxia conditions."} {"geneset":"ELVIDGE_HYPOXIA_BY_DMOG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HYPOXIA_BY_DMOG_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) treated with hypoxia mimetic DMOG [PubChem=3080614]."} {"geneset":"ELVIDGE_HYPOXIA_BY_DMOG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HYPOXIA_BY_DMOG_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) treated with hypoxia mimetic DMOG [PubChem=3080614]."} {"geneset":"ELVIDGE_HIF1A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HIF1A_TARGETS_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [GeneID=3091] by RNAi."} {"geneset":"ELVIDGE_HIF1A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HIF1A_TARGETS_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [GeneID=3091] by RNAi."} {"geneset":"ELVIDGE_HIF2A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HIF2A_TARGETS_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) after knockdown of HIF2A [GeneID=2034] by RNAi."} {"geneset":"ELVIDGE_HIF1A_AND_HIF2A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HIF1A_AND_HIF2A_TARGETS_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) after knockdown of both HIF1A and HIF2A [GeneID=3091;2034] by RNAi."} {"geneset":"ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) after knockdown of both HIF1A and HIF2A [GeneID=3091;2034] by RNAi."} {"geneset":"JAATINEN_HEMATOPOIETIC_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAATINEN_HEMATOPOIETIC_STEM_CELL_UP","description":"Genes up-regulated in CD133+ [GeneID=8842] cells (hematopoietic stem cells, HSC) compared to the CD133- cells."} {"geneset":"JAATINEN_HEMATOPOIETIC_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAATINEN_HEMATOPOIETIC_STEM_CELL_DN","description":"Genes down-regulated in CD133+ [GeneID=8842] cells (hematopoietic stem cells, HSC) compared to the CD133- cells."} {"geneset":"MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_UP","description":"Genes up-regulated in FSHD (facioscapulohumeral muscular dystrophy) mesoangioblasts."} {"geneset":"MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_DN","description":"Genes down-regulated in FSHD (facioscapulohumeral muscular dystrophy) mesoangioblasts."} {"geneset":"GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP","description":"Genes up-regulated in quiescent (G0) vs dividing (M) CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients."} {"geneset":"GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_DN","description":"Genes down-regulated in quiescent (G0) vs dividing (M) CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients."} {"geneset":"GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP","description":"Genes up-regulated in quiescent (G0) CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients compared to the quiescent cells from normal donors."} {"geneset":"GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN","description":"Genes down-regulated in quiescent (G0) CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients compared to the quiescent cells from normal donors."} {"geneset":"GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP","description":"Genes up-regulated in quescent CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloblastic leukemia) patients compared to the dividing cells from normal donors."} {"geneset":"GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_DN","description":"Genes down-regulated in quescent CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloblastic leukemia) patients compared to the dividing cells from normal donors."} {"geneset":"GRAHAM_CML_DIVIDING_VS_NORMAL_DIVIDING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_DIVIDING_VS_NORMAL_DIVIDING_UP","description":"Genes up-regulated in dividing CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients compared to the dividing cells from normal donors."} {"geneset":"GRAHAM_CML_DIVIDING_VS_NORMAL_DIVIDING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_DIVIDING_VS_NORMAL_DIVIDING_DN","description":"Genes down-regulated in dividing CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients compared to the dividing cells from normal donors."} {"geneset":"GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP","description":"Genes up-regulated in quiescent CD34+ [GeneID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients."} {"geneset":"GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN","description":"Genes down-regulated in quiescent CD34+ [GeneID=8842] cells isolated from peripheral blood of normal donors compared to the dividing cells from CML (chronic myeloid leukemia) patients."} {"geneset":"GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP","description":"Genes up-regulated in quiescent vs dividing CD34+ [GeneID=8842] cells isolated from peripheral blood of normal donors."} {"geneset":"GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN","description":"Genes down-regulated in quiescent vs dividing CD34+ [GeneID=8842] cells isolated from peripheral blood of normal donors."} {"geneset":"BIDUS_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIDUS_METASTASIS_UP","description":"Genes up-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases."} {"geneset":"BIDUS_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIDUS_METASTASIS_DN","description":"Genes down-regulated in endometroid endometrial tumors from patients with lymph node metastases compared to those without the metastases."} {"geneset":"WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP","description":"Genes up-regulated in mucinous ovarian carcinoma tumors of low malignant potential (LMP) compared to normal ovarian surface epithelium tissue."} {"geneset":"WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN","description":"Genes down-regulated in mucinous ovarian carcinoma tumors of low malignant potential (LMP) compared to normal ovarian surface epithelium tissue."} {"geneset":"WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP","description":"Genes up-regulated in mucinous ovarian carcinoma tumors of grades 1 and 2 compared to the normal ovarian survace epithelium tissue."} {"geneset":"WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN","description":"Genes down-regulated in mucinous ovarian carcinoma tumors of grades 1 and 2 compared to the normal ovarian survace epithelium tissue."} {"geneset":"MAYBURD_RESPONSE_TO_L663536_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAYBURD_RESPONSE_TO_L663536_UP","description":"Genes up-regulated in H720 cells (lung cancer) after treatment with L663536 (MK886) [PubChem=105049], an inhibitor of leukotriene biosynthesis."} {"geneset":"MAYBURD_RESPONSE_TO_L663536_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAYBURD_RESPONSE_TO_L663536_DN","description":"Genes down-regulated in H720 cells (lung cancer) after treatment with L663536 (MK886) [PubChem=105049], an inhibitor of leukotriene biosynthesis."} {"geneset":"WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP","description":"Genes up-regulated in non-neoplastic rectal mucosa samples from patients having cancer associated with ulcerative collitis, compared to those who did not have the cancer."} {"geneset":"WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_DN","description":"Genes down-regulated in non-neoplastic rectal mucosa samples from patients having cancer associated with ulcerative collitis, compared to those who did not have the cancer."} {"geneset":"DODD_NASOPHARYNGEAL_CARCINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DODD_NASOPHARYNGEAL_CARCINOMA_UP","description":"Genes up-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue."} {"geneset":"DODD_NASOPHARYNGEAL_CARCINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DODD_NASOPHARYNGEAL_CARCINOMA_DN","description":"Genes down-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue."} {"geneset":"RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP","description":"Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue."} {"geneset":"RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN","description":"Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue."} {"geneset":"RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP","description":"Genes up-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue."} {"geneset":"RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN","description":"Genes down-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue."} {"geneset":"RODRIGUES_THYROID_CARCINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_THYROID_CARCINOMA_UP","description":"Genes up-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to anaplastic thyroid carcinoma (ATC)."} {"geneset":"RODRIGUES_THYROID_CARCINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_THYROID_CARCINOMA_DN","description":"Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to anaplastic thyroid carcinoma (ATC)."} {"geneset":"GOZGIT_ESR1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOZGIT_ESR1_TARGETS_UP","description":"Genes up-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [GeneID=2099]) compared to the parental MCF7 cells which do."} {"geneset":"GOZGIT_ESR1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOZGIT_ESR1_TARGETS_DN","description":"Genes down-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [GeneID=2099]) compared to the parental MCF7 cells which do."} {"geneset":"HAHTOLA_SEZARY_SYNDROM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_SEZARY_SYNDROM_UP","description":"Genes up-regulated in monocytes isolated from peripheral blood samples of Sezary syndrom patients compared to those from healthy normal donors."} {"geneset":"HAHTOLA_SEZARY_SYNDROM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_SEZARY_SYNDROM_DN","description":"Genes down-regulated in monocytes isolated from peripheral blood samples of Sezary syndrom patients compared to those from healthy normal donors."} {"geneset":"HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP","description":"Genes up-regulated in lesional skin biopsies from mycosis fundoides patients compared to the normal skin samples."} {"geneset":"HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_DN","description":"Genes down-regulated in lesional skin biopsies from mycosis fundoides patients compared to the normal skin samples."} {"geneset":"HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP","description":"Genes up-regulated in T helper cells (defines as CD4+) isolated from patients with mucosis fungoides compared to those from normal control donors."} {"geneset":"HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN","description":"Genes down-regulated in T helper cells (defines as CD4+) isolated from patients with mucosis fungoides compared to those from normal control donors."} {"geneset":"HAHTOLA_MYCOSIS_FUNGOIDES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_MYCOSIS_FUNGOIDES_UP","description":"Genes up-regulated in monocytes isolated from peripheral blood samples of patients with mucosis fungoides compared to those from normal healthy donors."} {"geneset":"HAHTOLA_MYCOSIS_FUNGOIDES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_MYCOSIS_FUNGOIDES_DN","description":"Genes down-regulated in monocytes isolated from peripheral blood samples of patients with mucosis fungoides compared to those from normal healthy donors."} {"geneset":"PROVENZANI_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PROVENZANI_METASTASIS_UP","description":"Genes up-regulated in polysomal and total RNA samples from SW480 cells (primary colorectal carcinoma, CRC) compared to the SW620 cells (lymph node metastasis from the same individual)."} {"geneset":"PROVENZANI_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PROVENZANI_METASTASIS_DN","description":"Genes down-regulated in polysomal and total RNA samples from SW480 cells (primary colorectal carcinoma, CRC) compared to the SW620 cells (lymph node metastasis from the same individual)."} {"geneset":"PACHER_TARGETS_OF_IGF1_AND_IGF2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PACHER_TARGETS_OF_IGF1_AND_IGF2_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) by IGF1 and IGF2 [GeneID=3479;3481]."} {"geneset":"LIU_CDX2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_CDX2_TARGETS_UP","description":"Genes up-regulated in HET1A cells (esophagus epithelium) engineered to stably express CDX2 [GeneID=1045]."} {"geneset":"LIU_CDX2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_CDX2_TARGETS_DN","description":"Genes down-regulated in HET1A cells (esophagus epithelium) engineered to stably express CDX2 [GeneID=1045]."} {"geneset":"COLDREN_GEFITINIB_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLDREN_GEFITINIB_RESISTANCE_UP","description":"Genes up-regulated in NSCLC (non-small cell lung carcinoma) cell lines resistant to gefitinib [PubChem=123631] compared to the sensitive ones."} {"geneset":"COLDREN_GEFITINIB_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLDREN_GEFITINIB_RESISTANCE_DN","description":"Genes down-regulated in NSCLC (non-small cell lung carcinoma) cell lines resistant to gefitinib [PubChem=123631] compared to the sensitive ones."} {"geneset":"KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP","description":"Genes up-regulated in MEWO cells (melanoma) after 48h of methionine [PubChem=876] deprivation."} {"geneset":"KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_DN","description":"Genes down-regulated in MEWO cells (melanoma) after 48h of methionine [PubChem=876] deprivation."} {"geneset":"KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP","description":"Genes up-regulated in MEWO cells (melanoma) after 96 h of methionine [PubChem=876] deprivation."} {"geneset":"KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN","description":"Genes down-regulated in MEWO cells (melanoma) after 96 h of methionine [PubChem=876] deprivation."} {"geneset":"PASTURAL_RIZ1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PASTURAL_RIZ1_TARGETS_UP","description":"Genes up-regulated in K562 (chronic myelogenous leukemia, CML) cells engineered to stably express RIZ1 [GeneID=7799]."} {"geneset":"PASTURAL_RIZ1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PASTURAL_RIZ1_TARGETS_DN","description":"Genes down-regulated in K562 (chronic myelogenous leukemia, CML) cells engineered to stably express RIZ1 [GeneID=7799]."} {"geneset":"CHOW_RASSF1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHOW_RASSF1_TARGETS_UP","description":"Genes up-regulated in C666-1 cells (nasopharyngeal carcinoma) by stable expression of RASSF1 [GeneID=11186]."} {"geneset":"CHOW_RASSF1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHOW_RASSF1_TARGETS_DN","description":"Genes down-regulated in C666-1 cells (nasopharyngeal carcinoma) by stable expression of RASSF1 [GeneID=11186]."} {"geneset":"ENK_UV_RESPONSE_EPIDERMIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ENK_UV_RESPONSE_EPIDERMIS_UP","description":"Genes up-regulated in epidermis after to UVB irradiation."} {"geneset":"ENK_UV_RESPONSE_EPIDERMIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ENK_UV_RESPONSE_EPIDERMIS_DN","description":"Genes down-regulated in epidermis after to UVB irradiation."} {"geneset":"ENK_UV_RESPONSE_KERATINOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ENK_UV_RESPONSE_KERATINOCYTE_UP","description":"Genes up-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation."} {"geneset":"ENK_UV_RESPONSE_KERATINOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ENK_UV_RESPONSE_KERATINOCYTE_DN","description":"Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation."} {"geneset":"LANDIS_BREAST_CANCER_PROGRESSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDIS_BREAST_CANCER_PROGRESSION_UP","description":"Genes up-regulated in preneoplastic mammary tissues and whose expression is maintained in tumors."} {"geneset":"LANDIS_BREAST_CANCER_PROGRESSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDIS_BREAST_CANCER_PROGRESSION_DN","description":"Genes down-regulated in preneoplastic mammary tissues and whose expression is maintained in tumors."} {"geneset":"GESERICK_TERT_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GESERICK_TERT_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblasts) with TERT [GeneID=7015] knockout, after expression of the gene off a retroviral vector."} {"geneset":"YEMELYANOV_GR_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YEMELYANOV_GR_TARGETS_DN","description":"Transcription factors down-regulated in LNCaP cells (prostate cancer) by expression of GR [GeneID=2908] off a lentiviral vector."} {"geneset":"LAU_APOPTOSIS_CDKN2A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LAU_APOPTOSIS_CDKN2A_UP","description":"Genes up-regulated by UV-irradiation in cervical cancer cells after knockdown of CDKN2A [GeneID=1029]."} {"geneset":"LAU_APOPTOSIS_CDKN2A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LAU_APOPTOSIS_CDKN2A_DN","description":"Genes down-regulated by UV-irradiation in cervical cancer cells after knockdown of CDKN2A [GeneID=1029]."} {"geneset":"DELYS_THYROID_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELYS_THYROID_CANCER_UP","description":"Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue."} {"geneset":"DELYS_THYROID_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELYS_THYROID_CANCER_DN","description":"Genes down-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue."} {"geneset":"CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP","description":"Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by activated KRAS [GeneID=3845] vs those reverted to normal cells upon over-expression of a dominant negative form of CDC25 [GeneID=5923]."} {"geneset":"CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN","description":"Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by activated KRAS [GeneID=3845] vs those reverted to normal cells upon over-expression of a dominant negative form of CDC25 [GeneID=5923]."} {"geneset":"CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP","description":"Genes up-regulated in transformed NIH3T3 cells (fibroblasts transformed by activated KRAS [GeneID=3845]) vs normal cells."} {"geneset":"CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN","description":"Genes down-regulated in transformed NIH3T3 cells (fibroblasts transformed by activated KRAS [GeneID=3845]) vs normal cells."} {"geneset":"CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP","description":"Genes up-regulated in reverted NIH3T3 cells (fibroblasts transformed by activated KRAS [GeneID=3845] which then reverted to normal cells upon stable over-expression of a dominant negative form of CDC25 [GeneID=5923]) vs normal fibroblasts."} {"geneset":"CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN","description":"Genes down-regulated in reverted NIH3T3 cells (fibroblasts transformed by activated KRAS [GeneID=3845] which then reverted to normal cells upon stable over-expression of a dominant negative form of CDC25 [GeneID=5923]) vs normal fibroblasts."} {"geneset":"CASTELLANO_HRAS_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASTELLANO_HRAS_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) isolated from HRAS [GeneID=3265] knockout mice."} {"geneset":"CASTELLANO_HRAS_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASTELLANO_HRAS_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) isolated from HRAS [GeneID=3265] knockout mice."} {"geneset":"CASTELLANO_HRAS_AND_NRAS_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASTELLANO_HRAS_AND_NRAS_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblasts) isolated from HRAS and NRAS [GeneID=3265;4893] double knockout mice."} {"geneset":"CASTELLANO_HRAS_AND_NRAS_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASTELLANO_HRAS_AND_NRAS_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblasts) isolated from HRAS and NRAS [GeneID=3265;4893] double knockout mice."} {"geneset":"CASTELLANO_NRAS_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASTELLANO_NRAS_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) isolated from NRAS [GeneID=4893] knockout mice."} {"geneset":"CASTELLANO_NRAS_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CASTELLANO_NRAS_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) isolated from NRAS [GeneID=4893] knockout mice."} {"geneset":"CHEBOTAEV_GR_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEBOTAEV_GR_TARGETS_UP","description":"Genes up-regulated in follicular epithelial stem cells after transgenic expression of GR [GeneID=2908] under control of the keratin5 (K5) [GeneID=3852] promoter."} {"geneset":"CHEBOTAEV_GR_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEBOTAEV_GR_TARGETS_DN","description":"Genes down-regulated in follicular epithelial stem cells after transgenic expression of GR [GeneID=2908] under control of the keratin5 (K5) [GeneID=3852] promoter."} {"geneset":"BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_UP","description":"Genes up-regulated in NIH3T3 cells (fibroblasts) after treatment with Y27632 [PubChem=123862], an inhibitor of ROCK proteins; the changes did not depend on expression of constitutively active (Q63L) form of RHOA [GeneID=387]."} {"geneset":"BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN","description":"Genes down-regulated in NIH3T3 cells (fibroblasts) after treatment with Y27632 [PubChem=123862], an inhibitor of ROCK proteins; the changes did not depend on expression of constitutively active (Q63L) form of RHOA [GeneID=387]."} {"geneset":"BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_UP","description":"Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector; their expression reverted completely after treatment with Y27632 [PubChem=123862], an inhibitor of ROCK proteins."} {"geneset":"BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN","description":"Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector; their expression reverted completely after treatment with Y27632 [PubChem=123862], an inhibitor of ROCK proteins."} {"geneset":"LINDGREN_BLADDER_CANCER_CLUSTER_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_CLUSTER_1_UP","description":"Up-regulated genes whose expression profile is specific to Custer I of urothelial cell carcinoma (UCC) tumors."} {"geneset":"LINDGREN_BLADDER_CANCER_CLUSTER_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_CLUSTER_1_DN","description":"Down-regulated genes whose expression profile is specific to Custer I of urothelial cell carcinoma (UCC) tumors."} {"geneset":"LINDGREN_BLADDER_CANCER_CLUSTER_2A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_CLUSTER_2A_UP","description":"Genes whose expression profile is specific to Cluster IIa of urothelial cell carcinoma (UCC) tumors."} {"geneset":"LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN","description":"Genes whose expression profile is specific to Cluster IIa of urothelial cell carcinoma (UCC) tumors."} {"geneset":"LINDGREN_BLADDER_CANCER_CLUSTER_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_CLUSTER_3_UP","description":"Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors."} {"geneset":"LINDGREN_BLADDER_CANCER_CLUSTER_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_CLUSTER_3_DN","description":"Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors."} {"geneset":"KOINUMA_COLON_CANCER_MSI_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOINUMA_COLON_CANCER_MSI_UP","description":"Genes up-regulated in colorectal carcinoma samples positive for MSI (microsatellite instability) compared to the MSI negative ones."} {"geneset":"KOINUMA_COLON_CANCER_MSI_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOINUMA_COLON_CANCER_MSI_DN","description":"Genes down-regulated in colorectal carcinoma samples positive for MSI (microsatellite instability) compared to the MSI negative ones."} {"geneset":"CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP","description":"Genes in the AKT1 [GeneID=207] pathway which are independent of MTOR [GeneID=2475], insensitive to RAD001 (everolimus) [PubChem=6442177]."} {"geneset":"CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN","description":"Genes in the AKT1 [GeneID=207] pathway which depend on MTOR [GeneID=2475], sensitive to RAD001 (everolimus) [PubChem=6442177]."} {"geneset":"NADERI_BREAST_CANCER_PROGNOSIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NADERI_BREAST_CANCER_PROGNOSIS_UP","description":"Up-regulated genes in the breast cancer prognostic signature of 70 genes that significantly correlated with survival."} {"geneset":"NADERI_BREAST_CANCER_PROGNOSIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NADERI_BREAST_CANCER_PROGNOSIS_DN","description":"Down-regulated genes in the breast cancer prognostic signature of 70 genes that significantly correlated with survival."} {"geneset":"MARKEY_RB1_CHRONIC_LOF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARKEY_RB1_CHRONIC_LOF_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblasts) isolated from RB1 [GeneID=5925] knockout mice: chronic loss of function (LOF) of RB1."} {"geneset":"MARKEY_RB1_CHRONIC_LOF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARKEY_RB1_CHRONIC_LOF_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblasts) isolated from RB1 [GeneID=5925] knockout mice: chronic loss of function (LOF) of RB1."} {"geneset":"MARKEY_RB1_ACUTE_LOF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARKEY_RB1_ACUTE_LOF_UP","description":"Genes up-regulated in adult fibroblasts with inactivated RB1 [GeneID=5925] by Cre-lox: acute loss of function (LOF) of RB1."} {"geneset":"MARKEY_RB1_ACUTE_LOF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARKEY_RB1_ACUTE_LOF_DN","description":"Genes down-regulated in adult fibroblasts with inactivated RB1 [GeneID=5925] by Cre-lox: acute loss of function (LOF) of RB1."} {"geneset":"CHIN_BREAST_CANCER_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIN_BREAST_CANCER_COPY_NUMBER_UP","description":"Genes from common regions of gains observed in more than 15% of 148 primary breast cancer tumors."} {"geneset":"CHIN_BREAST_CANCER_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIN_BREAST_CANCER_COPY_NUMBER_DN","description":"Genes from common regions of losses observed in more than 15% of 148 primary breast cancer tumors."} {"geneset":"GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP","description":"Genes up-regulated in ME-A cells (breast cancer) undergoing apoptosis upon serum starvation (5% to 0% FCS) for 22 hr."} {"geneset":"GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN","description":"Genes down-regulated in ME-A cells (breast cancer) undergoing apoptosis upon serum starvation (5% to 0% FCS) for 22 hr."} {"geneset":"VANHARANTA_UTERINE_FIBROID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANHARANTA_UTERINE_FIBROID_UP","description":"Genes up-regulated in uterine fibroids vs normal myometrium samples."} {"geneset":"VANHARANTA_UTERINE_FIBROID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANHARANTA_UTERINE_FIBROID_DN","description":"Genes down-regulated in uterine fibroids vs normal myometrium samples."} {"geneset":"VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_UP","description":"Genes up-regulated in uterine fibroids with deletions in the 7q region vs those without the deletion."} {"geneset":"VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_DN","description":"Genes down-regulated in uterine fibroids with deletions in the 7q region vs those without the deletion."} {"geneset":"LANDIS_ERBB2_BREAST_TUMORS_65_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDIS_ERBB2_BREAST_TUMORS_65_UP","description":"Up-regulated genes from the 65 most significantly changed (p<0.01) genes identified by two analytical methods in the mammary tumors induced by transgenic expression of ERBB2 [GeneID=2064]."} {"geneset":"LANDIS_ERBB2_BREAST_TUMORS_65_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDIS_ERBB2_BREAST_TUMORS_65_DN","description":"Down-regulated genes from the 65 most significantly changed (p<0.01) genes identified by two analytical methods in the mammary tumors induced by transgenic expression of ERBB2 [GeneID=2064]."} {"geneset":"LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP","description":"Up-regulated genes from top 82 genes out of the 324-gene signature identified in the pre-neoplastic tissue adjacent to the mammary tumors induced by transgenic expression of ERBB2 [GeneID=2064]."} {"geneset":"LANDIS_ERBB2_BREAST_PRENEOPLASTIC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDIS_ERBB2_BREAST_PRENEOPLASTIC_DN","description":"Down-regulated genes from top 82 genes out of the 324-gene signature identified in the pre-neoplastic tissue adjacent to the mammary tumors induced by transgenic expression of ERBB2 [GeneID=2064]."} {"geneset":"CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP","description":"Genes up-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402], a protease inhibitor causing apoptosis."} {"geneset":"CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN","description":"Genes down-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402], a protease inhibitor causing apoptosis."} {"geneset":"ODONNELL_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ODONNELL_METASTASIS_UP","description":"Up-regulated genes in the signature set for lymph node metastasis in head and neck squamous cell carcinoma (HNSCC)."} {"geneset":"ODONNELL_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ODONNELL_METASTASIS_DN","description":"Down-regulated genes in the signature set for lymph node metastasis in head and neck squamous cell carcinoma (HNSCC)."} {"geneset":"GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP","description":"Genes up-regulated in ME-A cells (breast cancer, sensitive to apoptotic stimuli) upon serum deprivation for 22 hr in the presence of medium concentrate (MC) from ME-C cells (breast cancer, resistant to apoptotic stimuli)."} {"geneset":"GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN","description":"Genes down-regulated in ME-A cells (breast cancer, sensitive to apoptotic stimuli) upon serum deprivation for 22 hr in the presence of medium concentrate (MC) from ME-C cells (breast cancer, resistant to apoptotic stimuli)."} {"geneset":"GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP","description":"Genes up-regulated in ME-A cells (breast cancer) undergoing apoptosis in response to doxorubicin [PubChem=31703]."} {"geneset":"GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN","description":"Genes down-regulated in ME-A cells (breast cancer) undergoing apoptosis in response to doxorubicin [PubChem=31703]."} {"geneset":"GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP","description":"Genes up-regulated in ME-A cells (breast cancer, sensitive to apoptotic stimuli) exposed to doxorubicin [PubChem=31703] in the presence of medium concentrate (MC) from ME-C cells (breast cancer, resistant to apoptotic stimuli)."} {"geneset":"GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN","description":"Genes down-regulated in ME-A cells (breast cancer, sensitive to apoptotic stimuli) exposed to doxorubicin [PubChem=31703] in the presence of medium concentrate (MC) from ME-C cells (breast cancer, resistant to apoptotic stimuli)."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP","description":"Up-regulated genes from the set A (Fig. 5a): specific to cells expressing MLL-AF4 [GeneID=4297;4299] fusion protein alone."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN","description":"Down-regulated genes from the set A (Fig. 5a): specific to cells expressing MLL-AF4 [GeneID=4297;4299] fusion protein alone."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP","description":"Up-regulated genes from the set B (Fig. 5a): specific signature shared by cells expressing either AF4-MLL or MLL-AF4 [GeneID=4299;4297] fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_DN","description":"Down-regulated genes from the set B (Fig. 5a): specific signature shared by cells expressing either AF4-MLL or MLL-AF4 [GeneID=4299;4297] fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP","description":"Up-regulated genes from the set C (Fig. 5a): specific to cells expressing AF4-MLL [GeneID=4299;4297] fusion protein alone."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN","description":"Down-regulated genes from the set C (Fig. 5a): specific to cells expressing AF4-MLL [GeneID=4299;4297] fusion protein alone."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP","description":"Up-regulated genes from the set D (Fig. 5a): specific signature shared by cells expressing MLL-AF4 [GeneID=4297;4299] alone and those expressing both MLL-AF4 and AF4-MLL fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_DN","description":"Down-regulated genes from the set D (Fig. 5a): specific signature shared by cells expressing MLL-AF4 [GeneID=4297;4299] alone and those expressing both MLL-AF4 and AF4-MLL fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP","description":"Up-regulated genes from the set E (Fig. 5a): specific signature shared by cells expressing either MLL-AF4 [GeneID=4297;4299] or AF4-MLL fusion proteins alone, and those expressing both fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_DN","description":"Down-regulated genes from the set E (Fig. 5a): specific signature shared by cells expressing either MLL-AF4 [GeneID=4297;4299] or AF4-MLL fusion proteins alone, and those expressing both fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP","description":"Up-regualted genes from the set F (Fig. 5a): specific signature shared by cells expressing AF4-MLL [GeneID=4299;4297] alone and those expressing both AF4-MLL and MLL-AF4 fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN","description":"Down-regualted genes from the set F (Fig. 5a): specific signature shared by cells expressing AF4-MLL [GeneID=4299;4297] alone and those expressing both AF4-MLL and MLL-AF4 fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP","description":"Up-regulated genes from the set G (Fig. 5a): specific to cells expressing both MLL-AF4 [GeneID=4297;4299] and AF4-MLL fusion proteins."} {"geneset":"GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_DN","description":"Down-regulated genes from the set G (Fig. 5a): specific to cells expressing both MLL-AF4 [GeneID=4297;4299] and AF4-MLL fusion proteins."} {"geneset":"BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_UP","description":"Genes up-regulated in NIH3T3 cells (fibroblasts) transfrormed by expression of constitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector; their expression did NOT reverted completely after treatment with Y27632 [PubChem=123862], an inhibitor of ROCK proteins."} {"geneset":"BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN","description":"Genes down-regulated in NIH3T3 cells (fibroblasts) transfrormed by expression of constitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector; their expression did NOT reverted completely after treatment with Y27632 [PubChem=123862], an inhibitor of ROCK proteins."} {"geneset":"CAIRO_PML_TARGETS_BOUND_BY_MYC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_PML_TARGETS_BOUND_BY_MYC_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblasts) after knockout of PML [GeneID=5371] and whose promoters were bound by MYC [GeneID=4609]."} {"geneset":"CAIRO_PML_TARGETS_BOUND_BY_MYC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_PML_TARGETS_BOUND_BY_MYC_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblasts) after knockout of PML [GeneID=5371] and whose promoters were bound by MYC [GeneID=4609]."} {"geneset":"OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP","description":"Genes up-regulated in epithelial ovarian cancer (EOC) biopsies: invasive (TOV) vs low malignant potential (LMP) tumors."} {"geneset":"OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_DN","description":"Genes down-regulated in epithelial ovarian cancer (EOC) biopsies: invasive (TOV) vs low malignant potential (LMP) tumors."} {"geneset":"LANDIS_ERBB2_BREAST_TUMORS_324_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDIS_ERBB2_BREAST_TUMORS_324_UP","description":"Up-regulated genes from the 324 genes identified by two analytical methods as changed in the mammary tumors induced by transgenic expression of ERBB2 [GeneID=2064]."} {"geneset":"LANDIS_ERBB2_BREAST_TUMORS_324_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDIS_ERBB2_BREAST_TUMORS_324_DN","description":"Down-regulated genes from the 324 genes identified by two analytical methods as changed in the mammary tumors induced by transgenic expression of ERBB2 [GeneID=2064]."} {"geneset":"BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_UP","description":"Up-regulated genes in non-neoplastic mucosa samples from colon cancer patients who developed recurrence of the disease."} {"geneset":"BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_DN","description":"Down-regulated genes in non-neoplastic mucosa samples from colon cancer patients who developed recurrence of the disease."} {"geneset":"BARRIER_CANCER_RELAPSE_TUMOR_SAMPLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BARRIER_CANCER_RELAPSE_TUMOR_SAMPLE_UP","description":"Up-regulated genes in tumor samples from colon cancer patients who developed recurrence of the disease."} {"geneset":"BARRIER_CANCER_RELAPSE_TUMOR_SAMPLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BARRIER_CANCER_RELAPSE_TUMOR_SAMPLE_DN","description":"Down-regulated genes in tumor samples from colon cancer patients who developed recurrence of the disease."} {"geneset":"BARIS_THYROID_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BARIS_THYROID_CANCER_UP","description":"Genes up-regulated in oncocytic follicular carcinoma (FTC) vs mitochondrial-rich papillary carcinoma (PTC) types of thyroid cancer."} {"geneset":"BARIS_THYROID_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BARIS_THYROID_CANCER_DN","description":"Genes down-regulated in oncocytic follicular carcinoma (FTC) vs mitochondrial-rich papillary carcinoma (PTC) types of thyroid cancer."} {"geneset":"BERENJENO_TRANSFORMED_BY_RHOA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERENJENO_TRANSFORMED_BY_RHOA_UP","description":"Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector."} {"geneset":"BERENJENO_TRANSFORMED_BY_RHOA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERENJENO_TRANSFORMED_BY_RHOA_DN","description":"Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector."} {"geneset":"TAKADA_GASTRIC_CANCER_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKADA_GASTRIC_CANCER_COPY_NUMBER_UP","description":"Candidate genes in the regions of copy number gain in gastric cancer cell lines."} {"geneset":"TAKADA_GASTRIC_CANCER_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKADA_GASTRIC_CANCER_COPY_NUMBER_DN","description":"Candidate genes in the regions of copy number loss in gastric cancer cell lines."} {"geneset":"WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_UP","description":"Genes up-regulated in esophageal adenocarcinoma (EAC) and Barret's esophagus (BE) relative to normal esophagi."} {"geneset":"WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN","description":"Genes down-regulated in esophageal adenocarcinoma (EAC) and Barret's esophagus (BE) relative to normal esophagi."} {"geneset":"KERLEY_RESPONSE_TO_CISPLATIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KERLEY_RESPONSE_TO_CISPLATIN_UP","description":"Genes genes up-regulated in NT2/D1 cells (embryonal carcinoma) in response to treatment with cisplatin [PubChem=2767]."} {"geneset":"KERLEY_RESPONSE_TO_CISPLATIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KERLEY_RESPONSE_TO_CISPLATIN_DN","description":"Genes genes down-regulated in NT2/D1 cells (embryonal carcinoma) in response to treatment with cisplatin [PubChem=2767]."} {"geneset":"MISSIAGLIA_REGULATED_BY_METHYLATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MISSIAGLIA_REGULATED_BY_METHYLATION_UP","description":"Genes up-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668], a DNA hypomethylating agent similar to azacitidine [PubChem=9444]."} {"geneset":"MISSIAGLIA_REGULATED_BY_METHYLATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MISSIAGLIA_REGULATED_BY_METHYLATION_DN","description":"Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668], a DNA hypomethylating agent similar to azacitidine [PubChem=9444]."} {"geneset":"TANG_SENESCENCE_TP53_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TANG_SENESCENCE_TP53_TARGETS_UP","description":"Genes up-regulated in WI-38 cells (senescent primary fibroblasts) after inactivation of TP53 [GeneID=7157] by GSE56 polypeptide."} {"geneset":"TANG_SENESCENCE_TP53_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TANG_SENESCENCE_TP53_TARGETS_DN","description":"Genes down-regulated in WI-38 cells (senescent primary fibroblasts) after inactivation of TP53 [GeneID=7157] by GSE56 polypeptide."} {"geneset":"WANG_BARRETTS_ESOPHAGUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_BARRETTS_ESOPHAGUS_UP","description":"Genes up-regulated in Barrett's esophagus compared to the normal tissue."} {"geneset":"WANG_BARRETTS_ESOPHAGUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_BARRETTS_ESOPHAGUS_DN","description":"Genes down-regulated in Barrett's esophagus compared to the normal tissue."} {"geneset":"WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP","description":"Up-regulated genes specific to esophageal adenocarcinoma (EAC) relative to normal tissue."} {"geneset":"WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN","description":"Down-regulated genes specific to esophageal adenocarcinoma (EAC) relative to normal tissue."} {"geneset":"WANG_ESOPHAGUS_CANCER_PROGRESSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_ESOPHAGUS_CANCER_PROGRESSION_UP","description":"Candidate progression biomarkers up-regulated in transition from non-tumor-risk associated to tumor-risk associated Barrett's esophagus and then to esophageal adenocarcinoma (EAC)."} {"geneset":"SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_UP","description":"Genes bound by EWSR1-FLT1 [GeneID=2130;2321] fusion and up-regulated in STA-ET-7.2 cells (Ewing's sarcoma) after knockdown of EWSR1-FLT1 by RNAi."} {"geneset":"SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_DN","description":"Genes bound by EWSR1-FLT1 [GeneID=2130;2321] fusion and down-regulated in STA-ET-7.2 cells (Ewing's sarcoma) after knockdown of EWSR1-FLT1 by RNAi."} {"geneset":"ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_UP","description":"Genes in discrete regions of gain within 16q region detected in individual invasive breast cancer tumors."} {"geneset":"ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_DN","description":"Genes in discrete regions of loss within 16q region detected in individual invasive breast cancer tumors."} {"geneset":"JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP","description":"Genes up-regulated in brain tumors induced by retroviral delivery of PDGFB [GeneID=5155]."} {"geneset":"JOHANSSON_GLIOMAGENESIS_BY_PDGFB_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHANSSON_GLIOMAGENESIS_BY_PDGFB_DN","description":"Genes down-regulated in brain tumors induced by retroviral delivery of PDGFB [GeneID=5155]."} {"geneset":"MCBRYAN_PUBERTAL_BREAST_3_4WK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_BREAST_3_4WK_UP","description":"Genes up-regulated during pubertal mammary gland development between weeks 3 and 4."} {"geneset":"MCBRYAN_PUBERTAL_BREAST_3_4WK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_BREAST_3_4WK_DN","description":"Genes down-regulated during pubertal mammary gland development between weeks 3 and 4."} {"geneset":"MCBRYAN_PUBERTAL_BREAST_4_5WK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_BREAST_4_5WK_UP","description":"Genes up-regulated during pubertal mammary gland development between week 4 and 5."} {"geneset":"MCBRYAN_PUBERTAL_BREAST_4_5WK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_BREAST_4_5WK_DN","description":"Genes down-regulated during pubertal mammary gland development between week 4 and 5."} {"geneset":"MCBRYAN_PUBERTAL_BREAST_5_6WK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_BREAST_5_6WK_UP","description":"Genes up-regulated during pubertal mammary gland development between week 5 and 6."} {"geneset":"MCBRYAN_PUBERTAL_BREAST_5_6WK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_BREAST_5_6WK_DN","description":"Genes down-regulated during pubertal mammary gland development between week 5 and 6."} {"geneset":"MCBRYAN_PUBERTAL_BREAST_6_7WK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_BREAST_6_7WK_UP","description":"Genes up-regulated during pubertal mammary gland development between week 6 and 7."} {"geneset":"MCBRYAN_PUBERTAL_BREAST_6_7WK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_BREAST_6_7WK_DN","description":"Genes down-regulated during pubertal mammary gland development between week 6 and 7."} {"geneset":"VETTER_TARGETS_OF_PRKCA_AND_ETS1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VETTER_TARGETS_OF_PRKCA_AND_ETS1_UP","description":"Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of PRKCA and ETS1 [GeneID=5578;2113] by RNAi."} {"geneset":"VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN","description":"Genes down-regulated in MDA-MB-231 cells (breast cancer) after knockdown of PRKCA and ETS1 [GeneID=5578;2113] by RNAi."} {"geneset":"DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP","description":"Genes up-regulated in Kasumi-1 cells (acute myeloid leukaemia (AML) with the t(8;21) translocation) after knockdown of the AML1 MTG8 fusion [GeneID=861;862] by RNAi."} {"geneset":"DUNNE_TARGETS_OF_AML1_MTG8_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DUNNE_TARGETS_OF_AML1_MTG8_FUSION_DN","description":"Genes down-regulated in Kasumi-1 cells (acute myeloid leukaemia (AML) with the t(8;21) translocation) after knockdown of the AML1 MTG8 fusion [GeneID=861;862] by RNAi."} {"geneset":"LUI_THYROID_CANCER_PAX8_PPARG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUI_THYROID_CANCER_PAX8_PPARG_UP","description":"Top up-regulated genes distinguishing between follicular thyroid carcinoma (FTC) samples by the presence or absence of the PAX8-PPARG [GeneID=7849;5468] fusion protein."} {"geneset":"LUI_THYROID_CANCER_PAX8_PPARG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUI_THYROID_CANCER_PAX8_PPARG_DN","description":"Top down-regulated genes distinguishing between follicular thyroid carcinoma (FTC) samples by the presence or absence of the PAX8-PPARG [GeneID=7849;5468] fusion protein."} {"geneset":"HAMAI_APOPTOSIS_VIA_TRAIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAMAI_APOPTOSIS_VIA_TRAIL_UP","description":"Genes up-regulated in T1 cells (primary melanoma, sensitive to TRAIL [GeneID=8743]) compared to G1 cells (metastatic melanoma, resistant to TRAIL)."} {"geneset":"HAMAI_APOPTOSIS_VIA_TRAIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAMAI_APOPTOSIS_VIA_TRAIL_DN","description":"Genes down-regulated in T1 cells (primary melanoma, sensitive to TRAIL [GeneID=8743]) compared to G1 cells (metastatic melanoma, resistant to TRAIL)."} {"geneset":"OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP","description":"Genes up-regulated in pirmary cultures of epithelial ovarian cancer (EOC): invasive (TOV) vs low malignant potential (LMP) tumors."} {"geneset":"OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_DN","description":"Genes down-regulated in pirmary cultures of epithelial ovarian cancer (EOC): invasive (TOV) vs low malignant potential (LMP) tumors."} {"geneset":"HUMMERICH_BENIGN_SKIN_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUMMERICH_BENIGN_SKIN_TUMOR_UP","description":"Genes up-regulated in benign skin tumors (papilloma) induced by treatment with DMBA and TPA [PubChem=6001;4792] chemicals in the two stage skin carcinogenesis model."} {"geneset":"HUMMERICH_BENIGN_SKIN_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUMMERICH_BENIGN_SKIN_TUMOR_DN","description":"Genes down-regulated in benign skin tumors (papilloma) induced by treatment with DMBA and TPA [PubChem=6001;4792] chemicals in the two stage skin carcinogenesis model."} {"geneset":"MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP","description":"Pubertal genes up-regulated by TGFB1 [GeneID=7040]."} {"geneset":"MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN","description":"Pubertal genes down-regulated by TGFB1 [GeneID=7040]."} {"geneset":"HUMMERICH_MALIGNANT_SKIN_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUMMERICH_MALIGNANT_SKIN_TUMOR_UP","description":"Genes up-regulated in malignant skin tumors (squamous cell carcinoma, SCC) formed by treatment with DMBA and TPA [PubChem=6001;4792] in the two stage skin carcinogenesis model."} {"geneset":"HUMMERICH_MALIGNANT_SKIN_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUMMERICH_MALIGNANT_SKIN_TUMOR_DN","description":"Genes down-regulated in malignant skin tumors (squamous cell carcinoma, SCC) formed by treatment with DMBA and TPA [PubChem=6001;4792] in the two stage skin carcinogenesis model."} {"geneset":"LUCAS_HNF4A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUCAS_HNF4A_TARGETS_UP","description":"Genes up-regulated in Tet-On HEK293 cells (embryonic kidney) by expression of HNF4A [GeneID=3172]."} {"geneset":"LUCAS_HNF4A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUCAS_HNF4A_TARGETS_DN","description":"Genes down-regulated in Tet-On HEK293 cells (embryonic kidney) by expression of HNF4A [GeneID=3172]."} {"geneset":"ZIRN_TRETINOIN_RESPONSE_WT1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZIRN_TRETINOIN_RESPONSE_WT1_UP","description":"Genes up-regulated in MZ128 cells (Wilms tumor with mutated WT1 [GeneID=7490]) after treatment with 10 microM tretinoin (ATRA) [PubChem=444795] for 24 h."} {"geneset":"ZIRN_TRETINOIN_RESPONSE_WT1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZIRN_TRETINOIN_RESPONSE_WT1_DN","description":"Genes down-regulated in MZ128 cells (Wilms tumor with mutated WT1 [GeneID=7490]) after treatment with 10 microM tretinoin (ATRA) [PubChem=444795] for 24 h."} {"geneset":"ZIRN_TRETINOIN_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZIRN_TRETINOIN_RESPONSE_UP","description":"Genes up-regulated in MS427 cells (Wilms tumor with normal WT1 [GeneID=7490]) after treatment with 10 microM tretinoin (ATRA) [PubChem=444795] for 24 h."} {"geneset":"ZIRN_TRETINOIN_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZIRN_TRETINOIN_RESPONSE_DN","description":"Genes down-regulated in MS427 cells (Wilms tumor with normal WT1 [GeneID=7490]) after treatment with 10 microM tretinoin (ATRA) [PubChem=444795] for 24 h."} {"geneset":"STREICHER_LSM1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STREICHER_LSM1_TARGETS_UP","description":"Genes up-regulated in MCF10A cells (breast cancer) by expression of LSM1 [GeneID=27257] off a letiviral vector."} {"geneset":"STREICHER_LSM1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STREICHER_LSM1_TARGETS_DN","description":"Genes down-regulated in MCF10A cells (breast cancer) by expression of LSM1 [GeneID=27257] off a letiviral vector."} {"geneset":"BUSA_SAM68_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BUSA_SAM68_TARGETS_UP","description":"Genes up-regulated in LNCaP cells (prostate cancer) after knockdown of SAM68 [GeneID=10657] by RNAi."} {"geneset":"BUSA_SAM68_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BUSA_SAM68_TARGETS_DN","description":"Genes down-regulated in LNCaP cells (prostate cancer) after knockdown of SAM68 [GeneID=10657] by RNAi."} {"geneset":"KAN_RESPONSE_TO_ARSENIC_TRIOXIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAN_RESPONSE_TO_ARSENIC_TRIOXIDE","description":"Genes changed in U373-MG cells (malignant glioma) upon treatment with arsenic trioxide [PubChem=14888], a chemical that can cause autophagic cell death."} {"geneset":"LANG_MYB_FAMILY_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANG_MYB_FAMILY_TARGETS","description":"Myb family target genes."} {"geneset":"MCBRYAN_TERMINAL_END_BUD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_TERMINAL_END_BUD_UP","description":"The 'TEB profile genes': up-regulated during pubertal mammary gland development specifically in the TEB (terminal end bud) structures."} {"geneset":"MCBRYAN_TERMINAL_END_BUD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCBRYAN_TERMINAL_END_BUD_DN","description":"The 'TEB profile genes': down-regulated during pubertal mammary gland development specifically in the TEB (terminal end bud) structures."} {"geneset":"NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP","description":"Genes up-regulated in K562 cells (bone marrow) after treatment with dasatinib [PubChem=3062316] or imatinib [PubChem=5291]."} {"geneset":"NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_DN","description":"Genes down-regulated in K562 cells (bone marrow) after treatment with dasatinib [PubChem=3062316] or imatinib [PubChem=5291]."} {"geneset":"DARWICHE_SKIN_TUMOR_PROMOTER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_SKIN_TUMOR_PROMOTER_UP","description":"Genes up-regulated during skin tumor progression: epidermis treated with the carcinogen DMBA [PubChem=6001] followed by 20 weekly applications of the tumor promoter TPA [PubChem=4792], compared to the untreated skin."} {"geneset":"DARWICHE_SKIN_TUMOR_PROMOTER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_SKIN_TUMOR_PROMOTER_DN","description":"Genes down-regulated during skin tumor progression: epidermis treated with the carcinogen DMBA [PubChem=6001] followed by 20 weekly applications of the tumor promoter TPA [PubChem=4792], compared to the untreated skin."} {"geneset":"DARWICHE_PAPILLOMA_RISK_LOW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_PAPILLOMA_RISK_LOW_UP","description":"Genes up-regulated during skin tumor progression from low risk papilloma vs normal skin."} {"geneset":"DARWICHE_PAPILLOMA_RISK_LOW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_PAPILLOMA_RISK_LOW_DN","description":"Genes down-regulated during skin tumor progression from low risk papilloma vs normal skin."} {"geneset":"DARWICHE_PAPILLOMA_RISK_HIGH_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_PAPILLOMA_RISK_HIGH_UP","description":"Genes up-regulated during skin tumor progression from normal skin to high risk papilloma."} {"geneset":"DARWICHE_PAPILLOMA_RISK_HIGH_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_PAPILLOMA_RISK_HIGH_DN","description":"Genes down-regulated during skin tumor progression from normal skin to high risk papilloma."} {"geneset":"DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP","description":"Genes up-regulated in squamous cell carcinoma (SCC) compared to normal skin."} {"geneset":"DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN","description":"Genes down-regulated in squamous cell carcinoma (SCC) compared to normal skin."} {"geneset":"MAHADEVAN_IMATINIB_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAHADEVAN_IMATINIB_RESISTANCE_UP","description":"Top genes up-regulated in the GIST (gastrointestinal stromal tumor) cell line resistant to imatinib [PubChem=5291] compared to the parental cell line sensitive to the drug."} {"geneset":"MAHADEVAN_IMATINIB_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAHADEVAN_IMATINIB_RESISTANCE_DN","description":"Top genes down-regulated in the GIST (gastrointestinal stromal tumor) cell line resistant to imatinib [PubChem=5291] compared to the parental cell line sensitive to the drug."} {"geneset":"TOMIDA_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOMIDA_METASTASIS_UP","description":"Up-regulated genes associated with the acquision of metastatic potential in LNM35 cells (large cell lung cancer)."} {"geneset":"TOMIDA_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOMIDA_METASTASIS_DN","description":"Down-regulated genes associated with the acquision of metastatic potential in LNM35 cells (large cell lung cancer)."} {"geneset":"SAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN","description":"Detoxification pathway genes down-regulated in enterocytes of transgenic mice expressing SV40 T antigen."} {"geneset":"OZANNE_AP1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OZANNE_AP1_TARGETS_UP","description":"Cancer motility and invasion genes up-regulated by the AP-1 transcription factor."} {"geneset":"OZANNE_AP1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OZANNE_AP1_TARGETS_DN","description":"Cancer motility and invasion genes down-regulated by the AP-1 transcription factor."} {"geneset":"HWANG_PROSTATE_CANCER_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HWANG_PROSTATE_CANCER_MARKERS","description":"Proteins implicated in prostate carcinogenesis."} {"geneset":"CORRADETTI_MTOR_PATHWAY_REGULATORS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CORRADETTI_MTOR_PATHWAY_REGULATORS_DN","description":"Major antagonists linked to the mTOR [GeneID=2475] signaling network."} {"geneset":"HU_ANGIOGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HU_ANGIOGENESIS_UP","description":"Up-regulated genes that separate angiogenic from non-angiogenic non-small cell lung carcinoma (NSCLC) samples."} {"geneset":"HU_ANGIOGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HU_ANGIOGENESIS_DN","description":"Down-regulated genes that separate angiogenic from non-angiogenic non-small cell lung carcinoma (NSCLC) samples."} {"geneset":"BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP","description":"Genes up-regulated in SaOS-2 cells (osteosarcoma) upon expression of PAX3-FOXO1 [GeneID=5077;2308] fusion protein off an adenoviral vector."} {"geneset":"BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN","description":"Genes down-regulated in SaOS-2 cells (osteosarcoma) upon expression of PAX3-FOXO1 [GeneID=5077;2308] fusion protein off an adenoviral vector."} {"geneset":"DARWICHE_PAPILLOMA_PROGRESSION_RISK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_PAPILLOMA_PROGRESSION_RISK","description":"Genes that classify progression risk of benign papilloma samples: low vs high risk."} {"geneset":"SHIRAISHI_PLZF_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIRAISHI_PLZF_TARGETS_UP","description":"Genes up-regulated in A375 and 397 cells (melanoma) by forced expression of PLZF [GeneID=7704] off adenovirus vector."} {"geneset":"SHIRAISHI_PLZF_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIRAISHI_PLZF_TARGETS_DN","description":"Genes down-regulated in A375 and 397 cells (melanoma) by forced expression of PLZF [GeneID=7704] off adenovirus vector."} {"geneset":"MOTAMED_RESPONSE_TO_ANDROGEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOTAMED_RESPONSE_TO_ANDROGEN_UP","description":"Genes up-regulated in ovarian epithelial cells in response to dihydrotestosterone (DHT) [PubChem=10635]."} {"geneset":"MOTAMED_RESPONSE_TO_ANDROGEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOTAMED_RESPONSE_TO_ANDROGEN_DN","description":"Genes down-regulated in ovarian epithelial cells in response to dihydrotestosterone (DHT) [PubChem=10635]."} {"geneset":"RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_UP","description":"Apoptotic genes dependent on SMAD4 [GeneID=4089] and up-regulated in AML12 cells (hepatocytes) after stimulation with TGFB1 [GeneID=7040]."} {"geneset":"RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_DN","description":"Apoptotic genes dependent on SMAD4 [GeneID=4089] and down-regulated in AML12 cells (hepatocytes) after stimulation with TGFB1 [GeneID=7040]."} {"geneset":"RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_UP","description":"Apoptotic genes dependent on MAPK1 [GeneID=5594] and up-regulated in AML12 cells (hepatocytes) after stimulation with TGFB1 [GeneID=7040]."} {"geneset":"RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN","description":"Apoptotic genes dependent on MAPK1 [GeneID=5594] and down-regulated in AML12 cells (hepatocytes) after stimulation with TGFB1 [GeneID=7040]."} {"geneset":"OLSSON_E2F3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OLSSON_E2F3_TARGETS_UP","description":"Genes up-regulated in the 5637 cell line (bladder cancer) after knockdown of E2F3 [GeneID=1871] by RNAi."} {"geneset":"OLSSON_E2F3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OLSSON_E2F3_TARGETS_DN","description":"Genes down-regulated in the 5637 cell line (bladder cancer) after knockdown of E2F3 [GeneID=1871] by RNAi."} {"geneset":"MARKS_HDAC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARKS_HDAC_TARGETS_UP","description":"Genes whose transcription is up-regulated by histone deacetylase inhibitors."} {"geneset":"MARKS_HDAC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARKS_HDAC_TARGETS_DN","description":"Genes whose transcription is down-regulated by histone deacetylase inhibitors."} {"geneset":"CHOI_ATL_ACUTE_STAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHOI_ATL_ACUTE_STAGE","description":"Acute stage-specific genes for adult T cell leukemia (ATL)."} {"geneset":"CHOI_ATL_STAGE_PREDICTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHOI_ATL_STAGE_PREDICTOR","description":"Genes used to predict the clinical stages of acute T-cell leukemia (ATL): chronic vs acute."} {"geneset":"WONG_ENDMETRIUM_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_ENDMETRIUM_CANCER_UP","description":"Genes up-regulated in cancer endometrium samples compared to the normal endometrium."} {"geneset":"WONG_ENDMETRIUM_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_ENDMETRIUM_CANCER_DN","description":"Genes down-regulated in cancer endometrium samples compared to the normal endometrium."} {"geneset":"WONG_ENDOMETRIAL_CANCER_LATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_ENDOMETRIAL_CANCER_LATE","description":"Genes down-regulated in late stage (stage 3) endometrial cancers compared to the earlier stages (stage 1 and 2)."} {"geneset":"ABDULRAHMAN_KIDNEY_CANCER_VHL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABDULRAHMAN_KIDNEY_CANCER_VHL_UP","description":"Genes up-regulated in the RCC4 cells (renal cell carcinoma, RCC) expressing VHL [GeneID=7428] mutants Type 1 and 2B (associated with RCC) but not those of Type 2A and 2C (not associated with RCC)."} {"geneset":"ABDULRAHMAN_KIDNEY_CANCER_VHL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABDULRAHMAN_KIDNEY_CANCER_VHL_DN","description":"Genes down-regulated in the RCC4 cells (renal cell carcinoma, RCC) expressing VHL [GeneID=7428] mutants Type 1 and 2B (associated with RCC) but not those of Type 2A and 2C (not associated with RCC)."} {"geneset":"KONG_E2F1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KONG_E2F1_TARGETS","description":"Genes up-regulated in MEF cells (embryonic fibroblast) at 16 h after serum stimulation and knockdown of E2F1 [GeneID=1869] by RNAi."} {"geneset":"KONG_E2F3_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KONG_E2F3_TARGETS","description":"Genes up-regulated in MEF cells (embryonic fibroblasts) at 16 hr after serum stimulation and knockdown of E2F3 [GeneID=1871] by RNAi."} {"geneset":"TANAKA_METHYLATED_IN_ESOPHAGEAL_CARCINOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TANAKA_METHYLATED_IN_ESOPHAGEAL_CARCINOMA","description":"Genes with hypermethylated DNA in all four esophageal squamous cell carcinoma (ESCC) lines analyzed."} {"geneset":"EGUCHI_CELL_CYCLE_RB1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EGUCHI_CELL_CYCLE_RB1_TARGETS","description":"RB1 [GeneID=5925] target genes involved in cell cycle regulation: genes down-regulated by doxorubicin [PubChem=31703] only in cells expressing RB1."} {"geneset":"CROSBY_E2F4_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROSBY_E2F4_TARGETS","description":"Putative E2F4 [GeneID=1874] target genes identified as mitotic genes down-regulated in the LNCaP C4-2 cells (prostate cancer) at both 6 and 24 h following irradiation."} {"geneset":"MARKS_ACETYLATED_NON_HISTONE_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARKS_ACETYLATED_NON_HISTONE_PROTEINS","description":"Non-histone proteins that are acetylated."} {"geneset":"IVANOV_MUTATED_IN_COLON_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOV_MUTATED_IN_COLON_CANCER","description":"Genes mutated in colon cancer cell lines, identified using the GINI method described in the paper."} {"geneset":"TAKAYAMA_BOUND_BY_AR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKAYAMA_BOUND_BY_AR","description":"Genes whose promoters bound AR [GeneID=367] in LNCaP cells (prostate cancer) after exposure to the synthetic androgen R1881 [PubChem=13766], based on ChIP-chip analysis."} {"geneset":"RIZ_ERYTHROID_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZ_ERYTHROID_DIFFERENTIATION","description":"Selected gradually up-regulated genes in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts)."} {"geneset":"RIZ_ERYTHROID_DIFFERENTIATION_CCNE1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZ_ERYTHROID_DIFFERENTIATION_CCNE1","description":"Selected gradually up-regulated genes whose expression profile follows that of CCNE1 [GeneID=898] in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts)."} {"geneset":"RIZ_ERYTHROID_DIFFERENTIATION_HBZ","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZ_ERYTHROID_DIFFERENTIATION_HBZ","description":"Selected gradually up-regulated genes whose expression profile follows that of HBZ [GeneID=3050] in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts)."} {"geneset":"CHASSOT_SKIN_WOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHASSOT_SKIN_WOUND","description":"List of the transcription factors up-regulated 1 hr after wounding HDF cells (dermal fibroblasts)."} {"geneset":"LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP","description":"Genes with copy number gains in primary neuroblastoma tumors."} {"geneset":"LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN","description":"Genes with copy number losses in primary neuroblastoma tumors."} {"geneset":"MUELLER_METHYLATED_IN_GLIOBLASTOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MUELLER_METHYLATED_IN_GLIOBLASTOMA","description":"Genes up-regulated in short-term cultured glioblastomas after azacitidine [PubChem=9444] treatment."} {"geneset":"RIZ_ERYTHROID_DIFFERENTIATION_HEMGN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZ_ERYTHROID_DIFFERENTIATION_HEMGN","description":"Selected gradually up-regulated genes whose expression profile follows that of HEMGN [GeneID=55363] in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts)."} {"geneset":"RIZ_ERYTHROID_DIFFERENTIATION_APOBEC2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZ_ERYTHROID_DIFFERENTIATION_APOBEC2","description":"Selected genes whose expression profile follows that of APOBEC2 [GeneID=10930] in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts)."} {"geneset":"RIZ_ERYTHROID_DIFFERENTIATION_6HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZ_ERYTHROID_DIFFERENTIATION_6HR","description":"Selected genes down-regulated in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts) at 6 h time point."} {"geneset":"RIZ_ERYTHROID_DIFFERENTIATION_12HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZ_ERYTHROID_DIFFERENTIATION_12HR","description":"Selected genes down-regulated in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts) at 12 h time point."} {"geneset":"EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP","description":"Genes up-regulated in Rh4 cells (alveolar rhabdomyosarcoma, ARMS) after knockdown of the PAX3-FOXO1 [GeneiD=5077;2308] fusion protein by RNAi for 72 hr."} {"geneset":"PEREZ_TP53_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEREZ_TP53_TARGETS","description":"Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of TP53 [GeneID=7157] off adenoviral vector."} {"geneset":"PEREZ_TP63_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEREZ_TP63_TARGETS","description":"Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of the transcriptionally active isoform of TP63 [GeneID=8626] off adenoviral vector."} {"geneset":"PEREZ_TP53_AND_TP63_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEREZ_TP53_AND_TP63_TARGETS","description":"Genes up-regulated in HMEC cells (primary mammary epithelium) upon expression of both of TP53 [GeneID=7157] and the transcriptionally active isoform of TP63 [GeneID=8626] off adenoviral vectors."} {"geneset":"WAKASUGI_HAVE_ZNF143_BINDING_SITES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAKASUGI_HAVE_ZNF143_BINDING_SITES","description":"DNA repair genes whose promoters contain putative ZNF143 [GeneID=7702] binding sites."} {"geneset":"RODRIGUES_NTN1_AND_DCC_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODRIGUES_NTN1_AND_DCC_TARGETS","description":"Genes down-regulated in HCT8/S11 cells (colon cancer) which lack DCC [GeneID=9423] and stably express NTN1 [GeneID=1630]."} {"geneset":"DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP","description":"Genes exclusively up-regulated in fibroblasts expressing the XP/CS mutant form of ERCC3 [GeneID=2071] after high dose UVC irradiation."} {"geneset":"DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN","description":"Genes exclusively down-regulated in fibroblasts expressing the XP/CS mutant form of ERCC3 [GeneID=2071] after high dose UVC irradiation."} {"geneset":"DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_UP","description":"Genes exclusively up-regulated in fibroblasts expressing the TTD mutant form of ERCC3 [GeneID=2071], after UVC irradiation."} {"geneset":"DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN","description":"Genes exclusively down-regulated in fibroblasts expressing the TTD mutant form of ERCC3 [GeneID=2071], after UVC irradiation."} {"geneset":"TURJANSKI_MAPK1_AND_MAPK2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURJANSKI_MAPK1_AND_MAPK2_TARGETS","description":"Examples of transcription factors whose activities are regulated by MAPK1 and MAPK3 [GeneID=5594;5595] phosphorylation."} {"geneset":"TURJANSKI_MAPK8_AND_MAPK9_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURJANSKI_MAPK8_AND_MAPK9_TARGETS","description":"Examples of transcription factors whose activities are regulated by MAPK8 and MAPK9 [GeneID=5599;5601]."} {"geneset":"TURJANSKI_MAPK7_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURJANSKI_MAPK7_TARGETS","description":"Examples of transcription factors whose activities are regulated by MAPK7 [GeneID=5598] phosphorylation."} {"geneset":"TURJANSKI_MAPK11_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURJANSKI_MAPK11_TARGETS","description":"Examples of transcription factors whose activities are regulated by MAPK11 [GeneID=5600] phosphorylation."} {"geneset":"TURJANSKI_MAPK14_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TURJANSKI_MAPK14_TARGETS","description":"Examples of transcription factors whose activities are regulated by MAPK14 [GeneID=1432] phosphorylation."} {"geneset":"MAHADEVAN_GIST_MORPHOLOGICAL_SWITCH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAHADEVAN_GIST_MORPHOLOGICAL_SWITCH","description":"Genes up-regulated in the GIST (gastrointestinal stromal tumor) cell line resistant to imatinib [PubChem=5291] that may correlate with the morphological switch in these cells."} {"geneset":"MAHADEVAN_RESPONSE_TO_MP470_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAHADEVAN_RESPONSE_TO_MP470_DN","description":"Bottom genes down-regulated in the GIST (gastrointestinal stromal tumor) cell line sensitive to imatinib [PubChem=5291] after treatment with MP470, a protein kinase inhibitor."} {"geneset":"MAHADEVAN_RESPONSE_TO_MP470_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAHADEVAN_RESPONSE_TO_MP470_UP","description":"Top genes up-regulated in the GIST (gastrointestinal stromal tumor) cell line resistant to imatinib [PubChem=5291] after treatment with MP470, a protein kinase inhibitor."} {"geneset":"APPIERTO_RESPONSE_TO_FENRETINIDE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/APPIERTO_RESPONSE_TO_FENRETINIDE_UP","description":"Genes up-regulated in A2780 cells (ovarian carcinoma) exposed to fenretinide [PubChem=1744]."} {"geneset":"APPIERTO_RESPONSE_TO_FENRETINIDE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/APPIERTO_RESPONSE_TO_FENRETINIDE_DN","description":"Genes down-regulated in A2780 cells (ovarian carcinoma) exposed to fenretinide [PubChem=1744]."} {"geneset":"NAGY_TFTC_COMPONENTS_HUMAN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAGY_TFTC_COMPONENTS_HUMAN","description":"Composition of the 2 MDa human TFTC complex containing KAT2A [GeneID=2648]."} {"geneset":"NAGY_STAGA_COMPONENTS_HUMAN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAGY_STAGA_COMPONENTS_HUMAN","description":"Composition of the 2 MDa human STAGA complex containing KAT2A [GeneID=2648]."} {"geneset":"NAGY_PCAF_COMPONENTS_HUMAN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAGY_PCAF_COMPONENTS_HUMAN","description":"Composition of the 2 MDa human PCAF complex."} {"geneset":"BAKER_HEMATOPOESIS_STAT1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAKER_HEMATOPOESIS_STAT1_TARGETS","description":"STAT1 [GeneID=6772] targets in hematopoetic signaling."} {"geneset":"BAKER_HEMATOPOIESIS_STAT3_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAKER_HEMATOPOIESIS_STAT3_TARGETS","description":"STAT3 [GeneID=6774] targets in hematopoietic signaling."} {"geneset":"BAKER_HEMATOPOESIS_STAT5_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAKER_HEMATOPOESIS_STAT5_TARGETS","description":"STAT5 [GeneID=6777] targets in hematopoietic signaling."} {"geneset":"SEIDEN_MET_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEIDEN_MET_SIGNALING","description":"Genes down-regulated both in vivo and in vitro upon activation of MET [GeneID=4233] signaling."} {"geneset":"AUNG_GASTRIC_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AUNG_GASTRIC_CANCER","description":"Selected genes specifically expressed in gastric cancer."} {"geneset":"SANCHEZ_MDM2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANCHEZ_MDM2_TARGETS","description":"Genes up-regulated in BJ cells (forskin fibroblasts) upon overexpression of the most abundant alternative splicing forms of MDM2 [GeneID=4193], HDM2-A and HDM2-B, off a retroviral vector."} {"geneset":"BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER","description":"Growth factor signaling components up-regulated in hepatocellular carcinoma (HCC)."} {"geneset":"NAKAMURA_LUNG_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_LUNG_CANCER","description":"Genes up-regulated in lung adenocarcinoma cell lines and not expressed in non-cancerous lung epithelial cells."} {"geneset":"GALLUZZI_PERMEABILIZE_MITOCHONDRIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALLUZZI_PERMEABILIZE_MITOCHONDRIA","description":"Proteins that permeabilize mitochondria."} {"geneset":"HAEGERSTRAND_RESPONSE_TO_IMATINIB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAEGERSTRAND_RESPONSE_TO_IMATINIB","description":"Genes with the highest differential expression in primary tissue cultures of high grade glioma: responders vs non-responders to imatinib [PubChem=5291] treatment."} {"geneset":"MATHEW_FANCONI_ANEMIA_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATHEW_FANCONI_ANEMIA_GENES","description":"Genes identified with the Fanconi anemia (FA) and the FA pathway."} {"geneset":"MIDORIKAWA_AMPLIFIED_IN_LIVER_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIDORIKAWA_AMPLIFIED_IN_LIVER_CANCER","description":"Candidate genes in genomic amplification regions in hepatocellular carcinoma (HCC) samples."} {"geneset":"GILMORE_CORE_NFKB_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GILMORE_CORE_NFKB_PATHWAY","description":"Genes encoding the NF-kB core signaling proteins."} {"geneset":"SCHEIDEREIT_IKK_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHEIDEREIT_IKK_TARGETS","description":"Genes encoding substrates of IkappaB kinase (IKK) complex."} {"geneset":"DUTTA_APOPTOSIS_VIA_NFKB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DUTTA_APOPTOSIS_VIA_NFKB","description":"NF-kB target genes involved in the regulation of programmed cell death."} {"geneset":"DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS","description":"NF-kB-driven pro-inflammatory genes that are negatively regulated by glucocorticoids."} {"geneset":"ROVERSI_GLIOMA_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROVERSI_GLIOMA_COPY_NUMBER_DN","description":"Genes in the most frequently homozygous deleted loci in a panel of glioma cell lines."} {"geneset":"SEIDEN_ONCOGENESIS_BY_MET","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEIDEN_ONCOGENESIS_BY_MET","description":"Genes changed in xenograft tumors formed by DLD-1 or DKO-4 cells (colon cancer) overexpressing MET [GeneID=4233]."} {"geneset":"HUMMERICH_SKIN_CANCER_PROGRESSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUMMERICH_SKIN_CANCER_PROGRESSION_UP","description":"Selected genes up-regulated during progression through benign to malignant skin tumors formed by treatment with DMBA and TPA [PubChem=6001;4792] chemicals in the two stage skin carcinogenesis model."} {"geneset":"HUMMERICH_SKIN_CANCER_PROGRESSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUMMERICH_SKIN_CANCER_PROGRESSION_DN","description":"Selected genes down-regulated during progression through benign to malignant skin tumors formed by treatment with DMBA and TPA [PubChem=6001;4792] chemicals in the two stage skin carcinogenesis model."} {"geneset":"CAVARD_LIVER_CANCER_MALIGNANT_VS_BENIGN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAVARD_LIVER_CANCER_MALIGNANT_VS_BENIGN","description":"Genes identified by subtractive hybridization comparing malignant and benign components of a hepatocellular carcinoma (HCC) in a pre-existing liver adenoma in a morphologically normal liver."} {"geneset":"KLEIN_TARGETS_OF_BCR_ABL1_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KLEIN_TARGETS_OF_BCR_ABL1_FUSION","description":"Genes changed in pre-B lymphoblastic leukemia cells with BCR-ABL1 fusion [GeneID=613, 25] vs normal pre-B lymphocytes."} {"geneset":"ROVERSI_GLIOMA_LOH_REGIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROVERSI_GLIOMA_LOH_REGIONS","description":"Genes in the most frequently heterozygous deleted loci of a panel of glioma cell lines."} {"geneset":"ROVERSI_GLIOMA_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROVERSI_GLIOMA_COPY_NUMBER_UP","description":"Genes in the most frequently gained loci in a panel of glioma cell lines."} {"geneset":"RASHI_RESPONSE_TO_IONIZING_RADIATION_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RASHI_RESPONSE_TO_IONIZING_RADIATION_1","description":"Cluster 1: ATM [GeneID=472] dependent genes induced at 30 min after ionizing radiation treatment."} {"geneset":"RASHI_RESPONSE_TO_IONIZING_RADIATION_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RASHI_RESPONSE_TO_IONIZING_RADIATION_2","description":"Cluster 2: late ATM [GeneID=472] dependent genes induced by ionizing radiation treatment."} {"geneset":"RASHI_RESPONSE_TO_IONIZING_RADIATION_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RASHI_RESPONSE_TO_IONIZING_RADIATION_3","description":"Cluster 3: genes activated by ionizing radiation regardless of ATM [GeneID=472] status."} {"geneset":"RASHI_RESPONSE_TO_IONIZING_RADIATION_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RASHI_RESPONSE_TO_IONIZING_RADIATION_4","description":"Cluster 4: genes repressed by ionizing radiation regardless of ATM [GeneID=472] status."} {"geneset":"RASHI_RESPONSE_TO_IONIZING_RADIATION_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RASHI_RESPONSE_TO_IONIZING_RADIATION_5","description":"Cluster 5: early responding genes activated in ATM [GeneID=472] deficient but not in the wild type tissues."} {"geneset":"RASHI_RESPONSE_TO_IONIZING_RADIATION_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RASHI_RESPONSE_TO_IONIZING_RADIATION_6","description":"Cluster 6: late responding genes activated in ATM [GeneID=472] deficient but not in the wild type tissues."} {"geneset":"RASHI_NFKB1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RASHI_NFKB1_TARGETS","description":"Known and putative targets of NFKB1 [GeneID=4790] identified among the ATM [GeneID=472] dependent, late responders to ionizing radiation."} {"geneset":"IWANAGA_E2F1_TARGETS_INDUCED_BY_SERUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IWANAGA_E2F1_TARGETS_INDUCED_BY_SERUM","description":"Genes up-regulated in REF52 cells (embryonic fibroblast) by expression of E2F1 [GeneID=1869] that were also induced at 16 hr after serum stimulation."} {"geneset":"AIGNER_ZEB1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AIGNER_ZEB1_TARGETS","description":"Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of ZEB1 [GeneID=6935] by RNAi."} {"geneset":"SUZUKI_AMPLIFIED_IN_ORAL_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUZUKI_AMPLIFIED_IN_ORAL_CANCER","description":"High-level amplifications detected in oral squamous cell carcinoma (OSCC) lines by array-CGH analysis."} {"geneset":"HESSON_TUMOR_SUPPRESSOR_CLUSTER_3P21_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HESSON_TUMOR_SUPPRESSOR_CLUSTER_3P21_3","description":"Genes in the tumor suppressor cluster of the 3p21.3 region."} {"geneset":"MARTIN_INTERACT_WITH_HDAC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTIN_INTERACT_WITH_HDAC","description":"Interaction partners of class IIa histone deacetylases (HDAC)."} {"geneset":"LASTOWSKA_COAMPLIFIED_WITH_MYCN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LASTOWSKA_COAMPLIFIED_WITH_MYCN","description":"Genes co-amplified within MYCN [GeneID=4613] in primary neuroblastoma tumors."} {"geneset":"IWANAGA_E2F1_TARGETS_NOT_INDUCED_BY_SERUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IWANAGA_E2F1_TARGETS_NOT_INDUCED_BY_SERUM","description":"Genes up-regulated in REF52 cells (embryonic fibroblast) by expression of E2F1 [GeneID=1869] that were not induced at all at 16 hr after serum stimulation."} {"geneset":"LI_LUNG_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_LUNG_CANCER","description":"Proteins showing significant overexpression in lung cancer cell lines relative to normal bronchial epithelial cell lines."} {"geneset":"LI_AMPLIFIED_IN_LUNG_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_AMPLIFIED_IN_LUNG_CANCER","description":"Genes with increased copy number that correlates with increased expression across six different lung adenocarcinoma cell lines."} {"geneset":"LINDGREN_BLADDER_CANCER_CLUSTER_2B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_CLUSTER_2B","description":"Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors."} {"geneset":"LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE","description":"Genes up-regulated among the high recurrence rate urothelial cell carcinoma (UCC) tumors."} {"geneset":"LINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q","description":"Genes down-regulated in urothelial cell carcinoma (UCC) tumors with LOH on 9q as compared to the tumors showing retention."} {"geneset":"NAKAMURA_ALVEOLAR_EPITHELIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_ALVEOLAR_EPITHELIUM","description":"Differentiation markers for normal alveolar epithelium cells."} {"geneset":"NAKAMURA_BRONCHIAL_AND_BRONCHIOLAR_EPITHELIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_BRONCHIAL_AND_BRONCHIOLAR_EPITHELIA","description":"Differentiation markers for normal bronchiolar and bronchial epithelial cells."} {"geneset":"NAKAMURA_LUNG_CANCER_DIFFERENTIATION_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_LUNG_CANCER_DIFFERENTIATION_MARKERS","description":"14 candidate differentiation markers in lung adenocarcinoma cells, noncancerous lung cells and peripheral blood cells."} {"geneset":"GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION","description":"Proteins acting on mitochondria to prevent membrane permeabilization."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_17","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_17","description":"Amplification hot spot 17: colocalized fragile sites and cancer genes in the 1q11-q44 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_24","description":"Amplification hot spot 24: colocalized fragile sites and cancer genes in the 1q21-q24 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_25","description":"Amplification hot spot 25: colocalized fragile sites and cancer genes in the 2q13-q36 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7","description":"Amplification hot spot 7: colocalized fragile sites and cancer genes in the 3q26.3-q29 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_27","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_27","description":"Amplification hot spot 27: colocalized fragile sites and cancer genes in the 5p15.3-p15.1; 5p12-q35 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_15","description":"Amplification hot spot 15: colocalized fragile sites and cancer genes in the 6p25-p11.1 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_29","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_29","description":"Amplification hot spot 29: colocolized fragile sites and cancer genes in the 7p22-p13 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_9","description":"Amplification hot spot 9: colocolized fragile sites and cancer genes in the 8p23-q12; 8q23 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_16","description":"Amplification hot spot 16: colocolized fragile sites and cancer genes in the 8q11.1-q24.3 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_14","description":"Amplification hot spot 14: colocolized fragile sites and cancer genes in the 8q24.1-q24.3 region."} {"geneset":"EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN","description":"Genes down-regulated in Rh4 cells (alveolar rhabdomyosarcoma, ARMS) after knockdown of the PAX3-FOXO1 [GeneiD=5077;2308] fusion protein by RNAi for 72 hr."} {"geneset":"EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION","description":"Muscle development genes up-regulated in Rh4 cells (alveolar rhabdomyosarcoma, ARMS) but not in the RD cells (embryonal rhabdomyosarcoma, ERMS) after knockdown of PAX3-FOXO1 [GeneID=5077;2308] fusion by RNAi for 72 hr."} {"geneset":"SCHAVOLT_TARGETS_OF_TP53_AND_TP63","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAVOLT_TARGETS_OF_TP53_AND_TP63","description":"Genes up-regulated by TP53 [GeneID=7157] and down-regulated by an isoform of TP63 [GeneID=8626] in primary HEK cells (epidermal keratinocytes)."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_8","description":"Amplification hot spot 8: colocolized fragile sites and cancer genes in the 9q11-34 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_23","description":"Amplification hot spot 23: colocolized fragile sites and cancer genes in the 11q12-q25 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_11","description":"Amplification hot spot 11: colocolized fragile sites and cancer genes in the 11q3 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_2","description":"Amplification hot spot 2: colocolized fragile sites and cancer genes in the 12p13-p11.1 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_21","description":"Amplification hot spot 21: colocolized fragile sites and cancer genes in the 12q13-q21 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_30","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_30","description":"Amplification hot spot 30: colocolized fragile sites and cancer genes in the 12q21-q24.3 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_3","description":"Amplification hot spot 3: colocolized fragile sites and cancer genes in the 15q21-q26 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_6","description":"Amplification hot spot 6: colocolized fragile sites and cancer genes in the 17p13-p11.1 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_12","description":"Amplification hot spot 12: colocolized fragile sites and cancer genes in the 17q11.1-q21; 17q25 region."} {"geneset":"MATTIOLI_MGUS_VS_PCL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATTIOLI_MGUS_VS_PCL","description":"Genes changed in MGUS (monoclonal gammopathy of undetermined significance) compared to PCL (plasma cell leukemia) samples."} {"geneset":"MATTIOLI_MGUS_VS_MULTIPLE_MYELOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATTIOLI_MGUS_VS_MULTIPLE_MYELOMA","description":"Genes distinguishing between MGUS (monoclonal gammopathy of undetermined significance) and multiple myeloma (MM) samples."} {"geneset":"FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL","description":"Genes which best discriminate between two groups of breast cancer according to the status of ESR1 and AR [GeneID=2099;367]: apocrine (ESR1- AR+) and luminal (ESR1+ AR+)."} {"geneset":"FARMER_BREAST_CANCER_APOCRINE_VS_BASAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_APOCRINE_VS_BASAL","description":"Genes which best discriminate between two groups of breast cancer according the status of ESR1 and AR [GeneID=2099;367]: apocrine (ESR1- AR+) vs basal (ESR1- AR-)."} {"geneset":"FARMER_BREAST_CANCER_BASAL_VS_LULMINAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_BASAL_VS_LULMINAL","description":"Genes which best discriminated between two groups of breast cancer according to the status of ESR1 and AR [GeneID=2099;367]: basal (ESR1- AR-) and luminal (ESR1+ AR+)."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_5","description":"Amplification hot spot 5: colocolized fragile sites and cancer genes in the 17q22-q25 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_18","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_18","description":"Amplification hot spot 18: colocolized fragile sites and cancer genes in the 18q11.2-q23 region."} {"geneset":"LUI_THYROID_CANCER_CLUSTER_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUI_THYROID_CANCER_CLUSTER_1","description":"Cluster 1: genes with similar expression profiles across follicular thyrorid carcinoma (FTC) samples."} {"geneset":"LUI_THYROID_CANCER_CLUSTER_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUI_THYROID_CANCER_CLUSTER_2","description":"Cluster 2: genes with similar expression profiles across follicular thyroid carcinoma (FTC) samples."} {"geneset":"LUI_THYROID_CANCER_CLUSTER_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUI_THYROID_CANCER_CLUSTER_3","description":"Cluster 3: genes with similar expression profiles across follicular thyrorid carcinoma (FTC) samples; genes in this cluster correlated well with the presence of PAX8-PPARG [GeneID=7849;5468] fusion protein."} {"geneset":"LUI_THYROID_CANCER_CLUSTER_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUI_THYROID_CANCER_CLUSTER_4","description":"Cluster 4: genes with similar expression profiles across follicular thyroid carcinoma (FTC) samples."} {"geneset":"LUI_THYROID_CANCER_CLUSTER_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUI_THYROID_CANCER_CLUSTER_5","description":"Cluster 5: genes with similar expression profiles across follicular thyroid carcinoma (FTC) samples."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_22","description":"Amplification hot spot 22: colocolized fragile sites and cancer genes in the 22q11.1-q13s region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_1","description":"Amplification hot spot 1: colocolized fragile sites and cancer genes in the Xp22.3-p11.1 region."} {"geneset":"MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_13","description":"Amplification hot spot 13: colocolized fragile sites and cancer genes in the Xq12-q28 region."} {"geneset":"GRASEMANN_RETINOBLASTOMA_WITH_6P_AMPLIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRASEMANN_RETINOBLASTOMA_WITH_6P_AMPLIFICATION","description":"Genes changed in retinoblastoma tumors with respect to chromosome 6p amplifications."} {"geneset":"LUI_TARGETS_OF_PAX8_PPARG_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUI_TARGETS_OF_PAX8_PPARG_FUSION","description":"Genes down-regulated in follicular thyroid carcinoma (FTC) samples that bear PAX8-PPARG [GeneID=7849;5468] fusion protein."} {"geneset":"SCHLOSSER_SERUM_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLOSSER_SERUM_RESPONSE_UP","description":"Cluster 1: genes up-regulated in B493-6 cells (B lymphocytes) upon serum stimulation but not by affected by MYC [GeneID=4609]."} {"geneset":"SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC","description":"Cluster 2: genes up-regulated in B493-6 cells (B lymphocytes) by serum alone or in combination with MYC [GeneID=4609] but not by MYC alone."} {"geneset":"SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY","description":"Cluster 3: genes strongly up-regulated in B493-6 cells (B lymphocytes) by a combination of MYC [GeneID=4609] and serum but not by each of them alone."} {"geneset":"SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM","description":"Cluster 7: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [GeneID=4609] and down-regulated by the combination of MYC and serum."} {"geneset":"SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN","description":"Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [GeneID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone."} {"geneset":"SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP","description":"Cluster 5: genes up-regulated in B493-6 cells (B lymphocytes) by MYC [GeneID=4609] alone or in combination with serum but not by serum alone."} {"geneset":"SCHLOSSER_SERUM_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLOSSER_SERUM_RESPONSE_DN","description":"Cluster 4: genes down-regulated in B493-6 cells (B lymphocytes) upon serum stimulation but not affected by MYC [GeneID=4609]."} {"geneset":"MATTIOLI_MULTIPLE_MYELOMA_SUBGROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATTIOLI_MULTIPLE_MYELOMA_SUBGROUPS","description":"Genes differentially expressed in multiple myeloma (MM) patients: comparison of MGUS-like vs PCL-like samples; MGUS=monoclonal gammopathy of undetermined significance, PCL=plasma cell leukemia."} {"geneset":"MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS","description":"Genes expressed in multiple myeloma (MM) patients carrying specific translocations involving the immunoglobulin heavy chain (IGH) locus at 14q32."} {"geneset":"FARMER_BREAST_CANCER_CLUSTER_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_CLUSTER_1","description":"Cluster 1: interferon, T and B lymphocyte genes clustered together across breast cancer samples."} {"geneset":"FARMER_BREAST_CANCER_CLUSTER_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_CLUSTER_8","description":"Cluster 8: selected ERBB2 [GeneID=2064] amplicon genes clustered together across breast cancer samples."} {"geneset":"FARMER_BREAST_CANCER_CLUSTER_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_CLUSTER_7","description":"Cluster 7: selected apocrine and luminal genes clustered together across breast cancer samples."} {"geneset":"FARMER_BREAST_CANCER_CLUSTER_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_CLUSTER_2","description":"Cluster 2: selected proliferation and 8q amplicon genes clustered together across breast cancer samples."} {"geneset":"ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER","description":"The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome."} {"geneset":"SCHEIDEREIT_IKK_INTERACTING_PROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHEIDEREIT_IKK_INTERACTING_PROTEINS","description":"Genes encoding IkappaB kinase (IKK) interacting proteins."} {"geneset":"JAERVINEN_AMPLIFIED_IN_LARYNGEAL_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAERVINEN_AMPLIFIED_IN_LARYNGEAL_CANCER","description":"Genes whose expression was increased due to copy number gain in laryngeal cancer tumors (both in primary cultures and cell lines)."} {"geneset":"HEIDENBLAD_AMPLIFIED_IN_SOFT_TISSUE_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEIDENBLAD_AMPLIFIED_IN_SOFT_TISSUE_CANCER","description":"Genes from selected recurrently amplified regions in soft tissue tumors with supernumerary ring chromosomes."} {"geneset":"HEIDENBLAD_AMPLIFIED_IN_BONE_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEIDENBLAD_AMPLIFIED_IN_BONE_CANCER","description":"Genes from selected recurrently amplified regions in bone tissue tumors with supernumerary ring chromosomes."} {"geneset":"OHASHI_AURKA_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OHASHI_AURKA_TARGETS","description":"Candidate substrate proteins of AURKA [GeneID=6790]."} {"geneset":"OHASHI_AURKB_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OHASHI_AURKB_TARGETS","description":"Candidate substrate proteins of AURKB [GeneID=9212]."} {"geneset":"KOBAYASHI_RESPONSE_TO_ROMIDEPSIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOBAYASHI_RESPONSE_TO_ROMIDEPSIN","description":"Genes up-regulated in MM-LH cells (malignant melanoma) after treatment with the HDAC inhibitor romidepsin (FK228) [PubChem=5352062]."} {"geneset":"LA_MEN1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LA_MEN1_TARGETS","description":"Genes up-regulated in cells expressing MEN1 [GeneID=4221]."} {"geneset":"KOMMAGANI_TP63_GAMMA_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOMMAGANI_TP63_GAMMA_TARGETS","description":"Genes changed in H1299 cells (non-small cell lung cancer, NSCLC) transiently transfected to express the TP63 [GeneID=8626] gamma splice variant."} {"geneset":"LUND_SILENCED_BY_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUND_SILENCED_BY_METHYLATION","description":"Genes up-regulated in FE-8 cells (fibroblasts) upon treatment with azacitidine [PubChem=9444]."} {"geneset":"HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2","description":"Genes distinguishing between breast cancer tumors bearing mutations in BRCA1 [GeneID=672] and those with mutated BRCA2 [GeneID=675]."} {"geneset":"PATTERSON_DOCETAXEL_RESISTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PATTERSON_DOCETAXEL_RESISTANCE","description":"Genes up-regulated in DU145-RD cells (prostate cancer) resistant to docetaxel [PubChem=148124] vs the parental, docetaxel-sensitive cells."} {"geneset":"BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX","description":"Genes up-regulated by growing HMEC-E6 cells (mammary epithelial cells damaged by expression of HPV-16 E6 [GeneID=1489078]) in extracellular matrix (ECM)."} {"geneset":"BOWIE_RESPONSE_TO_TAMOXIFEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOWIE_RESPONSE_TO_TAMOXIFEN","description":"Genes up-regulated by tamoxifen [PubChem=5376] in HMEC-E6 cells (mammary epithelial cells damaged by expression of HPV-16 E6 [GeneID=1489078])."} {"geneset":"AIYAR_COBRA1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AIYAR_COBRA1_TARGETS_UP","description":"Genes up-regulated in T47D cells (breast cancer) after COBRA1 [GeneID=25920] knockdown by RNAi."} {"geneset":"AIYAR_COBRA1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AIYAR_COBRA1_TARGETS_DN","description":"Genes down-regulated in T47D cells (breast cancer) after COBRA1 [GeneID=25920] knockdown by RNAi."} {"geneset":"LI_CISPLATIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_CISPLATIN_RESISTANCE_DN","description":"Genes consistently down-regulated in ACRP cells (ovarian cancer, resistant to cisplatin [PubChem=2767]) compared to the parental sensitive A2780 cells, regardless of cisplatin exposure."} {"geneset":"LI_CISPLATIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_CISPLATIN_RESISTANCE_UP","description":"Genes consistently up-regulated in ACRP cells (ovarian cancer, resistant to cisplatin [PubChem=2767]) compared to the parental sensitive A2780 cells, regardless of cisplatin exposure."} {"geneset":"HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP","description":"Genes up-regulated in MCF7 cells (breast cancer, normal TP53 [GeneID=7157]) undergoing aberrant mitosis and necrosis after treatment wiht 4 nM docetaxel [PubChem=148124]."} {"geneset":"HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_DN","description":"Genes down-regulated in MCF7 cells (breast cancer, normal TP53 [GeneID=7157]) undergoing aberrant mitosis and necrosis after treatment wiht 4 nM docetaxel [PubChem=148124]."} {"geneset":"HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP","description":"Genes up-regulated in MCF7 cells (breast cancer, normal TP53 [GeneID=7157]) undergoing mitotic arrest and apoptosis after treatment with 100 nM docetaxel [PubChem=148124]."} {"geneset":"HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN","description":"Genes down-regulated in MCF7 cells (breast cancer, normal TP53 [GeneID=7157]) undergoing mitotic arrest and apoptosis after treatment with 100 nM docetaxel [PubChem=148124]."} {"geneset":"HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP","description":"Genes up-regulated in MDA-MB-231 cells (breast cancer, mutated TP53 [GeneID=7157]) undergoing aberrant mitosis and necrosis after treatment with 2 nM docetaxel [PubChem=148124]."} {"geneset":"HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_DN","description":"Genes down-regulated in MDA-MB-231 cells (breast cancer, mutated TP53 [GeneID=7157]) undergoing aberrant mitosis and necrosis after treatment with 2 nM docetaxel [PubChem=148124]."} {"geneset":"HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP","description":"Genes up-regulated in MDA-MB-231 cells (breast cancer, mutated TP53 [GeneID=7157]) undergoing mitotic arrest and apoptosis after treatment with 100 nM docetaxel [PubChem=148124]."} {"geneset":"HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN","description":"Genes down-regulated in MDA-MB-231 cells (breast cancer, mutated TP53 [GeneID=7157]) undergoing mitotic arrest and apoptosis after treatment with 100 nM docetaxel [PubChem=148124]."} {"geneset":"XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR","description":"Genes changed similarly in DU-145 cells (prostate cancer) in the absence and presence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 6 h."} {"geneset":"XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR","description":"Genes changed in DU-145 cells (prostate cancer) in the absence but not presence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 6 h."} {"geneset":"XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP","description":"Genes up-regulated in DU-145 cells (prostate cancer) in the absence and presence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 48 h."} {"geneset":"XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_DN","description":"Genes down-regulated in DU-145 cells (prostate cancer) in the absence and presence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 48 h."} {"geneset":"XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP","description":"Genes up-regulated in DU-145 cells (prostate cancer) in the absence but not in the presence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 48 h."} {"geneset":"XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN","description":"Genes down-regulated in DU-145 cells (prostate cancer) in the absence but not in the presence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 48 h."} {"geneset":"XU_HGF_TARGETS_REPRESSED_BY_AKT1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_HGF_TARGETS_REPRESSED_BY_AKT1_UP","description":"Genes up-regulated in DU-145 cells (prostate cancer) in the presence but not in the absence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 48 h."} {"geneset":"XU_HGF_TARGETS_REPRESSED_BY_AKT1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_HGF_TARGETS_REPRESSED_BY_AKT1_DN","description":"Genes down-regulated in DU-145 cells (prostate cancer) in the presence but not in the absence of a dominant negative form of AKT1 [GeneID=207] upon exposure to HGF [GeneID=3082] for 48 h."} {"geneset":"XU_AKT1_TARGETS_6HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_AKT1_TARGETS_6HR","description":"Genes up-regulated in DU-145 cells (prostate cancer) expressing a dominant negative form of AKT1 [GeneID=207] upon sham-treatment for 6 h (as a control for the HGF [GeneID=3082] experiments)."} {"geneset":"XU_AKT1_TARGETS_48HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_AKT1_TARGETS_48HR","description":"Genes up-regulated in DU-145 cells (prostate cancer) expressing a dominant negative form of AKT1 [GeneID=207] upon sham-treatment for 48 h (as a control for the HGF [GeneID=3082] experiments)."} {"geneset":"SHI_SPARC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHI_SPARC_TARGETS_UP","description":"Genes up-regulated in glioma cell lines after knockdown of SPARC [GeneID=6678] by RNAi."} {"geneset":"SHI_SPARC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHI_SPARC_TARGETS_DN","description":"Genes down-regulated in glioma cell lines after knockdown of SPARC [GeneID=6678] by RNAi."} {"geneset":"WAESCH_ANAPHASE_PROMOTING_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAESCH_ANAPHASE_PROMOTING_COMPLEX","description":"Subunits of the anaphase promoting complex (APC)."} {"geneset":"AGARWAL_AKT_PATHWAY_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGARWAL_AKT_PATHWAY_TARGETS","description":"Angiogenic and metastatic genes changed in RKO cells (colorectal cancer) upon perturbation of key components of AKT pathway."} {"geneset":"NEBEN_AML_WITH_FLT3_OR_NRAS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NEBEN_AML_WITH_FLT3_OR_NRAS_UP","description":"Genes up-regulated in acute myeloid leukemia (AML) samples with constitutively activated FLT3 [GeneID=2322] or with activating point mutations within NRAS [GeneID=4893]."} {"geneset":"NEBEN_AML_WITH_FLT3_OR_NRAS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NEBEN_AML_WITH_FLT3_OR_NRAS_DN","description":"Genes down-regulated in acute myeloid leukemia (AML) samples with constitutively activated FLT3 [GeneID=2322] or with activating point mutations within NRAS [GeneID=4893]."} {"geneset":"DIRMEIER_LMP1_RESPONSE_EARLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DIRMEIER_LMP1_RESPONSE_EARLY","description":"Clusters 1 and 2: genes up-regulated in B2264-19/3 cells (primary B lymphocytes) within 30-60 min after activation of LMP1 (an oncogene encoded by Epstein-Barr virus, EBV)."} {"geneset":"EINAV_INTERFERON_SIGNATURE_IN_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EINAV_INTERFERON_SIGNATURE_IN_CANCER","description":"A gene expression signature found in a subset of cancer patients suggestive of a deregulated immune or inflammatory response."} {"geneset":"AMUNDSON_DNA_DAMAGE_RESPONSE_TP53","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMUNDSON_DNA_DAMAGE_RESPONSE_TP53","description":"Genes discriminating TP53 [GeneID=7157] status across various genotoxic stress agents."} {"geneset":"SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS","description":"Genes from the recurrent amplicons in 89 samples of oral squamous cell carcinoma (SCC)."} {"geneset":"NAISHIRO_CTNNB1_TARGETS_WITH_LEF1_MOTIF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAISHIRO_CTNNB1_TARGETS_WITH_LEF1_MOTIF","description":"Genes regulated by CTNNB1 [GeneID=1499] and whose promoters contain binding sites for LEF1 [GeneID=51176]."} {"geneset":"WHITE_NEUROBLASTOMA_WITH_1P36.3_DELETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITE_NEUROBLASTOMA_WITH_1P36.3_DELETION","description":"Genes within the smallest region of consistend deletion (SRD) within 1p36.3 area across a large collection of neuroblastoma cell lines and biopsy samples."} {"geneset":"BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_AND_PAX3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_AND_PAX3","description":"Genes up-regulated in SaOS-2 cells (osteosarcoma) upon expression of PAX3-FOXO1 [GeneID=5077;2308] but down-regulated by PAX3 expression off adenoviral vectors."} {"geneset":"SILIGAN_BOUND_BY_EWS_FLT1_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SILIGAN_BOUND_BY_EWS_FLT1_FUSION","description":"Genes bound by EWSR1-FLT1 [GeneID=2130;2321] fusion but whose expression did not change in STA-ET-7.2 cells (Ewing's sarcoma) after knockdown of EWSR1-FLT1 by RNAi."} {"geneset":"DAUER_STAT3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAUER_STAT3_TARGETS_UP","description":"Top 50 genes up-regulated in A549 cells (lung cancer) expressing STAT3 [GeneID=6774] off an adenovirus vector."} {"geneset":"DAUER_STAT3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAUER_STAT3_TARGETS_DN","description":"Top 50 genes down-regulated in A549 cells (lung cancer) expressing STAT3 [GeneID=6774] off an adenovirus vector."} {"geneset":"PATIL_LIVER_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PATIL_LIVER_CANCER","description":"Genes up-regulated in hepatocellular carcinoma (HCC) compared to normal liver samples."} {"geneset":"KORKOLA_EMBRYONAL_CARCINOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_EMBRYONAL_CARCINOMA","description":"Genes predicting the embryonic carcinoma (EC) subtype of nonseminomatous male germ cell tumors (NSGCT)."} {"geneset":"KORKOLA_TERATOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_TERATOMA","description":"Genes predicting the teratoma (T) subtype of nonseminomatous male germ cell tumors (NSGCT)."} {"geneset":"KORKOLA_YOLK_SAC_TUMOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_YOLK_SAC_TUMOR","description":"Genes predicting the yolk sac tumor (YS) subtype of nonseminomatous male germ cell tumors (NSGCT)."} {"geneset":"KORKOLA_CHORIOCARCINOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_CHORIOCARCINOMA","description":"Genes predicting the choriocarcinoma (CC) of nonseminomatous male germ cell tumors (NSGCT)."} {"geneset":"WANG_METHYLATED_IN_BREAST_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_METHYLATED_IN_BREAST_CANCER","description":"Genes up-regulated in MDA468 cells (breast cancer) vs DU99 cells (normal breast) after treatment with azacytidine [PubChem=9444]."} {"geneset":"HEIDENBLAD_AMPLIFIED_IN_PANCREATIC_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEIDENBLAD_AMPLIFIED_IN_PANCREATIC_CANCER","description":"Genes amplified and up-regulated more than twofold in at least two out of 10 pancreatic cancer cell lines studied."} {"geneset":"TERAMOTO_OPN_TARGETS_CLUSTER_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAMOTO_OPN_TARGETS_CLUSTER_1","description":"Cluster 1: genes whose up-regulation peaked one day after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]."} {"geneset":"TERAMOTO_OPN_TARGETS_CLUSTER_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAMOTO_OPN_TARGETS_CLUSTER_3","description":"Cluster 3: genes whose up-regulation peaked 3 days after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]."} {"geneset":"TERAMOTO_OPN_TARGETS_CLUSTER_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAMOTO_OPN_TARGETS_CLUSTER_4","description":"Cluster 4: genes whose up-regulation peaked 4 days after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]."} {"geneset":"TERAMOTO_OPN_TARGETS_CLUSTER_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAMOTO_OPN_TARGETS_CLUSTER_5","description":"Cluster 5: genes whose up-regulation peaked 5 days after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]."} {"geneset":"TERAMOTO_OPN_TARGETS_CLUSTER_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAMOTO_OPN_TARGETS_CLUSTER_6","description":"Cluster 6: genes exhibiting prolonged up-regulation (>72 h) after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]."} {"geneset":"TERAMOTO_OPN_TARGETS_CLUSTER_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAMOTO_OPN_TARGETS_CLUSTER_7","description":"Cluster 7: genes down-regulated early (within 24 h) after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]."} {"geneset":"TERAMOTO_OPN_TARGETS_CLUSTER_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAMOTO_OPN_TARGETS_CLUSTER_8","description":"Cluster 8: genes showing sustained pattern of down-regulation after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]."} {"geneset":"SCHRAMM_INHBA_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHRAMM_INHBA_TARGETS_UP","description":"Genes up-regulated in Kelly cells (neuroblastoma) by overexpressing INHBA [GeneID=3624] off a plasmid vector."} {"geneset":"SCHRAMM_INHBA_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHRAMM_INHBA_TARGETS_DN","description":"Genes down-regulated in Kelly cells (neuroblastoma) by overexpressing INHBA [GeneID=3624] off a plasmid vector."} {"geneset":"SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP","description":"Genes up-regulated in CT60/4 cells (breast cancer reverted to normal by transfer of chromosome 8p region) vs parental MDA-MB-231 cells (deleted chromosome 8p)."} {"geneset":"SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_DN","description":"Genes down-regulated in CT60/4 cells (breast cancer reverted to normal by transfer of chromosome 8p region) vs parental MDA-MB-231 cells (deleted chromosome 8p)."} {"geneset":"YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN","description":"Genes down-regulated in HUVEC cells (endothelium) by ETS1 [GeneID=2113] which were up-regulated by SP100 [GeneID=6672]."} {"geneset":"YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_UP","description":"Genes up-regulated in HUVEC cells (endothelium) by ETS1 [GeneID=2113] which were down-regulated by SP100 [GeneID=6672]."} {"geneset":"KANG_GIST_WITH_PDGFRA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_GIST_WITH_PDGFRA_UP","description":"Genes up-regulated in gastrointestinal stromal tumors (GIST) with PDGFRA [GeneID=5156] mutations."} {"geneset":"KANG_GIST_WITH_PDGFRA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_GIST_WITH_PDGFRA_DN","description":"Genes down-regulated in gastrointestinal stromal tumors (GIST) with PDGFRA [GeneID=5156] mutations."} {"geneset":"MEINHOLD_OVARIAN_CANCER_LOW_GRADE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEINHOLD_OVARIAN_CANCER_LOW_GRADE_UP","description":"Genes up-regulated in low grade (LMP and G1) serous ovarian carcinomas vs the higher grade invasive tumors (G2 and G3)."} {"geneset":"MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN","description":"Genes down-regulated in low grade (LMP and G1) serous ovarian carcinomas vs the higher grade invasive tumors (G2 and G3)."} {"geneset":"DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP","description":"Genes up-regulated in fibroblasts expressing different mutant forms of ERCC3 [GeneID=2071]: XP/CS (xeroderma pigmentosum (XP) and Cockraine's syndrome (CS)) vs TTD (trichothiodystrophy)."} {"geneset":"DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN","description":"Genes down-regulated in fibroblasts expressing different mutant forms of ERCC3 [GeneID=2071]: XP/CS (xeroderma pigmentosum (XP) and Cockraine's syndrome (CS)) vs TTD (trichothiodystrophy)."} {"geneset":"DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_UP","description":"Genes up-regulated in fibroblasts expressing the XP/CS mutant form of ERCC3 [GeneID=2071], after low dose UVC irradiation."} {"geneset":"DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_DN","description":"Genes down-regulated in fibroblasts expressing the XP/CS mutant form of ERCC3 [GeneID=2071], after low dose UVC irradiation."} {"geneset":"DACOSTA_UV_RESPONSE_VIA_ERCC3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_UV_RESPONSE_VIA_ERCC3_UP","description":"Genes up-regulated in fibroblasts expressing mutant forms of ERCC3 [GeneID=2071] after UV irradiation."} {"geneset":"DACOSTA_UV_RESPONSE_VIA_ERCC3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_UV_RESPONSE_VIA_ERCC3_DN","description":"Genes down-regulated in fibroblasts expressing mutant forms of ERCC3 [GeneID=2071] after UV irradiation."} {"geneset":"DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN","description":"Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [GeneID=2071], after UVC irradiation."} {"geneset":"DIRMEIER_LMP1_RESPONSE_LATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DIRMEIER_LMP1_RESPONSE_LATE_UP","description":"Cluster 3: genes up-regulated in B2264-19/3 cells (primary B lymphocytes) within 60-180 min after activation of LMP1 (an oncogene encoded by Epstein-Barr virus, EBV)."} {"geneset":"DIRMEIER_LMP1_RESPONSE_LATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DIRMEIER_LMP1_RESPONSE_LATE_DN","description":"Cluster 4: genes down-regulated in B2264-19/3 cells (primary B lymphocytes) within 60-180 min after activation of LMP1 (an oncogene encoded by Epstein-Barr virus, EBV)."} {"geneset":"HEIDENBLAD_AMPLICON_8Q24_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEIDENBLAD_AMPLICON_8Q24_UP","description":"Up-regulated genes whose expression is associated with amplification of the 8q24 chromosome region in pancreatic cancer cell lines."} {"geneset":"HEIDENBLAD_AMPLICON_8Q24_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEIDENBLAD_AMPLICON_8Q24_DN","description":"Down-regulated genes whose expression is associated with amplification of the 8q24 chromosome region in pancreatic cancer cell lines."} {"geneset":"HEIDENBLAD_AMPLICON_12P11_12_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEIDENBLAD_AMPLICON_12P11_12_UP","description":"Up-regulated genes whose expression is associated with amplification of the 12p11-12 chromosome in pancreatic cancer cell lines."} {"geneset":"HEIDENBLAD_AMPLICON_12P11_12_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEIDENBLAD_AMPLICON_12P11_12_DN","description":"Down-regulated genes whose expression is associated with amplification of the 12p11-12 chromosome in pancreatic cancer cell lines."} {"geneset":"AMUNDSON_GENOTOXIC_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMUNDSON_GENOTOXIC_SIGNATURE","description":"Genes discriminating genotoxic (DNA damaging) agents from other kinds of stresses."} {"geneset":"AMUNDSON_RESPONSE_TO_ARSENITE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMUNDSON_RESPONSE_TO_ARSENITE","description":"Genes discriminating responses to sodium arsenite [PubChem=26435] from other stresses."} {"geneset":"FUNG_IL2_SIGNALING_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUNG_IL2_SIGNALING_2","description":"Genes up-regulated by IL2 [GeneID=3558] in T1 cells (primary thymocytes immortalized by Tax, an HTLV-1 encoded gene)."} {"geneset":"FUNG_IL2_SIGNALING_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUNG_IL2_SIGNALING_1","description":"Genes up-regulated by IL2 [GeneID=3558] in both primary thymocytes and T1 cells (primary thymocytes immortalized by Tax, an HTLV-1 encoded gene)."} {"geneset":"FUNG_IL2_TARGETS_WITH_STAT5_BINDING_SITES_T1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUNG_IL2_TARGETS_WITH_STAT5_BINDING_SITES_T1","description":"Genes with putative STAT5 [GeneID=6777] binding sites; up-regulated by IL2 [GeneID=3558] only in T1 cells (primary thymocytes immortalized by Tax, an HTLV-1 encoded gene)."} {"geneset":"FUNG_IL2_TARGETS_WITH_STAT5_BINDING_SITES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUNG_IL2_TARGETS_WITH_STAT5_BINDING_SITES","description":"Genes with putative STAT5 [GeneID=6777] binding sites; up-regulated by IL2 [Gene D=3558] in both primary thymocytes and T1 cells (primary thymocytes immortalized by Tax, an HTLV-1 encoded gene)."} {"geneset":"SASAKI_TARGETS_OF_TP73_AND_TP63","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASAKI_TARGETS_OF_TP73_AND_TP63","description":"Genes up-regulated in DLD1 cells (colon cancer) by p73 beta [GeneID=7161] or by and p63 gamma [GeneID=8626] but not by p53 [GeneID=7157]."} {"geneset":"YANAGIHARA_ESX1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANAGIHARA_ESX1_TARGETS","description":"Genes down-regulated in U2-OS Tet-On cells (osteosarcoma) after induction of ESX1 [GeneID=80712] expression."} {"geneset":"WEINMANN_ADAPTATION_TO_HYPOXIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEINMANN_ADAPTATION_TO_HYPOXIA_UP","description":"Genes most up-regulated in hypoxia tolerant NCI H460 cells (lung cancer)."} {"geneset":"WEINMANN_ADAPTATION_TO_HYPOXIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEINMANN_ADAPTATION_TO_HYPOXIA_DN","description":"Genes most down-regulated in hypoxia tolerant NCI H460 cells (lung cancer)."} {"geneset":"TSUNODA_CISPLATIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSUNODA_CISPLATIN_RESISTANCE_UP","description":"Genes up-regulated in bladder cancer cells resistant to cisplatin [PubChem=2767] compared to the parental cells sensitive to the drug."} {"geneset":"TSUNODA_CISPLATIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSUNODA_CISPLATIN_RESISTANCE_DN","description":"Genes down-regulated in bladder cancer cells resistant to cisplatin [PubChem=2767] compared to the parental cells sensitive to the drug."} {"geneset":"MAINA_HYPOXIA_VHL_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAINA_HYPOXIA_VHL_TARGETS_UP","description":"Genes up-regulated by hypoxia in RCC4 cells (renal cell carcinoma) engineered to stably express VHL [GeneID=7428] off a plasmid vector."} {"geneset":"MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP","description":"Genes up-regulated in apoptotic tissues (neuroepithelium) after MDM4 [GeneID=4194] knockout."} {"geneset":"MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN","description":"Genes down-regulated in apoptotic tissues (neuroepithelium) after MDM4 [GeneID=4194] knockout."} {"geneset":"MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP","description":"Genes up-regulated in non-apoptotic tissues (fetal liver) after MDM4 [GeneID=4194] knockout."} {"geneset":"MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN","description":"Genes down-regulated in non-apoptotic tissues (fetal liver) after MDM4 [GeneID=4194] knockout."} {"geneset":"LI_WILMS_TUMOR_ANAPLASTIC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_WILMS_TUMOR_ANAPLASTIC_UP","description":"Selected up-regulated genes distinguishing between Wilms tumors of different histological types: anaplastic vs favorable histology."} {"geneset":"LI_WILMS_TUMOR_ANAPLASTIC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_WILMS_TUMOR_ANAPLASTIC_DN","description":"Selected down-regulated genes distinguishing between Wilms tumors of different histological types: anaplastic vs favorable histology."} {"geneset":"BORLAK_LIVER_CANCER_EGF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BORLAK_LIVER_CANCER_EGF_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) developed by transgenic mice overexpressing a secretable form of EGF [GeneID=1950] in liver."} {"geneset":"MANN_RESPONSE_TO_AMIFOSTINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MANN_RESPONSE_TO_AMIFOSTINE_UP","description":"Genes up-regulated in HCT116 cells (colon cancer) after treatment with amifostine [PubChem=2141] depending on the presence of TP53 [GeneID=7157]: TP53-positive vs TP53-null cells."} {"geneset":"MANN_RESPONSE_TO_AMIFOSTINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MANN_RESPONSE_TO_AMIFOSTINE_DN","description":"Genes down-regulated in HCT116 cells (colon cancer) after treatment with amifostine [PubChem=2141] depending on the presence of TP53 [GeneID=7157]: TP53-positive vs TP53-null cells."} {"geneset":"YAN_ESCAPE_FROM_ANOIKIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAN_ESCAPE_FROM_ANOIKIS","description":"Genes up-regulated in IEC-18 cells (intestinal epithelial cells) which avoided anoikis (a form of apoptosis) after detachment."} {"geneset":"DARWICHE_PAPILLOMA_RISK_HIGH_VS_LOW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_PAPILLOMA_RISK_HIGH_VS_LOW_UP","description":"Genes that classify skin lesions into high risk papilloma."} {"geneset":"DARWICHE_PAPILLOMA_RISK_HIGH_VS_LOW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DARWICHE_PAPILLOMA_RISK_HIGH_VS_LOW_DN","description":"Genes that classify skin lesions into low risk papilloma."} {"geneset":"OXFORD_RALA_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OXFORD_RALA_TARGETS_UP","description":"Genes up-regulated in the UMUC-3 cells (bladder cancer) after knockdown of RALA [GeneID=5898] by RNAi."} {"geneset":"OXFORD_RALA_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OXFORD_RALA_TARGETS_DN","description":"Genes down-regulated in the UMUC-3 cells (bladder cancer) after knockdown of RALA [GeneID=5898] by RNAi."} {"geneset":"OXFORD_RALB_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OXFORD_RALB_TARGETS_DN","description":"Genes down-regulated in the UMUC-3 cells (bladder cancer) after knockdown of RALB [GeneID=5899] by RNAi."} {"geneset":"OXFORD_RALB_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OXFORD_RALB_TARGETS_UP","description":"Genes up-regulated in the UMUC-3 cells (bladder cancer) after knockdown of RALB [GeneID=5899] by RNAi."} {"geneset":"OXFORD_RALA_AND_RALB_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OXFORD_RALA_AND_RALB_TARGETS_UP","description":"Genes up-regulated in the UMUC-3 cells (bladder cancer) after knockdown of both RALA and RALB [GeneID=5898;5899] by RNAi."} {"geneset":"OXFORD_RALA_AND_RALB_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OXFORD_RALA_AND_RALB_TARGETS_DN","description":"Genes down-regulated in the UMUC-3 cells (bladder cancer) after knockdown of both RALA and RALB [GeneID=5898;5899] by RNAi."} {"geneset":"OXFORD_RALA_OR_RALB_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OXFORD_RALA_OR_RALB_TARGETS_UP","description":"Genes up-regulated after knockdown of RALA or RALB [GeneiD=5898;5899], which were also differentially expressed in bladder cancer compared to normal bladder urothelium tissue."} {"geneset":"OXFORD_RALA_OR_RALB_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OXFORD_RALA_OR_RALB_TARGETS_DN","description":"Genes down-regulated after knockdown of RALA or RALB [GeneiD=5898;5899], which were also differentially expressed in bladder cancer compared to normal bladder urothelium tissue."} {"geneset":"LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP","description":"Genes up-regulated between two breast carcinoma subtypes: metaplastic (MCB) and ductal (DCB)."} {"geneset":"LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN","description":"Genes down-regulated between two breast carcinoma subtypes: metaplastic (MCB) and ductal (DCB)."} {"geneset":"WOOD_EBV_EBNA1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WOOD_EBV_EBNA1_TARGETS_UP","description":"Genes up-regulated in the Ad/AH cells (adenocarcinoma) engineered to stably express the Epstein-Barr virus (EBV) gene EBNA1."} {"geneset":"WOOD_EBV_EBNA1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WOOD_EBV_EBNA1_TARGETS_DN","description":"Genes down-regulated in the Ad/AH cells (adenocarcinoma) engineered to stably express the Epstein-Barr virus (EBV) gene EBNA1."} {"geneset":"MOHANKUMAR_HOXA1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOHANKUMAR_HOXA1_TARGETS_UP","description":"Up-regulated in MCF7 cells (breast cancer) by HOXA1 [GeneID=3198]."} {"geneset":"MOHANKUMAR_HOXA1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOHANKUMAR_HOXA1_TARGETS_DN","description":"Down-regulated in MCF7 cells (breast cancer) by HOXA1 [GeneID=3198]."} {"geneset":"DAIRKEE_TERT_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAIRKEE_TERT_TARGETS_UP","description":"Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [GeneID=7015] off a retroviral vector."} {"geneset":"DAIRKEE_TERT_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAIRKEE_TERT_TARGETS_DN","description":"Genes down-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [GeneID=7015] off a retroviral vector."} {"geneset":"DAWSON_METHYLATED_IN_LYMPHOMA_TCL1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAWSON_METHYLATED_IN_LYMPHOMA_TCL1","description":"Genes hypermethylated in at least one of the lymphoma tumors of transgenic mice overexpressing TCL1 [GeneID=8115] in germinal center B lymphocytes."} {"geneset":"MURATA_VIRULENCE_OF_H_PILORI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MURATA_VIRULENCE_OF_H_PILORI","description":"Selected genes up-regulated in WT-A10 cells (gastric epithelium) expressing the H. pilori virulence gene CagA."} {"geneset":"WANG_HCP_PROSTATE_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_HCP_PROSTATE_CANCER","description":"Genes with the high-CpG-density promoters (HCP) that were up-regulated in 1542-CP3TX cells (prostate cancer) compared to 1542-NPTX (normal prostate)."} {"geneset":"JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_UP","description":"Genes up-regulated in early vs late brain tumors induced by retroviral delivery of PDGFB [GeneID=5155]."} {"geneset":"JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN","description":"Genes down-regulated in early vs late brain tumors induced by retroviral delivery of PDGFB [GeneID=5155]."} {"geneset":"WIEMANN_TELOMERE_SHORTENING_AND_CHRONIC_LIVER_DAMAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIEMANN_TELOMERE_SHORTENING_AND_CHRONIC_LIVER_DAMAGE_UP","description":"Genes up-regulated by telomere shortening due to the knockout of TERC [GeneID=7012] in the presence of chronic liver damage."} {"geneset":"WIEMANN_TELOMERE_SHORTENING_AND_CHRONIC_LIVER_DAMAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIEMANN_TELOMERE_SHORTENING_AND_CHRONIC_LIVER_DAMAGE_DN","description":"Genes down-regulated by telomere shortening due to the knockout of TERC [GeneID=7012] in the presence of chronic liver damage."} {"geneset":"MAINA_VHL_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAINA_VHL_TARGETS_UP","description":"Genes up-regulated in RCC4 cells (renal cell carcinoma) engineered to stably express VHL [GeneID=7428] off a plasmid vector."} {"geneset":"MAINA_VHL_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAINA_VHL_TARGETS_DN","description":"Genes down-regulated in RCC4 cells (renal cell carcinoma) engineered to stably express VHL [GeneID=7428] off a plasmid vector."} {"geneset":"GRUETZMANN_PANCREATIC_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRUETZMANN_PANCREATIC_CANCER_UP","description":"Genes up-regulated in pancreatic ductal adenocarcinoma (PDAC) identified in a meta analysis across four independent studies."} {"geneset":"GRUETZMANN_PANCREATIC_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRUETZMANN_PANCREATIC_CANCER_DN","description":"Genes down-regulated in pancreatic ductal adenocarcinoma (PDAC) identified in a meta analysis across four independent studies."} {"geneset":"JAZAG_TGFB1_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAZAG_TGFB1_SIGNALING_UP","description":"Genes up-regulated in PANC-1-puro cells (pancreatic cancer) stimulated by TGF1B [GeneID=7040] for 2 h."} {"geneset":"JAZAG_TGFB1_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAZAG_TGFB1_SIGNALING_DN","description":"Genes down-regulated in PANC-1-puro cells (pancreatic cancer) stimulated by TGF1B [GeneID=7040] for 2 h."} {"geneset":"JAZAG_TGFB1_SIGNALING_VIA_SMAD4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAZAG_TGFB1_SIGNALING_VIA_SMAD4_UP","description":"Genes up-regulated in PANC-1-S4KD cells (pancreatic cancer; SMAD4 [GeneID=4089] knocked down by RNAi) after stimulation by TGF1B [GeneID=7040] for 2 h."} {"geneset":"JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN","description":"Genes down-regulated in PANC-1-S4KD cells (pancreatic cancer; SMAD4 [GeneID=4089] knocked down by RNAi) after stimulation by TGF1B [GeneID=7040] for 2 h."} {"geneset":"LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_UP","description":"Genes up-regulated in Wilm's tumor vs fetal kidney."} {"geneset":"LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN","description":"Genes down-regulated in Wilm's tumor vs fetal kidney."} {"geneset":"SIMBULAN_UV_RESPONSE_NORMAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIMBULAN_UV_RESPONSE_NORMAL_UP","description":"Genes up-regulated in HFK cells (primary keratinocytes) in response to UVB irradiation."} {"geneset":"SIMBULAN_UV_RESPONSE_NORMAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIMBULAN_UV_RESPONSE_NORMAL_DN","description":"Genes down-regulated in HFK cells (primary keratinocytes) in response to UVB irradiation."} {"geneset":"SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN","description":"Genes down-regulated in response to UVB radiation in HFK cells (keratinocytes) immortalized by overexpression of HPV E6 and E7 viral oncogenes."} {"geneset":"CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP","description":"Genes up-regulated in K562 cells (chronic myelogenous leukemia, CML) expressing TP53 and MYC [GeneID=7157;4609]."} {"geneset":"CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN","description":"Genes down-regulated in K562 cells (chronic myelogenous leukemia, CML) expressing TP53 and MYC [GeneID=7157;4609]."} {"geneset":"INAMURA_LUNG_CANCER_SCC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/INAMURA_LUNG_CANCER_SCC_UP","description":"Up-regulated genes characteristic to the squamous cell carcinoma (SCC) type of non-small cell lung cancer (NSCLC)."} {"geneset":"INAMURA_LUNG_CANCER_SCC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/INAMURA_LUNG_CANCER_SCC_DN","description":"Down-regulated genes characteristic to the squamous cell carcinoma (SCC) type of non-small cell lung cancer (NSCLC)."} {"geneset":"INAMURA_LUNG_CANCER_SCC_SUBTYPES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/INAMURA_LUNG_CANCER_SCC_SUBTYPES_UP","description":"Up-regulated genes discriminating between two subtypes of squamous cell carcinoma (SCC) type of non-small cell lung cancer: SSC-A vs SSC-B."} {"geneset":"INAMURA_LUNG_CANCER_SCC_SUBTYPES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/INAMURA_LUNG_CANCER_SCC_SUBTYPES_DN","description":"Down-regulated genes discriminating between two subtypes of squamous cell carcinoma (SCC) type of non-small cell lung cancer: SSC-A vs SSC-B."} {"geneset":"WATTEL_AUTONOMOUS_THYROID_ADENOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WATTEL_AUTONOMOUS_THYROID_ADENOMA_UP","description":"Up-regulated genes characteristic for autonomous thyroid adenoma."} {"geneset":"WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN","description":"Down-regulated genes characteristic for autonomous thyroid adenoma."} {"geneset":"SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION","description":"Genes down-regulated in MEF and REF cells (mouse and rat fibroblasts) but not in TIG3/T cells (human lung fibroblasts expressing TERT [GeneID=7015]) by co-expression of the SV40 early region and the activated HRAS (H-RasV12) [GeneID=3265]."} {"geneset":"KIM_MYC_AMPLIFICATION_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_MYC_AMPLIFICATION_TARGETS_UP","description":"Genes positively correlated with amplifications of MYC [GeneID=4609] in SCLC (small cell lung cancer) cell lines."} {"geneset":"KIM_MYC_AMPLIFICATION_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_MYC_AMPLIFICATION_TARGETS_DN","description":"Genes negatively correlated with amplifications of MYC [GeneID=4609] in SCLC (small cell lung cancer) cell lines."} {"geneset":"KIM_MYCN_AMPLIFICATION_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_MYCN_AMPLIFICATION_TARGETS_UP","description":"Genes positively correlated with amplifications of MYCN [GeneID=4613] in the SCLC (small cell lung cancer) cell lines."} {"geneset":"KIM_MYCN_AMPLIFICATION_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_MYCN_AMPLIFICATION_TARGETS_DN","description":"Genes negatively correlated with amplifications of MYCN [GeneID=4613] in the SCLC (small cell lung cancer) cell lines."} {"geneset":"KIM_MYCL1_AMPLIFICATION_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_MYCL1_AMPLIFICATION_TARGETS_UP","description":"Genes positively correlated with amplifications of MYCL1 [GeneID=4610] in SCLC (small cell lung cancer) cell lines."} {"geneset":"KIM_MYCL1_AMPLIFICATION_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_MYCL1_AMPLIFICATION_TARGETS_DN","description":"Genes negatively correlated with amplifications of MYCL1 [GeneID=4610] in SCLC (small cell lung cancer) cell lines."} {"geneset":"TSAI_RESPONSE_TO_IONIZING_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSAI_RESPONSE_TO_IONIZING_RADIATION","description":"Genes up-regulated in TK6, WTK1, and NH32 cell lines (lymphoblast) in response to ionizing radiation."} {"geneset":"YANG_BREAST_CANCER_ESR1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_BREAST_CANCER_ESR1_UP","description":"Genes up-regulated in early primary breast tumors expressing ESR1 [GeneID=2099] vs the ESR1 negative ones."} {"geneset":"YANG_BREAST_CANCER_ESR1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_BREAST_CANCER_ESR1_DN","description":"Genes down-regulated in early primary breast tumors expressing ESR1 [GeneID=2099] vs the ESR1 negative ones."} {"geneset":"YANG_BREAST_CANCER_ESR1_LASER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_BREAST_CANCER_ESR1_LASER_UP","description":"Genes up-regulated in laser microdissected (LCM) samples of early primary breast tumors expressing ESR1 [GeneID=2099] vs the ESR1 negative ones."} {"geneset":"YANG_BREAST_CANCER_ESR1_LASER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_BREAST_CANCER_ESR1_LASER_DN","description":"Genes down-regulated in laser microdissected (LCM) samples of early primary breast tumors expressing ESR1 [GeneID=2099] vs the ESR1 negative ones."} {"geneset":"YANG_BREAST_CANCER_ESR1_BULK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_BREAST_CANCER_ESR1_BULK_UP","description":"Genes up-regulated in bulk samples from early primary breast tumors expressing ESR1 [GeneID=2099] vs the ESR1 negative samples."} {"geneset":"YANG_BREAST_CANCER_ESR1_BULK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_BREAST_CANCER_ESR1_BULK_DN","description":"Genes down-regulated in bulk samples from early primary breast tumors expressing ESR1 [GeneID=2099] vs the ESR1 negative samples."} {"geneset":"WANG_RESPONSE_TO_BEXAROTENE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_BEXAROTENE_UP","description":"Genes up-regulated in the mouse lung cancer model and which reverted to normal levels upon treatment with bexarotene [PubChem=82146]."} {"geneset":"WANG_RESPONSE_TO_BEXAROTENE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_BEXAROTENE_DN","description":"Genes down-regulated in the mouse lung cancer model and which reverted to normal levels upon treatment with bexarotene [PubChem=82146]."} {"geneset":"STANHILL_HRAS_TRANSFROMATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STANHILL_HRAS_TRANSFROMATION_UP","description":"Selected genes up-regulated in Rat1Ras cells (fibroblasts) which were transformed by expression of an oncogenic activated form of HRAS [GeneID=3265] compared to the parental Rat1 cells."} {"geneset":"REN_MIF_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REN_MIF_TARGETS_DN","description":"Genes down-regulated in SK-N-DZ cells (neuroblastoma) after knockdown of MIF [GeneID=4282] by antisense RNA."} {"geneset":"SEMBA_FHIT_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEMBA_FHIT_TARGETS_UP","description":"Genes up-regulated in H1299 cells (non-small cell lung cancer, NSCLC) expressing the Y144F mutant form of FHIT [GeneID=2272]."} {"geneset":"SEMBA_FHIT_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEMBA_FHIT_TARGETS_DN","description":"Genes down-regulated in H1299 cells (non-small cell lung cancer, NSCLC) expressing the Y144F mutant form of FHIT [GeneID=2272]."} {"geneset":"SHANK_TAL1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHANK_TAL1_TARGETS_DN","description":"Genes down-regulated in preleukemic thymocytes from transgenic mice which overexpress TAL1 [GeneID=6886] in thymus."} {"geneset":"HASINA_NOL7_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASINA_NOL7_TARGETS_UP","description":"Genes up-regulated in SiHa cells (cervical carcinoma) by stable expression of NOL7 [GeneID=51406] off a plasmid vector."} {"geneset":"HASINA_NOL7_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASINA_NOL7_TARGETS_DN","description":"Genes down-regulated in SiHa cells (cervical carcinoma) by stable expression of NOL7 [GeneID=51406] off a plasmid vector."} {"geneset":"KONDO_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KONDO_HYPOXIA","description":"Genes up-regulated in HSC-2/8 cells (chondrosarcoma) under hypoxic conditions."} {"geneset":"HOWLIN_PUBERTAL_MAMMARY_GLAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOWLIN_PUBERTAL_MAMMARY_GLAND","description":"Genes up-regulated in pubertal mammary glands compared to mammary glands from other developmental stages."} {"geneset":"KREPPEL_CD99_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KREPPEL_CD99_TARGETS_UP","description":"Genes up-regulated in ESFT cells (Ewing's sarcoma family of tumors) after knockdown of CD99 [GeneID=4267] by RNAi."} {"geneset":"KREPPEL_CD99_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KREPPEL_CD99_TARGETS_DN","description":"Genes down-regulated in ESFT cells (Ewing's sarcoma family of tumors) after knockdown of CD99 [GeneID=4267] by RNAi."} {"geneset":"HATADA_METHYLATED_IN_LUNG_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HATADA_METHYLATED_IN_LUNG_CANCER_UP","description":"Genes with hypermethylated DNA in lung cancer samples."} {"geneset":"HATADA_METHYLATED_IN_LUNG_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HATADA_METHYLATED_IN_LUNG_CANCER_DN","description":"Genes with unmethylated DNA in lung cancer samples."} {"geneset":"CALVET_IRINOTECAN_SENSITIVE_VS_RESISTANT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CALVET_IRINOTECAN_SENSITIVE_VS_RESISTANT_UP","description":"Genes up-regulated in neuroblastoma xenografts: sensitive vs resistant to the topoisomerase inhibitor irinotecan [GeneID=3750]."} {"geneset":"CALVET_IRINOTECAN_SENSITIVE_VS_RESISTANT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CALVET_IRINOTECAN_SENSITIVE_VS_RESISTANT_DN","description":"Genes down-regulated in neuroblastoma xenografts: sensitive vs resistant to the topoisomerase inhibitor irinotecan [GeneID=3750]."} {"geneset":"CALVET_IRINOTECAN_SENSITIVE_VS_REVERTED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CALVET_IRINOTECAN_SENSITIVE_VS_REVERTED_UP","description":"Genes up-regulated in neuroblastoma xenografts: resistant vs those that reverted to be sensitive to the topoisomerase inhibitor irinotecan [PubChem=3750]."} {"geneset":"CALVET_IRINOTECAN_SENSITIVE_VS_REVERTED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CALVET_IRINOTECAN_SENSITIVE_VS_REVERTED_DN","description":"Genes down-regulated in neuroblastoma xenografts: resistant vs those that reverted to be sensitive to the topoisomerase inhibitor irinotecan [PubChem=3750]."} {"geneset":"FURUKAWA_DUSP6_TARGETS_PCI35_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FURUKAWA_DUSP6_TARGETS_PCI35_UP","description":"Genes up-regulated in PCI-35 cells (pancreatic cancer, lack endogenous DUSP6 [GeneID=1848]) upon expression of DUSP6 off an adenoviral vector."} {"geneset":"FURUKAWA_DUSP6_TARGETS_PCI35_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FURUKAWA_DUSP6_TARGETS_PCI35_DN","description":"Genes down-regulated in PCI-35 cells (pancreatic cancer, lack endogenous DUSP6 [GeneID=1848]) upon expression of DUSP6 off an adenoviral vector."} {"geneset":"WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_UP","description":"Genes specifically up-regulated via JNK (MAPK8) [GeneID=5599] signaling pathway activated by paclitaxel [PubChem=4666] in BR cells (ovarian cancer)."} {"geneset":"WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_DN","description":"Genes specifically down-regulated via JNK (MAPK8) [GeneID=5599] signaling pathway activated by paclitaxel [PubChem=4666] in BR cells (ovarian cancer)."} {"geneset":"KARAKAS_TGFB1_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KARAKAS_TGFB1_SIGNALING","description":"Genes up-regulated by TGFB1 [GeneID=7040] in MCF10A cells (breast cancer): both wild-type and those lacking p21 [GeneID=1026]."} {"geneset":"SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1","description":"Cluster PAM1: genes up-regulated in hepatocellular carcinoma (HCC) vs normal liver tissue from mice deficient for TXNIP [GeneID=10628]."} {"geneset":"SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2","description":"Cluster PAM2: genes up-regulated in hepatocellular carcinoma (HCC) vs normal liver tissue from mice deficient for TXNIP [GeneID=10628]."} {"geneset":"SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3","description":"Cluster PAM3: genes most highly up-regulated in hepatocellular carcinoma (HCC) vs normal liver tissue from mice deficient for TXNIP [GeneID=10628]."} {"geneset":"SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4","description":"Cluster PAM4: genes down-regulated in hepatocellular carcinoma (HCC) vs normal liver tissue from mice deficient for TXNIP [GeneID=10628]."} {"geneset":"SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM5","description":"Cluster PAM5: genes changed exclusively in hepatocellular carcinoma (HCC) samples from 27 month old mice deficient for TXNIP [GeneID=10628]."} {"geneset":"SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM6","description":"Cluster PAM6: genes changed exclusively in normal liver tissue adjacent to hepatocellular carcinoma (HCC) from mice deficient for TXNIP [GeneID=10628]."} {"geneset":"LIEN_BREAST_CARCINOMA_METAPLASTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIEN_BREAST_CARCINOMA_METAPLASTIC","description":"Genes up-regulated in metaplastic carcinoma of the breast (MCB) subclass 2 compared to the MCB subclass 1."} {"geneset":"SCHMAHL_PDGF_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHMAHL_PDGF_SIGNALING","description":"These genes form a a network that controls specific processes downstream of PDGF signaling."} {"geneset":"TOMLINS_PROSTATE_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOMLINS_PROSTATE_CANCER_UP","description":"Genes up-regulated in prostate cancer vs benign prostate tissue, based on a meta-analysis of five gene expression profiling studies."} {"geneset":"TOMLINS_PROSTATE_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOMLINS_PROSTATE_CANCER_DN","description":"Genes down-regulated in prostate cancer vs benign prostate tissue, based on a meta-analysis of five gene expression profiling studies."} {"geneset":"TOMLINS_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOMLINS_METASTASIS_UP","description":"Top genes up-regulated in hormone refractory metastatic prostate cancer compared to localized prostate cancer."} {"geneset":"TOMLINS_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOMLINS_METASTASIS_DN","description":"Top genes down-regulated in hormone refractory metastatic prostate cancer compared to localized prostate cancer."} {"geneset":"LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP","description":"Genes up-regulated in LSK cells (bone marrow) as a function of a QTL for the size of hematopoietic stem cell (HSC) population: comparison of congenic B.D. chr3 (BD, large HSC size) vs parental B6 strain (tiny HSC size)."} {"geneset":"LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_DN","description":"Genes down-regulated in LSK cells (bone marrow) as a function of a QTL for the size of hematopoietic stem cell (HSC) population: comparison of congenic B.D. chr3 (BD, large HSC size) vs parental B6 strain (tiny HSC size)."} {"geneset":"LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP","description":"Genes up-regulated in LSK cells (bone marrow) as a function of a QTL for the size of hematopoietic stem cell (HSC) population: comparison of congenic D.B. Chr 3 (DB, small HSC population) vs parental D2 strain (huge HSC population)."} {"geneset":"LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN","description":"Genes down-regulated in LSK cells (bone marrow) as a function of a QTL for the size of hematopoietic stem cell (HSC) population: comparison of congenic D.B. Chr 3 (DB, small HSC population) vs parental D2 strain (huge HSC population)."} {"geneset":"SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_UP","description":"Genes up-regulated more than two-fold in lymphoblastoid cell lines from European population compared to those from Asian population."} {"geneset":"SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_DN","description":"Genes down-regulated more than two-fold in lymphoblastoid cell lines from European population compared to those from Asian population."} {"geneset":"SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP","description":"Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population."} {"geneset":"SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN","description":"Genes down-regulated in lymphoblastoid cells from the European population compared to those from the Asian population."} {"geneset":"HUI_MAPK14_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUI_MAPK14_TARGETS_UP","description":"Genes up-regulated in fetal liver (days E13.5 and E15.5) samples from embryo-specific Cre-lox knockout of MAPK14 [GeneID=1432]."} {"geneset":"DIERICK_SEROTONIN_FUNCTION_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DIERICK_SEROTONIN_FUNCTION_GENES","description":"Genes involved in serotonin [PubChem=5202] function, orthologs computed from D. melanogaster genes using InsParanoid resource."} {"geneset":"THEODOROU_MAMMARY_TUMORIGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THEODOROU_MAMMARY_TUMORIGENESIS","description":"Candidate mammary tumorigenesis genes from the common insertion sites (CIS) of MMTV virus that induced breast tumors in mice."} {"geneset":"BALLIF_DEVELOPMENTAL_DISABILITY_P16_P12_DELETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BALLIF_DEVELOPMENTAL_DISABILITY_P16_P12_DELETION","description":"Candidate genes in the pericentromeric microdeletion in 16p11.2-p12.2 associated with developmental disabilities."} {"geneset":"SCHLESINGER_METHYLATED_IN_COLON_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLESINGER_METHYLATED_IN_COLON_CANCER","description":"Genes expressed in normal colon; they undergo down-regulation in tumors through DNA methylation."} {"geneset":"JIANG_CORE_DUPLICON_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_CORE_DUPLICON_GENES","description":"Genes mapped to core duplicons - elements shared by a majority of segmental duplication blocks."} {"geneset":"PUJANA_BREAST_CANCER_LIT_INT_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_BREAST_CANCER_LIT_INT_NETWORK","description":"Genes constituting the LIT-Int network of proteins interacting with breast cancer reference proteins BRCA1, BRCA2, ATM, and CHEK2 [GeneID=672;675;472;11200]; the interactions were manually curated from the literature."} {"geneset":"PUJANA_XPRSS_INT_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_XPRSS_INT_NETWORK","description":"Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1, BRCA2, ATM, and CHEK2 [GeneID=672;675;472;11200] in a compendium of normal tissues."} {"geneset":"PUJANA_BRCA1_PCC_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_BRCA1_PCC_NETWORK","description":"Genes constituting the BRCA1-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient, PCC >= 0.4) with that of BRCA1 [GeneID=672] across a compendium of normal tissues."} {"geneset":"PUJANA_BRCA2_PCC_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_BRCA2_PCC_NETWORK","description":"Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient, PCC >= 0.4) with that of BRCA2 [GeneID=675] across a compendium of normal tissues."} {"geneset":"PUJANA_ATM_PCC_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_ATM_PCC_NETWORK","description":"Genes constituting the ATM-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient, PCC >= 0.4) with that of ATM [GeneID=472] across a compendium of normal tissues."} {"geneset":"PUJANA_CHEK2_PCC_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_CHEK2_PCC_NETWORK","description":"Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient, PCC >= 0.4) with that of CHEK2 [GeneID=11200]."} {"geneset":"PUJANA_BRCA_CENTERED_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_BRCA_CENTERED_NETWORK","description":"Genes constituting the BRCA-centered network (BCN)."} {"geneset":"SCHLESINGER_H3K27ME3_IN_NORMAL_AND_METHYLATED_IN_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLESINGER_H3K27ME3_IN_NORMAL_AND_METHYLATED_IN_CANCER","description":"Genes bearing the H3K27me3 mark in normal cells; their DNA is methylated in cancer cells."} {"geneset":"SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER","description":"Genes bearing H3K27me3 mark or whose promoters are bound by the polycomb proteins SUZ12 or EED [GeneID=23512;8726]; their DNA is methylated de novo in cancer."} {"geneset":"GOERING_BLOOD_HDL_CHOLESTEROL_QTL_CIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOERING_BLOOD_HDL_CHOLESTEROL_QTL_CIS","description":"Top scoring cis-regulated QTL (quantitative trait loci) influencing blood levels of high-density lipoprotein (HDL) cholesterol."} {"geneset":"GOERING_BLOOD_HDL_CHOLESTEROL_QTL_TRANS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOERING_BLOOD_HDL_CHOLESTEROL_QTL_TRANS","description":"Top scoring trans-regulated expression quantitative trait loci (eQTL) influencing blood levels of high-density lipoprotein (HDL) cholesterol."} {"geneset":"KHETCHOUMIAN_TRIM24_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KHETCHOUMIAN_TRIM24_TARGETS_UP","description":"Retinoic acid-responsive genes up-regulated in hepatocellular carcinoma (HCC) samples of TRIM24 [GeneID=8805] knockout mice."} {"geneset":"KHETCHOUMIAN_TRIM24_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KHETCHOUMIAN_TRIM24_TARGETS_DN","description":"Retinoic acid-responsive genes down-regulated in hepatocellular carcinoma (HCC) samples of TRIM24 [GeneID=8805] knockout mice."} {"geneset":"OHM_METHYLATED_IN_ADULT_CANCERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OHM_METHYLATED_IN_ADULT_CANCERS","description":"Genes showing frequent DNA methylation and which are silenced in adult cancers but remain unmethylated in embryonic carcinoma and embryonic stem (ES) cells."} {"geneset":"OHM_EMBRYONIC_CARCINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OHM_EMBRYONIC_CARCINOMA_UP","description":"Genes with a high basal transcription state in undifferentiated embryonic carcinoma cells."} {"geneset":"OHM_EMBRYONIC_CARCINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OHM_EMBRYONIC_CARCINOMA_DN","description":"Genes with low to medium basal transcription state in undifferentiated embryonic carcinoma cells."} {"geneset":"ALCALA_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALCALA_APOPTOSIS","description":"Genes able to induce cell death in an expression cDNA library screen."} {"geneset":"OKAWA_NEUROBLASTOMA_1P36_31_DELETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OKAWA_NEUROBLASTOMA_1P36_31_DELETION","description":"Genes in the smallest region of deletion (SRD) in 1p36.3 area in neuroblastoma samples."} {"geneset":"COWLING_MYCN_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COWLING_MYCN_TARGETS","description":"Genes down-regulated by MYCN [GeneID=4613] but not by its transactivation-defficient, trunkated form N-Myc-delta-73."} {"geneset":"GROSS_HYPOXIA_VIA_HIF1A_ONLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_HIF1A_ONLY","description":"Genes uniquely up-regulated in SEND cells (skin endothelium) at hypoxia after knockdown of HIF1A [GeneID=3091] by RNAi."} {"geneset":"FALVELLA_SMOKERS_WITH_LUNG_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FALVELLA_SMOKERS_WITH_LUNG_CANCER","description":"Genes that distinguish normal from cancer (lung adenocarcinoma) samples and smokers from non-smoking subjects."} {"geneset":"OZEN_MIR125B1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OZEN_MIR125B1_TARGETS","description":"Potential targets of MIR125B1 [GeneID=406911] microRNA which are up-regulated in prostate cancer."} {"geneset":"GALIE_TUMOR_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALIE_TUMOR_ANGIOGENESIS","description":"Angiogenic genes up-regulated in A17 carcinomas (high vascularization) compared to the syngeneic BB1 and spontaneous tumors (little vascularization)."} {"geneset":"GALIE_TUMOR_STEMNESS_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALIE_TUMOR_STEMNESS_GENES","description":"Stemness-related genes changed in A17 carcinomas (MTC, mesenchymal tumor cells) compared with the mesenchymal stem cells (MSC)."} {"geneset":"KAUFFMANN_MELANOMA_RELAPSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAUFFMANN_MELANOMA_RELAPSE_UP","description":"DNA repair and replication genes up-regulated in melanoma patients who will relapse vs patients who will not."} {"geneset":"KAUFFMANN_MELANOMA_RELAPSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAUFFMANN_MELANOMA_RELAPSE_DN","description":"DNA repair and replication genes down-regulated in melanoma patients who will relapse vs patients who will not."} {"geneset":"WILLIAMS_ESR1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILLIAMS_ESR1_TARGETS_UP","description":"The 'ER-alpha profile': genes up-regulated in T47D cells (breast cancer, ESR2 [GeneID=2100] Tet-Off) upon activation of ESR1 [GeneID=2099] by estradiol (E2) [PubChem=5757]."} {"geneset":"WILLIAMS_ESR1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILLIAMS_ESR1_TARGETS_DN","description":"The 'ER-alpha profile': genes down-regulated in T47D cells (breast cancer, ESR2 [GeneID=2100] Tet-Off) upon activation of ESR1 [GeneID=2099] by estradiol (E2) [PubChem=5757]."} {"geneset":"WILLIAMS_ESR2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILLIAMS_ESR2_TARGETS_UP","description":"Genes uniquely up-regulated in T47D cells (breast cancer) by induction of ESR2 [GeneID=2100] expression in the Tet-Off system."} {"geneset":"WILLIAMS_ESR2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILLIAMS_ESR2_TARGETS_DN","description":"Genes uniquely down-regulated in T47D cells (breast cancer) by induction of ESR2 [GeneID=2100] expression in the Tet-Off system."} {"geneset":"GROSS_ELK3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_ELK3_TARGETS_UP","description":"Genes up-regulated in SEND cells (skin endothelium) at normal oxygen (normoxia) conditions after knockdown of ELK3 [GeneID=2004] by RNAi."} {"geneset":"GROSS_ELK3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_ELK3_TARGETS_DN","description":"Genes down-regulated in SEND cells (skin endothelium) at normal oxygen (normoxia) conditions after knockdown of ELK3 [GeneID=2004] by RNAi."} {"geneset":"GROSS_HYPOXIA_VIA_ELK3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_ELK3_UP","description":"Genes up-regulated in SEND cells (skin endothelium) at hypoxia with ELK3 [GeneID=2004] knockdown by RNAi."} {"geneset":"GROSS_HYPOXIA_VIA_ELK3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_ELK3_DN","description":"Genes down-regulated in SEND cells (skin endothelium) at hypoxia with ELK3 [GeneID=2004] knockdown by RNAi."} {"geneset":"GROSS_HIF1A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HIF1A_TARGETS_UP","description":"Genes up-regulated in SEND cells (skin endothelium) at normal oxygen (normoxia) conditions after knockdown of HIF1A [GeneID=3091] by RNAi."} {"geneset":"GROSS_HIF1A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HIF1A_TARGETS_DN","description":"Genes down-regulated in SEND cells (skin endothelium) at normal oxygen (normoxia) conditions after knockdown of HIF1A [GeneID=3091] by RNAi."} {"geneset":"GROSS_HYPOXIA_VIA_HIF1A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_HIF1A_UP","description":"Genes up-regulated in SEND cells (skin endothelium) at hypoxia after knockdown of HIF1A [GeneID=3091] by RNAi."} {"geneset":"GROSS_HYPOXIA_VIA_HIF1A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_HIF1A_DN","description":"Genes down-regulated in SEND cells (skin endothelium) at hypoxia after knockdown of HIF1A [GeneID=3091] by RNAi."} {"geneset":"GROSS_HYPOXIA_VIA_ELK3_ONLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_ELK3_ONLY_UP","description":"Genes specifically up-regulated in SEND cells (skin endothelium) at hypoxia after knockdown of ELK3 [GeneID=2004] by RNAi."} {"geneset":"GROSS_HYPOXIA_VIA_ELK3_ONLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_ELK3_ONLY_DN","description":"Genes specifically down-regulated in SEND cells (skin endothelium) at hypoxia after knockdown of ELK3 [GeneID=2004] by RNAi."} {"geneset":"GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP","description":"Genes up-regulated in SEND cells (skin endothelium) at hypoxia after knockdown of ELK3 [GeneID=2004] and HIF1A [GeneID=3091] by RNAi."} {"geneset":"GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN","description":"Genes down-regulated in SEND cells (skin endothelium) at hypoxia after knockdown of ELK3 [GeneID=2004] and HIF1A [GeneID=3091] by RNAi."} {"geneset":"NUYTTEN_NIPP1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUYTTEN_NIPP1_TARGETS_UP","description":"Genes up-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [GeneID=5511] by RNAi."} {"geneset":"NUYTTEN_NIPP1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUYTTEN_NIPP1_TARGETS_DN","description":"Genes down-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [GeneID=5511] by RNAi."} {"geneset":"NUYTTEN_EZH2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUYTTEN_EZH2_TARGETS_UP","description":"Genes up-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [GeneID=2146] by RNAi."} {"geneset":"NUYTTEN_EZH2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUYTTEN_EZH2_TARGETS_DN","description":"Genes down-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [GeneID=2146] by RNAi."} {"geneset":"INGRAM_SHH_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/INGRAM_SHH_TARGETS_UP","description":"Genes up-regulated in 10T1/2 cells (multipotent mesoderma) by expression of SHH [GeneID=6469]."} {"geneset":"INGRAM_SHH_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/INGRAM_SHH_TARGETS_DN","description":"Genes down-regulated in 10T1/2 cells (multipotent mesoderma) by expression of SHH [GeneID=6469]."} {"geneset":"MANTOVANI_NFKB_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MANTOVANI_NFKB_TARGETS_UP","description":"NF-kB-controlled genes up-regulated in endothelial cells in response to viral GPCR protein."} {"geneset":"MANTOVANI_NFKB_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MANTOVANI_NFKB_TARGETS_DN","description":"NF-kB-controlled genes down-regulated in endothelial cells in response to viral GPCR protein."} {"geneset":"MANTOVANI_VIRAL_GPCR_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MANTOVANI_VIRAL_GPCR_SIGNALING_UP","description":"Up-regulated genes in the expression signature of direct and paracrine viral GPCR signaling in endothelial cells."} {"geneset":"MANTOVANI_VIRAL_GPCR_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MANTOVANI_VIRAL_GPCR_SIGNALING_DN","description":"Down-regulated genes in the expression signature of direct and paracrine viral GPCR signaling in endothelial cells."} {"geneset":"BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP","description":"Genes up-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress."} {"geneset":"BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN","description":"Genes down-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress."} {"geneset":"FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP","description":"Genes up-regulated in genomically unstable Ewing's sarcoma tumors compared to the stable ones."} {"geneset":"FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_DN","description":"Genes down-regulated in genomically unstable Ewing's sarcoma tumors compared to the stable ones."} {"geneset":"NAKAYAMA_FRA2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAYAMA_FRA2_TARGETS","description":"Genes down-regulated in ST1 cells (adult T-cell leukemia, ATL) after knockdown of FRA2 [GeneID=2355] by RNAi."} {"geneset":"LOPEZ_MBD_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MBD_TARGETS","description":"Genes up-regulated in HeLa cells (cervical cancer) after simultaneus knockdown of all three MBD (methyl-CpG binding domain) proteins MeCP2, MBD1 and MBD2 [GeneID=4204;4152;8932] by RNAi."} {"geneset":"LOPEZ_MBD_TARGETS_IMPRINTED_AND_X_LINKED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MBD_TARGETS_IMPRINTED_AND_X_LINKED","description":"X chromosome and imprinted genes up-regulated in HeLa cells (cervical cancer) after knockdown of the MBD (methyl-CpG binding domain) proteins by RNAi."} {"geneset":"ROPERO_HDAC2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROPERO_HDAC2_TARGETS","description":"Genes up-regulated genes in cell lines with HDAC2 [GeneID=3066] loss of function (LOS)."} {"geneset":"GOUYER_TUMOR_INVASIVENESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOUYER_TUMOR_INVASIVENESS","description":"Genes up-regulated in constitutively invasive HT-29 5M21 cells (colon cancer) vs the parental non-invasive cells."} {"geneset":"LIU_LIVER_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_LIVER_CANCER","description":"Low abundance transcripts specific to hepatocellular carcinoma (HCC)."} {"geneset":"LIU_BREAST_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_BREAST_CANCER","description":"Low abundance transcripts specific for breast cancer."} {"geneset":"LIU_NASOPHARYNGEAL_CARCINOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_NASOPHARYNGEAL_CARCINOMA","description":"Low abundance transcripts specific to nasopharyngeal carcinoma (NPC)."} {"geneset":"LIU_COMMON_CANCER_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_COMMON_CANCER_GENES","description":"Low abundance transcripts common to nasopharyngeal carcinoma (NPC), breast and liver tumors."} {"geneset":"LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER","description":"Overexpressed genes with amplified copy number across 27 non-small cell lung cancer (NSCLC) cell lines."} {"geneset":"FREDERICK_PRKCI_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FREDERICK_PRKCI_TARGETS","description":"Genes down-regulated in H1703 cells (non-small cell lung cancer, NSCLC) after knockdown of PRKCI [GeneID=5584] by RNAi."} {"geneset":"RAHMAN_TP53_TARGETS_PHOSPHORYLATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAHMAN_TP53_TARGETS_PHOSPHORYLATED","description":"Proteins phosporylated in HCT116 cells (colon cancer) upon p53 [GeneID=7157] activation."} {"geneset":"WEI_MIR34A_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEI_MIR34A_TARGETS","description":"Potential direct target genes for MIR34A [GeneID=407040] microRNA in IMR32 cells (neuroblastoma)."} {"geneset":"WEI_MYCN_TARGETS_WITH_E_BOX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEI_MYCN_TARGETS_WITH_E_BOX","description":"Genes whose promoters contain E-box motifs and whose expression changed in MYCN-3 cells (neuroblastoma) upon induction of MYCN [GeneID=4613]."} {"geneset":"LIAO_HAVE_SOX4_BINDING_SITES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIAO_HAVE_SOX4_BINDING_SITES","description":"Genes up-regulated in the samples with intrahepatic metastatic hepatocellular carcinoma (HCC) vs primary HCC that also have putative binding sites for SOX4 [GeneID=6659]."} {"geneset":"LIAO_METASTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIAO_METASTASIS","description":"Genes up-regulated in the samples with intrahepatic metastatic hepatocellular carcinoma (HCC) vs primary HCC."} {"geneset":"HASEGAWA_TUMORIGENESIS_BY_RET_C634R","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASEGAWA_TUMORIGENESIS_BY_RET_C634R","description":"Genes up-regulated in salivary, thyroid and mammary gland carcinomas developed in transgenic mice carrying RET [GeneID=5979] allele with the MEN2A mutation (C634R)."} {"geneset":"TONG_INTERACT_WITH_PTTG1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TONG_INTERACT_WITH_PTTG1","description":"Proteins that interact with PTTG1 [GeneID=9232], based on protein array."} {"geneset":"SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_UP","description":"Cell cycle genes up-regulated in H1299 cells (lung cancer) after overexpression of either P53 or P73 [GeneID=7157;7161]."} {"geneset":"SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN","description":"Cell cycle genes down-regulated in H1299 cells (lung cancer) after overexpression of either P53 or P73 [GeneID=7157;7161]."} {"geneset":"SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_UP","description":"Genes that were inversely correlated in H1299 cells (lung cancer): up-regulated by P53 [GeneID=7157] and down-regulated by P73 [GeneID=7161]."} {"geneset":"SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN","description":"Genes that were inversely correlated in H1299 cells (lung cancer): down-regulated by P53 [GeneID=7157] and up-regulated by P73 [GeneID=7161]."} {"geneset":"GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_UP","description":"Genes up-regulated in glioblastoma cell lines displaying spherical growth (cluster-1) compared to those displaying semiadherent or adherent growth phenotype (cluster-2)."} {"geneset":"GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN","description":"Genes down-regulated in glioblastoma cell lines displaying spherical growth (cluster-1) compared to those displaying semiadherent or adherent growth phenotype (cluster-2)."} {"geneset":"SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_UP","description":"Genes up-regulated in 293 cells (embryonic kidney) expressing polymorphic variants S427G (SNP ID=rs2070235) or I624M (SNP ID=rs11556379) of BMYB [GeneID=4605]."} {"geneset":"SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_DN","description":"Genes down-regulated in 293 cells (embryonic kidney) expressing polymorphic variants S427G (SNP ID=rs2070235) or I624M (SNP ID=rs11556379) of BMYB [GeneID=4605]."} {"geneset":"GOUYER_TATI_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOUYER_TATI_TARGETS_UP","description":"Genes up-regulated in constitutively invasive HT-29 5M21 cells (colon cancer) vs those expressing functionally inactive TATI [GeneID=6690]."} {"geneset":"GOUYER_TATI_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOUYER_TATI_TARGETS_DN","description":"Genes down-regulated in constitutively invasive HT-29 5M21 cells (colon cancer) vs those expressing functionally inactive TATI [GeneID=6690]."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_UP","description":"Genes up-regulated in EVSA-T cells (breast cancer) treated THC (delta-9-tetrahydrocannabinol) [PubChem=6610319]."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_DN","description":"Genes down-regulated in EVSA-T cells (breast cancer) treated THC (delta-9-tetrahydrocannabinol) [PubChem=6610319]."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_8HR_5_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_8HR_5_UP","description":"Genes up-regulated in EVSA-T cells (breast cancer) treated with 5 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 8 h."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_8HR_5_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_8HR_5_DN","description":"Genes down-regulated in EVSA-T cells (breast cancer) treated with 5 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 8 h."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_8HR_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_8HR_3_UP","description":"Genes up-regulated in EVSA-T cells (breast cancer) treated with 3 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 8 h."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_8HR_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_8HR_3_DN","description":"Genes down-regulated in EVSA-T cells (breast cancer) treated with 3 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 8 h."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_24HR_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_24HR_3_UP","description":"Genes up-regulated in EVSA-T cells (breast cancer) after treatment with 3 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 24 h."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_24HR_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_24HR_3_DN","description":"Genes down-regulated in EVSA-T cells (breast cancer) after treatment with 3 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 24 h."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_24HR_5_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_24HR_5_UP","description":"Genes up-regulated in EVSA-T cells (breast cancer) treated with 5 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 24 h."} {"geneset":"CAFFAREL_RESPONSE_TO_THC_24HR_5_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAFFAREL_RESPONSE_TO_THC_24HR_5_DN","description":"Genes down-regulated in EVSA-T cells (breast cancer) treated with 5 micromolar THC (delta-9-tetrahydrocannabinol) [PubChem=6610319] for 24 h."} {"geneset":"RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_UP","description":"Angiogenic genes up-regulated in hepatocytes after knockout of VHL and HIF2A [GeneID=7428;2034]."} {"geneset":"RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_DN","description":"Angiogenic genes down-regulated in hepatocytes after knockout of VHL and HIF2A [GeneID=7428;2034]."} {"geneset":"BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_UP","description":"Genes up-regulated in the invasive ductal carcinoma (IDC) compared to the invasive lobular carcinoma (ILC), the two major pathological types of breast cancer."} {"geneset":"BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN","description":"Genes down-regulated in the invasive ductal carcinoma (IDC) compared to the invasive lobular carcinoma (ILC), the two major pathological types of breast cancer."} {"geneset":"SUH_COEXPRESSED_WITH_ID1_AND_ID2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUH_COEXPRESSED_WITH_ID1_AND_ID2_UP","description":"Genes whose expression positively correlates with that of both ID1 and ID2 [GeneID=3397;3398] genes in a cohort of 285 patients with primaly AML (acule myelogenous leukemia) [PMID=15084694]."} {"geneset":"WOTTON_RUNX_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WOTTON_RUNX_TARGETS_UP","description":"Common target genes up-regulated by all three Runx family members (RUNX1, RUNX2, and RUNX3 [GeneID=861;860;864]) in MEF cells (embryonic fibroblasts)."} {"geneset":"WOTTON_RUNX_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WOTTON_RUNX_TARGETS_DN","description":"Common target genes down-regulated by all three Runx family members (RUNX1, RUNX2, and RUNX3 [GeneID=861;860;864]) in MEF cells (embryonic fibroblasts)."} {"geneset":"FUJIWARA_PARK2_HEPATOCYTE_PROLIFERATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUJIWARA_PARK2_HEPATOCYTE_PROLIFERATION_UP","description":"Genes commonly up-regulated in both non-tumorous and tumorous liver tissues of PARK2 [GeneID=5071] knockout mice."} {"geneset":"FUJIWARA_PARK2_HEPATOCYTE_PROLIFERATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUJIWARA_PARK2_HEPATOCYTE_PROLIFERATION_DN","description":"Genes commonly down-regulated in both non-tumorous and tumorous liver tissues of PARK2 [GeneID=5071] knockout mice."} {"geneset":"FUJIWARA_PARK2_IN_LIVER_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUJIWARA_PARK2_IN_LIVER_CANCER_UP","description":"Genes up-regulated in tumorous liver tissues from PARK2 [GeneID=5071] knockout mice compared to the normal, non-tumorous tissue from wild type mice."} {"geneset":"FUJIWARA_PARK2_IN_LIVER_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUJIWARA_PARK2_IN_LIVER_CANCER_DN","description":"Genes down-regulated in tumorous liver tissues from PARK2 [GeneID=5071] knockout mice compared to the normal, non-tumorous tissue from wild type mice."} {"geneset":"GARCIA_TARGETS_OF_FLI1_AND_DAX1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARCIA_TARGETS_OF_FLI1_AND_DAX1_UP","description":"Genes up-regulated in the A673 cells (Ewing sarcoma) after double knockdown of both FLI1 and DAX1 [GeneID=2313;190] by RNAi."} {"geneset":"GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN","description":"Genes down-regulated in the A673 cells (Ewing sarcoma) after double knockdown of both FLI1 and DAX1 [GeneID=2313;190] by RNAi."} {"geneset":"RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP","description":"Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors."} {"geneset":"RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN","description":"Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors."} {"geneset":"RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP","description":"Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs moderately differentiated tumors."} {"geneset":"RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN","description":"Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs moderately differentiated tumors."} {"geneset":"RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP","description":"Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors."} {"geneset":"RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN","description":"Down-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: moderately vs poorly differentiated tumors."} {"geneset":"RICKMAN_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_METASTASIS_UP","description":"Genes up-regulated in metastatic vs non-metastatic HNSCC (head and neck squamous cell carcinoma) samples."} {"geneset":"RICKMAN_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_METASTASIS_DN","description":"Genes down-regulated in metastatic vs non-metastatic HNSCC (head and neck squamous cell carcinoma) samples."} {"geneset":"FRIDMAN_SENESCENCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRIDMAN_SENESCENCE_UP","description":"Genes up-regulated in senescent cells."} {"geneset":"FRIDMAN_SENESCENCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRIDMAN_SENESCENCE_DN","description":"Genes down-regulated in senescent cells."} {"geneset":"FRIDMAN_IMMORTALIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRIDMAN_IMMORTALIZATION_DN","description":"Genes down-regulated in immortalized cell lines."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP","description":"Genes up-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 6 h."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN","description":"Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 6 h."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP","description":"Genes up-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 12 h."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN","description":"Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 12 h."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP","description":"Genes up-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN","description":"Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX1_UP","description":"Early prostate development genes (up-regulated at 6 h dihydrotestosterone [PubChem=10635]) which are also up-regulated in normal epithelium vs high grade prostatic intraepithelial neoplasia (PIN)."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX1_DN","description":"Early prostate development genes (down-regulated at 6 h dihydrotestosterone [PubChem=10635]) which are also down-regulated in normal epithelium vs high grade prostatic intraepithelial neoplasia (PIN)."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_UP","description":"Early prostate development genes (up-regulated at 6 hr dihydrotestosterone [PubChem=10635]) which are also up-regulated in high grade prostatic intraepithelial neoplasia (PIN) vs invasive cancer."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_DN","description":"Early prostate development genes (down-regulated at 6 hr dihydrotestosterone [PubChem=10635]) which are also down-regulated in high grade prostatic intraepithelial neoplasia (PIN) vs invasive cancer."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_UP","description":"Early prostate development genes (up-regulated at 6 hr dihydrotestosterone [PubChem=10635]) which are also up-regulated in localized vs metastatic prostate cancers."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_DN","description":"Early prostate development genes (down-regulated at 6 hr dihydrotestosterone [PubChem=10635]) which are also down-regulated in localized vs metastatic prostate cancers."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_UP","description":"Early prostate development genes (up-regulated at 12 hr dihydrotestosterone [PubChem=10635]) which are also up-regulated in high grade prostatic intraepithelial neoplasia (PIN) vs invasive cancer."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_DN","description":"Early prostate development genes (down-regulated at 12 hr dihydrotestosterone [PubChem=10635]) which are also down-regulated in high grade prostatic intraepithelial neoplasia (PIN) vs invasive cancer."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX6_UP","description":"Early prostate development genes (up-regulated at 48 hr dihydrotestosterone [PubChem=10635]) which are also up-regulated in high grade prostatic intraepithelial neoplasia (PIN) vs invasive cancer."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX6_DN","description":"Early prostate development genes (down-regulated at 48 hr dihydrotestosterone [PubChem=10635]) which are also down-regulated in high grade prostatic intraepithelial neoplasia (PIN) vs invasive cancer."} {"geneset":"SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP","description":"Predicted targets of SOX9 [GeneID=6662] that are up-regulated during early prostate development."} {"geneset":"SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN","description":"Predicted targets of SOX9 [GeneID=6662] that are down-regulated during early prostate development."} {"geneset":"KOYAMA_SEMA3B_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOYAMA_SEMA3B_TARGETS_UP","description":"Genes up-regulated in NCI-H1299 cells (large cell neuroendocrine carcinoma) stably expressing SEMA3B [GeneID=7869]."} {"geneset":"KOYAMA_SEMA3B_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOYAMA_SEMA3B_TARGETS_DN","description":"Genes down-regulated in NCI-H1299 cells (large cell neuroendocrine carcinoma) stably expressing SEMA3B [GeneID=7869]."} {"geneset":"COURTOIS_SENESCENCE_TRIGGERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COURTOIS_SENESCENCE_TRIGGERS","description":"Genes that trigger senescence in vitro and in vivo."} {"geneset":"RICKMAN_HEAD_AND_NECK_CANCER_A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_HEAD_AND_NECK_CANCER_A","description":"Cluster a: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC)."} {"geneset":"SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX3","description":"Early prostate development genes (up-regulated at 6 hr dihydrotestosterone [PubChem=10635]) which are also up-regulated in lower grade vs higher grade locally invasive prostate cancers."} {"geneset":"RICKMAN_HEAD_AND_NECK_CANCER_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_HEAD_AND_NECK_CANCER_B","description":"Cluster b: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC)."} {"geneset":"RICKMAN_HEAD_AND_NECK_CANCER_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_HEAD_AND_NECK_CANCER_C","description":"Cluster c: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC)."} {"geneset":"RICKMAN_HEAD_AND_NECK_CANCER_D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_HEAD_AND_NECK_CANCER_D","description":"Cluster d: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC)."} {"geneset":"RICKMAN_HEAD_AND_NECK_CANCER_E","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_HEAD_AND_NECK_CANCER_E","description":"Cluster e: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC)."} {"geneset":"RICKMAN_HEAD_AND_NECK_CANCER_F","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RICKMAN_HEAD_AND_NECK_CANCER_F","description":"Cluster f: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC)."} {"geneset":"WU_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_CELL_MIGRATION","description":"Genes associated with migration rate of 40 human bladder cancer cells."} {"geneset":"TAGHAVI_NEOPLASTIC_TRANSFORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAGHAVI_NEOPLASTIC_TRANSFORMATION","description":"Genes that cooperate with MYC and TBX2 [GeneID=4609;6909] to transform MEF cells (embryo fibroblasts)."} {"geneset":"COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP","description":"Genes up-regulated in pilocytic astrocytoma compared to glioblastoma samples."} {"geneset":"COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_DN","description":"Genes down-regulated in pilocytic astrocytoma compared to glioblastoma samples."} {"geneset":"BALDWIN_PRKCI_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BALDWIN_PRKCI_TARGETS_UP","description":"Genes up-regulated in U87MG cells (glioblastoma multiforme) after knockdown of PRKCI [GeneID=5584] by RNAi."} {"geneset":"GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP","description":"Genes up-regulated in MMH-RT cells (hepatocytes displaying an invasive, metastatic phenotype) during epithelial to mesenchymal transition (EMT)."} {"geneset":"GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN","description":"Genes down-regulated in MMH-RT cells (hepatocytes displaying an invasive, metastatic phenotype) during epithelial to mesenchymal transition (EMT)."} {"geneset":"HE_PTEN_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HE_PTEN_TARGETS_UP","description":"Genes up-regulated in the intestine after the tissue specific knockout of PTEN [GeneID=5728] by Cre-lox."} {"geneset":"HE_PTEN_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HE_PTEN_TARGETS_DN","description":"Genes down-regulated in the intestine after the tissue specific knockout of PTEN [GeneID=5728] by Cre-lox."} {"geneset":"AMIT_DELAYED_EARLY_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_DELAYED_EARLY_GENES","description":"Delayed early genes (DEG) which are coordinately down-regulated in multiple epithelial tumor types."} {"geneset":"DEN_INTERACT_WITH_LCA5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DEN_INTERACT_WITH_LCA5","description":"Proteins shown to interact with LCA5 [GeneID=167691] in vivo."} {"geneset":"PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP","description":"Genes up-regulated in post-GC, BCL6 [GeneID=604] dependent B cell non-Hodgkin's lymphoma (B-NHL) vs MYC [GeneID=4609] driven pre-GC lymphoma."} {"geneset":"PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN","description":"Genes down-regulated in post-GC, BCL6 [GeneID=604] dependent B cell non-Hodgkin's lymphoma (B-NHL) vs MYC [GeneID=4609] driven pre-GC lymphoma."} {"geneset":"BENPORATH_ES_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_ES_1","description":"Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies."} {"geneset":"BENPORATH_ES_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_ES_2","description":"Set 'Set 'ES exp2': genes overexpressed in human embryonic stem cells according to a meta-analysis of 8 profiling studies."} {"geneset":"BENPORATH_NANOG_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_NANOG_TARGETS","description":"Set 'Nanog targets': genes upregulated and identified by ChIP on chip as Nanog [GeneID=79923] transcription factor targets in human embryonic stem cells."} {"geneset":"BENPORATH_OCT4_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_OCT4_TARGETS","description":"Set 'Oct4 targets': genes upregulated and identified by ChIP on chip as OCT4 [GeneID=5460] transcription factor targets in human embryonic stem cells."} {"geneset":"BENPORATH_SOX2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_SOX2_TARGETS","description":"Set 'Sox2 targets': genes upregulated and identified by ChIP on chip as SOX2 [GeneID=6657] transcription factor targets in human embryonic stem cells."} {"geneset":"BENPORATH_NOS_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_NOS_TARGETS","description":"Set 'NOS targets': genes upregulated and identified by ChIP on chip as targets of the transcription factors NANOG , OCT4, and Sox2 [GeneID=79923;5460;6657] (NOS) in human embryonic stem cells."} {"geneset":"BENPORATH_SUZ12_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_SUZ12_TARGETS","description":"Set 'Suz12 targets': genes identified by ChIP on chip as targets of the Polycomb protein SUZ12 [GeneID=23512] in human embryonic stem cells."} {"geneset":"BENPORATH_EED_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_EED_TARGETS","description":"Set 'Eed targets': genes identified by ChIP on chip as targets of the Polycomb protein EED [GeneID=8726] in human embryonic stem cells."} {"geneset":"BENPORATH_ES_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_ES_WITH_H3K27ME3","description":"Set 'H3K27 bound': genes posessing the trimethylated H3K27 (H3K27me3) mark in their promoters in human embryonic stem cells, as identified by ChIP on chip."} {"geneset":"BENPORATH_PRC2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_PRC2_TARGETS","description":"Set 'PRC2 targets': Polycomb Repression Complex 2 (PRC) targets; identified by ChIP on chip on human embryonic stem cells as genes that: posess the trimethylated H3K27 mark in their promoters and are bound by SUZ12 [GeneID=23512] and EED [GeneID=8726] Polycomb proteins."} {"geneset":"BENPORATH_MYC_TARGETS_WITH_EBOX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_MYC_TARGETS_WITH_EBOX","description":"Set 'Myc targets1': targets of c-Myc [GeneID=4609] identified by ChIP on chip in cultured cell lines, focusing on E-box-containing genes; high affinity bound subset"} {"geneset":"BENPORATH_MYC_MAX_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_MYC_MAX_TARGETS","description":"Set 'Myc targets2': targets of c-Myc [GeneID=4609] and Max [GeneID=4149] identified by ChIP on chip in a Burkitt's lymphoma cell line; overlap set."} {"geneset":"BENPORATH_CYCLING_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_CYCLING_GENES","description":"Genes showing cell-cycle stage-specific expression [PMID=12058064]."} {"geneset":"BENPORATH_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_PROLIFERATION","description":"Set 'Proliferation Cluster': genes defined in human breast tumor expression data."} {"geneset":"PETRETTO_CARDIAC_HYPERTROPHY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETRETTO_CARDIAC_HYPERTROPHY","description":"Genes that correlated most highly with left ventricular mass (LVM) index."} {"geneset":"STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP","description":"Genes up-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region."} {"geneset":"STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN","description":"Genes down-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region."} {"geneset":"STARK_HYPPOCAMPUS_22Q11_DELETION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STARK_HYPPOCAMPUS_22Q11_DELETION_UP","description":"Genes up-regulated in hyppocampus of mice carrying a hemizygotic microdeletion in the 22q11.2 region."} {"geneset":"STARK_HYPPOCAMPUS_22Q11_DELETION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STARK_HYPPOCAMPUS_22Q11_DELETION_DN","description":"Genes down-regulated in hyppocampus of mice carrying a hemizygotic microdeletion in the 22q11.2 region."} {"geneset":"STARK_BRAIN_22Q11_DELETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STARK_BRAIN_22Q11_DELETION","description":"Genes located outside the microdeletion region in 22q11 which were differentially expressed in the same manner both in hyppocampus and prefrontal cortex."} {"geneset":"BENPORATH_ES_CORE_NINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_ES_CORE_NINE","description":"Set 'Core 9': 'embryonic stem cell' transcription regulators that are preferentially and coordinately overexpressed in the high-grade, ER-negative breast cancer tumors."} {"geneset":"BENPORATH_ES_CORE_NINE_CORRELATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENPORATH_ES_CORE_NINE_CORRELATED","description":"Breast cancer compendium: 100 transcription regulators showing most correlated expression with the 9 'embryonic stem cell' transcription factors that are preferentially and coordinately overexpressed in the high-grade, ER-negative breast cancer tumors."} {"geneset":"PETRETTO_BLOOD_PRESSURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETRETTO_BLOOD_PRESSURE_UP","description":"Genes that are most strongly positively correlated with systolic blood pressure (SBP)."} {"geneset":"PETRETTO_BLOOD_PRESSURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETRETTO_BLOOD_PRESSURE_DN","description":"Genes that are most strongly negatively correlated with systolic blood pressure (SBP)."} {"geneset":"PETRETTO_HEART_MASS_QTL_CIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETRETTO_HEART_MASS_QTL_CIS_UP","description":"Up-regulated cis-regulated expression quantitative loci (cis-eQTL) in the heart that colocalize with previously mapped cardiac mass QTLs."} {"geneset":"PETRETTO_HEART_MASS_QTL_CIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETRETTO_HEART_MASS_QTL_CIS_DN","description":"Down-regulated cis-regulated expression quantitative loci (cis-eQTL) in the heart that colocalize with previously mapped cardiac mass QTLs."} {"geneset":"PETRETTO_LEFT_VENTRICLE_MASS_QTL_CIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETRETTO_LEFT_VENTRICLE_MASS_QTL_CIS_UP","description":"Up-regulated cis-regulated expression quantitative loci (cis-eQTL) in the heart that were identified as candidate genes for the regulation of left ventricle mass (LVM)."} {"geneset":"PETRETTO_LEFT_VENTRICLE_MASS_QTL_CIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETRETTO_LEFT_VENTRICLE_MASS_QTL_CIS_DN","description":"Down-regulated cis-regulated expression quantitative loci (cis-eQTL) in the heart that were identified as candidate genes for the regulation of left ventricle mass (LVM)."} {"geneset":"AMIT_EGF_RESPONSE_20_HELA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_20_HELA","description":"Genes whose expression peaked at 20 min after stimulation of HeLa cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_40_HELA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_40_HELA","description":"Genes whose expression peaked at 40 min after stimulation of HeLa cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_60_HELA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_60_HELA","description":"Genes whose expression peaked at 60 min after stimulation of HeLa cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_120_HELA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_120_HELA","description":"Genes whose expression peaked at 120 min after stimulation of HeLa cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_240_HELA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_240_HELA","description":"Genes whose expression peaked at 240 min after stimulation of HeLa cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_480_HELA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_480_HELA","description":"Genes whose expression peaked at 480 min after stimulation of HeLa cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_20_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_20_MCF10A","description":"Genes whose expression peaked at 20 min after stimulation of MCF10A cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_40_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_40_MCF10A","description":"Genes whose expression peaked at 40 min after stimulation of MCF10A cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_60_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_60_MCF10A","description":"Genes whose expression peaked at 60 min after stimulation of MCF10A cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_120_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_120_MCF10A","description":"Genes whose expression peaked at 120 min after stimulation of MCF10A cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_240_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_240_MCF10A","description":"Genes whose expression peaked at 240 min after stimulation of MCF10A cells with EGF [GeneID=1950]."} {"geneset":"AMIT_EGF_RESPONSE_480_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_EGF_RESPONSE_480_MCF10A","description":"Genes whose expression peaked at 480 min after stimulation of MCF10A cells with EGF [GeneID=1950]."} {"geneset":"AMIT_SERUM_RESPONSE_20_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_SERUM_RESPONSE_20_MCF10A","description":"Genes whose expression peaked at 20 min after stimulation of MCF10A cells with serum."} {"geneset":"AMIT_SERUM_RESPONSE_40_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_SERUM_RESPONSE_40_MCF10A","description":"Genes whose expression peaked at 40 min after stimulation of MCF10A cells with serum."} {"geneset":"AMIT_SERUM_RESPONSE_60_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_SERUM_RESPONSE_60_MCF10A","description":"Genes whose expression peaked at 60 min after stimulation of MCF10A cells with serum."} {"geneset":"AMIT_SERUM_RESPONSE_120_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_SERUM_RESPONSE_120_MCF10A","description":"Genes whose expression peaked at 120 min after stimulation of MCF10A cells with serum."} {"geneset":"AMIT_SERUM_RESPONSE_240_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_SERUM_RESPONSE_240_MCF10A","description":"Genes whose expression peaked at 240 min after stimulation of MCF10A cells with serum."} {"geneset":"AMIT_SERUM_RESPONSE_480_MCF10A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMIT_SERUM_RESPONSE_480_MCF10A","description":"Genes whose expression peaked at 480 min after stimulation of MCF10A cells with serum."} {"geneset":"GEORGES_CELL_CYCLE_MIR192_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GEORGES_CELL_CYCLE_MIR192_TARGETS","description":"Experimentally validated direct targets of MIR192 [GeneID=406967] microRNA; MIR192 caused cell cycle arrest in HCT116 cells (colon cancer)."} {"geneset":"GEORGES_TARGETS_OF_MIR192_AND_MIR215","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GEORGES_TARGETS_OF_MIR192_AND_MIR215","description":"Genes down-regulated in HCT116 cells (colon cancer) by expression of MIR192 or MIR215 [GeneID=406967;406997] at 24 h."} {"geneset":"SHEN_SMARCA2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEN_SMARCA2_TARGETS_UP","description":"Genes whose expression positively correlated with that of SMARCA2 [GeneID=6595] in prostate cancer samples."} {"geneset":"SHEN_SMARCA2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEN_SMARCA2_TARGETS_DN","description":"Genes whose expression negatively correlated with that of SMARCA2 [GeneID=6595] in prostate cancer samples."} {"geneset":"LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT","description":"Genes downregulated in MCF10A cells (breast cancer) co-cultured with cancer-associated fibroblasts (CAF)."} {"geneset":"SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN","description":"Selected genes down-regulated in inflammatory monocytes infiltrating hepatocellular carcinoma (HCC)."} {"geneset":"SAKAI_TUMOR_INFILTRATING_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAKAI_TUMOR_INFILTRATING_MONOCYTES_UP","description":"Selected genes up-regulated in inflammatory monocytes infiltrating hepatocellular carcinoma (HCC)."} {"geneset":"SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN","description":"Selected genes down-regulated in peripheral blood monocytes (PBMC) of patients with hepatocellular carcinoma (HCC) compared to those with chronic hepatitis."} {"geneset":"JEON_SMAD6_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JEON_SMAD6_TARGETS_UP","description":"Genes up-regulated in H1299 cells (lung cancer) upon knockdown of SMAD6 [GeneID=4091] by RNAi."} {"geneset":"JEON_SMAD6_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JEON_SMAD6_TARGETS_DN","description":"Genes down-regulated in H1299 cells (lung cancer) upon knockdown of SMAD6 [GeneID=4091] by RNAi."} {"geneset":"WANG_PROSTATE_CANCER_ANDROGEN_INDEPENDENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_PROSTATE_CANCER_ANDROGEN_INDEPENDENT","description":"Genes changed in prostate cancer: androgen independent vs androgen dependent samples."} {"geneset":"SUNG_METASTASIS_STROMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUNG_METASTASIS_STROMA_UP","description":"Genes up-regulated in metastatic vs non-metastatic stromal cells originated from either bone or prostate tissues."} {"geneset":"SUNG_METASTASIS_STROMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUNG_METASTASIS_STROMA_DN","description":"Genes down-regulated in metastatic vs non-metastatic stromal cells originated from either bone or prostate tissues."} {"geneset":"SHIN_B_CELL_LYMPHOMA_CLUSTER_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIN_B_CELL_LYMPHOMA_CLUSTER_1","description":"Cluster 1 of genes distinguishing among different B lymphocyte neoplasms."} {"geneset":"SHIN_B_CELL_LYMPHOMA_CLUSTER_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIN_B_CELL_LYMPHOMA_CLUSTER_2","description":"Cluster 2 of genes distinguishing among different B lymphocyte neoplasms."} {"geneset":"SHIN_B_CELL_LYMPHOMA_CLUSTER_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIN_B_CELL_LYMPHOMA_CLUSTER_3","description":"Cluster 3 of genes distinguishing among different B lymphocyte neoplasms."} {"geneset":"SHIN_B_CELL_LYMPHOMA_CLUSTER_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIN_B_CELL_LYMPHOMA_CLUSTER_5","description":"Cluster 5 of genes distinguishing among different B lymphocyte neoplasms."} {"geneset":"SHIN_B_CELL_LYMPHOMA_CLUSTER_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIN_B_CELL_LYMPHOMA_CLUSTER_6","description":"Cluster 6 of genes distinguishing among different B lymphocyte neoplasms."} {"geneset":"SHIN_B_CELL_LYMPHOMA_CLUSTER_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIN_B_CELL_LYMPHOMA_CLUSTER_7","description":"Cluster 7 of genes distinguishing among different B lymphocyte neoplasms."} {"geneset":"SHIN_B_CELL_LYMPHOMA_CLUSTER_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIN_B_CELL_LYMPHOMA_CLUSTER_8","description":"Cluster 8 of genes distinguishing among different B lymphocyte neoplasms."} {"geneset":"SHIN_B_CELL_LYMPHOMA_CLUSTER_9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIN_B_CELL_LYMPHOMA_CLUSTER_9","description":"Cluster 9 of genes distinguishing among different B lymphocyte neoplasms."} {"geneset":"ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP","description":"Genes up-regulated in BxPC3 cells (pancreatic cancer) after treatment with TNF [GeneID=7124] or IKI-1, an inhibitor of IkappaB kinase (IKK)."} {"geneset":"ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN","description":"Genes down-regulated in BxPC3 cells (pancreatic cancer) after treatment with TNF [GeneID=7124] or IKI-1, an inhibitor of IkappaB kinase (IKK)."} {"geneset":"MORI_PRE_BI_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_PRE_BI_LYMPHOCYTE_UP","description":"Up-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Pre-BI stage."} {"geneset":"MORI_PRE_BI_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_PRE_BI_LYMPHOCYTE_DN","description":"Down-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Pre-BI stage."} {"geneset":"MORI_LARGE_PRE_BII_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_LARGE_PRE_BII_LYMPHOCYTE_UP","description":"Up-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Large Pre-BII stage."} {"geneset":"MORI_LARGE_PRE_BII_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_LARGE_PRE_BII_LYMPHOCYTE_DN","description":"Down-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Large Pre-BII stage."} {"geneset":"MORI_SMALL_PRE_BII_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_SMALL_PRE_BII_LYMPHOCYTE_UP","description":"Up-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Small Pre-BII stage."} {"geneset":"MORI_SMALL_PRE_BII_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_SMALL_PRE_BII_LYMPHOCYTE_DN","description":"Down-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Small Pre-BII stage."} {"geneset":"MORI_IMMATURE_B_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_IMMATURE_B_LYMPHOCYTE_UP","description":"Up-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the immature B stage."} {"geneset":"MORI_IMMATURE_B_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_IMMATURE_B_LYMPHOCYTE_DN","description":"Down-regulated genes in the B lymphocyte developmental signature based on expression profiling of lymphomas from the Emu-myc transgenic mice: the immature B stage."} {"geneset":"MORI_MATURE_B_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_MATURE_B_LYMPHOCYTE_UP","description":"Up-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the mature B"} {"geneset":"MORI_MATURE_B_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_MATURE_B_LYMPHOCYTE_DN","description":"Down-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the mature B"} {"geneset":"MORI_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_PLASMA_CELL_UP","description":"Up-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: plasma cell."} {"geneset":"MORI_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_PLASMA_CELL_DN","description":"Down-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: plasma cell."} {"geneset":"MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP","description":"Genes correlated with the early tumor onset in the Emu-myc transgenic mouse lymphoma model."} {"geneset":"MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_DN","description":"Genes correlated with the late tumor onset in the Emu-myc transgenic mouse lymphoma model."} {"geneset":"COLLIS_PRKDC_SUBSTRATES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLLIS_PRKDC_SUBSTRATES","description":"Substrates of PRKDC [GeneID=5591]."} {"geneset":"COLLIS_PRKDC_REGULATORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLLIS_PRKDC_REGULATORS","description":"Proteins that regulate activity of PRKDC [GeneID=5591]."} {"geneset":"TOMIDA_LUNG_CANCER_POOR_SURVIVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOMIDA_LUNG_CANCER_POOR_SURVIVAL","description":"Metastatic signature genes that best distinguished between favorable and unfavorable prognosis for the non-small cell lung cancer (NSCLC) patients."} {"geneset":"LEE_TARGETS_OF_PTCH1_AND_SUFU_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_TARGETS_OF_PTCH1_AND_SUFU_UP","description":"Genes up-regulated in medulloblastoma tumors from animals with inactivating mutations of one copy of PTCH1 or SUFU [GeneID=5727;51684] in conjunction with TP53 [GeneID=7157] loss."} {"geneset":"LEE_TARGETS_OF_PTCH1_AND_SUFU_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_TARGETS_OF_PTCH1_AND_SUFU_DN","description":"Genes down-regulated in medulloblastoma tumors from animals with inactivating mutations of one copy of PTCH1 or SUFU [GeneID=5727;51684] in conjunction with TP53 [GeneID=7157] loss."} {"geneset":"KAUFFMANN_DNA_REPAIR_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAUFFMANN_DNA_REPAIR_GENES","description":"Genes involved in DNA repair, compiled manually by the authors."} {"geneset":"KAUFFMANN_DNA_REPLICATION_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAUFFMANN_DNA_REPLICATION_GENES","description":"Genes involved in DNA replication, compiled manually by the authors."} {"geneset":"NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON","description":"Genes within amplicon 1q21 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_1Q32_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_1Q32_AMPLICON","description":"Genes within amplicon 1q32 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_5P15_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_5P15_AMPLICON","description":"Genes within amplicon 5p15 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_6P24_P22_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_6P24_P22_AMPLICON","description":"Genes within amplicon 6p24-p22 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_7P22_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_7P22_AMPLICON","description":"Genes within amplicon 7p22 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_7P15_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_7P15_AMPLICON","description":"Genes within amplicon 7p15 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_7Q21_Q22_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_7Q21_Q22_AMPLICON","description":"Genes within amplicon 7q21-q22 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_8P12_P11_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_8P12_P11_AMPLICON","description":"Genes within amplicon 8p12-p11 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON","description":"Genes within amplicon 8q12-q22 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON","description":"Genes within amplicon 8q23-q24 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_10Q22_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_10Q22_AMPLICON","description":"Genes within amplicon 10q22 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_11Q12_Q14_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_11Q12_Q14_AMPLICON","description":"Genes within amplicon 11q12-q14 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_12Q13_Q21_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_12Q13_Q21_AMPLICON","description":"Genes within amplicon 12q13-q21 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_12Q24_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_12Q24_AMPLICON","description":"Genes within amplicon 12q24 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_14Q22_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_14Q22_AMPLICON","description":"Genes within amplicon 14q22 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_15Q26_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_15Q26_AMPLICON","description":"Genes within amplicon 15q26 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_16P13_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_16P13_AMPLICON","description":"Genes within amplicon 16p13 identified in a study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_16Q24_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_16Q24_AMPLICON","description":"Genes within amplicon 16q24 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_17P11_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_17P11_AMPLICON","description":"Genes within amplicon 17p11 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_17Q11_Q21_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_17Q11_Q21_AMPLICON","description":"Genes within amplicon 17q11-q21 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON","description":"Genes within amplicon 17q21-q25 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_19P13_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_19P13_AMPLICON","description":"Genes within amplicon 19p13 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_19Q13.1_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_19Q13.1_AMPLICON","description":"Genes within amplicon 19q13.1 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_19Q13.4_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_19Q13.4_AMPLICON","description":"Genes within amplicon 19q13.4 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_20P13_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_20P13_AMPLICON","description":"Genes within amplicon 20p13 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_20Q11_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_20Q11_AMPLICON","description":"Genes within amplicon 20q11 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_20Q12_Q13_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_20Q12_Q13_AMPLICON","description":"Genes within amplicon 20q12-q13 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_21Q22_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_21Q22_AMPLICON","description":"Genes within amplicon 21q22 identified in a copy alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_BREAST_CANCER_22Q13_AMPLICON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_BREAST_CANCER_22Q13_AMPLICON","description":"Genes within amplicon 22q13 identified in a copy number alterations study of 191 breast tumor samples."} {"geneset":"NIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER","description":"Genes both mutated and amplified in a panel of 191 breast tumor samples."} {"geneset":"WHITEHURST_PACLITAXEL_SENSITIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITEHURST_PACLITAXEL_SENSITIVITY","description":"Genes that reduced viability of NCI-H1155 cells (non-small-cell lung cancer, NSCLC) in the presence of otherwise sublethal concentrations of paclitaxel [PubChem=4666], based on RNAi synthetic lethal screen."} {"geneset":"STEGMEIER_PREMITOTIC_CELL_CYCLE_REGULATORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEGMEIER_PREMITOTIC_CELL_CYCLE_REGULATORS","description":"Pre-mitotic cell cycle regulators (CDC) identified in an shRNA screen of the ubiquitin pathway components."} {"geneset":"TESAR_ALK_TARGETS_HUMAN_ES_4D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_ALK_TARGETS_HUMAN_ES_4D_DN","description":"Genes down-regulated in hES cells (human embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=16079008]."} {"geneset":"TESAR_ALK_TARGETS_HUMAN_ES_5D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_ALK_TARGETS_HUMAN_ES_5D_UP","description":"Genes up-regulated in hES cells (human embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]."} {"geneset":"TESAR_ALK_TARGETS_HUMAN_ES_5D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_ALK_TARGETS_HUMAN_ES_5D_DN","description":"Genes down-regulated in hES cells (human embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]."} {"geneset":"JI_METASTASIS_REPRESSED_BY_STK11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JI_METASTASIS_REPRESSED_BY_STK11","description":"Adenocarcinoma metastatic program genes up-regulated in A549 and H2126 cells (lung cancer) lacking functional STK11 [GeneID=6794] but down-regulated by the normal gene."} {"geneset":"GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11","description":"Genes down-regulated in BJAB cell line (B lymphocyte) after expression of the viral microRNA miR-K12-11 which functions as an ortholog of cellular MIR155 [GeneID=406947]."} {"geneset":"CHEN_NEUROBLASTOMA_COPY_NUMBER_GAINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_NEUROBLASTOMA_COPY_NUMBER_GAINS","description":"High-grade amplification (copy number, CN >= 5) detected in primary neuroblastoma samples."} {"geneset":"TCGA_GLIOBLASTOMA_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCGA_GLIOBLASTOMA_COPY_NUMBER_UP","description":"Genes up-regulated and displaying increased copy number in glioblastoma samples."} {"geneset":"TCGA_GLIOBLASTOMA_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCGA_GLIOBLASTOMA_COPY_NUMBER_DN","description":"Genes down-regulated and displaying decreased copy number in glioblastoma samples."} {"geneset":"DING_LUNG_CANCER_MUTATED_SIGNIFICANTLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DING_LUNG_CANCER_MUTATED_SIGNIFICANTLY","description":"The lung adenocarcinoma TSP (tumor sequencing project) genes that were found significantly mutated by at least one method."} {"geneset":"DING_LUNG_CANCER_MUTATED_FREQUENTLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DING_LUNG_CANCER_MUTATED_FREQUENTLY","description":"The lung adenocarcinoma TSP (tumor sequencing project) genes with significantly higher frequencies of nonsense, splice site, and frame-shift mutations."} {"geneset":"DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER","description":"The lung adenocarcinoma TSP (tumor sequencing project) genes showing strong correlation between DNA copy number variation and gene expression."} {"geneset":"ONDER_CDH1_TARGETS_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONDER_CDH1_TARGETS_2_UP","description":"Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi."} {"geneset":"ONDER_CDH1_TARGETS_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONDER_CDH1_TARGETS_2_DN","description":"Genes down-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi."} {"geneset":"ONDER_CDH1_TARGETS_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONDER_CDH1_TARGETS_1_UP","description":"Genes up-regulated in HMLE cells (mmortalized nontransformed mammary epithelial) by expression of a dominant-negative form of E-cadhedrin (CDH1) [GeneID=999]."} {"geneset":"ONDER_CDH1_TARGETS_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONDER_CDH1_TARGETS_1_DN","description":"Genes down-regulated in HMLE cells (mmortalized nontransformed mammary epithelial) by expression of a dominant-negative form of E-cadhedrin (CDH1) [GeneID=999]."} {"geneset":"ONDER_CDH1_TARGETS_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONDER_CDH1_TARGETS_3_UP","description":"Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelial) cells after loss of function of E-cadhedrin (CDH1) [GeneID=999], which was achieved either by RNAi knockdown or by expression of a dominan-negative form of CDH1."} {"geneset":"ONDER_CDH1_TARGETS_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONDER_CDH1_TARGETS_3_DN","description":"Genes down-regulated in HMLE cells (immortalized nontransformed mammary epithelial) cells after loss of function of E-cadhedrin (CDH1) [GeneID=999], which was achieved either by RNAi knockdown or by expression of a dominan-negative form of CDH1."} {"geneset":"ONDER_CDH1_SIGNALING_VIA_CTNNB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONDER_CDH1_SIGNALING_VIA_CTNNB1","description":"Genes changed in HMLE cells (mmortalized nontransformed mammary epithelium) after RNAi knockdown of both CDH1 and CTNNB1 [GeneID=999;1499], compared to the knockdown of CDH1 alone."} {"geneset":"ZEILSTRA_CD44_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEILSTRA_CD44_TARGETS_UP","description":"Genes implicated in apoptosis that were up-regulated in duodenum of CD44 [GeneID=960] knockout mice."} {"geneset":"ZEILSTRA_CD44_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEILSTRA_CD44_TARGETS_DN","description":"Genes implicated in apoptosis that were down-regulated in duodenum of CD44 [GeneID=960] knockout mice."} {"geneset":"CERVERA_SDHB_TARGETS_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CERVERA_SDHB_TARGETS_2","description":"Genes present but differentially expressed between Hep3B cells (hepatocellular carcinoma, HCC) with RNAi knockdown of SDHB [GeneID=6390] and control cells."} {"geneset":"ROZANOV_MMP14_TARGETS_SUBSET","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROZANOV_MMP14_TARGETS_SUBSET","description":"Genes linked to the ECM maintenance and angiogenesis that were changed in HT1080 cells (fibrosarcoma) over-expressing MMP14 [GeneID=4323] compared to those with knockdown of the gene by RNAi."} {"geneset":"ROZANOV_MMP14_CORRELATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROZANOV_MMP14_CORRELATED","description":"Genes whose expression most uniformly correlated with that of MMP14 [GeneID=4323] both in HT1080 cells (fibrosarcoma) and in 190 human tumors."} {"geneset":"ROZANOV_MMP14_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROZANOV_MMP14_TARGETS_UP","description":"Genes up-regulated in HT1080 cells (fibrosarcoma) over-expressing MMP14 [GeneID=4323] compared to those with knockdown of the gene by RNAi."} {"geneset":"ROZANOV_MMP14_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROZANOV_MMP14_TARGETS_DN","description":"Genes down-regulated in HT1080 cells (fibrosarcoma) over-expressing MMP14 [GeneID=4323] compared to those with knockdown of the gene by RNAi."} {"geneset":"LANDEMAINE_LUNG_METASTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LANDEMAINE_LUNG_METASTASIS","description":"Genes associated with metastasis of breast cancer in the lung compared to the non-lung metastasis."} {"geneset":"CERVERA_SDHB_TARGETS_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CERVERA_SDHB_TARGETS_1_UP","description":"Genes turned on in Hep3B cells (hepatocellular carcinoma, HCC) upon knockdown of SDHB [GeneID=6390] by RNAi."} {"geneset":"CERVERA_SDHB_TARGETS_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CERVERA_SDHB_TARGETS_1_DN","description":"Genes turned off in Hep3B cells (hepatocellular carcinoma, HCC) upon knockdown of SDHB [GeneID=6390] by RNAi."} {"geneset":"LE_EGR2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LE_EGR2_TARGETS_DN","description":"Genes down-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [GeneID=1959]."} {"geneset":"ROSS_ACUTE_MYELOID_LEUKEMIA_CBF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROSS_ACUTE_MYELOID_LEUKEMIA_CBF","description":"Top 100 probe sets for core-binding factor (CBF) acute myeloid leukemia (AML): contains CBFB MYH11 [GeneID=865;4629] or AML1 ETO [GeneID=861;862] fusions."} {"geneset":"BYSTRYKH_SCP2_QTL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_SCP2_QTL","description":"Genes that physically map to the hematopoietic stem cell (HSC) proliferation QTL (quantitative trait locus) Scp2."} {"geneset":"KENNY_CTNNB1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KENNY_CTNNB1_TARGETS_UP","description":"Genes up-regulated in HC11 cells (mammary epithelium) by expression of constantly active CTNNB1 [GeneID=1499]."} {"geneset":"CHEOK_RESPONSE_TO_MERCAPTOPURINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEOK_RESPONSE_TO_MERCAPTOPURINE_DN","description":"Genes specifically down-regulated in pediadric acute lymphoblastic leukemia (ALL) patients by mercaptopurine [PubChem=667490]."} {"geneset":"NELSON_RESPONSE_TO_ANDROGEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NELSON_RESPONSE_TO_ANDROGEN_DN","description":"Genes down-regulated in LNCaP cells (prostate cancer) in response to synthetic androgen R1881 [PubChem=13766]."} {"geneset":"TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP","description":"Genes up-regulated in plasma cells compared with B lymphocytes."} {"geneset":"BYSTROEM_CORRELATED_WITH_IL5_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTROEM_CORRELATED_WITH_IL5_DN","description":"Genes whose expression in bone marrow samples correlated inversely with increased levels of serum IL5 [GeneID=3567]."} {"geneset":"SWEET_KRAS_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SWEET_KRAS_TARGETS_DN","description":"Genes upregulated in control vs KRAS [GeneID=3845] knockdown in a human cell line."} {"geneset":"SHEPARD_CRUSH_AND_BURN_MUTANT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEPARD_CRUSH_AND_BURN_MUTANT_UP","description":"Human orthologs of genes up-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [GeneID=4605]."} {"geneset":"ROSS_AML_WITH_PML_RARA_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROSS_AML_WITH_PML_RARA_FUSION","description":"Top 100 probe sets for pediatric acute myeloid leukemia (AML) subtype t(15;17): has PML RARA fusion [GeneID=5371;5914]."} {"geneset":"ZUCCHI_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZUCCHI_METASTASIS_DN","description":"The 50 most down-regulated genes in primary invasive breast dutcal carcinoma (IDC) or lymph node metastases, compared to normal mammary epithelium."} {"geneset":"LEI_HOXC8_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEI_HOXC8_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblasts) by overexpression of HOXC8 [GeneID=3224]."} {"geneset":"PARK_HSC_VS_MULTIPOTENT_PROGENITORS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_HSC_VS_MULTIPOTENT_PROGENITORS_DN","description":"Genes down-regulated in long term hematopoietic stem cells (LT-HSC) compared to multipotent progenitor (MPP) cells."} {"geneset":"LEE_LIVER_CANCER_CIPROFIBRATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_CIPROFIBRATE_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) induced by ciprofibrate [PubChem=2763]."} {"geneset":"ASTON_MAJOR_DEPRESSIVE_DISORDER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ASTON_MAJOR_DEPRESSIVE_DISORDER_DN","description":"Genes down-regulated in the temporal cortex samples from patients with major depressive disorder."} {"geneset":"STANELLE_E2F1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STANELLE_E2F1_TARGETS","description":"Genes up-regulated by induction of E2F1 expression in Saos2 (osteosarcoma) cells."} {"geneset":"CHESLER_BRAIN_D6MIT150_QTL_CIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHESLER_BRAIN_D6MIT150_QTL_CIS","description":"Cis-regulatory QTLs (quantitative trait loci) found at the D6Mit150 region."} {"geneset":"SHIPP_DLBCL_CURED_VS_FATAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIPP_DLBCL_CURED_VS_FATAL_DN","description":"Top 50 down-regulated markers for the diffused large B-cell lymphoma (DLBCL) that distinguished between cured and fatal/refractory clinical outcomes."} {"geneset":"GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3","description":"Genes up-regulated in Jurkat cells (T lymphocyte) by IFN1@, and IFNB1 [GeneID=3438;3456] but not by overexpression of a constitutively active form of IRF3 [GeneID=3661]."} {"geneset":"UEDA_CENTRAL_CLOCK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/UEDA_CENTRAL_CLOCK","description":"Molecular timetable composed of 96 time-indicating genes (103 probes) in the central (suprachiasmatic nucleus (SCN)) clock."} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_FGF3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_FGF3","description":"Genes whose expression is coregulated with that of FGF3 [GeneID=2248] in hematopoietic stem cells (HSC)."} {"geneset":"GOLUB_ALL_VS_AML_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLUB_ALL_VS_AML_UP","description":"Up-regulated genes highly correlated with acute lymphoblastic leukemia (ALL) vs acute myeloid leukemia (AML)."} {"geneset":"HOUSTIS_ROS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOUSTIS_ROS","description":"Genes known to modulate ROS or whose expression changes in response to ROS"} {"geneset":"BASSO_B_LYMPHOCYTE_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BASSO_B_LYMPHOCYTE_NETWORK","description":"Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes."} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS","description":"Transcripts in hematopoietic stem cells (HSC) which are cis-regulated (i.e., modulated by a QTL (quantitative trait locus) in close proximity to the gene)."} {"geneset":"SCHUHMACHER_MYC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHUHMACHER_MYC_TARGETS_DN","description":"Genes down-regulated in P493-6 cells (Burkitt's lymphoma) induced to express MYC [GeneID=4609]."} {"geneset":"LEI_HOXC8_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEI_HOXC8_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblasts) by overexpression of HOXC8 [GeneID=3224]."} {"geneset":"CHESLER_BRAIN_QTL_CIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHESLER_BRAIN_QTL_CIS","description":"Best cis-regulated quantitative trait loci (QTLs) in the mouse genome which modulate transcription in brain tissue."} {"geneset":"ROSS_AML_WITH_CBFB_MYH11_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROSS_AML_WITH_CBFB_MYH11_FUSION","description":"Top 63 probe sets for pediatric acute myeloid leukemia (AML) subtype inv(16); has a CBFB-MYH11 fusion [GeneID=865;4629]."} {"geneset":"IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_UP","description":"Genes up-regulated during transition from L0 (non-tumor, not infected with HCV) to L1 (non-tumor, infected with HCV) in the development of hepatocellular carcinoma."} {"geneset":"IIZUKA_LIVER_CANCER_PROGRESSION_L1_G1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_PROGRESSION_L1_G1_DN","description":"Genes down-regulated during transition from L1 (non-tumor, infected with HCV) to G1 (well differentiated tumor, infected with HCV) in the development of hepatocellular carcinoma."} {"geneset":"FERRANDO_TAL1_NEIGHBORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERRANDO_TAL1_NEIGHBORS","description":"Nearest neighbors of TAL1 [GeneID=6886], based on the close agreement of their expression profiles with that of TAL1 in pediatric T cell acute lymphoblastic leukemia (T-ALL)"} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS","description":"Genes trans-regulated by the same QTL (quantitative trait loci) in brain and hematopoietic stem cells (HSC)."} {"geneset":"PENG_LEUCINE_DEPRIVATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PENG_LEUCINE_DEPRIVATION_UP","description":"Genes up-regulated in BJAB cells (B-lymphoma) after leucine [PubChem=857] deprivation."} {"geneset":"LEE_LIVER_CANCER_MYC_TGFA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_MYC_TGFA_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) tissue of MYC and TGFA [GeneID=4609;7039] double transgenic mice."} {"geneset":"IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_DN","description":"Genes down-regulated during transition from G1 (well differentiated tumor, infected with HCV) to G2 (moderately differentiated tumor, infected with HCV) in the development of hepatocellular carcinoma."} {"geneset":"GOLDRATH_HOMEOSTATIC_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_HOMEOSTATIC_PROLIFERATION","description":"Up-regulated in CD8+ [GeneID=925] T lymphocytes undergoing homeostatic proliferation (HP) versus the naive cells; these genes are not up-regulated versus effector or memory cell population."} {"geneset":"LAMB_CCND1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LAMB_CCND1_TARGETS","description":"The cyclin D1 signature: genes whose expression correlated with the levels of CCND1 [GeneID=595]."} {"geneset":"GNATENKO_PLATELET_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNATENKO_PLATELET_SIGNATURE","description":"Top 50 most up-regulated genes in human platelet cells."} {"geneset":"KIM_GERMINAL_CENTER_T_HELPER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_GERMINAL_CENTER_T_HELPER_UP","description":"Genes up-regulated in germinal center T helper cells compared to other CD4+ [GeneID=920] T lymphocyte types."} {"geneset":"SHEPARD_BMYB_MORPHOLINO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEPARD_BMYB_MORPHOLINO_DN","description":"Human orthologs of genes down-regulated in zebra fish after knockdown of BMYB [GeneID=4605] by morpholino."} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS","description":"Genes associated with the same cis-regulatory QTL (quantitative trait loci) in both brain and hematopoietic stem cells (HSC)."} {"geneset":"LEE_LIVER_CANCER_ACOX1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_ACOX1_DN","description":"Genes down-regulated in hepatocellular carcinoma of ACOX1 [GeneID=51] knockout mice."} {"geneset":"PENG_GLUCOSE_DEPRIVATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PENG_GLUCOSE_DEPRIVATION_UP","description":"Genes up-regulated in BJAB cells (B-lymphoma) after glucose [PubChem=206] deprivation."} {"geneset":"SMITH_TERT_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMITH_TERT_TARGETS_UP","description":"Genes consistently up-regulated in HMEC cells (primary mammary epithelium) upon expression of TERT [GeneID=7015] off a retroviral vector."} {"geneset":"LEE_LIVER_CANCER_MYC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_MYC_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) induced by overexpression of MYC [GeneID=4609]."} {"geneset":"MENSSEN_MYC_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MENSSEN_MYC_TARGETS","description":"Genes up-regulated by adenoviral expression of c-MYC [GeneID=4609] in HUVEC cells (umbilical vein endothelium)."} {"geneset":"IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN","description":"Genes down-regulated during transition from L0 (non-tumor, not infected with HCV) to L1 (non-tumor, infected with HCV) in the development of hepatocellular carcinoma."} {"geneset":"JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP","description":"Genes up-regulated during epithelial to mesenchymal transition (EMT) induced by TGFB1 [GeneID=7040] in the EpH4 cells (mammary epithelium cell line transformed by HRAS [GeneID=3265])."} {"geneset":"DER_IFN_ALPHA_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DER_IFN_ALPHA_RESPONSE_UP","description":"Genes up-regulated in HT1080 cells (fibrosarcoma) by treatment with interferon alpha for 6 h."} {"geneset":"KANNAN_TP53_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANNAN_TP53_TARGETS_UP","description":"Primary up-regulated targets of TP53 [GeneID=7157] in the H1299 (lung cancer) cell line."} {"geneset":"PENG_GLUTAMINE_DEPRIVATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PENG_GLUTAMINE_DEPRIVATION_UP","description":"Genes up-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation."} {"geneset":"WELCH_GATA1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WELCH_GATA1_TARGETS","description":"Genes up-regulated after GATA1 [GeneID=2623] activation in G1E-ER4 cells (erythroid precursors engineered to express GATA1 upon addition of estradiol [PubChem=5757])."} {"geneset":"FRASOR_RESPONSE_TO_ESTRADIOL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRASOR_RESPONSE_TO_ESTRADIOL_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) by estradiol (E2) [PubChem=5757]."} {"geneset":"LEE_LIVER_CANCER_MYC_TGFA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_MYC_TGFA_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) tissue of MYC and TGFA [GeneID=4609;7039] double transgenic mice."} {"geneset":"FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN","description":"Genes downregulated in peripheral blood lymphocytes (PBL) from patients with well functioning kidneys more than 1-year post transplant compared to those from normal living kidney donors."} {"geneset":"DORSAM_HOXA9_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORSAM_HOXA9_TARGETS_UP","description":"HOXA9 [GeneID=3205] targets up-regulated in hematopoietic stem cells."} {"geneset":"DER_IFN_BETA_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DER_IFN_BETA_RESPONSE_DN","description":"Genes down-regulated in HT1080 (fibrosarcoma) cells by treatment with interferon beta for 6 h."} {"geneset":"IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_UP","description":"Genes up-regulated during transition from G2 (moderately differentiated tumor, infected with HCV) to G3 (poorly differentiated tumor, infected with HCV) in the development of hepatocellular carcinoma."} {"geneset":"NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN","description":"Down-regulated genes in lung tissue of smokers with chronic obstructive pulmonary disease (COPD) vs smokers without disease (GOLD-2 vs GOLD-0)."} {"geneset":"KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN","description":"Genes down-regulated in AIDS-related primary effusion lymphoma (PEL) samples compared to other tumor subtypes and normal B lymphocytes."} {"geneset":"SHEPARD_BMYB_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEPARD_BMYB_TARGETS","description":"Human orthologs of BMYB [GeneID=4605] target genes in zebra fish, identified as commonly changed in the BMYB loss of function mutant crb ('crush and burn') and after knockdown of BMYB by morpholino."} {"geneset":"KANNAN_TP53_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANNAN_TP53_TARGETS_DN","description":"Primary down-regulated targets of TP53 [GeneID=7157] in the H1299 (lung cancer) cell line."} {"geneset":"CHANG_POU5F1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANG_POU5F1_TARGETS_UP","description":"Genes up-regulated by POU5F1 [GeneID=5460] in bladder cancer cell lines."} {"geneset":"CHANG_POU5F1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANG_POU5F1_TARGETS_DN","description":"Genes down-regulated by POU5F1 [GeneID=5460] in bladder cancer cell lines."} {"geneset":"SANA_TNF_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANA_TNF_SIGNALING_DN","description":"Genes down-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by TNF [GeneID=7124]."} {"geneset":"TARTE_PLASMA_CELL_VS_PLASMABLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TARTE_PLASMA_CELL_VS_PLASMABLAST_UP","description":"Genes up-regulated in mature plasma cells compared with plasmablastic B lymphocytes."} {"geneset":"WILLERT_WNT_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILLERT_WNT_SIGNALING","description":"Genes up-regulated in NCCIT cell line (embryonic teratocarcinoma) after stimulation with WNT3A [GeneID=89780]."} {"geneset":"PENG_LEUCINE_DEPRIVATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PENG_LEUCINE_DEPRIVATION_DN","description":"Genes down-regulated in BJAB cells (B-lymphoma) after leucine [PubChem=857] deprivation."} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_RUNX1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_RUNX1","description":"Genes whose expression is coregulated with that of RUNX1 [GeneID=861] in hematopoietic stem cells (HSC)."} {"geneset":"KENNY_CTNNB1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KENNY_CTNNB1_TARGETS_DN","description":"Genes down-regulated in HC11 cells (mammary epithelium) by expression of constantly active CTNNB1 [GeneID=1499]."} {"geneset":"CHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_LD_MTX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_LD_MTX_UP","description":"Genes specifically up-regulated in pediatric acute lymphoblastic leukemia (ALL) patients by mercaptopurine [PubChem=667490] and low-dose methotrexate (LDMTX) [PubChem=4112]."} {"geneset":"WONG_IFNA2_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_IFNA2_RESISTANCE_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) cell lines resistant to IFNA2 [GeneID=3440]."} {"geneset":"CHESLER_BRAIN_QTL_TRANS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHESLER_BRAIN_QTL_TRANS","description":"Best trans-regulated quantitative trait loci (QTLs) in the mouse genome which modulate transcription in brain tissue."} {"geneset":"IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_UP","description":"Genes up-regulated during transition from G1 (well differentiated tumor, infected with HCV) to G2 (moderately differentiated tumor, infected with HCV) in the development of hepatocellular carcinoma."} {"geneset":"BECKER_TAMOXIFEN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BECKER_TAMOXIFEN_RESISTANCE_UP","description":"Genes up-regulated in a breast cancer cell line resistant to tamoxifen [PubChem=5376] compared to the parental line sensitive to the drug."} {"geneset":"SHEPARD_CRUSH_AND_BURN_MUTANT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEPARD_CRUSH_AND_BURN_MUTANT_DN","description":"Human orthologs of genes down-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [GeneID=4605]."} {"geneset":"KIM_GERMINAL_CENTER_T_HELPER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_GERMINAL_CENTER_T_HELPER_DN","description":"Genes down-regulated in germinal center T helper cells compared to other CD4+ [GeneID=920] T lymphocyte types."} {"geneset":"RADAEVA_RESPONSE_TO_IFNA1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RADAEVA_RESPONSE_TO_IFNA1_UP","description":"Genes up-regulated in primary hepatocytes and Hep3B (hepatocyte) cells in response to IFNA [GeneID=3439]."} {"geneset":"PEART_HDAC_PROLIFERATION_CLUSTER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEART_HDAC_PROLIFERATION_CLUSTER_UP","description":"Cell proliferation genes up-regulated by histone deacetylase (HDAC) inhibitors SAHA and depsipeptide [PubChem=5311;5352062]."} {"geneset":"TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN","description":"Genes down-regulated in plasma cells compared with B lymphocytes."} {"geneset":"KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_DN","description":"Down-regulated genes predicting response of patients with hepatocellular carcinoma (HCC) to combination chemotherapy with 5-fluorouracil (5-FU) [PubChem=3385] and IFN1@ [GeneID=3438]."} {"geneset":"PARK_HSC_VS_MULTIPOTENT_PROGENITORS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_HSC_VS_MULTIPOTENT_PROGENITORS_UP","description":"Genes up-regulated in long term hematopoietic stem cells (LT-HSC) compared to multipotent progenitor (MPP) cells."} {"geneset":"YAGI_AML_RELAPSE_PROGNOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGI_AML_RELAPSE_PROGNOSIS","description":"Genes associated with clinical prognosis of pediatric AML (acute myeloid leukemia): good prognosis=no relapse 3 years; poor prognosis=relapse < 1 year or no response to therapy."} {"geneset":"SHIPP_DLBCL_CURED_VS_FATAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIPP_DLBCL_CURED_VS_FATAL_UP","description":"Top 50 up-regulated markers for the diffused large B-cell lymphoma (DLBCL) that distinguished between cured and fatal/refractory clinical outcomes."} {"geneset":"FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP","description":"Genes up-regulated in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant."} {"geneset":"LEE_LIVER_CANCER_ACOX1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_ACOX1_UP","description":"Genes up-regulated in hepatocellular carcinoma of ACOX1 [GeneID=51] knockout mice."} {"geneset":"IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_DN","description":"Genes down-regulated during transition from G2 (moderately differentiated tumor, infected with HCV) to G3 (poorly differentiated tumor, infected with HCV) in the development of hepatocellular carcinoma."} {"geneset":"CHEOK_RESPONSE_TO_MERCAPTOPURINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEOK_RESPONSE_TO_MERCAPTOPURINE_UP","description":"Genes specifically up-regulated in pediadric acute lymphoblastic leukemia (ALL) patients by mercaptopurine [PubChem=667490]."} {"geneset":"UEDA_PERIFERAL_CLOCK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/UEDA_PERIFERAL_CLOCK","description":"Molecular timetable composed of 162 time-indicating genes (182 probes) in the peripheral (liver) clock."} {"geneset":"CHESLER_BRAIN_HIGHEST_GENETIC_VARIANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHESLER_BRAIN_HIGHEST_GENETIC_VARIANCE","description":"Neurologically relevant transcripts with highest variance accounted for by mouse strain (genotype) differences."} {"geneset":"CHEN_LUNG_CANCER_SURVIVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_LUNG_CANCER_SURVIVAL","description":"Protein profiles associated with survival in lung adenocarcinoma."} {"geneset":"POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_UP","description":"Top up-regulated marker genes for medulloblastoma classification: desmoplastic vs classic morphology."} {"geneset":"WIELAND_UP_BY_HBV_INFECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIELAND_UP_BY_HBV_INFECTION","description":"Genes induced in the liver during hepatitis B (HBV) viral clearance in chimpanzees."} {"geneset":"SHEPARD_BMYB_MORPHOLINO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEPARD_BMYB_MORPHOLINO_UP","description":"Human orthologs of genes up-regulated in zebra fish after knockdown of BMYB [GeneID=4605] by morpholino."} {"geneset":"GOLUB_ALL_VS_AML_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLUB_ALL_VS_AML_DN","description":"Down-regulated genes highly correlated with acute lymphoblastic leukemia (ALL) vs acute myeloid leukemia (AML)."} {"geneset":"DISTECHE_ESCAPED_FROM_X_INACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DISTECHE_ESCAPED_FROM_X_INACTIVATION","description":"Genes that escape X inactivation."} {"geneset":"DER_IFN_BETA_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DER_IFN_BETA_RESPONSE_UP","description":"Genes up-regulated in HT1080 (fibrosarcoma) cells by treatment with interferon beta for 6 h."} {"geneset":"MANALO_HYPOXIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MANALO_HYPOXIA_DN","description":"Genes down-regulated in response to both hypoxia and overexpression of an active form of HIF1A [GeneID=3091]."} {"geneset":"CHESLER_BRAIN_HIGHEST_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHESLER_BRAIN_HIGHEST_EXPRESSION","description":"Neurologically relevant transcripts with highest abundance fold range in brain tissue among mouse strains."} {"geneset":"MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_DN","description":"Down-regulated genes discriminating multiple myeloma samples by type of immunoglobulin they produce: IgG vs IgA."} {"geneset":"LEE_LIVER_CANCER_MYC_E2F1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_MYC_E2F1_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) from MYC and E2F1 [GeneID=4609;1869] double transgenic mice."} {"geneset":"BYSTROEM_CORRELATED_WITH_IL5_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTROEM_CORRELATED_WITH_IL5_UP","description":"Genes whose expression in bone marrow samples correlated directly with increased levels of serum IL5 [GeneID=3567]."} {"geneset":"ZUCCHI_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZUCCHI_METASTASIS_UP","description":"The 50 most up-regulated genes in primary invasive breast dutcal carcinoma (IDC) or lymph node metastases, compared to normal mammary epithelium."} {"geneset":"CHESLER_BRAIN_D6MIT150_QTL_TRANS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHESLER_BRAIN_D6MIT150_QTL_TRANS","description":"Neurologically relevant genes modulated in brain tissue by a trans-regulatory QTL (quantitative trait locus) near D6Mit150 marker."} {"geneset":"NELSON_RESPONSE_TO_ANDROGEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NELSON_RESPONSE_TO_ANDROGEN_UP","description":"Genes up-regulated in LNCaP cells (prostate cancer) in response to synthetic androgen R1881 [PubChem=13766]."} {"geneset":"LIN_APC_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIN_APC_TARGETS","description":"Genes up-regulated by forced expression of APC [GeneID=324] in the APC-deficient SW480 cell line (colon cancer)."} {"geneset":"VANTVEER_BREAST_CANCER_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANTVEER_BREAST_CANCER_METASTASIS_DN","description":"Genes whose expression is significantly and negatively correlated with poor breast cancer clinical outcome (defined as developing distant metastases in less than 5 years)."} {"geneset":"BROCKE_APOPTOSIS_REVERSED_BY_IL6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROCKE_APOPTOSIS_REVERSED_BY_IL6","description":"Genes changed in INA-6 cells (multiple myeloma, MM) by re-addition of IL6 [GeneID=3569] after its initial withdrawal for 12h."} {"geneset":"POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN","description":"Top down-regulated marker genes for medulloblastoma classification: desmoplastic vs classic morphology."} {"geneset":"FRASOR_RESPONSE_TO_ESTRADIOL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRASOR_RESPONSE_TO_ESTRADIOL_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) by estradiol (E2) [PubChem=5757]."} {"geneset":"CHEOK_RESPONSE_TO_HD_MTX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEOK_RESPONSE_TO_HD_MTX_DN","description":"Genes specifically down-regulated in pediatric acute lymphoblastic leukemia (ALL) patients by high-dose methotrexate (HDMTX) [PubChem=4112]."} {"geneset":"TENEDINI_MEGAKARYOCYTE_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TENEDINI_MEGAKARYOCYTE_MARKERS","description":"Genes essential to the development of megakaryocytes, as expressed in normal cells and essential thrombocythemic cells (ET)."} {"geneset":"TARTE_PLASMA_CELL_VS_PLASMABLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TARTE_PLASMA_CELL_VS_PLASMABLAST_DN","description":"Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes."} {"geneset":"SMITH_LIVER_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMITH_LIVER_CANCER","description":"Potential marker genes specifically up-regulated in the majority of hepatocellular carcinoma (HCC) tumors."} {"geneset":"JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN","description":"Genes down-regulated during epithelial to mesenchymal transition (EMT) induced by TGFB1 [GeneID=7040] in the EpH4 cells (mammary epithelium cell line transformed by HRAS [GeneID=3265])."} {"geneset":"ROSS_AML_WITH_MLL_FUSIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROSS_AML_WITH_MLL_FUSIONS","description":"Top 100 probe sets for pediatric acute myeloid leukemia (AML) subtypes with chimeric MLL fusions [GeneID=4297]."} {"geneset":"GRANDVAUX_IRF3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRANDVAUX_IRF3_TARGETS_UP","description":"Genes up-regulated in Jurkat cells (T lymphocyte) by expression of a constitutively active form of IRF3 [GeneID=3661]."} {"geneset":"KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_UP","description":"Up-regulated genes predicting response of patients with hepatocellular carcinoma (HCC) to combination chemotherapy with 5-fluorouracil (5-FU) [PubChem=3385] and IFN1@ [GeneID=3438]."} {"geneset":"LEE_LIVER_CANCER_MYC_E2F1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_MYC_E2F1_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) from MYC and E2F1 [GeneID=4609;1869] double transgenic mice."} {"geneset":"ASTON_MAJOR_DEPRESSIVE_DISORDER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ASTON_MAJOR_DEPRESSIVE_DISORDER_UP","description":"Genes up-regulated in the temporal cortex samples from patients with major depressive disorder."} {"geneset":"LE_EGR2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LE_EGR2_TARGETS_UP","description":"Genes up-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [GeneID=1959]."} {"geneset":"FERNANDEZ_BOUND_BY_MYC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERNANDEZ_BOUND_BY_MYC","description":"Genes identified by ChIP within the high-affinity group of MYC [GeneID=4609] targets."} {"geneset":"FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP","description":"Genes upregulated in peripheral blood lymphocytes (PBL) from patients with well functioning kidneys more than 1-year post transplant compared to those from normal living kidney donors."} {"geneset":"ROSS_AML_OF_FAB_M7_TYPE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROSS_AML_OF_FAB_M7_TYPE","description":"Top 100 probe sets for pediatric acute myeloid leukemia (AML) subtype FAB M7 (also known as acute megakaryoblastic leukemia, AMKL)."} {"geneset":"MOOTHA_VOXPHOS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_VOXPHOS","description":"Genes involved in oxidative phosphorylation; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets."} {"geneset":"FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN","description":"Genes down-regulated in peripheral blood lymphocytes (PBL) from patients with acute transplant rejection compared to those from patients with well functioning kidneys more than 1-year post transplant."} {"geneset":"DER_IFN_GAMMA_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DER_IFN_GAMMA_RESPONSE_DN","description":"Genes down-regulated in HT1080 (fibrosarcoma) cells by treatment with interferon gamma for 6 h."} {"geneset":"SANA_RESPONSE_TO_IFNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANA_RESPONSE_TO_IFNG_UP","description":"Genes up-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by IFNG [GeneID=3458]."} {"geneset":"SANA_TNF_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANA_TNF_SIGNALING_UP","description":"Genes up-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by TNF [GeneID=7124]."} {"geneset":"POMEROY_MEDULLOBLASTOMA_PROGNOSIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POMEROY_MEDULLOBLASTOMA_PROGNOSIS_UP","description":"Top marker genes in medulloblastoma associated with good response to treatment (good outcome)."} {"geneset":"SCHUHMACHER_MYC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHUHMACHER_MYC_TARGETS_UP","description":"Genes up-regulated in P493-6 cells (Burkitt's lymphoma) induced to express MYC [GeneID=4609]."} {"geneset":"SWEET_KRAS_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SWEET_KRAS_TARGETS_UP","description":"Genes upregulated in KRAS [GeneID=3845] knockdown vs control in a human cell line."} {"geneset":"CHEOK_RESPONSE_TO_HD_MTX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEOK_RESPONSE_TO_HD_MTX_UP","description":"Genes specifically up-regulated in pediatric acute lymphoblastic leukemia (ALL) patients by high-dose methotrexate (HDMTX) [PubChem=4112]."} {"geneset":"MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_UP","description":"Up-regulated genes discriminating multiple myeloma samples by type of immunoglobulin they produce: IgG vs IgA."} {"geneset":"OKUMURA_INFLAMMATORY_RESPONSE_LPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OKUMURA_INFLAMMATORY_RESPONSE_LPS","description":"Genes up-regulated in mast cells (MC) after stimulation with a bacterial lipopolysaccharide (LPS)."} {"geneset":"SMITH_TERT_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMITH_TERT_TARGETS_DN","description":"Genes consistently down-regulated in HMEC cells (primary mammary epithelium) upon expression of TERT [GeneID=7015] off a retroviral vector."} {"geneset":"SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_DN","description":"Top 50 down-regulated markers distinguishing diffuse large B-cell lymphoma (DLBCL) from follicular lymphoma (FL) samples."} {"geneset":"LEE_LIVER_CANCER_DENA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_DENA_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) induced by diethylnitrosamine (DENA) [PubChem=5921]."} {"geneset":"SANA_RESPONSE_TO_IFNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANA_RESPONSE_TO_IFNG_DN","description":"Genes down-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by IFNG [GeneID=3458]."} {"geneset":"CHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_LD_MTX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_LD_MTX_DN","description":"Genes specifically down-regulated in pediatric acute lymphoblastic leukemia (ALL) patients by mercaptopurine [PubChem=667490] and low-dose methotrexate (LDMTX) [PubChem=4112]."} {"geneset":"LEE_LIVER_CANCER_MYC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_MYC_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) induced by overexpression of MYC [GeneID=4609]."} {"geneset":"LEE_LIVER_CANCER_CIPROFIBRATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_CIPROFIBRATE_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) induced by ciprofibrate [PubChem=2763]."} {"geneset":"IIZUKA_LIVER_CANCER_PROGRESSION_L1_G1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_PROGRESSION_L1_G1_UP","description":"Genes up-regulated during transition from L1 (non-tumor, infected with HCV) to G1 (well differentiated tumor, infected with HCV) in the development of hepatocellular carcinoma."} {"geneset":"POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN","description":"Top marker genes in medulloblastoma associated with poor response to treatment (poor outcome)."} {"geneset":"LU_IL4_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_IL4_SIGNALING","description":"Genes up-regulated in peripheral B lymphocytes after incubation with IL4 [GeneID=3565] for 4 h."} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS","description":"Transcripts in hematopoietic stem cells (HSC) which are trans-regulated (i.e., modulated by a QTL (quantitative trait locus) not in a close proximity to the gene)."} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_FLI1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_FLI1","description":"Genes whose expression is coregulated with that of FLI1 [GeneID=2313] in hematopoietic stem cells (HSC)."} {"geneset":"MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_DN","description":"Down-regulated genes discriminating multiple myeloma samples by the ype of immunoglobulin light chain they produce: Ig lambda (IGLL) vs Ig kappa (IGLK)."} {"geneset":"FERRANDO_LYL1_NEIGHBORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERRANDO_LYL1_NEIGHBORS","description":"Nearest neighbors of LYL1 [GeneID=4066], based on the close agreement of their expression profiles with that of LYL1 in pediatric T cell acute lymphoblastic leukemia (T-ALL)."} {"geneset":"PENG_GLUCOSE_DEPRIVATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PENG_GLUCOSE_DEPRIVATION_DN","description":"Genes down-regulated in BJAB cells (B-lymphoma) after glucose [PubChem=206] deprivation."} {"geneset":"VANTVEER_BREAST_CANCER_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANTVEER_BREAST_CANCER_METASTASIS_UP","description":"Genes whose expression is significantly and positively correlated with poor breast cancer clinical outcome (defined as developing distant metastases in less than 5 years)."} {"geneset":"COLLER_MYC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLLER_MYC_TARGETS_UP","description":"Genes up-regulated in 293T (transformed fetal renal cell) upon expression of MYC [GeneID=4609]."} {"geneset":"MANALO_HYPOXIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MANALO_HYPOXIA_UP","description":"Genes up-regulated in response to both hypoxia and overexpression of an active form of HIF1A [GeneID=3091]."} {"geneset":"REN_BOUND_BY_E2F","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REN_BOUND_BY_E2F","description":"Genes whose promoters were bound by E2F1 and E2F4 [GeneID=1869;1874] in the primary fibroblasts WI-38, by ChIP on chip assay."} {"geneset":"WONG_IFNA2_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_IFNA2_RESISTANCE_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) cell lines resistant to IFNA2 [GeneID=3440]."} {"geneset":"DORSAM_HOXA9_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORSAM_HOXA9_TARGETS_DN","description":"HOXA9 [GeneID=3205] targets down-regulated in hematopoietic stem cells."} {"geneset":"FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN","description":"Genes down-regulated in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant."} {"geneset":"YE_METASTATIC_LIVER_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YE_METASTATIC_LIVER_CANCER","description":"Genes up-regulated in hepatocellular carcinoma (HCC) with intra-hepatic metastasis compared to the non-metastatic tumors."} {"geneset":"SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP","description":"Top 50 up-regulated markers distinguishing diffuse large B-cell lymphoma (DLBCL) from follicular lymphoma (FL) samples."} {"geneset":"GRANDVAUX_IRF3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRANDVAUX_IRF3_TARGETS_DN","description":"Genes down-regulated in Jurkat cells (T lymphocyte) by expression of a constitutively active form of IRF3 [GeneID=3661]."} {"geneset":"IIZUKA_LIVER_CANCER_EARLY_RECURRENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IIZUKA_LIVER_CANCER_EARLY_RECURRENCE","description":"Genes down-regulated in hepatocellular carcinoma (HCC) tumors with higher risk of early intrahepatic recurrence. The single up-regulated gene (GenBank Accession=AC000063) has been excluded from the signature."} {"geneset":"RADAEVA_RESPONSE_TO_IFNA1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RADAEVA_RESPONSE_TO_IFNA1_DN","description":"Genes down-regulated in primary hepatocytes and Hep3B (hepatocyte) cells in response to IFNA [GeneID=3439]."} {"geneset":"BECKER_TAMOXIFEN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BECKER_TAMOXIFEN_RESISTANCE_DN","description":"Genes down-regulated in a breast cancer cell line resistant to tamoxifen [PubChem=5376] compared to the parental line sensitive to the drug."} {"geneset":"PEART_HDAC_PROLIFERATION_CLUSTER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEART_HDAC_PROLIFERATION_CLUSTER_DN","description":"Cell proliferation genes down-regulated by histone deacetylase (HDAC) inhibitors SAHA and depsipeptide [PubChem=5311;5352062]."} {"geneset":"NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP","description":"Up-regulated genes in lung tissue of smokers with chronic obstructive pulmonary disease (COPD) vs smokers without disease (GOLD-2 vs GOLD-0)."} {"geneset":"KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP","description":"Genes up-regulated in AIDS-related primary effusion lymphoma (PEL) samples compared to other tumor subtypes and normal B lymphocytes."} {"geneset":"SASAKI_ADULT_T_CELL_LEUKEMIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASAKI_ADULT_T_CELL_LEUKEMIA","description":"Genes up-regulated in adult T-cell leukemia (ATL) cells compared to T lymphocytes from healthy controls."} {"geneset":"PENG_RAPAMYCIN_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PENG_RAPAMYCIN_RESPONSE_DN","description":"Genes down-regulated in BJUB cells (B-lymphoma) in response to rapamycin (sirolimus) [PubChem=6610346] treatment."} {"geneset":"COLLER_MYC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLLER_MYC_TARGETS_DN","description":"Genes down-regulated in 293T (transformed fetal renal cell) upon expression of MYC [GeneID=4609]."} {"geneset":"LEE_LIVER_CANCER_E2F1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_E2F1_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) induced by overexpression of E2F1 [GeneID=1869]."} {"geneset":"LEE_LIVER_CANCER_DENA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_DENA_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) induced by diethylnitrosamine (DENA) [PubChem=5921]."} {"geneset":"FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN","description":"Genes down-regulated in kidney biopsies from patients with well functioning kidneys more than 1-year post transplant compared to the biopsies from normal living kidney donors."} {"geneset":"PENG_RAPAMYCIN_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PENG_RAPAMYCIN_RESPONSE_UP","description":"Genes up-regulated in BJUB cells (B-lymphoma) in response to rapamycin (sirolimus) [PubChem=6610346] treatment."} {"geneset":"PENG_GLUTAMINE_DEPRIVATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PENG_GLUTAMINE_DEPRIVATION_DN","description":"Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation."} {"geneset":"MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP","description":"Up-regulated genes discriminating multiple myeloma samples by the ype of immunoglobulin light chain they produce: Ig lambda (IGLL) vs Ig kappa (IGLK)."} {"geneset":"FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP","description":"Genes up-regulated in peripheral blood lymphocytes (PBL) from patients with acute transplant rejection compared to those from patients with well functioning kidneys more than 1-year post transplant."} {"geneset":"FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP","description":"Genes up-regulated in kidney biopsies from patients with well functioning kidneys more than 1-year post transplant compared to the biopsies from normal living kidney donors."} {"geneset":"GOLDRATH_IMMUNE_MEMORY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_IMMUNE_MEMORY","description":"'Memory genes' expressed uniquely in CD8+ [GeneID=925] memory T lymphocytes (compared with effector or naive cells)"} {"geneset":"LEE_LIVER_CANCER_E2F1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_E2F1_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) induced by overexpression of E2F1 [GeneID=1869]."} {"geneset":"ROSS_AML_WITH_AML1_ETO_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROSS_AML_WITH_AML1_ETO_FUSION","description":"Top 100 probe sets for pediatric acute myeloid leukemia (AML) subtype t(8;21) ; has AML1 ETO fusion [GeneID=861;862]."} {"geneset":"BHATTACHARYA_EMBRYONIC_STEM_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BHATTACHARYA_EMBRYONIC_STEM_CELL","description":"The 'stemnes' signature: genes up-regulated and common to 6 human embryonic stem cell lines tested."} {"geneset":"OSAWA_TNF_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OSAWA_TNF_TARGETS","description":"Genes up-regulated in Hc cells (normal hepatocyte) by TNF [GeneID=7124]."} {"geneset":"DER_IFN_GAMMA_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DER_IFN_GAMMA_RESPONSE_UP","description":"Genes up-regulated in HT1080 (fibrosarcoma) cells by treatment with interferon gamma for 6 h."} {"geneset":"HASLINGER_B_CLL_WITH_17P13_DELETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASLINGER_B_CLL_WITH_17P13_DELETION","description":"Genes changed in the B cell chronic lymphocytic leukemia (B-CLL) with deletions in the 17p13 region."} {"geneset":"YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP","description":"Genes up-regulated in the uteri of ovariectomized mice 6 h after progesterone [PubChem=5994] injection: HOXA10 [GeneID=3206] knockout vs wild type animals."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_CD1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_CD1_UP","description":"Top 50 up-regulated genes in cluster CD-1 of multiple myeloma samples with the characteristic expression spike of CCND1 [GeneID=595]."} {"geneset":"ABBUD_LIF_SIGNALING_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABBUD_LIF_SIGNALING_1_DN","description":"Genes down-regulated in AtT20 cells (pituitary cancer) after treatment with LIF [GeneID=3976]."} {"geneset":"SANSOM_APC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANSOM_APC_TARGETS_UP","description":"Top genes up-regulated at day 5 of Cre-Lox induced APC [GeneID=324] knockout in the intestine."} {"geneset":"NAKAJIMA_EOSINOPHIL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAJIMA_EOSINOPHIL","description":"Top 30 increased eosinophil specific transcripts."} {"geneset":"BROWN_MYELOID_CELL_DEVELOPMENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWN_MYELOID_CELL_DEVELOPMENT_UP","description":"Genes defining differentiation potential of the bipotential myeloid cell line FDB."} {"geneset":"NADLER_OBESITY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NADLER_OBESITY_UP","description":"Genes up-regulated in adipose tissue from obese mouse strains compared to the lean ones."} {"geneset":"SANSOM_APC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANSOM_APC_TARGETS_DN","description":"Top genes down-regulated at day 5 of Cre-Lox induced APC [GeneID=324] knockout in the intestine."} {"geneset":"ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN","description":"Selected genes changed in K562 (immortalized erythroleukemia) cells induced by hemin [PubChem=26945] treatment to express erythroid properties."} {"geneset":"ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION","description":"Genes up-regulated in RD-EF cells (rhabdomyosarcoma) engineered to express EWSR1-FLI1 fusion [GeneID=2130;2313] and which are also highly expressed in Ewing's famliy tumors."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_SUBGROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_SUBGROUPS","description":"Top genes up-regulated in MM4 vs MM1 subgroup of multiple myeloma samples."} {"geneset":"SCHURINGA_STAT5A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHURINGA_STAT5A_TARGETS_UP","description":"Genes up-regulated in hematopoietic stem cells (HSC) overexpressing a constitutively active form of STAT5 [GeneID=6776] off retroviral vector."} {"geneset":"HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP","description":"Genes up-regulated in hematopoietic progenitor cells (HPC) of T lymphocyte and NK (natural killer) lineage."} {"geneset":"MA_MYELOID_DIFFERENTIATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MA_MYELOID_DIFFERENTIATION_DN","description":"Genes down-regulated during myeloid differentiation induced by tretinoin (ATRA) [PubChem=444795] and IL3 [GeneID=3652] in the EML cell line (myeloid progenitor)."} {"geneset":"GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN","description":"Genes up-regulated in macrophages by aerolysin-related cytotoxic enterotoxin (Act) from Aeromonas hydrophila."} {"geneset":"VERNELL_RETINOBLASTOMA_PATHWAY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERNELL_RETINOBLASTOMA_PATHWAY_DN","description":"Cluster 2: genes down-regulated by RB1, CDNK2A [GeneID=1029;5925], and one of the E2Fs (E2F1, E2F2, or E2F3 [GeneID=1869;1870;1871])."} {"geneset":"HASLINGER_B_CLL_WITH_MUTATED_VH_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASLINGER_B_CLL_WITH_MUTATED_VH_GENES","description":"Genes changed in the B cell chronic lymphocytic leukemia (B-CLL) with mutations in the variable immunoglobulin veriable heavy chain (VH) genes."} {"geneset":"CROMER_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROMER_METASTASIS_UP","description":"Metastatic propensity markers of head and neck squamous cell carcinoma (HNSCC): up-regulated in metastatic vs non-metastatic tumors."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_DN","description":"Genes commonly down-regulated in CD-1 and CD-2 clusters of multiple myeloma samples and which were higher expressed in the CD-1 group."} {"geneset":"GUO_HEX_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUO_HEX_TARGETS_UP","description":"Genes up-regulated in day 6 embryoid bodies derived from embryonic stem cells (ES) with HEX [GeneID=3087] knockout."} {"geneset":"WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_DN","description":"Down-regulated genes in myeloid progenitors immortalized by HOXA9 [GeneID=3205] vs those immortalized by HOXA9 and MEIS1 [GeneID=4211]."} {"geneset":"ALCALAY_AML_BY_NPM1_LOCALIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALCALAY_AML_BY_NPM1_LOCALIZATION_UP","description":"Genes up-regulated in acute myeloid leukemia (AML) with respect to cellular localization of NPM1 [GeneID=4869]: cytoplasmic vs. nucleolar."} {"geneset":"FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP","description":"Genes up-regulated in B-CLL (B-cell chronic lymphocytic leukemia) patients with mutated immunoglobulin variable heavy chain (VH) genes."} {"geneset":"HEDVAT_ELF4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEDVAT_ELF4_TARGETS_UP","description":"Genes up-regulated in HEL cells (erythroleukemia) upon expression of ELF4 [GeneID=2000]."} {"geneset":"XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP","description":"Genes up-regulated synergistically in NB4 cells (acute promyelocytic leukemia, APL) by tretinoin and NSC682994 [PubChem=444795;388304]."} {"geneset":"STOSSI_RESPONSE_TO_ESTRADIOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STOSSI_RESPONSE_TO_ESTRADIOL","description":"Genes up-regulated by estradiol (E2) [PubChem=5757] in U2OS cells (osteosarcoma) expressing ESR1 or ESR2 [GeneID=2099;2100]."} {"geneset":"YU_MYC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YU_MYC_TARGETS_UP","description":"Genes up-regulated in B cell lymphoma tumors expressing an activated form of MYC [GeneID=4609]."} {"geneset":"MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN","description":"Genes down-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI [GeneID=23495]."} {"geneset":"ABBUD_LIF_SIGNALING_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABBUD_LIF_SIGNALING_2_UP","description":"Genes up-regulated in GH3 cells (pituitary cancer) after treatment with LIF [GeneID=3976]."} {"geneset":"PARK_HSC_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_HSC_MARKERS","description":"Genes in a cCDNA library from hematopoietic stem cells (HSC) after subtraction of lineage-specific markers."} {"geneset":"FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP","description":"Top 100 genes positively associated with T-cell acute lymphoblastic leukemia MLL T-ALL) expressing MLL-ENL fusion [GeneID=4297;4298]."} {"geneset":"HOFMANN_CELL_LYMPHOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFMANN_CELL_LYMPHOMA_DN","description":"Genes down-regulated in lymph nodes from patients with mantle cell lymphoma (MCL) compared to the non-malignant hyperplastic lymph nodes."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP","description":"Genes up-regulated in CD-1 compared to CD-2 cluster of multiple myeloma samples."} {"geneset":"MATSUDA_NATURAL_KILLER_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATSUDA_NATURAL_KILLER_DIFFERENTIATION","description":"Genes changed between developmental stages of Valpha14i natural killer T lymphocyte cells (NKT)."} {"geneset":"WANG_TARGETS_OF_MLL_CBP_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_TARGETS_OF_MLL_CBP_FUSION_UP","description":"Top 50 genes up-regulated in granulocyte/macrophage progenitors (GMP) upon expression of MLL-CBP fusion [GeneID=4297;1387]."} {"geneset":"STONER_ESOPHAGEAL_CARCINOGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STONER_ESOPHAGEAL_CARCINOGENESIS_UP","description":"Genes up-regulated in esophagus by the carcinogen NMBA [PubChem=13643] and brought back to normal by a diet with PEITC [PubChem=16741] or black raspberries."} {"geneset":"STONER_ESOPHAGEAL_CARCINOGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STONER_ESOPHAGEAL_CARCINOGENESIS_DN","description":"Genes down-regulated in esophagus by the carcinogen NMBA [PubChem=13643] and brought back to normal by a diet with PEITC [PubChem=16741] or black raspberries."} {"geneset":"HASLINGER_B_CLL_WITH_13Q14_DELETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASLINGER_B_CLL_WITH_13Q14_DELETION","description":"Genes changed in the B cell chronic lymphocytic leukemia (B-CLL) with deletions in the 13q14 region."} {"geneset":"HOFMANN_CELL_LYMPHOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFMANN_CELL_LYMPHOMA_UP","description":"Genes up-regulated in lymph nodes from patients with mantle cell lymphoma (MCL) compared to the non-malignant hyperplastic lymph nodes."} {"geneset":"GUO_HEX_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUO_HEX_TARGETS_DN","description":"Genes down-regulated in day 6 embryoid bodies derived from embryonic stem cells (ES) with HEX [GeneID=3087] knockout."} {"geneset":"HSIAO_LIVER_SPECIFIC_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HSIAO_LIVER_SPECIFIC_GENES","description":"Liver selective genes"} {"geneset":"GILDEA_METASTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GILDEA_METASTASIS","description":"Top genes down-regulated in metastatic (T24T) vs non-metastatic (T24) bladder cancer cell lines."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_SPIKED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_SPIKED","description":"'Spiked' genes: genes most highly up-regulated in multiple myeloma samples; were not differentially expressed as compared to the normal plasma cells."} {"geneset":"MUNSHI_MULTIPLE_MYELOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MUNSHI_MULTIPLE_MYELOMA_DN","description":"Genes down-regulated in multiple myeloma (MM) compared to normal plasma cells from the patient's identical twin."} {"geneset":"ASTIER_INTEGRIN_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ASTIER_INTEGRIN_SIGNALING","description":"Integrin signaling signature in precursor B leukemia (PBL) cells: fibronectin (FN1) [GeneID=2335] vs control treatment with poly-L-lysine."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_LB_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_LB_UP","description":"Top 50 up-regulated genes in cluster LB of multiple myeloma samples belonging to the low bone disease group."} {"geneset":"HASLINGER_B_CLL_WITH_11Q23_DELETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASLINGER_B_CLL_WITH_11Q23_DELETION","description":"Genes changed in the B cell chronic lymphocytic leukemia (B-CLL) with deletions in the 11q23 region."} {"geneset":"LEI_MYB_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEI_MYB_TARGETS","description":"Myb-regulated genes in MCF7 (breast cancer) and lung epithelial cell lines overexpressing MYBL2, MYBL1 or MYB [GeneID=4605;4603;4602]."} {"geneset":"BROWN_MYELOID_CELL_DEVELOPMENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWN_MYELOID_CELL_DEVELOPMENT_DN","description":"Genes defining proliferation and self renewal potential of the bipotential myeloid cell line FDB."} {"geneset":"ROETH_TERT_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROETH_TERT_TARGETS_DN","description":"Genes down-regulated in T lymphocytes overexpressing TERT [GeneID=7015] off a retrovirus vector."} {"geneset":"NEMETH_INFLAMMATORY_RESPONSE_LPS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NEMETH_INFLAMMATORY_RESPONSE_LPS_UP","description":"Genes up-regulated in RAW 264.7 cells (macrophage) 3 hr after stimulation with bacterial lipopolysaccharide (LPS)."} {"geneset":"LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN","description":"Genes down-regulated in Wilm's tumor samples compared to fetal kidney."} {"geneset":"HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN","description":"Genes down-regulated in hematopoietic precursor cells conditionally expressing HOXA9 and MEIS1 [GeneID=3205;4211]."} {"geneset":"HALMOS_CEBPA_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALMOS_CEBPA_TARGETS_DN","description":"Genes down-regulated in H358 cells (lung cancer) by inducible expression of CEBPA [GeneID=1050] off plasmid vector."} {"geneset":"NADLER_OBESITY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NADLER_OBESITY_DN","description":"Genes down-regulated in adipose tissue from obese mouse strains compared to the lean ones."} {"geneset":"FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN","description":"Top 100 genes negatively associated with T-cell acute lymphoblastic leukemia MLL T-ALL) expressing MLL-ENL fusion [GeneID=4297;4298]."} {"geneset":"WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP","description":"Up-regulated genes in myeloid progenitors immortalized by HOXA9 [GeneID=3205] vs those immortalized by HOXA9 and MEIS1 [GeneID=4211]."} {"geneset":"NEMETH_INFLAMMATORY_RESPONSE_LPS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NEMETH_INFLAMMATORY_RESPONSE_LPS_DN","description":"Genes down-regulated in RAW 264.7 cells (macrophage) 3 hr after stimulation with bacterial lipopolysaccharide (LPS)."} {"geneset":"GALE_APL_WITH_FLT3_MUTATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALE_APL_WITH_FLT3_MUTATED_DN","description":"Genes down-regulated in acute promyelocytic leukemia (APL) patients with mutated FLT3 [GeneID=2322]."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_UP","description":"Genes commonly up-regulated in CD-1 and CD-2 clusters of multiple myeloma samples and which were higher expressed in the CD-1 group."} {"geneset":"NADLER_HYPERGLYCEMIA_AT_OBESITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NADLER_HYPERGLYCEMIA_AT_OBESITY","description":"Genes correlated with the development of hyperglycemia in obese mice."} {"geneset":"RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP","description":"ES/PNET (Ewing sarcoma; primitive neuroectodermal tumors) markers up-regulated in neuroblastoma cell lines expressing ESWR1-FLI1 [GeneID=2130;2313] fusion protein."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_PR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_PR_UP","description":"Top 50 up-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes."} {"geneset":"HALMOS_CEBPA_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HALMOS_CEBPA_TARGETS_UP","description":"Genes up-regulated in H358 cells (lung cancer) by inducible expression of CEBPA [GeneID=1050] off plasmid vector."} {"geneset":"YU_MYC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YU_MYC_TARGETS_DN","description":"Genes down-regulated in B cell lymphoma tumors expressing an activated form of MYC [GeneID=4609]."} {"geneset":"NUMATA_CSF3_SIGNALING_VIA_STAT3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUMATA_CSF3_SIGNALING_VIA_STAT3","description":"Target genes for STAT3 [GeneID=20848] in CSF3 [GeneID=12985] signaling during myeloblast differentiation to neutrophils."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_UP","description":"Genes most significantly up-regulated in multiple myeloma samples, compared to normal bone marrow plasma cells."} {"geneset":"LENAOUR_DENDRITIC_CELL_MATURATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LENAOUR_DENDRITIC_CELL_MATURATION_UP","description":"Genes up-regulated during in vitro maturation of CD14+ [GeneID=929] monocytes (day 0) into immature (day 7) and mature dendritic cells (day 14)."} {"geneset":"TAVOR_CEBPA_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAVOR_CEBPA_TARGETS_DN","description":"Genes down-regulated in KCL22 cells (chronic myelogenous leukemia, CML, with BCR-ABL1 [GeneID=613;25] fusion) by expression of CEBPA [GeneID=1050]."} {"geneset":"LENAOUR_DENDRITIC_CELL_MATURATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LENAOUR_DENDRITIC_CELL_MATURATION_DN","description":"Genes down-regulated during in vitro maturation of CD14+ [GeneID=929] monocytes (day 0) into immature (day 7) and mature dendritic cells (day 14)."} {"geneset":"WANG_TARGETS_OF_MLL_CBP_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_TARGETS_OF_MLL_CBP_FUSION_DN","description":"Top 50 genes down-regulated in granulocyte/macrophage progenitors (GMP) upon expression of MLL-CBP fusion [GeneID=4297;1387]."} {"geneset":"HADDAD_B_LYMPHOCYTE_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HADDAD_B_LYMPHOCYTE_PROGENITOR","description":"Genes up-regulated in hematopoietic progenitor cells (HPC) of B lymphocyte lineage CD34+CD45RA+CD10+ [GeneID=947;5788;4311]."} {"geneset":"PARK_HSC_AND_MULTIPOTENT_PROGENITORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_HSC_AND_MULTIPOTENT_PROGENITORS","description":"Genes commonly expressed in long term hematopoietic stem cells (HSC) and multipotent progenitors (MPP)."} {"geneset":"GREENBAUM_E2A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GREENBAUM_E2A_TARGETS_DN","description":"Genes down-regulated in pre-B lymphocytes upon Cre-Lox knockout of E2A [GeneID=6929]."} {"geneset":"NGUYEN_NOTCH1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NGUYEN_NOTCH1_TARGETS_UP","description":"Genes up-regulated in primary keratinocytes by expression of constantly active NOTCH1 [GeneID=4851]."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_CD2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_CD2_UP","description":"Top 50 up-regulated genes in cluster CD-2 of multiple myeloma samples with the characteristic expression spike of CCND3 [GeneID=896]."} {"geneset":"HASLINGER_B_CLL_WITH_CHROMOSOME_12_TRISOMY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASLINGER_B_CLL_WITH_CHROMOSOME_12_TRISOMY","description":"Genes changed in the B cell chronic lymphocytic leukemia (B-CLL) with trisomy of chromosome 12."} {"geneset":"ABBUD_LIF_SIGNALING_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABBUD_LIF_SIGNALING_1_UP","description":"Genes up-regulated in AtT20 cells (pituitary cancer) after treatment with LIF [GeneID=3976]."} {"geneset":"ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP","description":"Genes up-regulated in immunoglobulin light chain amyloidosis plasma cells (ALPC) compared to multiple myeloma (MM) cells."} {"geneset":"THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP","description":"Genes up-regulated in polymorphonuclear neutrophilic granulocytes (PMNs) attracted to skin wounds."} {"geneset":"GERY_CEBP_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GERY_CEBP_TARGETS","description":"Genes changed in NIH 3T3 cells (embryonic fibroblast) by expression of one or more of C/EBP proteins: CEBPA, CEBPB, CEBPG, and CEBPD [GeneID=1050;1051;1054;1052]."} {"geneset":"VERHAAK_AML_WITH_NPM1_MUTATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERHAAK_AML_WITH_NPM1_MUTATED_UP","description":"Genes up-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [GeneID=4869]."} {"geneset":"KANG_IMMORTALIZED_BY_TERT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_IMMORTALIZED_BY_TERT_UP","description":"Up-regulated genes in the signature of adipose stromal cells (ADSC) immortalized by forced expression of telomerase (TERT) [GeneID=7015]."} {"geneset":"BASSO_CD40_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BASSO_CD40_SIGNALING_DN","description":"Gene down-regulated by CD40 [GeneID=958] signaling in Ramos cells (EBV negative Burkitt lymphoma)."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_MF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_MF_UP","description":"Top 50 up-regulated genes in cluster MF of multiple myeloma samples with characteristic expression spike of MAF family transcription factors."} {"geneset":"PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN","description":"Genes down-regulated in BEC (blood endothelial cells) compared to LEC (lymphatic endothelial cells)."} {"geneset":"JAIN_NFKB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAIN_NFKB_SIGNALING","description":"Genes abnormally regulated in response to CD40L and IL4 [GeneID=959;3565] stimulation of B lymphocytes from patients with a hypomorphic mutation of IKBKG [GeneID=8517]."} {"geneset":"ROETH_TERT_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROETH_TERT_TARGETS_UP","description":"Genes up-regulated in T lymphocytes overexpressing TERT [GeneID=7015] off a retrovirus vector."} {"geneset":"PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP","description":"Genes up-regulated in LEC (lymphatic endothelial cells) compared to BEC (blood endothelial cells)."} {"geneset":"LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP","description":"Genes up-regulated in Wilm's tumor samples compared to fetal kidney."} {"geneset":"STAEGE_EWING_FAMILY_TUMOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAEGE_EWING_FAMILY_TUMOR","description":"Genes up-regulated in Ewing family tumors (EFT) compared with normal bone marrow samples."} {"geneset":"GALE_APL_WITH_FLT3_MUTATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALE_APL_WITH_FLT3_MUTATED_UP","description":"Genes up-regulated in acute promyelocytic leukemia (APL) patients with mutated FLT3 [GeneID=2322]."} {"geneset":"AFFAR_YY1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AFFAR_YY1_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) expressing ~25% of YY1 [GeneID=7528]."} {"geneset":"THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN","description":"Genes down-regulated in polymorphonuclear neutrophilic granulocytes (PMNs) attracted to skin wounds."} {"geneset":"AFFAR_YY1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AFFAR_YY1_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) expressing ~25% of YY1 [GeneID=7528]."} {"geneset":"FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN","description":"Genes down-regulated in B-CLL (B-cell chronic lymphocytic leukemia) patients with mutated immunoglobulin variable heavy chain (VH) genes."} {"geneset":"VERNELL_RETINOBLASTOMA_PATHWAY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERNELL_RETINOBLASTOMA_PATHWAY_UP","description":"Cluster 1: genes up-regulated by RB1, CDNK2A [GeneID=1029;5925], and one of the E2Fs (E2F1, E2F2, or E2F3 [GeneID=1869;1870;1871])."} {"geneset":"ALCALAY_AML_BY_NPM1_LOCALIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALCALAY_AML_BY_NPM1_LOCALIZATION_DN","description":"Genes down-regulated in acute myeloid leukemia (AML) with respect to cellular localization of NPM1 [GeneID=4869]: cytoplasmic vs. nucleolar."} {"geneset":"KANG_IMMORTALIZED_BY_TERT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_IMMORTALIZED_BY_TERT_DN","description":"Down-regulated genes in the signature of adipose stromal cells (ADSC) immortalized by forced expression of telomerase (TERT) [GeneID=7015]."} {"geneset":"HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP","description":"Genes up-regulated in hematopoietic precursor cells conditionally expressing HOXA9 and MEIS1 [GeneID=3205;4211]."} {"geneset":"YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN","description":"Genes down-regulated in the uteri of ovariectomized mice 6 h after progesterone [PubChem=5994] injection: HOXA10 [GeneID=3206] knockout vs wild type animals."} {"geneset":"NGUYEN_NOTCH1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NGUYEN_NOTCH1_TARGETS_DN","description":"Genes down-regulated in primary keratinocytes by expression of constantly active NOTCH1 [GeneID=4851]."} {"geneset":"MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP","description":"Up-regulated genes distinguishing in multiple myeloma (MM) samples with higher expression of TACI [GeneID=23495]."} {"geneset":"CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70","description":"Differentially expressed genes between high vs low ZAP70 [GeneID=7535] acute lymphoblastic leukemia (ALL) cases with no known molecular aberrations."} {"geneset":"PETROVA_PROX1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETROVA_PROX1_TARGETS_DN","description":"Genes specific to BEC (blood endothelium cells) repressed in BEC by expression of PROX1 [GeneID=5629] off adenovirus vector."} {"geneset":"HOEGERKORP_CD44_TARGETS_DIRECT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOEGERKORP_CD44_TARGETS_DIRECT_DN","description":"Genes directly down-regulated by CD44 [GeneID=960] stimulation of B lymphocytes."} {"geneset":"BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS","description":"Genes significantly up-regulated in the blood mononuclear cells from patients with systemic lupus erythematosus compared to those from healthy persons."} {"geneset":"XU_RESPONSE_TO_TRETINOIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_RESPONSE_TO_TRETINOIN_UP","description":"Genes up-regulated in NB4 cells (acute promyelocytic leukemia, APL) by tretinoin [PubChem=444795] alone."} {"geneset":"ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN","description":"Genes down-regulated in immunoglobulin light chain amyloidosis plasma cells (ALPC) compared to multiple myeloma (MM) cells."} {"geneset":"MENSE_HYPOXIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MENSE_HYPOXIA_UP","description":"Hypoxia response genes up-regulated in both astrocytes and HeLa cell line."} {"geneset":"MARCINIAK_ER_STRESS_RESPONSE_VIA_CHOP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARCINIAK_ER_STRESS_RESPONSE_VIA_CHOP","description":"Endoplasmic retuculum (ER) stress response (caused by tunicamycin [PubChem=5282055]) genes dependent on CHOP [GeneID=13198]."} {"geneset":"ZHAN_V2_LATE_DIFFERENTIATION_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_V2_LATE_DIFFERENTIATION_GENES","description":"The v2LDG set: 50 most variable late differentiation genes (LDG) with similar expression patterns in bone marrow plasma cells (BPC) and multiple myeloma (MM) samples."} {"geneset":"DORSEY_GAB2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORSEY_GAB2_TARGETS","description":"Genes up-regulated by expression of GAB2 [GeneID=9846] in K562 cells (chronic myeloid leukemia (CML) cell line with p210 BCR-ABL [GeneID=613;25])."} {"geneset":"HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_DN","description":"Genes down-regulated in hematopoietic progenitor cells (HPC) of T lymphocyte and NK (natural killer) lineage."} {"geneset":"NAKAJIMA_MAST_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAJIMA_MAST_CELL","description":"Top 50 most-increased mast cell specific genes."} {"geneset":"LIAN_NEUTROPHIL_GRANULE_CONSTITUENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIAN_NEUTROPHIL_GRANULE_CONSTITUENTS","description":"Granule constituents expressed during mouse promyelocytic cell line differentiation to neutrophils."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_MS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_MS_UP","description":"Top 50 up-regulated genes in cluster MS of multiple myeloma samples with characteristic expression spike of WHSC1 [GeneID=7468]."} {"geneset":"MA_MYELOID_DIFFERENTIATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MA_MYELOID_DIFFERENTIATION_UP","description":"Genes up-regulated during myeloid differentiation induced by tretinoin (ATRA) [PubChem=444795] and IL3 [GeneID=3652] in the EML cell line (myeloid progenitor)."} {"geneset":"RADMACHER_AML_PROGNOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RADMACHER_AML_PROGNOSIS","description":"The 'Bullinger validation signature' [PMID=15084693] used to validate prediction of prognostic outcome of acute myeloid leukemia (AML) patients with a normal karyotype."} {"geneset":"CROMER_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROMER_METASTASIS_DN","description":"Metastatic propensity markers of head and neck squamous cell carcinoma (HNSCC): down-regulated in metastatic vs non-metastatic tumors."} {"geneset":"NOUZOVA_METHYLATED_IN_APL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOUZOVA_METHYLATED_IN_APL","description":"Genes whose CpG islands are hyper-methylated in the NB4 cell line (APL, acute promyelocytic leukemia) compared to PBMC (normal peripheral peripheral blood mononuclear cells)."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_HP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_HP_UP","description":"Top 50 up-regulated genes in cluster HP of multiple myeloma samples characterized by a hyperploid signature."} {"geneset":"XU_RESPONSE_TO_TRETINOIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_RESPONSE_TO_TRETINOIN_DN","description":"Genes down-regulated in NB4 cells (acute promyelocytic leukemia, APL) by tretinoin [PubChem=444795] alone."} {"geneset":"TAVOR_CEBPA_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAVOR_CEBPA_TARGETS_UP","description":"Genes up-regulated in KCL22 cells (chronic myelogenous leukemia, CML, with BCR-ABL1 [GeneID=613;25] fusion) by expression of CEBPA [GeneID=1050]."} {"geneset":"YAGI_AML_SURVIVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGI_AML_SURVIVAL","description":"Genes differentially expressed in pediatric AML (acute myeloid leukemia) samples from patients with good survival (>3 years without relapse) compared to those with poor survival (relapsed within one year after treatment)."} {"geneset":"XU_CREBBP_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_CREBBP_TARGETS_UP","description":"Genes up-regulated in pro-B lymphocytes after knockout of CREBBP [GeneID=1387]."} {"geneset":"VERHAAK_AML_WITH_NPM1_MUTATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERHAAK_AML_WITH_NPM1_MUTATED_DN","description":"Genes down-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [GeneID=4869]."} {"geneset":"RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN","description":"Neuroblastoma markers down-regulated in neuroblastoma cell lines expressing ESWR1-FLI1 [GeneID=2130;2313] fusion protein."} {"geneset":"APPEL_IMATINIB_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/APPEL_IMATINIB_RESPONSE","description":"Genes up-regulated by imatinib [PubChem=5291] during dendritic cell differentiation."} {"geneset":"YAGI_AML_FAB_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGI_AML_FAB_MARKERS","description":"Genes specifically expressed in FAB subtypes M2, M4, M5 and M7 of pediatric AML (acute myeloid leukemia)."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN","description":"Genes down-regulated in CD-1 compared to CD-2 cluster of multiple myeloma samples."} {"geneset":"MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN","description":"Down-regulated genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [GeneID=23495]."} {"geneset":"ABBUD_LIF_SIGNALING_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABBUD_LIF_SIGNALING_2_DN","description":"Genes down-regulated in GH3 cells (pituitary cancer) after treatment with LIF [GeneID=3976]."} {"geneset":"XU_CREBBP_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_CREBBP_TARGETS_DN","description":"Genes down-regulated in pro-B lymphocytes after knockout of CREBBP [GeneID=1387]."} {"geneset":"IGLESIAS_E2F_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IGLESIAS_E2F_TARGETS_DN","description":"Genes down-regulated in pancreatic cells from mice with double knockout of E2F1 [GeneID=1869] and E2F2 [GeneID=1870] compared to wild type."} {"geneset":"HOEGERKORP_CD44_TARGETS_TEMPORAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOEGERKORP_CD44_TARGETS_TEMPORAL_UP","description":"Genes temporally up-regulated by CD44 [GeneID=960] stimulation of B lymphocytes."} {"geneset":"SCHURINGA_STAT5A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHURINGA_STAT5A_TARGETS_DN","description":"Genes down-regulated in hematopoietic stem cells (HSC) overexpressing a constitutively active form of STAT5 [GeneID=6776] off retroviral vector."} {"geneset":"HOEGERKORP_CD44_TARGETS_TEMPORAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOEGERKORP_CD44_TARGETS_TEMPORAL_DN","description":"Genes temporally down-regulated by CD44 [GeneID=960] stimulation of B lymphocytes."} {"geneset":"IGLESIAS_E2F_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IGLESIAS_E2F_TARGETS_UP","description":"Genes up-regulated in pancreatic cells from mice with double knockout of E2F1 [GeneID=1869] and E2F2 [GeneID=1870] compared to wild type."} {"geneset":"MUNSHI_MULTIPLE_MYELOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MUNSHI_MULTIPLE_MYELOMA_UP","description":"Genes up-regulated in multiple myeloma (MM) compared to normal plasma cells from the patient's identical twin."} {"geneset":"KAMMINGA_EZH2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAMMINGA_EZH2_TARGETS","description":"Putative targets or partners of EZH2 [GeneID=2146] in hematopoietic stem cells."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_DN","description":"Genes most significantly down-regulated in multiple myeloma samples, compared to normal bone marrow plasma cells."} {"geneset":"BASSO_CD40_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BASSO_CD40_SIGNALING_UP","description":"Gene up-regulated by CD40 [GeneID=958] signaling in Ramos cells (EBV negative Burkitt lymphoma)."} {"geneset":"HASLINGER_B_CLL_WITH_6Q21_DELETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HASLINGER_B_CLL_WITH_6Q21_DELETION","description":"Genes changed in the B cell chronic lymphocytic leukemia (B-CLL) with deletions in the 6q21 region."} {"geneset":"HANSON_HRAS_SIGNALING_VIA_NFKB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HANSON_HRAS_SIGNALING_VIA_NFKB","description":"Genes changed by expression of activated form of HRas[GeneID=3265] in MEF cells (embryonic fibroblast) with or without p65/c-Rel complex [GeneID=5970;5966]."} {"geneset":"FAELT_B_CLL_WITH_VH3_21_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FAELT_B_CLL_WITH_VH3_21_DN","description":"Genes down-regulated in samples from B-CLL (B-cell chronic lymphocytic leukemia) with the immunoglobulin heavy chain VH3-21 gene."} {"geneset":"GREENBAUM_E2A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GREENBAUM_E2A_TARGETS_UP","description":"Genes up-regulated in pre-B lymphocytes upon Cre-Lox knockout of E2A [GeneID=6929]."} {"geneset":"XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_DN","description":"Genes down-regulated synergistically in NB4 cells (acute promyelocytic leukemia, APL) by tretinoin and NSC682994 [PubChem=444795;388304]."} {"geneset":"NOUZOVA_TRETINOIN_AND_H4_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOUZOVA_TRETINOIN_AND_H4_ACETYLATION","description":"Genes whose CpG islands showed greatly increased histone H4 acetylation in NB4 cells (acute promyelocytic leukemia, APL) upon treatment with tretinoin [PubChem=444795]."} {"geneset":"BRUNO_HEMATOPOIESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUNO_HEMATOPOIESIS","description":"Genes that are rapidly down-regulated as multipotential cells of the FDCP-mix hematopoiesis model undergo differentiation and loose their self-renewal and proliferation properties."} {"geneset":"MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP","description":"Genes up-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI (TNFRSF13B) [GeneID=23495]."} {"geneset":"PETROVA_PROX1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PETROVA_PROX1_TARGETS_UP","description":"Genes specific to LEC (lymphatic endothelium cells) induced in BEC (blood endothelium cells) by expression of PROX1 [GeneID=5629] off adenovirus vector."} {"geneset":"HOEGERKORP_CD44_TARGETS_DIRECT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOEGERKORP_CD44_TARGETS_DIRECT_UP","description":"Genes directly up-regulated by CD44 [GeneID=960] stimulation of B lymphocytes."} {"geneset":"KUMAR_TARGETS_OF_MLL_AF9_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUMAR_TARGETS_OF_MLL_AF9_FUSION","description":"Myeloid leukemia model in mice with germ-line MLL-AF9 fusion knock-in [GeneID=4297;4300]: genes changed in comparison among the leukemic, preleukemic and wild-type animals."} {"geneset":"FAELT_B_CLL_WITH_VH3_21_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FAELT_B_CLL_WITH_VH3_21_UP","description":"Genes up-regulated in samples from B-CLL (B-cell chronic lymphocytic leukemia) with the immunoglobulin heavy chain VH3-21 gene."} {"geneset":"SESTO_RESPONSE_TO_UV_C8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C8","description":"Cluster 8: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"KIM_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_HYPOXIA","description":"Genes up-regulated in normal fibroblasts under hypoxia conditions."} {"geneset":"GENTILE_UV_RESPONSE_CLUSTER_D9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_RESPONSE_CLUSTER_D9","description":"Cluster d9: genes progressively down-regulated in WS1 cells (fibroblast) through 24 h after irradiation with high dose UV-C."} {"geneset":"LIANG_SILENCED_BY_METHYLATION_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIANG_SILENCED_BY_METHYLATION_2","description":"Genes up-regulated in T24 cells (bladder carcinoma) after treatment with decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]."} {"geneset":"IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR","description":"Genes in the expression cluster 'Early Progenitors Shared': up-regulated in hematopoietic progenitors from adult bone marrow and from fetal liver."} {"geneset":"LY_AGING_PREMATURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LY_AGING_PREMATURE_DN","description":"Genes down-regulated in fibroblasts from patients with Hutchinson-Gilford progeria (premature aging), compared to those from normal young individuals."} {"geneset":"MARTINEZ_RESPONSE_TO_TRABECTEDIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_RESPONSE_TO_TRABECTEDIN","description":"Genes down-regulated by trabectedin [PubChem=3199] and its synthetic analog phthalascidin Pt 650 in HCT116 cells (colon cancer)."} {"geneset":"WEIGEL_OXIDATIVE_STRESS_BY_TBH_AND_H2O2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEIGEL_OXIDATIVE_STRESS_BY_TBH_AND_H2O2","description":"Oxidative stress genes down-regulated in ARPE-19 cells (retinal pigmented epithelium) in response to tert-butyl hydroperoxide (tBH) and H2O2 [PubChem=6410;784]."} {"geneset":"BROWNE_HCMV_INFECTION_20HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_20HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 20 h time point that were not up-regulated at the previous time point, 18 h."} {"geneset":"TAKAO_RESPONSE_TO_UVB_RADIATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKAO_RESPONSE_TO_UVB_RADIATION_UP","description":"Genes up-regulated in primary tissue culture of epidermal kerationcytes after UVB irradiation."} {"geneset":"URS_ADIPOCYTE_DIFFERENTIATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/URS_ADIPOCYTE_DIFFERENTIATION_UP","description":"Genes up-regulated in primary adipocytes compared to preadipocytes."} {"geneset":"LEE_AGING_NEOCORTEX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_AGING_NEOCORTEX_DN","description":"Downregulated in the neocortex of aged adult mice (30-month) vs young adult (5-month)"} {"geneset":"REN_ALVEOLAR_RHABDOMYOSARCOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REN_ALVEOLAR_RHABDOMYOSARCOMA_UP","description":"Genes commonly up-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion."} {"geneset":"REN_ALVEOLAR_RHABDOMYOSARCOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REN_ALVEOLAR_RHABDOMYOSARCOMA_DN","description":"Genes commonly down-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion."} {"geneset":"TRAYNOR_RETT_SYNDROM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TRAYNOR_RETT_SYNDROM_UP","description":"Genes up-regulated in primary fibroblasts from Rett syndrom patients who carry mutations inactivating MECP2 [GeneID=4204]."} {"geneset":"MCCLUNG_DELTA_FOSB_TARGETS_8WK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCLUNG_DELTA_FOSB_TARGETS_8WK","description":"Genes up-regulated in the nucleus accumbens (a major reward center in brain) 8 weeks after induction of deltaFosB, a FOSB [GeneID=2354] splice variant."} {"geneset":"BRACHAT_RESPONSE_TO_METHOTREXATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRACHAT_RESPONSE_TO_METHOTREXATE_DN","description":"Genes down-regulated in FL5.12 cells (pro-B lymphocyte) in response to methotrexate [PubChem=4112]."} {"geneset":"BROWNE_HCMV_INFECTION_16HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_16HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 16 h time point that were not up-regulated at the previous time point, 14 h."} {"geneset":"MODY_HIPPOCAMPUS_POSTNATAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODY_HIPPOCAMPUS_POSTNATAL","description":"Genes up-regulated in hyppocampus at late postnatal stages (clusters 11 and 15)."} {"geneset":"IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS","description":"Genes up-regulated in MCF-7 cells (breast cancer) in response to growth medium from L3T3-L1 cells (differentiated to pre-adipocytes)."} {"geneset":"JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN","description":"Down-regulated genes distinguishing between breast cancer tumors with mutated BRCA1 [GeneID=672] from those with mutated BRCA2 [GeneID=675]."} {"geneset":"BURTON_ADIPOGENESIS_10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_10","description":"Strongly down-regulated at 8-48 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"ABE_VEGFA_TARGETS_2HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABE_VEGFA_TARGETS_2HR","description":"Genes up-regulated in HUVEC cells (endothelium) at 2 h after VEGFA [GeneID=7422] stimulation."} {"geneset":"SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1A","description":"Genes basally silent, with hypermethylated promoters, up-regulated by the combination of TSA and decitabine [PubChem=5562;451668] in RKO cells (colorectal cancer)."} {"geneset":"NATSUME_RESPONSE_TO_INTERFERON_BETA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NATSUME_RESPONSE_TO_INTERFERON_BETA_UP","description":"Genes up-regulated in T98 cells (glioma) 48 h after treatment with interferon beta."} {"geneset":"BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP","description":"Genes up-regulated in patients at the incipient stage of Alzheimer's disease."} {"geneset":"IVANOVA_HEMATOPOIESIS_MATURE_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVA_HEMATOPOIESIS_MATURE_CELL","description":"Genes in the expression cluster 'MBC Shared': up-regulated in mature blood cell populations from adult bone marrow and fetal liver."} {"geneset":"DAZARD_UV_RESPONSE_CLUSTER_G3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G3","description":"Cluster G3: genes increasingly up-regulated in NHEK cells (normal keratinocyte) after 6 h time point upon UV-B irradiation."} {"geneset":"SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_UP","description":"Up-regulated in murine dorsal skin cells at 6 h after treatment with the phorbol ester carcinogen TPA [PubChem=4792]."} {"geneset":"WEBER_METHYLATED_IN_COLON_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_IN_COLON_CANCER","description":"Genes identified as hypermethylated in SW48 cells (colon cancer)."} {"geneset":"KAAB_FAILED_HEART_ATRIUM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAAB_FAILED_HEART_ATRIUM_DN","description":"Genes down-regulated in atria of failing hearts (DCM and ICM) compared to healthy controls."} {"geneset":"SU_PANCREAS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SU_PANCREAS","description":"Genes up-regulated specifically in human pancreas."} {"geneset":"RUAN_RESPONSE_TO_TROGLITAZONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUAN_RESPONSE_TO_TROGLITAZONE_UP","description":"Adipocyte abundant genes up-regulated in 3T3-L1 cells (fibroblasts induced to differentiate to adipocytes) in response to troglitazone [PubChem=5591]."} {"geneset":"WU_HBX_TARGETS_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_HBX_TARGETS_2_DN","description":"Genes down-regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] in primary hepatocytes."} {"geneset":"ZAMORA_NOS2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZAMORA_NOS2_TARGETS_UP","description":"Up-regulated in hepatocytes upon expression of NOS2 [GeneID=4843]."} {"geneset":"JIANG_AGING_CEREBRAL_CORTEX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_AGING_CEREBRAL_CORTEX_UP","description":"Up-regulated in the cerebral cortex of aged (22 months) BALB/c mice, compared to young (2 months) controls"} {"geneset":"WEIGEL_OXIDATIVE_STRESS_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEIGEL_OXIDATIVE_STRESS_RESPONSE","description":"Oxidative stress genes down-regulated in ARPE-19 cells (retinal pigmented epithelium) in response to HNE, tBH and H2O2 [PubChem=5283344;6410;784]."} {"geneset":"HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC","description":"Genes distinguishing between sporadic breast cancer tumors and hereditary breast cancer tumors that have mutated BRCA1 and BRCA2 [GeneID=672;675]."} {"geneset":"DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP","description":"Genes up-regulated in HEK293 cells (embryonic kidney) at 6 h, 12 h or 24 h after infection with reovirus strain T3A (known as a strong inducer of apoptosis)."} {"geneset":"BRACHAT_RESPONSE_TO_CISPLATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRACHAT_RESPONSE_TO_CISPLATIN","description":"Genes up-regulated in FL5.12 cells (pro-B lymphocyte) in response to cisplatin [PubChem=2767]."} {"geneset":"IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR","description":"Genes in the expression cluster 'Late Progenitors Shared': up-regulated in hematopoietic late progenitor cells from adult bone marrow and fetal liver."} {"geneset":"LU_AGING_BRAIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_AGING_BRAIN_DN","description":"Age down-regulated genes in the human frontal cortex."} {"geneset":"RUAN_RESPONSE_TO_TNF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUAN_RESPONSE_TO_TNF_UP","description":"Adipocyte abundant genes up-regulated in 3T3-L1 cells (fibroblasts induced to differentiate to adipocytes) in response to TNF [GeneID=7124]."} {"geneset":"WHITESIDE_CISPLATIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITESIDE_CISPLATIN_RESISTANCE_UP","description":"Genes up-regulated in NCI-H2170 cells (lung cancer) upon induction of resistance to cisplatin [PubChem=2767]."} {"geneset":"LEE_CALORIE_RESTRICTION_NEOCORTEX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_CALORIE_RESTRICTION_NEOCORTEX_UP","description":"Up-regulated in the neocortex of aged (30-month) mice subjected to caloric restriction since young adulthood."} {"geneset":"JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN","description":"Genes down-regulated in H460 cells (non-small cell lung carcinoma, NSCLC) after treatment with sodium butyrate [PubChem=5222465]."} {"geneset":"IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM","description":"Genes in the expression cluster 'LT-HSC Shared': up-regulated in long term hematopoietic stem cells (LT-HSC) from adult bone marrow and fetal liver."} {"geneset":"WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_H2O2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_H2O2","description":"Oxidative stress genes down-regulated in ARPE-19 cells (retinal pigmented epithelium) in response to HNE and H2O2 [PubChem=5283344;784]."} {"geneset":"HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_4HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_4HR","description":"Genes discriminating between direct (cisplatin, MMS, mitomycin C [PubChem=2767;4156;5746]) and indirect (paclitaxel, hydroxyurea, etoposide [PubChem=4666;3657;36462]) acting genotoxins at 4 h time point."} {"geneset":"ZHOU_TNF_SIGNALING_4HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_TNF_SIGNALING_4HR","description":"Genes up-regulated in HeLa cells (cervical carcinoma) at 4 h after stimulation with TNF [GeneID=7124]."} {"geneset":"MARCHINI_TRABECTEDIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARCHINI_TRABECTEDIN_RESISTANCE_UP","description":"Genes up-regulated in chondrosarcoma and ovarian carcinoma cell lines which developed resistance to trabectedin [PubChem=3199]."} {"geneset":"GENTILE_UV_LOW_DOSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_LOW_DOSE_UP","description":"Selected genes up-regulated in WS1 (fibroblast) in response to irradiation with low dose UV-C."} {"geneset":"BLALOCK_ALZHEIMERS_DISEASE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BLALOCK_ALZHEIMERS_DISEASE_DN","description":"Genes down-regulated in brain from patients with Alzheimer's disease."} {"geneset":"BROWNE_HCMV_INFECTION_16HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_16HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 16 h time point that were not down-regulated at the previous time point, 14 h."} {"geneset":"WESTON_VEGFA_TARGETS_6HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WESTON_VEGFA_TARGETS_6HR","description":"Genes up-regulated in MMEC cells (myometrial endothelium) at 6 h after VEGFA [GeneID=7422] stimulation."} {"geneset":"BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_24HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_24HR_UP","description":"Genes up-regulated in A172 cells (glioma, does not express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 24 h."} {"geneset":"RAMALHO_STEMNESS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMALHO_STEMNESS_DN","description":"Genes depleted in embryonic, neural and hematopoietic stem cells."} {"geneset":"ONGUSAHA_TP53_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONGUSAHA_TP53_TARGETS","description":"Genes up-regulated in MEF cells (embryonic fibroblast) lacking TP53 and BRCA1 [GeneID=7157;672] by expression of TP53; most genes are further up-regulated by simultaneous expression of BRCA1."} {"geneset":"GENTILE_UV_RESPONSE_CLUSTER_D4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_RESPONSE_CLUSTER_D4","description":"Cluster d4: genes progressively down-regulated in WS1 cells (fibroblast) through 12 h after irradiation with high dose UV-C."} {"geneset":"RHODES_CANCER_META_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RHODES_CANCER_META_SIGNATURE","description":"Genes commonly up-regulated in cancer relative to normal tissue, according to the meta-analysis of the OncoMine gene expression database."} {"geneset":"NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP","description":"Top 20 positive significant genes associated with malignant fibrous histiocytoma tumors."} {"geneset":"LIAN_LIPA_TARGETS_6M","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIAN_LIPA_TARGETS_6M","description":"Genes up-regulated at 6 months of age in lungs from LIPA [GeneID=3988] knockout mice, which display pulmonary pathology."} {"geneset":"WU_HBX_TARGETS_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_HBX_TARGETS_1_DN","description":"Genes down-regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] in SK-Hep-1 cells (hepatocellular carcinoma)."} {"geneset":"NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_DN","description":"Top 20 genes whose down-regulation correlated with gastrointestinal stromal tumors (GIST) and synovial sarcoma compared to other tumors."} {"geneset":"HARRIS_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HARRIS_HYPOXIA","description":"Genes known to be induced by hypoxia"} {"geneset":"RUAN_RESPONSE_TO_TNF_TROGLITAZONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUAN_RESPONSE_TO_TNF_TROGLITAZONE_DN","description":"Adipocyte abundant genes down-regulated in 3T3-L1 cells (fibroblasts induced to differentiate to adipocytes) in response to troglitazone [PubChem=5591] and TNF [GeneID=7124]."} {"geneset":"SU_SALIVARY_GLAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SU_SALIVARY_GLAND","description":"Genes up-regulated specifically in human salivary gland tissue."} {"geneset":"BROWNE_HCMV_INFECTION_10HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_10HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 10 h time point that were not down-regulated at the previous time point, 8 h."} {"geneset":"KAYO_CALORIE_RESTRICTION_MUSCLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAYO_CALORIE_RESTRICTION_MUSCLE_DN","description":"Downregulated in the vastus lateralis muscle of middle aged rhesus monkeys subjected to caloric restriction since young adulthood vs age matched controls"} {"geneset":"HENDRICKS_SMARCA4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HENDRICKS_SMARCA4_TARGETS_UP","description":"Genes up-regulated in ALAB cells (breast cancer) upon reintroduction of SMARCA4 [GeneID=6597] expressed off adenoviral vector."} {"geneset":"ZHENG_RESPONSE_TO_ARSENITE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_RESPONSE_TO_ARSENITE_DN","description":"Down-regulated in HEK293 cells (kidney epithelium) by treatment with sodium arsenite [PubChem=26435]."} {"geneset":"MURAKAMI_UV_RESPONSE_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MURAKAMI_UV_RESPONSE_6HR_DN","description":"Genes down-regulated in primary keratinocytes at 6 h after UVB irradiation."} {"geneset":"CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN","description":"Down-regulated genesin the left ventricle myocardium of patients with heart failure following implantation of LVAD (left ventricular assist device)."} {"geneset":"RAMALHO_STEMNESS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMALHO_STEMNESS_UP","description":"Genes enriched in embryonic, neural and hematopoietic stem cells."} {"geneset":"MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_7","description":"Cluster 7: genes up-regulated in SW260 cells (colon cancer) by curcumin and sulindac [PubChem=969516;5352]."} {"geneset":"MCDOWELL_ACUTE_LUNG_INJURY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCDOWELL_ACUTE_LUNG_INJURY_UP","description":"Genes up-regulated in the mouse model of acute lung injury induced by inhaling nickel sulfate [PubChem=24586]."} {"geneset":"SESTO_RESPONSE_TO_UV_C4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C4","description":"Cluster 4: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"WANG_SMARCE1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_SMARCE1_TARGETS_DN","description":"Genes down-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector."} {"geneset":"SU_TESTIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SU_TESTIS","description":"Genes up-regulated specifically in human testis tissue."} {"geneset":"TRAYNOR_RETT_SYNDROM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TRAYNOR_RETT_SYNDROM_DN","description":"Genes down-regulated in primary fibroblasts from Rett syndrom patients who carry mutations inactivating MECP2 [GeneID=4204]."} {"geneset":"SESTO_RESPONSE_TO_UV_C6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C6","description":"Cluster 6: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"MCCLUNG_CREB1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCLUNG_CREB1_TARGETS_DN","description":"Genes down-regulated in the nucleus accumbens (a major reward center in the brain) 8 weeks after induction of CREB1 [GeneID=1385] expression in a transgenic Tet-Off system."} {"geneset":"RODWELL_AGING_KIDNEY_NO_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODWELL_AGING_KIDNEY_NO_BLOOD_DN","description":"Genes whose expression decreases with age in normal kidney, excluding those with higher expression in blood."} {"geneset":"INGRAM_SHH_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/INGRAM_SHH_TARGETS","description":"Genes up-regulated by in C3H/10T1/2 cells (embryonic pluripotent cell) in response to SSH [GeneID=6469]."} {"geneset":"SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1B","description":"Genes with some basal expression and partially methylated promoters, up-regulated by the combination of TSA and decitabine [PubChem=5562;451668] in RKO cells (colorectal cancer)."} {"geneset":"SESTO_RESPONSE_TO_UV_C2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C2","description":"Cluster 2: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"KAAB_HEART_ATRIUM_VS_VENTRICLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAAB_HEART_ATRIUM_VS_VENTRICLE_UP","description":"Genes up-regulated in the atria of healthy hearts, compared to venticles."} {"geneset":"HU_GENOTOXIC_DAMAGE_24HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HU_GENOTOXIC_DAMAGE_24HR","description":"Genes most consistently regulated at 24 h by all six genotoxins tested: cisplatin, methyl methanesulfonate, mitomycin C, taxol, hydroxyurea and etoposide [PubChem=2767;4156;5746;4666;3657;36462]."} {"geneset":"NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_UP","description":"Top 20 genes whose up-regulation correlated with gastrointestinal stromal tumors (GIST) compared to synovial sarcoma."} {"geneset":"CUI_TCF21_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CUI_TCF21_TARGETS_UP","description":"Genes most strongly up-regulated in kidney glomeruli isolated from TCF21 [GeneID=6943] knockout mice."} {"geneset":"HEDENFALK_BREAST_CANCER_BRACX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEDENFALK_BREAST_CANCER_BRACX_UP","description":"Up-regulated genes distinguishing between two groups of non-BRCA1/BRCA2 [GeneID=672;675] breast tumors (BRACx): group A vs group B."} {"geneset":"GEISS_RESPONSE_TO_DSRNA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GEISS_RESPONSE_TO_DSRNA_DN","description":"Genes down-pregulated by dsRNA in GRE cells (glioma; no interferon system)."} {"geneset":"CUI_TCF21_TARGETS_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CUI_TCF21_TARGETS_2_DN","description":"All significantly down-regulated genes in kidney glomeruli isolated from TCF21 [Gene ID=6943] knockout mice."} {"geneset":"VIETOR_IFRD1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VIETOR_IFRD1_TARGETS","description":"Genes down-regulated in c-JunER cells (mammary gland epithelum) by overexpression of IFRD1 [GeneID=3475] off an adenovirus vector."} {"geneset":"PAL_PRMT5_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAL_PRMT5_TARGETS_UP","description":"Genes up-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [GeneID=10419] by RNAi."} {"geneset":"VARELA_ZMPSTE24_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VARELA_ZMPSTE24_TARGETS_DN","description":"Top genes down-regulated in liver tissue from mice with knockout of ZMPSTE24 [GeneID=10269]."} {"geneset":"SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2","description":"50 most interesting genes up-regulated in the pancreatic cancer cell lines (AsPC1, Hs766T, MiaPaCa2, Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]."} {"geneset":"ZHANG_RESPONSE_TO_CANTHARIDIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_RESPONSE_TO_CANTHARIDIN_UP","description":"Genes up-regulated in HL-60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]."} {"geneset":"HEDENFALK_BREAST_CANCER_BRACX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEDENFALK_BREAST_CANCER_BRACX_DN","description":"Down-regulated genes distinguishing between two groups of non-BRCA1/BRCA2 [GeneID=672;675] breast tumors (BRACx): group A vs group B."} {"geneset":"JIANG_AGING_HYPOTHALAMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_AGING_HYPOTHALAMUS_DN","description":"Down-regulated in the hypothalamus of aged (22 months) BALB/c mice, compared to young (2 months) controls"} {"geneset":"CHANG_IMMORTALIZED_BY_HPV31_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANG_IMMORTALIZED_BY_HPV31_DN","description":"Genes down-regulated in normal keratinocytes immortalized by infection with the high risk HPV31 (human papilloma virus) strain."} {"geneset":"BROWNE_HCMV_INFECTION_24HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_24HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 24 h time point that were not down-regulated at the previous time point, 20 h."} {"geneset":"MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_8","description":"Cluster 8: genes down-regulated in SW260 cells (colon cancer) by sodium butyrate, curcumin, sulindac and TSA [PubChem=5222465;969516;5352;5562]."} {"geneset":"CHIBA_RESPONSE_TO_TSA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIBA_RESPONSE_TO_TSA_UP","description":"Cancer related genes up-regulated in any of four hepatoma cell lines following 24 h treatment with TSA [PubChem=5562]."} {"geneset":"RAMASWAMY_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMASWAMY_METASTASIS_DN","description":"Down-regulated genes in metastatic vs primary solid tumors."} {"geneset":"MODY_HIPPOCAMPUS_NEONATAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODY_HIPPOCAMPUS_NEONATAL","description":"Genes highly expressed in the neonatal hippocampus (clusters 4 and 8)."} {"geneset":"MCCLUNG_COCAINE_REWARD_5D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCLUNG_COCAINE_REWARD_5D","description":"Genes up-regulated in the nucleus accumbens (a major reward center in the brain) after 5 days of cocaine [PubChem=5760] treatment."} {"geneset":"KAYO_AGING_MUSCLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAYO_AGING_MUSCLE_UP","description":"Upregulated in the vastus lateralis muscle of aged vs young adult rhesus monkeys"} {"geneset":"VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_UP","description":"Genes up-regulated after heat shock in peripheral lympocytes from old donors, compared to those from the young ones."} {"geneset":"CHUANG_OXIDATIVE_STRESS_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHUANG_OXIDATIVE_STRESS_RESPONSE_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) after treatment with the oxydants: hydrogen peroxyde, menadione, and t-butyl hydroperoxyde [PubChem=784;4055;6410]."} {"geneset":"BROWNE_HCMV_INFECTION_14HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_14HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not down-regulated at the previous time point, 12 h."} {"geneset":"DELASERNA_MYOD_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELASERNA_MYOD_TARGETS_DN","description":"Genes down-regulated in NIH 3T3 cells (fibroblasts) 24 h after inducing MyoD [GeneID=4654] differentiation program."} {"geneset":"YAMAZAKI_TCEB3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMAZAKI_TCEB3_TARGETS_UP","description":"Genes up-regulated in embryonic stem cells from TCEB3 [GeneID=6924] knockout mice."} {"geneset":"HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR","description":"Genes discriminating between direct (cisplatin, MMS, mitomycin C [PubChem=2767;4156;5746]) and indirect (paclitaxel, hydroxyurea, etoposide [PubChem=4666;3657;36462]) acting genotoxins at 24 h time point."} {"geneset":"JIANG_VHL_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_VHL_TARGETS","description":"Genes up-regulated in 786-0 cells (renal carcinoma, RCC) upon expression of VHL [GeneID=7428] off a retroviral vector under normoxia (normal oxygen) condition."} {"geneset":"MACLACHLAN_BRCA1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MACLACHLAN_BRCA1_TARGETS_DN","description":"Genes down-regulated in SW480 cells (colon cancer with mutated p53 [GeneID=7157]) upon expression of BRCA1 [GeneID=672] off an adenovirus vector."} {"geneset":"LEE_AGING_CEREBELLUM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_AGING_CEREBELLUM_DN","description":"Downregulated in the cerebellum of aged adult mice (30-month) vs young adult (5-month)"} {"geneset":"EHRLICH_ICF_SYNDROM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EHRLICH_ICF_SYNDROM_UP","description":"Up-regulated in B lymphocytes from patients with ICF syndrom caused by mutations in DNMT3B [GeneID=1789] compared to normals."} {"geneset":"BROWNE_INTERFERON_RESPONSIVE_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_INTERFERON_RESPONSIVE_GENES","description":"Genes up-regulated in primary fibroblast culture after treatment with interferon alpha for 6 h."} {"geneset":"MCCLUNG_DELTA_FOSB_TARGETS_2WK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCLUNG_DELTA_FOSB_TARGETS_2WK","description":"Genes up-regulated in the nucleus accumbens (a major reward center in brain) 2 weeks after induction of deltaFosB, a FOSB [GeneID=2354] splice variant."} {"geneset":"CUI_TCF21_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CUI_TCF21_TARGETS_DN","description":"Genes most strongly down-regulated in kidney glomeruli isolated from TCF21 [GeneID=6943] knockout mice."} {"geneset":"SU_THYMUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SU_THYMUS","description":"Genes up-regulated specifically in human thymus."} {"geneset":"KANG_FLUOROURACIL_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_FLUOROURACIL_RESISTANCE_DN","description":"Genes down-regulated in gastric cancer cell lines resistant to 5-fluorouracil [PubChem=3385]."} {"geneset":"NIELSEN_LIPOSARCOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_LIPOSARCOMA_DN","description":"Top 20 negative significant genes associated with liposarcomas, versus other soft-tissue tumors."} {"geneset":"BROWNE_HCMV_INFECTION_8HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_8HR_UP","description":"Genes up-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 8 h time point that were not up-regulated at the previous time point, 6 h."} {"geneset":"MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP","description":"Genes up-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]."} {"geneset":"JI_RESPONSE_TO_FSH_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JI_RESPONSE_TO_FSH_DN","description":"Down-regulated in ovarian epithelial cells (MCV152) 72 hours following FSH treatment, compared to untreated"} {"geneset":"WESTON_VEGFA_TARGETS_12HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WESTON_VEGFA_TARGETS_12HR","description":"Genes up-regulated in MMEC cells (myometrial endothelium) at 12 h after VEGFA [GeneID=7422] stimulation."} {"geneset":"KRASNOSELSKAYA_ILF3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRASNOSELSKAYA_ILF3_TARGETS_UP","description":"Up-regulated in GHOST(3)CXCR4 cells (osteosarcoma) upon ectopic expression of ILF3 [GeneID=3609]."} {"geneset":"CHUANG_OXIDATIVE_STRESS_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHUANG_OXIDATIVE_STRESS_RESPONSE_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) after treatment with the oxydants: hydrogen peroxyde, menadione, and t-butyl hydroperoxyde [PubChem=784;4055;6410]."} {"geneset":"KEEN_RESPONSE_TO_ROSIGLITAZONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEEN_RESPONSE_TO_ROSIGLITAZONE_UP","description":"Genes up-regulated in aorta biopsies from mice treated with rosiglitazone [PubChem=77999]."} {"geneset":"NATSUME_RESPONSE_TO_INTERFERON_BETA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NATSUME_RESPONSE_TO_INTERFERON_BETA_DN","description":"Genes down-regulated in T98 cells (glioma) 48 h after treatment with interferon beta."} {"geneset":"BAELDE_DIABETIC_NEPHROPATHY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAELDE_DIABETIC_NEPHROPATHY_UP","description":"Genes up-regulated in glomeruli of kidneys from patients with diabetic nephropathy (type 2 diabetes mellitus)."} {"geneset":"LINDVALL_IMMORTALIZED_BY_TERT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDVALL_IMMORTALIZED_BY_TERT_UP","description":"Genes up-regulated in BJ cells (foreskin fibroblasts) immortalized by expression of TERT [GeneID=7015]."} {"geneset":"WU_HBX_TARGETS_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_HBX_TARGETS_3_UP","description":"Genes up-regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] both in SK-Hep-1 cells (hepatocellular carcinoma) and normal primary hepatocytes."} {"geneset":"WANG_CISPLATIN_RESPONSE_AND_XPC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_CISPLATIN_RESPONSE_AND_XPC_DN","description":"Genes down-regulated in fibroblasts with defective XPC [GeneID=7508] in response to cisplatin [PubChem=2767]."} {"geneset":"MURAKAMI_UV_RESPONSE_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MURAKAMI_UV_RESPONSE_6HR_UP","description":"Genes up-regulated in primary keratinocytes at 6 h after UVB irradiation."} {"geneset":"BROWNE_HCMV_INFECTION_20HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_20HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 20 h time point that were not down-regulated at the previous time point, 18 h."} {"geneset":"SIMBULAN_PARP1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIMBULAN_PARP1_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblasts) from PARP1 [GeneID=142] knockout mice."} {"geneset":"ULE_SPLICING_VIA_NOVA2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ULE_SPLICING_VIA_NOVA2","description":"Genes whose splicing in neocortex was most affected by knock out of NOVA2 [GeneID=4858]."} {"geneset":"MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_DN","description":"Cluster 10: genes down-regulated in SW260 cells (colon cancer) by sodium butyrate and TSA [PubChem=5222465;5562] with the same kinetics with which each alters the level of histone H4 acetylation."} {"geneset":"IVANOVA_HEMATOPOIESIS_STEM_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVA_HEMATOPOIESIS_STEM_CELL","description":"Genes in the expression cluster 'HSC Shared': up-regulated in hematopoietic stem cells (HSC) from adult bone marrow and fetal liver."} {"geneset":"KUNINGER_IGF1_VS_PDGFB_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUNINGER_IGF1_VS_PDGFB_TARGETS_DN","description":"Genes down-regulated in C2AS12 cells (myoblast) by IGF1 [GeneID=3479] vs PDGFB [GeneID=5155]."} {"geneset":"MEDINA_SMARCA4_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEDINA_SMARCA4_TARGETS","description":"Genes up-regulated in H1299 cells (lung cancer) by expression of SMARCA4 [GeneID=6597] off a plasmid vector."} {"geneset":"KANG_FLUOROURACIL_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_FLUOROURACIL_RESISTANCE_UP","description":"Genes up-regulated in gastric cancer cell lines resistant to 5-fluorouracil [PubChem=3385]."} {"geneset":"MAHAJAN_RESPONSE_TO_IL1A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAHAJAN_RESPONSE_TO_IL1A_DN","description":"Genes down-regulated in corneal fibroblasts after treatment with IL1A [GeneID=3552]."} {"geneset":"RUAN_RESPONSE_TO_TNF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUAN_RESPONSE_TO_TNF_DN","description":"Adipocyte abundant genes down-regulated in 3T3-L1 cells (fibroblasts induced to differentiate to adipocytes) in response to TNF [GeneID=7124]."} {"geneset":"BLALOCK_ALZHEIMERS_DISEASE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BLALOCK_ALZHEIMERS_DISEASE_UP","description":"Genes up-regulated in brain from patients with Alzheimer's disease."} {"geneset":"DELASERNA_MYOD_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELASERNA_MYOD_TARGETS_UP","description":"Genes up-regulated in NIH 3T3 cells (fibroblasts) 24 h after inducing MyoD [GeneID=4654] differentiation program."} {"geneset":"BURTON_ADIPOGENESIS_12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_12","description":"Strongly down-regulated at 2 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"LEONARD_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEONARD_HYPOXIA","description":"Genes up-regulated in HK-2 cells kidney tubular epithelium) under hypoxia and down-regulated on re-oxygenation."} {"geneset":"KAYO_AGING_MUSCLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAYO_AGING_MUSCLE_DN","description":"Downregulated in the vastus lateralis muscle of aged vs young adult rhesus monkeys"} {"geneset":"KAAB_FAILED_HEART_ATRIUM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAAB_FAILED_HEART_ATRIUM_UP","description":"Genes up-regulated in atria of failing hearts (DCM and ICM) compared to healthy controls."} {"geneset":"NIELSEN_LIPOSARCOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_LIPOSARCOMA_UP","description":"Top 20 positive significant genes associated with liposarcomas, versus other soft-tissue tumors."} {"geneset":"INGA_TP53_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/INGA_TP53_TARGETS","description":"Genes whose promoters contain TP53 [GeneID=7157] response elements."} {"geneset":"MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP","description":"Cluster 9: genes up-regulated in SW260 cells (colon cancer) by sodium butyrate and TSA [PubChem=5222465;5562] with the same kinetics with which each alters the level of histone H4 acetylation."} {"geneset":"DASU_IL6_SIGNALING_SCAR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DASU_IL6_SIGNALING_SCAR_UP","description":"Genes up-regulated in hypertrophic scar fibroblasts in response to IL6 [GeneID=3569]."} {"geneset":"LINDVALL_IMMORTALIZED_BY_TERT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDVALL_IMMORTALIZED_BY_TERT_DN","description":"Genes down-regulated in BJ cells (foreskin fibroblasts) immortalized by expression of TERT [GeneID=7015]."} {"geneset":"DAZARD_RESPONSE_TO_UV_SCC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_RESPONSE_TO_UV_SCC_DN","description":"Genes down-regulated in SCC12B2 cells (squamous cell carcinoma) by UV-B irradiation."} {"geneset":"CHIBA_RESPONSE_TO_TSA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIBA_RESPONSE_TO_TSA","description":"Genes up-regulated in more than one of several human hepatoma cell lines by TSA [PubChem=5562]."} {"geneset":"RODWELL_AGING_KIDNEY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODWELL_AGING_KIDNEY_DN","description":"Genes whose expression decreases with age in normal kidney."} {"geneset":"YIH_RESPONSE_TO_ARSENITE_C2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YIH_RESPONSE_TO_ARSENITE_C2","description":"Genes in cluster 2: moderately up-regulated in HFW cells (fibroblast) upon treatment with sodium arsenite [PubChem=26435] at all time points."} {"geneset":"KANG_DOXORUBICIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_DOXORUBICIN_RESISTANCE_UP","description":"Genes up-regulated in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive."} {"geneset":"BROWNE_HCMV_INFECTION_48HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_48HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 48 h time point that were not down-regulated at the previous time point, 24 h."} {"geneset":"BROWNE_HCMV_INFECTION_48HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_48HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 48 h time point that were not up-regulated at the previous time point, 24 h."} {"geneset":"MA_PITUITARY_FETAL_VS_ADULT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MA_PITUITARY_FETAL_VS_ADULT_DN","description":"Down-regulated in human fetal pituitary tissue, compared to adult pituitary tissue"} {"geneset":"BURTON_ADIPOGENESIS_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_5","description":"Up-regulated at 48-96 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"WESTON_VEGFA_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WESTON_VEGFA_TARGETS","description":"Genes up-regulated in MMEC cells (myometrial endothelium) by VEGFA [GeneID=7422] stimulation."} {"geneset":"CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP","description":"Up-regulated genesin the left ventricle myocardium of patients with heart failure following implantation of LVAD (left ventricular assist device)."} {"geneset":"BROWNE_HCMV_INFECTION_8HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_8HR_DN","description":"Genes down-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 8 h time point that were not down-regulated at the previous time point, 6 h."} {"geneset":"APRELIKOVA_BRCA1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/APRELIKOVA_BRCA1_TARGETS","description":"Genes down-regulated in embryonic stem cells with BRCA1 [GeneID=672] loss of function (LOF)."} {"geneset":"VERRECCHIA_RESPONSE_TO_TGFB1_C2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERRECCHIA_RESPONSE_TO_TGFB1_C2","description":"Cluster 2: ECM related genes up-regulated in dermal fibroblasts within 30 min after TGFB1 [GeneID=7040] addition; reached a plateau after that."} {"geneset":"KIM_GASTRIC_CANCER_CHEMOSENSITIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_GASTRIC_CANCER_CHEMOSENSITIVITY","description":"Genes up-regulated in gastric cancer patients refractory to chemotherapy treatment with 5-fluorouracil and cisplatin [PubChem=3385;2767] compared to the sensitive state."} {"geneset":"BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_24HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_24HR_DN","description":"Genes down-regulated in T98G cells (glioma, express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 24 h."} {"geneset":"GENTILE_UV_RESPONSE_CLUSTER_D5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_RESPONSE_CLUSTER_D5","description":"Cluster d5: genes progressively down-regulated in WS1 cells (fibroblast) through 18 h after irradiation with high dose UV-C."} {"geneset":"BRACHAT_RESPONSE_TO_METHOTREXATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRACHAT_RESPONSE_TO_METHOTREXATE_UP","description":"Genes up-regulated in FL5.12 cells (pro-B lymphocyte) in response to methotrexate [PubChem=4112]."} {"geneset":"RHODES_UNDIFFERENTIATED_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RHODES_UNDIFFERENTIATED_CANCER","description":"Genes commonly up-regulated in undifferentiated cancer relative to well-differentiated cancer, based on the meta-analysis of the OncoMine gene expression database."} {"geneset":"BROWNE_HCMV_INFECTION_14HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_14HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not up-regulated at the previous time point, 12 h."} {"geneset":"YAMAZAKI_TCEB3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMAZAKI_TCEB3_TARGETS_DN","description":"Genes down-regulated in embryonic stem cells from TCEB3 [GeneID=6924] knockout mice."} {"geneset":"LEE_CALORIE_RESTRICTION_MUSCLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_CALORIE_RESTRICTION_MUSCLE_UP","description":"Up-regulated in the gastrocnemius muscle of aged (30-month) mice subjected to caloric restriction diet since young adulthood."} {"geneset":"MACLACHLAN_BRCA1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MACLACHLAN_BRCA1_TARGETS_UP","description":"Genes up-regulated in SW480 cells (colon cancer with mutated p53 [GeneID=7157]) upon expression of BRCA1 [GeneID=672] off an adenovirus vector."} {"geneset":"VERRECCHIA_RESPONSE_TO_TGFB1_C1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERRECCHIA_RESPONSE_TO_TGFB1_C1","description":"Cluster 1: ECM related genes up-regulated in dermal fibroblasts within 30 min after TGFB1 [GeneID=7040] addition, and which kept increasing with time."} {"geneset":"GAJATE_RESPONSE_TO_TRABECTEDIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAJATE_RESPONSE_TO_TRABECTEDIN_DN","description":"Genes down-regulated in HeLa cells (cervical carcinoma) by trabectedin [PubChem=3199]."} {"geneset":"LEE_AGING_MUSCLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_AGING_MUSCLE_DN","description":"Downregulated in the gastrocnemius muscle of aged adult mice (30-month) vs young adult (5-month)"} {"geneset":"ZHANG_PROLIFERATING_VS_QUIESCENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_PROLIFERATING_VS_QUIESCENT","description":"Genes up-regulated in HDMEC cells (microvascular endothelium): proliferating vs quiescent cells."} {"geneset":"GAJATE_RESPONSE_TO_TRABECTEDIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAJATE_RESPONSE_TO_TRABECTEDIN_UP","description":"Genes up-regulated in HeLa cells (cervical carcinoma) by trabectedin [PubChem=3199]."} {"geneset":"VERRECCHIA_RESPONSE_TO_TGFB1_C5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERRECCHIA_RESPONSE_TO_TGFB1_C5","description":"Cluster 5: ECM related genes up-regulated in dermal fibroblasts later than 30 min after TGFB1 [GeneID=7040] addition; decreased slowly after the peak at 120 min time point."} {"geneset":"GERHOLD_ADIPOGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GERHOLD_ADIPOGENESIS_DN","description":"Selected genes down-regulated during differentiation of 3T3-L1 cells (fibroblast) into adipocytes in response to adipogenic hormones."} {"geneset":"LU_AGING_BRAIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_AGING_BRAIN_UP","description":"Age up-regulated genes in the human frontal cortex."} {"geneset":"BURTON_ADIPOGENESIS_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_3","description":"Strongly up-regulated at 16-24 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"DAZARD_RESPONSE_TO_UV_NHEK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_RESPONSE_TO_UV_NHEK_UP","description":"Genes up-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation."} {"geneset":"LIAN_LIPA_TARGETS_3M","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIAN_LIPA_TARGETS_3M","description":"Genes up-regulated at 3 months of age in lungs from LIPA [GeneID=3988] knockout mice, which display pulmonary pathology."} {"geneset":"ZHU_CMV_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHU_CMV_ALL_UP","description":"Up-regulated at any timepoint following infection of primary human foreskin fibroblasts with CMV"} {"geneset":"MA_PITUITARY_FETAL_VS_ADULT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MA_PITUITARY_FETAL_VS_ADULT_UP","description":"Up-regulated in human fetal pituitary tissue, compared to adult pituitary tissue"} {"geneset":"BURTON_ADIPOGENESIS_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_8","description":"Progressively down-regulated 8-96 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"DELLA_RESPONSE_TO_TSA_AND_BUTYRATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELLA_RESPONSE_TO_TSA_AND_BUTYRATE","description":"Genes up-regulated in HT-29 cells (colon cancer) by the combination of trichostatin A (TSA) and sodium butyrate [PubChem=5562;5222465]."} {"geneset":"RUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP","description":"Adipocyte abundant genes up-regulated in 3T3-L1 cells (fibroblasts induced to differentiate to adipocytes) in response to troglitazone [PubChem=5591] and TNF [GeneID=7124]."} {"geneset":"BURTON_ADIPOGENESIS_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_2","description":"Strongly up-regulated at 8 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"VERRECCHIA_EARLY_RESPONSE_TO_TGFB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERRECCHIA_EARLY_RESPONSE_TO_TGFB1","description":"ECM related genes up-regulated early (within 30 min) in dermal fibroblasts after addition of TGFB1 [GeneID=7040]."} {"geneset":"XU_GH1_EXOGENOUS_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_GH1_EXOGENOUS_TARGETS_UP","description":"Genes up-regulated in MFCF-7 cells (breast cancer) by exogenous HG1 [GeneID=2688]."} {"geneset":"ZHU_CMV_8_HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHU_CMV_8_HR_DN","description":"Down-regulated at 8 h following infection of primary human foreskin fibroblasts with CMV"} {"geneset":"ZHU_CMV_24_HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHU_CMV_24_HR_DN","description":"Down-regulated at 24 h following infection of primary human foreskin fibroblasts with CMV"} {"geneset":"WU_HBX_TARGETS_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_HBX_TARGETS_3_DN","description":"Genes down-regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] both in SK-Hep-1 cells (hepatocellular carcinoma) and normal primary hepatocytes."} {"geneset":"SU_KIDNEY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SU_KIDNEY","description":"Genes up-regulated specifically in human kidney tissue."} {"geneset":"GENTILE_UV_RESPONSE_CLUSTER_D2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_RESPONSE_CLUSTER_D2","description":"Cluster d2: genes down-regulated consistently in WS1 cells (fibroblast) between 6 h and 24 h after irradiation with high dose UV-C."} {"geneset":"PAL_PRMT5_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAL_PRMT5_TARGETS_DN","description":"Genes down-regulated in NIH-3T3 cells (fibroblast) after knockdown of PRMT5 [GeneID=10419] by RNAi."} {"geneset":"VISALA_AGING_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VISALA_AGING_LYMPHOCYTE_DN","description":"Genes down-regulated in peripheral lymphocytes from old individuals compared to those from young donors."} {"geneset":"SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER","description":"50 genes up-regulated in the pancreatic cancer cell lines (AsPC1, Hs766T, MiaPaCa2, Panc1) but not in the non-neoplastic cells (HPDE) by the combination of decitabine and TSA [PubChem=451668;5562]."} {"geneset":"CHEN_ETV5_TARGETS_SERTOLI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_ETV5_TARGETS_SERTOLI","description":"Genes down-regulated in Sertoli cells from both 4 and 10 week old ETV5 [GeneID=2119] knockout mice."} {"geneset":"BROWNE_HCMV_INFECTION_18HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_18HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 18 h time point that were not down-regulated at the previous time point, 16 h."} {"geneset":"MOREIRA_RESPONSE_TO_TSA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOREIRA_RESPONSE_TO_TSA_UP","description":"Up-regulated in CD4+ [GeneID=920] T lymphocytes after 4 h treatment with 100 nM TSA [PubChem=5562]."} {"geneset":"IVANOVA_HEMATOPOIESIS_STEM_CELL_SHORT_TERM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVA_HEMATOPOIESIS_STEM_CELL_SHORT_TERM","description":"Genes in the expression cluster 'ST-HSC Shared': up-regulated in short term hematopoietic stem cells (ST-HSC) from adult bone marrow and fetal liver."} {"geneset":"TAKAO_RESPONSE_TO_UVB_RADIATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAKAO_RESPONSE_TO_UVB_RADIATION_DN","description":"Genes down-regulated in primary tissue culture of epidermal kerationcytes after UVB irradiation."} {"geneset":"YIH_RESPONSE_TO_ARSENITE_C4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YIH_RESPONSE_TO_ARSENITE_C4","description":"Genes in cluster 4: immediate down-regulation in HFW cells (fibroblast) by sodium arsenite [PubChem=26435]."} {"geneset":"ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP","description":"Genes up-regulated in A549 cells (lung carcinoma) upon infection with RSV (respiratory syncytial virus) and up-regulated by further treatment with ribavirin [PubChem=5064]."} {"geneset":"MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_4","description":"Cluster 4: genes down-regulated in SW260 cells (colon cancer) by sodium butyrate and sulindac [PubChem=5222465;5352]."} {"geneset":"ZHENG_RESPONSE_TO_ARSENITE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_RESPONSE_TO_ARSENITE_UP","description":"Up-regulated in HEK293 cells (kidney epithelium) by treatment with sodium arsenite [PubChem=26435]."} {"geneset":"DAZARD_UV_RESPONSE_CLUSTER_G4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G4","description":"Cluster G4: genes increasingly up-regulated in NHEK cells (normal keratinocyte) after 12 h time point after UV-B irradiation."} {"geneset":"GENTILE_UV_RESPONSE_CLUSTER_D7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_RESPONSE_CLUSTER_D7","description":"Cluster d7: genes progressively down-regulated in WS1 cells (fibroblast) through 18 h after irradiation with high dose UV-C."} {"geneset":"EHRLICH_ICF_SYNDROM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EHRLICH_ICF_SYNDROM_DN","description":"Down-regulated in B lymphocytes from patients with ICF syndrom caused by mutations in DNMT3B [GeneID=1789] compared to normals."} {"geneset":"KAAB_HEART_ATRIUM_VS_VENTRICLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAAB_HEART_ATRIUM_VS_VENTRICLE_DN","description":"Genes down-regulated in the ventricles of healthy hearts, compared to atria."} {"geneset":"GENTILE_UV_RESPONSE_CLUSTER_D6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_RESPONSE_CLUSTER_D6","description":"Cluster d6: genes progressively down-regulated in WS1 cells (fibroblast) through 18 h after irradiation with high dose UV-C."} {"geneset":"VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1","description":"ECM related genes up-regulated later than 30 min following addition of TGFB1 [GeneID=7040] in dermal fibroblasts."} {"geneset":"BROWNE_HCMV_INFECTION_18HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_18HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 18 h time point that were not up-regulated at the previous time point, 16 h."} {"geneset":"LEE_AGING_NEOCORTEX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_AGING_NEOCORTEX_UP","description":"Upregulated in the neocortex of aged adult mice (30-month) vs young adult (5-month)"} {"geneset":"ZHANG_RESPONSE_TO_CANTHARIDIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_RESPONSE_TO_CANTHARIDIN_DN","description":"Genes down-regulated in HL-60 cells (promyeloid leukemia) by cantharidin [PubChem=6708701]."} {"geneset":"BURTON_ADIPOGENESIS_PEAK_AT_24HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_PEAK_AT_24HR","description":"Cluster 5: genes progressively up-regulated (peak at 24 h time point) during differentiation of 3T3-L1 fibroblasts into adipocytes in response to adipogenic hormones."} {"geneset":"SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP","description":"Genes up-regulated in 3T3-L1 cells (adipocyte) by insulin [GeneID=3630] which continued to respond normally to insulin in the insulin resistant cells."} {"geneset":"MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_UP","description":"Genes similarly up-regulated in 3T3-L1 cells (fibroblasts able to differentiate to adipocytes) upon stimulation of INSR or IGFR1 by NTF3 [GeneID=3643;3480;4908]."} {"geneset":"BRACHAT_RESPONSE_TO_CAMPTOTHECIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRACHAT_RESPONSE_TO_CAMPTOTHECIN_UP","description":"Genes specifically up-regulated in FL5.12 cells (pro-B lymphocyte) by camptothecin [PubChem=2538]."} {"geneset":"GENTILE_UV_HIGH_DOSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_HIGH_DOSE_DN","description":"Selected genes down-regulated in WS1 (fibroblast) in response to irradiation with high dose UV-C."} {"geneset":"GEORGANTAS_HSC_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GEORGANTAS_HSC_MARKERS","description":"Genes up-regulated in HSC (hematopoietic stem cells) compared to HPC (hematopoietic progenitor cells)."} {"geneset":"HENDRICKS_SMARCA4_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HENDRICKS_SMARCA4_TARGETS_DN","description":"Genes down-regulated in ALAB cells (breast cancer) upon reintroduction of SMARCA4 [GeneID=6597] expressed off adenoviral vector."} {"geneset":"HAN_JNK_SINGALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAN_JNK_SINGALING_UP","description":"Genes up-regulated in 3T3 cells (fibroblast) upon activation of JNK pathway."} {"geneset":"KANG_DOXORUBICIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_DOXORUBICIN_RESISTANCE_DN","description":"Genes down-regulated in gastric cancer cell lines: doxorubicin [PubChem=31703] resistant vs sensitive."} {"geneset":"SESTO_RESPONSE_TO_UV_C0","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C0","description":"Cluster 0: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"MCLACHLAN_DENTAL_CARIES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCLACHLAN_DENTAL_CARIES_DN","description":"Genes down-regulated in pulpal tissue extracted from carious teeth."} {"geneset":"BURTON_ADIPOGENESIS_PEAK_AT_2HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_PEAK_AT_2HR","description":"Cluster 2: genes maximally expressed at 2 h time point during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 2) in response to adipogenic hormones."} {"geneset":"CHEN_PDGF_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_PDGF_TARGETS","description":"Up-regulated PDGF targets identified by a gene-trap screen."} {"geneset":"MCCLUNG_CREB1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCLUNG_CREB1_TARGETS_UP","description":"Genes up-regulated in the nucleus accumbens (a major reward center in the brain) 8 weeks after induction of CREB1 [GeneID=1385] expression in a transgenic Tet-Off system."} {"geneset":"LEE_AGING_CEREBELLUM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_AGING_CEREBELLUM_UP","description":"Upregulated in the cerebellum of aged adult mice (30-month) vs young adult (5-month)"} {"geneset":"WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_TBH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_TBH","description":"Oxidative stress genes down-regulated in ARPE-19 cells (retinal pigmented epithelium) in response to HNE and tBH [PubChem=5283344;6410]."} {"geneset":"TSENG_IRS1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSENG_IRS1_TARGETS_DN","description":"Down-regulated in brown preadipocytes with IRS1 [GeneID=3667] knockout vs wild type controls; the knockouts have severe defects in adipocyte differentiation."} {"geneset":"RODWELL_AGING_KIDNEY_NO_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODWELL_AGING_KIDNEY_NO_BLOOD_UP","description":"Genes whose expression increases with age in normal kidney, excluding those with higher expression in blood."} {"geneset":"RODWELL_AGING_KIDNEY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RODWELL_AGING_KIDNEY_UP","description":"Genes whose expression increases with age in normal kidney."} {"geneset":"MCCLUNG_COCAIN_REWARD_4WK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCLUNG_COCAIN_REWARD_4WK","description":"Genes up-regulated in the nucleus accumbens (a major reward center in the brain) after 4 weeks of cocaine [PubChem=5760] treatment."} {"geneset":"ZHOU_TNF_SIGNALING_30MIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_TNF_SIGNALING_30MIN","description":"Genes up-regulated in HeLa cells (cervical carcinoma) at 30 min after stimulation with TNF [GeneID=7124]."} {"geneset":"WELCSH_BRCA1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WELCSH_BRCA1_TARGETS_UP","description":"Up-regulated by induction of exogenous BRCA1 in EcR-293 cells"} {"geneset":"JACKSON_DNMT1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JACKSON_DNMT1_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) upon Cre-lox knockout of DNMT1 [GeneID=1786]."} {"geneset":"CHANG_IMMORTALIZED_BY_HPV31_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANG_IMMORTALIZED_BY_HPV31_UP","description":"Genes up-regulated in normal keratinocytes immortalized by infection with the high risk HPV31 (human papilloma virus) strain."} {"geneset":"MODY_HIPPOCAMPUS_PRENATAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODY_HIPPOCAMPUS_PRENATAL","description":"Genes highly expressed in prenatal hippocampus (cluster 1)."} {"geneset":"BURTON_ADIPOGENESIS_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_4","description":"Progressively up-regulated from 8-48 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"ZHU_CMV_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHU_CMV_ALL_DN","description":"Down-regulated at any timepoint following infection of primary human foreskin fibroblasts with CMV"} {"geneset":"IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR","description":"Genes in the expression cluster 'Intermediate Progenitors Shared': up-regulated in hematopoietic intemediate progenitor cells from adult bone marrow and fetal liver."} {"geneset":"GENTILE_UV_HIGH_DOSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_HIGH_DOSE_UP","description":"Selected genes up-regulated in WS1 (fibroblast) in response to irradiation with high dose UV-C."} {"geneset":"SU_LIVER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SU_LIVER","description":"Genes up-regulated specifically in human liver tissue."} {"geneset":"CHIBA_RESPONSE_TO_TSA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIBA_RESPONSE_TO_TSA_DN","description":"Cancer related genes down-regulated in any of four hepatoma cell lines following 24 h treatment with TSA [PubChem=5562]."} {"geneset":"KUNINGER_IGF1_VS_PDGFB_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUNINGER_IGF1_VS_PDGFB_TARGETS_UP","description":"Genes up-regulated in C2AS12 cells (myoblast) by IGF1 [GeneID=3479] vs PDGFB [GeneID=5155]."} {"geneset":"BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN","description":"Genes down-regulated in patients at the incipient stage of Alzheimer's disease."} {"geneset":"LIANG_SILENCED_BY_METHYLATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIANG_SILENCED_BY_METHYLATION_UP","description":"Genes up-regulated in LD419 cells (fibroblast) after treatment with decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]."} {"geneset":"SONG_TARGETS_OF_IE86_CMV_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SONG_TARGETS_OF_IE86_CMV_PROTEIN","description":"Cellular genes up-regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector."} {"geneset":"LEE_CALORIE_RESTRICTION_NEOCORTEX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_CALORIE_RESTRICTION_NEOCORTEX_DN","description":"Down-regulated in the neocortex of aged (30-month) mice subjected to caloric restriction since young adulthood."} {"geneset":"CUI_TCF21_TARGETS_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CUI_TCF21_TARGETS_2_UP","description":"All significantly up-regulated genes in kidney glomeruli isolated from TCF21 [Gene ID=6943] knockout mice."} {"geneset":"SESTO_RESPONSE_TO_UV_C1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C1","description":"Cluster 1: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"LY_AGING_MIDDLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LY_AGING_MIDDLE_UP","description":"Genes up-regulated in fibroblasts from middle-age individuals, compared to those from the young donors."} {"geneset":"WENG_POR_TARGETS_GLOBAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WENG_POR_TARGETS_GLOBAL_UP","description":"Genes up-regulated in liver from transgenic mice with reduced expression of POR [GeneID=5447] in all tissues."} {"geneset":"WU_HBX_TARGETS_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_HBX_TARGETS_1_UP","description":"Genes up-regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] in SK-Hep-1 cells (hepatocellular carcinoma)."} {"geneset":"GEISS_RESPONSE_TO_DSRNA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GEISS_RESPONSE_TO_DSRNA_UP","description":"Genes up-pregulated by dsRNA in GRE cells (glioma; no interferon system)."} {"geneset":"ABE_VEGFA_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABE_VEGFA_TARGETS","description":"Genes most profoundly induced in HUVEC cells (endothelium) by VEGFA [GeneID=7422]."} {"geneset":"MMS_MOUSE_LYMPH_HIGH_4HRS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MMS_MOUSE_LYMPH_HIGH_4HRS_UP","description":"Up-regulated at 4 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a high dose of methyl methanesulfonate (MMS)"} {"geneset":"BURTON_ADIPOGENESIS_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_1","description":"Strongly up-regulated at 2 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"LIANG_SILENCED_BY_METHYLATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIANG_SILENCED_BY_METHYLATION_DN","description":"Genes down-regulated in LD419 cells (fibroblast) after treatment with decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]."} {"geneset":"MOREIRA_RESPONSE_TO_TSA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOREIRA_RESPONSE_TO_TSA_DN","description":"Down-regulated in CD4+ [GeneID=920] T lymphocytes after 4 h treatment with 100 nM TSA [PubChem=5562]."} {"geneset":"WENG_POR_TARGETS_GLOBAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WENG_POR_TARGETS_GLOBAL_DN","description":"Genes down-regulated in liver from transgenic mice with reduced expression of POR [GeneID=5447] in all tissues."} {"geneset":"BURTON_ADIPOGENESIS_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_7","description":"Down-regulated at 48-96 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"KEEN_RESPONSE_TO_ROSIGLITAZONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KEEN_RESPONSE_TO_ROSIGLITAZONE_DN","description":"Genes down-regulated in aorta biopsies from mice treated with rosiglitazone [PubChem=77999]."} {"geneset":"BROWNE_HCMV_INFECTION_10HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_10HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 10 h time point that were not up-regulated at the previous time point, 8 h."} {"geneset":"LIU_SMARCA4_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_SMARCA4_TARGETS","description":"Genes up-regulated in SW-13 cells (kidney cancer) by transient expression of SMARCA4 [GeneID=6597] at 24 h off a plasmid vector."} {"geneset":"HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2","description":"Genes differentially expressed in hereditary breast cancer tumors with mutated BRCA1 [GeneID=672] compared to those with mutated BRCA2 [GeneID=675]."} {"geneset":"GENTILE_UV_RESPONSE_CLUSTER_D1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_RESPONSE_CLUSTER_D1","description":"Cluster d1: genes down-regulated in WS1 cells (fibroblast) at 6 h after irradiation with high dose UV-C."} {"geneset":"DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN","description":"Genes down-regulated in HEK293 cells (embryonic kidney) at 6 h, 12 h or 24 h after infection with reovirus strain T3A (known as a strong inducer of apoptosis)."} {"geneset":"RAMPON_ENRICHED_LEARNING_ENVIRONMENT_EARLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMPON_ENRICHED_LEARNING_ENVIRONMENT_EARLY_UP","description":"Genes up-regulated in the brain cortex of mice that were exposed to an enriched learning environment for one day."} {"geneset":"SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN","description":"Genes down-regulated in 3T3-L1 cells (adipocyte) by insulin [GeneID=3630] but displayed blunted response to insulin the insulin resistant cells."} {"geneset":"ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN","description":"Genes up-regulated in A549 cells (lung carcinoma) upon infection with RSV (respiratory syncytial virus) and down-regulated by further treatment with ribavirin [PubChem=5064]."} {"geneset":"SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_DN","description":"Down-regulated in murine dorsal skin cells at 6 h after treatment with the phorbol ester carcinogen TPA [PubChem=4792]."} {"geneset":"DELASERNA_TARGETS_OF_MYOD_AND_SMARCA4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELASERNA_TARGETS_OF_MYOD_AND_SMARCA4","description":"Genes up-regulated in NIH 3T3 cells (fibroblasts) 24 h after inducing MYOD [GeneID=4654] which were down-regulated by dominant negative form of SMARCA4 [GeneID=6597]."} {"geneset":"BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN","description":"Genes specifically down-regulated in FL5.12 cells (pro-B lymphocyte) by camptothecin [PubChem=2538]."} {"geneset":"WHITESIDE_CISPLATIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITESIDE_CISPLATIN_RESISTANCE_DN","description":"Genes down-regulated in NCI-H2170 cells (lung cancer) upon induction of resistance to cisplatin [PubChem=2767]."} {"geneset":"BURTON_ADIPOGENESIS_PEAK_AT_0HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_PEAK_AT_0HR","description":"Cluster 1: genes progressively down-regulated over 24 h (peak at 0 h timepoint) during differentiation of 3T3-L1 fibroblasts into adipocytes in response to adipogenic hormones."} {"geneset":"JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP","description":"Up-regulated genes distinguishing between breast cancer tumors with mutated BRCA1 [GeneID=672] from those with mutated BRCA2 [GeneID=675]."} {"geneset":"JACKSON_DNMT1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JACKSON_DNMT1_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) upon Cre-lox knockout of DNMT1 [GeneID=1786]."} {"geneset":"DAZARD_RESPONSE_TO_UV_NHEK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_RESPONSE_TO_UV_NHEK_DN","description":"Genes down-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation."} {"geneset":"BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_UP","description":"Genes up-regulated in A172 cells (glioma, does not express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 48 h."} {"geneset":"KYNG_RESPONSE_TO_H2O2_VIA_ERCC6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_RESPONSE_TO_H2O2_VIA_ERCC6","description":"Genes down-regulated in CS-B cells (Cockayne syndrome fibroblast, CS) with defficient ERCC6 [GeneID=2074] in response to hydrogen peroxide [PubChem=784]."} {"geneset":"KALMA_E2F1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KALMA_E2F1_TARGETS","description":"DNA replication genes up-regulated in a Rat-1a cell line (fibroblast) by expression of E2F1 [GeneID=1869]."} {"geneset":"VERRECCHIA_RESPONSE_TO_TGFB1_C4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERRECCHIA_RESPONSE_TO_TGFB1_C4","description":"Cluster 4: ECM related genes up-regulated in dermal fibroblasts later than 30 min after TGFB1 [GeneID=7040] addition; kept increasing with time."} {"geneset":"ZHU_CMV_24_HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHU_CMV_24_HR_UP","description":"Up-regulated at 24 h following infection of primary human foreskin fibroblasts with CMV"} {"geneset":"NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_UP","description":"Top 20 genes whose up-regulation correlated with gastrointestinal stromal tumors (GIST) and synovial sarcoma compared to other tumors."} {"geneset":"BURTON_ADIPOGENESIS_11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_11","description":"Strongly down-regulated at 2-96 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"BROWNE_HCMV_INFECTION_12HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_12HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 12 h time point that were not up-regulated at the previous time point, 10 h."} {"geneset":"NIELSEN_SCHWANNOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_SCHWANNOMA_UP","description":"Top 20 positive significant genes associated with schwannoma tumors."} {"geneset":"IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR","description":"Genes in the expression cluster 'HSC and Progenitors Shared': up-regulated in hematopoietic stem cells (HSC) and progenitors from adult bone marrow and fetal liver."} {"geneset":"RAMASWAMY_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMASWAMY_METASTASIS_UP","description":"Up-regulated genes in metastatic vs primary solid tumors."} {"geneset":"DAZARD_RESPONSE_TO_UV_SCC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_RESPONSE_TO_UV_SCC_UP","description":"Genes up-regulated in SCC12B2 cells (squamous cell carcinoma) by UV-B irradiation."} {"geneset":"KAYO_CALORIE_RESTRICTION_MUSCLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAYO_CALORIE_RESTRICTION_MUSCLE_UP","description":"Upregulated in the vastus lateralis muscle of middle aged rhesus monkeys subjected to caloric restriction since young adulthood vs age matched controls"} {"geneset":"JIANG_HYPOXIA_NORMAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_HYPOXIA_NORMAL","description":"Genes up-regulated in RPTEC cells (normal kidney) by hypoxia."} {"geneset":"BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_DN","description":"Genes down-regulated in A172 cells (glioma, does not express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 48 h."} {"geneset":"ABE_INNER_EAR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABE_INNER_EAR","description":"Genes prefentially expressed in human inner ear tissue (cochlea and vestibule), at least 10-fold higher from a mixture of 29 other tissues."} {"geneset":"MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_5","description":"Cluster 5: genes up-regulated in SW260 cells (colon cancer) by curcumin and sulindac [PubChem=969516;5352]."} {"geneset":"TSENG_IRS1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSENG_IRS1_TARGETS_UP","description":"Up-regulated in brown preadipocytes with IRS1 [GeneID=3667] knockout vs wild type controls; the knockouts have severe defects in adipocyte differentiation."} {"geneset":"SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP","description":"Genes up-regulated in 3T3-L1 cells (adipocyte) by insulin [GeneID=3630] but displayed blunted response to insulin the insulin resistant cells."} {"geneset":"XU_GH1_AUTOCRINE_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_GH1_AUTOCRINE_TARGETS_UP","description":"Genes up-regulated in MFCF-7 cells (breast cancer) upon stable autocrine expression of HG1 [GeneID=2688]."} {"geneset":"XU_GH1_EXOGENOUS_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_GH1_EXOGENOUS_TARGETS_DN","description":"Genes down-regulated in MFCF-7 cells (breast cancer) by exogenous HG1 [GeneID=2688]."} {"geneset":"BAELDE_DIABETIC_NEPHROPATHY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAELDE_DIABETIC_NEPHROPATHY_DN","description":"Genes down-regulated in glomeruli of kidneys from patients with diabetic nephropathy (type 2 diabetes mellitus)."} {"geneset":"BROWNE_HCMV_INFECTION_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_6HR_UP","description":"Genes up-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 6 h time point that were not up-regulated at the previous time point, 4 h."} {"geneset":"DAZARD_UV_RESPONSE_CLUSTER_G1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G1","description":"Cluster G1: genes most highly up-regulated in NHEK cells (normal keratinocyte) between 6 h and 12 h after UV-B irradiation."} {"geneset":"LY_AGING_OLD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LY_AGING_OLD_DN","description":"Genes down-regulated in fibroblasts from old individuals, compared to those from young donors."} {"geneset":"WENG_POR_DOSAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WENG_POR_DOSAGE","description":"Genes up-regulated in liver from mice with liver specific knockout of POR [GeneID=5447] vs mice with reduced expression of POR in all tissues."} {"geneset":"MURAKAMI_UV_RESPONSE_24HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MURAKAMI_UV_RESPONSE_24HR","description":"Genes down-regulated in primary keratinocytes at 24 h after UVB irradiation."} {"geneset":"SEMENZA_HIF1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEMENZA_HIF1_TARGETS","description":"Genes that are transcriptionally regulated by HIF1A [GeneID=3091]."} {"geneset":"BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_DN","description":"Genes down-regulated in D-341 MED (OBR) cells (medulloblastoma) resistant to both carmustine and O6-BG [PubChem=2578;4578]."} {"geneset":"WANG_CISPLATIN_RESPONSE_AND_XPC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_CISPLATIN_RESPONSE_AND_XPC_UP","description":"Genes up-regulated in fibroblasts with defective XPC [GeneID=7508] in response to cisplatin [PubChem=2767]."} {"geneset":"VARELA_ZMPSTE24_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VARELA_ZMPSTE24_TARGETS_UP","description":"Top genes up-regulated in liver tissue from mice with knockout of ZMPSTE24 [GeneID=10269]."} {"geneset":"YIH_RESPONSE_TO_ARSENITE_C3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YIH_RESPONSE_TO_ARSENITE_C3","description":"Genes in cluster 3: delayed up-regulation in HFW cells (fibroblast) by sodium arsenite [PubChem=26435]."} {"geneset":"SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER","description":"50 most interesting genes up-regulated in pancreatic cancer cell lines (AsPC1, Hs766T, MiaPaCa2, Panc1) but not in the non-neoplastic cells (HPDE) by TSA [PubChem=5562]."} {"geneset":"CHENG_RESPONSE_TO_NICKEL_ACETATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHENG_RESPONSE_TO_NICKEL_ACETATE","description":"Genes down-regulated in HPL1D cells (lung epithelium) upon exposure to nickel acetate [PubChem=9756]."} {"geneset":"TSENG_ADIPOGENIC_POTENTIAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSENG_ADIPOGENIC_POTENTIAL_DN","description":"Genes showing decreasing expression in brown preadipocytes with increasing ability of the cells to differentiate."} {"geneset":"DAZARD_UV_RESPONSE_CLUSTER_G6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G6","description":"Cluster G6: genes increasingly down-regulated in NHEK cells (normal keratinocyte) after UV-B irradiation."} {"geneset":"NIELSEN_LEIOMYOSARCOMA_CNN1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_LEIOMYOSARCOMA_CNN1_UP","description":"Top 20 positive significant genes associated with leiomyosarcoma tumors expressing muscle gene cluster with CNN1 [GeneID=1264]."} {"geneset":"XU_GH1_AUTOCRINE_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XU_GH1_AUTOCRINE_TARGETS_DN","description":"Genes down-regulated in MFCF-7 cells (breast cancer) upon stable autocrine expression of HG1 [GeneID=2688]."} {"geneset":"SESTO_RESPONSE_TO_UV_C7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C7","description":"Cluster 7: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"KAAB_FAILED_HEART_VENTRICLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAAB_FAILED_HEART_VENTRICLE_DN","description":"Genes down-regulated in the ventricles of failing hearts (DCM and ICM) compared to the healthy controls."} {"geneset":"JIANG_HYPOXIA_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_HYPOXIA_CANCER","description":"Genes up-regulated in 786-0 cells (renal carcinoma, RCC) by hypoxia and in the absensce of VHL [GeneID=7428]."} {"geneset":"ZAMORA_NOS2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZAMORA_NOS2_TARGETS_DN","description":"Down-regulated in hepatocytes upon expression of NOS2 [GeneID=4843]."} {"geneset":"YIH_RESPONSE_TO_ARSENITE_C1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YIH_RESPONSE_TO_ARSENITE_C1","description":"Genes in cluster 1: strongly up-regulated in HFW cells (fibroblast) upon treatment with sodium arsenite [PubChem=26435] at all time points."} {"geneset":"BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN","description":"Genes down-regulated in T98G cells (glioma, express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 48 h."} {"geneset":"BURTON_ADIPOGENESIS_PEAK_AT_8HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_PEAK_AT_8HR","description":"Cluster 3: genes maximally expressed at 8 hr time point during differentiation of 3T3-L1 fibroblasts into adipocytes in response to adipogenic hormones."} {"geneset":"SIMBULAN_PARP1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIMBULAN_PARP1_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblasts) from PARP1 [GeneID=142] knockout mice."} {"geneset":"SAFFORD_T_LYMPHOCYTE_ANERGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAFFORD_T_LYMPHOCYTE_ANERGY","description":"Genes up-regulated in anergic mouse T helper cells (A.E7), versus non-anergic stimulated controls"} {"geneset":"WU_HBX_TARGETS_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_HBX_TARGETS_2_UP","description":"Genes up-regulated by expression of HBV X protein (HBVgp3) [GeneID=944566] in primary hepatocytes."} {"geneset":"SESTO_RESPONSE_TO_UV_C5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C5","description":"Cluster 5: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"LI_ADIPOGENESIS_BY_ACTIVATED_PPARG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_ADIPOGENESIS_BY_ACTIVATED_PPARG","description":"Adipocyte genes induced in 3T3-L1 cells (adipocyte) by constitutively active PPARG [GeneID=5468] or its agonist, TZD [PubChem=5437]."} {"geneset":"NIELSEN_LEIOMYOSARCOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_LEIOMYOSARCOMA_UP","description":"Top 20 positive significant genes associated with CNN1 [GeneID=1264] negative leiomyosarcoma tumors."} {"geneset":"LY_AGING_MIDDLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LY_AGING_MIDDLE_DN","description":"Genes down-regulated in fibroblasts from middle-age individuals, compared to those from the young donors."} {"geneset":"BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_UP","description":"Genes up-regulated in D-341 MED (OBR) cells (medulloblastoma) resistant to both carmustine and O6-BG [PubChem=2578;4578]."} {"geneset":"SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1","description":"Genes up-regulated in the pancreatic cancer cell lines (AsPC1, Hs766T, MiaPaCa2, Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]."} {"geneset":"WENG_POR_TARGETS_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WENG_POR_TARGETS_LIVER_UP","description":"Genes up-regulated in liver from mice with liver specific knockout of POR [GeneID=5447]."} {"geneset":"HU_GENOTOXIC_DAMAGE_4HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HU_GENOTOXIC_DAMAGE_4HR","description":"Genes most consistently regulated at 4 h by all six genotoxins tested: cisplatin, methyl methanesulfonate, mitomycin C, taxol, hydroxyurea and etoposide [PubChem=2767;4156;5746;4666;3657;36462]."} {"geneset":"MCDOWELL_ACUTE_LUNG_INJURY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCDOWELL_ACUTE_LUNG_INJURY_DN","description":"Genes down-regulated in the mouse model of acute lung injury induced by inhaling nickel sulfate [PubChem=24586]."} {"geneset":"RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP","description":"Genes up-regulated in the brain cortex of mice that were exposed to an enriched learning environment for 2 or 14 days."} {"geneset":"MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_6","description":"Cluster 6: genes down-regulated in SW260 cells (colon cancer) by sodium butyrate and sulindac [PubChem=5222465;5352]."} {"geneset":"GENTILE_UV_LOW_DOSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_LOW_DOSE_DN","description":"Selected genes down-regulated in WS1 (fibroblast) in response to irradiation with low dose UV-C."} {"geneset":"SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_DN","description":"Genes down-regulated in 3T3-L1 cells (adipocyte) by insulin [GeneID=3630] which continued to respond normally to insulin in the insulin resistant cells."} {"geneset":"BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_UP","description":"Genes up-regulated in T98G cells (glioma, express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 48 h."} {"geneset":"GENTILE_UV_RESPONSE_CLUSTER_D8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_UV_RESPONSE_CLUSTER_D8","description":"Cluster d8: genes progressively down-regulated in WS1 cells (fibroblast) through 18 h after irradiation with high dose UV-C."} {"geneset":"BROWNE_HCMV_INFECTION_24HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_24HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 24 h time point that were not up-regulated at the previous time point, 20 h."} {"geneset":"WANG_SMARCE1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_SMARCE1_TARGETS_UP","description":"Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector."} {"geneset":"SESTO_RESPONSE_TO_UV_C3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SESTO_RESPONSE_TO_UV_C3","description":"Cluster 3: genes changed in primary keratinocytes by UVB irradiation."} {"geneset":"HAN_JNK_SINGALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAN_JNK_SINGALING_DN","description":"Genes down-regulated in 3T3 cells (fibroblast) upon activation of JNK pathway."} {"geneset":"KRASNOSELSKAYA_ILF3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRASNOSELSKAYA_ILF3_TARGETS_DN","description":"Down-regulated in GHOST(3)CXCR4 cells (osteosarcoma) upon ectopic expression of ILF3 [GeneID=3609]."} {"geneset":"GENTILE_RESPONSE_CLUSTER_D3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTILE_RESPONSE_CLUSTER_D3","description":"Cluster d3: genes progressively down-regulated in WS1 cells (fibroblast) through 12 h irradiation with high dose UV-C."} {"geneset":"JI_RESPONSE_TO_FSH_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JI_RESPONSE_TO_FSH_UP","description":"Genes up-regulated in MCV152 cells (ovarian cancer) treated with follicle stimulating hormone (FSH)."} {"geneset":"LEE_CALORIE_RESTRICTION_MUSCLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_CALORIE_RESTRICTION_MUSCLE_DN","description":"Down-regulated in the gastrocnemius muscle of aged (30-month) mice subjected to caloric restriction diet since young adulthood."} {"geneset":"ABE_VEGFA_TARGETS_30MIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABE_VEGFA_TARGETS_30MIN","description":"Genes up-regulated in HUVEC cells (endothelium) at 30 min after VEGFA [GeneID=7422] stimulation."} {"geneset":"BROWNE_HCMV_INFECTION_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_6HR_DN","description":"Genes down-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 6 h time point that were not down-regulated at the previous time point, 4 h."} {"geneset":"LEE_AGING_MUSCLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_AGING_MUSCLE_UP","description":"Upregulated in the gastrocnemius muscle of aged adult mice (30-month) vs young adult (5-month)"} {"geneset":"CARDOSO_RESPONSE_TO_GAMMA_RADIATION_AND_3AB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CARDOSO_RESPONSE_TO_GAMMA_RADIATION_AND_3AB","description":"Down-regulated synergystically by gamma-irradiation and 3-aminobenzamine [PubChem=1645], an inhibitor of PARP1 [GeneID=142]."} {"geneset":"MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_DN","description":"Genes similarly down-regulated in 3T3-L1 cells (fibroblasts able to differentiate to adipocytes) upon stimulation of INSR or IGFR1 by NTF3 [GeneID=3643;3480;4908]."} {"geneset":"SASSON_FSH_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASSON_FSH_RESPONSE","description":"Genes up-regulated in rFSH-17 cells (primary granulosa) after stimulation with FSH."} {"geneset":"CHEN_ETV5_TARGETS_TESTIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_ETV5_TARGETS_TESTIS","description":"Genes down-regulated in testis from 4 week old ETV5 [GeneID=2119] knockout mice."} {"geneset":"ZHU_CMV_8_HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHU_CMV_8_HR_UP","description":"Up-regulated at 8 h following infection of primary human foreskin fibroblasts with CMV"} {"geneset":"WELCSH_BRCA1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WELCSH_BRCA1_TARGETS_DN","description":"Down-regulated by induction of exogenous BRCA1 in EcR-293 cells"} {"geneset":"DASU_IL6_SIGNALING_SCAR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DASU_IL6_SIGNALING_SCAR_DN","description":"Genes down-regulated in hypertrophic scar fibroblasts in response to IL6 [GeneID=3569]."} {"geneset":"JIANG_AGING_CEREBRAL_CORTEX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_AGING_CEREBRAL_CORTEX_DN","description":"Down-regulated in the cerebral cortex of aged (22 months) BALB/c mice, compared to young (2 months) controls"} {"geneset":"MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN","description":"Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]."} {"geneset":"BURTON_ADIPOGENESIS_9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_9","description":"Strongly down-regulated at 8-96 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"URS_ADIPOCYTE_DIFFERENTIATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/URS_ADIPOCYTE_DIFFERENTIATION_DN","description":"Genes down-regulated in primary adipocytes compared to preadipocytes."} {"geneset":"TRACEY_RESISTANCE_TO_IFNA2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TRACEY_RESISTANCE_TO_IFNA2_DN","description":"Genes down-regulated in huT78R cells (cutaneous T-cell lymphoma, CTCL) resistant to IFNA2 [GeneID=3440] compared to the IFN2A sensitive parental cell line."} {"geneset":"VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_DN","description":"Genes down-regulated after heat shock in peripheral lympocytes from old donors, compared to those from the young ones."} {"geneset":"BROWNE_HCMV_INFECTION_12HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_12HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 12 h time point that were not down-regulated at the previous time point, 10 h."} {"geneset":"MAHAJAN_RESPONSE_TO_IL1A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAHAJAN_RESPONSE_TO_IL1A_UP","description":"Genes up-regulated in corneal fibroblasts after treatment with IL1A [GeneID=3552]."} {"geneset":"JIANG_AGING_HYPOTHALAMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_AGING_HYPOTHALAMUS_UP","description":"Up-regulated in the hypothalamus of aged (22 months) BALB/c mice, compared to young (2 months) controls"} {"geneset":"KYNG_RESPONSE_TO_H2O2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_RESPONSE_TO_H2O2","description":"Genes up-regulated in response to hydrogen peroxide [PubChem=784] in CS-B cells (Cockayne syndrome fibroblast, CS) expressing ERCC6 [GeneID=2074] off a plasmid vector."} {"geneset":"DAZARD_UV_RESPONSE_CLUSTER_G2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G2","description":"Cluster G2: genes increasingly up-regulated in NHEK cells (normal keratinocyte) and reaching maximum levels at 12 h and 24 h after UV-B irradiation."} {"geneset":"VERRECCHIA_RESPONSE_TO_TGFB1_C3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERRECCHIA_RESPONSE_TO_TGFB1_C3","description":"Cluster 3: ECM related genes up-regulated in dermal fibroblasts within 30 min after TGFB1 [GeneID=7040] addition; returned rapidly to basal level after that."} {"geneset":"WESTON_VEGFA_TARGETS_3HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WESTON_VEGFA_TARGETS_3HR","description":"Genes up-regulated in MMEC cells (myometrial endothelium) at 3 h after VEGFA [GeneID=7422] stimulation."} {"geneset":"TSENG_ADIPOGENIC_POTENTIAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSENG_ADIPOGENIC_POTENTIAL_UP","description":"Genes showing increasing expression in brown preadipocytes with decreasing ability of the cells to differentiate."} {"geneset":"JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP","description":"Genes up-regulated in H460 cells (non-small cell lung carcinoma, NSCLC) after treatment with sodium butyrate [PubChem=5222465]."} {"geneset":"MCLACHLAN_DENTAL_CARIES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCLACHLAN_DENTAL_CARIES_UP","description":"Genes up-regulated in pulpal tissue extracted from carious teeth."} {"geneset":"GERHOLD_ADIPOGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GERHOLD_ADIPOGENESIS_UP","description":"Selected genes up-regulated during differentiation of 3T3-L1 cells (fibroblast) into adipocytes in response to adipogenic hormones."} {"geneset":"WENG_POR_TARGETS_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WENG_POR_TARGETS_LIVER_DN","description":"Genes down-regulated in liver from mice with liver specific knockout of POR [GeneID=5447]."} {"geneset":"SU_PLACENTA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SU_PLACENTA","description":"Genes up-regulated specifically in human placenta."} {"geneset":"BURTON_ADIPOGENESIS_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_6","description":"Strongly up-regulated at 96 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes."} {"geneset":"SUZUKI_RESPONSE_TO_TSA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUZUKI_RESPONSE_TO_TSA","description":"Genes up-regulated by TSA alone [PubChem=5562], with non-hypermethylated promoters, in RKO cells (colorectal cancer)."} {"geneset":"BURTON_ADIPOGENESIS_PEAK_AT_16HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BURTON_ADIPOGENESIS_PEAK_AT_16HR","description":"Cluster 4: genes maximally expressed at 16 h time point during differentiation of 3T3-L1 fibroblasts into adipocytes in response to adipogenic hormones."} {"geneset":"MARCHINI_TRABECTEDIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARCHINI_TRABECTEDIN_RESISTANCE_DN","description":"Genes down-regulated in chondrosarcoma and ovarian carcinoma cell lines which developed resistance to trabectedin [PubChem=3199]."} {"geneset":"BILD_MYC_ONCOGENIC_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILD_MYC_ONCOGENIC_SIGNATURE","description":"Genes selected in supervised analyses to discriminate cells expressing c-Myc [GeneID=4609] from control cells expressing GFP."} {"geneset":"BILD_E2F3_ONCOGENIC_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILD_E2F3_ONCOGENIC_SIGNATURE","description":"Genes selected in supervised analyses to discriminate cells expressing E2F3 [GeneID=1871] from control cells expressing GFP."} {"geneset":"BILD_HRAS_ONCOGENIC_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILD_HRAS_ONCOGENIC_SIGNATURE","description":"Genes selected in supervised analyses to discriminate cells expressing activated HRAS [GeneID=3265] oncogene from control cells expressing GFP."} {"geneset":"BILD_SRC_ONCOGENIC_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILD_SRC_ONCOGENIC_SIGNATURE","description":"Genes selected in supervised analyses to discriminate cells expressing c-Src (CSK) [GeneID=1445] from control cells expressing GFP."} {"geneset":"BILD_CTNNB1_ONCOGENIC_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILD_CTNNB1_ONCOGENIC_SIGNATURE","description":"Genes selected in supervised analyses to discriminate cells expressing activated beta-catenin (CTNNB1) [GeneID=1499] oncogene from control cells expressing GFP."} {"geneset":"DOUGLAS_BMI1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DOUGLAS_BMI1_TARGETS_UP","description":"Genes up-regulated in A4573 cells (Ewing's sarcoma, ESFT) after knockdown of BMI1 [GeneID=648] by RNAi."} {"geneset":"DOUGLAS_BMI1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DOUGLAS_BMI1_TARGETS_DN","description":"Genes down-regulated in A4573 cells (Ewing's sarcoma, ESFT) after knockdown of BMI1 [GeneID=648] by RNAi."} {"geneset":"KRIGE_AMINO_ACID_DEPRIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRIGE_AMINO_ACID_DEPRIVATION","description":"The 'amino acid deprivation response' (AADR): genes up-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after amino acid deprivation or treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703]."} {"geneset":"KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP","description":"Genes up-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h."} {"geneset":"KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN","description":"Genes down-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h."} {"geneset":"KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP","description":"Genes up-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h."} {"geneset":"KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN","description":"Genes down-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h."} {"geneset":"GHO_ATF5_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GHO_ATF5_TARGETS_UP","description":"Genes up-regulated in HEP3B cells (liver cancer) overexpressing ATF5 [GeneID=22809] off a plasmid vector."} {"geneset":"GHO_ATF5_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GHO_ATF5_TARGETS_DN","description":"Genes down-regulated in HEP3B cells (liver cancer) overexpressing ATF5 [GeneID=22809] off a plasmid vector."} {"geneset":"DURCHDEWALD_SKIN_CARCINOGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DURCHDEWALD_SKIN_CARCINOGENESIS_UP","description":"Genes up-regulated upon skin specific knockout of FOS [GeneID=2353] by cre-lox in the K5-SOS-F mice (express a constitutively active form of SOS1 [GeneID=6654] in the skin)."} {"geneset":"DURCHDEWALD_SKIN_CARCINOGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DURCHDEWALD_SKIN_CARCINOGENESIS_DN","description":"Genes down-regulated upon skin specific knockout of FOS [GeneID=2353] by cre-lox in the K5-SOS-F mice (express a constitutively active form of SOS1 [GeneID=6654] in the skin)."} {"geneset":"LI_CYTIDINE_ANALOGS_CYCTOTOXICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_CYTIDINE_ANALOGS_CYCTOTOXICITY","description":"Genes whose expression in a panel of lymphoblastoid cell lines was associated with cytotoxicity of the anti-cancer analogs of cytidine, gemcitabine and cytarabine [PubChem=596;3461;6253]."} {"geneset":"LI_CYTIDINE_ANALOG_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_CYTIDINE_ANALOG_PATHWAY","description":"The 'cytidine analog pathway': genes involved in transport and metabolism of the anti-cancer analogs of cytidine: gemcitabine and cytarabine [PubChem=596;3461;6253]."} {"geneset":"KIM_LRRC3B_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_LRRC3B_TARGETS","description":"Immune response genes up-regulated in zenograft tumors formed by SNU-601 cells (gastric cancer) made to express LRRC3B [GeneID=116135]."} {"geneset":"ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE","description":"Proteins secreted in co-culture of LKR-13 tumor cells (non-small cell lung cancer, NSCLC) and MHS stroma cells (macrophages)."} {"geneset":"ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM","description":"Proteins secreted in co-culture of LKR-13 tumor cells (non-small cell lung cancer, NSCLC) and MEC stroma cells (endothelium)."} {"geneset":"ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST","description":"Proteins secreted in co-culture of LKR-13 tumor cells (non-small cell lung cancer, NSCLC) and MLg stroma cells (fibroblasts)."} {"geneset":"CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP","description":"Selected genes up-regulated during invasion of lymphatic vessels during metastasis."} {"geneset":"CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN","description":"Selected genes down-regulated during invasion of lymphatic vessels during metastasis."} {"geneset":"YANG_MUC2_TARGETS_DUODENUM_3MO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_MUC2_TARGETS_DUODENUM_3MO_DN","description":"Genes down-regulated in duodenum of 3 month old MUC2 [GeneID=4583] knockout mice."} {"geneset":"YANG_MUC2_TARGETS_DUODENUM_6MO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_MUC2_TARGETS_DUODENUM_6MO_UP","description":"Genes up-regulated in duodenum of 6 month old MUC2 [GeneID=4583] knockout mice."} {"geneset":"YANG_MUC2_TARGETS_DUODENUM_6MO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_MUC2_TARGETS_DUODENUM_6MO_DN","description":"Genes down-regulated in duodenum of 6 month old MUC2 [GeneID=4583] knockout mice."} {"geneset":"YANG_MUC2_TARGETS_COLON_3MO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_MUC2_TARGETS_COLON_3MO_DN","description":"Genes down-regulated in colon of 3 month old MUC2 [GeneID=4583] knockout mice."} {"geneset":"MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP","description":"The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma."} {"geneset":"MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN","description":"The postradiation tumor escape signature: genes down-regulated in tumors from irradiated stroma vs those from non-irradiated stroma."} {"geneset":"MCCOLLUM_GELDANAMYCIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCOLLUM_GELDANAMYCIN_RESISTANCE_UP","description":"Genes up-regulated in A549GARS cells (lung cancer) resistant to the geldanamycin and 17-AAG [PubChem=5476289;6440175]."} {"geneset":"MCCOLLUM_GELDANAMYCIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCOLLUM_GELDANAMYCIN_RESISTANCE_DN","description":"Genes down-regulated in A549GARS cells (lung cancer) resistant to the geldanamycin and 17-AAG [PubChem=5476289;6440175]."} {"geneset":"CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1","description":"The 'group 1 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [GeneID=2099;2064]."} {"geneset":"CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2","description":"The 'group 2 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [GeneID=2099;2064]."} {"geneset":"CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3","description":"The 'group 3 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [GeneID=2099;2064]."} {"geneset":"CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4","description":"The 'group 4 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 but not ERBB2 [GeneID=2099;2064]."} {"geneset":"CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5","description":"The 'group 5 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 but not ERBB2 [GeneID=2099;2064]."} {"geneset":"MILICIC_FAMILIAL_ADENOMATOUS_POLYPOSIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MILICIC_FAMILIAL_ADENOMATOUS_POLYPOSIS_UP","description":"Top genes up-regulated in colon epithelium biopsies from FAP (familial adenomatous polyposis) patients with mutated APC [GeneID=324]."} {"geneset":"MILICIC_FAMILIAL_ADENOMATOUS_POLYPOSIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MILICIC_FAMILIAL_ADENOMATOUS_POLYPOSIS_DN","description":"Top genes down-regulated in colon epithelium biopsies from FAP (familial adenomatous polyposis) patients with mutated APC [GeneID=324]."} {"geneset":"SINGH_NFE2L2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SINGH_NFE2L2_TARGETS","description":"Selected electrophile and drug detoxication genes down-regulated in A549 and H460 cells (lung cancer) upon knockdown of NFE2L2 [GeneID=4780] by RNAi."} {"geneset":"PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP","description":"Antigen processing and presentation genes up-regulated in JY cells (B lymphocytes) treated with TSA [PubChem=5562]."} {"geneset":"PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN","description":"Antigen processing and presentation genes down-regulated in JY cells (B lymphocytes) treated with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"LOPES_METHYLATED_IN_COLON_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPES_METHYLATED_IN_COLON_CANCER_UP","description":"Genes methylated aberrantly in HCT116 and Colo320 (colon cancer) cells."} {"geneset":"LOPES_METHYLATED_IN_COLON_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPES_METHYLATED_IN_COLON_CANCER_DN","description":"Genes un-methylated aberrantly in HCT116 and Colo320 (colon cancer) cells."} {"geneset":"HARRIS_BRAIN_CANCER_PROGENITORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HARRIS_BRAIN_CANCER_PROGENITORS","description":"Genes from the brain cancer stem (cancer stem cell, CSC) signature."} {"geneset":"TUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_UP","description":"Genes up-regulated in small intestine tissue from transgenic mice expressing a mutant form of COL13A1 [GeneID=1305], compared to normal controls."} {"geneset":"TUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_DN","description":"Genes down-regulated in small intestine tissue from transgenic mice expressing a mutant form of COL13A1 [GeneID=1305], compared to normal controls."} {"geneset":"BAFNA_MUC4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAFNA_MUC4_TARGETS_UP","description":"Genes up-regulated in NIH3T3 cells (fibroblast) engineered to stably express MUC4 [GeneID=4585]."} {"geneset":"BAFNA_MUC4_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAFNA_MUC4_TARGETS_DN","description":"Genes down-regulated in NIH3T3 cells (fibroblast) engineered to stably express MUC4 [GeneID=4585]."} {"geneset":"HOWLIN_CITED1_TARGETS_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOWLIN_CITED1_TARGETS_1_UP","description":"Genes up-regulated in mammary glands from the CITED1 [GeneID=4435] knockout mice: homozygotic vs. heterozygotic animals."} {"geneset":"HOWLIN_CITED1_TARGETS_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOWLIN_CITED1_TARGETS_1_DN","description":"Genes down-regulated in mammary glands from the CITED1 [GeneID=4435] knockout mice: homozygotic vs. heterozygotic animals."} {"geneset":"HOWLIN_CITED1_TARGETS_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOWLIN_CITED1_TARGETS_2_UP","description":"Genes up-regulated in mammary glands from the CITED1 [GeneID=4435] knockout mice: homozygotic vs wild type (WT) animals."} {"geneset":"HOWLIN_CITED1_TARGETS_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOWLIN_CITED1_TARGETS_2_DN","description":"Genes down-regulated in mammary glands from the CITED1 [GeneID=4435] knockout mice: homozygotic vs wild type (WT) animals."} {"geneset":"HILLION_HMGA1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HILLION_HMGA1_TARGETS","description":"Genes changed in Rat1a cells (fibroblasts) by overexpression of HMGA1 isoform a [GeneID=3159] off a plasmid vector."} {"geneset":"HILLION_HMGA1B_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HILLION_HMGA1B_TARGETS","description":"Genes changed in Rat1a cells (fibroblasts) by overexpression of HMGA1 isoform b [GeneID=3159] off a plasmid vector."} {"geneset":"DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP","description":"Common up-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [GeneID=2071], after UVC irradiation."} {"geneset":"LEIN_NEURON_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_NEURON_MARKERS","description":"Genes enriched in neurons in the adult mouse brain identified through correlation-based searches seeded with neuron cell-type specific gene expression patterns."} {"geneset":"LEIN_ASTROCYTE_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_ASTROCYTE_MARKERS","description":"Genes enriched in astrocytes in the adult mouse brain identified through correlation-based searches seeded with the astrocyte cell-type specific gene expression patterns."} {"geneset":"LEIN_OLIGODENDROCYTE_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_OLIGODENDROCYTE_MARKERS","description":"Genes enriched in oligodendrocytes in the adult mouse brain identified through correlation-based searches seeded with the oligodendrocyte cell-type specific gene expression patterns."} {"geneset":"LEIN_CHOROID_PLEXUS_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_CHOROID_PLEXUS_MARKERS","description":"Genes enriched in choroid plexus cells in the brain identified through correlation-based searches seeded with the choroid plexus cell-type specific gene expression patterns."} {"geneset":"LEIN_MIDBRAIN_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_MIDBRAIN_MARKERS","description":"Top 100 ranked genes most specific to midbrain region of adult mouse brain."} {"geneset":"LEIN_PONS_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_PONS_MARKERS","description":"Top 100 ranked genes most specific to pons region (P) of the adult mouse brain."} {"geneset":"LEIN_MEDULLA_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_MEDULLA_MARKERS","description":"Top 100 ranked genes most specific to medulla (myelencephalon) hindbrain region of adult mouse brain."} {"geneset":"LEIN_CEREBELLUM_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_CEREBELLUM_MARKERS","description":"Top 100 ranked genes most specific to the cerebellum region of adult mouse brain."} {"geneset":"LEIN_LOCALIZED_TO_DISTAL_AND_PROXIMAL_DENDRITES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_LOCALIZED_TO_DISTAL_AND_PROXIMAL_DENDRITES","description":"Transcripts showing subcellular localization to both distal and proximal dendrites in the adult mouse brain."} {"geneset":"LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES","description":"Transcripts showing subcellular localization only to proximal dendrites in the adult mouse brain."} {"geneset":"GAVIN_FOXP3_TARGETS_CLUSTER_T4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_FOXP3_TARGETS_CLUSTER_T4","description":"Cluster T4 of genes with similar expression profiles in thymic T lymphocytes after FOXP3 [GeneID=50943] loss of function (LOF)."} {"geneset":"GAVIN_FOXP3_TARGETS_CLUSTER_T7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_FOXP3_TARGETS_CLUSTER_T7","description":"Cluster T7 of genes with similar expression profiles in thymic T lymphocytes after FOXP3 [GeneID=50943] loss of function (LOF)."} {"geneset":"GAVIN_FOXP3_TARGETS_CLUSTER_P2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_FOXP3_TARGETS_CLUSTER_P2","description":"Cluster P2 of genes with similar expression profiles in peripheral T ymphocytes after FOXP3 [GeneID=50943] loss of function (LOF)."} {"geneset":"GAVIN_FOXP3_TARGETS_CLUSTER_P3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_FOXP3_TARGETS_CLUSTER_P3","description":"Cluster P3 of genes with similar expression profiles in peripheral T lymphocytes after FOXP3 [GeneID=50943] loss of function (LOF)."} {"geneset":"GAVIN_FOXP3_TARGETS_CLUSTER_P4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_FOXP3_TARGETS_CLUSTER_P4","description":"Cluster P4 of genes with similar expression profiles in peripheral T lymphocytes after FOXP3 [GeneID=50943] loss of function (LOF)."} {"geneset":"GAVIN_FOXP3_TARGETS_CLUSTER_P6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_FOXP3_TARGETS_CLUSTER_P6","description":"Cluster P6 of genes with similar expression profiles in peripheral T lymphocytes after FOXP3 [GeneID=50943] loss of function (LOF)."} {"geneset":"GAVIN_FOXP3_TARGETS_CLUSTER_P7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_FOXP3_TARGETS_CLUSTER_P7","description":"Cluster P7 of genes with similar expression profiles in peripheral T lymphocytes after FOXP3 [GeneID=50943] loss of function (LOF)."} {"geneset":"GAVIN_PDE3B_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_PDE3B_TARGETS","description":"Genes changed in peripheral regulatory T lymphocytes that depend on PDE3B [GeneID=5140]."} {"geneset":"GAVIN_IL2_RESPONSIVE_FOXP3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_IL2_RESPONSIVE_FOXP3_TARGETS_UP","description":"FOXP3 [GeneID=50943] target genes up-regulated in T lymphocytes after stimulation with IL2 [GeneID=3558]."} {"geneset":"GAVIN_IL2_RESPONSIVE_FOXP3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAVIN_IL2_RESPONSIVE_FOXP3_TARGETS_DN","description":"FOXP3 [GeneID=50943] target genes down-regulated in T lymphocytes after stimulation with IL2 [GeneID=3558]."} {"geneset":"ZHENG_BOUND_BY_FOXP3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_BOUND_BY_FOXP3","description":"Genes whose promoters are bound by FOXP3 [GeneID=50943] based an a ChIP-chip analysis."} {"geneset":"MARSON_BOUND_BY_FOXP3_STIMULATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSON_BOUND_BY_FOXP3_STIMULATED","description":"Genes with promoters bound by FOXP3 [GeneID=50943] in hybridoma cells stimulated by PMA [PubChem=4792] and ionomycin [PubChem=3733]."} {"geneset":"MARSON_BOUND_BY_FOXP3_UNSTIMULATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSON_BOUND_BY_FOXP3_UNSTIMULATED","description":"Genes with promoters bound by FOXP3 [GeneID=50943] in unstimulated hybridoma cells."} {"geneset":"MARSON_BOUND_BY_E2F4_UNSTIMULATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSON_BOUND_BY_E2F4_UNSTIMULATED","description":"Genes with promoters bound by E2F4 [GeneID=1874] in unstimulated hybridoma cells."} {"geneset":"MARSON_FOXP3_TARGETS_STIMULATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSON_FOXP3_TARGETS_STIMULATED_UP","description":"Genes with promoters bound by FOXP3 [GeneID=50943], dependent on it, and up-regulated in hybridoma cells stimulated by PMA [PubChem=4792] and ionomycin [PubChem=3733]."} {"geneset":"MARSON_FOXP3_TARGETS_STIMULATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSON_FOXP3_TARGETS_STIMULATED_DN","description":"Genes with promoters bound by FOXP3 [GeneID=50943], dependent on it, and down-regulated in hybridoma cells stimulated by PMA [PubChem=4792] and ionomycin [PubChem=3733]."} {"geneset":"MARSON_FOXP3_CORE_DIRECT_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSON_FOXP3_CORE_DIRECT_TARGETS","description":"Direct FOXP3 [GeneID=50943] targets that exhibit consistent transcriptional behavior in hybridoma and in ex vivo T lymphocytes."} {"geneset":"ZHENG_FOXP3_TARGETS_IN_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_FOXP3_TARGETS_IN_THYMUS_UP","description":"Genes with promoters bound by FOXP3 [GeneID=50943] and which are up-regulated only in developing (located in the thymus) regulatory CD4+ [GeneID=920] T lymphocytes."} {"geneset":"ZHENG_FOXP3_TARGETS_IN_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_FOXP3_TARGETS_IN_THYMUS_DN","description":"Genes with promoters bound by FOXP3 [GeneID=50943] and which are down-regulated only in developing (located in the thymus) regulatory CD4+ [GeneID=920] T lymphocytes."} {"geneset":"ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_UP","description":"Genes with promoters bound by FOXP3 [GeneID=50943] and which are up-regulated only in mature (peripheral blood) regulatory CD4+ [GeneID=920] T lymphocytes."} {"geneset":"ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN","description":"Genes with promoters bound by FOXP3 [GeneID=50943] and which are down-regulated only in mature (peripheral blood) regulatory CD4+ [GeneID=920] T lymphocytes."} {"geneset":"ZHENG_FOXP3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_FOXP3_TARGETS_UP","description":"Genes with promoters bound by FOXP3 [GeneID=50943] and which are up-regulated both in developing (located in the thymus) and mature (from peripheral blood) regulatory CD4+ [GeneID=920] T lymphocytes."} {"geneset":"ZHENG_FOXP3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_FOXP3_TARGETS_DN","description":"Genes with promoters bound by FOXP3 [GeneID=50943] and which are down-regulated both in developing (located in the thymus) and mature (from peripheral blood) regulatory CD4+ [GeneID=920] T lymphocytes."} {"geneset":"SANSOM_APC_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANSOM_APC_TARGETS","description":"Genes up-regulated after Cre-lox knockout of APC [GeneID=324] in the small intestine."} {"geneset":"SANSOM_APC_MYC_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANSOM_APC_MYC_TARGETS","description":"Genes down-regulated after double Cre-lox knockout of both APC and MYC [GeneID=324;4609] in small intestine."} {"geneset":"SANSOM_APC_TARGETS_REQUIRE_MYC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANSOM_APC_TARGETS_REQUIRE_MYC","description":"Genes up-regulated after Cre-lox knockout of APC [GeneID=324] in the small intestine that require functional MYC [GeneID=4609]."} {"geneset":"SANSOM_WNT_PATHWAY_REQUIRE_MYC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANSOM_WNT_PATHWAY_REQUIRE_MYC","description":"Wnt target genes up-regulated after Cre-lox knockout of APC [GeneID=324] in the small intestine that require functional MYC [GeneID=4609]."} {"geneset":"YEGNASUBRAMANIAN_PROSTATE_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YEGNASUBRAMANIAN_PROSTATE_CANCER","description":"Genes expressed in at least one prostate cancer cell line but not in normal prostate epithelial cells or stromal cells"} {"geneset":"RIGGINS_TAMOXIFEN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIGGINS_TAMOXIFEN_RESISTANCE_UP","description":"Genes up-regulated SUM44/LCCTam cells (breast cancer) resistant to 4-hydroxytamoxifen [PubChem=63062] relative to the parental SUM44 cells sensitive to the drug."} {"geneset":"RIGGINS_TAMOXIFEN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIGGINS_TAMOXIFEN_RESISTANCE_DN","description":"Genes down-regulated SUM44/LCCTam cells (breast cancer) resistant to 4-hydroxytamoxifen [PubChem=63062] relative to the parental SUM44 cells sensitive to the drug."} {"geneset":"NIKOLSKY_OVERCONNECTED_IN_BREAST_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIKOLSKY_OVERCONNECTED_IN_BREAST_CANCER","description":"Overconnected mutated transcription factors regulating genes within the breast cancer amplicome."} {"geneset":"STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_UP","description":"Genes up-regulated by estradiol [PubChem=5757] and up-regulated by ESRRA [GeneID=2101] in MCF-7 cells (breast cancer)."} {"geneset":"STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN","description":"Genes down-regulated by estradiol [PubChem=5757] and down-regulated by ESRRA [GeneID=2101] in MCF-7 cells (breast cancer)."} {"geneset":"STEIN_ESRRA_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEIN_ESRRA_TARGETS_UP","description":"Genes up-regulated by ESRRA [GeneID=2101] only."} {"geneset":"STEIN_ESRRA_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEIN_ESRRA_TARGETS_DN","description":"Genes down-regulated by ESRRA [GeneID=2101] only."} {"geneset":"WANG_LSD1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_LSD1_TARGETS_UP","description":"Genes up-regulated after Cre-lox knockout of LSD1 [GeneID=23028] in pituitary."} {"geneset":"WANG_LSD1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_LSD1_TARGETS_DN","description":"Genes down-regulated after Cre-lox knockout of LSD1 [GeneID=23028] in pituitary."} {"geneset":"FOSTER_TOLERANT_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOSTER_TOLERANT_MACROPHAGE_UP","description":"Class T (tolerizeable) genes: induced during the first LPS stimulation and either not re-induced or induced to a much lesser degree in tolerant macrophages."} {"geneset":"FOSTER_TOLERANT_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOSTER_TOLERANT_MACROPHAGE_DN","description":"Class NT (non-tolerizeable) genes: induced during the first LPS stimulation and induced at equal or greater degree in tolerant macrophages."} {"geneset":"TESAR_ALK_TARGETS_EPISC_3D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_ALK_TARGETS_EPISC_3D_UP","description":"Genes up-regulated in EpiSC cells (mouse epiblast embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]."} {"geneset":"TESAR_ALK_TARGETS_EPISC_4D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_ALK_TARGETS_EPISC_4D_UP","description":"Genes up-regulated in EpiSC cells (epiblast stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]."} {"geneset":"TESAR_ALK_AND_JAK_TARGETS_MOUSE_ES_D4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_ALK_AND_JAK_TARGETS_MOUSE_ES_D4_UP","description":"Genes up-regulated in mES cells (mouse embryonic stem cells) after tratment with the ALK [GeneID=238] inhibitor SB-431542 and JAK inhibitor I [PubChem=4521392;5494425]."} {"geneset":"TESAR_ALK_AND_JAK_TARGETS_MOUSE_ES_D4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_ALK_AND_JAK_TARGETS_MOUSE_ES_D4_DN","description":"Genes down-regulated in mES cells (mouse embryonic stem cells) after tratment with the ALK [GeneID=238] inhibitor SB-431542 and JAK inhibitor I [PubChem=4521392;5494425]."} {"geneset":"TESAR_JAK_TARGETS_MOUSE_ES_D3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_JAK_TARGETS_MOUSE_ES_D3_UP","description":"Genes up-regulated in mES cells (mouse embryonic stem cells) after tratment with JAK inhibitor I [PubChem=5494425]."} {"geneset":"TESAR_JAK_TARGETS_MOUSE_ES_D3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TESAR_JAK_TARGETS_MOUSE_ES_D3_DN","description":"Genes down-regulated in mES cells (mouse embryonic stem cells) after tratment with JAK inhibitor I [PubChem=5494425]."} {"geneset":"JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN","description":"Cluster B: genes down-regulated in primary lung tumors driven by KRAS [GeneID=3845] activation and loss of STK11 [GeneID=6794]; also up-regulated in human squamous cell carcinoma (SCC) vs adenocarcinoma subtype of NSCLC (non-small cell lung cancer)."} {"geneset":"JI_CARCINOGENESIS_BY_KRAS_AND_STK11_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JI_CARCINOGENESIS_BY_KRAS_AND_STK11_UP","description":"Cluster A: genes up-regulated in primary lung tumors driven by KRAS [GeneID=3845] activation and loss of STK11 [GeneID=6794]; also up-regulated in human squamous cell carcinoma (SCC) vs adenocarcinoma subtype of NSCLC (non-small cell lung cancer)."} {"geneset":"GAZIN_EPIGENETIC_SILENCING_BY_KRAS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAZIN_EPIGENETIC_SILENCING_BY_KRAS","description":"Genes required for epigenetic silencing of FAS [GeneID=355] by activated KRAS [GeneID=3845] in NIH 3T3 cells, based on RNAi screen."} {"geneset":"JEPSEN_SMRT_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JEPSEN_SMRT_TARGETS","description":"Genes up-regulated in neural progenitor cells (NPC) isolated from E13 cortical tissue of SMRT [GeneID=9612] knockout mice."} {"geneset":"KYNG_DNA_DAMAGE_BY_4NQO","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_DNA_DAMAGE_BY_4NQO","description":"Genes specifically responding to 4NQO treatment of primary fibroblasts."} {"geneset":"KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION","description":"Genes specifically responding to gamma radiation."} {"geneset":"KYNG_DNA_DAMAGE_BY_UV","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_DNA_DAMAGE_BY_UV","description":"UV only responding genes in primary fibroblasts from young donors."} {"geneset":"KYNG_DNA_DAMAGE_BY_4NQO_OR_GAMMA_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_DNA_DAMAGE_BY_4NQO_OR_GAMMA_RADIATION","description":"Genes responding to 4NQO treatment and gamma irradiation."} {"geneset":"KYNG_DNA_DAMAGE_BY_4NQO_OR_UV","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_DNA_DAMAGE_BY_4NQO_OR_UV","description":"4NQO treatment and UV irradiation responding genes."} {"geneset":"KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION","description":"Gamma and UV responding genes."} {"geneset":"KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_OLD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_OLD","description":"Human environmental etress response genes not changed in primary fibroblasts from old donors in response to 4NQO treatment."} {"geneset":"KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_WS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_WS","description":"Human environmental stress response genes not changed in primary fibroblasts from Wilmor syndrom (WS) patients in response to 4NQO treatment."} {"geneset":"KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_OLD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_OLD","description":"Human environmental stress response (H-ESR) genes not changed in primary fibroblasts from old donors in response to gamma radiation."} {"geneset":"KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS","description":"Human environmental stress response genes not changed in primary fibroblasts from Werner syndrom (WS) patients in response to gamma radiation."} {"geneset":"KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_UV_IN_OLD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_UV_IN_OLD","description":"Human environmental stress response genes not changed in primary fibroblasts from old donors in response to UV radiation."} {"geneset":"KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_UV_IN_WS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_UV_IN_WS","description":"Human environmental stress response genes not changed in primary fibroblasts from patients with Warner syndrom (WS) ."} {"geneset":"KYNG_DNA_DAMAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_DNA_DAMAGE_DN","description":"Genes with GO annotation and down-regulated after DNA damage in cell lines from young donors."} {"geneset":"KYNG_DNA_DAMAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_DNA_DAMAGE_UP","description":"Genes with GO annotation and up-regulated after DNA damage in cell lines from young donors."} {"geneset":"KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP","description":"All common up-regulated stress response genes (Human Environmental Stress Response, H-ESR)."} {"geneset":"KYNG_ENVIRONMENTAL_STRESS_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_ENVIRONMENTAL_STRESS_RESPONSE_DN","description":"All common down-regulated stress response genes (Human Environmental Stress Response, H-ESR)."} {"geneset":"KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3","description":"Genes with high histone H3 trimethylation mark at K27 (H3K27me3) in PC3 cells (prostate cancer) by ChIP-chip assay on a 12K CpG array (high-CpG-density promoters, HCP)."} {"geneset":"KONDO_PROSTATE_CANCER_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KONDO_PROSTATE_CANCER_WITH_H3K27ME3","description":"Top 200 genes with high histone H3 trimethylation mark at K27 (H3K27me3) in PC3 cells (prostate cancer), by ChIP-chip assay on an 88K microarray (all promoters)."} {"geneset":"KONDO_COLON_CANCER_HCP_WITH_H3K27ME1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KONDO_COLON_CANCER_HCP_WITH_H3K27ME1","description":"Genes with high levels of histone H3 monomethylation mark at K27 (H3K27me1) in SW48 cells (colon cancer) by ChIP-chip assay on a 12K CpG array (CpG promoters only, HCP=high-CpG-density promoters)."} {"geneset":"KONDO_COLON_CANCER_HCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KONDO_COLON_CANCER_HCP_WITH_H3K27ME3","description":"Genes with high histone H3 tri-methylation mark at K27 (H3K27me3) in SW48 cells (colon cancer), by ChIP-chip assay on a 12K CpG array (high-CpG-density promoters, HCP)."} {"geneset":"KONDO_EZH2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KONDO_EZH2_TARGETS","description":"Genes up-regulated in PC3 cells (prostate cancer) after EZH2 [GeneID=2146] knockdown by RNAi."} {"geneset":"LEE_LIVER_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER","description":"Genes down-regulated in tumor compared to non-tumor liver samples from patients with hepatocellular carcinoma (HCC)."} {"geneset":"ZHANG_GATA6_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_GATA6_TARGETS_UP","description":"Genes up-regulated after cre-lox knockout of GATA6 [GeneID=2627] in airway epithelium."} {"geneset":"ZHANG_GATA6_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_GATA6_TARGETS_DN","description":"Genes down-regulated after cre-lox knockout of GATA6 [GeneID=2627] in airway epithelium."} {"geneset":"MCGOWAN_RSP6_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCGOWAN_RSP6_TARGETS_UP","description":"Genes up-regulated by hemizygotic cre-lox knockout of RSP6 [GeneID=81492] in keratinocytes."} {"geneset":"MCGOWAN_RSP6_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCGOWAN_RSP6_TARGETS_DN","description":"Genes down-regulated by hemizygotic cre-lox knockout of RSP6 [GeneID=81492] in keratinocytes."} {"geneset":"KANG_CISPLATIN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_CISPLATIN_RESISTANCE_UP","description":"Genes up-regulated in gastric cancer cell lines resistant to cisplatin [PubChem=2767]."} {"geneset":"KANG_CISPLATIN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_CISPLATIN_RESISTANCE_DN","description":"Genes down-regulated in gastric cancer cell lines resistant to cisplatin [PubChem=2767]."} {"geneset":"STEARMAN_TUMOR_FIELD_EFFECT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEARMAN_TUMOR_FIELD_EFFECT_UP","description":"Up-regulated genes in the 'Field Effect' signature of normal lung tissue adjacent to the tumor."} {"geneset":"STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP","description":"Up-regulated genes classifying non-tumor lung tissues by age after incution of lung cancer by urethane injection [PubChem=5641]: early (24-26 weeks) vs late (46 weeks)."} {"geneset":"STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN","description":"Down-regulated genes classifying non-tumor lung tissues by age after incution of lung cancer by urethane injection [PubChem=5641]: early (24-26 weeks) vs late (46 weeks)."} {"geneset":"HELLER_SILENCED_BY_METHYLATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HELLER_SILENCED_BY_METHYLATION_UP","description":"Genes up-regulated in at least one of three multiple myeloma (MM) cell lines treated with the DNA hypomethylating agent decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]."} {"geneset":"HELLER_SILENCED_BY_METHYLATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HELLER_SILENCED_BY_METHYLATION_DN","description":"Genes down-regulated in at least one of three multiple myeloma (MM) cell lines treated with the DNA hypomethylating agent decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]."} {"geneset":"HELLER_HDAC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HELLER_HDAC_TARGETS_UP","description":"Genes up-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]."} {"geneset":"HELLER_HDAC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HELLER_HDAC_TARGETS_DN","description":"Genes down-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]."} {"geneset":"HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP","description":"Genes up-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]."} {"geneset":"HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN","description":"Genes down-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]."} {"geneset":"CLAUS_PGR_POSITIVE_MENINGIOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CLAUS_PGR_POSITIVE_MENINGIOMA_UP","description":"Genes up-regulated in meningioma samples positive for PGR [GeneID=5241] compared to those without the receptor."} {"geneset":"CLAUS_PGR_POSITIVE_MENINGIOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CLAUS_PGR_POSITIVE_MENINGIOMA_DN","description":"Genes down-regulated in meningioma samples positive for PGR [GeneID=5241] compared to those without the receptor."} {"geneset":"WONG_MITOCHONDRIA_GENE_MODULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_MITOCHONDRIA_GENE_MODULE","description":"Genes that comprise the mitochondria gene module"} {"geneset":"WONG_PROTEASOME_GENE_MODULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_PROTEASOME_GENE_MODULE","description":"Genes that comprise the proteasome gene module"} {"geneset":"AMUNDSON_GAMMA_RADIATION_RESISTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMUNDSON_GAMMA_RADIATION_RESISTANCE","description":"Gene predicting resistance of the NCI-60 cell lines to gamma radiation."} {"geneset":"AMUNDSON_GAMMA_RADIATION_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMUNDSON_GAMMA_RADIATION_RESPONSE","description":"Genes down-regulated across the entire panel of NCI-60 cell lines in response to gamma radiation."} {"geneset":"AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G","description":"Genes with basal expression distinguishing NCI-60 cell lines with poor survival after 8 Gy gamma irradiation."} {"geneset":"AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G","description":"Genes with basal expression distinguishing NCI-60 cell lines with poor survival after 2 Gy gamma irradiation."} {"geneset":"COATES_MACROPHAGE_M1_VS_M2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COATES_MACROPHAGE_M1_VS_M2_UP","description":"Up-regulated genes distinguishing between M1 (pro-inflammatory) and M2 (anti-inflammatory) macrophage subtypes."} {"geneset":"COATES_MACROPHAGE_M1_VS_M2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COATES_MACROPHAGE_M1_VS_M2_DN","description":"Down-regulated genes distinguishing between M1 (pro-inflammatory) and M2 (anti-inflammatory) macrophage subtypes."} {"geneset":"LEE_METASTASIS_AND_RNA_PROCESSING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_METASTASIS_AND_RNA_PROCESSING_UP","description":"Components of RNA post-transcriptional modification machinery up-regulated in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [GeneID=4830]."} {"geneset":"LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP","description":"Up-regulated genes displaying alternative splicing in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [GeneID=4830]."} {"geneset":"LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_DN","description":"Down-regulated genes displaying alternative splicing in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [GeneID=4830]."} {"geneset":"LIN_MELANOMA_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIN_MELANOMA_COPY_NUMBER_UP","description":"Candidate genes in significant regions of chromosomal copy number gains in a panel of melanoma samples."} {"geneset":"LIN_MELANOMA_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIN_MELANOMA_COPY_NUMBER_DN","description":"Candidate genes in significant regions of chromosomal copy number losses in a panel of melanoma samples."} {"geneset":"MARTINEZ_RB1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_RB1_TARGETS_UP","description":"Genes up-regulated in mice with skin specific knockout of RB1 [GeneID=5925] by Cre-lox."} {"geneset":"MARTINEZ_RB1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_RB1_TARGETS_DN","description":"Genes down-regulated in mice with skin specific knockout of RB1 [GeneID=5925] by Cre-lox."} {"geneset":"MARTINEZ_TP53_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_TP53_TARGETS_UP","description":"Genes up-regulated in mice with skin specific knockout of TP53 [GeneID=7157]."} {"geneset":"MARTINEZ_TP53_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_TP53_TARGETS_DN","description":"Genes down-regulated in mice with skin specific knockout of TP53 [GeneID=7157]."} {"geneset":"MARTINEZ_RB1_AND_TP53_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_RB1_AND_TP53_TARGETS_UP","description":"Genes up-regulated in mice with skin specific double knockout of both RB1 and TP53 [GeneID=5925;7157] by Cre-lox."} {"geneset":"MARTINEZ_RB1_AND_TP53_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINEZ_RB1_AND_TP53_TARGETS_DN","description":"Genes down-regulated in mice with skin specific double knockout of both RB1 and TP53 [GeneID=5925;7157] by Cre-lox."} {"geneset":"FINETTI_BREAST_CANCER_KINOME_RED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FINETTI_BREAST_CANCER_KINOME_RED","description":"Genes in the red cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes."} {"geneset":"FINETTI_BREAST_CANCER_KINOME_GREEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FINETTI_BREAST_CANCER_KINOME_GREEN","description":"Genes in the green cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes."} {"geneset":"FINETTI_BREAST_CANCERS_KINOME_BLUE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FINETTI_BREAST_CANCERS_KINOME_BLUE","description":"Genes in the blue cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes."} {"geneset":"FINETTI_BREAST_CANCERS_KINOME_GRAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FINETTI_BREAST_CANCERS_KINOME_GRAY","description":"Genes in the gray cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes."} {"geneset":"MASSARWEH_TAMOXIFEN_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MASSARWEH_TAMOXIFEN_RESISTANCE_UP","description":"Genes up-regulated in breast cancer tumors (formed by MCF-7 xenografts) resistant to tamoxifen [PubChem=5376]."} {"geneset":"MASSARWEH_TAMOXIFEN_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MASSARWEH_TAMOXIFEN_RESISTANCE_DN","description":"Genes down-regulated in breast cancer tumors (formed by MCF-7 xenografts) resistant to tamoxifen [PubChem=5376]."} {"geneset":"MASSARWEH_RESPONSE_TO_ESTRADIOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MASSARWEH_RESPONSE_TO_ESTRADIOL","description":"Genes rapidly up-regulated in breast cancer cell cultures by estradiol [PubChem=5757]."} {"geneset":"WALLACE_PROSTATE_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WALLACE_PROSTATE_CANCER_UP","description":"Genes up-regulated in prostate tumor vs normal tissue samples."} {"geneset":"WALLACE_PROSTATE_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WALLACE_PROSTATE_CANCER_DN","description":"Genes down-regulated in prostate tumor vs normal tissue samples."} {"geneset":"WALLACE_PROSTATE_CANCER_RACE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WALLACE_PROSTATE_CANCER_RACE_UP","description":"Genes up-regulated in prostate cancer samples from African-American patients compared to those from the European-American patients."} {"geneset":"WALLACE_PROSTATE_CANCER_RACE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WALLACE_PROSTATE_CANCER_RACE_DN","description":"Genes down-regulated in prostate cancer samples from African-American patients compared to those from the European-American patients."} {"geneset":"SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP","description":"Genes up-regulated in MCF10A cells (breast cancer) grown at low (mesenchymal phenotype) compared to those grown at high (epithelial, basal-like phenotype) confluency."} {"geneset":"SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN","description":"Genes down-regulated in MCF10A cells (breast cancer) grown at low (mesenchymal phenotype) compared to those grown at high (epithelial, basal-like phenotype) confluency."} {"geneset":"OUILLETTE_CLL_13Q14_DELETION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUILLETTE_CLL_13Q14_DELETION_UP","description":"Genes up-regulated in chronic lymphocytic leukemia (CLL) samples bearing deletions in the 13q14 region."} {"geneset":"OUILLETTE_CLL_13Q14_DELETION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUILLETTE_CLL_13Q14_DELETION_DN","description":"Genes down-regulated in chronic lymphocytic leukemia (CLL) samples bearing deletions in the 13q14 region."} {"geneset":"YOKOE_CANCER_TESTIS_ANTIGENS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YOKOE_CANCER_TESTIS_ANTIGENS","description":"Genes up-regulated in both colorectal cancer cells and normal testis relative to normal colon epithelium."} {"geneset":"MARZEC_IL2_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARZEC_IL2_SIGNALING_UP","description":"Genes up-regulated by IL2 [GeneID=3558] in cells derived from CD4+ [GeneID=920] cutaneous T-cell lymphoma (CTCL)."} {"geneset":"MARZEC_IL2_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARZEC_IL2_SIGNALING_DN","description":"Genes down-regulated by IL2 [GeneID=3558] in cells derived from CD4+ [GeneID=920] cutaneous T-cell lymphoma (CTCL)."} {"geneset":"IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_UP","description":"Cluster 1: genes up-regulated in lung tissue samples from mice with oncogenic form of KRAS [GeneID=3845] and inactivated PTEN [GeneID=5728]."} {"geneset":"IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN","description":"Cluster 2: genes down-regulated in lung tissue samples from mice with oncogenic form of KRAS [GeneID=3845] and inactivated PTEN [GeneID=5728]."} {"geneset":"IWANAGA_CARCINOGENESIS_BY_KRAS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IWANAGA_CARCINOGENESIS_BY_KRAS_UP","description":"Cluster 3: genes up-regulated in lung tissue samples from mice with tumor-bearing genotypes (activated KRAS [GeneID=3845] alone or together with inactivated PTEN [GeneID=5728])."} {"geneset":"IWANAGA_CARCINOGENESIS_BY_KRAS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IWANAGA_CARCINOGENESIS_BY_KRAS_DN","description":"Cluster 4: genes down-regulated in lung tissue samples from mice with tumor-bearing genotypes (activated KRAS [GeneID=3845] alone or together with inactivated PTEN [GeneID=5728])."} {"geneset":"DER_IFN_ALPHA_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DER_IFN_ALPHA_RESPONSE_DN","description":"Genes down-regulated in HT1080 cells (fibrosarcoma) by treatment with interferon alpha for 6 h."} {"geneset":"CAMPS_COLON_CANCER_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAMPS_COLON_CANCER_COPY_NUMBER_UP","description":"Genes from chromosomal copy number gains in a panel of 51 primary colon carcinoma samples."} {"geneset":"CAMPS_COLON_CANCER_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAMPS_COLON_CANCER_COPY_NUMBER_DN","description":"Genes from chromosomal copy number losses in a panel of 51 primary colon carcinoma samples."} {"geneset":"RIZKI_TUMOR_INVASIVENESS_3D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZKI_TUMOR_INVASIVENESS_3D_UP","description":"Genes up-regulated in three-dimentional (3D) cultures of preinvasive (S3-C) vs invasive (T4-2) breast cancer cells."} {"geneset":"RIZKI_TUMOR_INVASIVENESS_3D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZKI_TUMOR_INVASIVENESS_3D_DN","description":"Genes down-regulated in three-dimentional (3D) cultures of preinvasive (S3-C) vs invasive (T4-2) breast cancer cells."} {"geneset":"RIZKI_TUMOR_INVASIVENESS_2D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZKI_TUMOR_INVASIVENESS_2D_UP","description":"Genes up-regulated in monolayer (2D) cultures of preinvasive (S3-C) vs invasive (T4-2) breast cancer cells."} {"geneset":"RIZKI_TUMOR_INVASIVENESS_2D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIZKI_TUMOR_INVASIVENESS_2D_DN","description":"Genes down-regulated in monolayer (2D) cultures of preinvasive (S3-C) vs invasive (T4-2) breast cancer cells."} {"geneset":"FUJII_YBX1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUJII_YBX1_TARGETS_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [GeneID=4904] by RNAi."} {"geneset":"FUJII_YBX1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUJII_YBX1_TARGETS_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [GeneID=4904] by RNAi."} {"geneset":"OSADA_ASCL1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OSADA_ASCL1_TARGETS_UP","description":"Genes up-regulated in A549 cells (lung cancer) upon expression of ASCL1 [GeneID=429] off a viral vector."} {"geneset":"OSADA_ASCL1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OSADA_ASCL1_TARGETS_DN","description":"Genes down-regulated in A549 cells (lung cancer) upon expression of ASCL1 [GeneID=429] off a viral vector."} {"geneset":"CHENG_IMPRINTED_BY_ESTRADIOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHENG_IMPRINTED_BY_ESTRADIOL","description":"Genes whose CpG islands became hypermethylated in breast progenitor cells pre-exposed to estradiol [PubChem=5757]."} {"geneset":"DE_YY1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DE_YY1_TARGETS_UP","description":"Genes up-regulated in SaOS-2 cells (osteosarcoma) upon knockdown of YY1 [GeneID=7528] by RNAi."} {"geneset":"DE_YY1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DE_YY1_TARGETS_DN","description":"Genes down-regulated in SaOS-2 cells (osteosarcoma) upon knockdown of YY1 [GeneID=7528] by RNAi."} {"geneset":"BIERIE_INFLAMMATORY_RESPONSE_TGFB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BIERIE_INFLAMMATORY_RESPONSE_TGFB1","description":"Inflammatory genes down-regulated in mammary carcinoma cells after stimulation with TGFB1 [GeneID=7040] for 1 hr."} {"geneset":"MCCABE_BOUND_BY_HOXC6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCABE_BOUND_BY_HOXC6","description":"Genes whose promoters where bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer), according to a ChIP-chip analysis."} {"geneset":"POS_RESPONSE_TO_HISTAMINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POS_RESPONSE_TO_HISTAMINE_UP","description":"Genes gradually up-regulated by histamine [PubChem=774] in B16-F10 melanoma tumors."} {"geneset":"POS_RESPONSE_TO_HISTAMINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POS_RESPONSE_TO_HISTAMINE_DN","description":"Genes gradually down-regulated by histamine [PubChem=774] in B16-F10 melanoma tumors."} {"geneset":"POS_HISTAMINE_RESPONSE_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POS_HISTAMINE_RESPONSE_NETWORK","description":"Genes corresponding to the histamine [PubChem=774] response network."} {"geneset":"DAIRKEE_CANCER_PRONE_RESPONSE_E2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAIRKEE_CANCER_PRONE_RESPONSE_E2","description":"'Cancer prone response profile' (CPRP): genes changed in response to estradiol [PubChem=5757] in epithelial cell cultures from patients at high risk of breast cancer."} {"geneset":"DAIRKEE_CANCER_PRONE_RESPONSE_BPA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAIRKEE_CANCER_PRONE_RESPONSE_BPA","description":"'Cancer prone response profile' (CPRP): genes changed in response to bisphenol A [PubChem=6623] in epithelial cell cultures from patients at high risk of breast cancer."} {"geneset":"DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2","description":"'Cancer prone response profile' (CPRP): genes common to estradiol and bisphenol A [PubChem=5757;6623] response of epithelial cell cultures from patients at high risk of breast cancer."} {"geneset":"YAMASHITA_SILENCED_BY_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMASHITA_SILENCED_BY_METHYLATION","description":"Genes silenced by DNA methylation in prostate cancer cell lines."} {"geneset":"YAMASHITA_METHYLATED_IN_PROSTATE_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMASHITA_METHYLATED_IN_PROSTATE_CANCER","description":"Genes up-regulated in prostate cancer cell lines after treatment with 5-aza-2'-deoxycytidine (decitabine) [PubChem=451668]."} {"geneset":"OUYANG_PROSTATE_CANCER_PROGRESSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUYANG_PROSTATE_CANCER_PROGRESSION_UP","description":"Genes up-regulated during prostate cancer progression in mice heterozygotic for both NKX3.1 and PTEN [GeneID=4824;5728]."} {"geneset":"OUYANG_PROSTATE_CANCER_PROGRESSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUYANG_PROSTATE_CANCER_PROGRESSION_DN","description":"Genes down-regulated during prostate cancer progression in mice heterozygotic for both NKX3.1 and PTEN [GeneID=4824;5728]."} {"geneset":"OUYANG_PROSTATE_CANCER_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OUYANG_PROSTATE_CANCER_MARKERS","description":"Mouse orthologs of human prostate cancer tumor markers which were deregulated in mice heterozygotic for both NKX3.1 and PTEN [GeneID=4824;5728]."} {"geneset":"RIGGI_EWING_SARCOMA_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIGGI_EWING_SARCOMA_PROGENITOR_UP","description":"Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein."} {"geneset":"RIGGI_EWING_SARCOMA_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RIGGI_EWING_SARCOMA_PROGENITOR_DN","description":"Genes down-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein."} {"geneset":"GAUTSCHI_SRC_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAUTSCHI_SRC_SIGNALING","description":"Genes down-regulated in A549 cells (lung cancer) after treatment with AZD0530 [PubChem=10302451], a SRC [GeneID=6714] kinase inhibitor."} {"geneset":"VICENT_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VICENT_METASTASIS_UP","description":"The metastasis gene signature: genes up-regulated during metastasis of NSCLC (non-small cell lung carcinoma) tumors to bone."} {"geneset":"AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53","description":"Genes down-regulated by flavopiridol [PubChem=5287969] in the HCT116 cells (colon cancer) depending on their TP53 [GeneID=7157] status: wild-type vs loss of the gene's function (LOF)."} {"geneset":"HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP","description":"Genes up-regulated in SCLC (small cell lung cancer) cells with acquired resistance to ABT-737 [PubChem=11228183], an inhibitor of the BCL2 [GeneID=596] family proteins."} {"geneset":"HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN","description":"Genes down-regulated in SCLC (small cell lung cancer) cells with acquired resistance to ABT-737 [PubChem=11228183], an inhibitor of the BCL2 [GeneID=596] family proteins."} {"geneset":"ENGELMANN_CANCER_PROGENITORS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ENGELMANN_CANCER_PROGENITORS_UP","description":"Up-regulated genes in the cancer progenitor (stem) cells corresponding to side population (SP) MCF7 cells (breast cancer) positive for MUC1 [GeneID=4582]."} {"geneset":"ENGELMANN_CANCER_PROGENITORS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ENGELMANN_CANCER_PROGENITORS_DN","description":"Down-regulated genes in the cancer progenitor (stem) cells corresponding to side population (SP) MCF7 cells (breast cancer) positive for MUC1 [GeneID=4582]."} {"geneset":"WORSCHECH_TUMOR_REJECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WORSCHECH_TUMOR_REJECTION_UP","description":"Up-regulated genes defining rejection of mammary carcinoma (MMC) tumors."} {"geneset":"WORSCHECH_TUMOR_REJECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WORSCHECH_TUMOR_REJECTION_DN","description":"Down-regulated genes defining rejection of mammary carcinoma (MMC) tumors."} {"geneset":"HUANG_FOXA2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUANG_FOXA2_TARGETS_UP","description":"Genes up-regulated in H358 cells (lung cancer) by inducible expression of FOXA2 [GeneID=3170] in a Tet-off system."} {"geneset":"HUANG_FOXA2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUANG_FOXA2_TARGETS_DN","description":"Genes down-regulated in H358 cells (lung cancer) by inducible expression of FOXA2 [GeneID=3170] in a Tet-off system."} {"geneset":"MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP","description":"Genes up-regulated in derivatives of MCF-7aro cells (breast cancer) that developed resistance to tamoxifen [PubChem=5376] or inhibitors of aromatase (CYP19A1) [GeneID=1588]."} {"geneset":"MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN","description":"Genes down-regulated in derivatives of MCF-7aro cells (breast cancer) that developed resistance to tamoxifen [PubChem=5376] or inhibitors of aromatase (CYP19A1) [GeneID=1588]."} {"geneset":"MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP","description":"Top genes up-regulated in mesenchyme stem cells (MSC) grown in a tumor conditioned medium, which leads to carcinoma-associated fibroblast phenotype."} {"geneset":"MCCABE_HOXC6_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCABE_HOXC6_TARGETS_UP","description":"Genes with promoters bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer) and up-regulated upon loss of function (LOF) of HOXC6."} {"geneset":"MCCABE_HOXC6_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCABE_HOXC6_TARGETS_DN","description":"Genes with promoters bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer) and down-regulated upon loss of function (LOF) of HOXC6."} {"geneset":"TING_SILENCED_BY_DICER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TING_SILENCED_BY_DICER","description":"Epigenetically silenced genes up-regulated in HCT116 cells (colon cancer) hypomorphic for DICER1 [GeneID=23405]."} {"geneset":"BOYERINAS_ONCOFETAL_TARGETS_OF_LET7A1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYERINAS_ONCOFETAL_TARGETS_OF_LET7A1","description":"Embryonic genes targeted by LET7A1 [GeneID=406881] and which are up-regulated in many human cancers."} {"geneset":"MCCABE_HOXC6_TARGETS_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCABE_HOXC6_TARGETS_CANCER_UP","description":"Genes whose promoters were bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer) and which were up-regulated in comparison of tumor vs normal prostate tissue samples."} {"geneset":"MCCABE_HOXC6_TARGETS_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCCABE_HOXC6_TARGETS_CANCER_DN","description":"Genes whose promoters were bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer) and which were down-regulated in comparison of tumor vs normal prostate tissue samples."} {"geneset":"MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_UP","description":"Genes commonly up-regulated in SK-N-BE cells (neuroblastoma) after RNAi knockdown of CCND1 and CDK4 [GeneID=595;1019]."} {"geneset":"MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN","description":"Genes commonly down-regulated in SK-N-BE cells (neuroblastoma) after RNAi knockdown of CCND1 and CDK4 [GeneID=595;1019]."} {"geneset":"ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP","description":"Genes up-regulated in normal tissue adjacent to liver tumor, compared to the normal liver samples."} {"geneset":"ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN","description":"Genes down-regulated in normal tissue adjacent to liver tumor, compared to the normal liver samples."} {"geneset":"ACEVEDO_LIVER_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_LIVER_CANCER_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) compared to normal liver samples."} {"geneset":"ACEVEDO_LIVER_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_LIVER_CANCER_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) compared to normal liver samples."} {"geneset":"ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP","description":"Genes up-regulated in liver tumor compared to the normal adjacent tissue."} {"geneset":"ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN","description":"Genes down-regulated in liver tumor compared to the normal adjacent tissue."} {"geneset":"ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP","description":"Genes whose promoters display higher levels of histone H3 trimethylation mark at K27 (H3K27me3) in hepatocellular carcinoma (HCC) compared to normal liver."} {"geneset":"ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN","description":"Genes whose promoters display lower levels of histone H3 trimethylation mark at K27 (H3K27me3) in hepatocellular carcinoma (HCC) compared to normal liver."} {"geneset":"ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_UP","description":"Genes whose promoters display higher histone H3 trimethylation mark at K9 (H3K9me3) in hepatocellular carcinoma (HCC) compared to normal liver."} {"geneset":"ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN","description":"Genes whose promoters display lower histone H3 trimethylation mark at K9 (H3K9me3) in hepatocellular carcinoma (HCC) compared to normal liver."} {"geneset":"ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN","description":"Genes whose DNA is hypo-methylated in hepatocellular carcinoma (HCC) compared to normal liver."} {"geneset":"MITSIADES_RESPONSE_TO_APLIDIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MITSIADES_RESPONSE_TO_APLIDIN_UP","description":"Genes up-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164], a marine-derived compound with potential anti-cancer properties."} {"geneset":"MITSIADES_RESPONSE_TO_APLIDIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MITSIADES_RESPONSE_TO_APLIDIN_DN","description":"Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164], a marine-derived compound with potential anti-cancer properties."} {"geneset":"HOQUE_METHYLATED_IN_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOQUE_METHYLATED_IN_CANCER","description":"Genes whose DNA was methylated both in primary tumors and across a panel of cancer cell lines."} {"geneset":"NADELLA_PRKAR1A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NADELLA_PRKAR1A_TARGETS_UP","description":"Epithelial and mesenchymal markers up-regulated in MEF cells (embryonic fibroblasts) after knockout of PRKAR1A [GeneID=5573]."} {"geneset":"NADELLA_PRKAR1A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NADELLA_PRKAR1A_TARGETS_DN","description":"Epithelial and mesenchymal markers down-regulated in MEF cells (embryonic fibroblasts) after knockout of PRKAR1A [GeneID=5573]."} {"geneset":"SAGIV_CD24_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAGIV_CD24_TARGETS_UP","description":"Genes up-regulated in HT29 cells (colon cancer) after knockdown of CD24 [GeneID=100133941] by both RNAi and monoclonal antibodies."} {"geneset":"SAGIV_CD24_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAGIV_CD24_TARGETS_DN","description":"Genes down-regulated in HT29 cells (colon cancer) after knockdown of CD24 [GeneID=100133941] by both RNAi and monoclonal antibodies."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_UP","description":"Genes up-regulated in brain relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN","description":"Genes down-regulated in brain relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP","description":"Genes up-regulated in bone relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN","description":"Genes down-regulated in bone relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP","description":"Genes up-regulated in lung relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_LUNG_DN","description":"Genes down-regulated in lung relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_LIVER_UP","description":"Genes up-regulated in liver relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN","description":"Genes down-regulated in liver relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_UP","description":"Genes up-regulated in pleura relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_DN","description":"Genes down-regulated in pleura relapse of breast cancer."} {"geneset":"SMID_BREAST_CANCER_LUMINAL_B_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_LUMINAL_B_UP","description":"Genes up-regulated in the luminal B subtype of breast cancer."} {"geneset":"SMID_BREAST_CANCER_LUMINAL_B_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_LUMINAL_B_DN","description":"Genes down-regulated in the luminal B subtype of breast cancer."} {"geneset":"SMID_BREAST_CANCER_LUMINAL_A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_LUMINAL_A_UP","description":"Genes up-regulated in the luminal A subtype of breast cancer."} {"geneset":"SMID_BREAST_CANCER_LUMINAL_A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_LUMINAL_A_DN","description":"Genes down-regulated in the luminal A subtype of breast cancer."} {"geneset":"SMID_BREAST_CANCER_ERBB2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_ERBB2_UP","description":"Genes up-regulated in the erbb2 subype of breast cancer samples, characterized by higher expression of ERBB2 [GeneID=2064]."} {"geneset":"SMID_BREAST_CANCER_ERBB2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_ERBB2_DN","description":"Genes down-regulated in the erbb2 subype of breast cancer samples, characterized by higher expression of ERBB2 [GeneID=2064]."} {"geneset":"SMID_BREAST_CANCER_NORMAL_LIKE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_NORMAL_LIKE_UP","description":"Genes up-regulated in the normal-like subtype of breast cancer."} {"geneset":"SMID_BREAST_CANCER_NORMAL_LIKE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_NORMAL_LIKE_DN","description":"Genes down-regulated in the normal-like subtype of breast cancer."} {"geneset":"SMID_BREAST_CANCER_BASAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_BASAL_UP","description":"Genes up-regulated in basal subtype of breast cancer samles."} {"geneset":"SMID_BREAST_CANCER_BASAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMID_BREAST_CANCER_BASAL_DN","description":"Genes down-regulated in basal subtype of breast cancer samles."} {"geneset":"KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP","description":"Genes up-regulated in response to nutlin-3a [PubChem=216345], an inhibitor of MDM2 [GeneID=4193], in skin fibroblast cultures after knockdown of TP53 [GeneID=7157] by RNAi."} {"geneset":"KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN","description":"Genes down-regulated in response to nutlin-3a [PubChem=216345], an inhibitor of MDM2 [GeneID=4193], in skin fibroblast cultures after knockdown of TP53 [GeneID=7157] by RNAi."} {"geneset":"ITO_PTTG1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ITO_PTTG1_TARGETS_UP","description":"Genes up-regulated in HSA/c and KYSE140 cells (esophageal squamous cell carcinoma, ESCC) after knockdown of PTTG1 [GeneID=9232] by RNAi."} {"geneset":"ITO_PTTG1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ITO_PTTG1_TARGETS_DN","description":"Genes down-regulated in HSA/c and KYSE140 cells (esophageal squamous cell carcinoma, ESCC) after knockdown of PTTG1 [GeneID=9232] by RNAi."} {"geneset":"LE_SKI_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LE_SKI_TARGETS_UP","description":"Selected genes implicated in metastasis and epithelial-to-mesenchymal transition (EMT) which were up-regulated in MDA-MB-231 cells (breast cancer) upon knockdown of SKI [GeneID=6497] by RNAi."} {"geneset":"LE_SKI_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LE_SKI_TARGETS_DN","description":"Selected genes implicated in metastasis and epithelial-to-mesenchymal transition (EMT) which were down-regulated in MDA-MB-231 cells (breast cancer) upon knockdown of SKI [GeneID=6497] by RNAi."} {"geneset":"BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP","description":"Top highly correlated genes positively associated with poor survival of patients with suboptimally debulked ovarian tumors."} {"geneset":"BONOME_OVARIAN_CANCER_POOR_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BONOME_OVARIAN_CANCER_POOR_SURVIVAL_DN","description":"Top highly correlated genes negatively associated with poor survival of patients with suboptimally debulked ovarian tumors."} {"geneset":"BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING","description":"Genes whose expression in optimally debulked ovarian tumors is associated with survival prognosis."} {"geneset":"BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING","description":"Genes whose expression in suboptimally debulked ovarian tumors is associated with survival prognosis."} {"geneset":"GALI_TP53_TARGETS_APOPTOTIC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALI_TP53_TARGETS_APOPTOTIC_UP","description":"Apoptosis genes up-regulated by TP53 [GeneID=7157] in HCT116 cells (colon cancer) treated with thymoquinone [PubChem=10281]."} {"geneset":"GALI_TP53_TARGETS_APOPTOTIC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GALI_TP53_TARGETS_APOPTOTIC_DN","description":"Apoptosis genes down-regulated by TP53 [GeneID=7157] in HCT116 cells (colon cancer) treated with thymoquinone [PubChem=10281]."} {"geneset":"MOSERLE_IFNA_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOSERLE_IFNA_RESPONSE","description":"Top 50 genes up-regulated in ovarian cancer progenitor cells (also known as side population, SP, cells) in response to interferon alpha (IFNA)."} {"geneset":"MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER","description":"Genes silenced in HCT116 cells (colon cancer) by methylation of CpG islands in their promoters."} {"geneset":"WILSON_PROTEASES_AT_TUMOR_BONE_INTERFACE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILSON_PROTEASES_AT_TUMOR_BONE_INTERFACE_UP","description":"Protease genes up-regulated at tumor-bone interface compared to the tumor alone area."} {"geneset":"WILSON_PROTEASES_AT_TUMOR_BONE_INTERFACE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILSON_PROTEASES_AT_TUMOR_BONE_INTERFACE_DN","description":"Protease genes down-regulated at tumor-bone interface compared to the tumor alone area."} {"geneset":"WEBER_METHYLATED_HCP_IN_FIBROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_HCP_IN_FIBROBLAST_UP","description":"Methylated germline-specific genes with high-CpG-density promoters (HCP) in primary fibroblasts."} {"geneset":"WEBER_METHYLATED_HCP_IN_FIBROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_HCP_IN_FIBROBLAST_DN","description":"Unmethylated germline-specific genes with high-CpG-density promoters (HCP) in primary fibroblasts."} {"geneset":"WEBER_METHYLATED_HCP_IN_SPERM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_HCP_IN_SPERM_DN","description":"Unmethylated germline-specific genes with high-CpG-density promoters (HCP) in sperm."} {"geneset":"WEBER_METHYLATED_HCP_IN_SPERM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_HCP_IN_SPERM_UP","description":"Methylated germline-specific genes with high-CpG-density promoters (HCP) in sperm."} {"geneset":"BASSO_HAIRY_CELL_LEUKEMIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BASSO_HAIRY_CELL_LEUKEMIA_UP","description":"Genes up-regulated in hairy cell leukemia (HCL) compared with normal and other neoplastic B cell populations."} {"geneset":"BASSO_HAIRY_CELL_LEUKEMIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BASSO_HAIRY_CELL_LEUKEMIA_DN","description":"Genes down-regulated in hairy cell leukemia (HCL) compared with normal and other neoplastic B cell populations."} {"geneset":"TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C","description":"Genes down-regulated in HCT116 cells (colon cancer) upon expression of MIR34B or MIR34C [GeneID=407041;407042] microRNAs."} {"geneset":"IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP","description":"Genes up-regulated in adipose tissue mesenchymal stem cells (ASC) vs bone marrow mesenchymal stem cells (rBMSC)"} {"geneset":"IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN","description":"Genes down-regulated in adipose tissue mesenchymal stem cells (ASC) vs bone marrow mesenchymal stem cells (rBMSC)"} {"geneset":"ZHANG_BREAST_CANCER_PROGENITORS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_BREAST_CANCER_PROGENITORS_UP","description":"Genes up-regulated in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells."} {"geneset":"ZHANG_BREAST_CANCER_PROGENITORS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_BREAST_CANCER_PROGENITORS_DN","description":"Genes down-regulated in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells."} {"geneset":"MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN","description":"Top genes down-regulated in mesenchyme stem cells (MSC) grown in a tumor conditioned medium, which leads to carcinoma-associated fibroblast phenotype."} {"geneset":"BERNARD_PPAPDC1B_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERNARD_PPAPDC1B_TARGETS_UP","description":"Genes up-regulated in ZR-75-1 cells (breast cancer, amplified 8p11-12 region) upon knockdown of PPAPDC1B [GeneID=84513] by RNAi."} {"geneset":"BERNARD_PPAPDC1B_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERNARD_PPAPDC1B_TARGETS_DN","description":"Genes down-regulated in ZR-75-1 cells (breast cancer, amplified 8p11-12 region) upon knockdown of PPAPDC1B [GeneID=84513] by RNAi."} {"geneset":"GAURNIER_PSMD4_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAURNIER_PSMD4_TARGETS","description":"Inflammatory cytokines, chemokines and their cognate receptors up-regulated in THP-1 cells (monocyte) after treatment with PSMD4 [GeneID=5710]."} {"geneset":"EHLERS_ANEUPLOIDY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EHLERS_ANEUPLOIDY_UP","description":"Up-regulated genes in the expression signature of aneuploidy in uveal melanoma tumors: low vs high aneuploidy."} {"geneset":"EHLERS_ANEUPLOIDY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EHLERS_ANEUPLOIDY_DN","description":"Down-regulated genes in the expression signature of aneuploidy in uveal melanoma tumors: low vs high aneuploidy."} {"geneset":"ZHENG_GLIOBLASTOMA_PLASTICITY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_GLIOBLASTOMA_PLASTICITY_UP","description":"The glioblastoma multiforme (GBM) plasticity signature: genes up-regulated in neural stem cells (NSC) with double knockout of TP53 and PTEN [GeneID=7157;5728] vs those with knockout of TP53 alone."} {"geneset":"ZHENG_GLIOBLASTOMA_PLASTICITY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_GLIOBLASTOMA_PLASTICITY_DN","description":"The glioblastoma multiforme (GBM) plasticity signature: genes down-regulated in neural stem cells (NSC) with double knockout of TP53 and PTEN [GeneID=7157;5728] vs those with knockout of TP53 alone."} {"geneset":"BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_UP","description":"Genes up-regulated in microdissected endothelial samples from ovarian cancer tumors with tumor-infiltrating lymphocytes (TIL) vs those without TILs."} {"geneset":"BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_DN","description":"Genes down-regulated in microdissected endothelial samples from ovarian cancer tumors with tumor-infiltrating lymphocytes (TIL) vs those without TILs."} {"geneset":"JONES_TCOF1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JONES_TCOF1_TARGETS","description":"Genes up-regulated in E8.5 embryos with heterozygous knockout of TCOF1 [GeneID=6949] compared to wild type."} {"geneset":"AUJLA_IL22_AND_IL17A_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AUJLA_IL22_AND_IL17A_SIGNALING","description":"Genes changed in HBE cells (bronchial epithelium) after treatment with IL22 and IL17A [GeneID=50616;3605]."} {"geneset":"ZHENG_IL22_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_IL22_SIGNALING_UP","description":"Genes up-regulated in ex-vivo colonic tissue after treatment with IL22 [GeneID=50616]."} {"geneset":"ZHENG_IL22_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHENG_IL22_SIGNALING_DN","description":"Genes down-regulated in ex-vivo colonic tissue after treatment with IL22 [GeneID=50616]."} {"geneset":"BOCHKIS_FOXA2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOCHKIS_FOXA2_TARGETS","description":"Direct targets of FOXA2 [GeneID=3170] in liver, according to a ChIP-chip analysis."} {"geneset":"HONMA_DOCETAXEL_RESISTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HONMA_DOCETAXEL_RESISTANCE","description":"Genes up-regulated in MCF7-ADR cell line (breast cancer) resistant to docetaxel [PubChem=148124]."} {"geneset":"WILENSKY_RESPONSE_TO_DARAPLADIB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WILENSKY_RESPONSE_TO_DARAPLADIB","description":"Atherosclerotic process genes whose coronary expression changed after darapladib [PubChem=9939609] treatment."} {"geneset":"MATZUK_OVULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_OVULATION","description":"Genes important for ovulation, based on mouse models with female fertility defects."} {"geneset":"MATZUK_CUMULUS_EXPANSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_CUMULUS_EXPANSION","description":"Genes important for cumulus expansion, based on mouse models with female fertility defects."} {"geneset":"MATZUK_FERTILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_FERTILIZATION","description":"Genes important for fertilization, based on mouse models with female fertility defects."} {"geneset":"MATZUK_MATERNAL_EFFECT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_MATERNAL_EFFECT","description":"Maternal effect genes, based on mouse models wih female fertility defects."} {"geneset":"MATZUK_IMPLANTATION_AND_UTERINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_IMPLANTATION_AND_UTERINE","description":"Genes important for implantation and uterine, based on mouse models with female fertility defects."} {"geneset":"MATZUK_POSTIMPLANTATION_AND_POSTPARTUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_POSTIMPLANTATION_AND_POSTPARTUM","description":"Genes important for post-implantation and post-partum, based on mouse models with female fertility defects."} {"geneset":"MATZUK_STEROIDOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_STEROIDOGENESIS","description":"Genes important for steroidogenesis, based on mouse models with female fertility defects."} {"geneset":"MATZUK_MEIOTIC_AND_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_MEIOTIC_AND_DNA_REPAIR","description":"Meitic and DNA repair genes important for female fertility, based on mouse models with female fertility defects."} {"geneset":"MATZUK_CENTRAL_FOR_FEMALE_FERTILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_CENTRAL_FOR_FEMALE_FERTILITY","description":"Genes central for female fertility pathways, based on mouse models with female fertility defects."} {"geneset":"MATZUK_EMBRYONIC_GERM_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_EMBRYONIC_GERM_CELL","description":"Genes important for embryonic germ cell, based on mouse models with female fertility defects."} {"geneset":"MATZUK_EARLY_ANTRAL_FOLLICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_EARLY_ANTRAL_FOLLICLE","description":"Genes important for early anral follicle, based on mouse models with female fertility defects."} {"geneset":"MATZUK_LUTEAL_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_LUTEAL_GENES","description":"Luteal genes, based on mouse models with female fertility defects."} {"geneset":"MATZUK_PREOVULATORY_FOLLICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_PREOVULATORY_FOLLICLE","description":"Genes important for preovulatory follicle, based on mouse models with female fertility defects."} {"geneset":"MATZUK_MALE_REPRODUCTION_SERTOLI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_MALE_REPRODUCTION_SERTOLI","description":"Genes important for Sertoli, peritubular, Leydig and interstitial cells, based on mouse models with male reproductive defects."} {"geneset":"MATZUK_SPERMATOGONIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_SPERMATOGONIA","description":"Genes important for spermatogonia, based on mouse models with male reproductive defects."} {"geneset":"MATZUK_SPERMATOCYTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_SPERMATOCYTE","description":"Genes important for spermatocyte, based on mouse models with male reproductive defects."} {"geneset":"MATZUK_SPERMATID_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_SPERMATID_DIFFERENTIATION","description":"Genes important for spermatid differentiation, based on mouse models with male reproductive defects."} {"geneset":"MATZUK_SPERMATOZOA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATZUK_SPERMATOZOA","description":"Spermatozoa genes, based on mouse models with male reproductive defects."} {"geneset":"BONCI_TARGETS_OF_MIR15A_AND_MIR16_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BONCI_TARGETS_OF_MIR15A_AND_MIR16_1","description":"Potential targets of MIR15A and MIR16-1 [GeneID=406948;406950] microRNAs in prostate cancer."} {"geneset":"CHUNG_BLISTER_CYTOTOXICITY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHUNG_BLISTER_CYTOTOXICITY_UP","description":"Genes up-regulated in blister cells from patients with adverse drug reactions (ADR)."} {"geneset":"CHUNG_BLISTER_CYTOTOXICITY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHUNG_BLISTER_CYTOTOXICITY_DN","description":"Genes down-regulated in blister cells from patients with adverse drug reactions (ADR)."} {"geneset":"WHITEFORD_PEDIATRIC_CANCER_MARKERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITEFORD_PEDIATRIC_CANCER_MARKERS","description":"Differentially expressed genes in a panel of xenografts representing 8 common pediatric tumors compared to the normal tissues."} {"geneset":"GRADE_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRADE_METASTASIS_DN","description":"Down-regulated genes in colon carcinoma tumors with lymph node metastases."} {"geneset":"GRADE_COLON_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRADE_COLON_CANCER_UP","description":"Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples."} {"geneset":"GRADE_COLON_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRADE_COLON_CANCER_DN","description":"Down-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples."} {"geneset":"GRADE_COLON_AND_RECTAL_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRADE_COLON_AND_RECTAL_CANCER_UP","description":"Up-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples."} {"geneset":"GRADE_COLON_AND_RECTAL_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRADE_COLON_AND_RECTAL_CANCER_DN","description":"Down-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples."} {"geneset":"GRADE_COLON_VS_RECTAL_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRADE_COLON_VS_RECTAL_CANCER_UP","description":"Genes up-regulated in rectal but down-regulated in colon carcinoma compared to normal mucosa samples."} {"geneset":"GRADE_COLON_VS_RECTAL_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRADE_COLON_VS_RECTAL_CANCER_DN","description":"Genes down-regulated in rectal but up-regulated in colon carcinoma compared to normal mucosa samples."} {"geneset":"BOQUEST_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOQUEST_STEM_CELL_UP","description":"Genes up-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts."} {"geneset":"BOQUEST_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOQUEST_STEM_CELL_DN","description":"Genes down-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts."} {"geneset":"BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP","description":"Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells."} {"geneset":"BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN","description":"Genes down-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells."} {"geneset":"LABBE_WNT3A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LABBE_WNT3A_TARGETS_UP","description":"Up-regulated genes in NMuMG cells (mammary epithelium) after stimulation with WNT3A [GeneID=89780]."} {"geneset":"LABBE_WNT3A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LABBE_WNT3A_TARGETS_DN","description":"Down-regulated genes in NMuMG cells (mammary epithelium) after stimulation with WNT3A [GeneID=89780]."} {"geneset":"LABBE_TGFB1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LABBE_TGFB1_TARGETS_UP","description":"Up-regulated genes in NMuMG cells (mammary epithelium) after stimulation with TGFB1 [GeneID=7040]."} {"geneset":"LABBE_TGFB1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LABBE_TGFB1_TARGETS_DN","description":"Down-regulated genes in NMuMG cells (mammary epithelium) after stimulation with TGFB1 [GeneID=7040]."} {"geneset":"LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP","description":"Up-regulated genes in NMuMG cells (mammary epithelium) after stimulation with both TGFB1 and WNT3A [GeneID=7040;89780]."} {"geneset":"LABBE_TARGETS_OF_TGFB1_AND_WNT3A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LABBE_TARGETS_OF_TGFB1_AND_WNT3A_DN","description":"Down-regulated genes in NMuMG cells (mammary epithelium) after stimulation with both TGFB1 and WNT3A [GeneID=7040;89780]."} {"geneset":"NAKAMURA_METASTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_METASTASIS","description":"Genes up-regulated in highly metastatic pancreatic cancer cells."} {"geneset":"NAKAMURA_METASTASIS_MODEL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_METASTASIS_MODEL_UP","description":"Top genes up-regulated in orthotopic tumors from highly metastatic pancreatic cancer cells."} {"geneset":"NAKAMURA_METASTASIS_MODEL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_METASTASIS_MODEL_DN","description":"Bottom genes down-regulated in subcutaneous tumors from highly metastatic pancreatic cancer cells."} {"geneset":"GRATIAS_RETINOBLASTOMA_16Q24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRATIAS_RETINOBLASTOMA_16Q24","description":"Genes from 16q24 region up-regulated in retinoblastoma tumors with 16q24 LOH (loss of heterozygocity) compared to those without the LOH."} {"geneset":"WEST_ADRENOCORTICAL_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEST_ADRENOCORTICAL_TUMOR_UP","description":"Up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue."} {"geneset":"WEST_ADRENOCORTICAL_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEST_ADRENOCORTICAL_TUMOR_DN","description":"Down-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue."} {"geneset":"WEST_ADRENOCORTICAL_CARCINOMA_VS_ADENOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEST_ADRENOCORTICAL_CARCINOMA_VS_ADENOMA_UP","description":"Up-regulated genes in pediatric adrenocortical carcinoma (ACC) compared to the adenoma (ACA) tumors."} {"geneset":"WEST_ADRENOCORTICAL_CARCINOMA_VS_ADENOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEST_ADRENOCORTICAL_CARCINOMA_VS_ADENOMA_DN","description":"Down-regulated genes in pediatric adrenocortical carcinoma (ACC) compared to the adenoma (ACA) tumors."} {"geneset":"DONATO_CELL_CYCLE_TRETINOIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DONATO_CELL_CYCLE_TRETINOIN","description":"Genes involved in cell cycle regulation which were up-regulated in MCF-7 cells (breast cancer) by tretinoin (retinoic acid) [PubChem=444795]."} {"geneset":"CHO_NR4A1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHO_NR4A1_TARGETS","description":"Genes up-regulated in RKO cells (colon cancer) after treatment with the NR4A1 [GeneID=3164] agonist, DIM-C-pPhOCH3."} {"geneset":"BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP","description":"Up-regulated genes in MDA-MB-435 cells (breast cancer) undergoing G2/M arrest after treatment with 2-methoxyestradiol (2ME2)[PubChem=1573]."} {"geneset":"BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN","description":"Down-regulated genes in MDA-MB-435 cells (breast cancer) undergoing G2/M arrest after treatment with 2-methoxyestradiol (2ME2) [PubChem=1573]."} {"geneset":"CLIMENT_BREAST_CANCER_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CLIMENT_BREAST_CANCER_COPY_NUMBER_UP","description":"Genes from the most frequent genomic gains and amplifications in a panel of patients with lymph node negative breast cancer (NNBC)."} {"geneset":"CLIMENT_BREAST_CANCER_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CLIMENT_BREAST_CANCER_COPY_NUMBER_DN","description":"Genes from the most frequent genomic losses and homozygous deletions in a panel of patients with lymph node negative breast cancer (NNBC)."} {"geneset":"SHARMA_ASTROCYTOMA_WITH_NF1_SYNDROM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHARMA_ASTROCYTOMA_WITH_NF1_SYNDROM","description":"Genes up-regulated in pilocytic astrocytoma (PA) samples from patients with type 1 neurofibromatosis syndrom (NF1) compared to the PA tumors from non-NF1 patients."} {"geneset":"SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP","description":"Genes up-regulated in pilocytic astrocytoma (PA) from supratentorial regions compared to the infratentorial PA tumors."} {"geneset":"SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_DN","description":"Genes down-regulated in pilocytic astrocytoma (PA) from supratentorial regions compared to the infratentorial PA tumors."} {"geneset":"TSUDA_ALVEOLAR_SOFT_PART_SARCOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSUDA_ALVEOLAR_SOFT_PART_SARCOMA","description":"Protein kinase genes most significantly up-regulated in ASPS (alveolar soft part sarcoma) tumors compared to four other types of primitive sarcomas."} {"geneset":"RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP","description":"Up-regulated genes in breast tumors from transgenic mice overexpressing ERBB2 and CDC25A [GeneID=2064;993] compared to those from mice overexpressing ERBB2 only."} {"geneset":"RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN","description":"Down-regulated genes in breast tumors from transgenic mice overexpressing ERBB2 and CDC25A [GeneID=2064;993] compared to those from mice overexpressing ERBB2 only."} {"geneset":"YAGUE_PRETUMOR_DRUG_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGUE_PRETUMOR_DRUG_RESISTANCE_UP","description":"Up-regulated genes common to all pretumorigenic cells with acquired drug resistance."} {"geneset":"YAGUE_PRETUMOR_DRUG_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGUE_PRETUMOR_DRUG_RESISTANCE_DN","description":"Down-regulated genes common to all pretumorigenic cells with acquired drug resistance."} {"geneset":"BRUECKNER_TARGETS_OF_MIRLET7A3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUECKNER_TARGETS_OF_MIRLET7A3_UP","description":"Genes up-regulated in A549 cells (lung cancer) expressing MIRLET7A3 [GeneID=406883] microRNA off a plasmid vector."} {"geneset":"BRUECKNER_TARGETS_OF_MIRLET7A3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUECKNER_TARGETS_OF_MIRLET7A3_DN","description":"Genes down-regulated in A549 cells (lung cancer) expressing MIRLET7A3 [GeneID=406883] microRNA off a plasmid vector."} {"geneset":"PODAR_RESPONSE_TO_ADAPHOSTIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PODAR_RESPONSE_TO_ADAPHOSTIN_UP","description":"Up-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042], a tyrosine kinase inhibitor with anticancer properties."} {"geneset":"PODAR_RESPONSE_TO_ADAPHOSTIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PODAR_RESPONSE_TO_ADAPHOSTIN_DN","description":"Down-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042], a tyrosine kinase inhibitor with anticancer properties."} {"geneset":"LU_TUMOR_ENDOTHELIAL_MARKERS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_TUMOR_ENDOTHELIAL_MARKERS_UP","description":"Genes specifically up-regulated in tumor endothelium."} {"geneset":"LU_TUMOR_ENDOTHELIAL_MARKERS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_TUMOR_ENDOTHELIAL_MARKERS_DN","description":"Genes specifically down-regulated in tumor endothelium."} {"geneset":"LU_TUMOR_ANGIOGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_TUMOR_ANGIOGENESIS_UP","description":"Up-regulated genes of putative pathways stimulated in tumor endothelial cells by papillary serous ovarian epithelial tumor cells."} {"geneset":"LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK","description":"Genes up-regulated in highly immune-resistant cancer cell line developed from a susceptible cancer using an in vivo selection strategy."} {"geneset":"CHEN_HOXA5_TARGETS_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_HOXA5_TARGETS_6HR_UP","description":"Genes up-regulated 6 h after induction of HoxA5 [GeneID=3205] expression in a breast cancer cell line."} {"geneset":"CHEN_HOXA5_TARGETS_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_HOXA5_TARGETS_6HR_DN","description":"Genes down-regulated 6 h after induction of HoxA5 [GeneID=3205] expression in a breast cancer cell line."} {"geneset":"CHEN_HOXA5_TARGETS_9HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_HOXA5_TARGETS_9HR_UP","description":"Genes up-regulated 9 h after induction of HoxA5 [GeneID=3205] expression in a breast cancer cell line."} {"geneset":"CHEN_HOXA5_TARGETS_9HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_HOXA5_TARGETS_9HR_DN","description":"Genes down-regulated 9 h after induction of HoxA5 [GeneID=3205] expression in a breast cancer cell line."} {"geneset":"LIN_NPAS4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIN_NPAS4_TARGETS_UP","description":"Genes up-regulated in neurons after NPAS4 [GeneID=266743] knockdown by RNAi."} {"geneset":"LIN_NPAS4_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIN_NPAS4_TARGETS_DN","description":"Genes down-regulated in neurons after NPAS4 [GeneID=266743] knockdown by RNAi."} {"geneset":"CADWELL_ATG16L1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CADWELL_ATG16L1_TARGETS_UP","description":"Genes up-regulated in Paneth cell (part of intestiinal epithelium) of mice with hypomorphic (reduced function) form of ATG16L1 [GeneID=55054]."} {"geneset":"CADWELL_ATG16L1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CADWELL_ATG16L1_TARGETS_DN","description":"Genes down-regulated in Paneth cell (part of intestiinal epithelium) of mice with hypomorphic (reduced function) form of ATG16L1 [GeneID=55054]."} {"geneset":"BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP","description":"Genes up-regulated in pre B lymphocyte after induction of physiological DNA double-strand breaks (DSB) by RAG2 [GeneID=5897]; the changes are independent of ATM [GeneID=472] signaling."} {"geneset":"BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN","description":"Genes down-regulated in pre B lymphocyte after induction of physiological DNA double-strand breaks (DSB) by RAG2 [GeneID=5897]; the changes are independent of ATM [GeneID=472] signaling."} {"geneset":"BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP","description":"Genes up-regulated in pre B lymphocyte after induction of physiological DNA double-strand breaks (DSB) by RAG2 [GeneID=5897]; the changes depend on ATM [GeneID=472] but not NFKB signaling."} {"geneset":"BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN","description":"Genes down-regulated in pre B lymphocyte after induction of physiological DNA double-strand breaks (DSB) by RAG2 [GeneID=5897]; the changes depend on ATM [GeneID=472] but not NFKB signaling."} {"geneset":"CONRAD_STEM_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CONRAD_STEM_CELL","description":"Supplementary Table 2. Genelist comparing microarray expression profiles of spermatogonial cells, haGSCs and hES (H1) cells. Examples of expression rates of different hES cell enriched and germ cell specific genes, surface markers for germ cell selection and signal transduction in all three cell types (spermatogonial cells = SC)."} {"geneset":"CONRAD_GERMLINE_STEM_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CONRAD_GERMLINE_STEM_CELL","description":"Genes enriched in pluripotent adult germline stem cells."} {"geneset":"THUM_MIR21_TARGETS_HEART_DISEASE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THUM_MIR21_TARGETS_HEART_DISEASE_UP","description":"Genes up-regulated in a mouse model of heart disease whose expression reverted to normal by silencing of MIR21 [GeneID=406991] microRNA."} {"geneset":"THUM_MIR21_TARGETS_HEART_DISEASE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THUM_MIR21_TARGETS_HEART_DISEASE_DN","description":"Genes down-regulated in a mouse model of heart disease whose expression reverted to normal by silencing of MIR21 [GeneID=406991] microRNA."} {"geneset":"KUUSELO_PANCREATIC_CANCER_19Q13_AMPLIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUUSELO_PANCREATIC_CANCER_19Q13_AMPLIFICATION","description":"List of genes in the 19q13 amplicon region based on a copy number alterations study of a panel of 16 pancreatic cancer cell lines and 31 primary tumors."} {"geneset":"HUANG_DASATINIB_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUANG_DASATINIB_RESISTANCE_UP","description":"Genes whose expression positively correlated with sensitivity of breast cancer cell lines to dasatinib [PubChem=3062316]."} {"geneset":"HUANG_DASATINIB_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUANG_DASATINIB_RESISTANCE_DN","description":"Genes whose expression negatively correlated with resistance of breast cancer cell lines to dasatinib [PubChem=3062316]."} {"geneset":"MATTHEWS_SKIN_CARCINOGENESIS_VIA_JUN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATTHEWS_SKIN_CARCINOGENESIS_VIA_JUN","description":"Genes up-regulated by skin tumor promoters but completely blocked by expression of TAM67, a dominan-negative form of JUN [GeneID=3725]."} {"geneset":"MATTHEWS_AP1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MATTHEWS_AP1_TARGETS","description":"Known targets of AP1 that were down-regulated by overexpression of TAM67, a dominant-negative form of JUN [GeneID=3725]."} {"geneset":"QI_PLASMACYTOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/QI_PLASMACYTOMA_UP","description":"Up-regulated genes that best disciminate plasmablastic plasmacytoma from plasmacytic plasmacytoma tumors."} {"geneset":"QI_PLASMACYTOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/QI_PLASMACYTOMA_DN","description":"Down-regulated genes that best disciminate plasmablastic plasmacytoma from plasmacytic plasmacytoma tumors."} {"geneset":"TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA","description":"Genes whose DNA methylation differed between primary ALL cells (acute lymphoblastic leukemia) and normal peripheral blood samples."} {"geneset":"CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP","description":"Protein biosynthesis, transport or catabolism genes up-regulated in hyperploid multiple myeloma (MM) compared to the non-hyperploid MM samples."} {"geneset":"CHNG_MULTIPLE_MYELOMA_HYPERPLOID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHNG_MULTIPLE_MYELOMA_HYPERPLOID_DN","description":"Protein biosynthesis, transport or catabolism genes down-regulated in hyperploid multiple myeloma (MM) compared to the non-hyperploid MM samples."} {"geneset":"HUPER_BREAST_BASAL_VS_LUMINAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUPER_BREAST_BASAL_VS_LUMINAL_UP","description":"Genes up-regulated in basal mammary epithelial cells compared to the luminal ones."} {"geneset":"HUPER_BREAST_BASAL_VS_LUMINAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUPER_BREAST_BASAL_VS_LUMINAL_DN","description":"Genes down-regulated in basal mammary epithelial cells compared to the luminal ones."} {"geneset":"MALONEY_RESPONSE_TO_17AAG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MALONEY_RESPONSE_TO_17AAG_UP","description":"Up-regulated genes in A2780 cells (ovarian cancer) treated with 17AAG [PubChem=6440175], a chemical with anticancer properties."} {"geneset":"MALONEY_RESPONSE_TO_17AAG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MALONEY_RESPONSE_TO_17AAG_DN","description":"Down-regulated genes in A2780 cells (ovarian cancer) treated with 17AAG [PubChem=6440175], a chemical with anticancer properties."} {"geneset":"CUI_GLUCOSE_DEPRIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CUI_GLUCOSE_DEPRIVATION","description":"Representative genes up-regulated in MiaPaCa2 cells (pancreatic cancer) under glucose-deprived conditions."} {"geneset":"BLUM_RESPONSE_TO_SALIRASIB_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BLUM_RESPONSE_TO_SALIRASIB_UP","description":"Selected genes up-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [GeneID=3265]."} {"geneset":"BLUM_RESPONSE_TO_SALIRASIB_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BLUM_RESPONSE_TO_SALIRASIB_DN","description":"Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [GeneID=3265]."} {"geneset":"WINTER_HYPOXIA_METAGENE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WINTER_HYPOXIA_METAGENE","description":"Genes regulated by hypoxia, based on literature searches."} {"geneset":"ALONSO_METASTASIS_EMT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALONSO_METASTASIS_EMT_UP","description":"EMT (epithelial-mesenchymal transition) genes up-regulated genes in melanoma tumous that developed metastatic disease compared to primary melanoma that did not."} {"geneset":"ALONSO_METASTASIS_EMT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALONSO_METASTASIS_EMT_DN","description":"EMT (epithelial-mesenchymal transition) genes down-regulated genes in melanoma tumous that developed metastatic disease compared to primary melanoma that did not."} {"geneset":"ALONSO_METASTASIS_NEURAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALONSO_METASTASIS_NEURAL_UP","description":"Neural-related genes up-regulated in melanoma tumors that developed metastases compared to primary melanoma that did not."} {"geneset":"ALONSO_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALONSO_METASTASIS_UP","description":"Up-regulated genes in melanoma tumous that developed metastatic disease compared to primary melanoma that did not."} {"geneset":"ALONSO_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALONSO_METASTASIS_DN","description":"Down-regulated genes in melanoma tumors that developed metastatic disease compared to primary melanoma that did not."} {"geneset":"CROMER_TUMORIGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROMER_TUMORIGENESIS_UP","description":"Tumorigenesis markers of head and neck squamous cell carcinoma (HNSCC): up-regulated in the 'early' tumors vs normal samples."} {"geneset":"CROMER_TUMORIGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROMER_TUMORIGENESIS_DN","description":"Tumorigenesis markers of head and neck squamous cell carcinoma (HNSCC): down-regulated in the 'early' tumors vs normal samples."} {"geneset":"KRISHNAN_FURIN_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRISHNAN_FURIN_TARGETS_UP","description":"Genes up-regulated in naive T lymphocytes lacking FURIN [GeneID=5045]: Cre-Lox knockout of FURIN in CD4+ [GeneID=920] cells."} {"geneset":"KRISHNAN_FURIN_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRISHNAN_FURIN_TARGETS_DN","description":"Genes down-regulated in naive T lymphocytes lacking FURIN [GeneID=5045]: Cre-Lox knockout of FURIN in CD4+ [GeneID=920] cells."} {"geneset":"MUELLER_PLURINET","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MUELLER_PLURINET","description":"Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells, embryonical carcinomas and induced pluripotent cells)."} {"geneset":"YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP","description":"Genes up-regulated in mouse stroma of pancreatic adenocarcinoma zenografts after treatment with HhAntag, a hedgehog (Hh) pathway inhibitor."} {"geneset":"YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN","description":"Genes down-regulated in mouse stroma of pancreatic adenocarcinoma zenografts after treatment with HhAntag, a hedgehog (Hh) pathway inhibitor."} {"geneset":"FIRESTEIN_CTNNB1_PATHWAY_AND_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIRESTEIN_CTNNB1_PATHWAY_AND_PROLIFERATION","description":"Genes required for both proliferation and CTNNB1 [GeneID=1499] activity in DLD-1 cell (colon cancer with APC [GeneID=324] deletions)."} {"geneset":"FIRESTEIN_CTNNB1_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIRESTEIN_CTNNB1_PATHWAY","description":"Genes required for CTNNB1 [GeneID=1499] activity in DLD-1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen."} {"geneset":"FIRESTEIN_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIRESTEIN_PROLIFERATION","description":"Genes required for proliferation of DLD-1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen."} {"geneset":"ZHOU_PANCREATIC_EXOCRINE_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_PANCREATIC_EXOCRINE_PROGENITOR","description":"Transcription factors expressed in progenitors of exocrine pancreatic cells."} {"geneset":"ZHOU_PANCREATIC_ENDOCRINE_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_PANCREATIC_ENDOCRINE_PROGENITOR","description":"Transcription factors expressed in progenitors of endocrine pancreatic cells."} {"geneset":"ZHOU_PANCREATIC_BETA_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_PANCREATIC_BETA_CELL","description":"Transcription factors expressed in adult pancreatic beta cells."} {"geneset":"ISHIKAWA_STING_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ISHIKAWA_STING_SIGNALING","description":"Prmary innate immune response genes induced in 293T cells (embryonic kidney) by overexpression of STING (TMEM173) [GeneID=340061]."} {"geneset":"WANG_TUMOR_INVASIVENESS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_TUMOR_INVASIVENESS_UP","description":"Up-regulated genes in the subpopulation of invasive PyMT cells (breast cancer) compared to the general population of PyMT cells."} {"geneset":"WANG_TUMOR_INVASIVENESS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_TUMOR_INVASIVENESS_DN","description":"Down-regulated genes in the subpopulation of invasive PyMT cells (breast cancer) compared to the general population of PyMT cells."} {"geneset":"JIANG_TIP30_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_TIP30_TARGETS_UP","description":"Up-regulated genes in HepG2 cells (liver cancer) overexpressing an oncogenic variant of tumor suppressor TIP30 [GeneID=10553] compared to its wild type form."} {"geneset":"JIANG_TIP30_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_TIP30_TARGETS_DN","description":"Down-regulated genes in HepG2 cells (liver cancer) overexpressing an oncogenic variant of tumor suppressor TIP30 [GeneID=10553] compared to its wild type form."} {"geneset":"GRESHOCK_CANCER_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRESHOCK_CANCER_COPY_NUMBER_UP","description":"Genes from common genomic gains observed in a meta analyis of copy number alterations across a panel of different cancer cell lines and tumor samples."} {"geneset":"WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC","description":"Selected genes changed in NMuMG cells (mammary epithelium) transformed by overexpression of CCND1 [GeneID=595] vs those transformed by overexpression of CCND1 and MYC [GeneID=4609]."} {"geneset":"TSAI_RESPONSE_TO_RADIATION_THERAPY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSAI_RESPONSE_TO_RADIATION_THERAPY","description":"Genes up-regulated in response to both single dose and fractionated radiation that were common to all three cell lines studied."} {"geneset":"SASAI_TARGETS_OF_CXCR6_AND_PTCH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASAI_TARGETS_OF_CXCR6_AND_PTCH1_UP","description":"Up-regulated genes in medulloblastoma tumors from heterozygotic CXCR6 [GeneID=10663] knockout mice compared to those from PTCH1 [GeneID=5727] heterozygotic knockout mice."} {"geneset":"SASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN","description":"Down-regulated genes in medulloblastoma tumors from heterozygotic CXCR6 [GeneID=10663] knockout mice compared to those from PTCH1 [GeneID=5727] heterozygotic knockout mice."} {"geneset":"MIKI_COEXPRESSED_WITH_CYP19A1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKI_COEXPRESSED_WITH_CYP19A1","description":"Nuclear receptors whose expression correlated with that of aromatase (CYP19A1) [GeneID=1588] in a panel of breast cancer biopsies."} {"geneset":"BEIER_GLIOMA_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BEIER_GLIOMA_STEM_CELL_UP","description":"Genes up-regulated in cancer stem cells derived from glyoblastoma tumors: CD133+ [GeneID=8842] vs. CD133- cells."} {"geneset":"BEIER_GLIOMA_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BEIER_GLIOMA_STEM_CELL_DN","description":"Genes down-regulated in cancer stem cells derived from glyoblastoma tumors: CD133+ [GeneID=8842] vs. CD133- cells."} {"geneset":"VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP","description":"Angiogenic markers up-regulated in lymph endothelial cells upon infection with KSHV (Kaposi's sarcoma herpes virus)."} {"geneset":"VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN","description":"Angiogenic markers down-regulated in lymph endothelial cells upon infection with KSHV (Kaposi's sarcoma herpes virus)."} {"geneset":"MOOTHA_HUMAN_MITODB_6_2002","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_HUMAN_MITODB_6_2002","description":"Mitochondrial genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets."} {"geneset":"MOOTHA_PGC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_PGC","description":"Genes up-regulated in differentiating C2C12 cells (myoblasts) upon expression of PPARGC1A [GeneID=10891] off an adenoviral vector."} {"geneset":"MOOTHA_TCA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_TCA","description":"Tricarboxylic acid related genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets."} {"geneset":"LEE_LIVER_CANCER_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_SURVIVAL_DN","description":"Genes highly expressed in hepatocellular carcinoma with poor survival."} {"geneset":"LEE_LIVER_CANCER_SURVIVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_SURVIVAL_UP","description":"Genes highly expressed in hepatocellular carcinoma with good survival."} {"geneset":"MOOTHA_MITOCHONDRIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_MITOCHONDRIA","description":"Mitochondrial genes"} {"geneset":"MOOTHA_ROS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_ROS","description":"Reactive oxidative species (ROS) genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets."} {"geneset":"DAVIES_MULTIPLE_MYELOMA_VS_MGUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVIES_MULTIPLE_MYELOMA_VS_MGUS_UP","description":"Genes up-regulated in multiple myeloma (MM) compared to monoclonal gammopathy of uncertain significance (MGUS)."} {"geneset":"DAVIES_MULTIPLE_MYELOMA_VS_MGUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAVIES_MULTIPLE_MYELOMA_VS_MGUS_DN","description":"Genes down-regulated in multiple myeloma (MM) compared to monoclonal gammopathy of uncertain significance (MGUS)."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_UP","description":"Genes from cluster 1: up-regulated in group C of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN","description":"Genes from cluster 2: down-regulated in group C of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_UP","description":"Genes from cluster 3: up-regulated in group D of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN","description":"Genes from cluster 4: down-regulated in group D of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_D_UP","description":"Genes up-regulated in group D of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_D_DN","description":"Genes down-regulated in group D of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_C_D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_C_D_UP","description":"Genes up-regulated both in group C and D of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_C_D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_C_D_DN","description":"Genes down-regulated both in group C and D of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_C_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_C_UP","description":"Genes up-regulated in group C of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_C_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_C_DN","description":"Genes down-regulated in group C of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells."} {"geneset":"WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER","description":"Genes silenced by DNA methylation in bladder cancer cell lines."} {"geneset":"FERRARI_RESPONSE_TO_FENRETINIDE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERRARI_RESPONSE_TO_FENRETINIDE_UP","description":"Genes up-regulated in HUVEC cells (umbilical vein endothelium) by fenretinide [PubChem=1744]."} {"geneset":"FERRARI_RESPONSE_TO_FENRETINIDE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERRARI_RESPONSE_TO_FENRETINIDE_DN","description":"Genes down-regulated in HUVEC cells (umbilical vein endothelium) by fenretinide [PubChem=1744]."} {"geneset":"HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS","description":"Genes down-regulated in tumor-conditioned vs quiescent endothelial cells and up-regulated upon treatment with decitabine and TSA [PubChem=451668;5562]."} {"geneset":"REICHERT_G1S_REGULATORS_AS_PI3K_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REICHERT_G1S_REGULATORS_AS_PI3K_TARGETS","description":"G1 to S phase regulators significantly changed in DanG cells (pancreatic cancer) treated with Ly294002 [PubChem=3973], a phosphoinositide 3-kinase (PI3K) inhibitor."} {"geneset":"GU_PDEF_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GU_PDEF_TARGETS_UP","description":"Integrin, VEGF, Wnt and TGFbeta signaling pathway genes up-regulated in PC-3 cells (prostate cancer) after knockdown of PDEF [GeneID=25803] by RNAi."} {"geneset":"GU_PDEF_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GU_PDEF_TARGETS_DN","description":"Integrin, VEGF, Wnt and TGFbeta signaling pathway genes down-regulated in PC-3 cells (prostate cancer) after knockdown of PDEF [GeneID=25803] by RNAi."} {"geneset":"TOOKER_GEMCITABINE_RESISTANCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOOKER_GEMCITABINE_RESISTANCE_UP","description":"Up-regulated genes in Calu3 cells (non-small cell lung cancer, NSCLC) resistant to gemcitabine [PubChem=3461] which became down-regulated in response to bexarotene [PubChem=82146]."} {"geneset":"TOOKER_GEMCITABINE_RESISTANCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TOOKER_GEMCITABINE_RESISTANCE_DN","description":"Down-regulated genes in Calu3 cells (non-small cell lung cancer, NSCLC) resistant to gemcitabine [PubChem=3461] which became up-regulated in response to bexarotene [PubChem=82146]."} {"geneset":"BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP","description":"Genes up-regulated in B lymphocytes from patients with primary immunodefiency syndrom."} {"geneset":"BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_DN","description":"Genes down-regulated in B lymphocytes from patients with primary immunodefiency syndrom."} {"geneset":"FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_UP","description":"Up-regulated genes significantly associated with positive minimal residual disease (MRD) on day 46 after chemotherapy treatment of children with acute lymphoblastic leukemia (ALL)."} {"geneset":"FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_DN","description":"Down-regulated genes significantly associated with positive minimal residual disease (MRD) on day 46 after chemotherapy treatment of children with acute lymphoblastic leukemia (ALL)."} {"geneset":"VILIMAS_NOTCH1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VILIMAS_NOTCH1_TARGETS_UP","description":"Genes up-regulated in bone marrow progenitors by constitutively active NOTCH1 [GeneID=4851]."} {"geneset":"VILIMAS_NOTCH1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VILIMAS_NOTCH1_TARGETS_DN","description":"Genes down-regulated in bone marrow progenitors by constitutively active NOTCH1 [GeneID=4851]."} {"geneset":"SPIRA_SMOKERS_LUNG_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SPIRA_SMOKERS_LUNG_CANCER_UP","description":"Up-regulated genes that distinguished smokers with and without lung cancer."} {"geneset":"SPIRA_SMOKERS_LUNG_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SPIRA_SMOKERS_LUNG_CANCER_DN","description":"Down-regulated genes that distinguished smokers with and without lung cancer."} {"geneset":"LUDWICZEK_TREATING_IRON_OVERLOAD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LUDWICZEK_TREATING_IRON_OVERLOAD","description":"Genes changed in liver in response to nifedipine [PubChem=4485] treatment of iron overload."} {"geneset":"JU_AGING_TERC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JU_AGING_TERC_TARGETS_UP","description":"Cytokines, growth factors, and secreted proteins that show increased expression on a protein array of samples from aged TERC [GeneID=7012] knockout mice."} {"geneset":"JU_AGING_TERC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JU_AGING_TERC_TARGETS_DN","description":"Cytokines, growth factors, and secreted proteins that show decreased expression on a protein array of samples from aged TERC [GeneID=7012] knockout mice."} {"geneset":"ZAIDI_OSTEOBLAST_TRANSCRIPTION_FACTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZAIDI_OSTEOBLAST_TRANSCRIPTION_FACTORS","description":"An assortment of osteoblast transcriptional regulators."} {"geneset":"WAGNER_APO2_SENSITIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAGNER_APO2_SENSITIVITY","description":"Genes whose expression most significantly correlated with cancer cell line sensitivity to the proapoptotic ligand APO2 [GeneID=8797]."} {"geneset":"PALOMERO_GSI_SENSITIVITY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PALOMERO_GSI_SENSITIVITY_UP","description":"Up-regulated genes associated with sensitivity and resistance to gamma-secretase (GSI) in T-cell acute lymphoblastic leukemia (T-ALL) cell lines."} {"geneset":"PALOMERO_GSI_SENSITIVITY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PALOMERO_GSI_SENSITIVITY_DN","description":"Down-regulated genes associated with sensitivity and resistance to gamma-secretase (GSI) in T-cell acute lymphoblastic leukemia (T-ALL) cell lines."} {"geneset":"SOUCEK_MYC_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SOUCEK_MYC_TARGETS","description":"Chemokine genes up-regulated within 2 hr of c-Myc [GeneID=4609] activation in a mouse model of Myc-induced pancreatic beta-cell tumorigenesis."} {"geneset":"SEKI_INFLAMMATORY_RESPONSE_LPS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEKI_INFLAMMATORY_RESPONSE_LPS_UP","description":"Genes up-regulated in hepatic stellar cells after stimulation with bacterial lipopolysacharide (LPS)."} {"geneset":"SEKI_INFLAMMATORY_RESPONSE_LPS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEKI_INFLAMMATORY_RESPONSE_LPS_DN","description":"Genes down-regulated in hepatic stellar cells after stimulation with bacterial lipopolysacharide (LPS)."} {"geneset":"RAY_ALZHEIMERS_DISEASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAY_ALZHEIMERS_DISEASE","description":"A biomarker of plasma signaling proteins that predicts clinical Alzheimer's diagnosis."} {"geneset":"HUNSBERGER_EXERCISE_REGULATED_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUNSBERGER_EXERCISE_REGULATED_GENES","description":"Exercise regulated genes in hyppocampus."} {"geneset":"PIONTEK_PKD1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PIONTEK_PKD1_TARGETS_UP","description":"Genes up-regulated during later stages of renal maturation (days P14-P16) in kidney specific knockout of PKD1 [GeneID=5310]."} {"geneset":"PIONTEK_PKD1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PIONTEK_PKD1_TARGETS_DN","description":"Genes down-regulated during later stages of renal maturation (days P14-P16) in kidney specific knockout of PKD1 [GeneID=5310]."} {"geneset":"CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP","description":"Genes up-regulated by 2-methoxyestradiol (2ME2) [PubChem=1573] in the MM.1S cell line (multiple myeloma) sensitive to dexamethasone [PubChem=5743]."} {"geneset":"CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN","description":"Genes down-regulated by 2-methoxyestradiol (2ME2) [PubChem=1573] in the MM.1S cell line (multiple myeloma) sensitive to dexamethasone [PubChem=5743]."} {"geneset":"FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen, raloxifene, or ICI 182780 but not by estradiol [PubChem=44959;5035;3478439;5757]."} {"geneset":"FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen, raloxifene, or ICI 182780 but not by estradiol [PubChem=44959;5035;3478439;5757]."} {"geneset":"GOLDRATH_ANTIGEN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_ANTIGEN_RESPONSE","description":"Genes up-regulated at the peak of an antigen response of naive CD8+ [GeneID=925;926] T-cells."} {"geneset":"ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP","description":"Hepatic graft versus host disease (GVHD), day 7: up-regulated in allogeneic vs syngeneic bone marrow transplant."} {"geneset":"ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_DN","description":"Hepatic graft versus host disease (GVHD), day 7: down-regulated in allogeneic vs syngeneic bone marrow transplant."} {"geneset":"ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP","description":"Hepatic graft versus host disease (GVHD), day 35: genes up-regulated in allogeneic vs syngeneic bone marrow transplant."} {"geneset":"ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_DN","description":"Hepatic graft versus host disease (GVHD), day 35: genes down-regulated in allogeneic vs syngeneic bone marrow transplant."} {"geneset":"LINDSTEDT_DENDRITIC_CELL_MATURATION_A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDSTEDT_DENDRITIC_CELL_MATURATION_A","description":"Maturation of monocyte-derived dendritic cells (DC) in response to inflammatory stimuli: genes up-regulated only at 8 hr after the stimulation (cluster A)."} {"geneset":"LINDSTEDT_DENDRITIC_CELL_MATURATION_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDSTEDT_DENDRITIC_CELL_MATURATION_B","description":"Maturation of monocyte-derived dendritic cells (DC) in response to inflammatory stimuli: genes up-regulated both at 8 hr and 48 hr after the stimulation (cluster B)."} {"geneset":"LINDSTEDT_DENDRITIC_CELL_MATURATION_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDSTEDT_DENDRITIC_CELL_MATURATION_C","description":"Maturation of monocyte-derived dendritic cells (DC) in response to inflammatory stimuli: genes up-regulated only at 48 hr after the stimulation (cluster C)."} {"geneset":"LINDSTEDT_DENDRITIC_CELL_MATURATION_D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINDSTEDT_DENDRITIC_CELL_MATURATION_D","description":"Genes down-regulated during the course of maturation of monocyte-derived dendritic cells (DC) in response to inflammatory stimuli (cluster D)."} {"geneset":"MARSHALL_VIRAL_INFECTION_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSHALL_VIRAL_INFECTION_RESPONSE_UP","description":"Genes up-regulated in the influenza-specific CD8+ [GeneID=925] T lymphocytes from bronchoalveolar lavage (BAL) compared to those from spleen."} {"geneset":"MARSHALL_VIRAL_INFECTION_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSHALL_VIRAL_INFECTION_RESPONSE_DN","description":"Genes down-regulated in the influenza-specific CD8+ [GeneID=925] T lymphocytes from bronchoalveolar lavage (BAL) compared to those from spleen."} {"geneset":"MARTINELLI_IMMATURE_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINELLI_IMMATURE_NEUTROPHIL_UP","description":"Neutrophil-specific genes up-regulated in comparison of immature with mature neutrophils."} {"geneset":"MARTINELLI_IMMATURE_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTINELLI_IMMATURE_NEUTROPHIL_DN","description":"Neutrophil-specific genes down-regulated in comparison of immature with mature neutrophils."} {"geneset":"NICK_RESPONSE_TO_PROC_TREATMENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NICK_RESPONSE_TO_PROC_TREATMENT_UP","description":"Genes up-regulated in neutrophils upon treatment with activated protein C (PROC) [GeneID=5624] of pulmonary inflammation induced by bacterial lipopolysaccharide (LPS)."} {"geneset":"NICK_RESPONSE_TO_PROC_TREATMENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NICK_RESPONSE_TO_PROC_TREATMENT_DN","description":"Genes down-regulated in neutrophils upon treatment with activated protein C (PROC) [GeneID=5624] of pulmonary inflammation induced by bacterial lipopolysaccharide (LPS)."} {"geneset":"NUTT_GBM_VS_AO_GLIOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUTT_GBM_VS_AO_GLIOMA_UP","description":"Top 50 marker genes for glioblastoma multiforme (GBM), a class of high grade glioma."} {"geneset":"NUTT_GBM_VS_AO_GLIOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NUTT_GBM_VS_AO_GLIOMA_DN","description":"Top 50 marker genes for anaplastic oligodendroglioma (AO), a class of high grade glioma."} {"geneset":"PARK_APL_PATHOGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_APL_PATHOGENESIS_UP","description":"Genes up-regulated in U937 cells (acute promyelocytic leukemia, APL) expressing RARA [GeneID=5914] fused with either PML or PLZF [GeneID=5371;7704]."} {"geneset":"PARK_APL_PATHOGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_APL_PATHOGENESIS_DN","description":"Genes down-regulated in U937 cells (acute promyelocytic leukemia, APL) expressing RARA [GeneID=5914] fused with either PML or PLZF [GeneID=5371;7704]."} {"geneset":"PARK_TRETINOIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_TRETINOIN_RESPONSE","description":"Genes up-regulated in U937 cells (acute promyelocytic leukemia, APL) by tretinoin (ATRA) [PubChem=444795]."} {"geneset":"PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION","description":"Genes up-regulated by tretinoin (ATRA) [PubChem=444795] in U937 cells (acute promyelocytic leukemia, APL) made sensitive to the drug by expression of the PML-RARA fusion [GeneID=5371;5914]."} {"geneset":"PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION","description":"Genes up-regulated by tretinoin (ATRA) [PubChem=444795] in U937 cells (acute promyelocytic leukemia, APL) made resistant to the drug by expression of the PLZF-RARA fusion [GeneID=7704, 5914]."} {"geneset":"ZHANG_INTERFERON_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_INTERFERON_RESPONSE","description":"Interferon-inducible genes up-regulated in A549 cells (lung cancer) infected with a respiratory syncytial virus (RSV) that had its NS1 [GeneID=1494468] gene knocked down by RNAi."} {"geneset":"WU_ALZHEIMER_DISEASE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_ALZHEIMER_DISEASE_UP","description":"Genes up-regulated in brain endothelial cells from patients with Alzheimer disease."} {"geneset":"WU_ALZHEIMER_DISEASE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_ALZHEIMER_DISEASE_DN","description":"Genes down-regulated in brain endothelial cells from patients with Alzheimer disease."} {"geneset":"MIZUKAMI_HYPOXIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIZUKAMI_HYPOXIA_UP","description":"Genes up-regulated in DLD-1 cells (colon cancer) in response to hypoxia; might not be direct targets of HIF1A [GeneID=3091]."} {"geneset":"MIZUKAMI_HYPOXIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIZUKAMI_HYPOXIA_DN","description":"Genes down-regulated in DLD-1 cells (colon cancer) in response to hypoxia; might not be direct targets of HIF1A [GeneID=3091]."} {"geneset":"YOSHIMURA_MAPK8_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YOSHIMURA_MAPK8_TARGETS_UP","description":"Genes up-regulated in vascular smooth muscle cells (VSMC) by MAPK8 (JNK1) [GeneID=5599]."} {"geneset":"YOSHIMURA_MAPK8_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YOSHIMURA_MAPK8_TARGETS_DN","description":"Genes down-regulated in vascular smooth muscle cells (VSMC) by MAPK8 (JNK1) [GeneID=5599]."} {"geneset":"CHAN_INTERFERON_PRODUCING_DENDRITIC_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHAN_INTERFERON_PRODUCING_DENDRITIC_CELL","description":"Genes up-regulated in spleen interferon-producing dendritic cells (IKDC) compared to plasmacytoid dendritic cells (PDC) and conventional dendritic cells (cDC)."} {"geneset":"WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP","description":"Genes up-regulated in gastric mucosal tissue of mice on 2% cholesterol [PubChem=5997] diet and infected with H. pylori vs those infected with H. pylori while on 0% cholesterol diet."} {"geneset":"WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_DN","description":"Genes down-regulated in gastric mucosal tissue of mice on 2% cholesterol [PubChem=5997] diet and infected with H. pylori vs those infected with H. pylori while on 0% cholesterol diet."} {"geneset":"RAY_TARGETS_OF_P210_BCR_ABL_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAY_TARGETS_OF_P210_BCR_ABL_FUSION_UP","description":"Genes up-regulated in HL-60 cells (acute myeloid leukemia, AML) by expression of p210 BCR-ABL [GeneID=613;25] fusion protein."} {"geneset":"RAY_TARGETS_OF_P210_BCR_ABL_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAY_TARGETS_OF_P210_BCR_ABL_FUSION_DN","description":"Genes down-regulated in HL-60 cells (acute myeloid leukemia, AML) by expression of p210 BCR-ABL [GeneID=613;25] fusion protein."} {"geneset":"RUIZ_TNC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUIZ_TNC_TARGETS_UP","description":"Genes up-regulated in T98G cells (glioblastoma) by TNC [GeneID=3371]."} {"geneset":"RUIZ_TNC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUIZ_TNC_TARGETS_DN","description":"Genes down-regulated in T98G cells (glioblastoma) by TNC [GeneID=3371]."} {"geneset":"RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP","description":"Genes up-regulated in peripheral blood monocytes by CSF2RB (GM-CSF) and IL4 [GeneID=1437;3565]."} {"geneset":"RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN","description":"Genes down-regulated in peripheral blood monocytes by CSF2RB (GM-CSF) and IL4 [GeneID=1437;3565]."} {"geneset":"RUTELLA_RESPONSE_TO_HGF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUTELLA_RESPONSE_TO_HGF_UP","description":"Genes up-regulated in peripheral blood monocytes by HGF [GeneID=3082]."} {"geneset":"RUTELLA_RESPONSE_TO_HGF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUTELLA_RESPONSE_TO_HGF_DN","description":"Genes down-regulated in peripheral blood monocytes by HGF [GeneID=3082]."} {"geneset":"RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP","description":"Genes up-regulated in peripheral blood mononucleocytes by HGF [GeneID=3082] compared to those regulated by CSF2RB (GM-CSF) and IL4 [GeneID=1437;3565]."} {"geneset":"RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN","description":"Genes down-regulated in peripheral blood mononucleocytes by HGF [GeneID=3082] compared to those regulated by CSF2RB (GM-CSF) and IL4 [GeneID=1437;3565]."} {"geneset":"SCHRAETS_MLL_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHRAETS_MLL_TARGETS_UP","description":"Genes up-regulated in fibroblasts from MLL [GeneID=4297] knockout mice."} {"geneset":"SCHRAETS_MLL_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHRAETS_MLL_TARGETS_DN","description":"Genes down-regulated in fibroblasts from MLL [GeneID=4297] knockout mice."} {"geneset":"CHANG_CORE_SERUM_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANG_CORE_SERUM_RESPONSE_UP","description":"Up-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group."} {"geneset":"CHANG_CORE_SERUM_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANG_CORE_SERUM_RESPONSE_DN","description":"Down-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group."} {"geneset":"CHANG_CYCLING_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANG_CYCLING_GENES","description":"Fibroblast serum response genes showing periodic expression during the cell cycle; excluded from the core serum response signature."} {"geneset":"MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP","description":"Up-regulated target genes shared by acute myeloid leukemia (AML) translocation products PML RARA [GeneID=5371;5914], AML1 ETO [GeneID=861;862], and PLZF RARA [GeneID=5914;7704]."} {"geneset":"MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_DN","description":"Down-regulated target genes shared by acute myeloid leukemia (AML) translocation products PML RARA [GeneID=5371;5914], AML1 ETO [GeneID=861;862], and PLZF RARA [GeneID=5914;7704]."} {"geneset":"ROSS_LEUKEMIA_WITH_MLL_FUSIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROSS_LEUKEMIA_WITH_MLL_FUSIONS","description":"Top 100 probe sets associated with MLL fusions [GeneID=4297] irrespective of the lineage of the pediatric acute leukemia."} {"geneset":"VANASSE_BCL2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANASSE_BCL2_TARGETS_UP","description":"Genes up-regulated in primary B lymphocytes engineered to overexpress BCL2 [GeneID=12043]."} {"geneset":"VANASSE_BCL2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANASSE_BCL2_TARGETS_DN","description":"Genes down-regulated in primary B lymphocytes engineered to overexpress BCL2 [GeneID=12043]."} {"geneset":"VANTVEER_BREAST_CANCER_ESR1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANTVEER_BREAST_CANCER_ESR1_UP","description":"Up-regulated genes from the optimal set of 550 markers discriminating breast cancer samples by ESR1 [GeneID=2099] expression: ER(+) vs ER(-) tumors."} {"geneset":"VANTVEER_BREAST_CANCER_ESR1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANTVEER_BREAST_CANCER_ESR1_DN","description":"Down-regulated genes from the optimal set of 550 markers discriminating breast cancer samples by ESR1 [GeneID=2099] expression: ER(+) vs ER(-) tumors."} {"geneset":"VANTVEER_BREAST_CANCER_BRCA1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANTVEER_BREAST_CANCER_BRCA1_UP","description":"Up-regulated genes from the optimal set of 100 markers discriminating ER(-) breast cancer tumors by BRCA1 [GeneID=672] mutation status."} {"geneset":"VANTVEER_BREAST_CANCER_BRCA1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANTVEER_BREAST_CANCER_BRCA1_DN","description":"Down-regulated genes from the optimal set of 100 markers discriminating ER(-) breast cancer tumors by BRCA1 [GeneID=672] mutation status."} {"geneset":"WALLACE_JAK2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WALLACE_JAK2_TARGETS_UP","description":"Genes up-regulated more than 7-fold by expressing JAK2 [GeneID=3717] in the JAK2 null cell line."} {"geneset":"AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP","description":"Up-regulated genes whose expression correlates with copy number gains in pancreatic adenocarcinoma cell lines and primary tumor specimens."} {"geneset":"AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN","description":"Down-regulated genes whose expression correlates with copy number losses in pancreatic adenocarcinoma cell lines and primary tumor specimens."} {"geneset":"SWEET_LUNG_CANCER_KRAS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SWEET_LUNG_CANCER_KRAS_UP","description":"Genes up-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]."} {"geneset":"SWEET_LUNG_CANCER_KRAS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SWEET_LUNG_CANCER_KRAS_DN","description":"Genes down-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]."} {"geneset":"SWEET_KRAS_ONCOGENIC_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SWEET_KRAS_ONCOGENIC_SIGNATURE","description":"Genes that contributed maximally to the GSEA score of the up-regulated gene set from the KrasLA mouse model in two human lung cancer expression data sets comparing mutant vs normal KRAS [GeneID=3845]."} {"geneset":"HINATA_NFKB_TARGETS_KERATINOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HINATA_NFKB_TARGETS_KERATINOCYTE_UP","description":"Genes up-regulated in primary keratinocytes by expression of p50 (NFKB1) and p65 (RELA) [GeneID=4790;5970] components of NFKB."} {"geneset":"HINATA_NFKB_TARGETS_KERATINOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HINATA_NFKB_TARGETS_KERATINOCYTE_DN","description":"Genes down-regulated in primary keratinocytes by expression of p50 (NFKB1) and p65 (RELA) [GeneID=4790;5970] components of NFKB."} {"geneset":"HINATA_NFKB_TARGETS_FIBROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HINATA_NFKB_TARGETS_FIBROBLAST_UP","description":"Genes up-regulated in primary fibroblast cells by expression of p50 (NFKB1) and p65 (RELA) [GeneID=4790;5970] components of NFKB."} {"geneset":"HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_UP","description":"Genes up-regulated during differentiation from pre-BI to large pre-BII lymphocyte."} {"geneset":"HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN","description":"Genes down-regulated during differentiation from pre-BI to large pre-BII lymphocyte."} {"geneset":"HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP","description":"Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte."} {"geneset":"HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_DN","description":"Genes down-regulated during differentiation from large pre-BII to small pre-BII lymphocyte."} {"geneset":"HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_UP","description":"Genes up-regulated during differentiation from small pre-BII to immature B lymphocyte."} {"geneset":"HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_DN","description":"Genes down-regulated during differentiation from small pre-BII to immature B lymphocyte."} {"geneset":"HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP","description":"Genes up-regulated during differentiation of immature to mature B lymphocyte."} {"geneset":"HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_DN","description":"Genes down-regulated during differentiation of immature to mature B lymphocyte."} {"geneset":"HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_UP","description":"Genes up-regulated in bone marrow hematopoietic stem cells (HSC, CD34+ [GeneID=947]) from patients with low risk of myelodysplastic syndrome (MDS) compared with healthy controls."} {"geneset":"HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_DN","description":"Genes down-regulated in bone marrow hematopoietic stem cells (HSC, CD34+ [GeneID=947]) from patients with low risk of myelodysplastic syndrome (MDS) compared with healthy controls."} {"geneset":"HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP","description":"Genes up-regulated in bone marrow hematopoietic stem cells (HSC, CD34+ [GeneID=947]) from patients with high risk of myelodysplastic syndrome (MDS) compared with healthy controls."} {"geneset":"HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_DN","description":"Genes down-regulated in bone marrow hematopoietic stem cells (HSC, CD34+ [GeneID=947]) from patients with high risk of myelodysplastic syndrome (MDS) compared with healthy controls."} {"geneset":"HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_UP","description":"Genes up-regulated in bone marrow hematopoietic stem cells (HSC, CD34+ [GeneID=947]) from patients with high risk of myelodysplastic syndrom (MDS) compared to the low risk patients."} {"geneset":"HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_DN","description":"Genes down-regulated in bone marrow hematopoietic stem cells (HSC, CD34+ [GeneID=947]) from patients with high risk of myelodysplastic syndrom (MDS) compared to the low risk patients."} {"geneset":"LEE_EARLY_T_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_EARLY_T_LYMPHOCYTE_UP","description":"Genes up-regulated at early stages of progenitor T lymphocyte maturation compared to the late stages."} {"geneset":"LEE_EARLY_T_LYMPHOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_EARLY_T_LYMPHOCYTE_DN","description":"Genes down-regulated at early stages of progenitor T lymphocyte maturation compared to the late stages."} {"geneset":"LEE_INTRATHYMIC_T_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_INTRATHYMIC_T_PROGENITOR","description":"Genes enriched in the intrathymic T progenitor (ITTP) cells compared to all other T lymphocyte differentiation stages."} {"geneset":"LEE_DOUBLE_POLAR_THYMOCYTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_DOUBLE_POLAR_THYMOCYTE","description":"Genes enriched in the double polar (DP) thymocyte compared to all other T lymphocyte differentiation stages."} {"geneset":"LEE_SP4_THYMOCYTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_SP4_THYMOCYTE","description":"Genes enriched in the single positive 4 (SP4) thymocytes compared to all other T lymphocyte differentiation stages."} {"geneset":"LEE_RECENT_THYMIC_EMIGRANT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_RECENT_THYMIC_EMIGRANT","description":"Candidate genes specific for recent thymic emigrants (RTEs)."} {"geneset":"LEE_NAIVE_T_LYMPHOCYTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_NAIVE_T_LYMPHOCYTE","description":"Genes enriched in the naive circulating T lymphocytes compared to the earlier differentiation stages."} {"geneset":"LEE_DIFFERENTIATING_T_LYMPHOCYTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_DIFFERENTIATING_T_LYMPHOCYTE","description":"Genes enriched at every T lymphocyte differentiation stage compared to the early passage fetal thymic stromal cultures (TSC)."} {"geneset":"LI_WILMS_TUMOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_WILMS_TUMOR","description":"'Wilm's tumor signature': genes highly expressed in Wilm's tumor samples compared to normal fetal kidney and a heterologous tumor, Burkit lymphoma."} {"geneset":"FINAK_BREAST_CANCER_SDPP_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FINAK_BREAST_CANCER_SDPP_SIGNATURE","description":"Genes in the stroma-derived prognostic predictor of breast cancer disease outcome."} {"geneset":"SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6","description":"Cluster 6 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts poor survival outcome."} {"geneset":"SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4","description":"Cluster 4 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome."} {"geneset":"BRUNEAU_SEPTATION_ATRIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUNEAU_SEPTATION_ATRIAL","description":"Genes for which mutations result in atrial septation defects, a major class of congenital heart disease."} {"geneset":"SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A5","description":"Cluster 5 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome."} {"geneset":"BRUNEAU_SEPTATION_VENTRICULAR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUNEAU_SEPTATION_VENTRICULAR","description":"Genes for which mutations result in developmental defects in ventricular septation and atrioventricular cushion formation, a major class of congenital heart disease."} {"geneset":"BRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS","description":"Genes for which mutations result in developmental defects in the great vessels formation and valvulogenesis, a major class of congenital heart disease."} {"geneset":"ZHANG_TLX_TARGETS_36HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_TLX_TARGETS_36HR_UP","description":"Genes up-regulated in neural stem cells (NSC) at 36 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]."} {"geneset":"ZHANG_TLX_TARGETS_36HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_TLX_TARGETS_36HR_DN","description":"Genes down-regulated in neural stem cells (NSC) at 36 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]."} {"geneset":"ZHANG_TLX_TARGETS_60HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_TLX_TARGETS_60HR_UP","description":"Genes up-regulated in neural stem cells (NSC) at 60 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]."} {"geneset":"ZHANG_TLX_TARGETS_60HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_TLX_TARGETS_60HR_DN","description":"Genes down-regulated in neural stem cells (NSC) at 60 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]."} {"geneset":"ZHANG_TLX_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_TLX_TARGETS_DN","description":"Genes down-regulated in neural stem cells (NSC) at both 36 h and 60 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]."} {"geneset":"ZHANG_TLX_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_TLX_TARGETS_UP","description":"Genes up-regulated in neural stem cells (NSC) at both 36 h and 60 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]."} {"geneset":"MELLMAN_TUT1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MELLMAN_TUT1_TARGETS_UP","description":"Genes up-regulated in HEK293 cells (embryo kidney) after knockdown of TUT1 [GeneID=64852] by RNAi."} {"geneset":"MELLMAN_TUT1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MELLMAN_TUT1_TARGETS_DN","description":"Genes down-regulated in HEK293 cells (embryo kidney) after knockdown of TUT1 [GeneID=64852] by RNAi."} {"geneset":"HAN_SATB1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAN_SATB1_TARGETS_UP","description":"Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [GeneID=6304] by RNAi."} {"geneset":"HAN_SATB1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAN_SATB1_TARGETS_DN","description":"Genes down-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [GeneID=6304] by RNAi."} {"geneset":"SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12","description":"Cluster 12 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome."} {"geneset":"COLINA_TARGETS_OF_4EBP1_AND_4EBP2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COLINA_TARGETS_OF_4EBP1_AND_4EBP2","description":"Genes up-regulated in MEF cells (embryonic fibroblast) with double knockout of the translation repressors 4EBP1 [GeneID=1978] and 4EBP2 [GeneID=1979]."} {"geneset":"CHEN_METABOLIC_SYNDROM_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_METABOLIC_SYNDROM_NETWORK","description":"Genes forming the macrophage-enriched metabolic network (MEMN) claimed to have a causal relationship with the metabolic syndrom traits."} {"geneset":"MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_UP","description":"Up-regulated 'cooperation response genes': responded synergystically to the combination of mutant TP53 and HRAS [GeneID=7157;3265] in YAMC cells (colon)."} {"geneset":"MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN","description":"Down-regulated 'cooperation response genes': responded synergystically to the combination of mutant TP53 and HRAS [GeneID=7157;3265] in YAMC cells (colon)."} {"geneset":"MIKKELSEN_PLURIPOTENT_STATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_PLURIPOTENT_STATE_UP","description":"Genes up-regulated in the induced pluripotent cells (iPS) and embryonic stem cells (ES) compared to the parental lineage-committed and partially reprogrammed cell lines."} {"geneset":"MIKKELSEN_PLURIPOTENT_STATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_PLURIPOTENT_STATE_DN","description":"Genes down-regulated in the induced pluripotent cells (iPS) and embryonic stem cells (ES) compared to the parental lineage-committed and partially reprogrammed cell lines."} {"geneset":"MIKKELSEN_DEDIFFERENTIATED_STATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_DEDIFFERENTIATED_STATE_UP","description":"Genes up-regulated in partially reprogrammed and pluripotent cell populations (induced, iPS; and embryonic stem cells, ES) compared to parental lineage-commited cell lines."} {"geneset":"MIKKELSEN_DEDIFFERENTIATED_STATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_DEDIFFERENTIATED_STATE_DN","description":"Genes down-regulated in partially reprogrammed and pluripotent cell populations (induced, iPS; and embryonic stem cells, ES) compared to parental lineage-commited cell lines."} {"geneset":"MIKKELSEN_PARTIALLY_REPROGRAMMED_TO_PLURIPOTENCY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_PARTIALLY_REPROGRAMMED_TO_PLURIPOTENCY","description":"Genes up-regulated in cells that have been partially reprogrammed to pluripotency: comparison with the parental lineage-committed cell lines, fully reprogrammed stem cells, and embryonic stem cells."} {"geneset":"ELLWOOD_MYC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELLWOOD_MYC_TARGETS_UP","description":"Genes up-regulated in transgenic mice expressing human MYC [GeneID=4609] in prostate."} {"geneset":"ELLWOOD_MYC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELLWOOD_MYC_TARGETS_DN","description":"Genes down-regulated in transgenic mice expressing human MYC [GeneID=4609] in prostate."} {"geneset":"SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM","description":"Direct targets of IRF4 [GeneID=3662] that constitute a multiple myeloma program."} {"geneset":"SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE","description":"IRF4 [GeneID=3662] target genes up-regulated in primary myeloma vs. mature B lymphocytes."} {"geneset":"SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE","description":"IRF4 [GeneID=3662] target genes up-regulated in plasma cells compared to mature B lymphocytes."} {"geneset":"SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE","description":"IRF4 [GeneID=3662] target genes induced after activation of primary B lymphocytes by anti-IgM crosslinking."} {"geneset":"SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL","description":"IRF4 [GeneID=3662] target genes up-regulated in plasmacytoid dendritic cells compared to monocytes."} {"geneset":"HSIAO_HOUSEKEEPING_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HSIAO_HOUSEKEEPING_GENES","description":"Housekeeping genes identified as expressed across 19 normal tissues."} {"geneset":"MEISSNER_ES_ICP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_ES_ICP_WITH_H3K4ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in ES cells (embryonic stem)."} {"geneset":"MEISSNER_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing histone trimethylation marks at K4 (H3K4me3) and K27 (H3K27me3)ES cells (embryonic stem)."} {"geneset":"MEISSNER_NPC_HCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_NPC_HCP_WITH_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing the H3K27 tri-methylation (H3K27me3) mark in neural precursor cells (NPC)."} {"geneset":"MEISSNER_NPC_ICP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_NPC_ICP_WITH_H3K4ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural precursor cells (NPC)."} {"geneset":"MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation marks at k4 (H3K4me3) and K27 ((H3K27me3) in neural precursor cells (NPC)."} {"geneset":"MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED","description":"Genes with high-CpG-density promoters (HCP) that have no histone H3 methylation marks in neural precursor cells (NPC)."} {"geneset":"MEISSNER_NPC_ICP_WITH_H3_UNMETHYLATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_NPC_ICP_WITH_H3_UNMETHYLATED","description":"Genes with intermediate-CpG-density promoters (ICP) that have no histone H3 methylation marks in neural precursor cells (NPC)."} {"geneset":"MEISSNER_BRAIN_HCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_BRAIN_HCP_WITH_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing the H3K27 tri-methylation (H3K27me3) mark in brain."} {"geneset":"MEISSNER_BRAIN_ICP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_BRAIN_ICP_WITH_H3K4ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in brain."} {"geneset":"MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation at K4 (H3K4me2) and trimethylation at K27 (H3K27me3) in brain."} {"geneset":"MEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED","description":"Genes with high-CpG-density promoters (HCP) that have no histone H3 methylation marks in brain."} {"geneset":"TAVAZOIE_METASTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAVAZOIE_METASTASIS","description":"Putative metastasis genes: up-regulated in metastatic cell lines LM2 (lung) and BoM2 (bone) relative to the parental MDA-MB-231 line (breast adenocarcinoma)."} {"geneset":"WENDT_COHESIN_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WENDT_COHESIN_TARGETS_UP","description":"Cohesin targets identified by ChIP-chip which were up-regulated after knockdown of CTCF and RAD21 [GeneID=10664;5885] by RNAi."} {"geneset":"FERRANDO_HOX11_NEIGHBORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FERRANDO_HOX11_NEIGHBORS","description":"Nearest neighbors of HOX11 [GeneID=3195], based on the close agreement of their expression profiles with that of HOX11 in pediatric T cell acute lymphoblastic leukemia (T-ALL)."} {"geneset":"CHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_HD_MTX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_HD_MTX_UP","description":"Genes specifically up-regulated in pediatric acute lymphoblastic leukemia (ALL) patients by mercaptopurine [PubChem=667490] and high dose methotrexate (HDMTX) [PubChem=4112]."} {"geneset":"CHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_HD_MTX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_HD_MTX_DN","description":"Genes specifically down-regulated in pediatric acute lymphoblastic leukemia (ALL) patients by mercaptopurine [PubChem=667490] and high dose methotrexate (HDMTX) [PubChem=4112]."} {"geneset":"ZHAN_EARLY_DIFFERENTIATION_GENES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_EARLY_DIFFERENTIATION_GENES_UP","description":"B lymphocyte early differentiation genes (EDG): top genes up-regulated in tonsil B lymphocytes (TBC) compared to the tonsil plasma cells (TPC)."} {"geneset":"ZHAN_EARLY_DIFFERENTIATION_GENES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_EARLY_DIFFERENTIATION_GENES_DN","description":"B lymphocyte early differentiation genes (EDG): top genes down-regulated in tonsil B lymphocytes (TBC) compared to the tonsil plasma cells (TPC)."} {"geneset":"MILI_PSEUDOPODIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MILI_PSEUDOPODIA","description":"Transcripts significantly enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to both chemotactic (lysophosphatidic acid, LPA [PubChem=3988]) and haptotactic (fibronectin, FN1 [GeneID=2335) migratory stimuli."} {"geneset":"MILI_PSEUDOPODIA_CHEMOTAXIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MILI_PSEUDOPODIA_CHEMOTAXIS_UP","description":"Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to the chemotactic migration stimulus by lysophosphatidic acid (LPA) [PubChem=3988]."} {"geneset":"MILI_PSEUDOPODIA_CHEMOTAXIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MILI_PSEUDOPODIA_CHEMOTAXIS_DN","description":"Transcripts depleted in pseudopodia of NIH/3T3 cells (fibroblast) in response to the chemotactic migration stimulus by lysophosphatidic acid (LPA) [PubChem=3988]."} {"geneset":"MILI_PSEUDOPODIA_HAPTOTAXIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MILI_PSEUDOPODIA_HAPTOTAXIS_UP","description":"Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin, FN1 [GeneID=2335]."} {"geneset":"MILI_PSEUDOPODIA_HAPTOTAXIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MILI_PSEUDOPODIA_HAPTOTAXIS_DN","description":"Transcripts depleted from pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin, FN1 [GeneID=2335]."} {"geneset":"LIU_VAV3_PROSTATE_CARCINOGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_VAV3_PROSTATE_CARCINOGENESIS_UP","description":"Selected genes up-regulated in prostate tumors developed by transgenic mice overexpressing VAV3 [GeneID=10451] in prostate epithelium."} {"geneset":"LIU_VAV3_PROSTATE_CARCINOGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_VAV3_PROSTATE_CARCINOGENESIS_DN","description":"Selected genes down-regulated in prostate tumors developed by transgenic mice overexpressing VAV3 [GeneID=10451] in prostate epithelium."} {"geneset":"CROONQUIST_IL6_DEPRIVATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROONQUIST_IL6_DEPRIVATION_UP","description":"Genes up-regulated in the ANBL-6 cell line (multiple myeloma, MM) after withdrawal of IL6 [GeneID=3569]."} {"geneset":"CROONQUIST_IL6_DEPRIVATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROONQUIST_IL6_DEPRIVATION_DN","description":"Genes down-regulated in the ANBL-6 cell line (multiple myeloma, MM) after withdrawal of IL6 [GeneID=3569]."} {"geneset":"CROONQUIST_STROMAL_STIMULATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROONQUIST_STROMAL_STIMULATION_UP","description":"Genes up-regulated in ANBL-6 cell line (multiple myeloma, MM) co-cultured with bone marrow stromal cells compared to those grown in the presence of IL6 [GeneID=3569]."} {"geneset":"CROONQUIST_STROMAL_STIMULATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROONQUIST_STROMAL_STIMULATION_DN","description":"Genes down-regulated in ANBL-6 cell line (multiple myeloma, MM) co-cultured with bone marrow stromal cells compared to those grown in the presence of IL6 [GeneID=3569]."} {"geneset":"CROONQUIST_NRAS_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROONQUIST_NRAS_SIGNALING_UP","description":"Genes up-regulated in ANBL-6 cell line (multiple myeloma, MM) expressing a constantly active form of NRAS [GeneID=4893] off a plasmid vector compared to those grown in the presence of IL6 [GeneID=3569]."} {"geneset":"CROONQUIST_NRAS_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROONQUIST_NRAS_SIGNALING_DN","description":"Genes down-regulated in ANBL-6 cell line (multiple myeloma, MM) expressing a constantly active form of NRAS [GeneID=4893] off a plasmid vector compared to those grown in the presence of IL6 [GeneID=3569]."} {"geneset":"CROONQUIST_NRAS_VS_STROMAL_STIMULATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROONQUIST_NRAS_VS_STROMAL_STIMULATION_UP","description":"Genes up-regulated in ANBL-6 cell line (multiple myeloma, MM) expressing an activated form of NRAS [GeneID=4893] off a plasmid vector compared to those co-cultured with bone marrow stromal cells."} {"geneset":"CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN","description":"Genes down-regulated in ANBL-6 cell line (multiple myeloma, MM) expressing an activated form of NRAS [GeneID=4893] off a plasmid vector compared to those co-cultured with bone marrow stromal cells."} {"geneset":"IRITANI_MAD1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IRITANI_MAD1_TARGETS_UP","description":"Genes up-regulated by overexpression of MAD1 [GeneID=4084] in primary thymocytes from RAG2 [GeneID=5897] knockout mice."} {"geneset":"IRITANI_MAD1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IRITANI_MAD1_TARGETS_DN","description":"Genes down-regulated by overexpression of MAD1 [GeneID=4084] in primary thymocytes from RAG2 [GeneID=5897] knockout mice."} {"geneset":"ZHAN_LATE_DIFFERENTIATION_GENES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_LATE_DIFFERENTIATION_GENES_UP","description":"B lymphocyte late differentiation genes (LDG): top genes up-regulated in plasma cells from tonsils (TPC) compared to those from bone marrow (BPC)."} {"geneset":"ZHAN_LATE_DIFFERENTIATION_GENES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_LATE_DIFFERENTIATION_GENES_DN","description":"B lymphocyte late differentiation genes (LDG): top genes down-regulated in plasma cells from tonsils (TPC) compared to those from bone marrow (BPC)."} {"geneset":"ZHAN_VARIABLE_EARLY_DIFFERENTIATION_GENES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_VARIABLE_EARLY_DIFFERENTIATION_GENES_UP","description":"The vEDG up-regulated set: most variable early differentiation genes (EDG) with similar expression patterns in tonsil B lymphocytes (TBC) and multiple myeloma (MM) cells compared to the plasma cells from tonsil (TPC) and bone marrow (BPC)."} {"geneset":"ZHAN_VARIABLE_EARLY_DIFFERENTIATION_GENES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_VARIABLE_EARLY_DIFFERENTIATION_GENES_DN","description":"The vEDG down-regulated set: most variable early differentiation genes (EDG) with similar expression patterns in tonsil B lymphocytes (TBC) and multiple myeloma (MM) cells compared to the plasma cells from tonsil (TPC) and bone marrow (BPC)."} {"geneset":"ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP","description":"The v1LDG up-regulated set: most variable late differentiation genes (LDG) with similar expression patterns in tonsil plasma cells (TPC) and multiple myeloma (MM) samples."} {"geneset":"ZHAN_V1_LATE_DIFFERENTIATION_GENES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_V1_LATE_DIFFERENTIATION_GENES_DN","description":"The v1LDG down-regulated set: most variable late differentiation genes (LDG) with similar expression patterns in tonsil plasma cells (TPC) and multiple myeloma (MM) samples."} {"geneset":"ISHIDA_E2F_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ISHIDA_E2F_TARGETS","description":"Genes up-regulated in MEF cells (embryonic fibroblast) after expression of E2F1 or E2F2 [GeneID=1869;1870]."} {"geneset":"ROME_INSULIN_TARGETS_IN_MUSCLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROME_INSULIN_TARGETS_IN_MUSCLE_UP","description":"Genes up-regulated by 3 h of euglycemic hyperinsulinemic clamp in the vastus lateralis muscle of healthy lean subjects."} {"geneset":"ROME_INSULIN_TARGETS_IN_MUSCLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROME_INSULIN_TARGETS_IN_MUSCLE_DN","description":"Genes down-regulated by 3 h of euglycemic hyperinsulinemic clamp in the vastus lateralis muscle of healthy lean subjects."} {"geneset":"VALK_AML_CLUSTER_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_1","description":"Top 40 genes from cluster 1 of acute myeloid leukemia (AML) expression profile; 57% of the samples are FAB M1 subtype, 43% have 11q23 abnormalities, and 36% have up-regulated EVI1 [GeneID=2122] expression."} {"geneset":"VALK_AML_CLUSTER_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_2","description":"Top 40 genes from cluster 2 of acute myeloid leukemia (AML) expression profile; 71% of the samples are FAB M4 or M5 subtypes, and 82% bear internal tundem duplications in FLT3 [GeneID=2322]."} {"geneset":"VALK_AML_CLUSTER_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_3","description":"Top 40 genes from cluster 3 of acute myeloid leukemia (AML) expression profile; 84% of the samples are FAB M1 or M2 subtypes, 52% bear intern tandem duplication in FLT3 [GeneID=2322]."} {"geneset":"VALK_AML_CLUSTER_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_4","description":"Top 40 genes from cluster 4 of acute myeloid leukemia (AML) expression profile; 87% of the samples are FAB M1 subtype, 53% bear mutations in CEBPA [GeneID=1050]."} {"geneset":"VALK_AML_CLUSTER_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_5","description":"Top 40 genes from cluster 5 of acute myeloid leukemia (AML) expression profile; 96% of the samples are FAB M4 or M5 subtype."} {"geneset":"VALK_AML_CLUSTER_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_6","description":"Top 40 genes from cluster 6 of acute myeloid leukemia (AML) expression profile; all samples are FAB M1 or M2 subtypes and all samples have internal tundem duplication of FLT3 [GeneID=2322]."} {"geneset":"VALK_AML_CLUSTER_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_7","description":"Top 40 genes from cluster 7 of acute myeloid leukemia (AML) expression profile; 61% of the samples are FAB M1 or M2 subtype."} {"geneset":"VALK_AML_CLUSTER_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_8","description":"Top 40 genes from cluster 8 of aculte myeloid leukemia (AML) expression profile; 69% of the samples are FAB M2 subtype."} {"geneset":"VALK_AML_CLUSTER_9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_9","description":"Top 40 genes from cluster 9 of acute myeloid leukemia (AML) expression profile; 87% of the samples are FAB M4 or M5 subtype, all have inv(16) inversion producing the CBFB-MYH11 fusion [GeneID=865;4629]; indicate good survival."} {"geneset":"VALK_AML_CLUSTER_10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_10","description":"Top 40 genes from cluster 10 of acute myeloid leukemia (AML) expression profile; 41% of the samples are FAB M1 subtype, 45% have up-regulated EVI1 [GeneID=2122] expression; indicate poor survival."} {"geneset":"VALK_AML_CLUSTER_11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_11","description":"Top 40 genes from cluster 11 of acute myeloid leukemia (AML) expression profile; 67% of the samples are FAB M4 or M5."} {"geneset":"VALK_AML_CLUSTER_12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_12","description":"Top 40 genes from cluster 12 of acute myeloid leukemia (AML) expression profile; 89% of the samples are FAB M3 subtype, 95% bear the t(15;17) translocation, all have the PML-RARA fusion [GeneID=5371;5914]; indicate good survival."} {"geneset":"VALK_AML_CLUSTER_13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_13","description":"Top 40 genes from cluster 13 of acute myeloid leukemia (AML) expression profile; 91% of the samples are FAB M2 subtype, all bear the t(8;21) translocation producing the AML1-ETO fusion [GeneID=861;862]; indicate good survival."} {"geneset":"VALK_AML_CLUSTER_15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_15","description":"Top 40 genes from cluster 15 of acute myeloid leukemia (AML) expression profile; 88% of the samples are FAB M1 or M2 subtype, 63% have mutations in CEBPA [GeneID=1050]."} {"geneset":"VALK_AML_CLUSTER_16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_CLUSTER_16","description":"Top 40 genes from cluster 16 of acute myeloid leukemia (AML) expression profile; 81% of the samples are FAB M5 subtype, 45% have 11q23 abnormalities."} {"geneset":"VALK_AML_WITH_T_8_21_TRANSLOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_WITH_T_8_21_TRANSLOCATION","description":"Genes that best predicted acute myeloid leukemia (AML) with the t(8;21) translocation producing the AML1-ETO fusion [GeneID=861;862]."} {"geneset":"VALK_AML_WITH_11Q23_REARRANGED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_WITH_11Q23_REARRANGED","description":"Genes that best predicted acute myeloid leukemia (AML) with the 11q23 rearrangements."} {"geneset":"VALK_AML_WITH_EVI1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_WITH_EVI1","description":"Genes that best predicted acute myeloid leukemia (AML) with the up-regulated expression of EVI1 [GeneID=2122]."} {"geneset":"VALK_AML_WITH_CEBPA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_WITH_CEBPA","description":"Genes that best predicted acute myeloid leukemia (AML) with mutations in CEBPA [GeneID=1050]."} {"geneset":"VALK_AML_WITH_FLT3_ITD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VALK_AML_WITH_FLT3_ITD","description":"Genes that best predicted acute myeloid leukemia (AML) with internal tandem duplications (IDT) in FLT3 [GeneID=2322]."} {"geneset":"JISON_SICKLE_CELL_DISEASE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JISON_SICKLE_CELL_DISEASE_UP","description":"Genes up-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects."} {"geneset":"JISON_SICKLE_CELL_DISEASE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JISON_SICKLE_CELL_DISEASE_DN","description":"Genes down-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects."} {"geneset":"POOLA_INVASIVE_BREAST_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POOLA_INVASIVE_BREAST_CANCER_UP","description":"Genes up-regulated in atypical ductal hyperplastic tissues from patients with (ADHC) breast cancer vs those without the cancer (ADH)."} {"geneset":"POOLA_INVASIVE_BREAST_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POOLA_INVASIVE_BREAST_CANCER_DN","description":"Genes down-regulated in atypical ductal hyperplastic tissues from patients with (ADHC) breast cancer vs those without the cancer (ADH)."} {"geneset":"DING_LUNG_CANCER_MUTATED_RECURRENTLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DING_LUNG_CANCER_MUTATED_RECURRENTLY","description":"The lung adenocarcinoma TSP (tumor sequencing project) genes bearing recurrent somatic mutations."} {"geneset":"DING_LUNG_CANCER_BY_MUTATION_RATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DING_LUNG_CANCER_BY_MUTATION_RATE","description":"The lung adenocarcinoma TSP (tumor sequencing project) genes mutations in which show positive correlation with the higher overall mutation rate."} {"geneset":"TCGA_GLIOBLASTOMA_MUTATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCGA_GLIOBLASTOMA_MUTATED","description":"Genes significantly mutated in 91 glioblastoma samples."} {"geneset":"CHEN_LIVER_METABOLISM_QTL_CIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEN_LIVER_METABOLISM_QTL_CIS","description":"Cis-regulated expression quantitative loci (cis-eQTL) in the liver that contribute to metabolic quantitative traits (weight, fat mass, and plasma glucose and cholesterol levels)."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP","description":"Up-regulated genes in hepatocellular carcinoma (HCC) subclass G1, defined by unsupervised clustering"} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN","description":"Down-regulated genes in hepatocellular carcinoma (HCC) subclass G1, defined by unsupervised clustering"} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G2","description":"Genes in hepatocellular carcinoma (HCC) subclass G2, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP","description":"Up-regulated genes in hepatocellular carcinoma (HCC) subclass G3, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G3_DN","description":"Down-regulated genes in hepatocellular carcinoma (HCC) subclass G3, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN","description":"Down-regulated genes in hepatocellular carcinoma (HCC) subclass G5, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G6_UP","description":"Up-regulated genes in hepatocellular carcinoma (HCC) subclass G6, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G6_DN","description":"Down-regulated genes in hepatocellular carcinoma (HCC) subclass G6, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G12_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G12_UP","description":"Up-regulated genes in hepatocellular carcinoma (HCC) subclass G12, defined by unsupervised clustering"} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G12_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G12_DN","description":"Down-regulated genes in hepatocellular carcinoma (HCC) subclass G12, defined by unsupervised clustering"} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP","description":"Up-regulated genes in hepatocellular carcinoma (HCC) subclass G23, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G23_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G23_DN","description":"Down-regulated genes in hepatocellular carcinoma (HCC) subclass G23, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G56_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G56_UP","description":"Up-regulated genes in hepatocellular carcinoma (HCC) subclass G56, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN","description":"Down-regulated genes in hepatocellular carcinoma (HCC) subclass G56, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP","description":"Up-regulated genes in hepatocellular carcinoma (HCC) subclass G123, defined by unsupervised clustering."} {"geneset":"BOYAULT_LIVER_CANCER_SUBCLASS_G123_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYAULT_LIVER_CANCER_SUBCLASS_G123_DN","description":"Down-regulated genes in hepatocellular carcinoma (HCC) subclass G123, defined by unsupervised clustering."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP","description":"Top 200 marker genes up-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [GeneID=1499]."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN","description":"Top 200 marker genes down-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [GeneID=1499]."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP","description":"Top 200 marker genes up-regulated in the 'proliferation' subclass of hepatocellular carcinoma (HCC); characterized by increased proliferation, high levels of serum AFP [GeneID=174], and chromosomal instability."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN","description":"Top 200 marker genes down-regulated in the 'proliferation' subclass of hepatocellular carcinoma (HCC); characterized by increased proliferation, high levels of serum AFP [GeneID=174], and chromosomal instability."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP","description":"All marker genes up-regulated in the 'interferon' subclass of hepatocellular carcinoma (HCC)."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_DN","description":"All marker genes down-regulated in the 'interferon' subclass of hepatocellular carcinoma (HCC)."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_UP","description":"Marker genes up-regulated in the 'chromosome 7 polysomy' subclass of hepatocellular carcinoma (HCC); characterized by polysomy of chromosome 7 and by a lack of gains of chromosome 8q."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_DN","description":"Marker genes down-regulated in the 'chromosome 7 polysomy' subclass of hepatocellular carcinoma (HCC); characterized by polysomy of chromosome 7 and by a lack of gains of chromosome 8q."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP","description":"Marker genes up-regulated in the 'unannotated' subclass of hepatocellular carcinoma (HCC) samples."} {"geneset":"CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN","description":"Marker genes down-regulated in the 'unannotated' subclass of hepatocellular carcinoma (HCC) samples."} {"geneset":"COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP","description":"'Late-TGFB1 signature': genes overexpressed in primary hepatocytes at a late phase of TGFB1 [GeneID=7040] treatment; is associated with a more invasive phenotype."} {"geneset":"COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN","description":"'Early-TGFB1 signature': genes overexpressed in primary hepatocytes at an early phase of TGFB1 [GeneID=7040] treatment; is associated with a less invasive phenotype."} {"geneset":"HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP","description":"Genes whose expression correlated with higher risk of late recurrence of hepatocellular carcinoma (HCC)."} {"geneset":"HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_DN","description":"Genes whose expression correlated with lower risk of late recurrence of hepatocellular carcinoma (HCC)."} {"geneset":"HOSHIDA_LIVER_CANCER_SURVIVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOSHIDA_LIVER_CANCER_SURVIVAL_UP","description":"Survival signature genes defined in adjacent liver tissue: genes correlated with poor survival of hepatocellular carcinoma (HCC) patients."} {"geneset":"HOSHIDA_LIVER_CANCER_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOSHIDA_LIVER_CANCER_SURVIVAL_DN","description":"Survival signature genes defined in adjacent liver tissue: genes correlated with good survival of hepatocellular carcinoma (HCC) patients."} {"geneset":"KAPOSI_LIVER_CANCER_MET_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAPOSI_LIVER_CANCER_MET_UP","description":"Selected up-regulated MET [GeneID=4233] target genes from a classifier of hepatocellular carcinoma (HCC) cases; associated with poor survival."} {"geneset":"KAPOSI_LIVER_CANCER_MET_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAPOSI_LIVER_CANCER_MET_DN","description":"Selected down-regulated MET [GeneID=4233] target genes from a classifier of hepatocellular carcinoma (HCC) cases; associated with poor survival."} {"geneset":"YAMASHITA_LIVER_CANCER_WITH_EPCAM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMASHITA_LIVER_CANCER_WITH_EPCAM_UP","description":"Up-regulated genes distinguishing hepatocellular carcinoma (HCC) samples positive for EPCAM [GeneID=4072] from the negative ones."} {"geneset":"YAMASHITA_LIVER_CANCER_WITH_EPCAM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMASHITA_LIVER_CANCER_WITH_EPCAM_DN","description":"Down-regulated genes distinguishing hepatocellular carcinoma (HCC) samples positive for EPCAM [GeneID=4072] from the negative ones."} {"geneset":"YAMASHITA_LIVER_CANCER_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMASHITA_LIVER_CANCER_STEM_CELL_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) cells with hepatic stem cell properties."} {"geneset":"YAMASHITA_LIVER_CANCER_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMASHITA_LIVER_CANCER_STEM_CELL_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) cells with hepatic stem cell properties."} {"geneset":"BUDHU_LIVER_CANCER_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BUDHU_LIVER_CANCER_METASTASIS_UP","description":"Genes up-regulated in tumor-adjacent liver tissue, which is asociated with intrahepatic metastasis of hepatocellular carcinoma"} {"geneset":"BUDHU_LIVER_CANCER_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BUDHU_LIVER_CANCER_METASTASIS_DN","description":"Genes down-regulated in tumor-adjacent liver tissue, which is asociated with intrahepatic metastasis of hepatocellular carcinoma"} {"geneset":"LEE_LIVER_CANCER_HEPATOBLAST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_LIVER_CANCER_HEPATOBLAST","description":"Fig.5, Supplementary Fig.2 Genes overexpressed in human hepatocellular carcinoma with hepatoblast property"} {"geneset":"WANG_RECURRENT_LIVER_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RECURRENT_LIVER_CANCER_UP","description":"Genes up-regulated in samples from patients with recurrent hepatocellular carcinoma (HCC)."} {"geneset":"WANG_RECURRENT_LIVER_CANCER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RECURRENT_LIVER_CANCER_DN","description":"Genes down-regulated in samples from patients with recurrent hepatocellular carcinoma (HCC)."} {"geneset":"WOO_LIVER_CANCER_RECURRENCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WOO_LIVER_CANCER_RECURRENCE_UP","description":"Genes positively correlated with recurrence free survival in patients with hepatitis B-related (HBV) hepatocellular carcinoma (HCC)."} {"geneset":"WOO_LIVER_CANCER_RECURRENCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WOO_LIVER_CANCER_RECURRENCE_DN","description":"Genes negatively correlated with recurrence free survival in patients with hepatitis B-related (HBV) hepatocellular carcinoma (HCC)."} {"geneset":"YAMANAKA_GLIOBLASTOMA_SURVIVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMANAKA_GLIOBLASTOMA_SURVIVAL_UP","description":"Genes whose expression most strongly and consistently associated with the long term survival of patients with high grade glioma tumors."} {"geneset":"YAMANAKA_GLIOBLASTOMA_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAMANAKA_GLIOBLASTOMA_SURVIVAL_DN","description":"Genes whose expression most strongly and consistently associated with the short term survival of patients with high grade glioma tumors."} {"geneset":"MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP","description":"Up-regulated genes predicting poor survival of patients with thyroid carcinoma."} {"geneset":"MONTERO_THYROID_CANCER_POOR_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MONTERO_THYROID_CANCER_POOR_SURVIVAL_DN","description":"Down-regulated genes predicting poor survival of patients with thyroid carcinoma."} {"geneset":"YAGI_AML_WITH_T_8_21_TRANSLOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGI_AML_WITH_T_8_21_TRANSLOCATION","description":"Genes specifically expressed in samples from patients with pediatric AML (acute myeloid leukemia ) bearing t(8;21) translocation."} {"geneset":"YAGI_AML_WITH_INV_16_TRANSLOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGI_AML_WITH_INV_16_TRANSLOCATION","description":"Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing inv(16) translocation."} {"geneset":"YAGI_AML_WITH_T_9_11_TRANSLOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGI_AML_WITH_T_9_11_TRANSLOCATION","description":"Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing t(9;11) translocation."} {"geneset":"YAGI_AML_WITH_11Q23_REARRANGED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAGI_AML_WITH_11Q23_REARRANGED","description":"Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing 11q23 rearrangements."} {"geneset":"MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) and trimethylation mark at K27 (H3K27me3) in neural precursor cells (NPC)."} {"geneset":"MEISSNER_BRAIN_HCP_WITH_H3K4ME2_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_BRAIN_HCP_WITH_H3K4ME2_AND_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing bivalent histone H3 dimethylation mark at K4 (H3K4me2) and trimethlation mark at K27 (H3K27me3) in brain."} {"geneset":"YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) samples from patients with early recurrence (within 2 years after surgery) after resection."} {"geneset":"YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) samples from patients with early recurrence (within 2 years after surgery) after resection."} {"geneset":"MEISSNER_NPC_HCP_WITH_H3K4ME2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_NPC_HCP_WITH_H3K4ME2","description":"Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) in neural precursor cells (NPC)."} {"geneset":"MEISSNER_BRAIN_HCP_WITH_H3K4ME2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEISSNER_BRAIN_HCP_WITH_H3K4ME2","description":"Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark (H3K4me2) in brain."} {"geneset":"MIKKELSEN_MCV6_HCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MCV6_HCP_WITH_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state)."} {"geneset":"MIKKELSEN_MCV6_ICP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MCV6_ICP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing the bivalent trimethylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state)."} {"geneset":"MIKKELSEN_MCV6_ICP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MCV6_ICP_WITH_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state)."} {"geneset":"MIKKELSEN_MCV6_LCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MCV6_LCP_WITH_H3K27ME3","description":"Genes with low-CpG-density promoters (LCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state)."} {"geneset":"MIKKELSEN_MCV6_LCP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MCV6_LCP_WITH_H3K4ME3","description":"Genes with low-CpG-density promoters (LCP) bearing the tri-methylation mark at H3K4 (H3K4me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state)."} {"geneset":"MIKKELSEN_MEF_ICP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MEF_ICP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing the bivalent tri-methylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MEF cells (embryonic fibroblasts)."} {"geneset":"MIKKELSEN_MEF_ICP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MEF_ICP_WITH_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MEF cells (embryonic fibroblasts)."} {"geneset":"MIKKELSEN_MEF_LCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MEF_LCP_WITH_H3K27ME3","description":"Genes with low-CpG-density promoters (LCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MEF cells (embryonic fibroblasts)."} {"geneset":"MIKKELSEN_MEF_LCP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MEF_LCP_WITH_H3K4ME3","description":"Genes with low-CpG-density promoters (LCP) bearing tri-methylation mark at H3K4 (H3K4me3) in MEF cells (embryonic fibroblasts)."} {"geneset":"MIKKELSEN_IPS_WITH_HCP_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_IPS_WITH_HCP_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV8.1 (induced pluripotent cells, iPS)."} {"geneset":"MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED","description":"Genes with high-CpG-density promoters (HCP) without H3 methylation marks at either H3K4 or H3K27 in MCV8.1 cells (induced pluripotent cells, iPS)."} {"geneset":"MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing the bivalent tri-methylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MCV8.1 cells (induced pluripotent cells, iPS)."} {"geneset":"MIKKELSEN_IPS_ICP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_IPS_ICP_WITH_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV8.1 cells (induced pluripotent cells, iPS)."} {"geneset":"MIKKELSEN_IPS_LCP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_IPS_LCP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with low-CpG-density promoters (LCP) bearing the bivalent tri-methylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MCV8.1 cells (induced pluripotent cells, iPS)."} {"geneset":"MIKKELSEN_IPS_LCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_IPS_LCP_WITH_H3K27ME3","description":"Genes with low-CpG-density promoters (LCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV8.1 cells (induced pluripotent cells, iPS)."} {"geneset":"MIKKELSEN_IPS_LCP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_IPS_LCP_WITH_H3K4ME3","description":"Table 2S. Genes in MEF, MCV6, MCV8.1 and ES cells by epigenetic mark of their promoter"} {"geneset":"GLINSKY_CANCER_DEATH_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GLINSKY_CANCER_DEATH_UP","description":"Genes whose over-expression is associated with the risk of death in multiple cancer types"} {"geneset":"KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP","description":"Genes up-regulated in hepatocellular carcinoma (HCC) with early recurrence."} {"geneset":"KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_DN","description":"Genes down-regulated in hepatocellular carcinoma (HCC) with early recurrence."} {"geneset":"OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_UP","description":"Genes up-regulated in both the patients in the multicentric hepatocellular carcinoma (HCC) group and those with multicentric recurrence."} {"geneset":"OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_DN","description":"Genes down-regulated in both the patients in the multicentric hepatocellular carcinoma (HCC) group and those with multicentric recurrence."} {"geneset":"MARSON_FOXP3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSON_FOXP3_TARGETS_UP","description":"Genes up-regulated by FOXP3 [GeneID=50943] in both ex vivo and hybridoma cells."} {"geneset":"MARSON_FOXP3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARSON_FOXP3_TARGETS_DN","description":"Genes down-regulated by FOXP3 [GeneID=50943] in both ex vivo and hybridoma cells."} {"geneset":"ONO_AML1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONO_AML1_TARGETS_UP","description":"Genes up-regulated in CD4+ [GeneID=920] T lymphocytes by expression of AML1 [GeneID=861] off a viral vector."} {"geneset":"ONO_AML1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONO_AML1_TARGETS_DN","description":"Genes down-regulated in CD4+ [GeneID=920] T lymphocytes by expression of AML1 [GeneID=861] off a viral vector."} {"geneset":"ONO_FOXP3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONO_FOXP3_TARGETS_UP","description":"Genes up-regulated in CD4+ [GeneID=920] T lymphocytes transduced with FOXP3 [GeneID=50943]."} {"geneset":"ONO_FOXP3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONO_FOXP3_TARGETS_DN","description":"Genes down-regulated in CD4+ [GeneID=920] T lymphocytes transduced with FOXP3 [GeneID=50943]."} {"geneset":"SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_UP","description":"Genes up-regulated in prostate cancer samples bearing the fusion of TMPRSS2 with ERG [GeneID=7113;2078]."} {"geneset":"SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_DN","description":"Genes down-regulated in prostate cancer samples bearing the fusion of TMPRSS2 with ERG [GeneID=7113;2078]."} {"geneset":"SCHOEN_NFKB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHOEN_NFKB_SIGNALING","description":"Genes down-regulated in A375 cells (melanoma) treated with KINK-1, a small molecule inhibitor of NFKB."} {"geneset":"NAKAYAMA_FGF2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAYAMA_FGF2_TARGETS","description":"Genes down-regulated in S-17 cells (bone marrow stroma) after stimulation with FGF2 [GeneID=2247]."} {"geneset":"NGO_MALIGNANT_GLIOMA_1P_LOH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NGO_MALIGNANT_GLIOMA_1P_LOH","description":"Proteins with reduced expression in mulignant glioma cell line (A172) which bears loss of heterozygosity (LOH) in the 1p region."} {"geneset":"YANAGISAWA_LUNG_CANCER_RECURRENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANAGISAWA_LUNG_CANCER_RECURRENCE","description":"Genes defining a 25-signal proteomic signature associated with a high risk of cancer recurrence and poor survival of NSCLC (non-small cell lung cancer) patients."} {"geneset":"KESHELAVA_MULTIPLE_DRUG_RESISTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KESHELAVA_MULTIPLE_DRUG_RESISTANCE","description":"Genes up-regulated in multiple drug resistant neuroblastoma cell lines."} {"geneset":"SEIKE_LUNG_CANCER_POOR_SURVIVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEIKE_LUNG_CANCER_POOR_SURVIVAL","description":"The 'CLASS-11' set of pro- and anti-inflammatory cytokines whose expression identifies stage I lung adenocarcinoma patients with poor prognosis."} {"geneset":"WINNEPENNINCKX_MELANOMA_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WINNEPENNINCKX_MELANOMA_METASTASIS_DN","description":"Genes from the 254-gene classifier which were down-regulated in melanoma patients with a reported distant metastasis within 4 years."} {"geneset":"TSAI_DNAJB4_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSAI_DNAJB4_TARGETS_UP","description":"Genes up-regulated in CL1-5 cells (lung cancer) overexpressing DNAJB4 [GeneID=11080] off a plasmid vector."} {"geneset":"TSAI_DNAJB4_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSAI_DNAJB4_TARGETS_DN","description":"Genes down-regulated in CL1-5 cells (lung cancer) overexpressing DNAJB4 [GeneID=11080] off a plasmid vector."} {"geneset":"ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN","description":"Down-regulated genes associated with poor survival prognosis of patients with metastatic neuroblastoma that lack MYCN [GeneID=4613] amplification."} {"geneset":"LI_PROSTATE_CANCER_EPIGENETIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_PROSTATE_CANCER_EPIGENETIC","description":"Genes affected by epigenetic aberrations in prostate cancer."} {"geneset":"UROSEVIC_RESPONSE_TO_IMIQUIMOD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/UROSEVIC_RESPONSE_TO_IMIQUIMOD","description":"Interferon cluster genes up-regulated in skin tumors treated with imiquimod [PubChem=57469]."} {"geneset":"KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS","description":"Inflammatory cytokines and their receptors modulated in brain tumors after treatment with an oncocytic virus, a potential anticancer therapy."} {"geneset":"KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS_AND_CYCLIC_RGD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS_AND_CYCLIC_RGD","description":"Inflammatory cytokines and their receptors moduated in brain tumors in response to treatment with cyclic RGD peptide prior to the oncocytic virus therapy."} {"geneset":"FONTAINE_FOLLICULAR_THYROID_ADENOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FONTAINE_FOLLICULAR_THYROID_ADENOMA_UP","description":"Genes up-regulated in follicular thyroid adenoma (FTA) compared to other thyroid tumors."} {"geneset":"FONTAINE_FOLLICULAR_THYROID_ADENOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FONTAINE_FOLLICULAR_THYROID_ADENOMA_DN","description":"Genes down-regulated in follicular thyroid adenoma (FTA) compared to other thyroid tumors."} {"geneset":"FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_UP","description":"Genes up-regulated in thyroid tumors of uncertain malignancy (T-UM) compared to other thyroid tumors."} {"geneset":"FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN","description":"Genes down-regulated in thyroid tumors of uncertain malignancy (T-UM) compared to other thyroid tumors."} {"geneset":"FONTAINE_PAPILLARY_THYROID_CARCINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FONTAINE_PAPILLARY_THYROID_CARCINOMA_UP","description":"Genes up-regulated in papillary thyroid carcinoma (PTC) compared to other thyroid tumors."} {"geneset":"FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN","description":"Genes down-regulated in papillary thyroid carcinoma (PTC) compared to other thyroid tumors."} {"geneset":"LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL","description":"Genes changed in LSK cells (bone marrow) as a function of a QTL for the size of hematopoietic stem cell (HSC) population: comparison of reciprocal congenic strains D.B. Chr3 (DB), B.D. Chr3 (BD) and the parental strains B6 and D2."} {"geneset":"WEBER_METHYLATED_LCP_IN_FIBROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_LCP_IN_FIBROBLAST_UP","description":"Methylated germline-specific genes with low-CpG-density promoters (LCP) in primary fibroblasts."} {"geneset":"WEBER_METHYLATED_LCP_IN_FIBROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_LCP_IN_FIBROBLAST_DN","description":"Unmethylated germline-specific genes with low-CpG-density promoters (LCP) in primary fibroblasts."} {"geneset":"WEBER_METHYLATED_ICP_IN_FIBROBLAST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_ICP_IN_FIBROBLAST","description":"Germline-specific genes with intermediate-CpG-density promoters (ICP) that are methylated in primary fibroblasts."} {"geneset":"WEBER_METHYLATED_ICP_IN_SPERM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_ICP_IN_SPERM_UP","description":"Methylated germline-specific genes with intermediate-CpG-density promoters (ICP) in sperm."} {"geneset":"WEBER_METHYLATED_ICP_IN_SPERM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_ICP_IN_SPERM_DN","description":"Unmethylated germline-specific genes with intermediate-CpG-density promoters (ICP) in sperm."} {"geneset":"WEBER_METHYLATED_LCP_IN_SPERM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_LCP_IN_SPERM_UP","description":"Methylated germline-specific genes with low-CpG-density promoters (LCP) in sperm."} {"geneset":"WEBER_METHYLATED_LCP_IN_SPERM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WEBER_METHYLATED_LCP_IN_SPERM_DN","description":"Unmethylated germline-specific genes with low-CpG-density promoters (LCP) in sperm."} {"geneset":"PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP","description":"The XPRSS-Int network genes up-regulated in breast tumors from patients with germline mutations in BRCA1 [GeneID=672] compared to those with the wild type allele."} {"geneset":"PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_DN","description":"The XPRSS-Int network genes down-regulated in breast tumors from patients with germline mutations in BRCA1 [GeneID=672] compared to those with the wild type allele."} {"geneset":"GYORFFY_DOXORUBICIN_RESISTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GYORFFY_DOXORUBICIN_RESISTANCE","description":"Genes associated with resistance to doxorubicin [PubChem=31703]."} {"geneset":"GYORFFY_MITOXANTRONE_RESISTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GYORFFY_MITOXANTRONE_RESISTANCE","description":"Genes associated with resistance to mitoxantrone [PubChem=4212]."} {"geneset":"SYED_ESTRADIOL_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SYED_ESTRADIOL_RESPONSE","description":"Genes responsive to estradiol [PubChem=5757] both in normal and cancer ovarian cell lines."} {"geneset":"WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_UP","description":"Selected genes with immunologic function which were reciprocally changed in evasion and tolerogenic tumor models."} {"geneset":"WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_DN","description":"Selected genes with immunologic function which were reciprocally changed in evasion and tolerogenic tumor models."} {"geneset":"STEIN_ESR1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEIN_ESR1_TARGETS","description":"Genes regulated by ESR1 [GeneID=2099] in MCF-7 cells (breast cancer)."} {"geneset":"STEIN_ESRRA_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEIN_ESRRA_TARGETS","description":"Genes regulated by ESRRA [GeneID=2101] in MCF-7 cells (breast cancer)."} {"geneset":"STEIN_ESTROGEN_RESPONSE_NOT_VIA_ESRRA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEIN_ESTROGEN_RESPONSE_NOT_VIA_ESRRA","description":"Genes up-regulated by estradiol [PubChem=5757] and not modulated by ESRRA [GeneID=2101] in MCF-7 cells (breast cancer)."} {"geneset":"SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP","description":"Selected genes up-regulated in peripheral blood monocytes (PBMC) of patients with hepatocellular carcinoma (HCC) compared to those with chronic hepatitis."} {"geneset":"LOPEZ_EPITHELIOID_MESOTHELIOMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_EPITHELIOID_MESOTHELIOMA","description":"Top 20 genes expressed higher in epithelioid than in sarcomatoid mesothelioma samples."} {"geneset":"LOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL_UP","description":"Top genes associated with favorable overall survival of mesothelioma patients after surgery."} {"geneset":"LOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL_DN","description":"Top genes associated with unfavorable overall survival of mesothelioma patients after surgery."} {"geneset":"LOPEZ_MESOTHELIOMA_SURVIVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MESOTHELIOMA_SURVIVAL_UP","description":"Top genes associated with favorable survival after surgery of patients with epithelioid mesothelioma."} {"geneset":"LOPEZ_MESOTHELIOMA_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_MESOTHELIOMA_SURVIVAL_DN","description":"Top genes associated with unfavorable survival after surgery of patients with epithelioid mesothelioma."} {"geneset":"KORKOLA_CORRELATED_WITH_POU5F1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_CORRELATED_WITH_POU5F1","description":"Genes whose expression pattern in adult male germ cell tumors (GCT) correlates with POU5F1 [GeneID=5460]."} {"geneset":"KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_UP","description":"Top 25 most highly expressed genes in embryonic carcinoma relative to seminoma tumors."} {"geneset":"KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_DN","description":"Top 25 most highly expressed genes in seminoma relative to embryonic carcinoma tumors."} {"geneset":"KOBAYASHI_EGFR_SIGNALING_24HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOBAYASHI_EGFR_SIGNALING_24HR_UP","description":"Genes up-regulated in H1975 cells (non-small cell lung cancer, NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h."} {"geneset":"KOBAYASHI_EGFR_SIGNALING_24HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOBAYASHI_EGFR_SIGNALING_24HR_DN","description":"Genes down-regulated in H1975 cells (non-small cell lung cancer, NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h."} {"geneset":"FOURNIER_ACINAR_DEVELOPMENT_LATE_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOURNIER_ACINAR_DEVELOPMENT_LATE_2","description":"Genes identified by method 2 as coordinately down-regulated late in HMEC cells (mammary epithelium) during acinar development in vitro."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_PCA1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_PCA1_UP","description":"Top up-regulated genes from principal component 1 (PCA1) which captures variation between normal plasma cells and tumors arising from aberrant expression of BCL2L1 and MYC [GeneID=598;4609]."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_PCA1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_PCA1_DN","description":"Top down-regulated genes from principal component 1 (PCA1) which captures variation between normal plasma cells and tumors arising from aberrant expression of BCL2L1 and MYC [GeneID=598;4609]."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_PCA3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_PCA3_UP","description":"Top up-regulated genes from principal component 3 (PCA3) which captures variation among different plasma cell tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609]."} {"geneset":"BOYLAN_MULTIPLE_MYELOMA_PCA3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOYLAN_MULTIPLE_MYELOMA_PCA3_DN","description":"Top down-regulated genes from principal component 3 (PCA3) which captures variation among different plasma cell tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609]."} {"geneset":"HOSHIDA_LIVER_CANCER_SUBCLASS_S1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOSHIDA_LIVER_CANCER_SUBCLASS_S1","description":"Genes from 'subtype S1' signature of hepatocellular carcinoma (HCC): aberrant activation of the WNT signaling pathway."} {"geneset":"HOSHIDA_LIVER_CANCER_SUBCLASS_S2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOSHIDA_LIVER_CANCER_SUBCLASS_S2","description":"Genes from 'subtype S2' signature of hepatocellular carcinoma (HCC): proliferation, MYC and AKT1 [GeneID=4609;207] activation."} {"geneset":"HOSHIDA_LIVER_CANCER_SUBCLASS_S3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOSHIDA_LIVER_CANCER_SUBCLASS_S3","description":"Genes from 'subtype S3' signature of hepatocellular carcinoma (HCC): hepatocyte differentiation."} {"geneset":"PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP","description":"Up-regulated genes in head and neck cancer compared to cervical carcinoma samples."} {"geneset":"PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_DN","description":"Down-regulated genes in head and neck cancer compared to cervical carcinoma samples."} {"geneset":"CAIRO_HEPATOBLASTOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_HEPATOBLASTOMA_UP","description":"Genes up-regulated in hepatoblastoma samples compared to normal liver tissue."} {"geneset":"CAIRO_HEPATOBLASTOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_HEPATOBLASTOMA_DN","description":"Genes down-regulated in hepatoblastoma samples compared to normal liver tissue."} {"geneset":"CAIRO_HEPATOBLASTOMA_CLASSES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_HEPATOBLASTOMA_CLASSES_UP","description":"Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1)."} {"geneset":"CAIRO_HEPATOBLASTOMA_CLASSES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_HEPATOBLASTOMA_CLASSES_DN","description":"Genes down-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1)."} {"geneset":"CAIRO_LIVER_DEVELOPMENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_LIVER_DEVELOPMENT_UP","description":"Genes up-regulated at early fetal liver stage (embryonic days E11.5 - E12.5) compared to the late fetal liver stage (embryonic days E14.5 - E16.5)."} {"geneset":"CAIRO_LIVER_DEVELOPMENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_LIVER_DEVELOPMENT_DN","description":"Genes down-regulated at early fetal liver stage (embryonic days E11.5 - E12.5) compared to the late fetal liver stage (embryonic days E14.5 - E16.5)."} {"geneset":"CAIRO_HEPATOBLASTOMA_POOR_SURVIVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAIRO_HEPATOBLASTOMA_POOR_SURVIVAL","description":"Genes whose expression classifies hepatoblastoma tumors as belonging to either rC1 or rC2 subtypes and whose expression predicts poor survival."} {"geneset":"GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP","description":"Genes exclusively up-regulated in B lymphocytes from CLL (chronic lymphocytic leukemia) patients but with a similiar expression pattern in the normal cells and in the cells from WM (Waldenstroem's macroblobulinemia) patients."} {"geneset":"GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN","description":"Genes exclusively down-regulated in B lymphocytes from CLL (chronic lymphocytic leukemia) patients but with a similiar expression pattern in the normal cells and in the cells from WM (Waldenstroem's macroblobulinemia) patients."} {"geneset":"GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_UP","description":"Genes exclusively up-regulated in B lymphocytes from WM (Waldenstroem's macroblobulinemia) patients but with a similiar expression pattern in the normal cells and in the cells from CLL (chronic lymphocytic leukemia) patients."} {"geneset":"GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN","description":"Genes exclusively down-regulated in B lymphocytes from WM (Waldenstroem's macroblobulinemia) patients but with a similiar expression pattern in the normal cells and in the cells from CLL (chronic lymphocytic leukemia) patients."} {"geneset":"GUTIERREZ_MULTIPLE_MYELOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUTIERREZ_MULTIPLE_MYELOMA_UP","description":"Genes exclusively up-regulated in plasma cells from MM (multiple myeloma) patients but with a similiar expression pattern in the normal cells and in the cells from WM (Waldenstroem's macroblobulinemia) patients."} {"geneset":"GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_2","description":"Genes exclusively up-regulated in B lymphocytes from WM (Waldenstroem's macroglobulinemia) but with a similar expression profile in MM (macroglobulinemia) and normal cells."} {"geneset":"WINNEPENNINCKX_MELANOMA_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WINNEPENNINCKX_MELANOMA_METASTASIS_UP","description":"Genes from the 254-gene classifier which were up-regulated in melanoma patients with a reported distant metastasis within 4 years."} {"geneset":"HAHTOLA_CTCL_CUTANEOUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_CTCL_CUTANEOUS","description":"Genes showing similar expression profiles in all subtypes of cutaneous T cell lymphoma (CTCL)."} {"geneset":"HAHTOLA_CTCL_PATHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAHTOLA_CTCL_PATHOGENESIS","description":"Differentially expressed genes relevant to pathogenesis of cutaneous T cell lymphoma (CTCL)."} {"geneset":"UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN","description":"Genes up-regulated in HUVEC cells (primary endothelium) after stimulation with leukotriene LTD4 [PubChem=3908] or thrombin (F2) [GeneID=2147] for 1 h."} {"geneset":"VANTVEER_BREAST_CANCER_POOR_PROGNOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANTVEER_BREAST_CANCER_POOR_PROGNOSIS","description":"The optimal set of 70 prognostic markers predicting poor breast cancer clinical outcome (defined as developing metastases with 5 years)."} {"geneset":"KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP","description":"Genes up-regulated similarly in primary fibroblast cultures from Werner syndrom patients and normal old donors compared to those from normal young donors."} {"geneset":"KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN","description":"Genes down-regulated similarly in primary fibroblast cultures from Werner syndrom patients and normal old donors compared to those from normal young donors."} {"geneset":"KYNG_NORMAL_AGING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_NORMAL_AGING_UP","description":"Genes distinctly up-regulated in primary fibroblast cultures from normal old donors compared to those from normal young donors."} {"geneset":"KYNG_NORMAL_AGING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_NORMAL_AGING_DN","description":"Genes distinctly down-regulated in primary fibroblast cultures from normal old donors compared to those from normal young donors."} {"geneset":"KYNG_WERNER_SYNDROM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_WERNER_SYNDROM_UP","description":"Genes distinctly up-regulated in primary fibroblast cultures from Werner syndrom patients compared to those from normal young donors."} {"geneset":"KYNG_WERNER_SYNDROM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_WERNER_SYNDROM_DN","description":"Genes distinctly down-regulated in primary fibroblast cultures from Werner syndrom patients compared to those from normal young donors."} {"geneset":"CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY","description":"Genes down-regulated in T cell acute lymphocytic leukemia (T-ALL) patients refractory to chemotherapy treatment."} {"geneset":"CHIARETTI_T_ALL_RELAPSE_PROGNOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHIARETTI_T_ALL_RELAPSE_PROGNOSIS","description":"Genes whose expression predicted relapse in less than 2 years after chemotherapy for adult patients with T-ALL (T cell lymphoblastic leukemia)."} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_IL3RA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_IL3RA","description":"Genes whose expression is coregulated with that of IL3RA [GeneID=3563] in hematopoietic stem cells (HSC)."} {"geneset":"BYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS","description":"Genes trans-regulated by the hematopoietic stem cell (HSC) proliferation QTL (quantitative trait locus) Scp2."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_CD1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_CD1_DN","description":"Top 50 down-regulated genes in cluster CD-1 of multiple myeloma samples with the characteristic expression spike of CCND1 [GeneID=595]."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_CD2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_CD2_DN","description":"Top 50 down-regulated genes in cluster CD-2 of multiple myeloma samples with the charachteristic expression spike of CCND3 [GeneID=896]."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_LB_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_LB_DN","description":"Top 50 down-regulated genes in cluster LB of multiple myeloma samples belonging to the low bone disease group."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_HP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_HP_DN","description":"Top 50 down-regulated genes in cluster HP of multiple myeloma samples characterized by a hyperploid signature."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_MF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_MF_DN","description":"Top 50 down-regulated genes in cluster MF of multiple myeloma samples with characteristic expression spike of MAF family transcription factors."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_MS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_MS_DN","description":"Top 50 down-regulated genes in cluster MS of multiple myeloma samples with characteristic expression spike of WHSC1 [GeneID=7468]."} {"geneset":"ZHAN_MULTIPLE_MYELOMA_PR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHAN_MULTIPLE_MYELOMA_PR_DN","description":"Top 50 down-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes."} {"geneset":"DANG_REGULATED_BY_MYC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DANG_REGULATED_BY_MYC_UP","description":"Genes up-regulated by MYC [GeneID=4609], according to the MYC Target Gene Database."} {"geneset":"DANG_REGULATED_BY_MYC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DANG_REGULATED_BY_MYC_DN","description":"Genes down-regulated by MYC [GeneID=4609], according to the MYC Target Gene Database."} {"geneset":"DANG_MYC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DANG_MYC_TARGETS_UP","description":"Genes up-regulated by MYC [GeneID=4609] and whose promoters are bound by MYC, according to MYC Target Gene Database."} {"geneset":"DANG_MYC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DANG_MYC_TARGETS_DN","description":"Genes down-regulated by MYC [GeneID=4609] and whose promoters are bound by MYC, according to MYC Target Gene Database."} {"geneset":"DANG_BOUND_BY_MYC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DANG_BOUND_BY_MYC","description":"Genes whose promoters are bound by MYC [GeneID=4609], according to MYC Target Gene Database."} {"geneset":"DORN_ADENOVIRUS_INFECTION_12HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORN_ADENOVIRUS_INFECTION_12HR_UP","description":"Genes up-regulated in HeLa cells (cervical carcinoma) 12 h after infection with adenovirus Ad12."} {"geneset":"DORN_ADENOVIRUS_INFECTION_12HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORN_ADENOVIRUS_INFECTION_12HR_DN","description":"Genes down-regulated in HeLa cells (cervical carcinoma) 12 h after infection with adenovirus Ad12."} {"geneset":"DORN_ADENOVIRUS_INFECTION_24HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORN_ADENOVIRUS_INFECTION_24HR_UP","description":"Genes up-regulated in HeLa cells (cervical carcinoma) 24 h after infection with adenovirus Ad12."} {"geneset":"DORN_ADENOVIRUS_INFECTION_24HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORN_ADENOVIRUS_INFECTION_24HR_DN","description":"Genes down-regulated in HeLa cells (cervical carcinoma) 24 h after infection with adenovirus Ad12."} {"geneset":"DORN_ADENOVIRUS_INFECTION_32HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORN_ADENOVIRUS_INFECTION_32HR_UP","description":"Genes up-regulated in HeLa cells (cervical carcinoma) 32 h after infection with adenovirus Ad12."} {"geneset":"DORN_ADENOVIRUS_INFECTION_32HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORN_ADENOVIRUS_INFECTION_32HR_DN","description":"Genes down-regulated in HeLa cells (cervical carcinoma) 32 h after infection with adenovirus Ad12."} {"geneset":"DORN_ADENOVIRUS_INFECTION_48HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORN_ADENOVIRUS_INFECTION_48HR_UP","description":"Genes up-regulated in HeLa cells (cervical carcinoma) 48 h after infection with adenovirus Ad12."} {"geneset":"DORN_ADENOVIRUS_INFECTION_48HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORN_ADENOVIRUS_INFECTION_48HR_DN","description":"Genes down-regulated in HeLa cells (cervical carcinoma) 48 h after infection with adenovirus Ad12."} {"geneset":"TIAN_TNF_SIGNALING_VIA_NFKB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIAN_TNF_SIGNALING_VIA_NFKB","description":"Genes modulated in HeLa cells (cervical carcinoma) by TNF [GeneID=7124] via NFKB pathway."} {"geneset":"TIAN_TNF_SIGNALING_NOT_VIA_NFKB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIAN_TNF_SIGNALING_NOT_VIA_NFKB","description":"Genes modulated in HeLa cells (cervical carcinoma) by TNF [GeneID=7124] not via NFKB pathway."} {"geneset":"WONG_EMBRYONIC_STEM_CELL_CORE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_EMBRYONIC_STEM_CELL_CORE","description":"The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module."} {"geneset":"WONG_ADULT_TISSUE_STEM_MODULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WONG_ADULT_TISSUE_STEM_MODULE","description":"The 'adult tissue stem' module: genes coordinately up-regulated in a compendium of adult tissue stem cells."} {"geneset":"NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP","description":"Top 100 probe sets contrubuting to the positive side of the 1st principal component; predominantly associated with spindle cell and pleomorphic sarcoma samples."} {"geneset":"NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN","description":"Top 100 probe sets contrubuting to the negative side of the 1st principal component; predominantly associated with synovial sarcoma and myxoid/round cell liposarcoma samples."} {"geneset":"NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP","description":"Top 100 probe sets contrubuting to the positive side of the 2nd principal component; associated with adipocytic differentiation."} {"geneset":"NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN","description":"Top 100 probe sets contrubuting to the negative side of the 2nd principal component; associated with adipocytic differentiation."} {"geneset":"CHANDRAN_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANDRAN_METASTASIS_UP","description":"Genes up-regulated in metastatic tumors from the whole panel of patients with prostate cancer."} {"geneset":"CHANDRAN_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANDRAN_METASTASIS_DN","description":"Genes down-regulated in metastatic tumors from the whole panel of patients with prostate cancer."} {"geneset":"MIKKELSEN_ES_HCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_ES_HCP_WITH_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing histone H3 K27 trimethylation mark (H327me3) in embryonic stem cells (ES)."} {"geneset":"MIKKELSEN_ES_HCP_WITH_H3_UNMETHYLATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_ES_HCP_WITH_H3_UNMETHYLATED","description":"Genes with high-CpG-density promoters (HCP) without H3 methylation marks at K4 and K27 in embryonic stem cells (ES)."} {"geneset":"MIKKELSEN_ES_ICP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_ES_ICP_WITH_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 K27 trimethylation mark (H3K27me3) in embryonic stem cells (ES)."} {"geneset":"MIKKELSEN_ES_ICP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_ES_ICP_WITH_H3K4ME3","description":"Genes with intermediate-CpG-density (ICP) promoters bearing histone H3 K4 trimethylation mark (H3K4me3) in embryonic stem cells (ES)."} {"geneset":"MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing bivalent histone H3 methylation mark (H3K4me3 and H3K27me3) in embryonic stem cells (ES)."} {"geneset":"MIKKELSEN_ES_LCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_ES_LCP_WITH_H3K27ME3","description":"Genes with low-CpG-density promoters bearing H3 trimethylation mark at K27 (H3K27me3) in embryonic stem cells (ES)."} {"geneset":"MIKKELSEN_ES_LCP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_ES_LCP_WITH_H3K4ME3","description":"Genes with low-CpG-density promoters (LCP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in embryonic stem cells (ES)."} {"geneset":"MIKKELSEN_ES_LCP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_ES_LCP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with low-CpG-density promoters (LCP) bearing the bivalent histone H3 trimethylation mark at K4 and K27 (H3K4me3 and H3K27me3) in embryonic stem cells (ES)."} {"geneset":"MIKKELSEN_NPC_HCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_NPC_HCP_WITH_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in neural progenitor cells (NPC)."} {"geneset":"MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing the bivalent histone H3 trimethylation mark at K4 and K27 (H3K4me3 and H3K27me3) in neural progenitor cells (NPC)."} {"geneset":"MIKKELSEN_NPC_ICP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_NPC_ICP_WITH_H3K27ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in neural progenitor cells (NPC)."} {"geneset":"MIKKELSEN_NPC_ICP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_NPC_ICP_WITH_H3K4ME3","description":"Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC)."} {"geneset":"MIKKELSEN_NPC_WITH_LCP_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_NPC_WITH_LCP_H3K27ME3","description":"Genes with low-CpG-density promoters (LCP) bearing histone H3 trimethylation mark at K27 in neural progenitor cells (NPC)."} {"geneset":"MIKKELSEN_NPC_LCP_WITH_H3K4ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_NPC_LCP_WITH_H3K4ME3","description":"Genes with low-CpG-density promoters (LCP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC)."} {"geneset":"MIKKELSEN_MEF_HCP_WITH_H3K27ME3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MEF_HCP_WITH_H3K27ME3","description":"Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in MEF cells (embryonic fibroblast)."} {"geneset":"MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED","description":"Genes with high-CpG-density promoters (HCP) with unmethylated histone H3 in MEF cells (embryonic fibroblast)."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 0."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 1."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_2","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 2."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_3","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 3."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_4","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 4."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 5."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 6."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 7."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 8."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 9."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_10","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 10."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 11."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 12."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 13."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 14."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_15","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 15."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 16."} {"geneset":"YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17","description":"Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 17."} {"geneset":"SENGUPTA_EBNA1_ANTICORRELATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SENGUPTA_EBNA1_ANTICORRELATED","description":"Genes whose reduced expression in nasopharyngeal carinoma (NPC) correlated most with the increased expression of EBNA1 [GeneID=3783774], a latent gene of Epstein-Barr virus (EBV)."} {"geneset":"YIH_RESPONSE_TO_ARSENITE_C5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YIH_RESPONSE_TO_ARSENITE_C5","description":"Genes in cluster 5: slowly down-regulated in HFW cells (fibroblast) by sodium arsenite [PubChem=26435]."} {"geneset":"MOOTHA_PYR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_PYR","description":"Genes involved in pyruvate metabolism; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets."} {"geneset":"MOOTHA_FFA_OXYDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_FFA_OXYDATION","description":"Genes involved in free fatty acid oxidation; based on literature and sequence annotation resources and coverted to Affymetrix HG-U133A probe sets."} {"geneset":"MOOTHA_GLUCONEOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_GLUCONEOGENESIS","description":"Genes involved in gluconeogenesis; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets."} {"geneset":"MOOTHA_GLYCOGEN_METABOLISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_GLYCOGEN_METABOLISM","description":"Genes involved in glycogen metabolism; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets."} {"geneset":"MOOTHA_GLYCOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MOOTHA_GLYCOLYSIS","description":"Genes involved in glycolysis; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets."} {"geneset":"LY_AGING_OLD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LY_AGING_OLD_UP","description":"Genes up-regulated in fibroblasts from old individuals, compared to those from young donors."} {"geneset":"NAKAMURA_ADIPOGENESIS_EARLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_ADIPOGENESIS_EARLY_UP","description":"Genes up-regulated in mesenchymal stem cells during early phase of adipogenesis, defined as days 1 to 5 of culturing with adipogenic hormones."} {"geneset":"NAKAMURA_ADIPOGENESIS_EARLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_ADIPOGENESIS_EARLY_DN","description":"Genes down-regulated in mesenchymal stem cells during early phase of adipogenesis, defined as days 1 to 5 of culturing with adipogenic hormones."} {"geneset":"NAKAMURA_ADIPOGENESIS_LATE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_ADIPOGENESIS_LATE_UP","description":"Genes up-regulated in mesenchymal stem cells during late phase of adipogenesis, defined as days 7 to 14 of culturing with adipogenic hormones."} {"geneset":"NAKAMURA_ADIPOGENESIS_LATE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NAKAMURA_ADIPOGENESIS_LATE_DN","description":"Genes down-regulated in mesenchymal stem cells during late phase of adipogenesis, defined as days 7 to 14 of culturing with adipogenic hormones."} {"geneset":"RAMPON_ENRICHED_LEARNING_ENVIRONMENT_EARLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAMPON_ENRICHED_LEARNING_ENVIRONMENT_EARLY_DN","description":"Genes down-regulated in the brain cortex of mice that were exposed to an enriched learning environment for one day."} {"geneset":"VERRECCHIA_RESPONSE_TO_TGFB1_C6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERRECCHIA_RESPONSE_TO_TGFB1_C6","description":"Cluster 6: ECM related genes up-regulated in dermal fibroblasts later than 30 min after TGFB1 [GeneID=7040] addition; slowly increased up to 120 min time point, then reached a plateau."} {"geneset":"TRACEY_RESISTANCE_TO_IFNA2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TRACEY_RESISTANCE_TO_IFNA2_UP","description":"Genes up-regulated in huT78R cells (cutaneous T-cell lymphoma, CTCL) resistant to IFNA2 [GeneID=3440] compared to the IFN2A sensitive parental cell line."} {"geneset":"BAUS_TFF2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAUS_TFF2_TARGETS_UP","description":"Genes up-regulated in pyloric atrium with knockout of TFF2 [GeneID=7032]."} {"geneset":"BAUS_TFF2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAUS_TFF2_TARGETS_DN","description":"Genes down-regulated in pyloric atrium with knockout of TFF2 [GeneID=7032]."} {"geneset":"KAMMINGA_SENESCENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAMMINGA_SENESCENCE","description":"Genes down-regulated on serial passage of MEF cells (embryonic fibroblast)."} {"geneset":"HO_LIVER_CANCER_VASCULAR_INVASION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HO_LIVER_CANCER_VASCULAR_INVASION","description":"Gene expression signature of vascular invasion of hepatocellular carcinoma (HCC)."} {"geneset":"GERHOLD_RESPONSE_TO_TZD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GERHOLD_RESPONSE_TO_TZD_UP","description":"Genes up-regulated in 3T3-L1 cells (fibroblast) induced to differentiate to mature adipocytes and then treated with a TZD derivative AD-5075 [PubChem=128440], a PPARG [GeneID=5468] activator."} {"geneset":"GERHOLD_RESPONSE_TO_TZD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GERHOLD_RESPONSE_TO_TZD_DN","description":"Genes down-regulated in 3T3-L1 cells (fibroblast) induced to differentiate to mature adipocytes and then treated with a TZD derivative AD-5075 [PubChem=128440], a PPARG [GeneID=5468] activator."} {"geneset":"MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_1","description":"Cluster 1: genes up-regulated in SW260 cells (colon cancer) by sodium butyrate, curcumin, sulindac and TSA [PubChem=5222465;969516;5352;5562]."} {"geneset":"MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_2","description":"Cluster 2: genes up-regulated in SW260 cells (colon cancer) by sodium butyrate, curcumin, sulindac and TSA [PubChem=5222465;969516;5352;5562]."} {"geneset":"MURAKAMI_UV_RESPONSE_1HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MURAKAMI_UV_RESPONSE_1HR_UP","description":"Genes up-regulated in primary keratinocytes at 1 h after UVB irradiation."} {"geneset":"MURAKAMI_UV_RESPONSE_1HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MURAKAMI_UV_RESPONSE_1HR_DN","description":"Genes down-regulated in primary keratinocytes at 1 h after UVB irradiation."} {"geneset":"KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_UP","description":"Genes up-regulated in response to hydorgen peroxyde [PubChem=784] in CS-B cells (Cockaine syndrome fibroblast, CS) with defficient ERCC6 [GeneID=2074]."} {"geneset":"KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_DN","description":"Genes down-regulated in response to hydorgen peroxyde [PubChem=784] in CS-B cells (Cockaine syndrome fibroblast, CS) with defficient ERCC6 [GeneID=2074]."} {"geneset":"VISALA_AGING_LYMPHOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VISALA_AGING_LYMPHOCYTE_UP","description":"Genes up-regulated in peripheral lymphocytes from old individuals compared to those from young donors."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_FLUOROURACIL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_FLUOROURACIL","description":"Top genes associated with chemosensitivity to 5-fluorouracil [PubChem=3385] across 85 tumor xenografts."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_CISPLATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_CISPLATIN","description":"Top genes associated with chemosensitivity to cisplatin [PubChem=2767] across 85 tumor xenografts."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_NIMUSTINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_NIMUSTINE","description":"Top genes associated with chemosensitivity to nimustine [PubChem=39214] across 85 tumor xenografts."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_DOXORUBICIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_DOXORUBICIN","description":"Top genes associated with chemosensitivity to doxorubicin [PubChem=31703] across 85 tumor xenografts."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_CYCLOPHOSPHAMIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_CYCLOPHOSPHAMIDE","description":"Top genes associated with chemosensitivity to cyclophosphamide [PubChem=2907] across 85 tumor xenografts."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_MITOMYCIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_MITOMYCIN","description":"Top genes associated with chemosensitivity to mitomycin [PubChem=5746] across 85 tumor xenografts."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_METHOTREXATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_METHOTREXATE","description":"Top genes associated with chemosensitivity to methotrexate [PubChem=4112] across 85 tumor xenografts."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_VINCRISTINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_VINCRISTINE","description":"Top genes associated with chemosensitivity to vincristine [PubChem=5978] across 85 tumor xenografts."} {"geneset":"ZEMBUTSU_SENSITIVITY_TO_VINBLASTINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZEMBUTSU_SENSITIVITY_TO_VINBLASTINE","description":"Top genes associated with chemosensitivity to vinblastine [PubChem=13342] across 85 tumor xenografts."} {"geneset":"DAZARD_UV_RESPONSE_CLUSTER_G5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G5","description":"Cluster G5: genes up-regulated in NHEK cells (normal keratinocyte) at 3 h and 24 h time points after UV-B irradiation."} {"geneset":"DAZARD_UV_RESPONSE_CLUSTER_G24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G24","description":"Cluster G24: genes induced in NHEK (normal keratinocyte) but not in SCC12B2 cells (squamous cell carcinoma) by UV-B radiation."} {"geneset":"DAZARD_UV_RESPONSE_CLUSTER_G28","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G28","description":"Cluster G28: genes differentially up-regulated in NHEK (normal keratinocyte) compared to SCC12B2 cells (squamous cell carcinoma) by UV-B radiation."} {"geneset":"RUAN_RESPONSE_TO_TROGLITAZONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RUAN_RESPONSE_TO_TROGLITAZONE_DN","description":"Adipocyte abundant genes down-regulated in 3T3-L1 cells (fibroblasts induced to differentiate to adipocytes) in response to troglitazone [PubChem=5591]."} {"geneset":"NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_DN","description":"Top 20 genes whose down-regulation correlated with gastrointestinal stromal tumors (GIST) compared to synovial sarcoma."} {"geneset":"NIELSEN_GIST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_GIST","description":"A cluster of genes specifically up-regulated in gastrointestinal stromal tumors (GIST)."} {"geneset":"NIELSEN_LEIOMYOSARCOMA_CNN1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_LEIOMYOSARCOMA_CNN1_DN","description":"Top 20 negative significant genes associated with leiomyosarcoma tumors expressing muscle gene cluster with CNN1 [GeneID=1264]."} {"geneset":"NIELSEN_LEIOMYOSARCOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_LEIOMYOSARCOMA_DN","description":"Top 20 negative significant genes associated with CNN1 [GeneID=1264] negative leiomyosarcoma tumors."} {"geneset":"NIELSEN_SYNOVIAL_SARCOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_SYNOVIAL_SARCOMA_UP","description":"Top 20 positive significant genes associated with synovial sarcoma tumors."} {"geneset":"NIELSEN_SYNOVIAL_SARCOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_SYNOVIAL_SARCOMA_DN","description":"Top 20 negative significant genes associated with synovial sarcoma tumors."} {"geneset":"NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_DN","description":"Top 20 negative significant genes associated with malignant fibrous histiocytoma tumors."} {"geneset":"NIELSEN_SCHWANNOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NIELSEN_SCHWANNOMA_DN","description":"Top 20 negative significant genes associated with schwannoma tumors."} {"geneset":"DASU_IL6_SIGNALING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DASU_IL6_SIGNALING_UP","description":"Genes up-regulated in normal fibroblasts in response to IL6 [GeneID=3569]."} {"geneset":"DASU_IL6_SIGNALING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DASU_IL6_SIGNALING_DN","description":"Genes down-regulated in normal fibroblasts in response to IL6 [GeneID=3569]."} {"geneset":"BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_24HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_24HR_DN","description":"Genes down-regulated in A172 cells (glioma, does not express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 24 h."} {"geneset":"BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_24HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_24HR_UP","description":"Genes up-regulated in T98G cells (glioma, express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 24 h."} {"geneset":"HOFFMAN_CLOCK_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMAN_CLOCK_TARGETS_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) upon knockdown of CLOCK [GeneID=9575] by RNAi that also belong to the highest confidence network (according to Ingenuity Pathway Analysis)."} {"geneset":"HOFFMAN_CLOCK_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOFFMAN_CLOCK_TARGETS_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) upon knockdown of CLOCK [GeneID=9575] by RNAi that also belong to the highest confidence network (according to Ingenuity Pathway Analysis)."} {"geneset":"WHITFIELD_CELL_CYCLE_LITERATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITFIELD_CELL_CYCLE_LITERATURE","description":"A list of known cell cycle regulated genes that was compiled from the literature by the authors."} {"geneset":"JIANG_HYPOXIA_VIA_VHL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JIANG_HYPOXIA_VIA_VHL","description":"Genes up-regulated in 786-0 cells (renal carcinoma, RCC) by the loss of VHL [GeneID=7428] and in response to hypoxia."} {"geneset":"WU_APOPTOSIS_BY_CDKN1A_VIA_TP53","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_APOPTOSIS_BY_CDKN1A_VIA_TP53","description":"Genes downstream of both CDKN1A and TP53 [GeneID=1026;7157] in 2774qw1 cells (ovarian cancer)."} {"geneset":"WU_APOPTOSIS_BY_CDKN1A_NOT_VIA_TP53","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WU_APOPTOSIS_BY_CDKN1A_NOT_VIA_TP53","description":"Genes downstream of CDKN1A [GeneID=1026] in a TP53 [GeneID=7157] independent pathway in 2774qw1 cells (ovarian cancer)."} {"geneset":"ONGUSAHA_BRCA1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONGUSAHA_BRCA1_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) lacking TP53 and BRCA1 [GeneID=7157;672] by expression of BRCA1."} {"geneset":"ONGUSAHA_BRCA1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ONGUSAHA_BRCA1_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) lacking TP53 and BRCA1 [GeneID=7157;672] by expression of BRCA1."} {"geneset":"SASSON_RESPONSE_TO_GONADOTROPHINS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASSON_RESPONSE_TO_GONADOTROPHINS_UP","description":"Genes up-regulated in primary granulosa cells after stimulation with LH or FSH gonadotrophic hormones for 24 h."} {"geneset":"SASSON_RESPONSE_TO_GONADOTROPHINS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASSON_RESPONSE_TO_GONADOTROPHINS_DN","description":"Genes down-regulated in primary granulosa cells after stimulation with LH or FSH gonadotrophic hormones for 24 h."} {"geneset":"SASSON_RESPONSE_TO_FORSKOLIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASSON_RESPONSE_TO_FORSKOLIN_UP","description":"Genes up-regulated in primary granulosa cells in response to forskolin [PubChem=47936]."} {"geneset":"SASSON_RESPONSE_TO_FORSKOLIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SASSON_RESPONSE_TO_FORSKOLIN_DN","description":"Genes down-regulated in primary granulosa cells in response to forskolin [PubChem=47936]."} {"geneset":"BAE_BRCA1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAE_BRCA1_TARGETS_UP","description":"Genes concordantly up-regulated in DU-145 and MCF-7 cells (lprostate, breast cancer) upon expression of BRCA1."} {"geneset":"BAE_BRCA1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAE_BRCA1_TARGETS_DN","description":"Genes concordantly down-regulated in DU-145 and MCF-7 cells (lprostate, breast cancer) upon expression of BRCA1."} {"geneset":"BROWNE_HCMV_INFECTION_30MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_30MIN_UP","description":"Genes up-regulated in primary fibroblast cell culture at 30 min time point after infection with HCMV (AD169 strain)."} {"geneset":"BROWNE_HCMV_INFECTION_30MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_30MIN_DN","description":"Genes down-regulated in primary fibroblast cell culture at 30 min time point after infection with HCMV (AD169 strain)."} {"geneset":"BROWNE_HCMV_INFECTION_1HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_1HR_UP","description":"Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 1 h time point that were not up-regulated at the previous time point, 30 min."} {"geneset":"BROWNE_HCMV_INFECTION_1HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_1HR_DN","description":"Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 1 h time point that were not down-regulated at the previous time point, 30 min."} {"geneset":"BROWNE_HCMV_INFECTION_2HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_2HR_UP","description":"Genes up-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 2 h time point that were not up-regulated at the previous time point, 1 h."} {"geneset":"BROWNE_HCMV_INFECTION_2HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_2HR_DN","description":"Genes down-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 2 h time point that were not down-regulated at the previous time point, 1 h."} {"geneset":"BROWNE_HCMV_INFECTION_4HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_4HR_UP","description":"Genes up-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 4 h time point that were not up-regulated at the previous time point, 2 h."} {"geneset":"BROWNE_HCMV_INFECTION_4HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BROWNE_HCMV_INFECTION_4HR_DN","description":"Genes down-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 4 h time point that were not down-regulated at the previous time point, 2 h."} {"geneset":"WHITFIELD_CELL_CYCLE_G1_S","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITFIELD_CELL_CYCLE_G1_S","description":"Genes periodically expressed in synchronized HeLa cells (cervical carcinoma), with peak during the G1/S phase of cell cycle."} {"geneset":"WHITFIELD_CELL_CYCLE_S","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITFIELD_CELL_CYCLE_S","description":"Genes periodically expressed in synchronized HeLa cells (cervical carcinoma), with peak during the S phase of cell cycle."} {"geneset":"WHITFIELD_CELL_CYCLE_G2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITFIELD_CELL_CYCLE_G2","description":"Genes periodically expressed in synchronized HeLa cells (cervical carcinoma), with peak during the G2 phase of cell cycle."} {"geneset":"WHITFIELD_CELL_CYCLE_G2_M","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITFIELD_CELL_CYCLE_G2_M","description":"Genes periodically expressed in synchronized HeLa cells (cervical carcinoma), with peak during the G2/M phase of cell cycle."} {"geneset":"WHITFIELD_CELL_CYCLE_M_G1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHITFIELD_CELL_CYCLE_M_G1","description":"Genes periodically expressed in synchronized HeLa cells (cervical carcinoma), with peak during the M/G1 phase of cell cycle."} {"geneset":"RAGHAVACHARI_PLATELET_SPECIFIC_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAGHAVACHARI_PLATELET_SPECIFIC_GENES","description":"Genes in this set correspond to the most abuntant transcripts that are also specific to platelets."} {"geneset":"KARLSSON_TGFB1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KARLSSON_TGFB1_TARGETS_UP","description":"Genes up-regulated by TGFB1 [GeneID=7040] in MEF cells (embryonic fibroblast) via TGFB1R [GeneID=7046]."} {"geneset":"KARLSSON_TGFB1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KARLSSON_TGFB1_TARGETS_DN","description":"Genes down-regulated by TGFB1 [GeneID=7040] in MEF cells (embryonic fibroblast) via TGFB1R [GeneID=7046]."} {"geneset":"WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP","description":"Genes whose expression in primary ER(+) [GeneID=2099] breast cancer tumors positively correlates with developing distant metastases."} {"geneset":"WANG_METASTASIS_OF_BREAST_CANCER_ESR1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_METASTASIS_OF_BREAST_CANCER_ESR1_DN","description":"Genes whose expression in primary ER(+) [GeneID=2099] breast cancer tumors negatively correlates with developing distant metastases."} {"geneset":"WANG_METASTASIS_OF_BREAST_CANCER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_METASTASIS_OF_BREAST_CANCER","description":"Genes whose expression in primary ER(-) [GeneID=2099] breast cancer tumors negatively correlates with developing distant metastases."} {"geneset":"LI_INDUCED_T_TO_NATURAL_KILLER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_INDUCED_T_TO_NATURAL_KILLER_UP","description":"Genes up-regulated in ITNK cells (T-lymphocyte progenitors (DN3 cells) reprogrammed to natural killer (NK) cells by ablation of BCL11B [GeneID=64919] gene), compared to the parental DN3 cells."} {"geneset":"LI_INDUCED_T_TO_NATURAL_KILLER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_INDUCED_T_TO_NATURAL_KILLER_DN","description":"Genes down-regulated in ITNK cells (T-lymphocyte progenitors (DN3 cells) reprogrammed to natural killer (NK) cells by ablation of BCL11B [GeneID=64919] gene), compared to the parental DN3 cells."} {"geneset":"NOUSHMEHR_GBM_SOMATIC_MUTATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOUSHMEHR_GBM_SOMATIC_MUTATED","description":"Genes showing significantly elevated somatic mutation frequencies in proneural G-CIMP (a CpG island methylator phenotype) GBM (glyoblastoma multiforme) tumors."} {"geneset":"NOUSHMEHR_GBM_GERMLINE_MUTATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOUSHMEHR_GBM_GERMLINE_MUTATED","description":"Genes with significantl germline mutation differences in proneural G-CIMP (a CpG island methylator phenotype) GBM (glyoblastoma multiforme) tumors."} {"geneset":"NOUSHMEHR_GBM_SILENCED_BY_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOUSHMEHR_GBM_SILENCED_BY_METHYLATION","description":"Top 50 most differentially hypermethylated and down-regulated genes in proneural G-CIMP (a CpG island methylator phenotype) GBM (glyoblastoma multiforme) tumors."} {"geneset":"KAMIKUBO_MYELOID_CEBPA_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAMIKUBO_MYELOID_CEBPA_NETWORK","description":"Network of differentially expressed myeloid genes centered around CEBPA [GeneID=1050]."} {"geneset":"KAMIKUBO_MYELOID_MN1_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAMIKUBO_MYELOID_MN1_NETWORK","description":"Network of differentially expressed myeloid genes centered around MN1 [GeneID=4330]."} {"geneset":"MARTENS_BOUND_BY_PML_RARA_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTENS_BOUND_BY_PML_RARA_FUSION","description":"Genes with promoters occupied by PML-RARA fusion [GeneID=5371,5914] protein in acute promyelocytic leukemia(APL) cells NB4 and two APL primary blasts, based on Chip-seq data."} {"geneset":"MARTENS_TRETINOIN_RESPONSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTENS_TRETINOIN_RESPONSE_UP","description":"Genes up-regulated in NB4 cells (acute promyelocytic leukemia, APL) in response to tretinoin [PubChem=444795]; based on Chip-seq data."} {"geneset":"MARTENS_TRETINOIN_RESPONSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MARTENS_TRETINOIN_RESPONSE_DN","description":"Genes down-regulated in NB4 cells (acute promyelocytic leukemia, APL) in response to tretinoin [PubChem=444795]; based on Chip-seq data."} {"geneset":"STAMBOLSKY_BOUND_BY_MUTATED_TP53","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAMBOLSKY_BOUND_BY_MUTATED_TP53","description":"Gene promoters preferentially bound by a mutated form of TP53 [GeneID=7157] in SKBR3 cells (breast cancer)."} {"geneset":"STAMBOLSKY_TARGETS_OF_MUTATED_TP53_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAMBOLSKY_TARGETS_OF_MUTATED_TP53_UP","description":"Genes induced in SKBR3 cells (breast cancer) by mutated TP53 [GeneID=7157]."} {"geneset":"STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN","description":"Genes repressed in SKBR3 cells (breast cancer) by mutated TP53 [GeneID=7157]."} {"geneset":"STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_UP","description":"Genes induced in SKBR3 cells (breast cancer) by 25-hydroxyvitamin D3 [PubChem=1593]."} {"geneset":"STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_DN","description":"Genes repressed in SKBR3 cells (breast cancer) by 25-hydroxyvitamin D3 [PubChem=1593]."} {"geneset":"KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP","description":"Genes whose expression was significantly and positively correlated with the number of perineuronal oligodendrocytes in the layer III of BA9 brain region."} {"geneset":"KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_DN","description":"Genes whose expression was significantly and negatively correlated with the number of perineuronal oligodendrocytes in the layer III of BA9 brain region."} {"geneset":"KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP","description":"Genes whose expression significantly and positively correlated with oligodendrocyte density in layer VI of BA9 brain region in patients with bipolar disorder."} {"geneset":"KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN","description":"Genes whose expression significantly and negatively correlated with oligodendrocyte density in layer VI of BA9 brain region in patients with bipolar disorder."} {"geneset":"KIM_ALL_DISORDERS_CALB1_CORR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_ALL_DISORDERS_CALB1_CORR_UP","description":"Genes whose expression significantly and positively correlated with the density of CALB1-positive [GeneID=793] GABAergic interneurons in the BA9 brain region across all subjects with psychiatric disorders."} {"geneset":"KIM_ALL_DISORDERS_CALB1_CORR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_ALL_DISORDERS_CALB1_CORR_DN","description":"Genes whose expression significantly and negatively correlated with the density of CALB1-positive [GeneID=793] GABAergic interneurons in the BA9 brain region across all subjects with psychiatric disorders."} {"geneset":"KIM_ALL_DISORDERS_DURATION_CORR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_ALL_DISORDERS_DURATION_CORR_UP","description":"Genes whose expression in brain significantly and positively correlated with the duration of all psychiatric disorders studied."} {"geneset":"KIM_ALL_DISORDERS_DURATION_CORR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_ALL_DISORDERS_DURATION_CORR_DN","description":"Genes whose expression in brain significantly and negatively correlated with the duration of all psychiatric disorders studied."} {"geneset":"VERHAAK_GLIOBLASTOMA_PRONEURAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERHAAK_GLIOBLASTOMA_PRONEURAL","description":"Genes correlated with proneural type of glioblastoma multiforme tumors."} {"geneset":"VERHAAK_GLIOBLASTOMA_NEURAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERHAAK_GLIOBLASTOMA_NEURAL","description":"Genes correlated with neural type of glioblastoma multiforme tumors."} {"geneset":"VERHAAK_GLIOBLASTOMA_CLASSICAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERHAAK_GLIOBLASTOMA_CLASSICAL","description":"Genes correlated with classical type of glioblastoma multiforme tumors."} {"geneset":"VERHAAK_GLIOBLASTOMA_MESENCHYMAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERHAAK_GLIOBLASTOMA_MESENCHYMAL","description":"Genes correlated with mesenchymal type of glioblastoma multiforme tumors."} {"geneset":"HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP","description":"Up-regulated genes in the cancer gene signature, representing a gene signature of cellular transformation."} {"geneset":"HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN","description":"Down-regulated genes in the cancer gene signature, representing a gene signature of cellular transformation."} {"geneset":"CHICAS_RB1_TARGETS_SENESCENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHICAS_RB1_TARGETS_SENESCENT","description":"Genes up-regulated in senescent IMR90 cells (fibroblast) after knockdown of RB1 [GeneID=5925] by RNAi."} {"geneset":"CHICAS_RB1_TARGETS_LOW_SERUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHICAS_RB1_TARGETS_LOW_SERUM","description":"Genes up-regulated in IMR90 cells (fibroblast) grown under low serum conditions and after knockdown of RB1 [GeneID=5925] by RNAi."} {"geneset":"CHICAS_RB1_TARGETS_GROWING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHICAS_RB1_TARGETS_GROWING","description":"Genes up-regulated in growing IMR90 cells (fibroblast) after knockdown of RB1 [GeneID=5925] by RNAi."} {"geneset":"CHICAS_RB1_TARGETS_CONFLUENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHICAS_RB1_TARGETS_CONFLUENT","description":"Genes up-regulated in confluent IMR90 cells (fibroblast) after knockdown of RB1 [GeneID=5925] by RNAi."} {"geneset":"WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP","description":"Genes up-regulated in RS4;11 cells (MLL, mixed lineage leukemia) in response to SB216763 [PubChem=176158], an inhibitor of GSK3B [GeneID=2932]."} {"geneset":"WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN","description":"Genes down-regulated in RS4;11 cells (MLL, mixed lineage leukemia) in response to SB216763 [PubChem=176158], an inhibitor of GSK3B [GeneID=2932]."} {"geneset":"QI_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/QI_HYPOXIA","description":"Genes up-regulated by hypoxia in TRAMP-C cells (prostatic cancer)."} {"geneset":"QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2","description":"Genes up-regulated by hypoxia in TRAMP-C cells (prostatic cancer) expressing HIF1A and FOXA2 [GeneID=3091,3170] off plasmid vectors."} {"geneset":"GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB","description":"Genes identified as synthetic lethal with imatinib [PubChem=5291] in RNAi screen in K562 cells (CML, chronic myelogenous leukemia)."} {"geneset":"LU_EZH2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_EZH2_TARGETS_UP","description":"Genes up-regulated in SKOV3ip1 cells (ovarian cancer) upon knockdown of EZH2 [GeneID=2146] by RNAi."} {"geneset":"LU_EZH2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LU_EZH2_TARGETS_DN","description":"Genes down-regulated in SKOV3ip1 cells (ovarian cancer) upon knockdown of EZH2 [GeneID=2146] by RNAi."} {"geneset":"HOELZEL_NF1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOELZEL_NF1_TARGETS_UP","description":"Genes up-regulated in SH-SY5Y cells (neuroblastoma) after knockdown of NF1 [GeneID=4763] by RNAi."} {"geneset":"HOELZEL_NF1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOELZEL_NF1_TARGETS_DN","description":"Genes down-regulated in SH-SY5Y cells (neuroblastoma) after knockdown of NF1 [GeneID=4763] by RNAi."} {"geneset":"DEMAGALHAES_AGING_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DEMAGALHAES_AGING_UP","description":"Genes consistently overexpressed with age, based on meta-analysis of microarray data."} {"geneset":"DEMAGALHAES_AGING_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DEMAGALHAES_AGING_DN","description":"Genes consistently underexpressed with age, based on meta-analysis of microarray data."} {"geneset":"DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) at 6 h of estradiol [PubChem=5757] treatment."} {"geneset":"DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) at 6 h of estradiol [PubChem=5757] treatment."} {"geneset":"DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP","description":"Genes up-regulated in MCF7 cells (breast cancer) at 24 h of estradiol [PubChem=5757] treatment."} {"geneset":"DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN","description":"Genes down-regulated in MCF7 cells (breast cancer) at 24 h of estradiol [PubChem=5757] treatment."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_1_UP","description":"Cluster 1 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_1_DN","description":"Cluster 1 of aberrantly hypomethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_2_UP","description":"Cluster 2 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_2_DN","description":"Cluster 2 of aberrantly hypomethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_3_UP","description":"Cluster 3 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_3_DN","description":"Cluster 3 of aberrantly hypomethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_4_UP","description":"Cluster 4 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_4_DN","description":"Cluster 4 of aberrantly hypomethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_5_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_5_UP","description":"Cluster 5 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_5_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_5_DN","description":"Cluster 5 of aberrantly hypomethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_6_UP","description":"Cluster 6 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_6_DN","description":"Cluster 6 of aberrantly hypomethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_7_UP","description":"Cluster 7 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"FIGUEROA_AML_METHYLATION_CLUSTER_7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FIGUEROA_AML_METHYLATION_CLUSTER_7_DN","description":"Cluster 7 of aberrantly hypomethylated genes in blasts from AML (acute myeloid leukemia) patients."} {"geneset":"WANG_CLASSIC_ADIPOGENIC_TARGETS_OF_PPARG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_CLASSIC_ADIPOGENIC_TARGETS_OF_PPARG","description":"Classic adipogenic genes (group 1) that are induced by PPARG [GeneID=5468] during adipogenesis in 3T3-L1 preadipocytes."} {"geneset":"WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1","description":"Adipogenic genes (group 2) that are selectively repressed by SIRT1 [GeneID=23411] in mature 3T3-L1 adipocytes."} {"geneset":"PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP","description":"Genes up-regulated in ovarian tumors from mouse models for the BMP SMAD signaling (gonad specific double knockout of SMAD1 and SMAD5 [GeneID=4086, 4090])."} {"geneset":"PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN","description":"Genes down-regulated in ovarian tumors from mouse models for the BMP SMAD signaling (gonad specific double knockout of SMAD1 and SMAD5 [GeneID=4086, 4090])."} {"geneset":"TSUTSUMI_FBXW8_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TSUTSUMI_FBXW8_TARGETS","description":"Genes differentially expressed in E18.5 whole embryos upon knockout of FBXW8 [GeneID=26259]."} {"geneset":"LI_DCP2_BOUND_MRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LI_DCP2_BOUND_MRNA","description":"Genes encoding mRNA transcripts specifically bound by DCP2 [GeneID=167227]."} {"geneset":"WAGSCHAL_EHMT2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAGSCHAL_EHMT2_TARGETS_UP","description":"Genes up-regulated in placenta of mice with EHMT2 [GeneID=10919] knocked out."} {"geneset":"SUBTIL_PROGESTIN_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUBTIL_PROGESTIN_TARGETS","description":"Genes responding to progestin R5020 [PubChem=36709] treatment of T47D-MTVL cells (breast cancer)."} {"geneset":"OHGUCHI_LIVER_HNF4A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OHGUCHI_LIVER_HNF4A_TARGETS_UP","description":"Genes up-regulated in liver samples of liver-specific knockout of HNF4A [GeneID=3172]."} {"geneset":"OHGUCHI_LIVER_HNF4A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OHGUCHI_LIVER_HNF4A_TARGETS_DN","description":"Genes down-regulated in liver samples of liver-specific knockout of HNF4A [GeneID=3172]."} {"geneset":"GABRIELY_MIR21_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GABRIELY_MIR21_TARGETS","description":"Genes significantly de-regulated (p < 0.05) by MIR21 [GeneID=406991] in A172 cells (glioma)."} {"geneset":"THILLAINADESAN_ZNF217_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THILLAINADESAN_ZNF217_TARGETS_UP","description":"Genes bound and activated by ZNF217 [GeneID=7764] in MCF7 cells (breast cancer)."} {"geneset":"THILLAINADESAN_ZNF217_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/THILLAINADESAN_ZNF217_TARGETS_DN","description":"Genes bound and repressed by ZNF217 [GeneID=7764] in MCF7 cells (breast cancer)."} {"geneset":"PHESSE_TARGETS_OF_APC_AND_MBD2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PHESSE_TARGETS_OF_APC_AND_MBD2_UP","description":"Genes up-regulated in small intestine upon loss of both APC and MBD2 [GeneID=324, 8932]."} {"geneset":"PHESSE_TARGETS_OF_APC_AND_MBD2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PHESSE_TARGETS_OF_APC_AND_MBD2_DN","description":"Genes down-regulated in small intestine upon loss of both APC and MBD2 [GeneID=324, 8932]."} {"geneset":"CHYLA_CBFA2T3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHYLA_CBFA2T3_TARGETS_UP","description":"Genes up-regulated in immature bone marrow progenitor cells upon knock out of CBFA2T3 [GeneID=863]."} {"geneset":"CHYLA_CBFA2T3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHYLA_CBFA2T3_TARGETS_DN","description":"Genes down-regulated in immature bone marrow progenitor cells upon knock out of CBFA2T3 [GeneID=863]."} {"geneset":"FUKUSHIMA_TNFSF11_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FUKUSHIMA_TNFSF11_TARGETS","description":"Genes up-regulated in RAW 264.7 cells (macrophage) upon stimulation with TNFSF11 [GeneID=8600]."} {"geneset":"CARD_MIR302A_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CARD_MIR302A_TARGETS","description":"Potential targets of MIR302A [GeneID=407028]."} {"geneset":"WIERENGA_STAT5A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIERENGA_STAT5A_TARGETS_UP","description":"Genes up-regulated in CD34+ [GeneID=947] cells by intermediate activity levels of STAT5A [GeneID=6776]; predominant long-term growth and self-renewal phenotype."} {"geneset":"WIERENGA_STAT5A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIERENGA_STAT5A_TARGETS_DN","description":"Genes down-regulated in CD34+ [GeneID=947] cells by intermediate activity levels of STAT5A [GeneID=6776]; predominant long-term growth and self-renewal phenotype."} {"geneset":"WIERENGA_STAT5A_TARGETS_GROUP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIERENGA_STAT5A_TARGETS_GROUP1","description":"Genes up-regulated to their maximal levels in CD34+ [GeneID=947] cells by intermediate activity levels of STAT5A [GeneID=6776]; predominant long-term growth and self-renewal phenotype."} {"geneset":"WIERENGA_STAT5A_TARGETS_GROUP2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIERENGA_STAT5A_TARGETS_GROUP2","description":"Genes up-regulated in a linear fashion in CD34+ [GeneID=947] cells upon increasing activity levels of STAT5A [GeneID=6776]; predominant long-term growth and self-renewal phenotype."} {"geneset":"WIERENGA_PML_INTERACTOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIERENGA_PML_INTERACTOME","description":"Proteins identified in complex with PML [GeneID=5371] in K562 cells (lymphoblast)."} {"geneset":"ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP","description":"Genes up-regulated in K562 cells (lymphoblast) by MYC [GeneID=4609] in the presence of CKN1B [GeneID=1027]."} {"geneset":"ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN","description":"Genes down-regulated in K562 cells (lymphoblast) by MYC [GeneID=4609] in the presence of CKN1B [GeneID=1027]."} {"geneset":"KANG_AR_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_AR_TARGETS_UP","description":"Genes up-regulated in osteoblasts from wild type male mice compared to those with AR [GeneID=367] knockout."} {"geneset":"KANG_AR_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_AR_TARGETS_DN","description":"Genes down-regulated in osteoblasts from wild type male mice compared to those with AR [GeneID=367] knockout."} {"geneset":"PILON_KLF1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PILON_KLF1_TARGETS_UP","description":"Genes up-regulated in erythroid progenitor cells from fetal livers of E13.5 embryos with KLF1 [GeneID=10661] knockout compared to those from the wild type embryos."} {"geneset":"PILON_KLF1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PILON_KLF1_TARGETS_DN","description":"Genes down-regulated in erythroid progenitor cells from fetal livers of E13.5 embryos with KLF1 [GeneID=10661] knockout compared to those from the wild type embryos."} {"geneset":"BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP","description":"Genes bound by ESR1 [GeneID=2099] and up-regulated by estradiol [PubChem=5757] in MCF-7 cells (breast cancer)."} {"geneset":"BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN","description":"Genes bound by ESR1 [GeneID=2099] and down-regulated by estradiol [PubChem=5757] in MCF-7 cells (breast cancer)."} {"geneset":"BHAT_ESR1_TARGETS_VIA_AKT1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BHAT_ESR1_TARGETS_VIA_AKT1_UP","description":"Genes bound by ESR1 [GeneID=2099] and up-regulated by estradiol [PubChem=5757] in MCF-7 cells (breast cancer) expressing constitutevly active form of AKT1 [GeneID=207]."} {"geneset":"BHAT_ESR1_TARGETS_VIA_AKT1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BHAT_ESR1_TARGETS_VIA_AKT1_DN","description":"Genes bound by ESR1 [GeneID=2099] and down-regulated by estradiol [PubChem=5757] in MCF-7 cells (breast cancer) expressing constitutevly active form of AKT1 [GeneID=207]."} {"geneset":"JOHNSTONE_PARVB_TARGETS_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHNSTONE_PARVB_TARGETS_1_UP","description":"Genes up-regulated in MDA-MB-231 cells (breast cancer) upon overexpression of PARVB [GeneID=29780] under all three culture conditions."} {"geneset":"JOHNSTONE_PARVB_TARGETS_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHNSTONE_PARVB_TARGETS_1_DN","description":"Genes down-regulated in MDA-MB-231 cells (breast cancer) upon overexpression of PARVB [GeneID=29780] under all three culture conditions."} {"geneset":"JOHNSTONE_PARVB_TARGETS_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHNSTONE_PARVB_TARGETS_2_UP","description":"Genes up-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D collagen I and 3D Matrigel only."} {"geneset":"JOHNSTONE_PARVB_TARGETS_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHNSTONE_PARVB_TARGETS_2_DN","description":"Genes down-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D collagen I and 3D Matrigel only."} {"geneset":"JOHNSTONE_PARVB_TARGETS_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHNSTONE_PARVB_TARGETS_3_UP","description":"Genes up-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D Matrigel only."} {"geneset":"JOHNSTONE_PARVB_TARGETS_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JOHNSTONE_PARVB_TARGETS_3_DN","description":"Genes down-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D Matrigel only."} {"geneset":"BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A","description":"Category A genes: p53-dependent genes whose expression in the absence of S389 phosphorylation is similar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation."} {"geneset":"BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B","description":"Category B genes: p53-dependent genes whose expression in the absence of S389 phosphorylation is dissimilar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation."} {"geneset":"BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_C","description":"Category C genes: p53-independent genes whose expression in the absence of S389 phosphorylation is dissimilar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation."} {"geneset":"BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D","description":"Category D genes: p53-independent genes whose expression in the absence of S389 phosphorylation is similar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation."} {"geneset":"BRUINS_UVC_RESPONSE_LATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUINS_UVC_RESPONSE_LATE","description":"Late response genes: differentially expressed only 12 h after UV-C irradiation of MEF cells (embryonic fibroblast)."} {"geneset":"BRUINS_UVC_RESPONSE_EARLY_LATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUINS_UVC_RESPONSE_EARLY_LATE","description":"Early-late response genes: differentially expressed in the first 3 h and after 12 h following UV-C irradiation of MEF cells (embryonic fibroblast)."} {"geneset":"BRUINS_UVC_RESPONSE_MIDDLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRUINS_UVC_RESPONSE_MIDDLE","description":"Middle response genes: differentially expressed in the period between 3 h and 12 h after UV-C irradiation of MEF cells (embryonic fibroblast)."} {"geneset":"CERIBELLI_PROMOTERS_INACTIVE_AND_BOUND_BY_NFY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CERIBELLI_PROMOTERS_INACTIVE_AND_BOUND_BY_NFY","description":"Transcriptionally inactive genes whose promoters (regions between -2 kb to +0.5 kb relative to trascription start sites) where bound by NF-Y transcription factor."} {"geneset":"CERIBELLI_GENES_INACTIVE_AND_BOUND_BY_NFY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CERIBELLI_GENES_INACTIVE_AND_BOUND_BY_NFY","description":"Transcriptionally inactive genes which where bound by NF-Y transcription factor."} {"geneset":"MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP","description":"Genes commonly up-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]."} {"geneset":"MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN","description":"Genes commonly down-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]."} {"geneset":"IVANOVSKA_MIR106B_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IVANOVSKA_MIR106B_TARGETS","description":"A consensus set of genes that were significantly down-regulated by MIR106B [GeneID=406900]."} {"geneset":"KIM_GLIS2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_GLIS2_TARGETS_UP","description":"Partial list of genes up-regulated in the kidney of GLIS2 [GeneID=84662] knockout mice compared to the wild type."} {"geneset":"KIM_GLIS2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_GLIS2_TARGETS_DN","description":"Partial list of genes down-regulated in the kidney of GLIS2 [GeneID=84662] knockout mice compared to the wild type."} {"geneset":"MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_UP","description":"Proteins significantly induced by oxidative stress (hydrogen peroxide [PubChem=784] in 786-O cells (renal clear cell carcinoma, RCC) expressing VHL [GeneID=7428]."} {"geneset":"MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_DN","description":"Proteins significantly repressed by oxidative stress (hydrogen peroxide [PubChem=784] in 786-O cells (renal clear cell carcinoma, RCC) expressing VHL [GeneID=7428]."} {"geneset":"STEGER_ADIPOGENESIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEGER_ADIPOGENESIS_UP","description":"Genes up-regulated during adipogenesis of 3T3-L1 cells (fibroblast)."} {"geneset":"STEGER_ADIPOGENESIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEGER_ADIPOGENESIS_DN","description":"Genes down-regulated during adipogenesis of 3T3-L1 cells (fibroblast)."} {"geneset":"ZHU_SKIL_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHU_SKIL_TARGETS_UP","description":"Genes up-regulated in A549 cells (lung adenocarcinoma) upon SKIL [GeneID=6498] knockdown by RNAi."} {"geneset":"ZHU_SKIL_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHU_SKIL_TARGETS_DN","description":"Genes down-regulated in A549 cells (lung adenocarcinoma) upon SKIL [GeneID=6498] knockdown by RNAi."} {"geneset":"KIM_PTEN_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_PTEN_TARGETS_UP","description":"Genes up-regulated in HCT116 cells (colorectal carcinoma) upon knockout of PTEN [GeneID=5728]."} {"geneset":"KIM_PTEN_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_PTEN_TARGETS_DN","description":"Genes down-regulated in HCT116 cells (colorectal carcinoma) upon knockout of PTEN [GeneID=5728]."} {"geneset":"ISHIDA_TARGETS_OF_SYT_SSX_FUSIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ISHIDA_TARGETS_OF_SYT_SSX_FUSIONS","description":"Genes down-regulated in synovial sarcoma samples with SYT-SSX fusions resulting from translocation of SS18 [GeneID=SS18] to one of the SSX genes."} {"geneset":"MAEKAWA_ATF2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAEKAWA_ATF2_TARGETS","description":"Genes down-regulated in MEF cells (embryonic fibroblast) upon knockout of ATF2 [GeneID=1386]."} {"geneset":"ISSAEVA_MLL2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ISSAEVA_MLL2_TARGETS","description":"Genes down-regulated in HeLa cells upon knockdown of MLL2 [GeneID=8085] by RNAi."} {"geneset":"LINSLEY_MIR16_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LINSLEY_MIR16_TARGETS","description":"Transcripts down-regulated by overexpression of MIR16 family of microRNA molecules in DLD-1 and HCT116 (colon cancer) cells hypomorphic for DICER1 [GeneID=23405]."} {"geneset":"CHENG_TAF7L_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHENG_TAF7L_TARGETS","description":"Genes down-regulated in testis tissues upon knockout of TAF7L [GeneID=54457]."} {"geneset":"CHANGOLKAR_H2AFY_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANGOLKAR_H2AFY_TARGETS_UP","description":"Genes up-regulated in liver tissue upon knockout of H2AFY [GeneID=9555]."} {"geneset":"CHANGOLKAR_H2AFY_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHANGOLKAR_H2AFY_TARGETS_DN","description":"Genes down-regulated in liver tissue upon knockout of H2AFY [GeneID=9555]."} {"geneset":"PASINI_SUZ12_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PASINI_SUZ12_TARGETS_UP","description":"Genes up-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]."} {"geneset":"PASINI_SUZ12_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PASINI_SUZ12_TARGETS_DN","description":"Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]."} {"geneset":"BAKKER_FOXO3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAKKER_FOXO3_TARGETS_UP","description":"Genes up-regulated in I/11 erythroblast cells upon expression of an activated form of FOXO3 [GeneID=2309]."} {"geneset":"BAKKER_FOXO3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BAKKER_FOXO3_TARGETS_DN","description":"Genes down-regulated in I/11 erythroblast cells upon expression of an activated form of FOXO3 [GeneID=2309]."} {"geneset":"BERGER_MBD2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BERGER_MBD2_TARGETS","description":"Genes strongly up-regulated in colon tissue upon MBD2 [GeneID=8932] knockout."} {"geneset":"VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP","description":"Genes up-regulated in 9.5 days post coitus (dpc) embryos with COMMD1 [GeneID=150684] knockout compared to normal 8.5 dpc and 9.5 dpc embryos."} {"geneset":"VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP","description":"Genes up-regulated in 9.5 days post coitus (dpc) embryos with COMMD1 [GeneID=150684] knockout compared to normal 9.5 dpc embryos."} {"geneset":"VANDESLUIS_COMMD1_TARGETS_GROUP_3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANDESLUIS_COMMD1_TARGETS_GROUP_3_DN","description":"Genes down-regulated in 9.5 days post coitus (dpc) embryos with COMMD1 [GeneID=150684] knockout compared to normal 9.5 dpc embryos."} {"geneset":"VANDESLUIS_COMMD1_TARGETS_GROUP_4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANDESLUIS_COMMD1_TARGETS_GROUP_4_UP","description":"Genes up-regulated in 9.5 days post coitus (dpc) embryos with COMMD1 [GeneID=150684] knockout and in normal 8.5 dpc embryos compared to normal 9.5 dpc embryos."} {"geneset":"VANDESLUIS_COMMD1_TARGETS_GROUP_4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANDESLUIS_COMMD1_TARGETS_GROUP_4_DN","description":"Genes down-regulated in 9.5 days post coitus (dpc) embryos with COMMD1 [GeneID=150684] knockout and in normal 8.5 dpc embryos compared to normal 9.5 dpc embryos."} {"geneset":"VANDESLUIS_NORMAL_EMBRYOS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANDESLUIS_NORMAL_EMBRYOS_UP","description":"Genes up-regulated in normal 9.5 days post coitus (dpc) embryos compared to normal 8.5 dpc and 9.5 dpc embryos."} {"geneset":"VANDESLUIS_NORMAL_EMBRYOS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANDESLUIS_NORMAL_EMBRYOS_DN","description":"Genes down-regulated in normal 9.5 days post coitus (dpc) embryos compared to normal 8.5 dpc and 9.5 dpc embryos."} {"geneset":"SUMI_HNF4A_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUMI_HNF4A_TARGETS","description":"Genes up-regulated in HepG2 cells (hepatocellular carcinoma, HCC) upon expression of HNF4A [GeneID=3172] and down-regulated upon knockdown of HNF4A [GeneID=3172] in these cells by RNAi."} {"geneset":"WANG_NFKB_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_NFKB_TARGETS","description":"Representative genes up-regulated in C2C12 cells (myoblast) lacking NFkB activity due to expression of a super repressor form of NFKBIA [GeneID=4792]."} {"geneset":"WANG_TNF_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_TNF_TARGETS","description":"Representative genes up-regulated in MEF cells (embryonic fibroblast) in response to TNF [GeneID=7124]."} {"geneset":"AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP","description":"Genes up-regulated in RWPE-1 cells (prostate cancer) upon expression of constitutively active form of STAT3 [GeneID=6774]."} {"geneset":"AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_DN","description":"Genes down-regulated in RWPE-1 cells (prostate cancer) upon expression of constitutively active form of STAT3 [GeneID=6774]."} {"geneset":"AZARE_STAT3_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AZARE_STAT3_TARGETS","description":"Genes up-regulated in RPWE-1 cells by activated STAT3 [GeneID=6774]."} {"geneset":"DELPUECH_FOXO3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELPUECH_FOXO3_TARGETS_UP","description":"Genes up-regulated in DL23 cells (colon cancer) upon expression of an activated form of FOXO3 [GeneID=2309]."} {"geneset":"DELPUECH_FOXO3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELPUECH_FOXO3_TARGETS_DN","description":"Genes down-regulated in DL23 cells (colon cancer) upon expression of an activated form of FOXO3 [GeneID=2309]."} {"geneset":"WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2","description":"Genes up-regulated in DAOY cells (medulloblastoma) upon knockdown of both BMI1 and PCGF2 [GeneID=648, 7703] by RNAi."} {"geneset":"KASLER_HDAC7_TARGETS_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KASLER_HDAC7_TARGETS_1_UP","description":"Genes up-regulated in DO11.10 cells (hybridoma) by expression of transciptionally activating form of HDAC7 [GeneID=51564] and down-regulated by its transcriptionally repressing form."} {"geneset":"KASLER_HDAC7_TARGETS_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KASLER_HDAC7_TARGETS_1_DN","description":"Genes down-regulated in DO11.10 cells (hybridoma) by expression of transciptionally activating form of HDAC7 [GeneID=51564] and up-regulated by its transcriptionally repressing form."} {"geneset":"KASLER_HDAC7_TARGETS_2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KASLER_HDAC7_TARGETS_2_UP","description":"Genes up-regulated in DO11.10 cells (hybridoma) by expression of transciptionally activating and by transcriptionally repressive forms of HDAC7 [GeneID=51564]."} {"geneset":"KASLER_HDAC7_TARGETS_2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KASLER_HDAC7_TARGETS_2_DN","description":"Genes down-regulated in DO11.10 cells (hybridoma) by expression of transciptionally activating and by transcriptionally repressive forms of HDAC7 [GeneID=51564]."} {"geneset":"DORMOY_ELAVL1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DORMOY_ELAVL1_TARGETS","description":"Genes down-regulated in HeLa cells upon knockdown of ELAVL1 [GeneID=1994] by RNAi."} {"geneset":"LEE_BMP2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_BMP2_TARGETS_UP","description":"Genes up-regulated in uterus upon knockout of BMP2 [GeneID=650]."} {"geneset":"LEE_BMP2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEE_BMP2_TARGETS_DN","description":"Genes down-regulated in uterus upon knockout of BMP2 [GeneID=650]."} {"geneset":"BILANGES_SERUM_SENSITIVE_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILANGES_SERUM_SENSITIVE_GENES","description":"Genes translationally regulated in MEF cells (embryonic fibroblasts) in response to serum starvation but not by rapamycin (sirolimus) [PubChem=6610346]."} {"geneset":"BILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES","description":"Genes translationally regulated in MEF cells (embryonic fibroblasts) in response to serum starvation and by rapamycin (sirolimus) [PubChem=6610346]."} {"geneset":"BILANGES_RAPAMYCIN_SENSITIVE_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILANGES_RAPAMYCIN_SENSITIVE_GENES","description":"Genes translationally regulated in MEF cells (embryonic fibroblasts) by rapamycin (sirolimus) [PubChem=6610346] but not in response to serum deprivation."} {"geneset":"BILANGES_RAPAMYCIN_SENSITIVE_VIA_TSC1_AND_TSC2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILANGES_RAPAMYCIN_SENSITIVE_VIA_TSC1_AND_TSC2","description":"Genes translationally repressed by rapamycin (sirolimus) [PubChem=6610346] in MEF cells (embryonic fibroblast) lacking either TSC1 or TSC2 [GeneID=7248, 7249] but not in the wild type cells."} {"geneset":"BILANGES_SERUM_SENSITIVE_VIA_TSC1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILANGES_SERUM_SENSITIVE_VIA_TSC1","description":"Genes translationally up-regulated by serum in MEF cells (embryonic fibroblast) lacking TSC1 [GeneID=7248]."} {"geneset":"BILANGES_SERUM_SENSITIVE_VIA_TSC2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILANGES_SERUM_SENSITIVE_VIA_TSC2","description":"Genes translationally up-regulated by serum in MEF cells (embryonic fibroblast) lacking TSC2 [GeneID=7249]."} {"geneset":"BILANGES_SERUM_RESPONSE_TRANSLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BILANGES_SERUM_RESPONSE_TRANSLATION","description":"Genes translationally repressed upon serum deprivation in MEF cells (embryonic fibroblast)."} {"geneset":"KIM_TIAL1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_TIAL1_TARGETS","description":"Top scoring genes whose transcripts bound TIAR1 [GeneID=7073] in extracts from RKO cells (colon cancer)."} {"geneset":"DUAN_PRDM5_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DUAN_PRDM5_TARGETS","description":"Direct targets of PRDM5 [GeneID=11107]."} {"geneset":"DALESSIO_TSA_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DALESSIO_TSA_RESPONSE","description":"Top genes up-regulated in HEK293 cells (fibroblast) in response to trichostatin A (TSA) [PubChem=5562]."} {"geneset":"FEVR_CTNNB1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FEVR_CTNNB1_TARGETS_UP","description":"Genes up-regulated in intestinal crypt cells upon deletion of CTNNB1 [GeneID=1499]."} {"geneset":"FEVR_CTNNB1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FEVR_CTNNB1_TARGETS_DN","description":"Genes down-regulated in intestinal crypt cells upon deletion of CTNNB1 [GeneID=1499]."} {"geneset":"FARDIN_HYPOXIA_9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARDIN_HYPOXIA_9","description":"Genes in the hypoxia signature, based on analysis of nine neuroblastoma cell lines in hypoxia and normal oxygen conditions."} {"geneset":"FARDIN_HYPOXIA_11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARDIN_HYPOXIA_11","description":"Genes in the hypoxia signature, based on analysis of 11 neuroblastoma cell lines in hypoxia and normal oxygen conditions."} {"geneset":"TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP","description":"Top 20 up-regulated genes in leukemic progenitor cells expressing activated fusion of ESWR1 and FLI1 [GeneID=2130, 2313] compared to normal hematopoetic progenitors."} {"geneset":"TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_DN","description":"Top 20 down-regulated genes in leukemic progenitor cells expressing activated fusion of ESWR1 and FLI1 [GeneID=2130, 2313] compared to normal hematopoetic progenitors."} {"geneset":"TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP","description":"Genes up-regulated in leukemic progenitor cells expressing activated fusion of ESWR1 and FLI1 [GeneID=2130, 2313] compared to normal hematopoetic progenitors."} {"geneset":"TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN","description":"Genes down-regulated in leukemic progenitor cells expressing activated fusion of ESWR1 and FLI1 [GeneID=2130, 2313] compared to normal hematopoetic progenitors."} {"geneset":"WINZEN_DEGRADED_VIA_KHSRP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WINZEN_DEGRADED_VIA_KHSRP","description":"Transcripts (mRNA molecules) rapidly degraded upon interaction with KHSRP [GeneID=8570]."} {"geneset":"VANLOO_SP3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANLOO_SP3_TARGETS_UP","description":"Genes up-regulated in E12.5 hearts from mice with SP3 [GeneID=6670] knockout compared to the wild type organ."} {"geneset":"VANLOO_SP3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANLOO_SP3_TARGETS_DN","description":"Genes down-regulated in E12.5 hearts from mice with SP3 [GeneID=6670] knockout compared to the wild type organ."} {"geneset":"YUAN_ZNF143_PARTNERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YUAN_ZNF143_PARTNERS","description":"Proteins associated with ZNF143 [GeneID=7702] in HeLa cells, based on MudPIT analysis."} {"geneset":"KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3","description":"Genes with promoters occupied by SMAD2 or SMAD3 [GeneID=4087, 4088] in HaCaT cells (keratinocyte) according to a ChIP-chip analysis."} {"geneset":"RAFFEL_VEGFA_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAFFEL_VEGFA_TARGETS_UP","description":"Genes up-regulated in hearts of E18.5 embryos upon knockout of VEGFA [GeneID=7422]."} {"geneset":"RAFFEL_VEGFA_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAFFEL_VEGFA_TARGETS_DN","description":"Genes down-regulated in hearts of E18.5 embryos upon knockout of VEGFA [GeneID=7422]."} {"geneset":"TERAO_AOX4_TARGETS_HG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAO_AOX4_TARGETS_HG_UP","description":"Genes up-regulated in Harderian gland tissue upon knockout of AOX4 [GeneID=71872]."} {"geneset":"TERAO_AOX4_TARGETS_HG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAO_AOX4_TARGETS_HG_DN","description":"Genes down-regulated in Harderian gland tissue upon knockout of AOX4 [GeneID=71872]."} {"geneset":"TERAO_AOX4_TARGETS_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAO_AOX4_TARGETS_SKIN_UP","description":"Genes up-regulated in skin upon knockout of AOX4 [GeneID=71872]."} {"geneset":"TERAO_AOX4_TARGETS_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TERAO_AOX4_TARGETS_SKIN_DN","description":"Genes down-regulated in skin upon knockout of AOX4 [GeneID=71872]."} {"geneset":"PURBEY_TARGETS_OF_CTBP1_AND_SATB1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PURBEY_TARGETS_OF_CTBP1_AND_SATB1_UP","description":"Genes up-regulated in HEK-293 cells (fibroblast) upon knockdown of both CTBP1 and SATB1 [GeneID=1487, 6304] by RNAi."} {"geneset":"PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN","description":"Genes down-regulated in HEK-293 cells (fibroblast) upon knockdown of both CTBP1 and SATB1 [GeneID=1487, 6304] by RNAi."} {"geneset":"PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP","description":"Genes up-regulated in HEK-293 cells (fibroblast) upon knockdown of CTBP1 but not of SATB1 [GeneID=1487, 6304] by RNAi."} {"geneset":"PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN","description":"Genes down-regulated in HEK-293 cells (fibroblast) upon knockdown of CTBP1 but not of SATB1 [GeneID=1487, 6304] by RNAi."} {"geneset":"GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP","description":"Genes up-regulated during later stage of differentiation of Oli-Neu cells (oligodendroglial precursor) in response to PD174265 [PubChem=4709]."} {"geneset":"GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN","description":"Genes down-regulated during differentiation of Oli-Neu cells (oligodendroglial precursor) in response to PD174265 [PubChem=4709]."} {"geneset":"GOBERT_CORE_OLIGODENDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOBERT_CORE_OLIGODENDROCYTE_DIFFERENTIATION","description":"Oligodendrocyte core differentiation genes: up-regulated in Oli-neo cells (oligodendroglial precursor) at 10 h after treatment with PD174265, dexamethasone or isotretinoin [PubChem=4709, 5743, 5282379]."} {"geneset":"WACKER_HYPOXIA_TARGETS_OF_VHL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WACKER_HYPOXIA_TARGETS_OF_VHL","description":"Genes down-regulated by VHL [GeneID=7428] and re-expressed under hypoxia conditions in renal carcinoma cells."} {"geneset":"IKEDA_MIR1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IKEDA_MIR1_TARGETS_UP","description":"Genes up-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-1 microRNA."} {"geneset":"IKEDA_MIR1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IKEDA_MIR1_TARGETS_DN","description":"Genes down-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-1 microRNA."} {"geneset":"IKEDA_MIR133_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IKEDA_MIR133_TARGETS_UP","description":"Genes up-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-133 microRNA."} {"geneset":"IKEDA_MIR133_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IKEDA_MIR133_TARGETS_DN","description":"Genes down-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-133 microRNA."} {"geneset":"IKEDA_MIR30_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IKEDA_MIR30_TARGETS_UP","description":"Genes up-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-30 microRNA."} {"geneset":"IKEDA_MIR30_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IKEDA_MIR30_TARGETS_DN","description":"Genes down-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-30 microRNA."} {"geneset":"KUWANO_RNA_STABILIZED_BY_NO","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUWANO_RNA_STABILIZED_BY_NO","description":"Transcripts stabilized by NO [PubChem=145068] identified as up-regulated by NO [PubChem=145068] in the presence of actinomycin D [PubChemiD=2019] in IMR-90 and NIH 3T3 cells (fibroblast)."} {"geneset":"LIU_TOPBP1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_TOPBP1_TARGETS","description":"Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of TOPBP1 [GeneID=11073]."} {"geneset":"SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP","description":"Genes up-regulated in E12.5 forelimb buds with POR [GeneID=5447] knockout."} {"geneset":"SCHMIDT_POR_TARGETS_IN_LIMB_BUD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCHMIDT_POR_TARGETS_IN_LIMB_BUD_DN","description":"Genes down-regulated in E12.5 forelimb buds with POR [GeneID=5447] knockout."} {"geneset":"KATSANOU_ELAVL1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KATSANOU_ELAVL1_TARGETS_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) with ELAVL1 [GeneID=1994] knocked out."} {"geneset":"KATSANOU_ELAVL1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KATSANOU_ELAVL1_TARGETS_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) with ELAVL1 [GeneID=1994] knocked out."} {"geneset":"WANG_THOC1_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_THOC1_TARGETS_UP","description":"Genes up-regulated in testis tissue expressing hypomorphic allele of THOC1 [GeneID=9984]."} {"geneset":"WANG_THOC1_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_THOC1_TARGETS_DN","description":"Genes down-regulated in testis tissue expressing hypomorphic allele of THOC1 [GeneID=9984]."} {"geneset":"JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP","description":"Genes up-regulated in 745A cells (erythroleukemia) upon knockdown of FLI1 [GeneID=2313] by RNAi and down-regulation of SPI1 [GeneID=6688] by HMBA [PubChem=3616]."} {"geneset":"JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN","description":"Genes down-regulated in 745A cells (erythroleukemia) upon knockdown of FLI1 [GeneID=2313] by RNAi and down-regulation of SPI1 [GeneID=6688] by HMBA [PubChem=3616]."} {"geneset":"SERVITJA_ISLET_HNF1A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SERVITJA_ISLET_HNF1A_TARGETS_UP","description":"Genes up-regulated in pancreatic islets upon knockout of HNF1A [GeneID=6927]."} {"geneset":"SERVITJA_ISLET_HNF1A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SERVITJA_ISLET_HNF1A_TARGETS_DN","description":"Genes down-regulated in pancreatic islets upon knockout of HNF1A [GeneID=6927]."} {"geneset":"SERVITJA_LIVER_HNF1A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SERVITJA_LIVER_HNF1A_TARGETS_UP","description":"Genes up-regulated in liver tissue upon knockout of HNF1A [GeneID=6927]."} {"geneset":"SERVITJA_LIVER_HNF1A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SERVITJA_LIVER_HNF1A_TARGETS_DN","description":"Genes down-regulated in liver tissue upon knockout of HNF1A [GeneID=6927]."} {"geneset":"MADAN_DPPA4_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MADAN_DPPA4_TARGETS","description":"Genes differentially expressed in ES cells with DPPA4 [GeneID=55211] knockout."} {"geneset":"KOHOUTEK_CCNT1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOHOUTEK_CCNT1_TARGETS","description":"Genes down-regulated in E14 ES (embryonic stem) cells upon knockdown of CYCT1 [GeneID=904] by RNAi."} {"geneset":"KOHOUTEK_CCNT2_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KOHOUTEK_CCNT2_TARGETS","description":"Genes down-regulated in E14 ES (embryonic stem) cells upon knockdown of CYCT2 [GeneID=905] by RNAi."} {"geneset":"PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1","description":"Genes regulated in MCF7 cells (breast cancer) by expression of full-length and truncated (611-CTF) forms of ERBB2 [GeneID=2064] at both 15 h and 60 h time points."} {"geneset":"PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_3","description":"Genes regulated in MCF7 cells (breast cancer) by expression of the truncated (611-CTF) form of ERBB2 [GeneID=2064] at both 15 h and 60 h time points."} {"geneset":"PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4","description":"Genes regulated in MCF7 cells (breast cancer) by expression of the full-length and truncated (611-CTF) forms of ERBB2 [GeneID=2064] at 60 h time point."} {"geneset":"PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5","description":"Genes regulated in MCF7 cells (breast cancer) by expression of the truncated (611-CTF) form of ERBB2 [GeneID=2064] at 15 h time point."} {"geneset":"PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6","description":"Genes regulated in MCF7 cells (breast cancer) by expression of the full-length form of ERBB2 [GeneID=2064] at 60 h time point."} {"geneset":"PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7","description":"Genes regulated in MCF7 cells (breast cancer) by expression of the truncated (611-CTF) form of ERBB2 [GeneID=2064] at 60 h time point."} {"geneset":"PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2","description":"Genes up-regulated in MCF7 cells (breast cancer) more than three-fold by the truncated form 611-CTF of ERBB2 [GeneID=2064] and less than two-fold by the full-length ERBB2 [GeneID=2064]."} {"geneset":"WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_36HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_36HR","description":"Genes with promoters bound by both PPARG and RXRA [GeneID=5468, 6256] at 36 h time point of adipocyte differentiation of 3T3-L1 cells (preadipocyte)."} {"geneset":"WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_36HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_36HR","description":"Genes with promoters bound by PPARG [GeneID=5468] at 36 h time point of adipocyte differentiation of 3T3-L1 cells (preadipocyte)."} {"geneset":"WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D","description":"Genes with promoters bound by both PPARG and RXRA [GeneID=5468, 6256] at 8 day time point of adipocyte differentiation of 3T3-L1 cells (preadipocyte)."} {"geneset":"WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D","description":"Genes with promoters bound by PPARG [GeneID=5468] at 8 day time point of adipocyte differentiation of 3T3-L1 cells (preadipocyte)."} {"geneset":"WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK","description":"Genes with promoters bound by both PPARG and RXRA [GeneID=5468, 6256] at 8 (but not 0) day time point of adipocyte differentiation of 3T3-L1 cells (preadipocyte) and that were newly modified by H4K20me1."} {"geneset":"PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP","description":"Genes up-regulated in M2-10B4 cells (osteoblast) in response to phenylamil [PubChem=4755]."} {"geneset":"PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_DN","description":"Genes down-regulated in M2-10B4 cells (osteoblast) in response to phenylamil [PubChem=4755]."} {"geneset":"YANG_BCL3_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_BCL3_TARGETS_UP","description":"Genes up-regulated in neonatal cardiac myocytes upon knockdown of BCL3 [GeneID=602] by RNAi."} {"geneset":"YANG_BCL3_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YANG_BCL3_TARGETS_DN","description":"Genes down-regulated in neonatal cardiac myocytes upon knockdown of BCL3 [GeneID=602] by RNAi."} {"geneset":"LOPEZ_TRANSLATION_VIA_FN1_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LOPEZ_TRANSLATION_VIA_FN1_SIGNALING","description":"Genes translationally up-regulated in HUVEC cells (endothelium) grown on FN1 [GeneID=2335] compared to those grown on laminin 1."} {"geneset":"VERNOCHET_ADIPOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VERNOCHET_ADIPOGENESIS","description":"Genes up-regulated during adipogenic differentiation of 3T3-L1 cells (preadipocyte) and down-regulated by troglitazone [PubChem=5591]."} {"geneset":"IM_SREBF1A_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IM_SREBF1A_TARGETS","description":"Genes differentially expressed in liver tissue upon knockout of the 1a isoform of SREBF1 [GeneID=6720]."} {"geneset":"GUO_TARGETS_OF_IRS1_AND_IRS2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUO_TARGETS_OF_IRS1_AND_IRS2","description":"Transcripts dependent upon IRS1 and IRS2 [GeneID=3667, 8660] for normal expression in liver."} {"geneset":"HUANG_GATA2_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUANG_GATA2_TARGETS_UP","description":"Genes up-regulated in G1ME cells (megakaryocyte/erythroid progenitor lacking GATA1 [GeneID=2623]) upon knockdown of GATA2 [GeneID=2624] by RNAi."} {"geneset":"HUANG_GATA2_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HUANG_GATA2_TARGETS_DN","description":"Genes down-regulated in G1ME cells (megakaryocyte/erythroid progenitor lacking GATA1 [GeneID=2623]) upon knockdown of GATA2 [GeneID=2624] by RNAi."} {"geneset":"LE_NEURONAL_DIFFERENTIATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LE_NEURONAL_DIFFERENTIATION_UP","description":"Genes up-regulated during neuronal differentiation of SH-SY5Y cells (neuroblastoma) in response to stimulation by tretinoin (all-trans retinoic acid, ATRA) [PubChem=444795] and BDNF [GeneID=627]."} {"geneset":"LE_NEURONAL_DIFFERENTIATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LE_NEURONAL_DIFFERENTIATION_DN","description":"Genes down-regulated during neuronal differentiation of SH-SY5Y cells (neuroblastoma) in response to stimulation by tretinoin (all-trans retinoic acid, ATRA) [PubChem=444795] and BDNF [GeneID=627]."} {"geneset":"STEINER_ERYTHROCYTE_MEMBRANE_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STEINER_ERYTHROCYTE_MEMBRANE_GENES","description":"Major erythrocyte membrane genes."} {"geneset":"PLASARI_TGFB1_TARGETS_1HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_TGFB1_TARGETS_1HR_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) upon stimulation with TGFB1 [GeneID=7040] for 1 h."} {"geneset":"PLASARI_TGFB1_TARGETS_1HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_TGFB1_TARGETS_1HR_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) upon stimulation with TGFB1 [GeneID=7040] for 1 h."} {"geneset":"PLASARI_TGFB1_TARGETS_10HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_TGFB1_TARGETS_10HR_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) upon stimulation with TGFB1 [GeneID=7040] for 10 h."} {"geneset":"PLASARI_TGFB1_TARGETS_10HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_TGFB1_TARGETS_10HR_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) upon stimulation with TGFB1 [GeneID=7040] for 10 h."} {"geneset":"PLASARI_NFIC_TARGETS_BASAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_NFIC_TARGETS_BASAL_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblast) upon knockout of NFIC [GeneID=4782]."} {"geneset":"PLASARI_NFIC_TARGETS_BASAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_NFIC_TARGETS_BASAL_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblast) upon knockout of NFIC [GeneID=4782]."} {"geneset":"PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP","description":"Genes up-regulated after 1 h of TGFB1 [GeneID=7040] stimulation in MEF cells (embryonic fibroblast) with NFIC [GeneID=4782] knockout vs wild type MEFs."} {"geneset":"PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN","description":"Genes down-regulated after 1 h of TGFB1 [GeneID=7040] stimulation in MEF cells (embryonic fibroblast) with NFIC [GeneID=4782] knockout vs wild type MEFs."} {"geneset":"PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP","description":"Genes up-regulated after 10 h of TGFB1 [GeneID=7040] stimulation in MEF cells (embryonic fibroblast) with NFIC [GeneID=4782] knockout vs wild type MEFs."} {"geneset":"PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_DN","description":"Genes down-regulated after 10 h of TGFB1 [GeneID=7040] stimulation in MEF cells (embryonic fibroblast) with NFIC [GeneID=4782] knockout vs wild type MEFs."} {"geneset":"WANG_MLL_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WANG_MLL_TARGETS","description":"Genes requiring MLL [GeneID=4297] for H3K4me3 and expression in MEF cells (embryonic fibroblast)."} {"geneset":"SANDERSON_PPARA_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SANDERSON_PPARA_TARGETS","description":"Hepatic genes regulated by fasting or in response to WY14643 [PubChem=5694] and which require intact PPARA [GeneID=5465]."} {"geneset":"KANG_GLIS3_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KANG_GLIS3_TARGETS","description":"Genes downregulated in the postnatal day 3 pancreata with impaired function of GLIS3 [GeneID=169792]."} {"geneset":"DELACROIX_RARG_BOUND_MEF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELACROIX_RARG_BOUND_MEF","description":"Genes with DNA sequences bound by RARG [GeneID=5916] in MEF cells (embryonic fibroblast)."} {"geneset":"DELACROIX_RAR_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELACROIX_RAR_TARGETS_UP","description":"Genes bound by RARG [GeneID=5916] and up-regulated by tretinoin (all-trans retinoic acid, ATRA) [PubChem=444795] in MEF cells (embryonic fibroblast)."} {"geneset":"DELACROIX_RAR_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELACROIX_RAR_TARGETS_DN","description":"Genes bound by RARG [GeneID=5916] and down-regulated by tretinoin (all-trans retinoic acid, ATRA) [PubChem=444795] in MEF cells (embryonic fibroblast)."} {"geneset":"DELACROIX_RAR_BOUND_ES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DELACROIX_RAR_BOUND_ES","description":"Genes with DNA sequences bound by RARA and RARG [GeneID=5914, 5916] in ES cells."} {"geneset":"KRIEG_HYPOXIA_VIA_KDM3A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRIEG_HYPOXIA_VIA_KDM3A","description":"Genes dependent on KDM3A [GeneID=55818] for hypoxic induction in RCC4 cells (renal carcinoma) expressing VHL [GeneID=7428]."} {"geneset":"KRIEG_KDM3A_TARGETS_NOT_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRIEG_KDM3A_TARGETS_NOT_HYPOXIA","description":"Genes not induced under hypoxia, but dependent on KDM3A [GeneID=55818] for hypoxic expression in RCC4 cells (renal carcinoma) expressing VHL [GeneID=7428]."} {"geneset":"KRIEG_HYPOXIA_NOT_VIA_KDM3A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRIEG_HYPOXIA_NOT_VIA_KDM3A","description":"Genes induced under hypoxia independently of KDM3A [GeneID=55818] in RCC4 cells (renal carcinoma) expressing VHL [GeneID=7428]."} {"geneset":"MALIK_REPRESSED_BY_ESTROGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MALIK_REPRESSED_BY_ESTROGEN","description":"Genes consistently and robustly repressed by estradiol [PubChem=5757] in MCF7 cells (breast cancer); this reperession was prevented by fulvestrant [PubChem=3478439]."} {"geneset":"TIAN_BHLHA15_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TIAN_BHLHA15_TARGETS","description":"Genes up-regulated in both AGS and HGC-27 cells (gastric cancer) by BHLHA15 [GeneID=168620] transfection."} {"geneset":"LIU_IL13_MEMORY_MODEL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_IL13_MEMORY_MODEL_UP","description":"Genes up-regulated in BEAS-2B cells (bronchial epithelium) stimulated with IL13 [GeneID=3596] on days 1 to 3 and then rested for the next 3 days (repeated-stimulation or memory model)"} {"geneset":"LIU_IL13_MEMORY_MODEL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_IL13_MEMORY_MODEL_DN","description":"Genes down-regulated in BEAS-2B cells (bronchial epithelium) stimulated with IL13 [GeneID=3596] on days 1 to 3 and then rested for the next 3 days (repeated-stimulation or memory model)"} {"geneset":"LIU_IL13_PRIMING_MODEL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIU_IL13_PRIMING_MODEL","description":"Genes up-regulated in BEAS-2B cells (bronchial epithelium) stimulated with IL13 [GeneID=3596] on days 1 to 3, rested on days 4 and 5, and then restimulated on day 6 for 1 h before lysis (priming model)."} {"geneset":"ALFANO_MYC_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALFANO_MYC_TARGETS","description":"Genes up-regulated hT-RPE cells (immortalized retinal pigment epithelium) by MYC [GeneID=4609]."} {"geneset":"FU_INTERACT_WITH_ALKBH8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FU_INTERACT_WITH_ALKBH8","description":"Proteins identified by mass spectrometry in complexes containing ALKBH8 [GeneID=91801]."} {"geneset":"SUZUKI_CTCFL_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SUZUKI_CTCFL_TARGETS_UP","description":"Genes up-regulated in testis tissue upon knockout of CTCFL [GeneID=140690]."} {"geneset":"REICHERT_MITOSIS_LIN9_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/REICHERT_MITOSIS_LIN9_TARGETS","description":"Genes with known mitosis function that were down-regulated in MEF cells (embryonic fibroblast) upon knockout of LIN9 [GeneID=286826]."} {"geneset":"GUILLAUMOND_KLF10_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUILLAUMOND_KLF10_TARGETS_UP","description":"Genes up-regulated in the liver tissue from 10 week old male mice with KLF10 [GeneID=7071] compared to wild-type littermates."} {"geneset":"GUILLAUMOND_KLF10_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GUILLAUMOND_KLF10_TARGETS_DN","description":"Genes down-regulated in the liver tissue from 10 week old male mice with KLF10 [GeneID=7071] compared to wild-type littermates."} {"geneset":"FORTSCHEGGER_PHF8_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FORTSCHEGGER_PHF8_TARGETS_UP","description":"Genes up-regulated in HeLa cells (cervical carcinoma) upon knockdown of PHF8 [GeneID=23133] by RNAi."} {"geneset":"FORTSCHEGGER_PHF8_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FORTSCHEGGER_PHF8_TARGETS_DN","description":"Genes down-regulated in HeLa cells (cervical carcinoma) upon knockdown of PHF8 [GeneID=23133] by RNAi."} {"geneset":"BRIDEAU_IMPRINTED_GENES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRIDEAU_IMPRINTED_GENES","description":"List of genomically imprinted genes."} {"geneset":"PEDRIOLI_MIR31_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDRIOLI_MIR31_TARGETS_UP","description":"Genes up-regulated in primary LEC cells (lymphatic endothelum) upon overexpression of MIR31 [GeneID=407035]."} {"geneset":"PEDRIOLI_MIR31_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEDRIOLI_MIR31_TARGETS_DN","description":"Genes down-regulated in primary LEC cells (lymphatic endothelum) upon overexpression of MIR31 [GeneID=407035]."} {"geneset":"PHONG_TNF_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PHONG_TNF_TARGETS_UP","description":"Genes up-regulated in Calu-6 cells (lung cancer) at 1 h time point after TNF [GeneID=7124] treatment."} {"geneset":"PHONG_TNF_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PHONG_TNF_TARGETS_DN","description":"Genes down-regulated in Calu-6 cells (lung cancer) at 1 h time point after TNF [GeneID=7124] treatment."} {"geneset":"PHONG_TNF_RESPONSE_VIA_P38_COMPLETE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PHONG_TNF_RESPONSE_VIA_P38_COMPLETE","description":"Genes whose expression changes in Calu-6 cells (lung cancer) by TNF [GeneID=7124] were blocked completely by p38 inhibitor LY479754."} {"geneset":"PHONG_TNF_RESPONSE_VIA_P38_PARTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PHONG_TNF_RESPONSE_VIA_P38_PARTIAL","description":"Genes whose expression changes in Calu-6 cells (lung cancer) by TNF [GeneID=7124] were blocked partially by p38 inhibitor LY479754."} {"geneset":"PHONG_TNF_RESPONSE_NOT_VIA_P38","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PHONG_TNF_RESPONSE_NOT_VIA_P38","description":"Genes whose expression changes in Calu-6 cells (lung cancer) by TNF [GeneID=7124] were not affected by p38 inhibitor LY479754."} {"geneset":"RATTENBACHER_BOUND_BY_CELF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RATTENBACHER_BOUND_BY_CELF1","description":"Transcripts bound by CELF1 [GeneID=10658] in HeLa cells (cervical carcinoma)."} {"geneset":"KINNEY_DNMT1_METHYLATION_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KINNEY_DNMT1_METHYLATION_TARGETS","description":"Hypomethylated genes in prostate tissue from mice carrying hypomorphic alleles of DNMT1 [GeneID=1786]."} {"geneset":"ABDELMOHSEN_ELAVL4_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABDELMOHSEN_ELAVL4_TARGETS","description":"Major ELAVL4 [GeneID=1996] associated mRNAs encoding proteins with functions in neuronal physiology."} {"geneset":"ZHANG_ADIPOGENESIS_BY_BMP7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHANG_ADIPOGENESIS_BY_BMP7","description":"Genes up-regulated in C3H10T1/2 cells (mesenchyme multipotent cells) upon their differentiation to brown adipocytes in response to BMP7 [GeneID=655]."} {"geneset":"FOSTER_KDM1A_TARGETS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOSTER_KDM1A_TARGETS_UP","description":"Genes up-regulated in ES cells (embryonic stem) heterozygotic for KDM1A [GeneID=23028] loss of function mutant compared to the homozygotic loss of the gene."} {"geneset":"FOSTER_KDM1A_TARGETS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOSTER_KDM1A_TARGETS_DN","description":"Genes down-regulated in ES cells (embryonic stem) heterozygotic for KDM1A [GeneID=23028] loss of function mutant compared to the homozygotic loss of the gene."} {"geneset":"YU_BAP1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YU_BAP1_TARGETS","description":"Genes deregulated in U2OS cells (osteosarcoma) upon knockdown of BAP1 [GeneID=8314] by RNAi."} {"geneset":"RAO_BOUND_BY_SALL4_ISOFORM_A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAO_BOUND_BY_SALL4_ISOFORM_A","description":"Loci bound exclusively by SALL4 [GeneID=57167] isoform a in ES cells (embryonic stem)."} {"geneset":"RAO_BOUND_BY_SALL4_ISOFORM_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAO_BOUND_BY_SALL4_ISOFORM_B","description":"Loci bound exclusively by SALL4 [GeneID=57167] isoform b in ES cells (embryonic stem)."} {"geneset":"RAO_BOUND_BY_SALL4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAO_BOUND_BY_SALL4","description":"Loci bound by both isoforms (a and b) of SALL4 [GeneID=57167] in ES cells (embryonic stem)."} {"geneset":"VANOEVELEN_MYOGENESIS_SIN3A_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VANOEVELEN_MYOGENESIS_SIN3A_TARGETS","description":"Loci bound exclusively by SIN3A [GeneID=25942] in myotubules."} {"geneset":"BOUDOUKHA_BOUND_BY_IGF2BP2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOUDOUKHA_BOUND_BY_IGF2BP2","description":"Transcripts bound to IGF2BP2 [GeneID=10644] complexes and differentially regulated in myoblasts with IGF2BP2 [GeneID=10644] knockdown by RNAi."} {"geneset":"BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE","description":"Genes representing a co-expression network in atopic CD4 [GeneID=920] T lymphocyte responses."} {"geneset":"BOSCO_TH1_CYTOTOXIC_MODULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOSCO_TH1_CYTOTOXIC_MODULE","description":"Genes representing Th1 / cytotoxic module in sputum during asthma exacerbations."} {"geneset":"BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE","description":"Genes representing interferon-induced antiviral module in sputum during asthma exacerbations."} {"geneset":"BOSCO_EPITHELIAL_DIFFERENTIATION_MODULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BOSCO_EPITHELIAL_DIFFERENTIATION_MODULE","description":"Genes representing epithelial differentiation module in sputum during asthma exacerbations."} {"geneset":"PECE_MAMMARY_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PECE_MAMMARY_STEM_CELL_UP","description":"The '3/3 signature': genes consistently up-regulated in all three pools of normal mammary stem cells (defined by their ability to retain the dye PKH26)."} {"geneset":"PECE_MAMMARY_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PECE_MAMMARY_STEM_CELL_DN","description":"The '3/3 signature': genes consistently down-regulated in all three pools of normal mammary stem cells (defined by their ability to retain the dye PKH26)."} {"geneset":"ABRAMSON_INTERACT_WITH_AIRE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ABRAMSON_INTERACT_WITH_AIRE","description":"Proteins interacting with AIRE [GeneID=326], based on massspectroscopy analysis of co-immunoprecipitates in 293T cells (embryonic kidney)."} {"geneset":"MIZUSHIMA_AUTOPHAGOSOME_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIZUSHIMA_AUTOPHAGOSOME_FORMATION","description":"Key proteins in mammalian autophagosome formation."} {"geneset":"KUMAR_PATHOGEN_LOAD_BY_MACROPHAGES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUMAR_PATHOGEN_LOAD_BY_MACROPHAGES","description":"Genes indentified by RNAi screen as regulating infection of THP-1 cells (macrophage) with Mycobacterium tuberculosis."} {"geneset":"KUMAR_AUTOPHAGY_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KUMAR_AUTOPHAGY_NETWORK","description":"Genes defining the Mycobacterium tuberculosis strain-independent regulatory axis of the host macrophage cells."} {"geneset":"GENTLES_LEUKEMIC_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTLES_LEUKEMIC_STEM_CELL_UP","description":"Genes up-regulated in LSC (leukemic stem) cells compared to LPC (leukemia progenitor) cells from AML (acute myeloid leukemia) tumor samples."} {"geneset":"GENTLES_LEUKEMIC_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GENTLES_LEUKEMIC_STEM_CELL_DN","description":"Genes down-regulated in LSC (leukemic stem) cells compared to LPC (leukemia progenitor) cells from AML (acute myeloid leukemia) tumor samples."} {"geneset":"ROESSLER_LIVER_CANCER_METASTASIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROESSLER_LIVER_CANCER_METASTASIS_UP","description":"Genes up-regulated in liver samples containing tumor thrombi in the major branches of the portal vein at surgery (PT) compared to those from metastasis-free HCC patients (PN) at the time of surgery and at follow-up."} {"geneset":"ROESSLER_LIVER_CANCER_METASTASIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROESSLER_LIVER_CANCER_METASTASIS_DN","description":"Genes down-regulated in liver samples containing tumor thrombi in the major branches of the portal vein at surgery (PT) compared to those from metastasis-free HCC patients (PN) at the time of surgery and at follow-up."} {"geneset":"HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_UP","description":"Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive B-lineage ALL; here - genes up-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_DN","description":"Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive B-lineage ALL; here - genes down-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_UP","description":"Genes distinguishing vincristine [PubChem=5978] resistant and sensitive B-lineage ALL; here - genes up-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_DN","description":"Genes distinguishing vincristine [PubChem=5978] resistant and sensitive B-lineage ALL; here - genes down-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_ASPARAGINASE_RESISTANCE_B_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_ASPARAGINASE_RESISTANCE_B_ALL_UP","description":"Genes distinguishing asparaginase resistant and sensitive B-lineage ALL; here - genes up-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_ASPARAGINASE_RESISTANCE_B_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_ASPARAGINASE_RESISTANCE_B_ALL_DN","description":"Genes distinguishing asparaginase resistant and sensitive B-lineage ALL; here - genes down-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_DAUNORUBICIN_B_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_DAUNORUBICIN_B_ALL_UP","description":"Genes distinguishing daunorubicin [PubChem=30323] resistant and sensitive B-lineage ALL; here - genes up-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_DAUNORUBICIN_B_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_DAUNORUBICIN_B_ALL_DN","description":"Genes distinguishing daunorubicin [PubChem=30323] resistant and sensitive B-lineage ALL; here - genes down-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_UP","description":"Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive ALL (B- and T-lineage ALL); here - genes up-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_DN","description":"Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_VINCRISTINE_RESISTANCE_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_VINCRISTINE_RESISTANCE_ALL_UP","description":"Genes distinguishing vincristine [PubChem=5978] resistant and sensitive ALL (B- and T-lineage ALL); here - genes up-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_VINCRISTINE_RESISTANCE_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_VINCRISTINE_RESISTANCE_ALL_DN","description":"Genes distinguishing vincristine [PubChem=5978] resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_DAUNORUBICIN_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_DAUNORUBICIN_ALL_UP","description":"Genes distinguishing daunorubicin [PubChem=30323] resistant and sensitive ALL (B- and T-lineage ALL); here - genes up-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_DAUNORUBICIN_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_DAUNORUBICIN_ALL_DN","description":"Genes distinguishing daunorubicin [PubChem=30323] resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_ASPARAGINASE_RESISTANCE_ALL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_ASPARAGINASE_RESISTANCE_ALL_UP","description":"Genes distinguishing asparaginase resistant and sensitive ALL (B- and T-lineage ALL); here - genes up-regulated in the drug resistant samples."} {"geneset":"HOLLEMAN_ASPARAGINASE_RESISTANCE_ALL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLEMAN_ASPARAGINASE_RESISTANCE_ALL_DN","description":"Genes distinguishing asparaginase resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples."} {"geneset":"ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION","description":"Genes up-regulated in lung tissue upon LPS aspiration with mechanical ventilation (MV) compared to control (PBS aspiration without MV)."} {"geneset":"ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP","description":"Genes up-regulated during prostate cancer progression in the JOCK1 model due to inducible activation of FGFR1 [GeneID=2260] gene in prostate."} {"geneset":"ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN","description":"Genes down-regulated during prostate cancer progression in the JOCK1 model due to inducible activation of FGFR1 [GeneID=2260] gene in prostate."} {"geneset":"ANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE","description":"Invasiveness signature resulting from cancer cell/microenvironment interaction."} {"geneset":"LIM_MAMMARY_STEM_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIM_MAMMARY_STEM_CELL_UP","description":"Genes consistently up-regulated in mammary stem cells both in mouse and human species."} {"geneset":"LIM_MAMMARY_STEM_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIM_MAMMARY_STEM_CELL_DN","description":"Genes consistently down-regulated in mammary stem cells both in mouse and human species."} {"geneset":"LIM_MAMMARY_LUMINAL_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIM_MAMMARY_LUMINAL_PROGENITOR_UP","description":"Genes consistently up-regulated in mammary luminal progenitor cells both in mouse and human species."} {"geneset":"LIM_MAMMARY_LUMINAL_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIM_MAMMARY_LUMINAL_PROGENITOR_DN","description":"Genes consistently down-regulated in mammary luminal progenitor cells both in mouse and human species."} {"geneset":"LIM_MAMMARY_LUMINAL_MATURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIM_MAMMARY_LUMINAL_MATURE_UP","description":"Genes consistently up-regulated in mature mammary luminal cells both in mouse and human species."} {"geneset":"LIM_MAMMARY_LUMINAL_MATURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LIM_MAMMARY_LUMINAL_MATURE_DN","description":"Genes consistently down-regulated in mature mammary luminal cells both in mouse and human species."} {"geneset":"DURAND_STROMA_S_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DURAND_STROMA_S_UP","description":"Genes up-regulated in the HSC supportive stromal cell lines."} {"geneset":"DURAND_STROMA_NS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DURAND_STROMA_NS_UP","description":"Genes up-regulated in the HSC non-supportive stromal cell lines."} {"geneset":"SMIRNOV_RESPONSE_TO_IR_2HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMIRNOV_RESPONSE_TO_IR_2HR_UP","description":"Genes up-regulated in B lymphocytes at 2 h after exprosure to 10 Gy dose of ionizing radiation."} {"geneset":"SMIRNOV_RESPONSE_TO_IR_2HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMIRNOV_RESPONSE_TO_IR_2HR_DN","description":"Genes down-regulated in B lymphocytes at 2 h after exprosure to 10 Gy dose of ionizing radiation."} {"geneset":"SMIRNOV_RESPONSE_TO_IR_6HR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMIRNOV_RESPONSE_TO_IR_6HR_UP","description":"Genes up-regulated in B lymphocytes at 6 h after exprosure to 10 Gy dose of ionizing radiation."} {"geneset":"SMIRNOV_RESPONSE_TO_IR_6HR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMIRNOV_RESPONSE_TO_IR_6HR_DN","description":"Genes down-regulated in B lymphocytes at 6 h after exprosure to 10 Gy dose of ionizing radiation."} {"geneset":"GHANDHI_DIRECT_IRRADIATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GHANDHI_DIRECT_IRRADIATION_UP","description":"Genes significantly (FDR < 10%) up-regulated in IMR-90 cells (fibroblast) in response to direct irradiation."} {"geneset":"GHANDHI_DIRECT_IRRADIATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GHANDHI_DIRECT_IRRADIATION_DN","description":"Genes significantly (FDR < 10%) down-regulated in IMR-90 cells (fibroblast) in response to direct irradiation."} {"geneset":"GHANDHI_BYSTANDER_IRRADIATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GHANDHI_BYSTANDER_IRRADIATION_UP","description":"Genes significantly (FDR < 10%) up-regulated in IMR-90 cells (fibroblast) in response to bystander irradiation."} {"geneset":"GHANDHI_BYSTANDER_IRRADIATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GHANDHI_BYSTANDER_IRRADIATION_DN","description":"Genes significantly (FDR < 10%) down-regulated in IMR-90 cells (fibroblast) in response to bystander irradiation."} {"geneset":"WARTERS_RESPONSE_TO_IR_SKIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WARTERS_RESPONSE_TO_IR_SKIN","description":"Genes displaying an ionizing radiation response in the human skin cell samples."} {"geneset":"WARTERS_IR_RESPONSE_5GY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WARTERS_IR_RESPONSE_5GY","description":"Genes up-regulated in the human skin cells at 4 h after exprosure to 5 Gy dose of ionizing radiation."} {"geneset":"ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_2HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_2HR","description":"Cell cycle genes significantly (p =< 0.05) changed in fibroblast cells at 2 h after exposure to ionizing radiation."} {"geneset":"ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR","description":"Cell cycle genes significantly (p =< 0.05) changed in fibroblast cells at 6 h after exposure to ionizing radiation."} {"geneset":"ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR","description":"Cell cycle genes significantly (p =< 0.05) changed in fibroblast cells at 24 h after exposure to ionizing radiation."} {"geneset":"ZWANG_EGF_PERSISTENTLY_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_EGF_PERSISTENTLY_UP","description":"Genes persistently induced by EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF","description":"Class I of genes transiently induced by EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF","description":"Class II of genes transiently induced by EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF","description":"Class III of genes transiently induced by EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_DOWN_BY_2ND_EGF_PULSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_DOWN_BY_2ND_EGF_PULSE","description":"Genes down-regulated by second pulse of EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY","description":"Genes transiently induced only by the second pulse of EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY","description":"Genes transiently induced only by the first pulse of EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_EGF_INTERVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_EGF_INTERVAL_UP","description":"Genes induced in the time interval between two pulses of EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_EGF_INTERVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_EGF_INTERVAL_DN","description":"Genes repressed in the time interval between two pulses of EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"ZWANG_EGF_PERSISTENTLY_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZWANG_EGF_PERSISTENTLY_DN","description":"Genes persistently repressed by EGF [GeneID =1950] in 184A1 cells (mammary epithelium)."} {"geneset":"CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_UP","description":"Genes up-regulated in type 1 (soleus) vs type 2B (EDL) myofibers."} {"geneset":"CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_DN","description":"Genes down-regulated in type 2B (EDL) vs type 1 (soleus) myofibers."} {"geneset":"HORTON_SREBF_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HORTON_SREBF_TARGETS","description":"Genes up-regulated in liver from mice transgenic for SREBF1 or SREBF2 [GeneID = 6720, 6721] and down-regulated in mice lacking SCAP [GeneID=22937]."} {"geneset":"HECKER_IFNB1_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HECKER_IFNB1_TARGETS","description":"Genes transcriptionally modulated in the blood of multiple sclerosis patients in response to subcutaneous treatment with recombinant IFNB1 [GeneID = 3456]."} {"geneset":"NABA_COLLAGENS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_COLLAGENS","description":"Genes encoding collagen proteins"} {"geneset":"NABA_ECM_GLYCOPROTEINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_ECM_GLYCOPROTEINS","description":"Genes encoding structural ECM glycoproteins"} {"geneset":"NABA_ECM_REGULATORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_ECM_REGULATORS","description":"Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix"} {"geneset":"NABA_ECM_AFFILIATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_ECM_AFFILIATED","description":"Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins"} {"geneset":"NABA_PROTEOGLYCANS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_PROTEOGLYCANS","description":"Genes encoding proteoglycans"} {"geneset":"NABA_SECRETED_FACTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_SECRETED_FACTORS","description":"Genes encoding secreted soluble factors"} {"geneset":"NABA_CORE_MATRISOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_CORE_MATRISOME","description":"Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans"} {"geneset":"NABA_MATRISOME_ASSOCIATED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_MATRISOME_ASSOCIATED","description":"Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors"} {"geneset":"NABA_BASEMENT_MEMBRANES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_BASEMENT_MEMBRANES","description":"Genes encoding structural components of basement membranes"} {"geneset":"NABA_MATRISOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NABA_MATRISOME","description":"Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins"} {"geneset":"FARMER_BREAST_CANCER_CLUSTER_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_CLUSTER_6","description":"Cluster 6: selected luminal genes clustered together across breast cancer samples."} {"geneset":"FARMER_BREAST_CANCER_CLUSTER_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_CLUSTER_5","description":"Cluster 5: selected 17q21_23 amplicon genes clustered together across breast cancer samples."} {"geneset":"FARMER_BREAST_CANCER_CLUSTER_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_CLUSTER_4","description":"Cluster 4: selected stromal genes clustered together across breast cancer samples."} {"geneset":"FARMER_BREAST_CANCER_CLUSTER_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FARMER_BREAST_CANCER_CLUSTER_3","description":"Cluster 3: selected apocrine, basal and hypoxia genes clustered together across breast cancer samples."} {"geneset":"EPPERT_LSC_R","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EPPERT_LSC_R","description":"Genes up-regulated in functionally defined leukemic stem cells (LSC) from acute myeloid leukemia (AML) patients."} {"geneset":"EPPERT_HSC_R","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EPPERT_HSC_R","description":"Genes up-regulated in human hematopoietic stem cell (HSC) enriched populations compared to committed progenitors and mature cells."} {"geneset":"EPPERT_PROGENITOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EPPERT_PROGENITOR","description":"Genes up-regulated in human hematopoietic lineage committed progenitor cells versus hematopoietic stem cells (HSC) and mature cells."} {"geneset":"EPPERT_CE_HSC_LSC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EPPERT_CE_HSC_LSC","description":"Shared human hematopoietic stem cell (HSC) and acute myeloid leukemia (AML) stem cell (LSC) genes: HSC genes that are highly expressed in LSC versus other leukemic cells."} {"geneset":"QUINTENS_EMBRYONIC_BRAIN_RESPONSE_TO_IR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/QUINTENS_EMBRYONIC_BRAIN_RESPONSE_TO_IR","description":"Genes up-regulated in the mouse embryonic brain or immature neurons at 2 h or 6 h, respectively after exposure to 1 Gy dose of ionizing radiation."} {"geneset":"MACAEVA_PBMC_RESPONSE_TO_IR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MACAEVA_PBMC_RESPONSE_TO_IR","description":"Genes up-regulated in human peripheral blood mononuclear cells (PBMC) at 8 h after exposure to 0.1 and 1.0 Gy dose of ionizing radiation."} {"geneset":"FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS","description":"Genes directly bound and regulated by TP53[GeneID=7157]."} {"geneset":"FISCHER_G1_S_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FISCHER_G1_S_CELL_CYCLE","description":"Cell cycle genes with peak expression in G1/S check point."} {"geneset":"FISCHER_G2_M_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FISCHER_G2_M_CELL_CYCLE","description":"Cell cycle genes with peak expression in G2/M check point."} {"geneset":"FISCHER_DREAM_TARGETS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FISCHER_DREAM_TARGETS","description":"Target genes of the DREAM complex."} {"geneset":"GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS","description":"Expressed genes (FPKM>1) associated with high-confidence PAX3-FOXO1 sites with enhancers in primary tumors and cell lines, restricted to those within topological domain boundaries"} {"geneset":"GRYDER_PAX3FOXO1_TOP_ENHANCERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRYDER_PAX3FOXO1_TOP_ENHANCERS","description":"Expressed genes (FPKM>1) associated with super-high-confidence PAX3-FOXO1 sites with highly-recurrent enhancers in primary tumors and cell lines, restricted to those within topological domain boundaries"} {"geneset":"GRYDER_PAX3FOXO1_ENHANCERS_KO_DOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRYDER_PAX3FOXO1_ENHANCERS_KO_DOWN","description":"Expressed genes (FPKM>1) associated with high-confidence PAX3-FOXO1 sites with enhancers in primary tumors and cell lines, restricted to those within topological domain boundaries, which are downregulated by delta log2(FPKM) < -0.2"} {"geneset":"ANDERSEN_CHOLANGIOCARCINOMA_CLASS2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ANDERSEN_CHOLANGIOCARCINOMA_CLASS2","description":"Genes overexpressed in cholangiocarcinoma class 2 associated with poor prognosis."} {"geneset":"ANDERSEN_CHOLANGIOCARCINOMA_CLASS1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ANDERSEN_CHOLANGIOCARCINOMA_CLASS1","description":"Genes overexpressed in cholangiocarcinoma class 1 associated with good prognosis"} {"geneset":"OISHI_CHOLANGIOMA_STEM_CELL_LIKE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OISHI_CHOLANGIOMA_STEM_CELL_LIKE_UP","description":"Genes over-expressed in stem cell-like cholangiocellular carcinoma."} {"geneset":"OISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN","description":"Genes under-expressed in stem cell-like cholangiocellular carcinoma"} {"geneset":"VILLANUEVA_LIVER_CANCER_KRT19_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VILLANUEVA_LIVER_CANCER_KRT19_UP","description":"Genes over-expressed in KRT19-positive [GeneID=3880] hepatocellular carcinoma (HCC)."} {"geneset":"VILLANUEVA_LIVER_CANCER_KRT19_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VILLANUEVA_LIVER_CANCER_KRT19_DN","description":"Genes under-expressed in KRT19-positive [GeneID=3880] hepatocellular carcinoma (HCC)."} {"geneset":"MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_UP","description":"Genes over-expressed in hepatocellular carcinoma (HCC) with vascular invasion."} {"geneset":"MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_DN","description":"Genes under-expressed in hepatocellular carcinoma (HCC) with vascular invasion."} {"geneset":"ANDERSEN_LIVER_CANCER_KRT19_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ANDERSEN_LIVER_CANCER_KRT19_UP","description":"Genes over-expressed in KRT19-positive [GeneID=3880] hepatocellular carcinoma."} {"geneset":"ANDERSEN_LIVER_CANCER_KRT19_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ANDERSEN_LIVER_CANCER_KRT19_DN","description":"Genes under-expressed in KRT19-positive [GeneID=3880] hepatocellular carcinoma."} {"geneset":"KIM_LIVER_CANCER_POOR_SURVIVAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_LIVER_CANCER_POOR_SURVIVAL_UP","description":"Genes over-expressed in hepatocellular carcinoma (HCC) with poor survival"} {"geneset":"KIM_LIVER_CANCER_POOR_SURVIVAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KIM_LIVER_CANCER_POOR_SURVIVAL_DN","description":"Genes under-expressed in hepatocellular carcinoma (HCC) with poor survival"} {"geneset":"HOLLERN_ADENOMYOEPITHELIAL_BREAST_TUMOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_ADENOMYOEPITHELIAL_BREAST_TUMOR","description":"Genes that have high expression in mammary tumors of adenomyoepithelial histology."} {"geneset":"HOLLERN_EMT_BREAST_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_EMT_BREAST_TUMOR_UP","description":"Genes that are highly expressed in mammary tumors of epithelial-mesenchymal transition (EMT) histology."} {"geneset":"HOLLERN_EMT_BREAST_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_EMT_BREAST_TUMOR_DN","description":"Genes that that have low expression in mammary tumors of epithelial-mesenchymal transition (EMT) histology."} {"geneset":"HOLLERN_SQUAMOUS_BREAST_TUMOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_SQUAMOUS_BREAST_TUMOR","description":"Genes that have high expression in mammary tumors of squamous epithelium histology."} {"geneset":"HOLLERN_PAPILLARY_BREAST_TUMOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_PAPILLARY_BREAST_TUMOR","description":"Genes that have high expression in paplillary mammary tumors."} {"geneset":"HOLLERN_MICROACINAR_BREAST_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_MICROACINAR_BREAST_TUMOR_UP","description":"Genes that have high expression in mammary tumors of microacinar histology."} {"geneset":"HOLLERN_MICROACINAR_BREAST_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_MICROACINAR_BREAST_TUMOR_DN","description":"Genes that have low expression in mammary tumors of microacinar histology."} {"geneset":"HOLLERN_SOLID_NODULAR_BREAST_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_SOLID_NODULAR_BREAST_TUMOR_UP","description":"Genes that have high expression in mammary tumors of solid nodular histology."} {"geneset":"HOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN","description":"Genes that have low expression in mammary tumors of solid nodular histology."} {"geneset":"FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN","description":"Genes down-regulated in basal radial glia (bRG) relative to apical radial glia (aRG), and up-regulated in both aRG and bRG relative to neurons."} {"geneset":"FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP","description":"Genes up-regulated in basal radial glia (bRG) relative to apical radial glia (aRG), and up-regulated in both aRG and bRG relative to neurons."} {"geneset":"FLORIO_HUMAN_NEOCORTEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FLORIO_HUMAN_NEOCORTEX","description":"Human-specific genes up-regulated in basal radial glia (bRG) relative to apical radial glia (aRG), and up-regulated in both aRG and bRG relative to neurons."} {"geneset":"AAANWWTGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAANWWTGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M144 AAANWWTGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AAAYRNCTG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAAYRNCTG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M77 AAAYRNCTG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"MYOD_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYOD_01","description":"Genes having at least one occurence of the transcription factor binding site V$MYOD_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E47_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E47_01","description":"Genes having at least one occurence of the transcription factor binding site V$E47_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CMYB_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CMYB_01","description":"Genes having at least one occurence of the transcription factor binding site V$CMYB_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP4_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AACTTT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AACTTT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M17 AACTTT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"MEF2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEF2_01","description":"Genes having at least one occurence of the transcription factor binding site V$MEF2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ELK1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELK1_01","description":"Genes having at least one occurence of the transcription factor binding site V$ELK1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$SP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EVI1_06","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EVI1_06","description":"Genes having at least one occurence of the transcription factor binding site V$EVI1_06 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ATF_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF_01","description":"Genes having at least one occurence of the transcription factor binding site V$ATF_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HOX13_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOX13_01","description":"Genes having at least one occurence of the transcription factor binding site V$HOX13_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ELK1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELK1_02","description":"Genes having at least one occurence of the transcription factor binding site V$ELK1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"RSRFC4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RSRFC4_01","description":"Genes having at least one occurence of the transcription factor binding site V$RSRFC4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CETS1P54_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CETS1P54_01","description":"Genes having at least one occurence of the transcription factor binding site V$CETS1P54_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AACWWCAANK_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AACWWCAANK_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M108 AACWWCAANK in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"P300_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/P300_01","description":"Genes having at least one occurence of the transcription factor binding site V$P300_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFE2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFE2_01","description":"Genes having at least one occurence of the transcription factor binding site V$NFE2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREB_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREB_01","description":"Genes having at least one occurence of the transcription factor binding site V$CREB_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREBP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREBP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$CREBP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREBP1CJUN_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREBP1CJUN_01","description":"Genes having at least one occurence of the transcription factor binding site V$CREBP1CJUN_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SOX5_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SOX5_01","description":"Genes having at least one occurence of the transcription factor binding site V$SOX5_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E4BP4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E4BP4_01","description":"Genes having at least one occurence of the transcription factor binding site V$E4BP4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_02","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFKAPPAB65_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFKAPPAB65_01","description":"Genes having at least one occurence of the transcription factor binding site V$NFKAPPAB65_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREL_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREL_01","description":"Genes having at least one occurence of the transcription factor binding site V$CREL_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AACYNNNNTTCCS_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AACYNNNNTTCCS_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M113 AACYNNNNTTCCS in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"NFKAPPAB_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFKAPPAB_01","description":"Genes having at least one occurence of the transcription factor binding site V$NFKAPPAB_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NMYC_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NMYC_01","description":"Genes having at least one occurence of the transcription factor binding site V$NMYC_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYOGNF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYOGNF1_01","description":"Genes having at least one occurence of the transcription factor binding site V$MYOGNF1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"COMP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COMP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$COMP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HEN1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEN1_02","description":"Genes having at least one occurence of the transcription factor binding site V$HEN1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"YY1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YY1_01","description":"Genes having at least one occurence of the transcription factor binding site V$YY1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IRF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IRF1_01","description":"Genes having at least one occurence of the transcription factor binding site V$IRF1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IRF2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IRF2_01","description":"Genes having at least one occurence of the transcription factor binding site V$IRF2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TAL1BETAE47_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAL1BETAE47_01","description":"Genes having at least one occurence of the transcription factor binding site V$TAL1BETAE47_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TAL1ALPHAE47_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAL1ALPHAE47_01","description":"Genes having at least one occurence of the transcription factor binding site V$TAL1ALPHAE47_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AAGWWRNYGGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAGWWRNYGGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M63 AAGWWRNYGGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"HEN1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEN1_01","description":"Genes having at least one occurence of the transcription factor binding site V$HEN1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"YY1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YY1_02","description":"Genes having at least one occurence of the transcription factor binding site V$YY1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TAL1BETAITF2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAL1BETAITF2_01","description":"Genes having at least one occurence of the transcription factor binding site V$TAL1BETAITF2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E47_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E47_02","description":"Genes having at least one occurence of the transcription factor binding site V$E47_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CP2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CP2_01","description":"Genes having at least one occurence of the transcription factor binding site V$CP2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA1_01","description":"Genes having at least one occurence of the transcription factor binding site V$GATA1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA2_01","description":"Genes having at least one occurence of the transcription factor binding site V$GATA2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA3_01","description":"Genes having at least one occurence of the transcription factor binding site V$GATA3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EVI1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EVI1_01","description":"Genes having at least one occurence of the transcription factor binding site V$EVI1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EVI1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EVI1_02","description":"Genes having at least one occurence of the transcription factor binding site V$EVI1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ACAWNRNSRCGG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACAWNRNSRCGG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M103 ACAWNRNSRCGG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"EVI1_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EVI1_03","description":"Genes having at least one occurence of the transcription factor binding site V$EVI1_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EVI1_04","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EVI1_04","description":"Genes having at least one occurence of the transcription factor binding site V$EVI1_04 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EVI1_05","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EVI1_05","description":"Genes having at least one occurence of the transcription factor binding site V$EVI1_05 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MZF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MZF1_01","description":"Genes having at least one occurence of the transcription factor binding site V$MZF1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MZF1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MZF1_02","description":"Genes having at least one occurence of the transcription factor binding site V$MZF1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ZID_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZID_01","description":"Genes having at least one occurence of the transcription factor binding site V$ZID_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IK1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IK1_01","description":"Genes having at least one occurence of the transcription factor binding site V$IK1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IK2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IK2_01","description":"Genes having at least one occurence of the transcription factor binding site V$IK2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IK3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IK3_01","description":"Genes having at least one occurence of the transcription factor binding site V$IK3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CDP_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CDP_01","description":"Genes having at least one occurence of the transcription factor binding site V$CDP_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ACAWYAAAG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACAWYAAAG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M142 ACAWYAAAG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"PBX1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PBX1_01","description":"Genes having at least one occurence of the transcription factor binding site V$PBX1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX6_01","description":"Genes having at least one occurence of the transcription factor binding site V$PAX6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX2_01","description":"Genes having at least one occurence of the transcription factor binding site V$PAX2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"S8_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/S8_01","description":"Genes having at least one occurence of the transcription factor binding site V$S8_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CDP_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CDP_02","description":"Genes having at least one occurence of the transcription factor binding site V$CDP_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CDPCR1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CDPCR1_01","description":"Genes having at least one occurence of the transcription factor binding site V$CDPCR1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CDPCR3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CDPCR3_01","description":"Genes having at least one occurence of the transcription factor binding site V$CDPCR3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CDPCR3HD_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CDPCR3HD_01","description":"Genes having at least one occurence of the transcription factor binding site V$CDPCR3HD_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NRF2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NRF2_01","description":"Genes having at least one occurence of the transcription factor binding site V$NRF2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBPB_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBPB_01","description":"Genes having at least one occurence of the transcription factor binding site V$CEBPB_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ACCTGTTG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACCTGTTG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M57 ACCTGTTG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CREB_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREB_02","description":"Genes having at least one occurence of the transcription factor binding site V$CREB_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TAXCREB_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAXCREB_01","description":"Genes having at least one occurence of the transcription factor binding site V$TAXCREB_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TAXCREB_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAXCREB_02","description":"Genes having at least one occurence of the transcription factor binding site V$TAXCREB_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBPA_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBPA_01","description":"Genes having at least one occurence of the transcription factor binding site V$CEBPA_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBPB_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBPB_02","description":"Genes having at least one occurence of the transcription factor binding site V$CEBPB_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYCMAX_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYCMAX_01","description":"Genes having at least one occurence of the transcription factor binding site V$MYCMAX_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MAX_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAX_01","description":"Genes having at least one occurence of the transcription factor binding site V$MAX_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"USF_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/USF_01","description":"Genes having at least one occurence of the transcription factor binding site V$USF_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"USF_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/USF_02","description":"Genes having at least one occurence of the transcription factor binding site V$USF_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYCMAX_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYCMAX_02","description":"Genes having at least one occurence of the transcription factor binding site V$MYCMAX_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ACTAYRNNNCCCR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTAYRNNNCCCR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M4 ACTAYRNNNCCCR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"PBX1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PBX1_02","description":"Genes having at least one occurence of the transcription factor binding site V$PBX1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA1_02","description":"Genes having at least one occurence of the transcription factor binding site V$GATA1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA1_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA1_03","description":"Genes having at least one occurence of the transcription factor binding site V$GATA1_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA1_04","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA1_04","description":"Genes having at least one occurence of the transcription factor binding site V$GATA1_04 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HFH1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HFH1_01","description":"Genes having at least one occurence of the transcription factor binding site V$HFH1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOXD3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXD3_01","description":"Genes having at least one occurence of the transcription factor binding site V$FOXD3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF3B_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF3B_01","description":"Genes having at least one occurence of the transcription factor binding site V$HNF3B_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF1_01","description":"Genes having at least one occurence of the transcription factor binding site V$HNF1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TST1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TST1_01","description":"Genes having at least one occurence of the transcription factor binding site V$TST1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF4_01","description":"Genes having at least one occurence of the transcription factor binding site V$HNF4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ACTWSNACTNY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTWSNACTNY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M105 ACTWSNACTNY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"OCT1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_01","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OCT1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_02","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OCT1_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_03","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OCT1_04","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_04","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_04 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AHR_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AHR_01","description":"Genes having at least one occurence of the transcription factor binding site V$AHR_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LYF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LYF1_01","description":"Genes having at least one occurence of the transcription factor binding site V$LYF1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX5_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX5_01","description":"Genes having at least one occurence of the transcription factor binding site V$PAX5_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX5_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX5_02","description":"Genes having at least one occurence of the transcription factor binding site V$PAX5_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"BRN2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRN2_01","description":"Genes having at least one occurence of the transcription factor binding site V$BRN2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HSF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HSF1_01","description":"Genes having at least one occurence of the transcription factor binding site V$HSF1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AGCYRWTTC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGCYRWTTC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M135 AGCYRWTTC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"HSF2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HSF2_01","description":"Genes having at least one occurence of the transcription factor binding site V$HSF2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SRY_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRY_01","description":"Genes having at least one occurence of the transcription factor binding site V$SRY_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SRF_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRF_01","description":"Genes having at least one occurence of the transcription factor binding site V$SRF_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ARP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ARP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$ARP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"RORA1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RORA1_01","description":"Genes having at least one occurence of the transcription factor binding site V$RORA1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"RORA2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RORA2_01","description":"Genes having at least one occurence of the transcription factor binding site V$RORA2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"COUP_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COUP_01","description":"Genes having at least one occurence of the transcription factor binding site V$COUP_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBP_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBP_01","description":"Genes having at least one occurence of the transcription factor binding site V$CEBP_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SRY_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRY_02","description":"Genes having at least one occurence of the transcription factor binding site V$SRY_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OCT1_05","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_05","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_05 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ARGGGTTAA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ARGGGTTAA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M65 ARGGGTTAA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"OCT1_06","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_06","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_06 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP1FJ_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1FJ_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$AP1FJ_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP1_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$AP1_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AP1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP4_Q5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP4_Q5","description":"Genes having at least one occurence of the transcription factor binding site V$AP4_Q5 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP4_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP4_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AP4_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREB_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREB_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$CREB_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREB_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREB_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$CREB_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREBP1_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREBP1_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$CREBP1_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYB_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYB_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$MYB_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ATCMNTCCGY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATCMNTCCGY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M99 ATCMNTCCGY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"MYOD_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYOD_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$MYOD_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFY_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFY_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$NFY_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SRF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRF_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$SRF_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"USF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/USF_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$USF_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP1_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$AP1_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP2_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP2_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AP2_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBP_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBP_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$CEBP_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ER_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ER_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$ER_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GR_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GR_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$GR_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$NF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ATGGYGGA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGGYGGA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M102 ATGGYGGA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"NFKB_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFKB_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$NFKB_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OCT1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SP1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SP1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$SP1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP1_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1_C","description":"Genes having at least one occurence of the transcription factor binding site V$AP1_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBP_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBP_C","description":"Genes having at least one occurence of the transcription factor binding site V$CEBP_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA_C","description":"Genes having at least one occurence of the transcription factor binding site V$GATA_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GRE_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GRE_C","description":"Genes having at least one occurence of the transcription factor binding site V$GRE_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF1_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF1_C","description":"Genes having at least one occurence of the transcription factor binding site V$HNF1_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFKB_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFKB_C","description":"Genes having at least one occurence of the transcription factor binding site V$NFKB_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFY_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFY_C","description":"Genes having at least one occurence of the transcription factor binding site V$NFY_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CAGNWMCNNNGAC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGNWMCNNNGAC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M143 CAGNWMCNNNGAC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"OCT_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT_C","description":"Genes having at least one occurence of the transcription factor binding site V$OCT_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SEF1_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SEF1_C","description":"Genes having at least one occurence of the transcription factor binding site V$SEF1_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SRF_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRF_C","description":"Genes having at least one occurence of the transcription factor binding site V$SRF_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TATA_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TATA_C","description":"Genes having at least one occurence of the transcription factor binding site V$TATA_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"USF_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/USF_C","description":"Genes having at least one occurence of the transcription factor binding site V$USF_C (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SREBP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SREBP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$SREBP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SREBP1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SREBP1_02","description":"Genes having at least one occurence of the transcription factor binding site V$SREBP1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HAND1E47_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HAND1E47_01","description":"Genes having at least one occurence of the transcription factor binding site V$HAND1E47_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT_01","description":"Genes having at least one occurence of the transcription factor binding site V$STAT_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT1_01","description":"Genes having at least one occurence of the transcription factor binding site V$STAT1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CAGNYGKNAAA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGNYGKNAAA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M160 CAGNYGKNAAA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"STAT3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT3_01","description":"Genes having at least one occurence of the transcription factor binding site V$STAT3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MEF2_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEF2_02","description":"Genes having at least one occurence of the transcription factor binding site V$MEF2_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MEF2_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEF2_03","description":"Genes having at least one occurence of the transcription factor binding site V$MEF2_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MEF2_04","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEF2_04","description":"Genes having at least one occurence of the transcription factor binding site V$MEF2_04 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AHRARNT_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AHRARNT_01","description":"Genes having at least one occurence of the transcription factor binding site V$AHRARNT_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ARNT_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ARNT_01","description":"Genes having at least one occurence of the transcription factor binding site V$ARNT_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AHRARNT_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AHRARNT_02","description":"Genes having at least one occurence of the transcription factor binding site V$AHRARNT_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NKX25_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NKX25_01","description":"Genes having at least one occurence of the transcription factor binding site V$NKX25_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NKX25_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NKX25_02","description":"Genes having at least one occurence of the transcription factor binding site V$NKX25_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PPARA_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PPARA_01","description":"Genes having at least one occurence of the transcription factor binding site V$PPARA_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CATRRAGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CATRRAGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M134 CATRRAGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"EGR1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EGR1_01","description":"Genes having at least one occurence of the transcription factor binding site V$EGR1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NGFIC_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NGFIC_01","description":"Genes having at least one occurence of the transcription factor binding site V$NGFIC_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EGR3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EGR3_01","description":"Genes having at least one occurence of the transcription factor binding site V$EGR3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EGR2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EGR2_01","description":"Genes having at least one occurence of the transcription factor binding site V$EGR2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OCT1_07","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_07","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_07 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CHOP_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHOP_01","description":"Genes having at least one occurence of the transcription factor binding site V$CHOP_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GFI1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GFI1_01","description":"Genes having at least one occurence of the transcription factor binding site V$GFI1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"XBP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/XBP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$XBP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TATA_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TATA_01","description":"Genes having at least one occurence of the transcription factor binding site V$TATA_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NRSF_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NRSF_01","description":"Genes having at least one occurence of the transcription factor binding site V$NRSF_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CCAATNNSNNNGCG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCAATNNSNNNGCG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M104 CCAATNNSNNNGCG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"RREB1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RREB1_01","description":"Genes having at least one occurence of the transcription factor binding site V$RREB1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ISRE_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ISRE_01","description":"Genes having at least one occurence of the transcription factor binding site V$ISRE_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HLF_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HLF_01","description":"Genes having at least one occurence of the transcription factor binding site V$HLF_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OLF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OLF1_01","description":"Genes having at least one occurence of the transcription factor binding site V$OLF1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AML1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AML1_01","description":"Genes having at least one occurence of the transcription factor binding site V$AML1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"P53_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/P53_02","description":"Genes having at least one occurence of the transcription factor binding site V$P53_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LMO2COM_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LMO2COM_01","description":"Genes having at least one occurence of the transcription factor binding site V$LMO2COM_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LMO2COM_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LMO2COM_02","description":"Genes having at least one occurence of the transcription factor binding site V$LMO2COM_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MIF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MIF1_01","description":"Genes having at least one occurence of the transcription factor binding site V$MIF1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"RFX1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RFX1_01","description":"Genes having at least one occurence of the transcription factor binding site V$RFX1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CCANNAGRKGGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCANNAGRKGGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M45 CCANNAGRKGGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"RFX1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RFX1_02","description":"Genes having at least one occurence of the transcription factor binding site V$RFX1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TCF11MAFG_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCF11MAFG_01","description":"Genes having at least one occurence of the transcription factor binding site V$TCF11MAFG_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TCF11_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCF11_01","description":"Genes having at least one occurence of the transcription factor binding site V$TCF11_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFY_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFY_01","description":"Genes having at least one occurence of the transcription factor binding site V$NFY_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HFH3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HFH3_01","description":"Genes having at least one occurence of the transcription factor binding site V$HFH3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FREAC2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FREAC2_01","description":"Genes having at least one occurence of the transcription factor binding site V$FREAC2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FREAC3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FREAC3_01","description":"Genes having at least one occurence of the transcription factor binding site V$FREAC3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FREAC4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FREAC4_01","description":"Genes having at least one occurence of the transcription factor binding site V$FREAC4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FREAC7_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FREAC7_01","description":"Genes having at least one occurence of the transcription factor binding site V$FREAC7_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HFH8_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HFH8_01","description":"Genes having at least one occurence of the transcription factor binding site V$HFH8_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CCAWNWWNNNGGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCAWNWWNNNGGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M165 CCAWNWWNNNGGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"NFAT_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFAT_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$NFAT_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYCMAX_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYCMAX_B","description":"Genes having at least one occurence of the transcription factor binding site V$MYCMAX_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX3_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX3_B","description":"Genes having at least one occurence of the transcription factor binding site V$PAX3_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX8_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX8_B","description":"Genes having at least one occurence of the transcription factor binding site V$PAX8_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"WHN_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WHN_B","description":"Genes having at least one occurence of the transcription factor binding site V$WHN_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ZF5_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZF5_B","description":"Genes having at least one occurence of the transcription factor binding site V$ZF5_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ATF_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF_B","description":"Genes having at least one occurence of the transcription factor binding site V$ATF_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ETS1_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ETS1_B","description":"Genes having at least one occurence of the transcription factor binding site V$ETS1_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ETS2_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ETS2_B","description":"Genes having at least one occurence of the transcription factor binding site V$ETS2_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GABP_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GABP_B","description":"Genes having at least one occurence of the transcription factor binding site V$GABP_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CCAWYNNGAAR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCAWYNNGAAR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M124 CCAWYNNGAAR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"OCT1_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_B","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA1_05","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA1_05","description":"Genes having at least one occurence of the transcription factor binding site V$GATA1_05 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX3_01","description":"Genes having at least one occurence of the transcription factor binding site V$PAX3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX4_01","description":"Genes having at least one occurence of the transcription factor binding site V$PAX4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX4_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX4_02","description":"Genes having at least one occurence of the transcription factor binding site V$PAX4_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX4_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX4_03","description":"Genes having at least one occurence of the transcription factor binding site V$PAX4_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX4_04","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX4_04","description":"Genes having at least one occurence of the transcription factor binding site V$PAX4_04 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MSX1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MSX1_01","description":"Genes having at least one occurence of the transcription factor binding site V$MSX1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HOXA3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOXA3_01","description":"Genes having at least one occurence of the transcription factor binding site V$HOXA3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EN1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EN1_01","description":"Genes having at least one occurence of the transcription factor binding site V$EN1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CCCNNNNNNAAGWT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCCNNNNNNAAGWT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M158 CCCNNNNNNAAGWT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AMEF2_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AMEF2_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AMEF2_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MMEF2_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MMEF2_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$MMEF2_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HMEF2_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HMEF2_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HMEF2_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"RSRFC4_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RSRFC4_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$RSRFC4_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SOX9_B1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SOX9_B1","description":"Genes having at least one occurence of the transcription factor binding site V$SOX9_B1 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF4_01_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF4_01_B","description":"Genes having at least one occurence of the transcription factor binding site V$HNF4_01_B (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AREB6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AREB6_01","description":"Genes having at least one occurence of the transcription factor binding site V$AREB6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AREB6_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AREB6_02","description":"Genes having at least one occurence of the transcription factor binding site V$AREB6_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AREB6_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AREB6_03","description":"Genes having at least one occurence of the transcription factor binding site V$AREB6_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AREB6_04","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AREB6_04","description":"Genes having at least one occurence of the transcription factor binding site V$AREB6_04 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CCGNMNNTNACG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCGNMNNTNACG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M106 CCGNMNNTNACG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CART1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CART1_01","description":"Genes having at least one occurence of the transcription factor binding site V$CART1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TGIF_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGIF_01","description":"Genes having at least one occurence of the transcription factor binding site V$TGIF_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MEIS1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEIS1_01","description":"Genes having at least one occurence of the transcription factor binding site V$MEIS1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MEIS1AHOXA9_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEIS1AHOXA9_01","description":"Genes having at least one occurence of the transcription factor binding site V$MEIS1AHOXA9_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MEIS1BHOXA9_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEIS1BHOXA9_01","description":"Genes having at least one occurence of the transcription factor binding site V$MEIS1BHOXA9_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOXJ2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXJ2_01","description":"Genes having at least one occurence of the transcription factor binding site V$FOXJ2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOXJ2_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXJ2_02","description":"Genes having at least one occurence of the transcription factor binding site V$FOXJ2_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NKX61_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NKX61_01","description":"Genes having at least one occurence of the transcription factor binding site V$NKX61_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CCTNTMAGA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCTNTMAGA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M167 CCTNTMAGA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"E2F_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F1_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F1_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TITF1_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TITF1_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$TITF1_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HMX1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HMX1_01","description":"Genes having at least one occurence of the transcription factor binding site V$HMX1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IPF1_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IPF1_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$IPF1_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CHX10_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CHX10_01","description":"Genes having at least one occurence of the transcription factor binding site V$CHX10_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"VDR_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VDR_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$VDR_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SPZ1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SPZ1_01","description":"Genes having at least one occurence of the transcription factor binding site V$SPZ1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CGGAARNGGCNG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CGGAARNGGCNG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M81 CGGAARNGGCNG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AR_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AR_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$AR_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ZIC1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZIC1_01","description":"Genes having at least one occurence of the transcription factor binding site V$ZIC1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ZIC2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZIC2_01","description":"Genes having at least one occurence of the transcription factor binding site V$ZIC2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ZIC3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZIC3_01","description":"Genes having at least one occurence of the transcription factor binding site V$ZIC3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NKX3A_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NKX3A_01","description":"Genes having at least one occurence of the transcription factor binding site V$NKX3A_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IRF7_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IRF7_01","description":"Genes having at least one occurence of the transcription factor binding site V$IRF7_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FAC1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FAC1_01","description":"Genes having at least one occurence of the transcription factor binding site V$FAC1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT5A_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT5A_01","description":"Genes having at least one occurence of the transcription factor binding site V$STAT5A_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT5B_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT5B_01","description":"Genes having at least one occurence of the transcription factor binding site V$STAT5B_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT5A_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT5A_02","description":"Genes having at least one occurence of the transcription factor binding site V$STAT5A_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CRGAARNNNNCGA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CRGAARNNNNCGA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M100 CRGAARNNNNCGA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"GATA6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA6_01","description":"Genes having at least one occurence of the transcription factor binding site V$GATA6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"POU3F2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POU3F2_01","description":"Genes having at least one occurence of the transcription factor binding site V$POU3F2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"POU3F2_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POU3F2_02","description":"Genes having at least one occurence of the transcription factor binding site V$POU3F2_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"POU6F1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POU6F1_01","description":"Genes having at least one occurence of the transcription factor binding site V$POU6F1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HIF1_Q5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HIF1_Q5","description":"Genes having at least one occurence of the transcription factor binding site V$HIF1_Q5 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ROAZ_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ROAZ_01","description":"Genes having at least one occurence of the transcription factor binding site V$ROAZ_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP2REP_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP2REP_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP2REP_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP2ALPHA_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP2ALPHA_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP2ALPHA_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP2GAMMA_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP2GAMMA_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP2GAMMA_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TBP_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TBP_01","description":"Genes having at least one occurence of the transcription factor binding site V$TBP_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CTCNANGTGNY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTCNANGTGNY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M171 CTCNANGTGNY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"FOXO4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXO4_01","description":"Genes having at least one occurence of the transcription factor binding site V$FOXO4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOXO1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXO1_01","description":"Genes having at least one occurence of the transcription factor binding site V$FOXO1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOXO1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXO1_02","description":"Genes having at least one occurence of the transcription factor binding site V$FOXO1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOXO4_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXO4_02","description":"Genes having at least one occurence of the transcription factor binding site V$FOXO4_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOXO3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXO3_01","description":"Genes having at least one occurence of the transcription factor binding site V$FOXO3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CDC5_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CDC5_01","description":"Genes having at least one occurence of the transcription factor binding site V$CDC5_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AR_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AR_01","description":"Genes having at least one occurence of the transcription factor binding site V$AR_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PITX2_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PITX2_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$PITX2_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ATF6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF6_01","description":"Genes having at least one occurence of the transcription factor binding site V$ATF6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NCX_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NCX_01","description":"Genes having at least one occurence of the transcription factor binding site V$NCX_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CTGCAGY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTGCAGY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M101 CTGCAGY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"NKX22_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NKX22_01","description":"Genes having at least one occurence of the transcription factor binding site V$NKX22_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX2_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX2_02","description":"Genes having at least one occurence of the transcription factor binding site V$PAX2_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NKX62_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NKX62_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$NKX62_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"BACH2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BACH2_01","description":"Genes having at least one occurence of the transcription factor binding site V$BACH2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MAZR_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAZR_01","description":"Genes having at least one occurence of the transcription factor binding site V$MAZR_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT1_02","description":"Genes having at least one occurence of the transcription factor binding site V$STAT1_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT5A_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT5A_03","description":"Genes having at least one occurence of the transcription factor binding site V$STAT5A_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT6_01","description":"Genes having at least one occurence of the transcription factor binding site V$STAT6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"BACH1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BACH1_01","description":"Genes having at least one occurence of the transcription factor binding site V$BACH1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT1_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT1_03","description":"Genes having at least one occurence of the transcription factor binding site V$STAT1_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CTGRYYYNATT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTGRYYYNATT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M153 CTGRYYYNATT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"STAT3_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT3_02","description":"Genes having at least one occurence of the transcription factor binding site V$STAT3_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT4_01","description":"Genes having at least one occurence of the transcription factor binding site V$STAT4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT5A_04","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT5A_04","description":"Genes having at least one occurence of the transcription factor binding site V$STAT5A_04 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT6_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT6_02","description":"Genes having at least one occurence of the transcription factor binding site V$STAT6_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LHX3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LHX3_01","description":"Genes having at least one occurence of the transcription factor binding site V$LHX3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ERR1_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ERR1_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$ERR1_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PPARG_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PPARG_01","description":"Genes having at least one occurence of the transcription factor binding site V$PPARG_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ATF3_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF3_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$ATF3_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ATF4_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF4_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$ATF4_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_03","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CTGYNNCTYTAA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTGYNNCTYTAA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M82 CTGYNNCTYTAA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PPARA_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PPARA_02","description":"Genes having at least one occurence of the transcription factor binding site V$PPARA_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GNCF_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNCF_01","description":"Genes having at least one occurence of the transcription factor binding site V$GNCF_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NERF_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NERF_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$NERF_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"RP58_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RP58_01","description":"Genes having at least one occurence of the transcription factor binding site V$RP58_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HTF_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HTF_01","description":"Genes having at least one occurence of the transcription factor binding site V$HTF_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ARNT_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ARNT_02","description":"Genes having at least one occurence of the transcription factor binding site V$ARNT_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYCMAX_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYCMAX_03","description":"Genes having at least one occurence of the transcription factor binding site V$MYCMAX_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AFP1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AFP1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AFP1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ALX4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALX4_01","description":"Genes having at least one occurence of the transcription factor binding site V$ALX4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CTTTAAR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTTTAAR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M29 CTTTAAR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CEBPDELTA_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBPDELTA_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$CEBPDELTA_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBPGAMMA_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBPGAMMA_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$CEBPGAMMA_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CRX_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CRX_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$CRX_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"DBP_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DBP_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$DBP_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EFC_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EFC_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$EFC_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOXM1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOXM1_01","description":"Genes having at least one occurence of the transcription factor binding site V$FOXM1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FXR_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FXR_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$FXR_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA4_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA4_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$GATA4_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GCM_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$GCM_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF4ALPHA_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF4ALPHA_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HNF4ALPHA_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CYTAGCAAY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CYTAGCAAY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M34 CYTAGCAAY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"HNF6_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF6_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HNF6_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HOXA4_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOXA4_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$HOXA4_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HSF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HSF_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HSF_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LBP1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LBP1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$LBP1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LFA1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LFA1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$LFA1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LXR_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LXR_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$LXR_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MAF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAF_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$MAF_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MAZ_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MAZ_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$MAZ_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MTF1_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MTF1_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$MTF1_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFMUE1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFMUE1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$NFMUE1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GAANYNYGACNY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAANYNYGACNY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M137 GAANYNYGACNY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"NRF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NRF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$NRF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PEA3_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PEA3_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$PEA3_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PTF1BETA_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PTF1BETA_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$PTF1BETA_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PU1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PU1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$PU1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SP3_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SP3_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$SP3_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TCF1P_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCF1P_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$TCF1P_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TCF4_Q5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCF4_Q5","description":"Genes having at least one occurence of the transcription factor binding site V$TCF4_Q5 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TEF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TEF_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$TEF_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TEL2_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TEL2_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$TEL2_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ALPHACP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALPHACP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$ALPHACP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATGKMRGCG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATGKMRGCG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M148 GATGKMRGCG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AP3_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP3_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AP3_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ATF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$ATF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E12_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E12_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$E12_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E4F1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E4F1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$E4F1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ETF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ETF_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$ETF_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HEB_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HEB_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HEB_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ICSBP_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ICSBP_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$ICSBP_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SMAD3_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMAD3_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$SMAD3_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TEF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TEF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$TEF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"TFIII_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TFIII_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$TFIII_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GCCNNNWTAAR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCCNNNWTAAR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M95 GCCNNNWTAAR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TFIIA_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TFIIA_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$TFIIA_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYOGENIN_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYOGENIN_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$MYOGENIN_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ZF5_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ZF5_01","description":"Genes having at least one occurence of the transcription factor binding site V$ZF5_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX8_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX8_01","description":"Genes having at least one occurence of the transcription factor binding site V$PAX8_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CACBINDINGPROTEIN_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CACBINDINGPROTEIN_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$CACBINDINGPROTEIN_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CACCCBINDINGFACTOR_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CACCCBINDINGFACTOR_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$CACCCBINDINGFACTOR_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"COREBINDINGFACTOR_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COREBINDINGFACTOR_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$COREBINDINGFACTOR_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF3ALPHA_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF3ALPHA_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HNF3ALPHA_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HP1SITEFACTOR_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HP1SITEFACTOR_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HP1SITEFACTOR_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"USF2_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/USF2_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$USF2_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GCGNNANTTCC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCGNNANTTCC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M48 GCGNNANTTCC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"SF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$SF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CDX2_Q5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CDX2_Q5","description":"Genes having at least one occurence of the transcription factor binding site V$CDX2_Q5 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OSF2_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OSF2_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$OSF2_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SMAD4_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMAD4_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$SMAD4_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CIZ_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CIZ_01","description":"Genes having at least one occurence of the transcription factor binding site V$CIZ_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F1DP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1DP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1DP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F1DP2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1DP2_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1DP2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F4DP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F4DP1_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F4DP1_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F4DP2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F4DP2_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F4DP2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F1DP1RB_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1DP1RB_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1DP1RB_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GCGSCMNTTT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCGSCMNTTT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M164 GCGSCMNTTT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"HFH4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HFH4_01","description":"Genes having at least one occurence of the transcription factor binding site V$HFH4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"POU1F1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/POU1F1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$POU1F1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LEF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$LEF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ELF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ELF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$ELF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IRF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IRF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$IRF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SREBP1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SREBP1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$SREBP1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HMGIY_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HMGIY_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HMGIY_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AML1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AML1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AML1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"P53_DECAMER_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/P53_DECAMER_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$P53_DECAMER_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"DR1_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DR1_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$DR1_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GCTNWTTGK_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCTNWTTGK_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M78 GCTNWTTGK in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"PPAR_DR1_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PPAR_DR1_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$PPAR_DR1_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF4_DR1_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF4_DR1_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$HNF4_DR1_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"COUP_DR1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/COUP_DR1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$COUP_DR1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"LXR_DR4_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LXR_DR4_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$LXR_DR4_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FXR_IR1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FXR_IR1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$FXR_IR1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AML_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AML_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AML_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBP_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBP_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$CEBP_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ETS_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ETS_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$ETS_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"IRF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IRF_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$IRF_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYB_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYB_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$MYB_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GGAANCGGAANY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGAANCGGAANY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M21 GGAANCGGAANY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"NFKB_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFKB_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$NFKB_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFY_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFY_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$NFY_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SREBP_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SREBP_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$SREBP_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"STAT_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STAT_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$STAT_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AHR_Q5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AHR_Q5","description":"Genes having at least one occurence of the transcription factor binding site V$AHR_Q5 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GATA_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATA_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$GATA_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HNF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF3_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF3_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HNF3_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SMAD_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMAD_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$SMAD_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"YY1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YY1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$YY1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GGAMTNNNNNTCCY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGAMTNNNNNTCCY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M74 GGAMTNNNNNTCCY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TTF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTF1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$TTF1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OCT_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$OCT_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"USF_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/USF_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$USF_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HIF1_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HIF1_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$HIF1_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYC_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYC_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$MYC_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP2_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP2_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$AP2_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREB_Q3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREB_Q3","description":"Genes having at least one occurence of the transcription factor binding site V$CREB_Q3 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PIT1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PIT1_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$PIT1_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2A_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2A_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$E2A_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GGARNTKYCCA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGARNTKYCCA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M163 GGARNTKYCCA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"LEF1_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEF1_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$LEF1_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NF1_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NF1_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$NF1_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"EGR_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EGR_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$EGR_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PAX_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PAX_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$PAX_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"FOX_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/FOX_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$FOX_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SRF_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRF_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$SRF_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NRF2_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NRF2_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$NRF2_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CEBP_Q2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CEBP_Q2_01","description":"Genes having at least one occurence of the transcription factor binding site V$CEBP_Q2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYB_Q5_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYB_Q5_01","description":"Genes having at least one occurence of the transcription factor binding site V$MYB_Q5_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ER_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ER_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$ER_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GGCKCATGS_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCKCATGS_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M159 GGCKCATGS in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AP2_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP2_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP2_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREB_Q2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREB_Q2_01","description":"Genes having at least one occurence of the transcription factor binding site V$CREB_Q2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CREB_Q4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CREB_Q4_01","description":"Genes having at least one occurence of the transcription factor binding site V$CREB_Q4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_Q3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_Q3_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_Q3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_Q4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_Q4_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_Q4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GR_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GR_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$GR_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SRF_Q5_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRF_Q5_01","description":"Genes having at least one occurence of the transcription factor binding site V$SRF_Q5_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP1_Q2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1_Q2_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP1_Q2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP1_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP1_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GGCNKCCATNK_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCNKCCATNK_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M88 GGCNKCCATNK in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AP1_Q4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP1_Q4_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP1_Q4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AP4_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AP4_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$AP4_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MYOD_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYOD_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$MYOD_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"OCT1_Q5_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/OCT1_Q5_01","description":"Genes having at least one occurence of the transcription factor binding site V$OCT1_Q5_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SP1_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SP1_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$SP1_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SP1_Q4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SP1_Q4_01","description":"Genes having at least one occurence of the transcription factor binding site V$SP1_Q4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"SP1_Q2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SP1_Q2_01","description":"Genes having at least one occurence of the transcription factor binding site V$SP1_Q2_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"NFAT_Q4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFAT_Q4_01","description":"Genes having at least one occurence of the transcription factor binding site V$NFAT_Q4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F1_Q3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1_Q3_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1_Q3_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"E2F1_Q4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1_Q4_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1_Q4_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GGCNNMSMYNTTG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCNNMSMYNTTG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M123 GGCNNMSMYNTTG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"E2F1_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$E2F1_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"MEF2_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEF2_Q6_01","description":"Genes having at least one occurence of the transcription factor binding site V$MEF2_Q6_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"CP2_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CP2_02","description":"Genes having at least one occurence of the transcription factor binding site V$CP2_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AR_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AR_02","description":"Genes having at least one occurence of the transcription factor binding site V$AR_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PR_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PR_01","description":"Genes having at least one occurence of the transcription factor binding site V$PR_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GR_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GR_01","description":"Genes having at least one occurence of the transcription factor binding site V$GR_01 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AR_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AR_03","description":"Genes having at least one occurence of the transcription factor binding site V$AR_03 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PR_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PR_02","description":"Genes having at least one occurence of the transcription factor binding site V$PR_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"ER_Q6_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ER_Q6_02","description":"Genes having at least one occurence of the transcription factor binding site V$ER_Q6_02 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PR_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PR_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$PR_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"GGCNRNWCTTYS_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCNRNWCTTYS_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M118 GGCNRNWCTTYS in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"VDR_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VDR_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$VDR_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AR_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AR_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$AR_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"T3R_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/T3R_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$T3R_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"PXR_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PXR_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$PXR_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"DR4_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DR4_Q2","description":"Genes having at least one occurence of the transcription factor binding site V$DR4_Q2 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"DR3_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DR3_Q4","description":"Genes having at least one occurence of the transcription factor binding site V$DR3_Q4 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"HNF4_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HNF4_Q6","description":"Genes having at least one occurence of the transcription factor binding site V$HNF4_Q6 (v7.4 TRANSFAC) in the regions spanning up to 4 kb around their transcription starting sites."} {"geneset":"AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D","description":"Genes having at least one occurence of the motif AGCACTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-93, hsa-miR-302a, hsa-miR-302b, hsa-miR-302c, hsa-miR-302d, hsa-miR-372, hsa-miR-373, hsa-miR-520e, hsa-miR-520a, hsa-miR-526b*, hsa-miR-520b, hsa-miR-520c and hsa-miR-520d (v7.1 miRBase)."} {"geneset":"CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I","description":"Genes having at least one occurence of the motif CTACCTC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-let-7a, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f, hsa-miR-98, hsa-let-7g and hsa-let-7i (v7.1 miRBase)."} {"geneset":"GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D","description":"Genes having at least one occurence of the motif GCACTTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-17-5p, hsa-miR-20a, hsa-miR-106a, hsa-miR-106b, hsa-miR-20b and hsa-miR-519d (v7.1 miRBase)."} {"geneset":"GGGNRMNNYCAT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGNRMNNYCAT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M119 GGGNRMNNYCAT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497","description":"Genes having at least one occurence of the motif TGCTGCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-15a, hsa-miR-16, hsa-miR-15b, hsa-miR-195, hsa-miR-424 and hsa-miR-497 (v7.1 miRBase)."} {"geneset":"TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P","description":"Genes having at least one occurence of the motif TGTTTAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-30a-5p, hsa-miR-30c, hsa-miR-30d, hsa-miR-30b and hsa-miR-30e-5p (v7.1 miRBase)."} {"geneset":"GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367","description":"Genes having at least one occurence of the motif GTGCAAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-25, hsa-miR-32, hsa-miR-92, hsa-miR-363 and hsa-miR-367 (v7.1 miRBase)."} {"geneset":"TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D","description":"Genes having at least one occurence of the motif TGAATGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-181a, hsa-miR-181b, hsa-miR-181c and hsa-miR-181d (v7.1 miRBase)."} {"geneset":"GCGCTTT_MIR518B_MIR518C_MIR518D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCGCTTT_MIR518B_MIR518C_MIR518D","description":"Genes having at least one occurence of the motif GCGCTTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-518b, hsa-miR-518c and hsa-miR-518d (v7.1 miRBase)."} {"geneset":"TGGTGCT_MIR29A_MIR29B_MIR29C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGGTGCT_MIR29A_MIR29B_MIR29C","description":"Genes having at least one occurence of the motif TGGTGCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-29a, hsa-miR-29b and hsa-miR-29c (v7.1 miRBase)."} {"geneset":"TGCACTG_MIR148A_MIR152_MIR148B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCACTG_MIR148A_MIR152_MIR148B","description":"Genes having at least one occurence of the motif TGCACTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-148a, hsa-miR-152 and hsa-miR-148b (v7.1 miRBase)."} {"geneset":"CACTGCC_MIR34A_MIR34C_MIR449","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CACTGCC_MIR34A_MIR34C_MIR449","description":"Genes having at least one occurence of the motif CACTGCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-34a, hsa-miR-34c and hsa-miR-449 (v7.1 miRBase)."} {"geneset":"TACGGGT_MIR99A_MIR100_MIR99B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TACGGGT_MIR99A_MIR100_MIR99B","description":"Genes having at least one occurence of the motif TACGGGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-99a, hsa-miR-100 and hsa-miR-99b (v7.1 miRBase)."} {"geneset":"CTCTAGA_MIR526C_MIR518F_MIR526A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTCTAGA_MIR526C_MIR518F_MIR526A","description":"Genes having at least one occurence of the motif CTCTAGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-526c, hsa-miR-518f* and hsa-miR-526a (v7.1 miRBase)."} {"geneset":"GGGYGTGNY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGYGTGNY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M31 GGGYGTGNY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TTGCACT_MIR130A_MIR301_MIR130B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTGCACT_MIR130A_MIR301_MIR130B","description":"Genes having at least one occurence of the motif TTGCACT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-130a, hsa-miR-301 and hsa-miR-130b (v7.1 miRBase)."} {"geneset":"TGCACTT_MIR519C_MIR519B_MIR519A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCACTT_MIR519C_MIR519B_MIR519A","description":"Genes having at least one occurence of the motif TGCACTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-519c, hsa-miR-519b and hsa-miR-519a (v7.1 miRBase)."} {"geneset":"AGCGCTT_MIR518F_MIR518E_MIR518A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGCGCTT_MIR518F_MIR518E_MIR518A","description":"Genes having at least one occurence of the motif AGCGCTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-518f, hsa-miR-518e and hsa-miR-518a (v7.1 miRBase)."} {"geneset":"CAGTATT_MIR200B_MIR200C_MIR429","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGTATT_MIR200B_MIR200C_MIR429","description":"Genes having at least one occurence of the motif CAGTATT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-200b, hsa-miR-200c and hsa-miR-429 (v7.1 miRBase)."} {"geneset":"ACATTCC_MIR1_MIR206","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACATTCC_MIR1_MIR206","description":"Genes having at least one occurence of the motif ACATTCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-1 and hsa-miR-206 (v7.1 miRBase)."} {"geneset":"AAGTCCA_MIR422B_MIR422A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAGTCCA_MIR422B_MIR422A","description":"Genes having at least one occurence of the motif AAGTCCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-422b and hsa-miR-422a (v7.1 miRBase)."} {"geneset":"AAAGGGA_MIR204_MIR211","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAAGGGA_MIR204_MIR211","description":"Genes having at least one occurence of the motif AAAGGGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-204 and hsa-miR-211 (v7.1 miRBase)."} {"geneset":"AATGTGA_MIR23A_MIR23B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AATGTGA_MIR23A_MIR23B","description":"Genes having at least one occurence of the motif AATGTGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-23a and hsa-miR-23b (v7.1 miRBase)."} {"geneset":"CACTGTG_MIR128A_MIR128B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CACTGTG_MIR128A_MIR128B","description":"Genes having at least one occurence of the motif CACTGTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-128a and hsa-miR-128b (v7.1 miRBase)."} {"geneset":"ACTGAAA_MIR30A3P_MIR30E3P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTGAAA_MIR30A3P_MIR30E3P","description":"Genes having at least one occurence of the motif ACTGAAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-30a-3p and hsa-miR-30e-3p (v7.1 miRBase)."} {"geneset":"GKCGCNNNNNNNTGAYG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GKCGCNNNNNNNTGAYG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M19 GKCGCNNNNNNNTGAYG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CTCAGGG_MIR125B_MIR125A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTCAGGG_MIR125B_MIR125A","description":"Genes having at least one occurence of the motif CTCAGGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-125b and hsa-miR-125a (v7.1 miRBase)."} {"geneset":"TACTTGA_MIR26A_MIR26B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TACTTGA_MIR26A_MIR26B","description":"Genes having at least one occurence of the motif TACTTGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-26a and hsa-miR-26b (v7.1 miRBase)."} {"geneset":"TCTATGA_MIR376A_MIR376B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCTATGA_MIR376A_MIR376B","description":"Genes having at least one occurence of the motif TCTATGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-376a and hsa-miR-376b (v7.1 miRBase)."} {"geneset":"GTATGAT_MIR154_MIR487","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTATGAT_MIR154_MIR487","description":"Genes having at least one occurence of the motif GTATGAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-154* and hsa-miR-487 (v7.1 miRBase)."} {"geneset":"CAGTGTT_MIR141_MIR200A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGTGTT_MIR141_MIR200A","description":"Genes having at least one occurence of the motif CAGTGTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-141 and hsa-miR-200a (v7.1 miRBase)."} {"geneset":"AGTTCTC_MIR146A_MIR146B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGTTCTC_MIR146A_MIR146B","description":"Genes having at least one occurence of the motif AGTTCTC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-146a and hsa-miR-146b (v7.1 miRBase)."} {"geneset":"TAGGTCA_MIR192_MIR215","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAGGTCA_MIR192_MIR215","description":"Genes having at least one occurence of the motif TAGGTCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-192 and hsa-miR-215 (v7.1 miRBase)."} {"geneset":"ATGTAGC_MIR221_MIR222","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGTAGC_MIR221_MIR222","description":"Genes having at least one occurence of the motif ATGTAGC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-221 and hsa-miR-222 (v7.1 miRBase)."} {"geneset":"ACTGTGA_MIR27A_MIR27B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTGTGA_MIR27A_MIR27B","description":"Genes having at least one occurence of the motif ACTGTGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-27a and hsa-miR-27b (v7.1 miRBase)."} {"geneset":"TGCACGA_MIR517A_MIR517C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCACGA_MIR517A_MIR517C","description":"Genes having at least one occurence of the motif TGCACGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-517a and hsa-miR-517c (v7.1 miRBase)."} {"geneset":"GTCNYYATGR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTCNYYATGR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M98 GTCNYYATGR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TTTGCAC_MIR19A_MIR19B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTTGCAC_MIR19A_MIR19B","description":"Genes having at least one occurence of the motif TTTGCAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-19a and hsa-miR-19b (v7.1 miRBase)."} {"geneset":"ACTACCT_MIR196A_MIR196B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTACCT_MIR196A_MIR196B","description":"Genes having at least one occurence of the motif ACTACCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-196a and hsa-miR-196b (v7.1 miRBase)."} {"geneset":"TTGGAGA_MIR5155P_MIR519E","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTGGAGA_MIR5155P_MIR519E","description":"Genes having at least one occurence of the motif TTGGAGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-515-5p and hsa-miR-519e* (v7.1 miRBase)."} {"geneset":"CACTTTG_MIR520G_MIR520H","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CACTTTG_MIR520G_MIR520H","description":"Genes having at least one occurence of the motif CACTTTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-520g and hsa-miR-520h (v7.1 miRBase)."} {"geneset":"GGGACCA_MIR133A_MIR133B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGACCA_MIR133A_MIR133B","description":"Genes having at least one occurence of the motif GGGACCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-133a and hsa-miR-133b (v7.1 miRBase)."} {"geneset":"GACTGTT_MIR212_MIR132","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GACTGTT_MIR212_MIR132","description":"Genes having at least one occurence of the motif GACTGTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-212 and hsa-miR-132 (v7.1 miRBase)."} {"geneset":"AAGCCAT_MIR135A_MIR135B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAGCCAT_MIR135A_MIR135B","description":"Genes having at least one occurence of the motif AAGCCAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-135a and hsa-miR-135b (v7.1 miRBase)."} {"geneset":"ATGCTGC_MIR103_MIR107","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGCTGC_MIR103_MIR107","description":"Genes having at least one occurence of the motif ATGCTGC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-103 and hsa-miR-107 (v7.1 miRBase)."} {"geneset":"ACAGGGT_MIR10A_MIR10B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACAGGGT_MIR10A_MIR10B","description":"Genes having at least one occurence of the motif ACAGGGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-10a and hsa-miR-10b (v7.1 miRBase)."} {"geneset":"CTCTGGA_MIR520A_MIR525","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTCTGGA_MIR520A_MIR525","description":"Genes having at least one occurence of the motif CTCTGGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-520a* and hsa-miR-525 (v7.1 miRBase)."} {"geneset":"GTGGGTGK_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGGGTGK_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M91 GTGGGTGK in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"GCGCCTT_MIR525_MIR524","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCGCCTT_MIR525_MIR524","description":"Genes having at least one occurence of the motif GCGCCTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-525* and hsa-miR-524 (v7.1 miRBase)."} {"geneset":"ACACTGG_MIR199A_MIR199B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACACTGG_MIR199A_MIR199B","description":"Genes having at least one occurence of the motif ACACTGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-199a and hsa-miR-199b (v7.1 miRBase)."} {"geneset":"GCACCTT_MIR18A_MIR18B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCACCTT_MIR18A_MIR18B","description":"Genes having at least one occurence of the motif GCACCTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-18a and hsa-miR-18b (v7.1 miRBase)."} {"geneset":"GGCCAGT_MIR193A_MIR193B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCCAGT_MIR193A_MIR193B","description":"Genes having at least one occurence of the motif GGCCAGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNAs hsa-miR-193a and hsa-miR-193b (v7.1 miRBase)."} {"geneset":"CGCTGCT_MIR503","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CGCTGCT_MIR503","description":"Genes having at least one occurence of the motif CGCTGCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-503 (v7.1 miRBase)."} {"geneset":"TCTGATC_MIR383","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCTGATC_MIR383","description":"Genes having at least one occurence of the motif TCTGATC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-383 (v7.1 miRBase)."} {"geneset":"GTGCCTT_MIR506","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGCCTT_MIR506","description":"Genes having at least one occurence of the motif GTGCCTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-506 (v7.1 miRBase)."} {"geneset":"ACAACTT_MIR382","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACAACTT_MIR382","description":"Genes having at least one occurence of the motif ACAACTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-382 (v7.1 miRBase)."} {"geneset":"ATGTTAA_MIR302C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGTTAA_MIR302C","description":"Genes having at least one occurence of the motif ATGTTAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-302c* (v7.1 miRBase)."} {"geneset":"GGATCCG_MIR127","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGATCCG_MIR127","description":"Genes having at least one occurence of the motif GGATCCG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-127 (v7.1 miRBase)."} {"geneset":"GTTGNYNNRGNAAC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTTGNYNNRGNAAC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M43 GTTGNYNNRGNAAC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CATTTCA_MIR203","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CATTTCA_MIR203","description":"Genes having at least one occurence of the motif CATTTCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-203 (v7.1 miRBase)."} {"geneset":"TCCAGAT_MIR5165P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCCAGAT_MIR5165P","description":"Genes having at least one occurence of the motif TCCAGAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-516-5p (v7.1 miRBase)."} {"geneset":"AGTCAGC_MIR345","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGTCAGC_MIR345","description":"Genes having at least one occurence of the motif AGTCAGC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-345 (v7.1 miRBase)."} {"geneset":"ACACTCC_MIR122A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACACTCC_MIR122A","description":"Genes having at least one occurence of the motif ACACTCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-122a (v7.1 miRBase)."} {"geneset":"GTGTGAG_MIR342","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGTGAG_MIR342","description":"Genes having at least one occurence of the motif GTGTGAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-342 (v7.1 miRBase)."} {"geneset":"CTAGGAA_MIR384","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTAGGAA_MIR384","description":"Genes having at least one occurence of the motif CTAGGAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-384 (v7.1 miRBase)."} {"geneset":"CTATGCA_MIR153","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTATGCA_MIR153","description":"Genes having at least one occurence of the motif CTATGCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-153 (v7.1 miRBase)."} {"geneset":"AGGGCAG_MIR18A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGGGCAG_MIR18A","description":"Genes having at least one occurence of the motif AGGGCAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-18a* (v7.1 miRBase)."} {"geneset":"GTGCCAT_MIR183","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGCCAT_MIR183","description":"Genes having at least one occurence of the motif GTGCCAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-183 (v7.1 miRBase)."} {"geneset":"ACTGCAG_MIR173P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTGCAG_MIR173P","description":"Genes having at least one occurence of the motif ACTGCAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-17-3p (v7.1 miRBase)."} {"geneset":"GTTNYYNNGGTNA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTTNYYNNGGTNA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M89 GTTNYYNNGGTNA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"GTTTGTT_MIR495","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTTTGTT_MIR495","description":"Genes having at least one occurence of the motif GTTTGTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-495 (v7.1 miRBase)."} {"geneset":"TATTATA_MIR374","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TATTATA_MIR374","description":"Genes having at least one occurence of the motif TATTATA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-374 (v7.1 miRBase)."} {"geneset":"CTTGTAT_MIR381","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTTGTAT_MIR381","description":"Genes having at least one occurence of the motif CTTGTAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-381 (v7.1 miRBase)."} {"geneset":"AAAGGAT_MIR501","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAAGGAT_MIR501","description":"Genes having at least one occurence of the motif AAAGGAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-501 (v7.1 miRBase)."} {"geneset":"GGGGCCC_MIR296","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGGCCC_MIR296","description":"Genes having at least one occurence of the motif GGGGCCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-296 (v7.1 miRBase)."} {"geneset":"CTACTGT_MIR199A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTACTGT_MIR199A","description":"Genes having at least one occurence of the motif CTACTGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-199a* (v7.1 miRBase)."} {"geneset":"CAAGGAT_MIR362","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAAGGAT_MIR362","description":"Genes having at least one occurence of the motif CAAGGAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-362 (v7.1 miRBase)."} {"geneset":"GTGTTGA_MIR505","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGTTGA_MIR505","description":"Genes having at least one occurence of the motif GTGTTGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-505 (v7.1 miRBase)."} {"geneset":"ATACTGT_MIR144","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATACTGT_MIR144","description":"Genes having at least one occurence of the motif ATACTGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-144 (v7.1 miRBase)."} {"geneset":"TGTATGA_MIR4853P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGTATGA_MIR4853P","description":"Genes having at least one occurence of the motif TGTATGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-485-3p (v7.1 miRBase)."} {"geneset":"GTTRYCATRR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTTRYCATRR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M37 GTTRYCATRR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"GTATTAT_MIR3693P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTATTAT_MIR3693P","description":"Genes having at least one occurence of the motif GTATTAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-369-3p (v7.1 miRBase)."} {"geneset":"TCCCCAC_MIR491","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCCCCAC_MIR491","description":"Genes having at least one occurence of the motif TCCCCAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-491 (v7.1 miRBase)."} {"geneset":"GCTTGAA_MIR498","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCTTGAA_MIR498","description":"Genes having at least one occurence of the motif GCTTGAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-498 (v7.1 miRBase)."} {"geneset":"GTGGTGA_MIR197","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGGTGA_MIR197","description":"Genes having at least one occurence of the motif GTGGTGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-197 (v7.1 miRBase)."} {"geneset":"GGGCATT_MIR365","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGCATT_MIR365","description":"Genes having at least one occurence of the motif GGGCATT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-365 (v7.1 miRBase)."} {"geneset":"TGAGATT_MIR216","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGAGATT_MIR216","description":"Genes having at least one occurence of the motif TGAGATT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-216 (v7.1 miRBase)."} {"geneset":"GTCAACC_MIR3805P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTCAACC_MIR3805P","description":"Genes having at least one occurence of the motif GTCAACC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-380-5p (v7.1 miRBase)."} {"geneset":"GGTGAAG_MIR412","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGTGAAG_MIR412","description":"Genes having at least one occurence of the motif GGTGAAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-412 (v7.1 miRBase)."} {"geneset":"AGGGCCA_MIR328","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGGGCCA_MIR328","description":"Genes having at least one occurence of the motif AGGGCCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-328 (v7.1 miRBase)."} {"geneset":"GTGACTT_MIR224","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGACTT_MIR224","description":"Genes having at least one occurence of the motif GTGACTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-224 (v7.1 miRBase)."} {"geneset":"KCCGNSWTTT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KCCGNSWTTT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M157 KCCGNSWTTT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"GAGACTG_MIR452","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAGACTG_MIR452","description":"Genes having at least one occurence of the motif GAGACTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-452* (v7.1 miRBase)."} {"geneset":"CAGGGTC_MIR504","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGGGTC_MIR504","description":"Genes having at least one occurence of the motif CAGGGTC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-504 (v7.1 miRBase)."} {"geneset":"GCTCTTG_MIR335","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCTCTTG_MIR335","description":"Genes having at least one occurence of the motif GCTCTTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-335 (v7.1 miRBase)."} {"geneset":"TCGATGG_MIR213","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCGATGG_MIR213","description":"Genes having at least one occurence of the motif TCGATGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-213 (v7.1 miRBase)."} {"geneset":"GTCTTCC_MIR7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTCTTCC_MIR7","description":"Genes having at least one occurence of the motif GTCTTCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-7 (v7.1 miRBase)."} {"geneset":"ATAACCT_MIR154","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATAACCT_MIR154","description":"Genes having at least one occurence of the motif ATAACCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-154 (v7.1 miRBase)."} {"geneset":"TCTAGAG_MIR517","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCTAGAG_MIR517","description":"Genes having at least one occurence of the motif TCTAGAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-517* (v7.1 miRBase)."} {"geneset":"GGCAGAC_MIR346","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCAGAC_MIR346","description":"Genes having at least one occurence of the motif GGCAGAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-346 (v7.1 miRBase)."} {"geneset":"AGGCACT_MIR5153P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGGCACT_MIR5153P","description":"Genes having at least one occurence of the motif AGGCACT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-515-3p (v7.1 miRBase)."} {"geneset":"ATAGGAA_MIR202","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATAGGAA_MIR202","description":"Genes having at least one occurence of the motif ATAGGAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-202* (v7.1 miRBase)."} {"geneset":"KMCATNNWGGA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KMCATNNWGGA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M116 KMCATNNWGGA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CCAGGTT_MIR490","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCAGGTT_MIR490","description":"Genes having at least one occurence of the motif CCAGGTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-490 (v7.1 miRBase)."} {"geneset":"TTGCCAA_MIR182","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTGCCAA_MIR182","description":"Genes having at least one occurence of the motif TTGCCAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-182 (v7.1 miRBase)."} {"geneset":"CGGTGTG_MIR220","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CGGTGTG_MIR220","description":"Genes having at least one occurence of the motif CGGTGTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-220 (v7.1 miRBase)."} {"geneset":"TAGCTTT_MIR9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAGCTTT_MIR9","description":"Genes having at least one occurence of the motif TAGCTTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-9* (v7.1 miRBase)."} {"geneset":"CTGAGCC_MIR24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTGAGCC_MIR24","description":"Genes having at least one occurence of the motif CTGAGCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-24 (v7.1 miRBase)."} {"geneset":"TTGGGAG_MIR150","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTGGGAG_MIR150","description":"Genes having at least one occurence of the motif TTGGGAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-150 (v7.1 miRBase)."} {"geneset":"AAACCAC_MIR140","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAACCAC_MIR140","description":"Genes having at least one occurence of the motif AAACCAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-140 (v7.1 miRBase)."} {"geneset":"CCCACAT_MIR2993P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCCACAT_MIR2993P","description":"Genes having at least one occurence of the motif CCCACAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-299-3p (v7.1 miRBase)."} {"geneset":"ATGTTTC_MIR494","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGTTTC_MIR494","description":"Genes having at least one occurence of the motif ATGTTTC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-494 (v7.1 miRBase)."} {"geneset":"GTACTGT_MIR101","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTACTGT_MIR101","description":"Genes having at least one occurence of the motif GTACTGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-101 (v7.1 miRBase)."} {"geneset":"KRCTCNNNNMANAGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRCTCNNNNMANAGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M120 KRCTCNNNNMANAGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CAGGTCC_MIR492","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGGTCC_MIR492","description":"Genes having at least one occurence of the motif CAGGTCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-492 (v7.1 miRBase)."} {"geneset":"GAGCCTG_MIR484","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAGCCTG_MIR484","description":"Genes having at least one occurence of the motif GAGCCTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-484 (v7.1 miRBase)."} {"geneset":"GTAAGAT_MIR200A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTAAGAT_MIR200A","description":"Genes having at least one occurence of the motif GTAAGAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-200a* (v7.1 miRBase)."} {"geneset":"TCCGTCC_MIR184","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCCGTCC_MIR184","description":"Genes having at least one occurence of the motif TCCGTCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-184 (v7.1 miRBase)."} {"geneset":"CACGTTT_MIR302A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CACGTTT_MIR302A","description":"Genes having at least one occurence of the motif CACGTTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-302a* (v7.1 miRBase)."} {"geneset":"TATCTGG_MIR488","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TATCTGG_MIR488","description":"Genes having at least one occurence of the motif TATCTGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-488 (v7.1 miRBase)."} {"geneset":"AGGAAGC_MIR5163P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGGAAGC_MIR5163P","description":"Genes having at least one occurence of the motif AGGAAGC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-516-3p (v7.1 miRBase)."} {"geneset":"ACGCACA_MIR210","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACGCACA_MIR210","description":"Genes having at least one occurence of the motif ACGCACA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-210 (v7.1 miRBase)."} {"geneset":"ATATGCA_MIR448","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATATGCA_MIR448","description":"Genes having at least one occurence of the motif ATATGCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-448 (v7.1 miRBase)."} {"geneset":"AATGGAG_MIR136","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AATGGAG_MIR136","description":"Genes having at least one occurence of the motif AATGGAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-136 (v7.1 miRBase)."} {"geneset":"KTGGYRSGAA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KTGGYRSGAA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M112 KTGGYRSGAA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CCTGTGA_MIR513","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCTGTGA_MIR513","description":"Genes having at least one occurence of the motif CCTGTGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-513 (v7.1 miRBase)."} {"geneset":"AACGGTT_MIR451","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AACGGTT_MIR451","description":"Genes having at least one occurence of the motif AACGGTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-451 (v7.1 miRBase)."} {"geneset":"ATGAAGG_MIR205","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGAAGG_MIR205","description":"Genes having at least one occurence of the motif ATGAAGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-205 (v7.1 miRBase)."} {"geneset":"CTCAAGA_MIR526B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTCAAGA_MIR526B","description":"Genes having at least one occurence of the motif CTCAAGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-526b (v7.1 miRBase)."} {"geneset":"GGCAGCT_MIR22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCAGCT_MIR22","description":"Genes having at least one occurence of the motif GGCAGCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-22 (v7.1 miRBase)."} {"geneset":"TCTGGAC_MIR198","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCTGGAC_MIR198","description":"Genes having at least one occurence of the motif TCTGGAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-198 (v7.1 miRBase)."} {"geneset":"CAGCTTT_MIR320","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGCTTT_MIR320","description":"Genes having at least one occurence of the motif CAGCTTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-320 (v7.1 miRBase)."} {"geneset":"CCATCCA_MIR432","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCATCCA_MIR432","description":"Genes having at least one occurence of the motif CCATCCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-432* (v7.1 miRBase)."} {"geneset":"CATGTAA_MIR496","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CATGTAA_MIR496","description":"Genes having at least one occurence of the motif CATGTAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-496 (v7.1 miRBase)."} {"geneset":"AAGCACA_MIR218","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAGCACA_MIR218","description":"Genes having at least one occurence of the motif AAGCACA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-218 (v7.1 miRBase)."} {"geneset":"MCAATNNNNNGCG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MCAATNNNNNGCG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M110 MCAATNNNNNGCG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"GCAAGAC_MIR431","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCAAGAC_MIR431","description":"Genes having at least one occurence of the motif GCAAGAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-431 (v7.1 miRBase)."} {"geneset":"ATGTCAC_MIR489","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGTCAC_MIR489","description":"Genes having at least one occurence of the motif ATGTCAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-489 (v7.1 miRBase)."} {"geneset":"CCTGCTG_MIR214","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCTGCTG_MIR214","description":"Genes having at least one occurence of the motif CCTGCTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-214 (v7.1 miRBase)."} {"geneset":"GTCTACC_MIR379","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTCTACC_MIR379","description":"Genes having at least one occurence of the motif GTCTACC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-379 (v7.1 miRBase)."} {"geneset":"CTACTAG_MIR325","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTACTAG_MIR325","description":"Genes having at least one occurence of the motif CTACTAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-325 (v7.1 miRBase)."} {"geneset":"CCTGAGT_MIR510","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCTGAGT_MIR510","description":"Genes having at least one occurence of the motif CCTGAGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-510 (v7.1 miRBase)."} {"geneset":"GACAGGG_MIR339","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GACAGGG_MIR339","description":"Genes having at least one occurence of the motif GACAGGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-339 (v7.1 miRBase)."} {"geneset":"ATACCTC_MIR202","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATACCTC_MIR202","description":"Genes having at least one occurence of the motif ATACCTC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-202 (v7.1 miRBase)."} {"geneset":"GGCAGTG_MIR3243P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCAGTG_MIR3243P","description":"Genes having at least one occurence of the motif GGCAGTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-324-3p (v7.1 miRBase)."} {"geneset":"MYAATNNNNNNNGGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYAATNNNNNNNGGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M138 MYAATNNNNNNNGGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"GAGCCAG_MIR149","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAGCCAG_MIR149","description":"Genes having at least one occurence of the motif GAGCCAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-149 (v7.1 miRBase)."} {"geneset":"TCTCTCC_MIR185","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCTCTCC_MIR185","description":"Genes having at least one occurence of the motif TCTCTCC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-185 (v7.1 miRBase)."} {"geneset":"AGCATTA_MIR155","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGCATTA_MIR155","description":"Genes having at least one occurence of the motif AGCATTA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-155 (v7.1 miRBase)."} {"geneset":"GCAAAAA_MIR129","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCAAAAA_MIR129","description":"Genes having at least one occurence of the motif GCAAAAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-129 (v7.1 miRBase)."} {"geneset":"GGCACAT_MIR455","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCACAT_MIR455","description":"Genes having at least one occurence of the motif GGCACAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-455 (v7.1 miRBase)."} {"geneset":"GTCGATC_MIR3695P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTCGATC_MIR3695P","description":"Genes having at least one occurence of the motif GTCGATC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-369-5p (v7.1 miRBase)."} {"geneset":"GGCGGCA_MIR371","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCGGCA_MIR371","description":"Genes having at least one occurence of the motif GGCGGCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-371 (v7.1 miRBase)."} {"geneset":"CTTTGTA_MIR524","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTTTGTA_MIR524","description":"Genes having at least one occurence of the motif CTTTGTA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-524* (v7.1 miRBase)."} {"geneset":"CTGTTAC_MIR194","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTGTTAC_MIR194","description":"Genes having at least one occurence of the motif CTGTTAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-194 (v7.1 miRBase)."} {"geneset":"ATGCAGT_MIR217","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGCAGT_MIR217","description":"Genes having at least one occurence of the motif ATGCAGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-217 (v7.1 miRBase)."} {"geneset":"RAAGNYNNCTTY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAAGNYNNCTTY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M125 RAAGNYNNCTTY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"ATGCTGG_MIR338","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGCTGG_MIR338","description":"Genes having at least one occurence of the motif ATGCTGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-338 (v7.1 miRBase)."} {"geneset":"ACATATC_MIR190","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACATATC_MIR190","description":"Genes having at least one occurence of the motif ACATATC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-190 (v7.1 miRBase)."} {"geneset":"CTCCAAG_MIR432","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTCCAAG_MIR432","description":"Genes having at least one occurence of the motif CTCCAAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-432 (v7.1 miRBase)."} {"geneset":"AAGCAAT_MIR137","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAGCAAT_MIR137","description":"Genes having at least one occurence of the motif AAGCAAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-137 (v7.1 miRBase)."} {"geneset":"ACCAAAG_MIR9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACCAAAG_MIR9","description":"Genes having at least one occurence of the motif ACCAAAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-9 (v7.1 miRBase)."} {"geneset":"TTTGTAG_MIR520D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTTGTAG_MIR520D","description":"Genes having at least one occurence of the motif TTTGTAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-520d* (v7.1 miRBase)."} {"geneset":"TGCCTTA_MIR124A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCCTTA_MIR124A","description":"Genes having at least one occurence of the motif TGCCTTA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-124a (v7.1 miRBase)."} {"geneset":"AACTGAC_MIR223","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AACTGAC_MIR223","description":"Genes having at least one occurence of the motif AACTGAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-223 (v7.1 miRBase)."} {"geneset":"AAAGACA_MIR511","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAAGACA_MIR511","description":"Genes having at least one occurence of the motif AAAGACA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-511 (v7.1 miRBase)."} {"geneset":"ATAAGCT_MIR21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATAAGCT_MIR21","description":"Genes having at least one occurence of the motif ATAAGCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-21 (v7.1 miRBase)."} {"geneset":"RACTNNRTTTNC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RACTNNRTTTNC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M66 RACTNNRTTTNC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TCTGATA_MIR361","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCTGATA_MIR361","description":"Genes having at least one occurence of the motif TCTGATA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-361 (v7.1 miRBase)."} {"geneset":"TACAATC_MIR508","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TACAATC_MIR508","description":"Genes having at least one occurence of the motif TACAATC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-508 (v7.1 miRBase)."} {"geneset":"ACTTTAT_MIR1425P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTTTAT_MIR1425P","description":"Genes having at least one occurence of the motif ACTTTAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-142-5p (v7.1 miRBase)."} {"geneset":"TTTGCAG_MIR518A2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTTGCAG_MIR518A2","description":"Genes having at least one occurence of the motif TTTGCAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-518a-2* (v7.1 miRBase)."} {"geneset":"AACATTC_MIR4093P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AACATTC_MIR4093P","description":"Genes having at least one occurence of the motif AACATTC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-409-3p (v7.1 miRBase)."} {"geneset":"ACAACCT_MIR453","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACAACCT_MIR453","description":"Genes having at least one occurence of the motif ACAACCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-453 (v7.1 miRBase)."} {"geneset":"GTGCCAA_MIR96","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGCCAA_MIR96","description":"Genes having at least one occurence of the motif GTGCCAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-96 (v7.1 miRBase)."} {"geneset":"TCATCTC_MIR143","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCATCTC_MIR143","description":"Genes having at least one occurence of the motif TCATCTC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-143 (v7.1 miRBase)."} {"geneset":"GAGCTGG_MIR337","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GAGCTGG_MIR337","description":"Genes having at least one occurence of the motif GAGCTGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-337 (v7.1 miRBase)."} {"geneset":"AGTCTAG_MIR151","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGTCTAG_MIR151","description":"Genes having at least one occurence of the motif AGTCTAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-151 (v7.1 miRBase)."} {"geneset":"RNCTGNYNRNCTGNY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RNCTGNYNRNCTGNY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M154 RNCTGNYNRNCTGNY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AGTCTTA_MIR499","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGTCTTA_MIR499","description":"Genes having at least one occurence of the motif AGTCTTA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-499 (v7.1 miRBase)."} {"geneset":"CCCAGAG_MIR326","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCCAGAG_MIR326","description":"Genes having at least one occurence of the motif CCCAGAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-326 (v7.1 miRBase)."} {"geneset":"GCTGAGT_MIR5125P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCTGAGT_MIR5125P","description":"Genes having at least one occurence of the motif GCTGAGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-512-5p (v7.1 miRBase)."} {"geneset":"ACCATTT_MIR522","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACCATTT_MIR522","description":"Genes having at least one occurence of the motif ACCATTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-522 (v7.1 miRBase)."} {"geneset":"AGCTCCT_MIR28","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGCTCCT_MIR28","description":"Genes having at least one occurence of the motif AGCTCCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-28 (v7.1 miRBase)."} {"geneset":"AGCGCAG_MIR191","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGCGCAG_MIR191","description":"Genes having at least one occurence of the motif AGCGCAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-191* (v7.1 miRBase)."} {"geneset":"ACTGCCT_MIR34B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTGCCT_MIR34B","description":"Genes having at least one occurence of the motif ACTGCCT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-34b (v7.1 miRBase)."} {"geneset":"GTTAAAG_MIR302B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTTAAAG_MIR302B","description":"Genes having at least one occurence of the motif GTTAAAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-302b* (v7.1 miRBase)."} {"geneset":"GACAATC_MIR219","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GACAATC_MIR219","description":"Genes having at least one occurence of the motif GACAATC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-219 (v7.1 miRBase)."} {"geneset":"CGCAAAA_MIR450","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CGCAAAA_MIR450","description":"Genes having at least one occurence of the motif CGCAAAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-450 (v7.1 miRBase)."} {"geneset":"RNGTGGGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RNGTGGGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M140 RNGTGGGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"AACTGGA_MIR145","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AACTGGA_MIR145","description":"Genes having at least one occurence of the motif AACTGGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-145 (v7.1 miRBase)."} {"geneset":"AAGCACT_MIR520F","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAGCACT_MIR520F","description":"Genes having at least one occurence of the motif AAGCACT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-520f (v7.1 miRBase)."} {"geneset":"AGGAGTG_MIR483","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGGAGTG_MIR483","description":"Genes having at least one occurence of the motif AGGAGTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-483 (v7.1 miRBase)."} {"geneset":"GTGTCAA_MIR514","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGTCAA_MIR514","description":"Genes having at least one occurence of the motif GTGTCAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-514 (v7.1 miRBase)."} {"geneset":"GCAAGGA_MIR502","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCAAGGA_MIR502","description":"Genes having at least one occurence of the motif GCAAGGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-502 (v7.1 miRBase)."} {"geneset":"AGGTGCA_MIR500","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGGTGCA_MIR500","description":"Genes having at least one occurence of the motif AGGTGCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-500 (v7.1 miRBase)."} {"geneset":"ACTGTAG_MIR139","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACTGTAG_MIR139","description":"Genes having at least one occurence of the motif ACTGTAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-139 (v7.1 miRBase)."} {"geneset":"GTGCAAA_MIR507","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGCAAA_MIR507","description":"Genes having at least one occurence of the motif GTGCAAA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-507 (v7.1 miRBase)."} {"geneset":"TGCTTTG_MIR330","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCTTTG_MIR330","description":"Genes having at least one occurence of the motif TGCTTTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-330 (v7.1 miRBase)."} {"geneset":"TTTTGAG_MIR373","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTTTGAG_MIR373","description":"Genes having at least one occurence of the motif TTTTGAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-373* (v7.1 miRBase)."} {"geneset":"RNTCANNRNNYNATTW_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RNTCANNRNNYNATTW_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M122 RNTCANNRNNYNATTW in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TAGAACC_MIR182","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAGAACC_MIR182","description":"Genes having at least one occurence of the motif TAGAACC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-182* (v7.1 miRBase)."} {"geneset":"GGGATGC_MIR3245P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGATGC_MIR3245P","description":"Genes having at least one occurence of the motif GGGATGC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-324-5p (v7.1 miRBase)."} {"geneset":"CCAGGGG_MIR331","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCAGGGG_MIR331","description":"Genes having at least one occurence of the motif CCAGGGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-331 (v7.1 miRBase)."} {"geneset":"ACCAATC_MIR509","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACCAATC_MIR509","description":"Genes having at least one occurence of the motif ACCAATC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-509 (v7.1 miRBase)."} {"geneset":"GGCACTT_MIR519E","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGCACTT_MIR519E","description":"Genes having at least one occurence of the motif GGCACTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-519e (v7.1 miRBase)."} {"geneset":"ATGTACA_MIR493","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGTACA_MIR493","description":"Genes having at least one occurence of the motif ATGTACA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-493 (v7.1 miRBase)."} {"geneset":"GCATTTG_MIR105","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCATTTG_MIR105","description":"Genes having at least one occurence of the motif GCATTTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-105 (v7.1 miRBase)."} {"geneset":"CAGTCAC_MIR134","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGTCAC_MIR134","description":"Genes having at least one occurence of the motif CAGTCAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-134 (v7.1 miRBase)."} {"geneset":"TCCAGAG_MIR518C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCCAGAG_MIR518C","description":"Genes having at least one occurence of the motif TCCAGAG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-518c* (v7.1 miRBase)."} {"geneset":"CACCAGC_MIR138","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CACCAGC_MIR138","description":"Genes having at least one occurence of the motif CACCAGC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-138 (v7.1 miRBase)."} {"geneset":"RRAGTTGT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RRAGTTGT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M129 RRAGTTGT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CAGCACT_MIR5123P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGCACT_MIR5123P","description":"Genes having at least one occurence of the motif CAGCACT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-512-3p (v7.1 miRBase)."} {"geneset":"GTACAGG_MIR486","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTACAGG_MIR486","description":"Genes having at least one occurence of the motif GTACAGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-486 (v7.1 miRBase)."} {"geneset":"GTTATAT_MIR410","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTTATAT_MIR410","description":"Genes having at least one occurence of the motif GTTATAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-410 (v7.1 miRBase)."} {"geneset":"GTCAGGA_MIR378","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTCAGGA_MIR378","description":"Genes having at least one occurence of the motif GTCAGGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-378 (v7.1 miRBase)."} {"geneset":"ACACTAC_MIR1423P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACACTAC_MIR1423P","description":"Genes having at least one occurence of the motif ACACTAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-142-3p (v7.1 miRBase)."} {"geneset":"ATTCTTT_MIR186","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATTCTTT_MIR186","description":"Genes having at least one occurence of the motif ATTCTTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-186 (v7.1 miRBase)."} {"geneset":"CTCTATG_MIR368","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTCTATG_MIR368","description":"Genes having at least one occurence of the motif CTCTATG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-368 (v7.1 miRBase)."} {"geneset":"ACCGAGC_MIR423","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ACCGAGC_MIR423","description":"Genes having at least one occurence of the motif ACCGAGC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-423 (v7.1 miRBase)."} {"geneset":"TGTGTGA_MIR377","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGTGTGA_MIR377","description":"Genes having at least one occurence of the motif TGTGTGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-377 (v7.1 miRBase)."} {"geneset":"ATCATGA_MIR433","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATCATGA_MIR433","description":"Genes having at least one occurence of the motif ATCATGA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-433 (v7.1 miRBase)."} {"geneset":"RRCCGTTA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RRCCGTTA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M146 RRCCGTTA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"CAGCAGG_MIR370","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGCAGG_MIR370","description":"Genes having at least one occurence of the motif CAGCAGG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-370 (v7.1 miRBase)."} {"geneset":"CTTTGCA_MIR527","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTTTGCA_MIR527","description":"Genes having at least one occurence of the motif CTTTGCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-527 (v7.1 miRBase)."} {"geneset":"GGTGTGT_MIR329","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGTGTGT_MIR329","description":"Genes having at least one occurence of the motif GGTGTGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-329 (v7.1 miRBase)."} {"geneset":"ATTACAT_MIR3803P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATTACAT_MIR3803P","description":"Genes having at least one occurence of the motif ATTACAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-380-3p (v7.1 miRBase)."} {"geneset":"CGTCTTA_MIR208","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CGTCTTA_MIR208","description":"Genes having at least one occurence of the motif CGTCTTA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-208 (v7.1 miRBase)."} {"geneset":"ATCTTGC_MIR31","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATCTTGC_MIR31","description":"Genes having at least one occurence of the motif ATCTTGC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-31 (v7.1 miRBase)."} {"geneset":"AAGGGAT_MIR188","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAGGGAT_MIR188","description":"Genes having at least one occurence of the motif AAGGGAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-188 (v7.1 miRBase)."} {"geneset":"TGCAAAC_MIR452","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCAAAC_MIR452","description":"Genes having at least one occurence of the motif TGCAAAC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-452 (v7.1 miRBase)."} {"geneset":"CAGCCTC_MIR4855P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGCCTC_MIR4855P","description":"Genes having at least one occurence of the motif CAGCCTC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-485-5p (v7.1 miRBase)."} {"geneset":"GTAAACC_MIR2995P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTAAACC_MIR2995P","description":"Genes having at least one occurence of the motif GTAAACC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-299-5p (v7.1 miRBase)."} {"geneset":"RTTTNNNYTGGM_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RTTTNNNYTGGM_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M107 RTTTNNNYTGGM in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"GGTAACC_MIR4095P","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGTAACC_MIR4095P","description":"Genes having at least one occurence of the motif GGTAACC in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-409-5p (v7.1 miRBase)."} {"geneset":"TAATAAT_MIR126","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAATAAT_MIR126","description":"Genes having at least one occurence of the motif TAATAAT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-126* (v7.1 miRBase)."} {"geneset":"ATGCACG_MIR517B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATGCACG_MIR517B","description":"Genes having at least one occurence of the motif ATGCACG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-517b (v7.1 miRBase)."} {"geneset":"CCACACA_MIR147","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCACACA_MIR147","description":"Genes having at least one occurence of the motif CCACACA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-147 (v7.1 miRBase)."} {"geneset":"TAATGTG_MIR323","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAATGTG_MIR323","description":"Genes having at least one occurence of the motif TAATGTG in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-323 (v7.1 miRBase)."} {"geneset":"TTCCGTT_MIR191","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTCCGTT_MIR191","description":"Genes having at least one occurence of the motif TTCCGTT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-191 (v7.1 miRBase)."} {"geneset":"AGTGCGT_MIR521","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AGTGCGT_MIR521","description":"Genes having at least one occurence of the motif AGTGCGT in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-521 (v7.1 miRBase)."} {"geneset":"CAATGCA_MIR33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAATGCA_MIR33","description":"Genes having at least one occurence of the motif CAATGCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-33 (v7.1 miRBase)."} {"geneset":"GTAGGCA_MIR189","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTAGGCA_MIR189","description":"Genes having at least one occurence of the motif GTAGGCA in their 3' untranslated region. The motif represents putative target (that is, seed match) of human mature miRNA hsa-miR-189 (v7.1 miRBase)."} {"geneset":"RYAAAKNNNNNNTTGW_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RYAAAKNNNNNNTTGW_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M151 RYAAAKNNNNNNTTGW in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"RYCACNNRNNRNCAG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RYCACNNRNNRNCAG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M128 RYCACNNRNNRNCAG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"RYTAAWNNNTGAY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RYTAAWNNNTGAY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M133 RYTAAWNNNTGAY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"RYTGCNWTGGNR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RYTGCNWTGGNR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M87 RYTGCNWTGGNR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"SMTTTTGT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SMTTTTGT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M62 SMTTTTGT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"SNACANNNYSYAGA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SNACANNNYSYAGA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M80 SNACANNNYSYAGA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"SYATTGTG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SYATTGTG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M71 SYATTGTG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TAANNYSGCG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAANNYSGCG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M162 TAANNYSGCG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TAAYNRNNTCC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAAYNRNNTCC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M136 TAAYNRNNTCC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TCCATTKW_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCCATTKW_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M132 TCCATTKW in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TCCCRNNRTGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCCCRNNRTGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M39 TCCCRNNRTGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TGACATY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGACATY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M42 TGACATY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TGCGCANK_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCGCANK_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M22 TGCGCANK in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TGCTGAY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCTGAY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M92 TGCTGAY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TGGNNNNNNKCCAR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGGNNNNNNKCCAR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M27 TGGNNNNNNKCCAR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TGTYNNNNNRGCARM_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGTYNNNNNRGCARM_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M117 TGTYNNNNNRGCARM in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TMTCGCGANR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TMTCGCGANR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M8 TMTCGCGANR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TNCATNTCCYR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TNCATNTCCYR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M75 TNCATNTCCYR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TTANTCA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTANTCA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M64 TTANTCA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TTANWNANTGGM_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTANWNANTGGM_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M161 TTANWNANTGGM in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TTCYRGAA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTCYRGAA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M72 TTCYRGAA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"TTTNNANAGCYR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTTNNANAGCYR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M169 TTTNNANAGCYR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"WCAANNNYCAG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WCAANNNYCAG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M152 WCAANNNYCAG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"WCTCNATGGY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WCTCNATGGY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M59 WCTCNATGGY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"WGTTNNNNNAAA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WGTTNNNNNAAA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M155 WGTTNNNNNAAA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"WTGAAAT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WTGAAAT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M174 WTGAAAT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"WTTGKCTG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WTTGKCTG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M46 WTTGKCTG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"WWTAAGGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WWTAAGGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M127 WWTAAGGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"WYAAANNRNNNGCG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WYAAANNRNNNGCG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M126 WYAAANNRNNNGCG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YAATNANRNNNCAG_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAATNANRNNNCAG_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M147 YAATNANRNNNCAG in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YAATNRNNNYNATT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAATNRNNNYNATT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M90 YAATNRNNNYNATT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YATTNATC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YATTNATC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M97 YATTNATC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YCATTAA_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YCATTAA_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M58 YCATTAA in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YGACNNYACAR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YGACNNYACAR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M149 YGACNNYACAR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YGCANTGCR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YGCANTGCR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M96 YGCANTGCR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YGCGYRCGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YGCGYRCGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M30 YGCGYRCGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YGTCCTTGR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YGTCCTTGR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M109 YGTCCTTGR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YKACATTT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YKACATTT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M145 YKACATTT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YNGTTNNNATT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YNGTTNNNATT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M170 YNGTTNNNATT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YNTTTNNNANGCARM_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YNTTTNNNANGCARM_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M166 YNTTTNNNANGCARM in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YRCCAKNNGNCGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YRCCAKNNGNCGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M156 YRCCAKNNGNCGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YRTCANNRCGC_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YRTCANNRCGC_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M115 YRTCANNRCGC in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YTAAYNGCT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YTAAYNGCT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M168 YTAAYNGCT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YTCCCRNNAGGY_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YTCCCRNNAGGY_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M114 YTCCCRNNAGGY in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YTTCCNNNGGAMR_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YTTCCNNNGGAMR_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M150 YTTCCNNNGGAMR in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YWATTWNNRGCT_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YWATTWNNRGCT_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M173 YWATTWNNRGCT in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"YYCATTCAWW_UNKNOWN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YYCATTCAWW_UNKNOWN","description":"Genes having at least one occurence of the highly conserved motif M52 YYCATTCAWW in the region spanning up to 4 kb around their transcription start sites. The motif does not match any known transcription factor binding site (v7.4 TRANSFAC)."} {"geneset":"RACCACAR_AML_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RACCACAR_AML_Q6","description":"Genes having at least one occurence of the highly conserved motif M111 RACCACAR sites. The motif matches transcription factor binding site V$AML_Q6 (v7.4 TRANSFAC)."} {"geneset":"TGANTCA_AP1_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGANTCA_AP1_C","description":"Genes having at least one occurence of the highly conserved motif M7 TGANTCA sites. The motif matches transcription factor binding site V$AP1_C (v7.4 TRANSFAC)."} {"geneset":"CAGCTG_AP4_Q5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGCTG_AP4_Q5","description":"Genes having at least one occurence of the highly conserved motif M15 CAGCTG sites. The motif matches transcription factor binding site V$AP4_Q5 (v7.4 TRANSFAC)."} {"geneset":"CAGGTA_AREB6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGGTA_AREB6_01","description":"Genes having at least one occurence of the highly conserved motif M76 CAGGTA sites. The motif matches transcription factor binding site V$AREB6_01 (v7.4 TRANSFAC)."} {"geneset":"TGACGTCA_ATF3_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGACGTCA_ATF3_Q6","description":"Genes having at least one occurence of the highly conserved motif M14 TGACGTCA sites. The motif matches transcription factor binding site V$ATF3_Q6 (v7.4 TRANSFAC)."} {"geneset":"TGAYRTCA_ATF3_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGAYRTCA_ATF3_Q6","description":"Genes having at least one occurence of the highly conserved motif M9 TGAYRTCA sites. The motif matches transcription factor binding site V$ATF3_Q6 (v7.4 TRANSFAC)."} {"geneset":"TTGCWCAAY_CEBPB_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTGCWCAAY_CEBPB_02","description":"Genes having at least one occurence of the highly conserved motif M172 TTGCWCAAY sites. The motif matches transcription factor binding site V$CEBPB_02 (v7.4 TRANSFAC)."} {"geneset":"TAATTA_CHX10_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAATTA_CHX10_01","description":"Genes having at least one occurence of the highly conserved motif M23 TAATTA sites. The motif matches transcription factor binding site V$CHX10_01 (v7.4 TRANSFAC)."} {"geneset":"CAGGTG_E12_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAGGTG_E12_Q6","description":"Genes having at least one occurence of the highly conserved motif M12 CAGGTG sites. The motif matches transcription factor binding site V$E12_Q6 (v7.4 TRANSFAC)."} {"geneset":"SGCGSSAAA_E2F1DP2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SGCGSSAAA_E2F1DP2_01","description":"Genes having at least one occurence of the highly conserved motif M69 SGCGSSAAA sites. The motif matches transcription factor binding site V$E2F1DP2_01 (v7.4 TRANSFAC)."} {"geneset":"TTAYRTAA_E4BP4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTAYRTAA_E4BP4_01","description":"Genes having at least one occurence of the highly conserved motif M26 TTAYRTAA sites. The motif matches transcription factor binding site V$E4BP4_01 (v7.4 TRANSFAC)."} {"geneset":"GTGACGY_E4F1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GTGACGY_E4F1_Q6","description":"Genes having at least one occurence of the highly conserved motif M20 GTGACGY sites. The motif matches transcription factor binding site V$E4F1_Q6 (v7.4 TRANSFAC)."} {"geneset":"SCGGAAGY_ELK1_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SCGGAAGY_ELK1_02","description":"Genes having at least one occurence of the highly conserved motif M3 SCGGAAGY sites. The motif matches transcription factor binding site V$ELK1_02 (v7.4 TRANSFAC)."} {"geneset":"TGACCTY_ERR1_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGACCTY_ERR1_Q2","description":"Genes having at least one occurence of the highly conserved motif M25 TGACCTY sites. The motif matches transcription factor binding site V$ERR1_Q2 (v7.4 TRANSFAC)."} {"geneset":"RYTTCCTG_ETS2_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RYTTCCTG_ETS2_B","description":"Genes having at least one occurence of the highly conserved motif M16 RYTTCCTG sites. The motif matches transcription factor binding site V$ETS2_B (v7.4 TRANSFAC)."} {"geneset":"TTGTTT_FOXO4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTGTTT_FOXO4_01","description":"Genes having at least one occurence of the highly conserved motif M60 TTGTTT sites. The motif matches transcription factor binding site V$FOXO4_01 (v7.4 TRANSFAC)."} {"geneset":"RTAAACA_FREAC2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RTAAACA_FREAC2_01","description":"Genes having at least one occurence of the highly conserved motif M36 RTAAACA sites. The motif matches transcription factor binding site V$FREAC2_01 (v7.4 TRANSFAC)."} {"geneset":"MGGAAGTG_GABP_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MGGAAGTG_GABP_B","description":"Genes having at least one occurence of the highly conserved motif M11 MGGAAGTG sites. The motif matches transcription factor binding site V$GABP_B (v7.4 TRANSFAC)."} {"geneset":"GATAAGR_GATA_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATAAGR_GATA_C","description":"Genes having at least one occurence of the highly conserved motif M131 GATAAGR sites. The motif matches transcription factor binding site V$GATA_C (v7.4 TRANSFAC)."} {"geneset":"TGATTTRY_GFI1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGATTTRY_GFI1_01","description":"Genes having at least one occurence of the highly conserved motif M94 TGATTTRY sites. The motif matches transcription factor binding site V$GFI1_01 (v7.4 TRANSFAC)."} {"geneset":"AAAYWAACM_HFH4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AAAYWAACM_HFH4_01","description":"Genes having at least one occurence of the highly conserved motif M139 AAAYWAACM sites. The motif matches transcription factor binding site V$HFH4_01 (v7.4 TRANSFAC)."} {"geneset":"RGTTAMWNATT_HNF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RGTTAMWNATT_HNF1_01","description":"Genes having at least one occurence of the highly conserved motif M84 RGTTAMWNATT sites. The motif matches transcription factor binding site V$HNF1_01 (v7.4 TRANSFAC)."} {"geneset":"TGTTTGY_HNF3_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGTTTGY_HNF3_Q6","description":"Genes having at least one occurence of the highly conserved motif M83 TGTTTGY sites. The motif matches transcription factor binding site V$HNF3_Q6 (v7.4 TRANSFAC)."} {"geneset":"TTCNRGNNNNTTC_HSF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTCNRGNNNNTTC_HSF_Q6","description":"Genes having at least one occurence of the highly conserved motif M141 TTCNRGNNNNTTC sites. The motif matches transcription factor binding site V$HSF_Q6 (v7.4 TRANSFAC)."} {"geneset":"RGAANNTTC_HSF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RGAANNTTC_HSF1_01","description":"Genes having at least one occurence of the highly conserved motif M68 RGAANNTTC sites. The motif matches transcription factor binding site V$HSF1_01 (v7.4 TRANSFAC)."} {"geneset":"STTTCRNTTT_IRF_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STTTCRNTTT_IRF_Q6","description":"Genes having at least one occurence of the highly conserved motif M85 STTTCRNTTT sites. The motif matches transcription factor binding site V$IRF_Q6 (v7.4 TRANSFAC)."} {"geneset":"CTTTGA_LEF1_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTTTGA_LEF1_Q2","description":"Genes having at least one occurence of the highly conserved motif M73 CTTTGA sites. The motif matches transcription factor binding site V$LEF1_Q2 (v7.4 TRANSFAC)."} {"geneset":"CTTTGT_LEF1_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTTTGT_LEF1_Q2","description":"Genes having at least one occurence of the highly conserved motif M13 CTTTGT sites. The motif matches transcription factor binding site V$LEF1_Q2 (v7.4 TRANSFAC)."} {"geneset":"YTAATTAA_LHX3_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YTAATTAA_LHX3_01","description":"Genes having at least one occurence of the highly conserved motif M61 YTAATTAA sites. The motif matches transcription factor binding site V$LHX3_01 (v7.4 TRANSFAC)."} {"geneset":"GGGAGGRR_MAZ_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGAGGRR_MAZ_Q6","description":"Genes having at least one occurence of the highly conserved motif M24 GGGAGGRR sites. The motif matches transcription factor binding site V$MAZ_Q6 (v7.4 TRANSFAC)."} {"geneset":"YTATTTTNR_MEF2_02","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YTATTTTNR_MEF2_02","description":"Genes having at least one occurence of the highly conserved motif M33 YTATTTTNR sites. The motif matches transcription factor binding site V$MEF2_02 (v7.4 TRANSFAC)."} {"geneset":"TGACAGNY_MEIS1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGACAGNY_MEIS1_01","description":"Genes having at least one occurence of the highly conserved motif M41 TGACAGNY sites. The motif matches transcription factor binding site V$MEIS1_01 (v7.4 TRANSFAC)."} {"geneset":"RYTGCNNRGNAAC_MIF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RYTGCNNRGNAAC_MIF1_01","description":"Genes having at least one occurence of the highly conserved motif M53 RYTGCNNRGNAAC sites. The motif matches transcription factor binding site V$MIF1_01 (v7.4 TRANSFAC)."} {"geneset":"CACGTG_MYC_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CACGTG_MYC_Q2","description":"Genes having at least one occurence of the highly conserved motif M2 CACGTG sites. The motif matches transcription factor binding site V$MYC_Q2 (v7.4 TRANSFAC)."} {"geneset":"GCANCTGNY_MYOD_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCANCTGNY_MYOD_Q6","description":"Genes having at least one occurence of the highly conserved motif M35 GCANCTGNY sites. The motif matches transcription factor binding site V$MYOD_Q6 (v7.4 TRANSFAC)."} {"geneset":"TGCCAAR_NF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGCCAAR_NF1_Q6","description":"Genes having at least one occurence of the highly conserved motif M47 TGCCAAR sites. The motif matches transcription factor binding site V$NF1_Q6 (v7.4 TRANSFAC)."} {"geneset":"TGGAAA_NFAT_Q4_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGGAAA_NFAT_Q4_01","description":"Genes having at least one occurence of the highly conserved motif M55 TGGAAA sites. The motif matches transcription factor binding site V$NFAT_Q4_01 (v7.4 TRANSFAC)."} {"geneset":"TGASTMAGC_NFE2_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGASTMAGC_NFE2_01","description":"Genes having at least one occurence of the highly conserved motif M32 TGASTMAGC sites. The motif matches transcription factor binding site V$NFE2_01 (v7.4 TRANSFAC)."} {"geneset":"GGGNNTTTCC_NFKB_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGNNTTTCC_NFKB_Q6_01","description":"Genes having at least one occurence of the highly conserved motif M86 GGGNNTTTCC sites. The motif matches transcription factor binding site V$NFKB_Q6_01 (v7.4 TRANSFAC)."} {"geneset":"GATTGGY_NFY_Q6_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GATTGGY_NFY_Q6_01","description":"Genes having at least one occurence of the highly conserved motif M5 GATTGGY sites. The motif matches transcription factor binding site V$NFY_Q6_01 (v7.4 TRANSFAC)."} {"geneset":"RCGCANGCGY_NRF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RCGCANGCGY_NRF1_Q6","description":"Genes having at least one occurence of the highly conserved motif M1 RCGCANGCGY sites. The motif matches transcription factor binding site V$NRF1_Q6 (v7.4 TRANSFAC)."} {"geneset":"YATGNWAAT_OCT_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YATGNWAAT_OCT_C","description":"Genes having at least one occurence of the highly conserved motif M44 YATGNWAAT sites. The motif matches transcription factor binding site V$OCT_C (v7.4 TRANSFAC)."} {"geneset":"CCCNNGGGAR_OLF1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCCNNGGGAR_OLF1_01","description":"Genes having at least one occurence of the highly conserved motif M130 CCCNNGGGAR sites. The motif matches transcription factor binding site V$OLF1_01 (v7.4 TRANSFAC)."} {"geneset":"CGTSACG_PAX3_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CGTSACG_PAX3_B","description":"Genes having at least one occurence of the highly conserved motif M70 CGTSACG sites. The motif matches transcription factor binding site V$PAX3_B (v7.4 TRANSFAC)."} {"geneset":"GGGTGGRR_PAX4_03","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGTGGRR_PAX4_03","description":"Genes having at least one occurence of the highly conserved motif M56 GGGTGGRR sites. The motif matches transcription factor binding site V$PAX4_03 (v7.4 TRANSFAC)."} {"geneset":"GGATTA_PITX2_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGATTA_PITX2_Q2","description":"Genes having at least one occurence of the highly conserved motif M93 GGATTA sites. The motif matches transcription factor binding site V$PITX2_Q2 (v7.4 TRANSFAC)."} {"geneset":"RGAGGAARY_PU1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RGAGGAARY_PU1_Q6","description":"Genes having at least one occurence of the highly conserved motif M50 RGAGGAARY sites. The motif matches transcription factor binding site V$PU1_Q6 (v7.4 TRANSFAC)."} {"geneset":"CTAWWWATA_RSRFC4_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTAWWWATA_RSRFC4_Q2","description":"Genes having at least one occurence of the highly conserved motif M28 CTAWWWATA sites. The motif matches transcription factor binding site V$RSRFC4_Q2 (v7.4 TRANSFAC)."} {"geneset":"TAAWWATAG_RSRFC4_Q2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TAAWWATAG_RSRFC4_Q2","description":"Genes having at least one occurence of the highly conserved motif M54 TAAWWATAG sites. The motif matches transcription factor binding site V$RSRFC4_Q2 (v7.4 TRANSFAC)."} {"geneset":"TGACCTTG_SF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGACCTTG_SF1_Q6","description":"Genes having at least one occurence of the highly conserved motif M38 TGACCTTG sites. The motif matches transcription factor binding site V$SF1_Q6 (v7.4 TRANSFAC)."} {"geneset":"CATTGTYY_SOX9_B1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CATTGTYY_SOX9_B1","description":"Genes having at least one occurence of the highly conserved motif M49 CATTGTYY sites. The motif matches transcription factor binding site V$SOX9_B1 (v7.4 TRANSFAC)."} {"geneset":"GGGCGGR_SP1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GGGCGGR_SP1_Q6","description":"Genes having at least one occurence of the highly conserved motif M6 GGGCGGR sites. The motif matches transcription factor binding site V$SP1_Q6 (v7.4 TRANSFAC)."} {"geneset":"TCANNTGAY_SREBP1_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TCANNTGAY_SREBP1_01","description":"Genes having at least one occurence of the highly conserved motif M18 TCANNTGAY sites. The motif matches transcription factor binding site V$SREBP1_01 (v7.4 TRANSFAC)."} {"geneset":"CCAWWNAAGG_SRF_Q4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CCAWWNAAGG_SRF_Q4","description":"Genes having at least one occurence of the highly conserved motif M121 CCAWWNAAGG sites. The motif matches transcription factor binding site V$SRF_Q4 (v7.4 TRANSFAC)."} {"geneset":"TTCYNRGAA_STAT5B_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TTCYNRGAA_STAT5B_01","description":"Genes having at least one occurence of the highly conserved motif M40 TTCYNRGAA sites. The motif matches transcription factor binding site V$STAT5B_01 (v7.4 TRANSFAC)."} {"geneset":"TATAAA_TATA_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TATAAA_TATA_01","description":"Genes having at least one occurence of the highly conserved motif M51 TATAAA sites. The motif matches transcription factor binding site V$TATA_01 (v7.4 TRANSFAC)."} {"geneset":"TGANNYRGCA_TCF11MAFG_01","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGANNYRGCA_TCF11MAFG_01","description":"Genes having at least one occurence of the highly conserved motif M67 TGANNYRGCA sites. The motif matches transcription factor binding site V$TCF11MAFG_01 (v7.4 TRANSFAC)."} {"geneset":"WGGAATGY_TEF1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WGGAATGY_TEF1_Q6","description":"Genes having at least one occurence of the highly conserved motif M79 WGGAATGY sites. The motif matches transcription factor binding site V$TEF1_Q6 (v7.4 TRANSFAC)."} {"geneset":"GCCATNTTG_YY1_Q6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCCATNTTG_YY1_Q6","description":"Genes having at least one occurence of the highly conserved motif M10 GCCATNTTG sites. The motif matches transcription factor binding site V$YY1_Q6 (v7.4 TRANSFAC)."} {"geneset":"MORF_ATRX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ATRX","description":"Neighborhood of ATRX"} {"geneset":"MORF_ATOX1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ATOX1","description":"Neighborhood of ATOX1"} {"geneset":"MORF_BCL2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BCL2","description":"Neighborhood of BCL2"} {"geneset":"MORF_BNIP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BNIP1","description":"Neighborhood of BNIP1"} {"geneset":"MORF_BAG5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BAG5","description":"Neighborhood of BAG5"} {"geneset":"MORF_BCL2L11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BCL2L11","description":"Neighborhood of BCL2L11"} {"geneset":"MORF_BECN1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BECN1","description":"Neighborhood of BECN1"} {"geneset":"MORF_BRCA1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BRCA1","description":"Neighborhood of BRCA1"} {"geneset":"MORF_BUB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BUB1","description":"Neighborhood of BUB1"} {"geneset":"MORF_BUB3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BUB3","description":"Neighborhood of BUB3"} {"geneset":"MORF_CTBP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CTBP1","description":"Neighborhood of CTBP1"} {"geneset":"MORF_CCNF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CCNF","description":"Neighborhood of CCNF"} {"geneset":"MORF_CCNI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CCNI","description":"Neighborhood of CCNI"} {"geneset":"MORF_DNMT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DNMT1","description":"Neighborhood of DNMT1"} {"geneset":"MORF_ERCC2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ERCC2","description":"Neighborhood of ERCC2"} {"geneset":"MORF_ESPL1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ESPL1","description":"Neighborhood of ESPL1"} {"geneset":"MORF_FDXR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FDXR","description":"Neighborhood of FDXR"} {"geneset":"MORF_FEN1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FEN1","description":"Neighborhood of FEN1"} {"geneset":"MORF_GPX4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_GPX4","description":"Neighborhood of GPX4"} {"geneset":"MORF_HAT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_HAT1","description":"Neighborhood of HAT1"} {"geneset":"MORF_HDAC1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_HDAC1","description":"Neighborhood of HDAC1"} {"geneset":"MORF_HDAC2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_HDAC2","description":"Neighborhood of HDAC2"} {"geneset":"MORF_MDM2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MDM2","description":"Neighborhood of MDM2"} {"geneset":"MORF_MT4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MT4","description":"Neighborhood of MT4"} {"geneset":"MORF_MSH2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MSH2","description":"Neighborhood of MSH2"} {"geneset":"MORF_MSH3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MSH3","description":"Neighborhood of MSH3"} {"geneset":"MORF_NF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_NF1","description":"Neighborhood of NF1"} {"geneset":"MORF_PRDX3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRDX3","description":"Neighborhood of PRDX3"} {"geneset":"MORF_PCNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PCNA","description":"Neighborhood of PCNA"} {"geneset":"MORF_PSMC1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PSMC1","description":"Neighborhood of PSMC1"} {"geneset":"MORF_PSMC2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PSMC2","description":"Neighborhood of PSMC2"} {"geneset":"MORF_PSMF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PSMF1","description":"Neighborhood of PSMF1"} {"geneset":"MORF_PRKDC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRKDC","description":"Neighborhood of PRKDC"} {"geneset":"MORF_RAD21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAD21","description":"Neighborhood of RAD21"} {"geneset":"MORF_RAD23A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAD23A","description":"Neighborhood of RAD23A"} {"geneset":"MORF_RAD23B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAD23B","description":"Neighborhood of RAD23B"} {"geneset":"MORF_RAD51L3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAD51L3","description":"Neighborhood of RAD51L3"} {"geneset":"MORF_RAD54L","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAD54L","description":"Neighborhood of RAD54L"} {"geneset":"MORF_RFC1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RFC1","description":"Neighborhood of RFC1"} {"geneset":"MORF_RFC4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RFC4","description":"Neighborhood of RFC4"} {"geneset":"MORF_RFC5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RFC5","description":"Neighborhood of RFC5"} {"geneset":"MORF_RPA1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RPA1","description":"Neighborhood of RPA1"} {"geneset":"MORF_RPA2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RPA2","description":"Neighborhood of RPA2"} {"geneset":"MORF_RRM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RRM1","description":"Neighborhood of RRM1"} {"geneset":"MORF_STK17A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_STK17A","description":"Neighborhood of STK17A"} {"geneset":"MORF_SMC1L1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SMC1L1","description":"Neighborhood of SMC1L1"} {"geneset":"MORF_SP3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SP3","description":"Neighborhood of SP3"} {"geneset":"MORF_SOD1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SOD1","description":"Neighborhood of SOD1"} {"geneset":"MORF_TERF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TERF1","description":"Neighborhood of TERF1"} {"geneset":"MORF_TERF2IP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TERF2IP","description":"Neighborhood of TERF2IP"} {"geneset":"MORF_TFDP2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TFDP2","description":"Neighborhood of TFDP2"} {"geneset":"MORF_UNG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_UNG","description":"Neighborhood of UNG"} {"geneset":"MORF_MYC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MYC","description":"Neighborhood of MYC"} {"geneset":"MORF_XPC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_XPC","description":"Neighborhood of XPC"} {"geneset":"MORF_XRCC5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_XRCC5","description":"Neighborhood of XRCC5"} {"geneset":"MORF_AATF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_AATF","description":"Neighborhood of AATF"} {"geneset":"MORF_ACP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ACP1","description":"Neighborhood of ACP1"} {"geneset":"MORF_ACTG1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ACTG1","description":"Neighborhood of ACTG1"} {"geneset":"MORF_ANP32B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ANP32B","description":"Neighborhood of ANP32B"} {"geneset":"MORF_AP2M1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_AP2M1","description":"Neighborhood of AP2M1"} {"geneset":"MORF_AP3D1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_AP3D1","description":"Neighborhood of AP3D1"} {"geneset":"MORF_ARAF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ARAF1","description":"Neighborhood of ARAF1"} {"geneset":"MORF_ARL3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ARL3","description":"Neighborhood of ARL3"} {"geneset":"MORF_ATF2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ATF2","description":"Neighborhood of ATF2"} {"geneset":"MORF_BMI1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BMI1","description":"Neighborhood of BMI1"} {"geneset":"MORF_BMPR2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BMPR2","description":"Neighborhood of BMPR2"} {"geneset":"MORF_BUB1B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BUB1B","description":"Neighborhood of BUB1B"} {"geneset":"MORF_CAMK4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CAMK4","description":"Neighborhood of CAMK4"} {"geneset":"MORF_CASP10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CASP10","description":"Neighborhood of CASP10"} {"geneset":"MORF_CASP2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CASP2","description":"Neighborhood of CASP2"} {"geneset":"MORF_CD8A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CD8A","description":"Neighborhood of CD8A"} {"geneset":"MORF_CDC10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CDC10","description":"Neighborhood of CDC10"} {"geneset":"MORF_CDC16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CDC16","description":"Neighborhood of CDC16"} {"geneset":"MORF_CDC2L5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CDC2L5","description":"Neighborhood of CDC2L5"} {"geneset":"MORF_CDH4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CDH4","description":"Neighborhood of CDH4"} {"geneset":"MORF_CDK2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CDK2","description":"Neighborhood of CDK2"} {"geneset":"MORF_CNTN1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CNTN1","description":"Neighborhood of CNTN1"} {"geneset":"MORF_CSNK1D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CSNK1D","description":"Neighborhood of CSNK1D"} {"geneset":"MORF_CSNK2B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CSNK2B","description":"Neighborhood of CSNK2B"} {"geneset":"MORF_CTSB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CTSB","description":"Neighborhood of CTSB"} {"geneset":"MORF_CUL1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CUL1","description":"Neighborhood of CUL1"} {"geneset":"MORF_DAP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DAP","description":"Neighborhood of DAP"} {"geneset":"MORF_DAP3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DAP3","description":"Neighborhood of DAP3"} {"geneset":"MORF_DCC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DCC","description":"Neighborhood of DCC"} {"geneset":"MORF_DDB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DDB1","description":"Neighborhood of DDB1"} {"geneset":"MORF_DDX11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DDX11","description":"Neighborhood of DDX11"} {"geneset":"MORF_DEAF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DEAF1","description":"Neighborhood of DEAF1"} {"geneset":"MORF_DEK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DEK","description":"Neighborhood of DEK"} {"geneset":"MORF_DMPK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DMPK","description":"Neighborhood of DMPK"} {"geneset":"MORF_EI24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_EI24","description":"Neighborhood of EI24"} {"geneset":"MORF_EIF3S2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_EIF3S2","description":"Neighborhood of EIF3S2"} {"geneset":"MORF_EIF3S6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_EIF3S6","description":"Neighborhood of EIF3S6"} {"geneset":"MORF_EIF4A2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_EIF4A2","description":"Neighborhood of EIF4A2"} {"geneset":"MORF_EIF4E","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_EIF4E","description":"Neighborhood of EIF4E"} {"geneset":"MORF_EPHA7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_EPHA7","description":"Neighborhood of EPHA7"} {"geneset":"MORF_ERCC4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ERCC4","description":"Neighborhood of ERCC4"} {"geneset":"MORF_ERH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ERH","description":"Neighborhood of ERH"} {"geneset":"MORF_ESR1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ESR1","description":"Neighborhood of ESR1"} {"geneset":"MORF_ETV3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ETV3","description":"Neighborhood of ETV3"} {"geneset":"MORF_FANCG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FANCG","description":"Neighborhood of FANCG"} {"geneset":"MORF_FBL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FBL","description":"Neighborhood of FBL"} {"geneset":"MORF_FLT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FLT1","description":"Neighborhood of FLT1"} {"geneset":"MORF_FOSL1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FOSL1","description":"Neighborhood of FOSL1"} {"geneset":"MORF_FRK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FRK","description":"Neighborhood of FRK"} {"geneset":"MORF_FSHR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FSHR","description":"Neighborhood of FSHR"} {"geneset":"MORF_G22P1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_G22P1","description":"Neighborhood of G22P1"} {"geneset":"MORF_GMPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_GMPS","description":"Neighborhood of GMPS"} {"geneset":"MORF_GNB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_GNB1","description":"Neighborhood of GNB1"} {"geneset":"MORF_GSPT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_GSPT1","description":"Neighborhood of GSPT1"} {"geneset":"MORF_HEAB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_HEAB","description":"Neighborhood of HEAB"} {"geneset":"MORF_IFNA1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IFNA1","description":"Neighborhood of IFNA1"} {"geneset":"MORF_IKBKG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IKBKG","description":"Neighborhood of IKBKG"} {"geneset":"MORF_IL13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IL13","description":"Neighborhood of IL13"} {"geneset":"MORF_IL16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IL16","description":"Neighborhood of IL16"} {"geneset":"MORF_IL4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IL4","description":"Neighborhood of IL4"} {"geneset":"MORF_IL9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IL9","description":"Neighborhood of IL9"} {"geneset":"MORF_ITGA2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ITGA2","description":"Neighborhood of ITGA2"} {"geneset":"MORF_JAG1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_JAG1","description":"Neighborhood of JAG1"} {"geneset":"MORF_JAK3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_JAK3","description":"Neighborhood of JAK3"} {"geneset":"MORF_JUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_JUND","description":"Neighborhood of JUND"} {"geneset":"MORF_KDR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_KDR","description":"Neighborhood of KDR"} {"geneset":"MORF_LCAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_LCAT","description":"Neighborhood of LCAT"} {"geneset":"MORF_LMO1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_LMO1","description":"Neighborhood of LMO1"} {"geneset":"MORF_LTK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_LTK","description":"Neighborhood of LTK"} {"geneset":"MORF_MAGEA8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MAGEA8","description":"Neighborhood of MAGEA8"} {"geneset":"MORF_MAGEA9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MAGEA9","description":"Neighborhood of MAGEA9"} {"geneset":"MORF_MAP2K2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MAP2K2","description":"Neighborhood of MAP2K2"} {"geneset":"MORF_MAP2K7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MAP2K7","description":"Neighborhood of MAP2K7"} {"geneset":"MORF_MAP3K14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MAP3K14","description":"Neighborhood of MAP3K14"} {"geneset":"MORF_MBD4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MBD4","description":"Neighborhood of MBD4"} {"geneset":"MORF_MLLT10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MLLT10","description":"Neighborhood of MLLT10"} {"geneset":"MORF_MTA1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MTA1","description":"Neighborhood of MTA1"} {"geneset":"MORF_MYL3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MYL3","description":"Neighborhood of MYL3"} {"geneset":"MORF_MYST2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_MYST2","description":"Neighborhood of MYST2"} {"geneset":"MORF_NME2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_NME2","description":"Neighborhood of NME2"} {"geneset":"MORF_NOS2A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_NOS2A","description":"Neighborhood of NOS2A"} {"geneset":"MORF_NPM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_NPM1","description":"Neighborhood of NPM1"} {"geneset":"MORF_ORC1L","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ORC1L","description":"Neighborhood of ORC1L"} {"geneset":"MORF_PAPSS1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PAPSS1","description":"Neighborhood of PAPSS1"} {"geneset":"MORF_PAX7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PAX7","description":"Neighborhood of PAX7"} {"geneset":"MORF_PDCD1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PDCD1","description":"Neighborhood of PDCD1"} {"geneset":"MORF_PDPK1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PDPK1","description":"Neighborhood of PDPK1"} {"geneset":"MORF_PHB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PHB","description":"Neighborhood of PHB"} {"geneset":"MORF_PML","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PML","description":"Neighborhood of PML"} {"geneset":"MORF_PPP1CA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP1CA","description":"Neighborhood of PPP1CA"} {"geneset":"MORF_PPP1CC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP1CC","description":"Neighborhood of PPP1CC"} {"geneset":"MORF_PPP2CA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP2CA","description":"Neighborhood of PPP2CA"} {"geneset":"MORF_PPP2R4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP2R4","description":"Neighborhood of PPP2R4"} {"geneset":"MORF_PPP2R5B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP2R5B","description":"Neighborhood of PPP2R5B"} {"geneset":"MORF_PPP2R5E","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP2R5E","description":"Neighborhood of PPP2R5E"} {"geneset":"MORF_PPP5C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP5C","description":"Neighborhood of PPP5C"} {"geneset":"MORF_PPP6C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PPP6C","description":"Neighborhood of PPP6C"} {"geneset":"MORF_PRKACA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRKACA","description":"Neighborhood of PRKACA"} {"geneset":"MORF_PRKAG1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRKAG1","description":"Neighborhood of PRKAG1"} {"geneset":"MORF_PRKAR1A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRKAR1A","description":"Neighborhood of PRKAR1A"} {"geneset":"MORF_PRKCA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PRKCA","description":"Neighborhood of PRKCA"} {"geneset":"MORF_PTEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PTEN","description":"Neighborhood of PTEN"} {"geneset":"MORF_PTPN11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PTPN11","description":"Neighborhood of PTPN11"} {"geneset":"MORF_PTPN9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PTPN9","description":"Neighborhood of PTPN9"} {"geneset":"MORF_PTPRB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PTPRB","description":"Neighborhood of PTPRB"} {"geneset":"MORF_PTPRR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PTPRR","description":"Neighborhood of PTPRR"} {"geneset":"MORF_RAB11A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAB11A","description":"Neighborhood of RAB11A"} {"geneset":"MORF_RAB1A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAB1A","description":"Neighborhood of RAB1A"} {"geneset":"MORF_RAB3A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAB3A","description":"Neighborhood of RAB3A"} {"geneset":"MORF_RAB5A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAB5A","description":"Neighborhood of RAB5A"} {"geneset":"MORF_RAB6A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAB6A","description":"Neighborhood of RAB6A"} {"geneset":"MORF_RAC1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAC1","description":"Neighborhood of RAC1"} {"geneset":"MORF_RAF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAF1","description":"Neighborhood of RAF1"} {"geneset":"MORF_RAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAGE","description":"Neighborhood of RAGE"} {"geneset":"MORF_RAN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAN","description":"Neighborhood of RAN"} {"geneset":"MORF_RAP1A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAP1A","description":"Neighborhood of RAP1A"} {"geneset":"MORF_RBBP8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RBBP8","description":"Neighborhood of RBBP8"} {"geneset":"MORF_RBM8A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RBM8A","description":"Neighborhood of RBM8A"} {"geneset":"MORF_REV3L","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_REV3L","description":"Neighborhood of REV3L"} {"geneset":"MORF_RUNX1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RUNX1","description":"Neighborhood of RUNX1"} {"geneset":"MORF_SART1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SART1","description":"Neighborhood of SART1"} {"geneset":"MORF_SKP1A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SKP1A","description":"Neighborhood of SKP1A"} {"geneset":"MORF_SNRP70","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SNRP70","description":"Neighborhood of SNRP70"} {"geneset":"MORF_SS18","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SS18","description":"Neighborhood of SS18"} {"geneset":"MORF_SUPT3H","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SUPT3H","description":"Neighborhood of SUPT3H"} {"geneset":"MORF_THPO","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_THPO","description":"Neighborhood of THPO"} {"geneset":"MORF_THRA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_THRA","description":"Neighborhood of THRA"} {"geneset":"MORF_TNFRSF25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TNFRSF25","description":"Neighborhood of TNFRSF25"} {"geneset":"MORF_TNFRSF6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TNFRSF6","description":"Neighborhood of TNFRSF6"} {"geneset":"MORF_TPR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TPR","description":"Neighborhood of TPR"} {"geneset":"MORF_TPT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TPT1","description":"Neighborhood of TPT1"} {"geneset":"MORF_TTN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_TTN","description":"Neighborhood of TTN"} {"geneset":"MORF_UBE2A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_UBE2A","description":"Neighborhood of UBE2A"} {"geneset":"MORF_UBE2I","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_UBE2I","description":"Neighborhood of UBE2I"} {"geneset":"MORF_UBE2N","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_UBE2N","description":"Neighborhood of UBE2N"} {"geneset":"MORF_USP5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_USP5","description":"Neighborhood of USP5"} {"geneset":"MORF_WNT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_WNT1","description":"Neighborhood of WNT1"} {"geneset":"MORF_ZNF10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ZNF10","description":"Neighborhood of ZNF10"} {"geneset":"GCM_ATM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_ATM","description":"Neighborhood of ATM"} {"geneset":"GCM_BNIP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_BNIP1","description":"Neighborhood of BNIP1"} {"geneset":"GCM_BAG5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_BAG5","description":"Neighborhood of BAG5"} {"geneset":"GCM_BCL2L1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_BCL2L1","description":"Neighborhood of BCL2L1"} {"geneset":"GCM_BECN1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_BECN1","description":"Neighborhood of BECN1"} {"geneset":"GCM_ERBB2IP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_ERBB2IP","description":"Neighborhood of ERBB2IP"} {"geneset":"GCM_GSTA4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_GSTA4","description":"Neighborhood of GSTA4"} {"geneset":"GCM_HDAC1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_HDAC1","description":"Neighborhood of HDAC1"} {"geneset":"GCM_PSME1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PSME1","description":"Neighborhood of PSME1"} {"geneset":"GCM_RAD21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_RAD21","description":"Neighborhood of RAD21"} {"geneset":"GCM_SIRT2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_SIRT2","description":"Neighborhood of SIRT2"} {"geneset":"GCM_TINF2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_TINF2","description":"Neighborhood of TINF2"} {"geneset":"GCM_ACTG1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_ACTG1","description":"Neighborhood of ACTG1"} {"geneset":"GCM_AIP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_AIP","description":"Neighborhood of AIP"} {"geneset":"GCM_ANP32B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_ANP32B","description":"Neighborhood of ANP32B"} {"geneset":"GCM_APEX1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_APEX1","description":"Neighborhood of APEX1"} {"geneset":"GCM_AQP4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_AQP4","description":"Neighborhood of AQP4"} {"geneset":"GCM_BMPR2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_BMPR2","description":"Neighborhood of BMPR2"} {"geneset":"GCM_CALM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CALM1","description":"Neighborhood of CALM1"} {"geneset":"GCM_CASP2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CASP2","description":"Neighborhood of CASP2"} {"geneset":"GCM_CBFB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CBFB","description":"Neighborhood of CBFB"} {"geneset":"GCM_CDH5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CDH5","description":"Neighborhood of CDH5"} {"geneset":"GCM_CHUK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CHUK","description":"Neighborhood of CHUK"} {"geneset":"GCM_CRKL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CRKL","description":"Neighborhood of CRKL"} {"geneset":"GCM_CSNK1A1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CSNK1A1","description":"Neighborhood of CSNK1A1"} {"geneset":"GCM_CSNK1D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CSNK1D","description":"Neighborhood of CSNK1D"} {"geneset":"GCM_CSNK2B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CSNK2B","description":"Neighborhood of CSNK2B"} {"geneset":"GCM_DDX11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_DDX11","description":"Neighborhood of DDX11"} {"geneset":"GCM_DDX5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_DDX5","description":"Neighborhood of DDX5"} {"geneset":"GCM_DEAF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_DEAF1","description":"Neighborhood of DEAF1"} {"geneset":"GCM_DENR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_DENR","description":"Neighborhood of DENR"} {"geneset":"GCM_DFFA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_DFFA","description":"Neighborhood of DFFA"} {"geneset":"GCM_DLG1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_DLG1","description":"Neighborhood of DLG1"} {"geneset":"GCM_DPF2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_DPF2","description":"Neighborhood of DPF2"} {"geneset":"GCM_ERCC4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_ERCC4","description":"Neighborhood of ERCC4"} {"geneset":"GCM_FANCC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_FANCC","description":"Neighborhood of FANCC"} {"geneset":"GCM_FANCL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_FANCL","description":"Neighborhood of FANCL"} {"geneset":"GCM_FCGR2B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_FCGR2B","description":"Neighborhood of FCGR2B"} {"geneset":"GCM_GSPT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_GSPT1","description":"Neighborhood of GSPT1"} {"geneset":"GCM_HBP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_HBP1","description":"Neighborhood of HBP1"} {"geneset":"GCM_HMGA2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_HMGA2","description":"Neighborhood of HMGA2"} {"geneset":"GCM_IL6ST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_IL6ST","description":"Neighborhood of IL6ST"} {"geneset":"GCM_ING1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_ING1","description":"Neighborhood of ING1"} {"geneset":"GCM_LTK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_LTK","description":"Neighborhood of LTK"} {"geneset":"GCM_MAP1B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MAP1B","description":"Neighborhood of MAP1B"} {"geneset":"GCM_MAP4K4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MAP4K4","description":"Neighborhood of MAP4K4"} {"geneset":"GCM_MAPK10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MAPK10","description":"Neighborhood of MAPK10"} {"geneset":"GCM_MAX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MAX","description":"Neighborhood of MAX"} {"geneset":"GCM_MLL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MLL","description":"Neighborhood of MLL"} {"geneset":"GCM_MSN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MSN","description":"Neighborhood of MSN"} {"geneset":"GCM_MYCL1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MYCL1","description":"Neighborhood of MYCL1"} {"geneset":"GCM_MYST2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_MYST2","description":"Neighborhood of MYST2"} {"geneset":"GCM_NCAM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_NCAM1","description":"Neighborhood of NCAM1"} {"geneset":"GCM_NF2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_NF2","description":"Neighborhood of NF2"} {"geneset":"GCM_NPM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_NPM1","description":"Neighborhood of NPM1"} {"geneset":"GCM_NUMA1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_NUMA1","description":"Neighborhood of NUMA1"} {"geneset":"GCM_PFN1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PFN1","description":"Neighborhood of PFN1"} {"geneset":"GCM_PPM1D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PPM1D","description":"Neighborhood of PPM1D"} {"geneset":"GCM_PPP1CC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PPP1CC","description":"Neighborhood of PPP1CC"} {"geneset":"GCM_PRKAG1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PRKAG1","description":"Neighborhood of PRKAG1"} {"geneset":"GCM_PRKCG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PRKCG","description":"Neighborhood of PRKCG"} {"geneset":"GCM_PTK2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PTK2","description":"Neighborhood of PTK2"} {"geneset":"GCM_PTPRD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PTPRD","description":"Neighborhood of PTPRD"} {"geneset":"GCM_PTPRU","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PTPRU","description":"Neighborhood of PTPRU"} {"geneset":"GCM_RAB10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_RAB10","description":"Neighborhood of RAB10"} {"geneset":"GCM_RAF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_RAF1","description":"Neighborhood of RAF1"} {"geneset":"GCM_RAN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_RAN","description":"Neighborhood of RAN"} {"geneset":"GCM_RAP2A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_RAP2A","description":"Neighborhood of RAP2A"} {"geneset":"GCM_RBM8A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_RBM8A","description":"Neighborhood of RBM8A"} {"geneset":"GCM_RING1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_RING1","description":"Neighborhood of RING1"} {"geneset":"GCM_SMARCC1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_SMARCC1","description":"Neighborhood of SMARCC1"} {"geneset":"GCM_SMARCD1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_SMARCD1","description":"Neighborhood of SMARCD1"} {"geneset":"GCM_SMO","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_SMO","description":"Neighborhood of SMO"} {"geneset":"GCM_SUFU","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_SUFU","description":"Neighborhood of SUFU"} {"geneset":"GCM_SUPT4H1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_SUPT4H1","description":"Neighborhood of SUPT4H1"} {"geneset":"GCM_TEC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_TEC","description":"Neighborhood of TEC"} {"geneset":"GCM_TPR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_TPR","description":"Neighborhood of TPR"} {"geneset":"GCM_TPT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_TPT1","description":"Neighborhood of TPT1"} {"geneset":"GCM_UBE2N","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_UBE2N","description":"Neighborhood of UBE2N"} {"geneset":"GCM_USP6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_USP6","description":"Neighborhood of USP6"} {"geneset":"GCM_VAV1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_VAV1","description":"Neighborhood of VAV1"} {"geneset":"GCM_ZNF198","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCM_ZNF198","description":"Neighborhood of ZNF198"} {"geneset":"CAR_HPX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAR_HPX","description":"Neighborhood of HPX"} {"geneset":"CAR_IGFBP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAR_IGFBP1","description":"Neighborhood of IGFBP1"} {"geneset":"CAR_MLANA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAR_MLANA","description":"Neighborhood of MLANA"} {"geneset":"CAR_MYST2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAR_MYST2","description":"Neighborhood of MYST2"} {"geneset":"CAR_TNFRSF25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAR_TNFRSF25","description":"Neighborhood of TNFRSF25"} {"geneset":"CAR_WBSCR22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAR_WBSCR22","description":"Neighborhood of WBSCR22"} {"geneset":"GNF2_ATM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ATM","description":"Neighborhood of ATM"} {"geneset":"GNF2_BNIP2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_BNIP2","description":"Neighborhood of BNIP2"} {"geneset":"GNF2_BNIP3L","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_BNIP3L","description":"Neighborhood of BNIP3L"} {"geneset":"GNF2_BUB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_BUB1","description":"Neighborhood of BUB1"} {"geneset":"GNF2_BUB3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_BUB3","description":"Neighborhood of BUB3"} {"geneset":"GNF2_CARD15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CARD15","description":"Neighborhood of CARD15"} {"geneset":"GNF2_CDC20","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CDC20","description":"Neighborhood of CDC20"} {"geneset":"GNF2_CDC2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CDC2","description":"Neighborhood of CDC2"} {"geneset":"GNF2_CENPE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CENPE","description":"Neighborhood of CENPE"} {"geneset":"GNF2_CENPF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CENPF","description":"Neighborhood of CENPF"} {"geneset":"GNF2_CCNA1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CCNA1","description":"Neighborhood of CCNA1"} {"geneset":"GNF2_CCNA2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CCNA2","description":"Neighborhood of CCNA2"} {"geneset":"GNF2_CCNB2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CCNB2","description":"Neighborhood of CCNB2"} {"geneset":"GNF2_ESPL1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ESPL1","description":"Neighborhood of ESPL1"} {"geneset":"GNF2_FEN1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_FEN1","description":"Neighborhood of FEN1"} {"geneset":"GNF2_GSTM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_GSTM1","description":"Neighborhood of GSTM1"} {"geneset":"GNF2_H2AFX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_H2AFX","description":"Neighborhood of H2AFX"} {"geneset":"GNF2_HPX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HPX","description":"Neighborhood of HPX"} {"geneset":"GNF2_HAT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HAT1","description":"Neighborhood of HAT1"} {"geneset":"GNF2_HDAC1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HDAC1","description":"Neighborhood of HDAC1"} {"geneset":"GNF2_TDG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TDG","description":"Neighborhood of TDG"} {"geneset":"GNF2_MLH1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MLH1","description":"Neighborhood of MLH1"} {"geneset":"GNF2_MSH2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MSH2","description":"Neighborhood of MSH2"} {"geneset":"GNF2_MSH6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MSH6","description":"Neighborhood of MSH6"} {"geneset":"GNF2_PRDX2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PRDX2","description":"Neighborhood of PRDX2"} {"geneset":"GNF2_PCNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PCNA","description":"Neighborhood of PCNA"} {"geneset":"GNF2_RAD23A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RAD23A","description":"Neighborhood of RAD23A"} {"geneset":"GNF2_RFC3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RFC3","description":"Neighborhood of RFC3"} {"geneset":"GNF2_RFC4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RFC4","description":"Neighborhood of RFC4"} {"geneset":"GNF2_RPA1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RPA1","description":"Neighborhood of RPA1"} {"geneset":"GNF2_RRM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RRM1","description":"Neighborhood of RRM1"} {"geneset":"GNF2_RRM2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RRM2","description":"Neighborhood of RRM2"} {"geneset":"GNF2_SMC1L1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SMC1L1","description":"Neighborhood of SMC1L1"} {"geneset":"GNF2_SMC2L1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SMC2L1","description":"Neighborhood of SMC2L1"} {"geneset":"GNF2_SMC4L1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SMC4L1","description":"Neighborhood of SMC4L1"} {"geneset":"GNF2_TST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TST","description":"Neighborhood of TST"} {"geneset":"GNF2_XRCC5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_XRCC5","description":"Neighborhood of XRCC5"} {"geneset":"GNF2_AF1Q","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_AF1Q","description":"Neighborhood of AF1Q"} {"geneset":"GNF2_ANK1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ANK1","description":"Neighborhood of ANK1"} {"geneset":"GNF2_ANP32B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ANP32B","description":"Neighborhood of ANP32B"} {"geneset":"GNF2_APEX1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_APEX1","description":"Neighborhood of APEX1"} {"geneset":"GNF2_BUB1B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_BUB1B","description":"Neighborhood of BUB1B"} {"geneset":"GNF2_CASP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CASP1","description":"Neighborhood of CASP1"} {"geneset":"GNF2_CASP4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CASP4","description":"Neighborhood of CASP4"} {"geneset":"GNF2_CASP8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CASP8","description":"Neighborhood of CASP8"} {"geneset":"GNF2_CBFB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CBFB","description":"Neighborhood of CBFB"} {"geneset":"GNF2_CD14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD14","description":"Neighborhood of CD14"} {"geneset":"GNF2_CD1D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD1D","description":"Neighborhood of CD1D"} {"geneset":"GNF2_CD33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD33","description":"Neighborhood of CD33"} {"geneset":"GNF2_CD48","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD48","description":"Neighborhood of CD48"} {"geneset":"GNF2_CD53","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD53","description":"Neighborhood of CD53"} {"geneset":"GNF2_CD7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD7","description":"Neighborhood of CD7"} {"geneset":"GNF2_CD97","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD97","description":"Neighborhood of CD97"} {"geneset":"GNF2_CDC27","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CDC27","description":"Neighborhood of CDC27"} {"geneset":"GNF2_CDH11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CDH11","description":"Neighborhood of CDH11"} {"geneset":"GNF2_CDH3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CDH3","description":"Neighborhood of CDH3"} {"geneset":"GNF2_CDKN1C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CDKN1C","description":"Neighborhood of CDKN1C"} {"geneset":"GNF2_CEBPA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CEBPA","description":"Neighborhood of CEBPA"} {"geneset":"GNF2_CKS1B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CKS1B","description":"Neighborhood of CKS1B"} {"geneset":"GNF2_CKS2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CKS2","description":"Neighborhood of CKS2"} {"geneset":"GNF2_CYP2B6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CYP2B6","description":"Neighborhood of CYP2B6"} {"geneset":"GNF2_DAP3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_DAP3","description":"Neighborhood of DAP3"} {"geneset":"GNF2_DDX5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_DDX5","description":"Neighborhood of DDX5"} {"geneset":"GNF2_DEK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_DEK","description":"Neighborhood of DEK"} {"geneset":"GNF2_DENR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_DENR","description":"Neighborhood of DENR"} {"geneset":"GNF2_DNM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_DNM1","description":"Neighborhood of DNM1"} {"geneset":"GNF2_EGFR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_EGFR","description":"Neighborhood of EGFR"} {"geneset":"GNF2_EIF3S6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_EIF3S6","description":"Neighborhood of EIF3S6"} {"geneset":"GNF2_ELAC2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ELAC2","description":"Neighborhood of ELAC2"} {"geneset":"GNF2_FBL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_FBL","description":"Neighborhood of FBL"} {"geneset":"GNF2_FGR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_FGR","description":"Neighborhood of FGR"} {"geneset":"GNF2_FOS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_FOS","description":"Neighborhood of FOS"} {"geneset":"GNF2_G22P1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_G22P1","description":"Neighborhood of G22P1"} {"geneset":"GNF2_GLTSCR2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_GLTSCR2","description":"Neighborhood of GLTSCR2"} {"geneset":"GNF2_HCK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HCK","description":"Neighborhood of HCK"} {"geneset":"GNF2_HLA_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HLA_C","description":"Neighborhood of HLA-C"} {"geneset":"GNF2_HMMR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HMMR","description":"Neighborhood of HMMR"} {"geneset":"GNF2_HPN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HPN","description":"Neighborhood of HPN"} {"geneset":"GNF2_ICAM3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ICAM3","description":"Neighborhood of ICAM3"} {"geneset":"GNF2_IGF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_IGF1","description":"Neighborhood of IGF1"} {"geneset":"GNF2_IGFBP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_IGFBP1","description":"Neighborhood of IGFBP1"} {"geneset":"GNF2_IL2RB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_IL2RB","description":"Neighborhood of IL2RB"} {"geneset":"GNF2_INPP5D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_INPP5D","description":"Neighborhood of INPP5D"} {"geneset":"GNF2_ITGAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ITGAL","description":"Neighborhood of ITGAL"} {"geneset":"GNF2_ITGB2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ITGB2","description":"Neighborhood of ITGB2"} {"geneset":"GNF2_JAK1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_JAK1","description":"Neighborhood of JAK1"} {"geneset":"GNF2_KISS1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_KISS1","description":"Neighborhood of KISS1"} {"geneset":"GNF2_KPNB1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_KPNB1","description":"Neighborhood of KPNB1"} {"geneset":"GNF2_LCAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_LCAT","description":"Neighborhood of LCAT"} {"geneset":"GNF2_LYN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_LYN","description":"Neighborhood of LYN"} {"geneset":"GNF2_MAP2K3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MAP2K3","description":"Neighborhood of MAP2K3"} {"geneset":"GNF2_MAPT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MAPT","description":"Neighborhood of MAPT"} {"geneset":"GNF2_MATK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MATK","description":"Neighborhood of MATK"} {"geneset":"GNF2_MBD4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MBD4","description":"Neighborhood of MBD4"} {"geneset":"GNF2_MCL1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MCL1","description":"Neighborhood of MCL1"} {"geneset":"GNF2_MCM4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MCM4","description":"Neighborhood of MCM4"} {"geneset":"GNF2_MCM5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MCM5","description":"Neighborhood of MCM5"} {"geneset":"GNF2_MKI67","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MKI67","description":"Neighborhood of MKI67"} {"geneset":"GNF2_MLF1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MLF1","description":"Neighborhood of MLF1"} {"geneset":"GNF2_MMP1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MMP1","description":"Neighborhood of MMP1"} {"geneset":"GNF2_MMP11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MMP11","description":"Neighborhood of MMP11"} {"geneset":"GNF2_MSN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MSN","description":"Neighborhood of MSN"} {"geneset":"GNF2_MYD88","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MYD88","description":"Neighborhood of MYD88"} {"geneset":"GNF2_MYL2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MYL2","description":"Neighborhood of MYL2"} {"geneset":"GNF2_MYL3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MYL3","description":"Neighborhood of MYL3"} {"geneset":"GNF2_NPM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_NPM1","description":"Neighborhood of NPM1"} {"geneset":"GNF2_NS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_NS","description":"Neighborhood of NS"} {"geneset":"GNF2_PA2G4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PA2G4","description":"Neighborhood of PA2G4"} {"geneset":"GNF2_PAK2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PAK2","description":"Neighborhood of PAK2"} {"geneset":"GNF2_PCAF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PCAF","description":"Neighborhood of PCAF"} {"geneset":"GNF2_PECAM1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PECAM1","description":"Neighborhood of PECAM1"} {"geneset":"GNF2_PPP6C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PPP6C","description":"Neighborhood of PPP6C"} {"geneset":"GNF2_PTPN4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PTPN4","description":"Neighborhood of PTPN4"} {"geneset":"GNF2_PTPN6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PTPN6","description":"Neighborhood of PTPN6"} {"geneset":"GNF2_PTPRC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PTPRC","description":"Neighborhood of PTPRC"} {"geneset":"GNF2_PTX3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PTX3","description":"Neighborhood of PTX3"} {"geneset":"GNF2_RAB3A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RAB3A","description":"Neighborhood of RAB3A"} {"geneset":"GNF2_RAB7L1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RAB7L1","description":"Neighborhood of RAB7L1"} {"geneset":"GNF2_RAN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RAN","description":"Neighborhood of RAN"} {"geneset":"GNF2_RAP1B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RAP1B","description":"Neighborhood of RAP1B"} {"geneset":"GNF2_RBBP6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RBBP6","description":"Neighborhood of RBBP6"} {"geneset":"GNF2_RTN1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_RTN1","description":"Neighborhood of RTN1"} {"geneset":"GNF2_S100A4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_S100A4","description":"Neighborhood of S100A4"} {"geneset":"GNF2_SELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SELL","description":"Neighborhood of SELL"} {"geneset":"GNF2_SERPINB5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SERPINB5","description":"Neighborhood of SERPINB5"} {"geneset":"GNF2_SERPINI2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SERPINI2","description":"Neighborhood of SERPINI2"} {"geneset":"GNF2_SNRK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SNRK","description":"Neighborhood of SNRK"} {"geneset":"GNF2_SPI1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SPI1","description":"Neighborhood of SPI1"} {"geneset":"GNF2_SPINK1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SPINK1","description":"Neighborhood of SPINK1"} {"geneset":"GNF2_SPRR1B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SPRR1B","description":"Neighborhood of SPRR1B"} {"geneset":"GNF2_SPTA1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SPTA1","description":"Neighborhood of SPTA1"} {"geneset":"GNF2_SPTB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SPTB","description":"Neighborhood of SPTB"} {"geneset":"GNF2_ST13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ST13","description":"Neighborhood of ST13"} {"geneset":"GNF2_STAT6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_STAT6","description":"Neighborhood of STAT6"} {"geneset":"GNF2_TAL1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TAL1","description":"Neighborhood of TAL1"} {"geneset":"GNF2_TIMP2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TIMP2","description":"Neighborhood of TIMP2"} {"geneset":"GNF2_TM4SF2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TM4SF2","description":"Neighborhood of TM4SF2"} {"geneset":"GNF2_TNFRSF1B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TNFRSF1B","description":"Neighborhood of TNFRSF1B"} {"geneset":"GNF2_TNFSF10","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TNFSF10","description":"Neighborhood of TNFSF10"} {"geneset":"GNF2_TPT1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TPT1","description":"Neighborhood of TPT1"} {"geneset":"GNF2_TTK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TTK","description":"Neighborhood of TTK"} {"geneset":"GNF2_TTN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TTN","description":"Neighborhood of TTN"} {"geneset":"GNF2_TYK2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_TYK2","description":"Neighborhood of TYK2"} {"geneset":"GNF2_UBE2I","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_UBE2I","description":"Neighborhood of UBE2I"} {"geneset":"GNF2_VAV1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_VAV1","description":"Neighborhood of VAV1"} {"geneset":"GNF2_ZAP70","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ZAP70","description":"Neighborhood of ZAP70"} {"geneset":"MODULE_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_1","description":"Ovary genes."} {"geneset":"MODULE_2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_2","description":"DRG (dorsal root ganglia) genes."} {"geneset":"MODULE_3","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_3","description":"Genes in the cancer module 3."} {"geneset":"MODULE_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_4","description":"Genes in the cancer module 4."} {"geneset":"MODULE_5","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_5","description":"Lung genes."} {"geneset":"MODULE_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_6","description":"Trachea genes."} {"geneset":"MODULE_7","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_7","description":"Genes in the cancer module 7."} {"geneset":"MODULE_8","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_8","description":"Genes in the cancer module 8."} {"geneset":"MODULE_9","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_9","description":"Genes in the cancer module 9."} {"geneset":"MODULE_11","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_11","description":"Genes in the cancer module 11."} {"geneset":"MODULE_12","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_12","description":"Spinal cord (neuro-development) genes."} {"geneset":"MODULE_13","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_13","description":"Genes in the cancer module 12."} {"geneset":"MODULE_14","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_14","description":"Genes in the cancer module 13."} {"geneset":"MODULE_15","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_15","description":"Genes in the cancer module 14."} {"geneset":"MODULE_16","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_16","description":"Genes in the cancer module 15."} {"geneset":"MODULE_17","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_17","description":"Genes in the cancer module 17."} {"geneset":"MODULE_18","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_18","description":"Genes in the cancer module 18."} {"geneset":"MODULE_19","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_19","description":"Adrenal gland - metabolic genes."} {"geneset":"MODULE_20","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_20","description":"Genes in the cancer module 20."} {"geneset":"MODULE_21","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_21","description":"Genes in the cancer module 21."} {"geneset":"MODULE_22","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_22","description":"Genes in the cancer module 22."} {"geneset":"MODULE_23","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_23","description":"Liver genes - metabolism and xenobiotics."} {"geneset":"MODULE_24","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_24","description":"Fetal liver genes - metabolism and xenobiotics."} {"geneset":"MODULE_25","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_25","description":"Genes in the cancer module 25."} {"geneset":"MODULE_26","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_26","description":"Genes in the cancer module 26."} {"geneset":"MODULE_27","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_27","description":"Genes in the cancer module 27."} {"geneset":"MODULE_28","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_28","description":"Genes in the cancer module 28."} {"geneset":"MODULE_29","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_29","description":"Genes in the cancer module 29."} {"geneset":"MODULE_32","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_32","description":"Genes in the cancer module 32."} {"geneset":"MODULE_33","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_33","description":"Immune / stress response genes."} {"geneset":"MODULE_35","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_35","description":"Genes in the cancer module 35."} {"geneset":"MODULE_36","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_36","description":"Genes in the cancer module 36."} {"geneset":"MODULE_37","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_37","description":"Genes in the cancer module 37."} {"geneset":"MODULE_38","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_38","description":"Placenta genes."} {"geneset":"MODULE_39","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_39","description":"Genes in the cancer module 39."} {"geneset":"MODULE_40","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_40","description":"Organic acid metabolism."} {"geneset":"MODULE_41","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_41","description":"Genes in the cancer module 41."} {"geneset":"MODULE_42","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_42","description":"Genes in the cancer module 42."} {"geneset":"MODULE_43","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_43","description":"Energy pathways."} {"geneset":"MODULE_44","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_44","description":"Thymus genes."} {"geneset":"MODULE_45","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_45","description":"Whole blood genes."} {"geneset":"MODULE_46","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_46","description":"Genes in the cancer module 46."} {"geneset":"MODULE_47","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_47","description":"ECM and collagens."} {"geneset":"MODULE_48","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_48","description":"Genes in the cancer module 48."} {"geneset":"MODULE_49","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_49","description":"Genes in the cancer module 49."} {"geneset":"MODULE_50","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_50","description":"Genes in the cancer module 50."} {"geneset":"MODULE_51","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_51","description":"Genes in the cancer module 51."} {"geneset":"MODULE_52","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_52","description":"Cell line expressed genes."} {"geneset":"MODULE_53","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_53","description":"Cell line expressed genes."} {"geneset":"MODULE_54","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_54","description":"Cell cycle (expression cluster)."} {"geneset":"MODULE_55","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_55","description":"Genes in the cancer module 55."} {"geneset":"MODULE_56","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_56","description":"Cell cycle (KEGG, GenMapp)."} {"geneset":"MODULE_57","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_57","description":"Genes in the cancer module 57."} {"geneset":"MODULE_58","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_58","description":"Genes in the cancer module 58."} {"geneset":"MODULE_59","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_59","description":"Genes in the cancer module 59."} {"geneset":"MODULE_60","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_60","description":"Heart genes."} {"geneset":"MODULE_61","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_61","description":"Genes in the cancer module 61."} {"geneset":"MODULE_62","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_62","description":"Genes in the cancer module 62."} {"geneset":"MODULE_63","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_63","description":"Porins / transporters."} {"geneset":"MODULE_64","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_64","description":"Membranal receptors."} {"geneset":"MODULE_65","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_65","description":"Genes in the cancer module 65."} {"geneset":"MODULE_66","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_66","description":"Genes in the cancer module 66."} {"geneset":"MODULE_67","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_67","description":"Genes in the cancer module 67."} {"geneset":"MODULE_68","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_68","description":"Genes in the cancer module 68."} {"geneset":"MODULE_69","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_69","description":"Genes in the cancer module 69."} {"geneset":"MODULE_70","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_70","description":"Genes in the cancer module 70."} {"geneset":"MODULE_71","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_71","description":"Genes in the cancer module 71."} {"geneset":"MODULE_72","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_72","description":"Testis genes."} {"geneset":"MODULE_73","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_73","description":"Genes in the cancer module 73."} {"geneset":"MODULE_75","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_75","description":"Immune response."} {"geneset":"MODULE_76","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_76","description":"Inflammatory response."} {"geneset":"MODULE_77","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_77","description":"Genes in the cancer module 77."} {"geneset":"MODULE_78","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_78","description":"AA metabolism."} {"geneset":"MODULE_79","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_79","description":"Genes in the cancer module 79."} {"geneset":"MODULE_80","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_80","description":"Genes in the cancer module 80."} {"geneset":"MODULE_81","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_81","description":"Genes in the cancer module 81."} {"geneset":"MODULE_82","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_82","description":"Genes in the cancer module 82."} {"geneset":"MODULE_83","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_83","description":"Genes in the cancer module 83."} {"geneset":"MODULE_84","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_84","description":"Immune (humoral) and inflammatory response."} {"geneset":"MODULE_85","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_85","description":"Genes in the cancer module 85."} {"geneset":"MODULE_86","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_86","description":"Small monomeric GTPases."} {"geneset":"MODULE_87","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_87","description":"Genes in the cancer module 87."} {"geneset":"MODULE_88","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_88","description":"Heart, liver, kidney and pancreas metabolic and xenobiotic response genes."} {"geneset":"MODULE_89","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_89","description":"Genes in the cancer module 89."} {"geneset":"MODULE_90","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_90","description":"Genes in the cancer module 90."} {"geneset":"MODULE_91","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_91","description":"Proteasome."} {"geneset":"MODULE_92","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_92","description":"Secreted signaling molecules."} {"geneset":"MODULE_93","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_93","description":"Oxidoreductases."} {"geneset":"MODULE_94","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_94","description":"Signaling."} {"geneset":"MODULE_95","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_95","description":"Genes in the cancer module 95."} {"geneset":"MODULE_96","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_96","description":"Genes in the cancer module 96."} {"geneset":"MODULE_97","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_97","description":"Genes in the cancer module 97."} {"geneset":"MODULE_98","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_98","description":"Genes in the cancer module 98."} {"geneset":"MODULE_99","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_99","description":"Genes in the cancer module 99."} {"geneset":"MODULE_100","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_100","description":"Genes in the cancer module 100."} {"geneset":"MODULE_101","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_101","description":"Genes in the cancer module 101."} {"geneset":"MODULE_102","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_102","description":"Nucleotide (purine) biosynthesis."} {"geneset":"MODULE_103","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_103","description":"Genes in the cancer module 103."} {"geneset":"MODULE_104","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_104","description":"Genes in the cancer module 104."} {"geneset":"MODULE_105","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_105","description":"Genes in the cancer module 105."} {"geneset":"MODULE_106","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_106","description":"Cytochrome P450."} {"geneset":"MODULE_107","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_107","description":"Genes in the cancer module 107."} {"geneset":"MODULE_108","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_108","description":"Genes in the cancer module 108."} {"geneset":"MODULE_109","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_109","description":"Serine proteases."} {"geneset":"MODULE_110","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_110","description":"Genes in the cancer module 110."} {"geneset":"MODULE_111","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_111","description":"Genes in the cancer module 111."} {"geneset":"MODULE_112","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_112","description":"Genes in the cancer module 112."} {"geneset":"MODULE_113","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_113","description":"Genes in the cancer module 113."} {"geneset":"MODULE_114","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_114","description":"Protein biosynthesis and ribosomes."} {"geneset":"MODULE_115","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_115","description":"Genes in the cancer module 115."} {"geneset":"MODULE_116","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_116","description":"Genes in the cancer module 116."} {"geneset":"MODULE_117","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_117","description":"Signaling."} {"geneset":"MODULE_118","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_118","description":"cell line expressed genes."} {"geneset":"MODULE_119","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_119","description":"Genes in the cancer module 119."} {"geneset":"MODULE_120","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_120","description":"Genes in the cancer module 120."} {"geneset":"MODULE_121","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_121","description":"Genes in the cancer module 121."} {"geneset":"MODULE_122","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_122","description":"Adhesion molecules."} {"geneset":"MODULE_123","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_123","description":"Genes in the cancer module 123."} {"geneset":"MODULE_124","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_124","description":"Transcription."} {"geneset":"MODULE_125","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_125","description":"Genes in the cancer module 125."} {"geneset":"MODULE_126","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_126","description":"Lymphoma and immune response expression clusters."} {"geneset":"MODULE_127","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_127","description":"Genes in the cancer module 127."} {"geneset":"MODULE_128","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_128","description":"Genes in the cancer module 128."} {"geneset":"MODULE_129","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_129","description":"Signaling."} {"geneset":"MODULE_130","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_130","description":"Complement."} {"geneset":"MODULE_131","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_131","description":"Blood coagulation factors."} {"geneset":"MODULE_132","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_132","description":"Genes in the cancer module 132."} {"geneset":"MODULE_133","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_133","description":"Genes in the cancer module 133."} {"geneset":"MODULE_134","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_134","description":"Genes in the cancer module 134."} {"geneset":"MODULE_135","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_135","description":"Genes in the cancer module 135."} {"geneset":"MODULE_136","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_136","description":"Genes in the cancer module 136."} {"geneset":"MODULE_137","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_137","description":"CNS genes."} {"geneset":"MODULE_138","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_138","description":"Genes in the cancer module 138."} {"geneset":"MODULE_139","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_139","description":"Genes in the cancer module 139."} {"geneset":"MODULE_141","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_141","description":"Genes in the cancer module 141."} {"geneset":"MODULE_143","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_143","description":"Genes in the cancer module 143."} {"geneset":"MODULE_145","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_145","description":"Genes in the cancer module 145."} {"geneset":"MODULE_146","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_146","description":"Genes in the cancer module 146."} {"geneset":"MODULE_147","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_147","description":"GPCR."} {"geneset":"MODULE_148","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_148","description":"Genes in the cancer module 148."} {"geneset":"MODULE_149","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_149","description":"Translation factors."} {"geneset":"MODULE_150","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_150","description":"Ttranslation elongation."} {"geneset":"MODULE_151","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_151","description":"Genes in the cancer module 151."} {"geneset":"MODULE_152","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_152","description":"Oxidative phosphorylation and ATP synthesis."} {"geneset":"MODULE_153","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_153","description":"Genes in the cancer module 153."} {"geneset":"MODULE_154","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_154","description":"Intermediate filaments."} {"geneset":"MODULE_155","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_155","description":"Genes in the cancer module 155."} {"geneset":"MODULE_156","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_156","description":"Genes in the cancer module 156."} {"geneset":"MODULE_157","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_157","description":"Genes in the cancer module 157."} {"geneset":"MODULE_158","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_158","description":"DNA replication."} {"geneset":"MODULE_159","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_159","description":"Translation regulation."} {"geneset":"MODULE_160","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_160","description":"tRNA synthesis."} {"geneset":"MODULE_162","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_162","description":"Genes in the cancer module 162."} {"geneset":"MODULE_163","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_163","description":"Genes in the cancer module 163."} {"geneset":"MODULE_164","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_164","description":"Enzyme inhibitors (esp serine proteases)."} {"geneset":"MODULE_165","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_165","description":"Genes in the cancer module 165."} {"geneset":"MODULE_166","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_166","description":"Genes in the cancer module 166."} {"geneset":"MODULE_168","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_168","description":"Genes in the cancer module 168."} {"geneset":"MODULE_169","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_169","description":"Immune response."} {"geneset":"MODULE_170","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_170","description":"Immune response."} {"geneset":"MODULE_171","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_171","description":"Genes in the cancer module 171."} {"geneset":"MODULE_172","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_172","description":"Genes in the cancer module 172."} {"geneset":"MODULE_173","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_173","description":"Genes in the cancer module 173."} {"geneset":"MODULE_174","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_174","description":"Genes in the cancer module 174."} {"geneset":"MODULE_175","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_175","description":"Genes in the cancer module 175."} {"geneset":"MODULE_176","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_176","description":"Signaling."} {"geneset":"MODULE_177","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_177","description":"Genes in the cancer module 177."} {"geneset":"MODULE_178","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_178","description":"Genes in the cancer module 178."} {"geneset":"MODULE_179","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_179","description":"Blood cells and cancer expression cancer."} {"geneset":"MODULE_180","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_180","description":"Genes in the cancer module 180."} {"geneset":"MODULE_181","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_181","description":"Genes in the cancer module 181."} {"geneset":"MODULE_182","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_182","description":"Genes in the cancer module 182."} {"geneset":"MODULE_183","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_183","description":"RNA splicing."} {"geneset":"MODULE_184","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_184","description":"Genes in the cancer module 184."} {"geneset":"MODULE_186","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_186","description":"Genes in the cancer module 186."} {"geneset":"MODULE_188","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_188","description":"Genes in the cancer module 188."} {"geneset":"MODULE_189","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_189","description":"Genes in the cancer module 189."} {"geneset":"MODULE_190","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_190","description":"IGFBPs."} {"geneset":"MODULE_191","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_191","description":"Genes in the cancer module 191."} {"geneset":"MODULE_192","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_192","description":"Genes in the cancer module 192."} {"geneset":"MODULE_194","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_194","description":"Genes in the cancer module 194."} {"geneset":"MODULE_195","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_195","description":"Breast cancer expression clusters."} {"geneset":"MODULE_196","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_196","description":"Genes in the cancer module 196."} {"geneset":"MODULE_197","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_197","description":"Genes in the cancer module 197."} {"geneset":"MODULE_198","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_198","description":"Genes in the cancer module 198."} {"geneset":"MODULE_199","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_199","description":"Genes in the cancer module 199."} {"geneset":"MODULE_200","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_200","description":"Genes in the cancer module 200."} {"geneset":"MODULE_201","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_201","description":"Genes in the cancer module 201."} {"geneset":"MODULE_202","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_202","description":"Genes in the cancer module 202."} {"geneset":"MODULE_203","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_203","description":"Genes in the cancer module 203."} {"geneset":"MODULE_204","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_204","description":"Genes in the cancer module 204."} {"geneset":"MODULE_205","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_205","description":"Genes in the cancer module 205."} {"geneset":"MODULE_206","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_206","description":"Genes in the cancer module 206."} {"geneset":"MODULE_207","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_207","description":"Genes in the cancer module 207."} {"geneset":"MODULE_208","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_208","description":"Genes in the cancer module 208."} {"geneset":"MODULE_209","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_209","description":"Catabolic peptidases."} {"geneset":"MODULE_210","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_210","description":"Genes in the cancer module 210."} {"geneset":"MODULE_211","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_211","description":"Genes in the cancer module 211."} {"geneset":"MODULE_212","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_212","description":"Catalytic activities / metabolism."} {"geneset":"MODULE_213","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_213","description":"NCI cell lines expression clusters."} {"geneset":"MODULE_214","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_214","description":"Ion channels."} {"geneset":"MODULE_215","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_215","description":"Neurotransmitter (GABA) receptor."} {"geneset":"MODULE_218","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_218","description":"Genes in the cancer module 218."} {"geneset":"MODULE_219","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_219","description":"Genes in the cancer module 219."} {"geneset":"MODULE_220","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_220","description":"Developmental processes."} {"geneset":"MODULE_221","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_221","description":"Fatty acid metabolism."} {"geneset":"MODULE_222","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_222","description":"Genes in the cancer module 222."} {"geneset":"MODULE_223","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_223","description":"Immune (defense) response."} {"geneset":"MODULE_226","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_226","description":"Genes in the cancer module 226."} {"geneset":"MODULE_227","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_227","description":"Genes in the cancer module 227."} {"geneset":"MODULE_229","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_229","description":"Genes in the cancer module 229."} {"geneset":"MODULE_233","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_233","description":"Genes in the cancer module 233."} {"geneset":"MODULE_234","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_234","description":"Bone remodeling."} {"geneset":"MODULE_235","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_235","description":"AA and sulfur metabolism."} {"geneset":"MODULE_236","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_236","description":"Genes in the cancer module 236."} {"geneset":"MODULE_237","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_237","description":"Genes in the cancer module 237."} {"geneset":"MODULE_238","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_238","description":"Genes in the cancer module 238."} {"geneset":"MODULE_239","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_239","description":"Genes in the cancer module 239."} {"geneset":"MODULE_240","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_240","description":"Genes in the cancer module 240."} {"geneset":"MODULE_241","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_241","description":"Genes in the cancer module 241."} {"geneset":"MODULE_242","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_242","description":"Genes in the cancer module 242."} {"geneset":"MODULE_243","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_243","description":"Genes in the cancer module 243."} {"geneset":"MODULE_244","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_244","description":"Response to DNA damage."} {"geneset":"MODULE_245","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_245","description":"Genes in the cancer module 245."} {"geneset":"MODULE_247","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_247","description":"Xenobiotic metabolism."} {"geneset":"MODULE_248","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_248","description":"Genes in the cancer module 248."} {"geneset":"MODULE_249","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_249","description":"Genes in the cancer module 249."} {"geneset":"MODULE_252","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_252","description":"TFs and nuclear."} {"geneset":"MODULE_253","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_253","description":"Intracellular transport (MT cytoskeleton and motors)."} {"geneset":"MODULE_254","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_254","description":"Genes in the cancer module 254."} {"geneset":"MODULE_255","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_255","description":"Genes in the cancer module 255."} {"geneset":"MODULE_256","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_256","description":"Genes in the cancer module 256."} {"geneset":"MODULE_257","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_257","description":"Genes in the cancer module 257."} {"geneset":"MODULE_259","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_259","description":"RTK signaling."} {"geneset":"MODULE_261","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_261","description":"Genes in the cancer module 262."} {"geneset":"MODULE_262","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_262","description":"Cell ion homeostasis / chemokines."} {"geneset":"MODULE_263","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_263","description":"Chemotaxis (chemokines)."} {"geneset":"MODULE_264","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_264","description":"Genes in the cancer module 264."} {"geneset":"MODULE_265","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_265","description":"Caner module 265: IL receptors."} {"geneset":"MODULE_267","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_267","description":"Genes in the cancer module 267."} {"geneset":"MODULE_272","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_272","description":"Genes in the cancer module 272."} {"geneset":"MODULE_273","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_273","description":"Phosphate metabolism."} {"geneset":"MODULE_274","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_274","description":"Vesicular transport / synapse genes."} {"geneset":"MODULE_275","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_275","description":"Genes in the cancer module 275."} {"geneset":"MODULE_277","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_277","description":"Genes in the cancer module 277."} {"geneset":"MODULE_278","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_278","description":"Ubiquitin ligases."} {"geneset":"MODULE_279","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_279","description":"Genes in the cancer module 279."} {"geneset":"MODULE_280","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_280","description":"Metal ion (zinc) binding."} {"geneset":"MODULE_281","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_281","description":"Phosphatase regulators."} {"geneset":"MODULE_284","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_284","description":"Genes in the cancer module 284."} {"geneset":"MODULE_285","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_285","description":"Genes in the cancer module 285."} {"geneset":"MODULE_286","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_286","description":"Genes in the cancer module 286"} {"geneset":"MODULE_287","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_287","description":"Genes in the cancer module 287."} {"geneset":"MODULE_288","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_288","description":"Genes in the cancer module 288."} {"geneset":"MODULE_289","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_289","description":"Genes in the cancer module 289."} {"geneset":"MODULE_291","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_291","description":"B-cell malignancies expression clusters."} {"geneset":"MODULE_292","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_292","description":"Genes in the cancer module 292."} {"geneset":"MODULE_293","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_293","description":"Genes in the cancer module 293."} {"geneset":"MODULE_294","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_294","description":"Genes in the cancer module 294."} {"geneset":"MODULE_295","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_295","description":"Genes in the cancer module 295."} {"geneset":"MODULE_297","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_297","description":"Genes in the cancer module 297."} {"geneset":"MODULE_298","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_298","description":"Keratin."} {"geneset":"MODULE_299","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_299","description":"Genes in the cancer module 299."} {"geneset":"MODULE_300","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_300","description":"Programmed cell death."} {"geneset":"MODULE_301","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_301","description":"Genes in the cancer module 301."} {"geneset":"MODULE_303","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_303","description":"Genes in the cancer module 303."} {"geneset":"MODULE_305","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_305","description":"CoA and fatty acid metabolism."} {"geneset":"MODULE_306","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_306","description":"Glycolysis and TCA cycle."} {"geneset":"MODULE_307","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_307","description":"Oxidative phosphorylation (COX and ATPases)."} {"geneset":"MODULE_308","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_308","description":"Pol II transcription."} {"geneset":"MODULE_310","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_310","description":"ROS metabolism."} {"geneset":"MODULE_311","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_311","description":"Genes in the cancer module 311."} {"geneset":"MODULE_312","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_312","description":"Viral anti-apoptotic evasion mechanisms."} {"geneset":"MODULE_313","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_313","description":"Genes in the cancer module 313."} {"geneset":"MODULE_315","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_315","description":"Spindle and kinetochore."} {"geneset":"MODULE_316","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_316","description":"Ion channels."} {"geneset":"MODULE_317","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_317","description":"Genes in the cancer module 317."} {"geneset":"MODULE_318","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_318","description":"Genes in the cancer module 318."} {"geneset":"MODULE_320","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_320","description":"Cancer module 320: M phase."} {"geneset":"MODULE_321","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_321","description":"Genes in the cancer module 321."} {"geneset":"MODULE_322","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_322","description":"Genes in the cancer module 322."} {"geneset":"MODULE_323","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_323","description":"Genes in the cancer module 323."} {"geneset":"MODULE_324","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_324","description":"Metal / Ca ion binding."} {"geneset":"MODULE_325","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_325","description":"Genes in the cancer module 325."} {"geneset":"MODULE_326","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_326","description":"Genes in the cancer module 326."} {"geneset":"MODULE_327","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_327","description":"Genes in the cancer module 327."} {"geneset":"MODULE_328","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_328","description":"AcetylCholine receptors."} {"geneset":"MODULE_329","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_329","description":"Genes in the cancer module 329."} {"geneset":"MODULE_330","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_330","description":"Genes in the cancer module 330."} {"geneset":"MODULE_331","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_331","description":"Genes in the cancer module 331."} {"geneset":"MODULE_332","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_332","description":"Genes in the cancer module 332."} {"geneset":"MODULE_333","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_333","description":"Genes in the cancer module 333."} {"geneset":"MODULE_334","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_334","description":"Genes in the cancer module 334."} {"geneset":"MODULE_335","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_335","description":"Genes in the cancer module 335."} {"geneset":"MODULE_337","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_337","description":"Nucleotide metabolism."} {"geneset":"MODULE_340","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_340","description":"Genes in the cancer module 340."} {"geneset":"MODULE_341","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_341","description":"Genes in the cancer module 341."} {"geneset":"MODULE_342","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_342","description":"Genes in the cancer module 342."} {"geneset":"MODULE_343","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_343","description":"Nitrogen metabolism."} {"geneset":"MODULE_345","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_345","description":"Immune response and Ag processing and presentation."} {"geneset":"MODULE_346","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_346","description":"Genes in the cancer module 346."} {"geneset":"MODULE_349","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_349","description":"Genes in the cancer module 349."} {"geneset":"MODULE_350","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_350","description":"Genes in the cancer module 350."} {"geneset":"MODULE_352","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_352","description":"Nuclear pore complex."} {"geneset":"MODULE_354","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_354","description":"AA biosynthesis."} {"geneset":"MODULE_355","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_355","description":"Protein folding."} {"geneset":"MODULE_356","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_356","description":"Genes in the cancer module 356."} {"geneset":"MODULE_357","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_357","description":"Intermediate filaments and keratins."} {"geneset":"MODULE_358","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_358","description":"B lymphoma expression clusters."} {"geneset":"MODULE_360","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_360","description":"Genes in the cancer module 360."} {"geneset":"MODULE_361","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_361","description":"B lymphoma expression clusters."} {"geneset":"MODULE_362","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_362","description":"Angiogenesis."} {"geneset":"MODULE_363","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_363","description":"Genes in the cancer module 363."} {"geneset":"MODULE_366","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_366","description":"Breast cancer expression clusters."} {"geneset":"MODULE_367","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_367","description":"Genes in the cancer module 367."} {"geneset":"MODULE_368","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_368","description":"Peptide and AA transporters."} {"geneset":"MODULE_371","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_371","description":"Genes in the cancer module 371."} {"geneset":"MODULE_372","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_372","description":"Genes in the cancer module 372."} {"geneset":"MODULE_373","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_373","description":"Oxidoreductases."} {"geneset":"MODULE_375","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_375","description":"GPCR signaling pathways (immune and neuro)."} {"geneset":"MODULE_377","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_377","description":"Energy pathways and carbohydrate metabolism."} {"geneset":"MODULE_378","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_378","description":"Genes in the cancer module 378."} {"geneset":"MODULE_379","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_379","description":"Genes in the cancer module 379."} {"geneset":"MODULE_381","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_381","description":"Genes in the cancer module 381."} {"geneset":"MODULE_382","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_382","description":"Peptide hormones."} {"geneset":"MODULE_385","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_385","description":"Heparin binding."} {"geneset":"MODULE_387","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_387","description":"Genes in the cancer module 387."} {"geneset":"MODULE_388","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_388","description":"Spliceosome."} {"geneset":"MODULE_389","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_389","description":"Breast cancer expression clusters."} {"geneset":"MODULE_392","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_392","description":"rRNA processing and DNA repair."} {"geneset":"MODULE_395","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_395","description":"Genes in the cancer module 395."} {"geneset":"MODULE_396","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_396","description":"Genes in the cancer module 396."} {"geneset":"MODULE_397","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_397","description":"Genes in the cancer module 397."} {"geneset":"MODULE_399","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_399","description":"Genes in the cancer module 399."} {"geneset":"MODULE_400","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_400","description":"Genes in the cancer module 400."} {"geneset":"MODULE_401","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_401","description":"Genes in the cancer module 401."} {"geneset":"MODULE_402","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_402","description":"Genes in the cancer module 402."} {"geneset":"MODULE_403","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_403","description":"DNA damage response."} {"geneset":"MODULE_404","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_404","description":"Steroid hormone receptors and binding proteins."} {"geneset":"MODULE_407","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_407","description":"Growth suppressors."} {"geneset":"MODULE_408","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_408","description":"Genes in the cancer module 408."} {"geneset":"MODULE_410","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_410","description":"Cell adhesion."} {"geneset":"MODULE_411","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_411","description":"Genes in the cancer module 411."} {"geneset":"MODULE_412","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_412","description":"Genes in the cancer module 412."} {"geneset":"MODULE_414","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_414","description":"Genes in the cancer module 414."} {"geneset":"MODULE_415","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_415","description":"Genes in the cancer module 415."} {"geneset":"MODULE_416","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_416","description":"Genes in the cancer module 416."} {"geneset":"MODULE_417","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_417","description":"Genes in the cancer module 417."} {"geneset":"MODULE_418","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_418","description":"Genes in the cancer module 418."} {"geneset":"MODULE_419","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_419","description":"Genes in the cancer module 419."} {"geneset":"MODULE_421","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_421","description":"Chromatin."} {"geneset":"MODULE_424","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_424","description":"Genes in the cancer module 424."} {"geneset":"MODULE_426","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_426","description":"Genes in the cancer module 426."} {"geneset":"MODULE_427","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_427","description":"Genes in the cancer module 427."} {"geneset":"MODULE_429","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_429","description":"Genes in the cancer module 429."} {"geneset":"MODULE_430","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_430","description":"Genes in the cancer module 430."} {"geneset":"MODULE_431","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_431","description":"Eicosanoid metabolism."} {"geneset":"MODULE_432","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_432","description":"Genes in the cancer module 432."} {"geneset":"MODULE_433","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_433","description":"Cytokines and GFs."} {"geneset":"MODULE_436","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_436","description":"Genes in the cancer module 436."} {"geneset":"MODULE_438","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_438","description":"Intermediate filaments and MT."} {"geneset":"MODULE_439","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_439","description":"Genes in the cancer module 439."} {"geneset":"MODULE_440","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_440","description":"Urea cycle metabolism."} {"geneset":"MODULE_444","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_444","description":"Genes in the cancer module 444."} {"geneset":"MODULE_445","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_445","description":"Genes in the cancer module 445."} {"geneset":"MODULE_447","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_447","description":"Genes in the cancer module 447."} {"geneset":"MODULE_448","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_448","description":"Genes in the cancer module 448."} {"geneset":"MODULE_451","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_451","description":"Genes in the cancer module 451."} {"geneset":"MODULE_453","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_453","description":"Genes in the cancer module 453."} {"geneset":"MODULE_454","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_454","description":"Genes in the cancer module 454."} {"geneset":"MODULE_455","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_455","description":"Genes in the cancer module 455."} {"geneset":"MODULE_456","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_456","description":"B lymphoma expression clusters."} {"geneset":"MODULE_457","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_457","description":"Genes in the cancer module 457."} {"geneset":"MODULE_458","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_458","description":"Genes in the cancer module 458."} {"geneset":"MODULE_459","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_459","description":"Genes in the cancer module 459."} {"geneset":"MODULE_462","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_462","description":"Eicosanoid metabolism (and related carboxylic acid biosynthesis)."} {"geneset":"MODULE_464","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_464","description":"Oxidoreductases."} {"geneset":"MODULE_465","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_465","description":"Genes in the cancer module 465."} {"geneset":"MODULE_470","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_470","description":"Genes in the cancer module 470."} {"geneset":"MODULE_471","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_471","description":"Genes in the cancer module 471."} {"geneset":"MODULE_474","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_474","description":"Genes in the cancer module 474."} {"geneset":"MODULE_478","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_478","description":"Genes in the cancer module 478."} {"geneset":"MODULE_480","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_480","description":"Breast cancer expression clusters."} {"geneset":"MODULE_481","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_481","description":"Genes in the cancer module 481."} {"geneset":"MODULE_484","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_484","description":"Genes in the cancer module 484."} {"geneset":"MODULE_485","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_485","description":"Genes in the cancer module 485."} {"geneset":"MODULE_486","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_486","description":"Genes in the cancer module 486."} {"geneset":"MODULE_488","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_488","description":"Growth inhibitory genes."} {"geneset":"MODULE_489","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_489","description":"Genes in the cancer module 489."} {"geneset":"MODULE_491","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_491","description":"Genes in the cancer module 491."} {"geneset":"MODULE_492","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_492","description":"Genes in the cancer module 492."} {"geneset":"MODULE_493","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_493","description":"Genes in the cancer module 493."} {"geneset":"MODULE_495","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_495","description":"Genes in the cancer module 495."} {"geneset":"MODULE_497","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_497","description":"CNS development."} {"geneset":"MODULE_500","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_500","description":"Genes in the cancer module 500."} {"geneset":"MODULE_501","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_501","description":"Genes in the cancer module 501."} {"geneset":"MODULE_503","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_503","description":"Genes in the cancer module 503."} {"geneset":"MODULE_505","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_505","description":"Steroid hormone and heme metabolism."} {"geneset":"MODULE_509","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_509","description":"Genes in the cancer module 509."} {"geneset":"MODULE_511","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_511","description":"Genes in the cancer module 511."} {"geneset":"MODULE_512","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_512","description":"Muscle genes."} {"geneset":"MODULE_514","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_514","description":"Genes in the cancer module 514."} {"geneset":"MODULE_516","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_516","description":"Genes in the cancer module 516."} {"geneset":"MODULE_519","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_519","description":"Oxidoreductases."} {"geneset":"MODULE_521","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_521","description":"T-cell proliferation genes."} {"geneset":"MODULE_522","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_522","description":"Immune response genes."} {"geneset":"MODULE_524","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_524","description":"Actin cytoskeleton binding."} {"geneset":"MODULE_525","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_525","description":"Genes in the cancer module 525."} {"geneset":"MODULE_528","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_528","description":"Genes in the cancer module 528."} {"geneset":"MODULE_530","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_530","description":"ROS (glutathione, ox stress)."} {"geneset":"MODULE_532","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_532","description":"Blood cells and cancer expression clusters."} {"geneset":"MODULE_533","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_533","description":"Genes in the cancer module 533."} {"geneset":"MODULE_534","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_534","description":"Genes in the cancer module 534."} {"geneset":"MODULE_537","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_537","description":"Anti-apoptosis."} {"geneset":"MODULE_539","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_539","description":"Genes in the cancer module 539."} {"geneset":"MODULE_540","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_540","description":"Iron ion homeostasis."} {"geneset":"MODULE_543","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_543","description":"Annexin, MHCII, and lectins."} {"geneset":"MODULE_544","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_544","description":"Genes in the cancer module 544."} {"geneset":"MODULE_545","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_545","description":"IL-1 signaling."} {"geneset":"MODULE_547","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_547","description":"Genes in the cancer module 547."} {"geneset":"MODULE_552","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_552","description":"Chromatin and nucleosomes."} {"geneset":"MODULE_557","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_557","description":"Genes in the cancer module 557."} {"geneset":"MODULE_560","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_560","description":"Genes in the cancer module 560."} {"geneset":"MODULE_562","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_562","description":"MMPs."} {"geneset":"MODULE_563","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_563","description":"Genes in the cancer module 563."} {"geneset":"MODULE_567","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_567","description":"Genes in the cancer module 567."} {"geneset":"MODULE_568","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_568","description":"Genes in the cancer module 568."} {"geneset":"MODULE_571","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_571","description":"Genes in the cancer module 571."} {"geneset":"MODULE_573","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_573","description":"Cell cycle regulators and carbohydrate transporters."} {"geneset":"MODULE_575","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_575","description":"Complement and cAMP signaling."} {"geneset":"MODULE_576","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MODULE_576","description":"Genes in the cancer module 576."} {"geneset":"GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION","description":"Any process that activates or increases the frequency, rate or extent of viral transcription."} {"geneset":"GO_CARDIAC_CHAMBER_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CHAMBER_DEVELOPMENT","description":"The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart."} {"geneset":"GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY","description":"A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair."} {"geneset":"GO_CIRCADIAN_RHYTHM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CIRCADIAN_RHYTHM","description":"Any biological process in an organism that recurs with a regularity of approximately 24 hours."} {"geneset":"GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING","description":"Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains."} {"geneset":"GO_SPINAL_CORD_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINAL_CORD_DEVELOPMENT","description":"The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues."} {"geneset":"GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands."} {"geneset":"GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus."} {"geneset":"GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly."} {"geneset":"GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus."} {"geneset":"GO_POTASSIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POTASSIUM_ION_TRANSPORT","description":"The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."} {"geneset":"GO_CARDIAC_MUSCLE_ADAPTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_MUSCLE_ADAPTATION","description":"The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION","description":"Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation."} {"geneset":"GO_MOVEMENT_IN_ENVIRONMENT_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MOVEMENT_IN_ENVIRONMENT_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION","description":"The directed movement of an organism or motile cell on, within or near a second organism, where the two organisms are in a symbiotic interaction."} {"geneset":"GO_REGULATION_OF_PROTEIN_TARGETING_TO_MITOCHONDRION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_TARGETING_TO_MITOCHONDRION","description":"Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion."} {"geneset":"GO_APICAL_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APICAL_PROTEIN_LOCALIZATION","description":"Any process in which a protein is transported to, or maintained in, apical regions of the cell."} {"geneset":"GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY","description":"Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates."} {"geneset":"GO_FOREBRAIN_NEURON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOREBRAIN_NEURON_DEVELOPMENT","description":"The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_MATURATION","description":"Any process that activates or increases the frequency, rate or extent of protein maturation."} {"geneset":"GO_NEUROMUSCULAR_JUNCTION_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROMUSCULAR_JUNCTION_DEVELOPMENT","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction."} {"geneset":"GO_MITOTIC_CYTOKINESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_CYTOKINESIS","description":"A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress."} {"geneset":"GO_SMAD_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMAD_PROTEIN_SIGNAL_TRANSDUCTION","description":"The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell."} {"geneset":"GO_CYTOPLASMIC_TRANSLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_TRANSLATION","description":"The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein."} {"geneset":"GO_MEIOTIC_CHROMOSOME_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEIOTIC_CHROMOSOME_SEGREGATION","description":"The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle."} {"geneset":"GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR","description":"Any process that modulates the frequency, rate or extent of double-strand break repair."} {"geneset":"GO_RNA_DEPENDENT_DNA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_DEPENDENT_DNA_BIOSYNTHETIC_PROCESS","description":"A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand."} {"geneset":"GO_REGULATION_OF_B_CELL_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_B_CELL_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell."} {"geneset":"GO_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity."} {"geneset":"GO_DENDRITE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. A dendrite is a freely branching protoplasmic process of a nerve cell."} {"geneset":"GO_REGULATION_OF_RESPIRATORY_BURST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPIRATORY_BURST","description":"Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."} {"geneset":"GO_G_PROTEIN_COUPLED_RECEPTOR_INTERNALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_RECEPTOR_INTERNALIZATION","description":"The process that results in the uptake of a G-protein coupled receptor into an endocytic vesicle."} {"geneset":"GO_MEMORY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMORY","description":"The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)."} {"geneset":"GO_NEURON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_DEVELOPMENT","description":"The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."} {"geneset":"GO_REGULATION_OF_GOLGI_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GOLGI_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of Golgi organization."} {"geneset":"GO_ENDOTHELIAL_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOTHELIAL_CELL_DEVELOPMENT","description":"The progression of an endothelial cell over time, from its formation to the mature structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION","description":"Any process that increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."} {"geneset":"GO_REGULATION_OF_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_ACTIVATION","description":"Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand."} {"geneset":"GO_MULTICELLULAR_ORGANISM_AGING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISM_AGING","description":"An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700)."} {"geneset":"GO_ATP_DEPENDENT_CHROMATIN_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATP_DEPENDENT_CHROMATIN_REMODELING","description":"Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors."} {"geneset":"GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS","description":"The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."} {"geneset":"GO_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ION_TRANSPORT","description":"The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_LIPID_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_MODIFICATION","description":"The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid."} {"geneset":"GO_NEGATIVE_REGULATION_OF_KIDNEY_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_KIDNEY_DEVELOPMENT","description":"Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_REGULATION_OF_HEPATOCYTE_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEPATOCYTE_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of hepatocyte proliferation."} {"geneset":"GO_ACYLGLYCEROL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACYLGLYCEROL_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY","description":"Any process that stops or reduces the activity of a phosphoprotein phosphatase."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly."} {"geneset":"GO_HEMOGLOBIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEMOGLOBIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving hemoglobin, including its uptake and utilization."} {"geneset":"GO_SINGLE_FERTILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_FERTILIZATION","description":"The union of male and female gametes to form a zygote."} {"geneset":"GO_LEUKOCYTE_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_ACTIVATION","description":"A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor."} {"geneset":"GO_CHROMOSOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_ORGANIZATION","description":"A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome."} {"geneset":"GO_REGULATION_OF_MITOCHONDRIAL_DEPOLARIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOCHONDRIAL_DEPOLARIZATION","description":"Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity."} {"geneset":"GO_SYNAPTIC_VESICLE_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_VESICLE_LOCALIZATION","description":"Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location."} {"geneset":"GO_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."} {"geneset":"GO_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."} {"geneset":"GO_ESTABLISHMENT_OF_SPINDLE_ORIENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_SPINDLE_ORIENTATION","description":"Any process that set the alignment of spindle relative to other cellular structures."} {"geneset":"GO_METANEPHRIC_NEPHRON_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METANEPHRIC_NEPHRON_MORPHOGENESIS","description":"The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros."} {"geneset":"GO_GLYCERALDEHYDE_3_PHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCERALDEHYDE_3_PHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis."} {"geneset":"GO_RESPONSE_TO_UV_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_UV_C","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm."} {"geneset":"GO_CARBOHYDRATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."} {"geneset":"GO_DENTATE_GYRUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENTATE_GYRUS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus."} {"geneset":"GO_ESTABLISHMENT_OR_MAINTENANCE_OF_TRANSMEMBRANE_ELECTROCHEMICAL_GRADIENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OR_MAINTENANCE_OF_TRANSMEMBRANE_ELECTROCHEMICAL_GRADIENT","description":"The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore."} {"geneset":"GO_LABYRINTHINE_LAYER_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LABYRINTHINE_LAYER_DEVELOPMENT","description":"The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state."} {"geneset":"GO_N_TERMINAL_PROTEIN_AMINO_ACID_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_N_TERMINAL_PROTEIN_AMINO_ACID_ACETYLATION","description":"The acetylation of the N-terminal amino acid of proteins."} {"geneset":"GO_NEUROLOGICAL_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROLOGICAL_SYSTEM_PROCESS","description":"A organ system process carried out by any of the organs or tissues of neurological system."} {"geneset":"GO_NEURONAL_STEM_CELL_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURONAL_STEM_CELL_DIVISION","description":"The self-renewing division of a neuronal stem cell."} {"geneset":"GO_CERAMIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CERAMIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid."} {"geneset":"GO_EXCRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXCRETION","description":"The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds."} {"geneset":"GO_DIGESTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIGESTION","description":"The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."} {"geneset":"GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC","description":"Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."} {"geneset":"GO_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION","description":"Any process that activates or increases the frequency, rate or extent of mitosis."} {"geneset":"GO_HINDBRAIN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HINDBRAIN_DEVELOPMENT","description":"The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)."} {"geneset":"GO_OLIGOSACCHARIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLIGOSACCHARIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT","description":"Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."} {"geneset":"GO_MODULATION_OF_GROWTH_OF_SYMBIONT_INVOLVED_IN_INTERACTION_WITH_HOST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODULATION_OF_GROWTH_OF_SYMBIONT_INVOLVED_IN_INTERACTION_WITH_HOST","description":"Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism."} {"geneset":"GO_CHROMOSOME_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_SEGREGATION","description":"The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity."} {"geneset":"GO_ETHER_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ETHER_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds."} {"geneset":"GO_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION","description":"The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells."} {"geneset":"GO_CYTOKINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving cytokines, any of a group of proteins or glycoproteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity."} {"geneset":"GO_ANTEROGRADE_AXONAL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTEROGRADE_AXONAL_TRANSPORT","description":"The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."} {"geneset":"GO_STEROID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification."} {"geneset":"GO_ALDITOL_PHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALDITOL_PHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."} {"geneset":"GO_SODIUM_INDEPENDENT_ORGANIC_ANION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_INDEPENDENT_ORGANIC_ANION_TRANSPORT","description":"The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY","description":"Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity."} {"geneset":"GO_REGULATION_OF_INTERFERON_BETA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERFERON_BETA_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interferon-beta production."} {"geneset":"GO_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION","description":"The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase."} {"geneset":"GO_N_GLYCAN_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_N_GLYCAN_PROCESSING","description":"The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking."} {"geneset":"GO_INORGANIC_ION_IMPORT_INTO_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INORGANIC_ION_IMPORT_INTO_CELL","description":"The directed movement of inorganic ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_TO_CYTOSOL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_TO_CYTOSOL_TRANSPORT","description":"The directed movement of substances from endoplasmic reticulum to cytosol."} {"geneset":"GO_NEGATIVE_REGULATION_OF_REPRODUCTIVE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_REPRODUCTIVE_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process."} {"geneset":"GO_G_PROTEIN_COUPLED_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity."} {"geneset":"GO_MEMBRANE_DEPOLARIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_DEPOLARIZATION","description":"The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential."} {"geneset":"GO_OLFACTORY_BULB_INTERNEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLFACTORY_BULB_INTERNEURON_DIFFERENTIATION","description":"The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb."} {"geneset":"GO_POSITIVE_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity."} {"geneset":"GO_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE","description":"The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex."} {"geneset":"GO_REGULATION_OF_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LYASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring."} {"geneset":"GO_RESPONSE_TO_NITROGEN_COMPOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_NITROGEN_COMPOUND","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."} {"geneset":"GO_REGULATION_OF_DNA_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_RECOMBINATION","description":"Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents."} {"geneset":"GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of leukocyte proliferation."} {"geneset":"GO_RESPONSE_TO_ETHANOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ETHANOL","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus."} {"geneset":"GO_SULFUR_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFUR_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."} {"geneset":"GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT1_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT1_PROTEIN","description":"Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein."} {"geneset":"GO_REGULATION_OF_CELL_CYCLE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CYCLE_CHECKPOINT","description":"Any process that modulates the frequency, rate or extent of cell cycle checkpoint."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING","description":"Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_REPLICATION","description":"Any process that activates or increases the frequency, rate or extent of DNA replication."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons."} {"geneset":"GO_POSITIVE_REGULATION_OF_REPRODUCTIVE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_REPRODUCTIVE_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of reproductive process."} {"geneset":"GO_POSITIVE_REGULATION_OF_METANEPHROS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_METANEPHROS_DEVELOPMENT","description":"Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process."} {"geneset":"GO_NUCLEOTIDE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_PHOSPHORYLATION","description":"The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside."} {"geneset":"GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC","description":"Any epigenetic process that activates or increases the rate of gene expression."} {"geneset":"GO_GLUTAMATE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMATE_SECRETION","description":"The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system."} {"geneset":"GO_REGULATION_OF_MRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MRNA_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of mRNA metabolic process."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING","description":"Any process that activates or increases the frequency, rate or extent of protein binding."} {"geneset":"GO_REGULATION_OF_NFAT_PROTEIN_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NFAT_PROTEIN_IMPORT_INTO_NUCLEUS","description":"Any process that modulates the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus."} {"geneset":"GO_REGULATION_OF_VASCULOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VASCULOGENESIS","description":"Any process that modulates the frequency, rate or extent of vasculogenesis."} {"geneset":"GO_LENS_FIBER_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LENS_FIBER_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities."} {"geneset":"GO_SENSORY_PERCEPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_PERCEPTION","description":"The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."} {"geneset":"GO_HEPATICOBILIARY_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEPATICOBILIARY_SYSTEM_DEVELOPMENT","description":"The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins."} {"geneset":"GO_FATTY_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."} {"geneset":"GO_REGULATION_OF_VESICLE_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VESICLE_FUSION","description":"Any process that modulates the frequency, rate or extent of vesicle fusion."} {"geneset":"GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I_BIOGENESIS","description":"The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together."} {"geneset":"GO_REGULATION_OF_LIPID_STORAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPID_STORAGE","description":"Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."} {"geneset":"GO_CARBOHYDRATE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_TRANSPORT","description":"The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y."} {"geneset":"GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS","description":"Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."} {"geneset":"GO_EMBRYONIC_HEMOPOIESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_HEMOPOIESIS","description":"The stages of blood cell formation that take place within the embryo."} {"geneset":"GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING","description":"The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell."} {"geneset":"GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II","description":"The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex."} {"geneset":"GO_RESPONSE_TO_IONIZING_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_IONIZING_RADIATION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays."} {"geneset":"GO_PROTEIN_EXPORT_FROM_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_EXPORT_FROM_NUCLEUS","description":"The directed movement of a protein from the nucleus into the cytoplasm."} {"geneset":"GO_EPITHELIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION","description":"Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system."} {"geneset":"GO_SECONDARY_METABOLITE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECONDARY_METABOLITE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon."} {"geneset":"GO_CELL_MIGRATION_INVOLVED_IN_HEART_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MIGRATION_INVOLVED_IN_HEART_DEVELOPMENT","description":"The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CYTOSKELETON","description":"A process in which a protein is transported to, or maintained in, a location within the cytoskeleton."} {"geneset":"GO_NUCLEAR_ENVELOPE_REASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_ENVELOPE_REASSEMBLY","description":"The reformation of the nuclear envelope following its breakdown in the context of a normal process."} {"geneset":"GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR","description":"A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered."} {"geneset":"GO_REGULATION_OF_AUTOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_AUTOPHAGY","description":"Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."} {"geneset":"GO_PHOSPHOLIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester."} {"geneset":"GO_AMMONIUM_ION_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMMONIUM_ION_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving the ammonium ion."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_4_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_4_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-4 production."} {"geneset":"GO_NCRNA_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NCRNA_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs)."} {"geneset":"GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of adipocyte differentiation."} {"geneset":"GO_GLUTAMINE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMINE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."} {"geneset":"GO_REGULATION_OF_PROTEIN_ACTIVATION_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_ACTIVATION_CASCADE","description":"Any process that modulates the frequency, rate or extent of protein activation cascade."} {"geneset":"GO_REGULATION_OF_TELOMERASE_RNA_LOCALIZATION_TO_CAJAL_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TELOMERASE_RNA_LOCALIZATION_TO_CAJAL_BODY","description":"Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body."} {"geneset":"GO_REGULATION_OF_RNA_STABILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RNA_STABILITY","description":"Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs."} {"geneset":"GO_BUNDLE_OF_HIS_CELL_TO_PURKINJE_MYOCYTE_COMMUNICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BUNDLE_OF_HIS_CELL_TO_PURKINJE_MYOCYTE_COMMUNICATION","description":"The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."} {"geneset":"GO_REGULATION_OF_CELL_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_MATURATION","description":"Any process that modulates the frequency, rate or extent of cell maturation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT","description":"Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."} {"geneset":"GO_MAMMARY_GLAND_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAMMARY_GLAND_MORPHOGENESIS","description":"The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."} {"geneset":"GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY","description":"The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups."} {"geneset":"GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_INFLAMMATORY_RESPONSE","description":"Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response."} {"geneset":"GO_URETER_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_URETER_DEVELOPMENT","description":"The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut."} {"geneset":"GO_BODY_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BODY_MORPHOGENESIS","description":"The process in which the anatomical structures of the soma are generated and organized."} {"geneset":"GO_SOMATIC_STEM_CELL_POPULATION_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMATIC_STEM_CELL_POPULATION_MAINTENANCE","description":"Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line."} {"geneset":"GO_CYTOPLASMIC_MICROTUBULE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_MICROTUBULE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","description":"Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."} {"geneset":"GO_PROTEIN_ACTIVATION_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_ACTIVATION_CASCADE","description":"A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events."} {"geneset":"GO_POSITIVE_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY","description":"Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."} {"geneset":"GO_REGULATION_OF_COLLATERAL_SPROUTING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_COLLATERAL_SPROUTING","description":"Any process that modulates the frequency, rate or extent of collateral sprouting."} {"geneset":"GO_ESTABLISHMENT_OR_MAINTENANCE_OF_MONOPOLAR_CELL_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OR_MAINTENANCE_OF_MONOPOLAR_CELL_POLARITY","description":"Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis."} {"geneset":"GO_NEURON_RECOGNITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_RECOGNITION","description":"The process in which a neuronal cell in a multicellular organism interprets its surroundings."} {"geneset":"GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar."} {"geneset":"GO_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION","description":"Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule."} {"geneset":"GO_RESPONSE_TO_AMMONIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_AMMONIUM_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_5_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_5_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-5 production."} {"geneset":"GO_REGULATION_OF_GLUCOSE_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLUCOSE_IMPORT","description":"Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."} {"geneset":"GO_PINOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PINOCYTOSIS","description":"An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane."} {"geneset":"GO_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process."} {"geneset":"GO_PHOSPHATIDYLETHANOLAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLETHANOLAMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes."} {"geneset":"GO_PHOSPHATIDYLCHOLINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLCHOLINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes."} {"geneset":"GO_LUNG_EPITHELIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LUNG_EPITHELIUM_DEVELOPMENT","description":"The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung."} {"geneset":"GO_METENCEPHALON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METENCEPHALON_DEVELOPMENT","description":"The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure."} {"geneset":"GO_G_PROTEIN_COUPLED_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity."} {"geneset":"GO_ACTIN_FILAMENT_BUNDLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT_BUNDLE_ORGANIZATION","description":"A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle."} {"geneset":"GO_CELLULAR_RESPONSE_TO_VIRUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_VIRUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus."} {"geneset":"GO_CYTOPLASMIC_MRNA_PROCESSING_BODY_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_MRNA_PROCESSING_BODY_ASSEMBLY","description":"The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."} {"geneset":"GO_RESPIRATORY_GASEOUS_EXCHANGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPIRATORY_GASEOUS_EXCHANGE","description":"The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL","description":"Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal."} {"geneset":"GO_AMINO_ACID_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_ACID_ACTIVATION","description":"The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule."} {"geneset":"GO_DENDRITIC_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITIC_CELL_DIFFERENTIATION","description":"The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation."} {"geneset":"GO_NATURAL_KILLER_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NATURAL_KILLER_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell."} {"geneset":"GO_BONE_TRABECULA_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_TRABECULA_MORPHOGENESIS","description":"The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod."} {"geneset":"GO_REGULATION_OF_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS","description":"Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."} {"geneset":"GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation."} {"geneset":"GO_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of skeletal muscle tissue development."} {"geneset":"GO_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_TISSUE_DEVELOPMENT","description":"The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION","description":"Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues."} {"geneset":"GO_ACID_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACID_SECRETION","description":"The controlled release of acid by a cell or a tissue."} {"geneset":"GO_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate, or extent of an adaptive immune response."} {"geneset":"GO_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of osteoclast differentiation."} {"geneset":"GO_REGULATION_OF_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_BINDING","description":"Any process that modulates the frequency, rate or extent of protein binding."} {"geneset":"GO_CARDIAC_SEPTUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_SEPTUM_DEVELOPMENT","description":"The progression of a cardiac septum over time, from its initial formation to the mature structure."} {"geneset":"GO_REGULATION_OF_ICOSANOID_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ICOSANOID_SECRETION","description":"Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell."} {"geneset":"GO_L_ALPHA_AMINO_ACID_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_L_ALPHA_AMINO_ACID_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of L-alpha-amino acid across a membrane."} {"geneset":"GO_REGULATION_OF_HISTONE_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HISTONE_METHYLATION","description":"Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones."} {"geneset":"GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_FISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_FISSION","description":"Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."} {"geneset":"GO_ANTIMICROBIAL_HUMORAL_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIMICROBIAL_HUMORAL_RESPONSE","description":"An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus."} {"geneset":"GO_EPIDERMIS_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPIDERMIS_MORPHOGENESIS","description":"The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species."} {"geneset":"GO_INTERMEDIATE_FILAMENT_BASED_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERMEDIATE_FILAMENT_BASED_PROCESS","description":"Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins."} {"geneset":"GO_COGNITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COGNITION","description":"The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory."} {"geneset":"GO_RESPONSE_TO_ZINC_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ZINC_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus."} {"geneset":"GO_PURINE_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_DISRUPTION_OF_CELLS_OF_OTHER_ORGANISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DISRUPTION_OF_CELLS_OF_OTHER_ORGANISM","description":"A process in which an organism has a negative effect on the functioning of the second organism's cells."} {"geneset":"GO_AXIS_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXIS_SPECIFICATION","description":"The establishment, maintenance and elaboration of a pattern along a line or around a point."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."} {"geneset":"GO_CELL_PART_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PART_MORPHOGENESIS","description":"The process in which the anatomical structures of a cell part are generated and organized."} {"geneset":"GO_PIGMENT_GRANULE_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIGMENT_GRANULE_LOCALIZATION","description":"Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell."} {"geneset":"GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_RESPONSE_TO_ORGANOPHOSPHORUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ORGANOPHOSPHORUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors."} {"geneset":"GO_AXO_DENDRITIC_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXO_DENDRITIC_TRANSPORT","description":"The directed movement of organelles or molecules along microtubules in neuron projections."} {"geneset":"GO_SINGLE_ORGANISM_MEMBRANE_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_ORGANISM_MEMBRANE_FUSION","description":"The membrane organization process that joins two lipid bilayers to form a single membrane, involving only one organism."} {"geneset":"GO_REGULATION_OF_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process."} {"geneset":"GO_SKELETAL_MUSCLE_TISSUE_REGENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKELETAL_MUSCLE_TISSUE_REGENERATION","description":"The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage."} {"geneset":"GO_POLYSACCHARIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYSACCHARIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."} {"geneset":"GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN","description":"Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."} {"geneset":"GO_ORGAN_REGENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGAN_REGENERATION","description":"The regrowth of a lost or destroyed organ."} {"geneset":"GO_GLAND_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLAND_MORPHOGENESIS","description":"The process in which the anatomical structures of a gland are generated and organized."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response."} {"geneset":"GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_CIRCULATORY_RENIN_ANGIOTENSIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_CIRCULATORY_RENIN_ANGIOTENSIN","description":"The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen."} {"geneset":"GO_RIBOSOME_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOME_BIOGENESIS","description":"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis."} {"geneset":"GO_B_CELL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_B_CELL_HOMEOSTASIS","description":"The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."} {"geneset":"GO_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE","description":"A series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB."} {"geneset":"GO_SINGLE_ORGANISM_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_ORGANISM_BEHAVIOR","description":"The specific behavior of a single organism in response to external or internal stimuli."} {"geneset":"GO_POSITIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS","description":"Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis."} {"geneset":"GO_POSITIVE_REGULATION_OF_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ENDOCYTOSIS","description":"Any process that activates or increases the frequency, rate or extent of endocytosis."} {"geneset":"GO_MRNA_SPLICE_SITE_SELECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_SPLICE_SITE_SELECTION","description":"Selection of a splice site by components of the assembling spliceosome."} {"geneset":"GO_REGULATION_OF_TRANSLATION_IN_RESPONSE_TO_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSLATION_IN_RESPONSE_TO_STRESS","description":"Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION","description":"Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form."} {"geneset":"GO_PHENOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHENOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."} {"geneset":"GO_POSITIVE_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation."} {"geneset":"GO_DENDRITIC_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITIC_CELL_MIGRATION","description":"The movement of a dendritic cell within or between different tissues and organs of the body."} {"geneset":"GO_SENSORY_PERCEPTION_OF_TEMPERATURE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_PERCEPTION_OF_TEMPERATURE_STIMULUS","description":"The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."} {"geneset":"GO_LYSOSOMAL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSOSOMAL_TRANSPORT","description":"The directed movement of substances into, out of or within a lysosome."} {"geneset":"GO_CELLULAR_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process."} {"geneset":"GO_POSITIVE_REGULATION_OF_MACROPHAGE_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MACROPHAGE_ACTIVATION","description":"Any process that stimulates, induces or increases the rate of macrophage activation."} {"geneset":"GO_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING","description":"Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response."} {"geneset":"GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION","description":"Any process that modulates the frequency, rate or extent of alpha-beta T cell activation."} {"geneset":"GO_MUSCLE_ORGAN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_ORGAN_DEVELOPMENT","description":"The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work."} {"geneset":"GO_POSITIVE_REGULATION_OF_HEMOPOIESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HEMOPOIESIS","description":"Any process that activates or increases the frequency, rate or extent of hemopoiesis."} {"geneset":"GO_OUTFLOW_TRACT_SEPTUM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OUTFLOW_TRACT_SEPTUM_MORPHOGENESIS","description":"The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract."} {"geneset":"GO_REGULATION_OF_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation."} {"geneset":"GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring."} {"geneset":"GO_CELLULAR_RESPONSE_TO_EPIDERMAL_GROWTH_FACTOR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_EPIDERMAL_GROWTH_FACTOR_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus."} {"geneset":"GO_LEUKOCYTE_DEGRANULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_DEGRANULATION","description":"The regulated exocytosis of secretory granules by a leukocyte."} {"geneset":"GO_MYELOID_CELL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_CELL_HOMEOSTASIS","description":"The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."} {"geneset":"GO_REGULATION_OF_BLOOD_PRESSURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BLOOD_PRESSURE","description":"Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."} {"geneset":"GO_REGULATION_OF_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE","description":"Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized."} {"geneset":"GO_RESPONSE_TO_ELECTRICAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ELECTRICAL_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERASE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase."} {"geneset":"GO_REGULATION_OF_T_CELL_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_CHEMOTAXIS","description":"Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus."} {"geneset":"GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY_INVOLVED_IN_NEURAL_TUBE_CLOSURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY_INVOLVED_IN_NEURAL_TUBE_CLOSURE","description":"Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube."} {"geneset":"GO_REGULATION_OF_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOKINE_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of production of a cytokine."} {"geneset":"GO_REGULATION_OF_ERBB_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ERBB_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of ERBB signaling pathway."} {"geneset":"GO_REGULATION_OF_CHOLESTEROL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHOLESTEROL_HOMEOSTASIS","description":"Any process that modulates the frequency, rate or extent of cholesterol homeostasis."} {"geneset":"GO_VENTRICULAR_SEPTUM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRICULAR_SEPTUM_MORPHOGENESIS","description":"The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another."} {"geneset":"GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS","description":"Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis."} {"geneset":"GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION","description":"Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation."} {"geneset":"GO_TOLERANCE_INDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOLERANCE_INDUCTION","description":"A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it."} {"geneset":"GO_CHEMICAL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMICAL_HOMEOSTASIS","description":"Any biological process involved in the maintenance of an internal steady state of a chemical."} {"geneset":"GO_SYNAPSE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPSE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."} {"geneset":"GO_METANEPHROS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METANEPHROS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS","description":"Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSPORTER_ACTIVITY","description":"Any process that stops or reduces the activity of a transporter."} {"geneset":"GO_ENDOSOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOSOME_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes."} {"geneset":"GO_REGULATION_OF_WOUND_HEALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_WOUND_HEALING","description":"Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury."} {"geneset":"GO_REGULATION_OF_MAPK_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MAPK_CASCADE","description":"Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade."} {"geneset":"GO_DEVELOPMENTAL_PROGRAMMED_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENTAL_PROGRAMMED_CELL_DEATH","description":"The activation of endogenous cellular processes that result in the death of a cell as part of its development."} {"geneset":"GO_POSITIVE_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that activates, maintains or increases the rate of skeletal muscle tissue development."} {"geneset":"GO_MYELOID_LEUKOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_LEUKOCYTE_MIGRATION","description":"The movement of a myeloid leukocyte within or between different tissues and organs of the body."} {"geneset":"GO_COLLAGEN_FIBRIL_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COLLAGEN_FIBRIL_ORGANIZATION","description":"Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEURON_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEURON_DEATH","description":"Any process that activates or increases the frequency, rate or extent of neuron death."} {"geneset":"GO_RESPONSE_TO_ESTRADIOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ESTRADIOL","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen."} {"geneset":"GO_CORONARY_VASCULATURE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORONARY_VASCULATURE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure."} {"geneset":"GO_CARTILAGE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARTILAGE_DEVELOPMENT","description":"The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."} {"geneset":"GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION","description":"Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."} {"geneset":"GO_NEURON_PROJECTION_EXTENSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_EXTENSION","description":"Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of cardiac muscle tissue development."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides."} {"geneset":"GO_PYRIMIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_RESPONSE_TO_MUSCLE_STRETCH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MUSCLE_STRETCH","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length."} {"geneset":"GO_NEGATIVE_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation."} {"geneset":"GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING","description":"Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade."} {"geneset":"GO_RESPONSE_TO_COLD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_COLD","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SODIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SODIUM_ION_TRANSPORT","description":"Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_1","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus."} {"geneset":"GO_CIRCULATORY_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CIRCULATORY_SYSTEM_PROCESS","description":"A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism."} {"geneset":"GO_REGULATION_OF_VASODILATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VASODILATION","description":"Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels."} {"geneset":"GO_REGULATION_OF_TRIGLYCERIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRIGLYCERIDE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GLYCOPROTEIN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GLYCOPROTEIN_BIOSYNTHETIC_PROCESS","description":"Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."} {"geneset":"GO_RESPONSE_TO_COCAINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_COCAINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant."} {"geneset":"GO_CELL_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CHEMOTAXIS","description":"The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR","description":"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator."} {"geneset":"GO_RIBONUCLEOTIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOTIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_POSITIVE_REGULATION_OF_MITOTIC_SISTER_CHROMATID_SEPARATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MITOTIC_SISTER_CHROMATID_SEPARATION","description":"Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation."} {"geneset":"GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION","description":"The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production."} {"geneset":"GO_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of cation channel activity."} {"geneset":"GO_REGULATION_OF_PROSTAGLANDIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROSTAGLANDIN_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell."} {"geneset":"GO_REGULATION_OF_PODOSOME_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PODOSOME_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of podosome assembly."} {"geneset":"GO_REGULATION_OF_CELLULAR_SENESCENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_SENESCENCE","description":"Any process that modulates the frequency, rate or extent of cellular senescence."} {"geneset":"GO_CARDIAC_LEFT_VENTRICLE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_LEFT_VENTRICLE_MORPHOGENESIS","description":"The process in which the left cardiac ventricle is generated and organized."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation."} {"geneset":"GO_RESPONSE_TO_AMINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_AMINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups."} {"geneset":"GO_REGULATION_OF_ORGANIC_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ORGANIC_ACID_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION","description":"Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands."} {"geneset":"GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity."} {"geneset":"GO_PROTEIN_HOMOTETRAMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HOMOTETRAMERIZATION","description":"The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits."} {"geneset":"GO_IMMUNE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNE_SYSTEM_PROCESS","description":"Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats."} {"geneset":"GO_HEART_TRABECULA_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_TRABECULA_MORPHOGENESIS","description":"The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."} {"geneset":"GO_RESPIRATORY_CHAIN_COMPLEX_IV_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPIRATORY_CHAIN_COMPLEX_IV_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms."} {"geneset":"GO_VESICLE_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_LOCALIZATION","description":"Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location."} {"geneset":"GO_NITRIC_OXIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NITRIC_OXIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."} {"geneset":"GO_POSITIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_FATE_COMMITMENT","description":"Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."} {"geneset":"GO_FOREBRAIN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOREBRAIN_MORPHOGENESIS","description":"The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)."} {"geneset":"GO_TELOMERE_CAPPING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERE_CAPPING","description":"A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins."} {"geneset":"GO_PROSTATE_GLAND_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROSTATE_GLAND_MORPHOGENESIS","description":"The process in which the anatomical structures of a prostate gland are generated and organized."} {"geneset":"GO_NEGATIVE_REGULATION_OF_AXON_EXTENSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_AXON_EXTENSION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth."} {"geneset":"GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."} {"geneset":"GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE","description":"Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade."} {"geneset":"GO_MYELOID_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."} {"geneset":"GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY_INVOLVED_IN_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY_INVOLVED_IN_APOPTOTIC_PROCESS","description":"Any regulation of mitochondrial membrane permeability that is involved in apoptotic process."} {"geneset":"GO_INTRACELLULAR_PROTEIN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_PROTEIN_TRANSPORT","description":"The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell."} {"geneset":"GO_REGULATION_OF_HISTONE_DEACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HISTONE_DEACETYLATION","description":"Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones."} {"geneset":"GO_REGULATION_OF_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHATASE_ACTIVITY","description":"Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."} {"geneset":"GO_NEUROTRANSMITTER_UPTAKE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTRANSMITTER_UPTAKE","description":"The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."} {"geneset":"GO_MICROTUBULE_ANCHORING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_ANCHORING","description":"Any process in which a microtubule is maintained in a specific location in a cell."} {"geneset":"GO_CELL_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DIVISION","description":"The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells."} {"geneset":"GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS","description":"Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."} {"geneset":"GO_INTERMEDIATE_FILAMENT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERMEDIATE_FILAMENT_ORGANIZATION","description":"Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_10_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_10_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-10 production."} {"geneset":"GO_SODIUM_ION_EXPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_ION_EXPORT","description":"The directed movement of sodium ions out of a cell or organelle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_DIVISION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of cell division."} {"geneset":"GO_CELLULAR_RESPONSE_TO_UV","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_UV","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."} {"geneset":"GO_REGULATION_OF_NUCLEAR_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEAR_DIVISION","description":"Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."} {"geneset":"GO_RESPONSE_TO_ACID_CHEMICAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ACID_CHEMICAL","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."} {"geneset":"GO_RESPONSE_TO_PROSTAGLANDIN_E","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PROSTAGLANDIN_E","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES","description":"Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species."} {"geneset":"GO_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","description":"Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."} {"geneset":"GO_RESPONSE_TO_STEROID_HORMONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_STEROID_HORMONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_RNA_SPLICING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RNA_SPLICING","description":"Any process that activates or increases the frequency, rate or extent of RNA splicing."} {"geneset":"GO_RESPONSE_TO_IMMOBILIZATION_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_IMMOBILIZATION_STRESS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile."} {"geneset":"GO_RESPONSE_TO_INTERLEUKIN_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INTERLEUKIN_4","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation."} {"geneset":"GO_CARDIAC_CHAMBER_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CHAMBER_MORPHOGENESIS","description":"The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart."} {"geneset":"GO_REGULATION_OF_CARTILAGE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARTILAGE_DEVELOPMENT","description":"Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-8 production."} {"geneset":"GO_SEROTONIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEROTONIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."} {"geneset":"GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS","description":"Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism."} {"geneset":"GO_RESPONSE_TO_PEPTIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PEPTIDE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus."} {"geneset":"GO_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process."} {"geneset":"GO_DNA_DEPENDENT_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DEPENDENT_DNA_REPLICATION","description":"A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands."} {"geneset":"GO_REGULATION_OF_SKELETAL_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SKELETAL_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process."} {"geneset":"GO_STEROL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROL_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of sterol within an organism or cell."} {"geneset":"GO_EMBRYONIC_AXIS_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_AXIS_SPECIFICATION","description":"The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo."} {"geneset":"GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of leukocyte apoptotic process."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production."} {"geneset":"GO_CELLULAR_RESPONSE_TO_LIPID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_LIPID","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus."} {"geneset":"GO_SECRETION_BY_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECRETION_BY_CELL","description":"The controlled release of a substance by a cell."} {"geneset":"GO_LIPOPROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOPROTEIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."} {"geneset":"GO_DISRUPTION_OF_CELLS_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DISRUPTION_OF_CELLS_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION","description":"A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction."} {"geneset":"GO_IRON_COORDINATION_ENTITY_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IRON_COORDINATION_ENTITY_TRANSPORT","description":"The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_PHOSPHATIDYLCHOLINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLCHOLINE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."} {"geneset":"GO_KERATAN_SULFATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KERATAN_SULFATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."} {"geneset":"GO_REGULATION_OF_COAGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_COAGULATION","description":"Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass."} {"geneset":"GO_MEMBRANE_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_BIOGENESIS","description":"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane."} {"geneset":"GO_REGULATION_OF_EPIDERMIS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPIDERMIS_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of epidermis development."} {"geneset":"GO_FORMATION_OF_PRIMARY_GERM_LAYER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FORMATION_OF_PRIMARY_GERM_LAYER","description":"The formation of the ectoderm, mesoderm and endoderm during gastrulation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation."} {"geneset":"GO_ENERGY_RESERVE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENERGY_RESERVE_METABOLIC_PROCESS","description":"The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen."} {"geneset":"GO_GLYCOLIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOLIPID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)."} {"geneset":"GO_REGULATION_OF_ACTIN_NUCLEATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIN_NUCLEATION","description":"Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament."} {"geneset":"GO_REGULATION_OF_DENDRITIC_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DENDRITIC_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of dendritic cell differentiation."} {"geneset":"GO_EPITHELIAL_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."} {"geneset":"GO_AMIDE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMIDE_TRANSPORT","description":"The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_KINETOCHORE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_KINETOCHORE","description":"Any process in which a protein is transported to, or maintained at, the kinetochore."} {"geneset":"GO_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation."} {"geneset":"GO_PHOTOPERIODISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTOPERIODISM","description":"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species."} {"geneset":"GO_ALPHA_AMINO_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALPHA_AMINO_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of an alpha-amino acid."} {"geneset":"GO_MESENCHYMAL_TO_EPITHELIAL_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESENCHYMAL_TO_EPITHELIAL_TRANSITION","description":"A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell."} {"geneset":"GO_ESTABLISHMENT_OF_ENDOTHELIAL_INTESTINAL_BARRIER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_ENDOTHELIAL_INTESTINAL_BARRIER","description":"The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition."} {"geneset":"GO_SALIVARY_GLAND_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SALIVARY_GLAND_DEVELOPMENT","description":"The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity."} {"geneset":"GO_CELL_CYCLE_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CYCLE_DNA_REPLICATION","description":"The DNA-dependent DNA replication that takes place as part of the cell cycle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."} {"geneset":"GO_CHROMOSOME_CONDENSATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_CONDENSATION","description":"The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS","description":"Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."} {"geneset":"GO_REGULATION_OF_MONOOXYGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MONOOXYGENASE_ACTIVITY","description":"Any process that modulates the activity of a monooxygenase."} {"geneset":"GO_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS","description":"The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."} {"geneset":"GO_ESTABLISHMENT_OF_EPITHELIAL_CELL_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_EPITHELIAL_CELL_POLARITY","description":"The specification and formation of anisotropic intracellular organization of an epithelial cell."} {"geneset":"GO_TOLL_LIKE_RECEPTOR_9_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOLL_LIKE_RECEPTOR_9_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of binding to toll-like receptor 9."} {"geneset":"GO_EMBRYONIC_DIGIT_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_DIGIT_MORPHOGENESIS","description":"The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe."} {"geneset":"GO_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY","description":"Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."} {"geneset":"GO_NITROGEN_CYCLE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NITROGEN_CYCLE_METABOLIC_PROCESS","description":"A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization."} {"geneset":"GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation."} {"geneset":"GO_NECROPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NECROPTOTIC_PROCESS","description":"A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GLIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GLIOGENESIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia."} {"geneset":"GO_DENDRITIC_CELL_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITIC_CELL_CHEMOTAXIS","description":"The movement of a dendritic cell in response to an external stimulus."} {"geneset":"GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN","description":"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen."} {"geneset":"GO_REGULATION_OF_NEURONAL_SYNAPTIC_PLASTICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEURONAL_SYNAPTIC_PLASTICITY","description":"A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."} {"geneset":"GO_REGULATION_OF_PHOSPHOLIPASE_C_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHOLIPASE_C_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of phospholipase C activity."} {"geneset":"GO_REGULATION_OF_DEVELOPMENTAL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEVELOPMENTAL_GROWTH","description":"Any process that modulates the frequency, rate or extent of developmental growth."} {"geneset":"GO_MEMBRANE_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_DISASSEMBLY","description":"The controlled breakdown of any cell membrane in the context of a normal process such as autophagy."} {"geneset":"GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC","description":"Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."} {"geneset":"GO_ACTIVATION_OF_PHOSPHOLIPASE_C_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_PHOSPHOLIPASE_C_ACTIVITY","description":"The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BONE_RESORPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BONE_RESORPTION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption."} {"geneset":"GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus."} {"geneset":"GO_NADP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NADP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH."} {"geneset":"GO_POSITIVE_REGULATION_OF_MRNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MRNA_PROCESSING","description":"Any process that activates or increases the frequency, rate or extent of mRNA processing."} {"geneset":"GO_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS","description":"The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."} {"geneset":"GO_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION","description":"The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception."} {"geneset":"GO_REGULATION_OF_CELL_CELL_ADHESION_MEDIATED_BY_CADHERIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CELL_ADHESION_MEDIATED_BY_CADHERIN","description":"Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin."} {"geneset":"GO_METANEPHRIC_EPITHELIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METANEPHRIC_EPITHELIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."} {"geneset":"GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation."} {"geneset":"GO_FATTY_ACID_BETA_OXIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_BETA_OXIDATION","description":"A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."} {"geneset":"GO_ACTIN_FILAMENT_BASED_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT_BASED_PROCESS","description":"Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins."} {"geneset":"GO_RESPONSE_TO_FLUID_SHEAR_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_FLUID_SHEAR_STRESS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MUSCLE_CONTRACTION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction."} {"geneset":"GO_TRANSITION_METAL_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSITION_METAL_ION_TRANSPORT","description":"The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver."} {"geneset":"GO_POSITIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of muscle cell differentiation."} {"geneset":"GO_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of an adaptive immune response."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_COMMUNICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_COMMUNICATION","description":"Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."} {"geneset":"GO_POSITIVE_REGULATION_OF_LIPID_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LIPID_KINASE_ACTIVITY","description":"Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid."} {"geneset":"GO_RESPONSE_TO_CORTICOSTEROID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_CORTICOSTEROID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids."} {"geneset":"GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DEGRANULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DEGRANULATION","description":"Any process that activates or increases the frequency, rate or extent of leukocyte degranulation."} {"geneset":"GO_SODIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."} {"geneset":"GO_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","description":"The process in which a ubiquitin group, or multiple groups, are covalently attached to the target protein, thereby initiating the degradation of that protein."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels."} {"geneset":"GO_CELL_PROJECTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PROJECTION_ASSEMBLY","description":"Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon."} {"geneset":"GO_REGULATION_OF_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION","description":"Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane."} {"geneset":"GO_GLUCOCORTICOID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOCORTICOID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."} {"geneset":"GO_PROTEIN_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_MATURATION","description":"Any process leading to the attainment of the full functional capacity of a protein."} {"geneset":"GO_SKELETAL_MUSCLE_ADAPTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKELETAL_MUSCLE_ADAPTATION","description":"Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals."} {"geneset":"GO_PROTEIN_N_LINKED_GLYCOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_N_LINKED_GLYCOSYLATION","description":"A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan."} {"geneset":"GO_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome."} {"geneset":"GO_HINDLIMB_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HINDLIMB_MORPHOGENESIS","description":"The process in which the anatomical structures of the hindlimb are generated and organized."} {"geneset":"GO_ESTABLISHMENT_OR_MAINTENANCE_OF_EPITHELIAL_CELL_APICAL_BASAL_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OR_MAINTENANCE_OF_EPITHELIAL_CELL_APICAL_BASAL_POLARITY","description":"Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell."} {"geneset":"GO_LOOP_OF_HENLE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOOP_OF_HENLE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule."} {"geneset":"GO_VESICLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle."} {"geneset":"GO_KERATINOCYTE_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KERATINOCYTE_PROLIFERATION","description":"The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin."} {"geneset":"GO_MACROPHAGE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROPHAGE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."} {"geneset":"GO_INDOLALKYLAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INDOLALKYLAMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group."} {"geneset":"GO_POSITIVE_REGULATION_OF_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BINDING","description":"Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."} {"geneset":"GO_SMOOTH_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMOOTH_MUSCLE_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary."} {"geneset":"GO_MALE_GENITALIA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MALE_GENITALIA_DEVELOPMENT","description":"The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure."} {"geneset":"GO_REGULATION_OF_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HYDROLASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."} {"geneset":"GO_ENDOCARDIAL_CUSHION_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCARDIAL_CUSHION_DEVELOPMENT","description":"The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway."} {"geneset":"GO_RESPONSE_TO_DIETARY_EXCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_DIETARY_EXCESS","description":"The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure."} {"geneset":"GO_REGULATION_OF_MEIOTIC_NUCLEAR_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEIOTIC_NUCLEAR_DIVISION","description":"Any process that modulates the frequency, rate or extent of meiosis, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes."} {"geneset":"GO_BRANCH_ELONGATION_OF_AN_EPITHELIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRANCH_ELONGATION_OF_AN_EPITHELIUM","description":"The growth process in which a branch increases in length from its base to its tip."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides."} {"geneset":"GO_POSITIVE_REGULATION_OF_VACUOLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VACUOLE_ORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION","description":"Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."} {"geneset":"GO_GLUTAMINE_FAMILY_AMINO_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMINE_FAMILY_AMINO_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."} {"geneset":"GO_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT","description":"The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure."} {"geneset":"GO_NEURON_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_MATURATION","description":"A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state."} {"geneset":"GO_THYMIC_T_CELL_SELECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THYMIC_T_CELL_SELECTION","description":"The process of T cell selection that occurs in the thymus."} {"geneset":"GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism."} {"geneset":"GO_COENZYME_A_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COENZYME_A_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CILIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CILIUM","description":"A process in which a protein is transported to, or maintained in, a location within a cilium."} {"geneset":"GO_RNA_STABILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_STABILIZATION","description":"Prevention of degradation of RNA molecules."} {"geneset":"GO_ACTIN_MYOSIN_FILAMENT_SLIDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_MYOSIN_FILAMENT_SLIDING","description":"The sliding movement of actin thin filaments and myosin thick filaments past each other."} {"geneset":"GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."} {"geneset":"GO_REGULATION_OF_PROTEIN_HOMODIMERIZATION_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_HOMODIMERIZATION_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."} {"geneset":"GO_REGULATION_OF_HETEROTYPIC_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HETEROTYPIC_CELL_CELL_ADHESION","description":"Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion."} {"geneset":"GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process."} {"geneset":"GO_ALPHA_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALPHA_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving an alpha-amino acid."} {"geneset":"GO_MITOCHONDRIAL_DNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_DNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving mitochondrial DNA."} {"geneset":"GO_CGMP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CGMP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate."} {"geneset":"GO_ADULT_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADULT_BEHAVIOR","description":"Behavior in a fully developed and mature organism."} {"geneset":"GO_RETINAL_GANGLION_CELL_AXON_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINAL_GANGLION_CELL_AXON_GUIDANCE","description":"The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues."} {"geneset":"GO_POSITIVE_REGULATION_OF_MEMBRANE_INVAGINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MEMBRANE_INVAGINATION","description":"Any process that activates or increases the frequency, rate or extent of membrane invagination."} {"geneset":"GO_SPINDLE_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINDLE_LOCALIZATION","description":"Any process in which is the spindle is transported to, and/or maintained in, a specific location."} {"geneset":"GO_HYDROGEN_PEROXIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROGEN_PEROXIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2)."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response."} {"geneset":"GO_REGULATION_OF_PROTEIN_SUMOYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_SUMOYLATION","description":"Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein."} {"geneset":"GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen."} {"geneset":"GO_CELLULAR_RESPONSE_TO_LIGHT_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_LIGHT_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light."} {"geneset":"GO_POSITIVE_REGULATION_BY_HOST_OF_VIRAL_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_BY_HOST_OF_VIRAL_TRANSCRIPTION","description":"Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response."} {"geneset":"GO_SPHINGOLIPID_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPHINGOLIPID_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals mediated by a sphingolipid."} {"geneset":"GO_SYNAPTIC_VESICLE_CYTOSKELETAL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_VESICLE_CYTOSKELETAL_TRANSPORT","description":"The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors."} {"geneset":"GO_LUNG_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LUNG_CELL_DIFFERENTIATION","description":"The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate."} {"geneset":"GO_PLATELET_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_ACTIVATION","description":"A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug."} {"geneset":"GO_CYTOSKELETON_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSKELETON_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures."} {"geneset":"GO_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process."} {"geneset":"GO_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR","description":"The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway."} {"geneset":"GO_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL","description":"The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."} {"geneset":"GO_MATURATION_OF_SSU_RRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATURATION_OF_SSU_RRNA","description":"Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule."} {"geneset":"GO_BETA_AMYLOID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_AMYLOID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving beta-amyloid, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP)."} {"geneset":"GO_RESPONSE_TO_WOUNDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_WOUNDING","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism."} {"geneset":"GO_NON_CANONICAL_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NON_CANONICAL_WNT_SIGNALING_PATHWAY","description":"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin."} {"geneset":"GO_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_BLOOD_VOLUME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_BLOOD_VOLUME","description":"A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity."} {"geneset":"GO_POSITIVE_REGULATION_OF_CREB_TRANSCRIPTION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CREB_TRANSCRIPTION_FACTOR_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_GROWTH","description":"Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth."} {"geneset":"GO_MODIFIED_AMINO_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODIFIED_AMINO_ACID_TRANSPORT","description":"The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_CGMP_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CGMP_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate."} {"geneset":"GO_PROTEIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SECRETION","description":"The controlled release of proteins from a cell."} {"geneset":"GO_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME","description":"The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition."} {"geneset":"GO_ASSOCIATIVE_LEARNING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASSOCIATIVE_LEARNING","description":"Learning by associating a stimulus (the cause) with a particular outcome (the effect)."} {"geneset":"GO_SNORNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SNORNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS","description":"Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus."} {"geneset":"GO_COFACTOR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COFACTOR_TRANSPORT","description":"The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein."} {"geneset":"GO_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of adipocyte differentiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers."} {"geneset":"GO_EXOGENOUS_DRUG_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXOGENOUS_DRUG_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process."} {"geneset":"GO_REGULATION_OF_PROTEIN_DEACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_DEACETYLATION","description":"Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic"} {"geneset":"GO_OTIC_VESICLE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OTIC_VESICLE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_INITIATION","description":"Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation."} {"geneset":"GO_NEURON_PROJECTION_EXTENSION_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_EXTENSION_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE","description":"Any neuron projection extension that is involved in neuron projection guidance."} {"geneset":"GO_PHOSPHOLIPID_DEPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_DEPHOSPHORYLATION","description":"The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_REPAIR","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair."} {"geneset":"GO_METAL_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METAL_ION_TRANSPORT","description":"The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_INSULIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INSULIN_SECRETION","description":"The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin."} {"geneset":"GO_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION","description":"Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells."} {"geneset":"GO_PREASSEMBLY_OF_GPI_ANCHOR_IN_ER_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PREASSEMBLY_OF_GPI_ANCHOR_IN_ER_MEMBRANE","description":"The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane."} {"geneset":"GO_NECROTIC_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NECROTIC_CELL_DEATH","description":"A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues."} {"geneset":"GO_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells."} {"geneset":"GO_REGULATION_BY_VIRUS_OF_VIRAL_PROTEIN_LEVELS_IN_HOST_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_BY_VIRUS_OF_VIRAL_PROTEIN_LEVELS_IN_HOST_CELL","description":"Any virus-mediated process that modulates the levels of viral proteins in a cell."} {"geneset":"GO_CHROMOSOME_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_LOCALIZATION","description":"Any process in which a chromosome is transported to, or maintained in, a specific location."} {"geneset":"GO_REGULATION_OF_RESPIRATORY_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPIRATORY_SYSTEM_PROCESS","description":"Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system."} {"geneset":"GO_POSITIVE_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of neuron differentiation."} {"geneset":"GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS","description":"The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase."} {"geneset":"GO_ACTIVATION_OF_GTPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_GTPASE_ACTIVITY","description":"Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP."} {"geneset":"GO_INOSITOL_PHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_PHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."} {"geneset":"GO_T_CELL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_HOMEOSTASIS","description":"The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."} {"geneset":"GO_REGULATION_OF_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RECEPTOR_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity."} {"geneset":"GO_HISTONE_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_METHYLATION","description":"The modification of histones by addition of methyl groups."} {"geneset":"GO_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY","description":"Any process that activates or increases the activity of a transporter."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS","description":"Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus."} {"geneset":"GO_ALPHA_BETA_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALPHA_BETA_T_CELL_DIFFERENTIATION","description":"The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex."} {"geneset":"GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME","description":"The directed movement of a protein to a specific location on a chromosome."} {"geneset":"GO_PEPTIDE_CROSS_LINKING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_CROSS_LINKING","description":"The formation of a covalent cross-link between or within protein chains."} {"geneset":"GO_PEPTIDYL_SERINE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_SERINE_MODIFICATION","description":"The modification of peptidyl-serine."} {"geneset":"GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus."} {"geneset":"GO_ROUNDABOUT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ROUNDABOUT_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION","description":"The directed movement of a protein to a specific location."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage stimulus."} {"geneset":"GO_GLUTAMATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid."} {"geneset":"GO_SPHINGOMYELIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPHINGOMYELIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine."} {"geneset":"GO_TRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ATPASE_ACTIVITY","description":"Any process that stops or reduces the rate of ATP hydrolysis by an ATPase."} {"geneset":"GO_POSITIVE_REGULATION_OF_LOCOMOTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LOCOMOTION","description":"Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism."} {"geneset":"GO_REGULATION_OF_DENDRITE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DENDRITE_MORPHOGENESIS","description":"Any process that modulates the frequency, rate or extent of dendrite morphogenesis."} {"geneset":"GO_CELLULAR_RESPONSE_TO_LITHIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_LITHIUM_ION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus."} {"geneset":"GO_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."} {"geneset":"GO_CELLULAR_RESPONSE_TO_PROSTAGLANDIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_PROSTAGLANDIN_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus."} {"geneset":"GO_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process."} {"geneset":"GO_NEGATIVE_REGULATION_OF_VIRAL_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_VIRAL_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant."} {"geneset":"GO_ERYTHROCYTE_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERYTHROCYTE_HOMEOSTASIS","description":"Any process of regulating the production and elimination of erythrocytes within an organism."} {"geneset":"GO_RESPONSE_TO_HEAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_HEAT","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."} {"geneset":"GO_NOTCH_RECEPTOR_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NOTCH_RECEPTOR_PROCESSING","description":"The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor."} {"geneset":"GO_CELLULAR_RESPONSE_TO_CADMIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_CADMIUM_ION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus."} {"geneset":"GO_SUCKLING_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUCKLING_BEHAVIOR","description":"Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast."} {"geneset":"GO_POSITIVE_REGULATION_OF_KIDNEY_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_KIDNEY_DEVELOPMENT","description":"Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_REGULATION_OF_MITOTIC_SPINDLE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOTIC_SPINDLE_CHECKPOINT","description":"Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint."} {"geneset":"GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING","description":"The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription."} {"geneset":"GO_REGULATION_OF_NON_CANONICAL_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NON_CANONICAL_WNT_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway."} {"geneset":"GO_REGULATION_OF_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_KINASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."} {"geneset":"GO_CHROMOSOME_LOCALIZATION_TO_NUCLEAR_ENVELOPE_INVOLVED_IN_HOMOLOGOUS_CHROMOSOME_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_LOCALIZATION_TO_NUCLEAR_ENVELOPE_INVOLVED_IN_HOMOLOGOUS_CHROMOSOME_SEGREGATION","description":"The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination."} {"geneset":"GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MIGRATION","description":"Any process that activates or increases the frequency, rate or extent of lymphocyte migration."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_EXTRAVASATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_EXTRAVASATION","description":"Any process that activates or increases the frequency, rate, or extent of cellular extravasation."} {"geneset":"GO_MYELOID_LEUKOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_LEUKOCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage."} {"geneset":"GO_PEROXISOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEROXISOME_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."} {"geneset":"GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION","description":"The process in which a DNA strand is synthesized from template DNA during replication by the action of polymerases, which add nucleotides to the 3' end of the nascent DNA strand."} {"geneset":"GO_CELLULAR_MODIFIED_AMINO_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_MODIFIED_AMINO_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents."} {"geneset":"GO_SINGLE_ORGANISM_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_ORGANISM_CELL_ADHESION","description":"The attachment, via cell adhesion molecules, of a cell to either another cell of the same organism, or to an underlying substrate of the same organism such as the extracellular matrix."} {"geneset":"GO_POLYOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter."} {"geneset":"GO_APICAL_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APICAL_JUNCTION_ASSEMBLY","description":"The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents."} {"geneset":"GO_PYRIMIDINE_RIBONUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_RIBONUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar."} {"geneset":"GO_LYMPHOCYTE_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_HOMEOSTASIS","description":"The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus."} {"geneset":"GO_SERTOLI_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SERTOLI_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RNA_SPLICING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RNA_SPLICING","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing."} {"geneset":"GO_CELL_CYCLE_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CYCLE_PHASE_TRANSITION","description":"The cell cycle process by which a cell commits to entering the next cell cycle phase."} {"geneset":"GO_TISSUE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TISSUE_MORPHOGENESIS","description":"The process in which the anatomical structures of a tissue are generated and organized."} {"geneset":"GO_ENDOSOME_TO_LYSOSOME_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOSOME_TO_LYSOSOME_TRANSPORT","description":"The directed movement of substances from endosomes to lysosomes."} {"geneset":"GO_MRNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_PROCESSING","description":"Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide."} {"geneset":"GO_RESPONSE_TO_ANGIOTENSIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ANGIOTENSIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen."} {"geneset":"GO_DENDRITIC_SPINE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITIC_SPINE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."} {"geneset":"GO_REGULATION_OF_PROTEIN_OLIGOMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_OLIGOMERIZATION","description":"Any process that modulates the frequency, rate or extent of protein oligomerization."} {"geneset":"GO_HEME_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEME_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring."} {"geneset":"GO_SERINE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SERINE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."} {"geneset":"GO_CEREBELLAR_PURKINJE_CELL_LAYER_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBELLAR_PURKINJE_CELL_LAYER_FORMATION","description":"The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."} {"geneset":"GO_CELLULAR_RESPONSE_TO_CARBOHYDRATE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_CARBOHYDRATE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus."} {"geneset":"GO_INOSITOL_PHOSPHATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_PHOSPHATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."} {"geneset":"GO_C21_STEROID_HORMONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_C21_STEROID_HORMONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY","description":"Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse."} {"geneset":"GO_TRANSMISSION_OF_NERVE_IMPULSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMISSION_OF_NERVE_IMPULSE","description":"The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission."} {"geneset":"GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT","description":"Any process that activates or increases the frequency, rate or extent of vasculature development."} {"geneset":"GO_POSITIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation."} {"geneset":"GO_MEMBRANE_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_FUSION","description":"The membrane organization process that joins two lipid bilayers to form a single membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_TOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TOR_SIGNALING","description":"Any process that activates or increases the frequency, rate or extent of TOR signaling."} {"geneset":"GO_POSITIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of glia cell differentiation."} {"geneset":"GO_MALE_SEX_DETERMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MALE_SEX_DETERMINATION","description":"The specification of male sex of an individual organism."} {"geneset":"GO_TYPE_B_PANCREATIC_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TYPE_B_PANCREATIC_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."} {"geneset":"GO_REGULATION_OF_SUPEROXIDE_ANION_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SUPEROXIDE_ANION_GENERATION","description":"Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell."} {"geneset":"GO_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE","description":"Any process that activates or increases the rate or extent of progression through the mitotic cell cycle."} {"geneset":"GO_LYMPHOCYTE_COSTIMULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_COSTIMULATION","description":"The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation."} {"geneset":"GO_REGULATION_OF_SERINE_TYPE_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SERINE_TYPE_PEPTIDASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of serine-type peptidase activity."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids."} {"geneset":"GO_COFACTOR_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COFACTOR_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate."} {"geneset":"GO_BARBED_END_ACTIN_FILAMENT_CAPPING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BARBED_END_ACTIN_FILAMENT_CAPPING","description":"The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits."} {"geneset":"GO_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS","description":"The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway."} {"geneset":"GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of a type 2 immune response."} {"geneset":"GO_3_UTR_MEDIATED_MRNA_STABILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_3_UTR_MEDIATED_MRNA_STABILIZATION","description":"An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA."} {"geneset":"GO_DRUG_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DRUG_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease."} {"geneset":"GO_POSITIVE_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION","description":"Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction."} {"geneset":"GO_PRIMITIVE_STREAK_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRIMITIVE_STREAK_FORMATION","description":"The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis."} {"geneset":"GO_RESPONSE_TO_PHENYLPROPANOID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PHENYLPROPANOID","description":"Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin."} {"geneset":"GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION","description":"Any process that modulates the frequency, rate or extent of epithelial cell migration."} {"geneset":"GO_POSITIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway."} {"geneset":"GO_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DEATH","description":"Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)."} {"geneset":"GO_CELLULAR_IRON_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_IRON_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell."} {"geneset":"GO_CONTRACTILE_ACTIN_FILAMENT_BUNDLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONTRACTILE_ACTIN_FILAMENT_BUNDLE_ASSEMBLY","description":"Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle."} {"geneset":"GO_MACROMOLECULE_DEACYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMOLECULE_DEACYLATION","description":"The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule."} {"geneset":"GO_TRANSLATIONAL_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATIONAL_INITIATION","description":"The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA."} {"geneset":"GO_ACTIVATION_OF_NF_KAPPAB_INDUCING_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_NF_KAPPAB_INDUCING_KINASE_ACTIVITY","description":"The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues."} {"geneset":"GO_SYNAPTIC_TRANSMISSION_CHOLINERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_TRANSMISSION_CHOLINERGIC","description":"The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse using the neurotransmitter acetylcholine."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response."} {"geneset":"GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION","description":"Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell."} {"geneset":"GO_PLASMA_MEMBRANE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLASMA_MEMBRANE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane."} {"geneset":"GO_REGULATION_OF_NEUROTRANSMITTER_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUROTRANSMITTER_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."} {"geneset":"GO_ACTIVATION_OF_ADENYLATE_CYCLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_ADENYLATE_CYCLASE_ACTIVITY","description":"Any process that initiates the activity of the inactive enzyme adenylate cyclase."} {"geneset":"GO_WHITE_FAT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WHITE_FAT_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole."} {"geneset":"GO_OOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OOGENESIS","description":"The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster."} {"geneset":"GO_REGULATION_OF_SHORT_TERM_NEURONAL_SYNAPTIC_PLASTICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SHORT_TERM_NEURONAL_SYNAPTIC_PLASTICITY","description":"A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity."} {"geneset":"GO_ALDEHYDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALDEHYDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O."} {"geneset":"GO_RESPONSE_TO_TYPE_I_INTERFERON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_TYPE_I_INTERFERON","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."} {"geneset":"GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex."} {"geneset":"GO_HYALURONAN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYALURONAN_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine."} {"geneset":"GO_NEUROTRANSMITTER_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTRANSMITTER_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."} {"geneset":"GO_PENTOSE_PHOSPHATE_SHUNT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PENTOSE_PHOSPHATE_SHUNT","description":"The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses."} {"geneset":"GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_ATP_GENERATION_FROM_ADP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATP_GENERATION_FROM_ADP","description":"The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LOCOMOTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LOCOMOTION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism."} {"geneset":"GO_IMP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving IMP, inosine monophosphate."} {"geneset":"GO_NCRNA_3_END_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NCRNA_3_END_PROCESSING","description":"Any process involved in forming the mature 3' end of a non-coding RNA molecule."} {"geneset":"GO_LYMPH_NODE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPH_NODE_DEVELOPMENT","description":"The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes."} {"geneset":"GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE","description":"A process that modulates the size of a cellular component."} {"geneset":"GO_MITOCHONDRIAL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_TRANSPORT","description":"Transport of substances into, out of or within a mitochondrion."} {"geneset":"GO_SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."} {"geneset":"GO_T_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_PROLIFERATION","description":"The expansion of a T cell population by cell division. Follows T cell activation."} {"geneset":"GO_REGULATION_OF_RESPIRATORY_GASEOUS_EXCHANGE_BY_NEUROLOGICAL_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPIRATORY_GASEOUS_EXCHANGE_BY_NEUROLOGICAL_SYSTEM_PROCESS","description":"A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates."} {"geneset":"GO_PROTEIN_TARGETING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TARGETING","description":"The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif."} {"geneset":"GO_POSITIVE_REGULATION_OF_CHOLESTEROL_EFFLUX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CHOLESTEROL_EFFLUX","description":"Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."} {"geneset":"GO_SINGLE_ORGANISM_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_ORGANISM_BIOSYNTHETIC_PROCESS","description":"A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - involving a single organism."} {"geneset":"GO_POSITIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION","description":"Any process that activates or increases the frequency, rate or extent of viral genome replication."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response."} {"geneset":"GO_REGULATION_OF_ALPHA_AMINO_3_HYDROXY_5_METHYL_4_ISOXAZOLE_PROPIONATE_SELECTIVE_GLUTAMATE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ALPHA_AMINO_3_HYDROXY_5_METHYL_4_ISOXAZOLE_PROPIONATE_SELECTIVE_GLUTAMATE_RECEPTOR_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity."} {"geneset":"GO_REGULATION_OF_ENDOTHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOTHELIAL_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of endothelial cell differentiation."} {"geneset":"GO_REGULATION_OF_NOREPINEPHRINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NOREPINEPHRINE_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine."} {"geneset":"GO_GLIAL_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLIAL_CELL_DEVELOPMENT","description":"The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."} {"geneset":"GO_MITOCHONDRIAL_TRANSLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_TRANSLATION","description":"The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code."} {"geneset":"GO_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity."} {"geneset":"GO_STRIATED_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRIATED_MUSCLE_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle."} {"geneset":"GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE","description":"The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."} {"geneset":"GO_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION","description":"Any process that modulates the frequency, rate or extent of smooth muscle contraction."} {"geneset":"GO_POLYOL_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYOL_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."} {"geneset":"GO_SECOND_MESSENGER_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECOND_MESSENGER_MEDIATED_SIGNALING","description":"Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell."} {"geneset":"GO_CELL_CELL_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_SIGNALING","description":"Any process that mediates the transfer of information from one cell to another."} {"geneset":"GO_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation."} {"geneset":"GO_POSITIVE_REGULATION_OF_COAGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_COAGULATION","description":"Any process that activates or increases the frequency, rate or extent of coagulation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY","description":"Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity."} {"geneset":"GO_LUNG_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LUNG_MORPHOGENESIS","description":"The process in which the anatomical structures of the lung are generated and organized."} {"geneset":"GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ."} {"geneset":"GO_OXIDATIVE_DEMETHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDATIVE_DEMETHYLATION","description":"The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate."} {"geneset":"GO_REGULATION_OF_MACROPHAGE_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MACROPHAGE_ACTIVATION","description":"Any process that modulates the frequency or rate of macrophage activation."} {"geneset":"GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_POSITIVE_REGULATION_OF_MAPK_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MAPK_CASCADE","description":"Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade."} {"geneset":"GO_MULTICELLULAR_ORGANISMAL_MACROMOLECULE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISMAL_MACROMOLECULE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level."} {"geneset":"GO_CARBOHYDRATE_DERIVATIVE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_DERIVATIVE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative."} {"geneset":"GO_L_AMINO_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_L_AMINO_ACID_TRANSPORT","description":"The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ACTION_POTENTIAL","description":"Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."} {"geneset":"GO_REGULATION_OF_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MUSCLE_CONTRACTION","description":"Any process that modulates the frequency, rate or extent of muscle contraction."} {"geneset":"GO_REGULATION_OF_CHOLESTEROL_EFFLUX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHOLESTEROL_EFFLUX","description":"Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."} {"geneset":"GO_REGULATION_OF_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXOCYTOSIS","description":"Any process that modulates the frequency, rate or extent of exocytosis."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway."} {"geneset":"GO_ANION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANION_TRANSMEMBRANE_TRANSPORT","description":"A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_SURFACE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_SURFACE","description":"Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface."} {"geneset":"GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL","description":"A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein."} {"geneset":"GO_RENAL_VESICLE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_VESICLE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells."} {"geneset":"GO_REGULATION_OF_BODY_FLUID_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BODY_FLUID_LEVELS","description":"Any process that modulates the levels of body fluids."} {"geneset":"GO_REGULATION_OF_HORMONE_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HORMONE_LEVELS","description":"Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action."} {"geneset":"GO_BONE_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."} {"geneset":"GO_REGULATION_OF_DEFENSE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEFENSE_RESPONSE","description":"Any process that modulates the frequency, rate or extent of a defense response."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process."} {"geneset":"GO_PYRIMIDINE_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."} {"geneset":"GO_POSITIVE_REGULATION_OF_HEART_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HEART_GROWTH","description":"Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PEPTIDE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PEPTIDE_SECRETION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion."} {"geneset":"GO_VESICLE_TARGETING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_TARGETING","description":"The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo."} {"geneset":"GO_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS","description":"Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm."} {"geneset":"GO_LAYER_FORMATION_IN_CEREBRAL_CORTEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAYER_FORMATION_IN_CEREBRAL_CORTEX","description":"The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex."} {"geneset":"GO_POSITIVE_REGULATION_OF_ACTIN_CYTOSKELETON_REORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ACTIN_CYTOSKELETON_REORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization."} {"geneset":"GO_SEX_DETERMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEX_DETERMINATION","description":"Any process that establishes and transmits the specification of sexual status of an individual organism."} {"geneset":"GO_OLIGOSACCHARIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLIGOSACCHARIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."} {"geneset":"GO_B_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_B_CELL_PROLIFERATION","description":"The expansion of a B cell population by cell division. Follows B cell activation."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA."} {"geneset":"GO_PROTEASOME_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEASOME_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a mature, active proteasome complex."} {"geneset":"GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM","description":"The directed movement of a protein to a specific location in the endoplasmic reticulum."} {"geneset":"GO_PYRIMIDINE_NUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ENDOCYTOSIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis."} {"geneset":"GO_RESPONSE_TO_POTASSIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_POTASSIUM_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus."} {"geneset":"GO_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS","description":"Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process."} {"geneset":"GO_SMALL_MOLECULE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMALL_MOLECULE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule."} {"geneset":"GO_THYMUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THYMUS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization."} {"geneset":"GO_HOMEOSTATIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOMEOSTATIC_PROCESS","description":"Any biological process involved in the maintenance of an internal steady state."} {"geneset":"GO_CEREBELLAR_CORTEX_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBELLAR_CORTEX_MORPHOGENESIS","description":"The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of cytoplasmic transport."} {"geneset":"GO_MORPHOGENESIS_OF_AN_EPITHELIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MORPHOGENESIS_OF_AN_EPITHELIUM","description":"The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube."} {"geneset":"GO_OSTEOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OSTEOBLAST_DIFFERENTIATION","description":"The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone."} {"geneset":"GO_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of striated muscle cell differentiation."} {"geneset":"GO_DEFENSE_RESPONSE_TO_VIRUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEFENSE_RESPONSE_TO_VIRUS","description":"Reactions triggered in response to the presence of a virus that act to protect the cell or organism."} {"geneset":"GO_SENSORY_PERCEPTION_OF_CHEMICAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_PERCEPTION_OF_CHEMICAL_STIMULUS","description":"The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."} {"geneset":"GO_REGULATION_OF_RUFFLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RUFFLE_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of ruffle assembly."} {"geneset":"GO_CELLULAR_PIGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_PIGMENTATION","description":"The deposition or aggregation of coloring matter in a cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis."} {"geneset":"GO_VACUOLAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLAR_TRANSPORT","description":"The directed movement of substances into, out of or within a vacuole."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION","description":"Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL","description":"Any process that activates or increases the frequency, rate or extent of viral release from host cell."} {"geneset":"GO_LEUKOCYTE_MEDIATED_CYTOTOXICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_MEDIATED_CYTOTOXICITY","description":"The directed killing of a target cell by a leukocyte."} {"geneset":"GO_POSITIVE_REGULATION_OF_VACUOLAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VACUOLAR_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of vacuolar transport."} {"geneset":"GO_POSITIVE_REGULATION_OF_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LYASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."} {"geneset":"GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK_BY_PHOTOPERIOD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK_BY_PHOTOPERIOD","description":"The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night)."} {"geneset":"GO_SUPEROXIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUPEROXIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species."} {"geneset":"GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving organic hydroxy compound."} {"geneset":"GO_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING","description":"Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA."} {"geneset":"GO_PHOTOTRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTOTRANSDUCTION","description":"The sequence of reactions within a cell required to convert absorbed photons into a molecular signal."} {"geneset":"GO_REGULATION_OF_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIGASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6."} {"geneset":"GO_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced."} {"geneset":"GO_SULFATE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFATE_TRANSPORT","description":"The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_RESPONSE_TO_FOOD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_FOOD","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat."} {"geneset":"GO_REGULATION_OF_PROTEIN_INSERTION_INTO_MITOCHONDRIAL_MEMBRANE_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_INSERTION_INTO_MITOCHONDRIAL_MEMBRANE_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway."} {"geneset":"GO_TELOMERE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins."} {"geneset":"GO_IMMUNE_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNE_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process."} {"geneset":"GO_CAMP_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CAMP_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."} {"geneset":"GO_ALPHA_AMINO_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALPHA_AMINO_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid."} {"geneset":"GO_CELLULAR_COMPONENT_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_COMPONENT_MAINTENANCE","description":"The organization process that preserves a cellular component in a stable functional or structural state."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_CONTRACTION","description":"Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction."} {"geneset":"GO_FC_GAMMA_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FC_GAMMA_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region."} {"geneset":"GO_RRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes."} {"geneset":"GO_RESPIRATORY_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPIRATORY_SYSTEM_PROCESS","description":"A system process carried out by the organs and tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange."} {"geneset":"GO_NEUROTRANSMITTER_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTRANSMITTER_TRANSPORT","description":"The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell."} {"geneset":"GO_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of T-helper cell differentiation."} {"geneset":"GO_REGULATION_OF_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity."} {"geneset":"GO_PH_REDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PH_REDUCTION","description":"Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRIGLYCERIDE_LIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRIGLYCERIDE_LIPASE_ACTIVITY","description":"Any process that increases the activity of triglyceride lipase."} {"geneset":"GO_MONOSACCHARIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOSACCHARIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms."} {"geneset":"GO_POSITIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of mRNA metabolic process."} {"geneset":"GO_RESPONSE_TO_FUNGICIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_FUNGICIDE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi."} {"geneset":"GO_NEGATIVE_REGULATION_BY_HOST_OF_VIRAL_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_BY_HOST_OF_VIRAL_TRANSCRIPTION","description":"Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription."} {"geneset":"GO_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of EGF-activated receptor activity."} {"geneset":"GO_PROTEIN_NEDDYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_NEDDYLATION","description":"Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein."} {"geneset":"GO_POTASSIUM_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POTASSIUM_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell."} {"geneset":"GO_HORMONE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HORMONE_TRANSPORT","description":"The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION","description":"Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."} {"geneset":"GO_INORGANIC_ANION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INORGANIC_ANION_TRANSPORT","description":"The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage."} {"geneset":"GO_CARBOHYDRATE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_PHOSPHORYLATION","description":"The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y."} {"geneset":"GO_PROTEIN_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_IMPORT","description":"The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event."} {"geneset":"GO_NUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."} {"geneset":"GO_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."} {"geneset":"GO_MAMMARY_GLAND_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAMMARY_GLAND_EPITHELIAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland."} {"geneset":"GO_CELLULAR_RESPONSE_TO_GAMMA_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_GAMMA_RADIATION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum."} {"geneset":"GO_REGULATION_OF_HEAT_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEAT_GENERATION","description":"Any process that modulates the rate or extent of heat generation."} {"geneset":"GO_REGULATION_OF_FIBROBLAST_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FIBROBLAST_MIGRATION","description":"Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."} {"geneset":"GO_INDUCTION_OF_POSITIVE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INDUCTION_OF_POSITIVE_CHEMOTAXIS","description":"Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."} {"geneset":"GO_REGENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGENERATION","description":"The regrowth of a lost or destroyed body part, such as an organ or tissue."} {"geneset":"GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered."} {"geneset":"GO_REGULATION_OF_TRANSLATIONAL_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSLATIONAL_ELONGATION","description":"Any process that modulates the frequency, rate, extent or accuracy of translational elongation."} {"geneset":"GO_CELL_MATRIX_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MATRIX_ADHESION","description":"The binding of a cell to the extracellular matrix via adhesion molecules."} {"geneset":"GO_PITUITARY_GLAND_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PITUITARY_GLAND_DEVELOPMENT","description":"The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands."} {"geneset":"GO_MATING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATING","description":"The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes."} {"geneset":"GO_DEVELOPMENTAL_INDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENTAL_INDUCTION","description":"A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)."} {"geneset":"GO_REGULATION_OF_TRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSFERASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process."} {"geneset":"GO_CHROMOSOME_SEPARATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_SEPARATION","description":"The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II)."} {"geneset":"GO_GANGLIOSIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GANGLIOSIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues."} {"geneset":"GO_TISSUE_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TISSUE_HOMEOSTASIS","description":"A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function."} {"geneset":"GO_ANTIGEN_PROCESSING_AND_PRESENTATION_VIA_MHC_CLASS_IB","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_PROCESSING_AND_PRESENTATION_VIA_MHC_CLASS_IB","description":"The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families."} {"geneset":"GO_GAMMA_AMINOBUTYRIC_ACID_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GAMMA_AMINOBUTYRIC_ACID_SIGNALING_PATHWAY","description":"The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor."} {"geneset":"GO_POSITIVE_REGULATION_OF_STEROL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STEROL_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS","description":"An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus."} {"geneset":"GO_CELL_CYCLE_ARREST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CYCLE_ARREST","description":"A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M)."} {"geneset":"GO_THYROID_HORMONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THYROID_HORMONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine."} {"geneset":"GO_APOPTOTIC_CELL_CLEARANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APOPTOTIC_CELL_CLEARANCE","description":"The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte."} {"geneset":"GO_MODIFICATION_OF_MORPHOLOGY_OR_PHYSIOLOGY_OF_OTHER_ORGANISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODIFICATION_OF_MORPHOLOGY_OR_PHYSIOLOGY_OF_OTHER_ORGANISM","description":"The process in which an organism effects a change in the structure or processes of a second organism."} {"geneset":"GO_RIBOSOME_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOME_ASSEMBLY","description":"The aggregation, arrangement and bonding together of the mature ribosome and of its subunits."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_DEPOLYMERIZATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization."} {"geneset":"GO_DNA_LIGATION_INVOLVED_IN_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_LIGATION_INVOLVED_IN_DNA_REPAIR","description":"The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair."} {"geneset":"GO_REGULATION_OF_CELL_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_JUNCTION_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of cell junction assembly."} {"geneset":"GO_HYPEROSMOTIC_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYPEROSMOTIC_RESPONSE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell."} {"geneset":"GO_REGULATION_OF_SMAD_PROTEIN_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SMAD_PROTEIN_IMPORT_INTO_NUCLEUS","description":"Any process that modulates the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity."} {"geneset":"GO_ARTERY_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARTERY_DEVELOPMENT","description":"The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed."} {"geneset":"GO_PROTEIN_DEALKYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DEALKYLATION","description":"The removal of an alkyl group from a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DENDRITE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DENDRITE_MORPHOGENESIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."} {"geneset":"GO_EXTRACELLULAR_MATRIX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_MATRIX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of the extracellular matrix."} {"geneset":"GO_POSTREPLICATION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSTREPLICATION_REPAIR","description":"The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication."} {"geneset":"GO_SKELETAL_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKELETAL_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)."} {"geneset":"GO_ORGANOPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANOPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound."} {"geneset":"GO_CARDIAC_MYOFIBRIL_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_MYOFIBRIL_ASSEMBLY","description":"The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells."} {"geneset":"GO_REGULATION_OF_HEART_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEART_CONTRACTION","description":"Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body."} {"geneset":"GO_CELLULAR_AMINO_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_AMINO_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents."} {"geneset":"GO_CRANIAL_NERVE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CRANIAL_NERVE_MORPHOGENESIS","description":"The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."} {"geneset":"GO_ACTIVATION_OF_JUN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_JUN_KINASE_ACTIVITY","description":"The initiation of the activity of the inactive enzyme JUN kinase (JNK)."} {"geneset":"GO_REGULATION_OF_BROWN_FAT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BROWN_FAT_CELL_DIFFERENTIATION","description":"Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."} {"geneset":"GO_FIBRIL_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FIBRIL_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of fibrils, insoluble fibrous aggregates consisting of polysaccharides and/or proteins."} {"geneset":"GO_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."} {"geneset":"GO_MONOVALENT_INORGANIC_CATION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOVALENT_INORGANIC_CATION_TRANSPORT","description":"The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage."} {"geneset":"GO_RELAXATION_OF_CARDIAC_MUSCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RELAXATION_OF_CARDIAC_MUSCLE","description":"The process in which the extent of cardiac muscle contraction is reduced."} {"geneset":"GO_POSITIVE_REGULATION_OF_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BEHAVIOR","description":"Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."} {"geneset":"GO_CALCIUM_MEDIATED_SIGNALING_USING_INTRACELLULAR_CALCIUM_SOURCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_MEDIATED_SIGNALING_USING_INTRACELLULAR_CALCIUM_SOURCE","description":"A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response."} {"geneset":"GO_NEURAL_TUBE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURAL_TUBE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium."} {"geneset":"GO_POLYSACCHARIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYSACCHARIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."} {"geneset":"GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION","description":"Any process that modulates the frequency, rate or extent of intracellular signal transduction."} {"geneset":"GO_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."} {"geneset":"GO_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION","description":"Any process that activates or increases the rate or extent of T cell proliferation."} {"geneset":"GO_MULTICELLULAR_ORGANISMAL_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISMAL_MOVEMENT","description":"Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism."} {"geneset":"GO_CLATHRIN_COAT_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COAT_ASSEMBLY","description":"The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MEIOTIC_NUCLEAR_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MEIOTIC_NUCLEAR_DIVISION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis."} {"geneset":"GO_VASCULAR_SMOOTH_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASCULAR_SMOOTH_MUSCLE_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NITROGEN_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NITROGEN_COMPOUND_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds."} {"geneset":"GO_DNA_INTEGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_INTEGRATION","description":"The process in which a segment of DNA is incorporated into another, usually larger, DNA molecule such as a chromosome."} {"geneset":"GO_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_ACTIVATION","description":"A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand."} {"geneset":"GO_REGULATION_OF_MYELINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MYELINATION","description":"Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons."} {"geneset":"GO_NEGATIVE_REGULATION_OF_JUN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_JUN_KINASE_ACTIVITY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity."} {"geneset":"GO_REGULATION_OF_AXON_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_AXON_GUIDANCE","description":"Any process that modulates the frequency, rate or extent of axon guidance."} {"geneset":"GO_REGULATION_OF_DOPAMINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DOPAMINE_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of dopamine."} {"geneset":"GO_RESPONSE_TO_COPPER_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_COPPER_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus."} {"geneset":"GO_REGULATION_OF_CIRCADIAN_SLEEP_WAKE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CIRCADIAN_SLEEP_WAKE_CYCLE","description":"Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process."} {"geneset":"GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION","description":"Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences."} {"geneset":"GO_RESPONSE_TO_AXON_INJURY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_AXON_INJURY","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus."} {"geneset":"GO_REGULATION_OF_VACUOLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VACUOLE_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole."} {"geneset":"GO_CIRCADIAN_REGULATION_OF_GENE_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CIRCADIAN_REGULATION_OF_GENE_EXPRESSION","description":"Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours."} {"geneset":"GO_RETINOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A."} {"geneset":"GO_OXALOACETATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXALOACETATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY","description":"Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EXOCYTOSIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis."} {"geneset":"GO_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands."} {"geneset":"GO_REGULATION_OF_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_WNT_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly."} {"geneset":"GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN","description":"The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein."} {"geneset":"GO_HIPPO_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HIPPO_SIGNALING","description":"The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","description":"Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."} {"geneset":"GO_REGULATION_OF_MEMBRANE_DEPOLARIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEMBRANE_DEPOLARIZATION","description":"Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive."} {"geneset":"GO_AMINO_SUGAR_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_SUGAR_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group."} {"geneset":"GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."} {"geneset":"GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME","description":"Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_DIGESTIVE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DIGESTIVE_SYSTEM_PROCESS","description":"Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."} {"geneset":"GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE","description":"A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered."} {"geneset":"GO_TETRAPYRROLE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TETRAPYRROLE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."} {"geneset":"GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a nucleoside phosphate."} {"geneset":"GO_PROTEIN_LIPID_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LIPID_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex."} {"geneset":"GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT","description":"Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_DETECTION_OF_OTHER_ORGANISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_OTHER_ORGANISM","description":"The series of events in which a stimulus from another organism is received and converted into a molecular signal."} {"geneset":"GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL","description":"The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell."} {"geneset":"GO_G_PROTEIN_COUPLED_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_NEURAL_RETINA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURAL_RETINA_DEVELOPMENT","description":"The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."} {"geneset":"GO_CLEAVAGE_INVOLVED_IN_RRNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLEAVAGE_INVOLVED_IN_RRNA_PROCESSING","description":"Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule."} {"geneset":"GO_REGULATION_OF_EXIT_FROM_MITOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXIT_FROM_MITOSIS","description":"Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity."} {"geneset":"GO_FORELIMB_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FORELIMB_MORPHOGENESIS","description":"The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human."} {"geneset":"GO_ASPARTATE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASPARTATE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."} {"geneset":"GO_MANGANESE_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MANGANESE_ION_TRANSPORT","description":"The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_HISTONE_H3_K4_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HISTONE_H3_K4_METHYLATION","description":"Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3."} {"geneset":"GO_NEURON_PROJECTION_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_DEVELOPMENT","description":"The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."} {"geneset":"GO_MALE_GAMETE_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MALE_GAMETE_GENERATION","description":"Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction."} {"geneset":"GO_POSITIVE_REGULATION_OF_FIBROBLAST_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_FIBROBLAST_MIGRATION","description":"Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress."} {"geneset":"GO_CHAPERONE_MEDIATED_PROTEIN_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHAPERONE_MEDIATED_PROTEIN_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex."} {"geneset":"GO_ORGANELLE_TRANSPORT_ALONG_MICROTUBULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_TRANSPORT_ALONG_MICROTUBULE","description":"The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination."} {"geneset":"GO_CHONDROCYTE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHONDROCYTE_DEVELOPMENT","description":"The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."} {"geneset":"GO_MEMBRANE_RAFT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_RAFT_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."} {"geneset":"GO_MITOTIC_SISTER_CHROMATID_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_SISTER_CHROMATID_SEGREGATION","description":"The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets."} {"geneset":"GO_MICROTUBULE_NUCLEATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_NUCLEATION","description":"The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)."} {"geneset":"GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE","description":"The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response."} {"geneset":"GO_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION","description":"Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system."} {"geneset":"GO_REGULATION_OF_MEMBRANE_LIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEMBRANE_LIPID_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of membrane lipid metabolic process."} {"geneset":"GO_XENOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_XENOPHAGY","description":"The macroautophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents."} {"geneset":"GO_DRUG_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DRUG_TRANSMEMBRANE_TRANSPORT","description":"The process in which a drug is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_MEMBRANE_DEPOLARIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MEMBRANE_DEPOLARIZATION","description":"Any process that activates or increases the frequency, rate or extent of membrane depolarization."} {"geneset":"GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response."} {"geneset":"GO_REGULATION_OF_PROTEIN_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_POLYMERIZATION","description":"Any process that modulates the frequency, rate or extent of the process of creating protein polymers."} {"geneset":"GO_REGULATION_OF_PROTEIN_TARGETING_TO_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_TARGETING_TO_MEMBRANE","description":"Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."} {"geneset":"GO_KIDNEY_EPITHELIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KIDNEY_EPITHELIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."} {"geneset":"GO_HISTONE_H2A_UBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H2A_UBIQUITINATION","description":"The modification of histone H2A by addition of one or more ubiquitin groups."} {"geneset":"GO_TOOTH_MINERALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOOTH_MINERALIZATION","description":"The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum."} {"geneset":"GO_REGULATION_OF_HAIR_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HAIR_CYCLE","description":"Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BONE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BONE_REMODELING","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling."} {"geneset":"GO_POSITIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS","description":"Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."} {"geneset":"GO_ESTABLISHMENT_OF_MITOTIC_SPINDLE_ORIENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_MITOTIC_SPINDLE_ORIENTATION","description":"A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION","description":"Any process that activates or increases the frequency, rate or extent of protein oligomerization."} {"geneset":"GO_SPINDLE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINDLE_CHECKPOINT","description":"A cell cycle checkpoint that originates from the mitotic or meiotic spindle."} {"geneset":"GO_POSITIVE_REGULATION_OF_STAT_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STAT_CASCADE","description":"Any process that activates or increases the frequency, rate or extent of STAT cascade."} {"geneset":"GO_LEUKOTRIENE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOTRIENE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid."} {"geneset":"GO_POSITIVE_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING","description":"Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading."} {"geneset":"GO_POSITIVE_REGULATION_OF_THYMOCYTE_AGGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_THYMOCYTE_AGGREGATION","description":"Any process that activates or increases the frequency, rate or extent of thymocyte aggregation."} {"geneset":"GO_CATECHOLAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATECHOLAMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY","description":"Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components."} {"geneset":"GO_BLASTOCYST_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLASTOCYST_FORMATION","description":"The initial formation of a blastocyst from a solid ball of cells known as a morula."} {"geneset":"GO_REGULATION_OF_WATER_LOSS_VIA_SKIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_WATER_LOSS_VIA_SKIN","description":"A process that modulates the rate or extent of water loss from an organism via the skin."} {"geneset":"GO_NEGATIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway."} {"geneset":"GO_CELL_DIFFERENTIATION_INVOLVED_IN_METANEPHROS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DIFFERENTIATION_INVOLVED_IN_METANEPHROS_DEVELOPMENT","description":"The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state."} {"geneset":"GO_POSITIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process."} {"geneset":"GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development."} {"geneset":"GO_MAGNESIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAGNESIUM_ION_TRANSPORT","description":"The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_PYRIMIDINE_RIBONUCLEOSIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_RIBONUCLEOSIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CENTROSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CENTROSOME","description":"A process in which a protein is transported to, or maintained at, the centrosome."} {"geneset":"GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION","description":"Any process that activates or increases the rate or extent of B cell proliferation."} {"geneset":"GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION","description":"Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."} {"geneset":"GO_MUSCLE_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_CELL_PROLIFERATION","description":"The expansion of a muscle cell population by cell division."} {"geneset":"GO_VENTRAL_SPINAL_CORD_INTERNEURON_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRAL_SPINAL_CORD_INTERNEURON_SPECIFICATION","description":"The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway."} {"geneset":"GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of amino acids, organic acids containing one or more amino substituents across a membrane by means of some agent such as a transporter or pore."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ACID_CHEMICAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ACID_CHEMICAL","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."} {"geneset":"GO_PHAGOCYTOSIS_ENGULFMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOCYTOSIS_ENGULFMENT","description":"The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis."} {"geneset":"GO_REGULATION_OF_TOLERANCE_INDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TOLERANCE_INDUCTION","description":"Any process that modulates the frequency, rate, or extent of tolerance induction."} {"geneset":"GO_REGULATION_OF_CORTICOSTEROID_HORMONE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CORTICOSTEROID_HORMONE_SECRETION","description":"Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion."} {"geneset":"GO_CELLULAR_SENESCENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_SENESCENCE","description":"A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest."} {"geneset":"GO_SULFATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFATION","description":"The addition of a sulfate group to a molecule."} {"geneset":"GO_REGULATION_OF_MEIOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEIOTIC_CELL_CYCLE","description":"Any process that modulates the rate or extent of progression through the meiotic cell cycle."} {"geneset":"GO_DNA_DEALKYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DEALKYLATION","description":"The removal of an alkyl group from one or more nucleotides within an DNA molecule."} {"geneset":"GO_ACTIN_FILAMENT_BASED_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT_BASED_MOVEMENT","description":"Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins."} {"geneset":"GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION","description":"Any process that activates or increases the rate or extent of epithelial cell proliferation."} {"geneset":"GO_SARCOMERE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SARCOMERE_ORGANIZATION","description":"The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."} {"geneset":"GO_POSITIVE_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY","description":"Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity."} {"geneset":"GO_OVULATION_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OVULATION_CYCLE","description":"The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process."} {"geneset":"GO_VENTRICULAR_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRICULAR_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus."} {"geneset":"GO_ADULT_LOCOMOTORY_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADULT_LOCOMOTORY_BEHAVIOR","description":"Locomotory behavior in a fully developed and mature organism."} {"geneset":"GO_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of activated T cell proliferation."} {"geneset":"GO_POSITIVE_REGULATION_OF_HOMEOSTATIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HOMEOSTATIC_PROCESS","description":"Any process that activates or increases the frequency, rate, or extent of a homeostatic process."} {"geneset":"GO_RESPONSE_TO_GRAVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_GRAVITY","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus."} {"geneset":"GO_REGULATION_OF_IMMUNOGLOBULIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_IMMUNOGLOBULIN_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of immunoglobulins from a cell."} {"geneset":"GO_ACETYL_COA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACETYL_COA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis."} {"geneset":"GO_CREATINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CREATINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle."} {"geneset":"GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS","description":"Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component."} {"geneset":"GO_POSITIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION","description":"Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."} {"geneset":"GO_IRON_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IRON_ION_TRANSPORT","description":"The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RECEPTOR_BINDING","description":"Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor."} {"geneset":"GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT","description":"Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation."} {"geneset":"GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_10_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_10_SECRETION","description":"Any process that modulates the frequency, rate or extent of interleukin-10 secretion."} {"geneset":"GO_REGULATION_OF_LAMELLIPODIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LAMELLIPODIUM_ASSEMBLY","description":"Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."} {"geneset":"GO_CELLULAR_KETONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_KETONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."} {"geneset":"GO_CRANIAL_NERVE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CRANIAL_NERVE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."} {"geneset":"GO_WNT_SIGNALING_PATHWAY_CALCIUM_MODULATING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WNT_SIGNALING_PATHWAY_CALCIUM_MODULATING_PATHWAY","description":"The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)."} {"geneset":"GO_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_CELL_PROLIFERATION_IN_FOREBRAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PROLIFERATION_IN_FOREBRAIN","description":"The creation of greater cell numbers in the forebrain due to cell division of progenitor cells."} {"geneset":"GO_RESPONSE_TO_MURAMYL_DIPEPTIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MURAMYL_DIPEPTIDE","description":"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan."} {"geneset":"GO_REGULATION_OF_POSITIVE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_POSITIVE_CHEMOTAXIS","description":"Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."} {"geneset":"GO_REGULATION_OF_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway."} {"geneset":"GO_MEMBRANE_LIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_LIPID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEUROBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEUROBLAST_PROLIFERATION","description":"Any process that activates or increases the rate of neuroblast proliferation."} {"geneset":"GO_CARTILAGE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARTILAGE_MORPHOGENESIS","description":"The process in which the anatomical structures of cartilage are generated and organized."} {"geneset":"GO_PEPTIDE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_SECRETION","description":"The controlled release of a peptide from a cell or a tissue."} {"geneset":"GO_THIOESTER_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THIOESTER_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE","description":"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."} {"geneset":"GO_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides."} {"geneset":"GO_PURINE_RIBONUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_RIBONUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."} {"geneset":"GO_PEPTIDYL_CYSTEINE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_CYSTEINE_MODIFICATION","description":"The modification of peptidyl-cysteine."} {"geneset":"GO_LEUKOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."} {"geneset":"GO_RESPONSE_TO_EXOGENOUS_DSRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_EXOGENOUS_DSRNA","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus."} {"geneset":"GO_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM","description":"The process in which the anatomical structures of embryonic epithelia are generated and organized."} {"geneset":"GO_SKELETAL_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKELETAL_MUSCLE_CONTRACTION","description":"A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control."} {"geneset":"GO_POSITIVE_REGULATION_OF_HORMONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HORMONE_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone."} {"geneset":"GO_TONGUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TONGUE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech."} {"geneset":"GO_BONE_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_GROWTH","description":"The increase in size or mass of a bone that contributes to the shaping of that bone."} {"geneset":"GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION","description":"Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament."} {"geneset":"GO_UV_PROTECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UV_PROTECTION","description":"Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV."} {"geneset":"GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL","description":"A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein."} {"geneset":"GO_REGULATION_OF_NITRIC_OXIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NITRIC_OXIDE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide."} {"geneset":"GO_PHOSPHATIDYLGLYCEROL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLGLYCEROL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes."} {"geneset":"GO_PYRIMIDINE_NUCLEOSIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOSIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."} {"geneset":"GO_TRANSLATIONAL_TERMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATIONAL_TERMINATION","description":"The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)."} {"geneset":"GO_CYTOKINETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINETIC_PROCESS","description":"A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells)."} {"geneset":"GO_ENDOCARDIAL_CUSHION_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCARDIAL_CUSHION_MORPHOGENESIS","description":"The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."} {"geneset":"GO_REGULATION_OF_INNATE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INNATE_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection."} {"geneset":"GO_VESICLE_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_MEDIATED_TRANSPORT","description":"A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane."} {"geneset":"GO_INTERLEUKIN_1_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERLEUKIN_1_PRODUCTION","description":"The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."} {"geneset":"GO_MODULATION_BY_HOST_OF_VIRAL_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODULATION_BY_HOST_OF_VIRAL_PROCESS","description":"A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected."} {"geneset":"GO_REGULATION_OF_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_REPAIR","description":"Any process that modulates the frequency, rate or extent of DNA repair."} {"geneset":"GO_REGULATION_OF_MEMBRANE_LIPID_DISTRIBUTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEMBRANE_LIPID_DISTRIBUTION","description":"Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane."} {"geneset":"GO_REFLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REFLEX","description":"An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness."} {"geneset":"GO_LEUKOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_MEDIATED_IMMUNITY","description":"Any process involved in the carrying out of an immune response by a leukocyte."} {"geneset":"GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SERINE_TYPE_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SERINE_TYPE_PEPTIDASE_ACTIVITY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY","description":"A process in which a protein is transported to, or maintained in, the cell periphery."} {"geneset":"GO_REGULATION_OF_PROTEIN_GLYCOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_GLYCOSYLATION","description":"Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."} {"geneset":"GO_NEGATIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells."} {"geneset":"GO_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of muscle tissue development."} {"geneset":"GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication."} {"geneset":"GO_REGULATION_OF_LEUKOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LEUKOCYTE_MIGRATION","description":"Any process that modulates the frequency, rate, or extent of leukocyte migration."} {"geneset":"GO_ORGAN_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGAN_MATURATION","description":"A developmental process, independent of morphogenetic (shape) change, that is required for an organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions."} {"geneset":"GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HEAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HEAT","description":"Any process that modulates the frequency, rate or extent of cellular response to heat."} {"geneset":"GO_POSITIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE","description":"Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response."} {"geneset":"GO_GASTRULATION_WITH_MOUTH_FORMING_SECOND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GASTRULATION_WITH_MOUTH_FORMING_SECOND","description":"A gastrulation process in which the initial invagination becomes the anus and the mouth forms second."} {"geneset":"GO_ENDOCARDIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCARDIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."} {"geneset":"GO_ENDOTHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOTHELIAL_CELL_DIFFERENTIATION","description":"The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell."} {"geneset":"GO_INSEMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INSEMINATION","description":"The introduction of semen or sperm into the genital tract of a female."} {"geneset":"GO_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_PHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_PHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position."} {"geneset":"GO_CYCLIC_NUCLEOTIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIC_NUCLEOTIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."} {"geneset":"GO_RESPONSE_TO_EPIDERMAL_GROWTH_FACTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_EPIDERMAL_GROWTH_FACTOR","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."} {"geneset":"GO_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."} {"geneset":"GO_POSITIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate."} {"geneset":"GO_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WNT_SIGNALING_PATHWAY","description":"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state."} {"geneset":"GO_REGULATION_OF_NEUROTRANSMITTER_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUROTRANSMITTER_LEVELS","description":"Any process that modulates levels of neurotransmitter."} {"geneset":"GO_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE","description":"Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade."} {"geneset":"GO_PEPTIDYL_ARGININE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_ARGININE_MODIFICATION","description":"The modification of peptidyl-arginine."} {"geneset":"GO_SPECIFICATION_OF_ORGAN_IDENTITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPECIFICATION_OF_ORGAN_IDENTITY","description":"The regionalization process in which the identity of an organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."} {"geneset":"GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines."} {"geneset":"GO_RRNA_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_TRANSCRIPTION","description":"The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template."} {"geneset":"GO_POSITIVE_REGULATION_OF_LIPID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LIPID_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ANATOMICAL_STRUCTURE_ARRANGEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANATOMICAL_STRUCTURE_ARRANGEMENT","description":"The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."} {"geneset":"GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","description":"A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."} {"geneset":"GO_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION","description":"The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor."} {"geneset":"GO_SINGLE_ORGANISM_MEMBRANE_BUDDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_ORGANISM_MEMBRANE_BUDDING","description":"A membrane budding which involves only one organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade."} {"geneset":"GO_SPONGIOTROPHOBLAST_LAYER_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPONGIOTROPHOBLAST_LAYER_DEVELOPMENT","description":"The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."} {"geneset":"GO_HISTONE_H2A_MONOUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H2A_MONOUBIQUITINATION","description":"The modification of histone H2A by addition of a single ubiquitin group."} {"geneset":"GO_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of extracellular matrix organization."} {"geneset":"GO_CELL_DIFFERENTIATION_IN_SPINAL_CORD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DIFFERENTIATION_IN_SPINAL_CORD","description":"The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate."} {"geneset":"GO_MITOTIC_G2_M_TRANSITION_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_G2_M_TRANSITION_CHECKPOINT","description":"A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_8_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_8_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion."} {"geneset":"GO_PYRIMIDINE_NUCLEOBASE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOBASE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases."} {"geneset":"GO_RNA_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_METHYLATION","description":"Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor."} {"geneset":"GO_PURINE_CONTAINING_COMPOUND_SALVAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_CONTAINING_COMPOUND_SALVAGE","description":"Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis."} {"geneset":"GO_INNER_EAR_RECEPTOR_STEREOCILIUM_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNER_EAR_RECEPTOR_STEREOCILIUM_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport."} {"geneset":"GO_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of phospholipid metabolic process."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS","description":"Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus."} {"geneset":"GO_AXON_REGENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXON_REGENERATION","description":"The regrowth of axons following their loss or damage."} {"geneset":"GO_MICROTUBULE_BASED_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_BASED_PROCESS","description":"Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins."} {"geneset":"GO_CALCIUM_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_MEDIATED_SIGNALING","description":"Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions."} {"geneset":"GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_CLEARANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_CLEARANCE","description":"The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."} {"geneset":"GO_SPERM_MOTILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERM_MOTILITY","description":"Any process involved in the controlled movement of a sperm cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."} {"geneset":"GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_BINDING","description":"Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."} {"geneset":"GO_NUCLEOTIDE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_TRANSPORT","description":"The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell."} {"geneset":"GO_REGULATION_OF_HAIR_FOLLICLE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HAIR_FOLLICLE_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of hair follicle development."} {"geneset":"GO_CRISTAE_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CRISTAE_FORMATION","description":"The assembly of cristae, the inwards folds of the inner mitochondrial membrane."} {"geneset":"GO_SYNAPTIC_VESICLE_RECYCLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_VESICLE_RECYCLING","description":"The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides."} {"geneset":"GO_DORSAL_VENTRAL_PATTERN_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DORSAL_VENTRAL_PATTERN_FORMATION","description":"The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."} {"geneset":"GO_REGULATION_OF_VITAMIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VITAMIN_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."} {"geneset":"GO_AEROBIC_RESPIRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AEROBIC_RESPIRATION","description":"The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor."} {"geneset":"GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms."} {"geneset":"GO_SEQUESTERING_OF_METAL_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEQUESTERING_OF_METAL_ION","description":"The process of binding or confining metal ions such that they are separated from other components of a biological system."} {"geneset":"GO_COPPER_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COPPER_ION_TRANSPORT","description":"The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_MEMBRANE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a membrane."} {"geneset":"GO_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","description":"Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."} {"geneset":"GO_LIPID_DIGESTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_DIGESTION","description":"The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."} {"geneset":"GO_POSITIVE_REGULATION_OF_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE","description":"Any cell cycle regulatory process that promotes the commitment of a cell from G1 to S phase of the mitotic cell cycle."} {"geneset":"GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION","description":"Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form."} {"geneset":"GO_NEUROMUSCULAR_PROCESS_CONTROLLING_BALANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROMUSCULAR_PROCESS_CONTROLLING_BALANCE","description":"Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors."} {"geneset":"GO_ORGAN_OR_TISSUE_SPECIFIC_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGAN_OR_TISSUE_SPECIFIC_IMMUNE_RESPONSE","description":"An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_REGULATION_OF_THE_RELEASE_OF_SEQUESTERED_CALCIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_REGULATION_OF_THE_RELEASE_OF_SEQUESTERED_CALCIUM_ION","description":"Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ORGANELLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ORGANELLE_ASSEMBLY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly."} {"geneset":"GO_RESPONSE_TO_INTERFERON_BETA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INTERFERON_BETA","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon."} {"geneset":"GO_REGULATION_OF_ORGAN_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ORGAN_FORMATION","description":"Any process that modulates the rate, frequency or extent of organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment."} {"geneset":"GO_FOREBRAIN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOREBRAIN_DEVELOPMENT","description":"The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)."} {"geneset":"GO_RHODOPSIN_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RHODOPSIN_MEDIATED_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response."} {"geneset":"GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","description":"Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase."} {"geneset":"GO_REGULATION_OF_MESONEPHROS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MESONEPHROS_DEVELOPMENT","description":"Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving carbohydrate derivative."} {"geneset":"GO_REGULATION_OF_CHROMATIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHROMATIN_BINDING","description":"Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."} {"geneset":"GO_STEM_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEM_CELL_PROLIFERATION","description":"The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."} {"geneset":"GO_NAD_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NAD_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid."} {"geneset":"GO_REGULATION_OF_EXTRACELLULAR_MATRIX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXTRACELLULAR_MATRIX_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of extracellular matrix assembly."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_LYSOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_LYSOSOME","description":"A process in which a protein is transported to, or maintained in, a location within a lysosome."} {"geneset":"GO_MRNA_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_MODIFICATION","description":"The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically."} {"geneset":"GO_SOMATIC_DIVERSIFICATION_OF_IMMUNOGLOBULINS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMATIC_DIVERSIFICATION_OF_IMMUNOGLOBULINS","description":"The somatic process that results in the generation of sequence diversity of immunoglobulins."} {"geneset":"GO_ERBB2_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERBB2_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair."} {"geneset":"GO_AMEBOIDAL_TYPE_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMEBOIDAL_TYPE_CELL_MIGRATION","description":"Cell migration that is accomplished by extension and retraction of a pseudopodium."} {"geneset":"GO_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."} {"geneset":"GO_SPINAL_CORD_MOTOR_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINAL_CORD_MOTOR_NEURON_DIFFERENTIATION","description":"The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate."} {"geneset":"GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)."} {"geneset":"GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure."} {"geneset":"GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."} {"geneset":"GO_DICARBOXYLIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DICARBOXYLIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process."} {"geneset":"GO_REGULATION_OF_ENERGY_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENERGY_HOMEOSTASIS","description":"Any process that modulates the frequency, rate or extent of energy homeostasis."} {"geneset":"GO_REGULATION_OF_MEMBRANE_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEMBRANE_POTENTIAL","description":"Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA","description":"Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."} {"geneset":"GO_PEPTIDYL_PROLINE_HYDROXYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_PROLINE_HYDROXYLATION","description":"The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline."} {"geneset":"GO_MULTICELLULAR_ORGANISMAL_RESPONSE_TO_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISMAL_RESPONSE_TO_STRESS","description":"Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction."} {"geneset":"GO_ESTABLISHMENT_OF_LOCALIZATION_BY_MOVEMENT_ALONG_MICROTUBULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_LOCALIZATION_BY_MOVEMENT_ALONG_MICROTUBULE","description":"The movement of organelles or other particles from one location in the cell to another along microtubules."} {"geneset":"GO_AMINO_ACID_BETAINE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_ACID_BETAINE_TRANSPORT","description":"The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_AMMONIUM_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMMONIUM_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of ammonium across a membrane by means of some agent such as a transporter or pore. Ammonium is the cation NH4+."} {"geneset":"GO_REGULATION_OF_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GROWTH","description":"Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development."} {"geneset":"GO_CATION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_TRANSPORT","description":"The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_GABAERGIC_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GABAERGIC_NEURON_DIFFERENTIATION","description":"The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron."} {"geneset":"GO_MACROAUTOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROAUTOPHAGY","description":"The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded."} {"geneset":"GO_FATTY_ACID_BETA_OXIDATION_USING_ACYL_COA_DEHYDROGENASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_BETA_OXIDATION_USING_ACYL_COA_DEHYDROGENASE","description":"A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."} {"geneset":"GO_MEMBRANE_DOCKING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_DOCKING","description":"The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere."} {"geneset":"GO_EXCITATORY_POSTSYNAPTIC_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXCITATORY_POSTSYNAPTIC_POTENTIAL","description":"A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."} {"geneset":"GO_GLUTAMINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."} {"geneset":"GO_REGULATION_OF_NUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids."} {"geneset":"GO_RESPONSE_TO_INORGANIC_SUBSTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INORGANIC_SUBSTANCE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HISTONE_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HISTONE_ACETYLATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein."} {"geneset":"GO_PHAGOLYSOSOME_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOLYSOSOME_ASSEMBLY","description":"The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome."} {"geneset":"GO_MODULATION_BY_SYMBIONT_OF_HOST_CELLULAR_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODULATION_BY_SYMBIONT_OF_HOST_CELLULAR_PROCESS","description":"Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism."} {"geneset":"GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT","description":"Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell."} {"geneset":"GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of organonitrogen compound."} {"geneset":"GO_REGULATION_OF_ASTROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ASTROCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of astrocyte differentiation."} {"geneset":"GO_REGULATION_OF_HYDROGEN_PEROXIDE_INDUCED_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HYDROGEN_PEROXIDE_INDUCED_CELL_DEATH","description":"Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced cell death."} {"geneset":"GO_ADP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_PROLIFERATION","description":"Any process that activates or increases the rate or extent of cell proliferation."} {"geneset":"GO_REGULATION_OF_SODIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SODIUM_ION_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION","description":"Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."} {"geneset":"GO_NEGATIVE_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity."} {"geneset":"GO_HISTONE_DEUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_DEUBIQUITINATION","description":"The modification of histones by removal of ubiquitin groups."} {"geneset":"GO_GLUCOSAMINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOSAMINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines)."} {"geneset":"GO_ORGANIC_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ACID_TRANSPORT","description":"The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_FOREBRAIN_REGIONALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOREBRAIN_REGIONALIZATION","description":"The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops."} {"geneset":"GO_FOREBRAIN_GENERATION_OF_NEURONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOREBRAIN_GENERATION_OF_NEURONS","description":"The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons."} {"geneset":"GO_CALCIUM_DEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_DEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES","description":"The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction."} {"geneset":"GO_PANCREAS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PANCREAS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes."} {"geneset":"GO_LEUKOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_CHEMOTAXIS","description":"The movement of a leukocyte in response to an external stimulus."} {"geneset":"GO_GLUCOSE_6_PHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOSE_6_PHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6."} {"geneset":"GO_MITOCHONDRIAL_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_TRANSMEMBRANE_TRANSPORT","description":"The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion."} {"geneset":"GO_NUCLEAR_PORE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_PORE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore."} {"geneset":"GO_CELLULAR_RESPONSE_TO_NITRIC_OXIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_NITRIC_OXIDE","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus."} {"geneset":"GO_INTRA_S_DNA_DAMAGE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRA_S_DNA_DAMAGE_CHECKPOINT","description":"A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression."} {"geneset":"GO_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY","description":"Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."} {"geneset":"GO_HISTONE_H3_K9_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H3_K9_MODIFICATION","description":"The modification of histone H3 at a lysine in position 9 of the histone."} {"geneset":"GO_RESPONSE_TO_INTERFERON_ALPHA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INTERFERON_ALPHA","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSLATIONAL_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSLATIONAL_INITIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation."} {"geneset":"GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway."} {"geneset":"GO_CARDIAC_CONDUCTION_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CONDUCTION_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat."} {"geneset":"GO_REGULATION_OF_GLOMERULAR_FILTRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLOMERULAR_FILTRATION","description":"Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule."} {"geneset":"GO_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."} {"geneset":"GO_CYTOCHROME_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOCHROME_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions."} {"geneset":"GO_RESPONSE_TO_METAL_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_METAL_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus."} {"geneset":"GO_CELL_SUBSTRATE_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_SUBSTRATE_ADHESION","description":"The attachment of a cell to the underlying substrate via adhesion molecules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction."} {"geneset":"GO_ENDOCARDIAL_CUSHION_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCARDIAL_CUSHION_FORMATION","description":"The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."} {"geneset":"GO_REGULATION_OF_NUCLEAR_CELL_CYCLE_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEAR_CELL_CYCLE_DNA_REPLICATION","description":"Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."} {"geneset":"GO_ORGANIC_HYDROXY_COMPOUND_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_HYDROXY_COMPOUND_TRANSPORT","description":"The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom."} {"geneset":"GO_MITOCHONDRIAL_CALCIUM_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_CALCIUM_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings."} {"geneset":"GO_REPLACEMENT_OSSIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REPLACEMENT_OSSIFICATION","description":"Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation."} {"geneset":"GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS","description":"Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton."} {"geneset":"GO_WOUND_HEALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WOUND_HEALING","description":"The series of events that restore integrity to a damaged tissue, following an injury."} {"geneset":"GO_MITOTIC_CELL_CYCLE_ARREST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_CELL_CYCLE_ARREST","description":"The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M)."} {"geneset":"GO_HEXOSE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEXOSE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule."} {"geneset":"GO_GLUTAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid."} {"geneset":"GO_RESPONSE_TO_NERVE_GROWTH_FACTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_NERVE_GROWTH_FACTOR","description":"A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TELOMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TELOMERASE_ACTIVITY","description":"Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."} {"geneset":"GO_RNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_PROCESSING","description":"Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules."} {"geneset":"GO_REGULATION_OF_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE","description":"Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response."} {"geneset":"GO_POSITIVE_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids."} {"geneset":"GO_SYNAPTIC_VESICLE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_VESICLE_CYCLE","description":"A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters."} {"geneset":"GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS","description":"The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 from a cell."} {"geneset":"GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION","description":"Any process that activates or increases the frequency, rate or extent of leukocyte proliferation."} {"geneset":"GO_PSEUDOURIDINE_SYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PSEUDOURIDINE_SYNTHESIS","description":"The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs."} {"geneset":"GO_CELLULAR_PROTEIN_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_PROTEIN_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell."} {"geneset":"GO_DEFENSE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEFENSE_RESPONSE","description":"Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack."} {"geneset":"GO_POLY_A_MRNA_EXPORT_FROM_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLY_A_MRNA_EXPORT_FROM_NUCLEUS","description":"The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm."} {"geneset":"GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process."} {"geneset":"GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds."} {"geneset":"GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_4","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_4","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus."} {"geneset":"GO_PORPHYRIN_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PORPHYRIN_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group."} {"geneset":"GO_SPERM_CAPACITATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERM_CAPACITATION","description":"A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium."} {"geneset":"GO_POSITIVE_REGULATION_OF_TELOMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TELOMERASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production."} {"geneset":"GO_CELLULAR_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell."} {"geneset":"GO_RESPONSE_TO_METHYLMERCURY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_METHYLMERCURY","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus."} {"geneset":"GO_REGULATION_OF_CENTRIOLE_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CENTRIOLE_REPLICATION","description":"Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole."} {"geneset":"GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS","description":"Any process that activates or increases frequency, rate or extent of chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level."} {"geneset":"GO_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of an acute inflammatory response."} {"geneset":"GO_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_PRODUCTION","description":"The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."} {"geneset":"GO_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells."} {"geneset":"GO_FOREBRAIN_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOREBRAIN_CELL_MIGRATION","description":"The orderly movement of a cell from one site to another at least one of which is located in the forebrain."} {"geneset":"GO_DEMETHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEMETHYLATION","description":"The process of removing one or more methyl groups from a molecule."} {"geneset":"GO_CELL_MOTILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MOTILITY","description":"Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another."} {"geneset":"GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION","description":"Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."} {"geneset":"GO_DECIDUALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DECIDUALIZATION","description":"The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta."} {"geneset":"GO_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION","description":"Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body."} {"geneset":"GO_CERAMIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CERAMIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ORGAN_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ORGAN_GROWTH","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus."} {"geneset":"GO_ORGANOPHOSPHATE_ESTER_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANOPHOSPHATE_ESTER_TRANSPORT","description":"The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds."} {"geneset":"GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins."} {"geneset":"GO_HISTONE_MONOUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_MONOUBIQUITINATION","description":"The modification of histones by addition of a single ubiquitin group."} {"geneset":"GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION","description":"Any process that modulates the frequency, rate or extent of cell cycle G2/M phase transition."} {"geneset":"GO_EMBRYONIC_VISCEROCRANIUM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_VISCEROCRANIUM_MORPHOGENESIS","description":"The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones."} {"geneset":"GO_SOMATIC_CELL_DNA_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMATIC_CELL_DNA_RECOMBINATION","description":"Recombination occurring within or between DNA molecules in somatic cells."} {"geneset":"GO_PIGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIGMENTATION","description":"The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY","description":"Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSLATIONAL_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSLATIONAL_INITIATION","description":"Any process that activates or increases the frequency, rate or extent of translational initiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_AGING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_AGING","description":"Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan."} {"geneset":"GO_B_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_B_CELL_MEDIATED_IMMUNITY","description":"Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells."} {"geneset":"GO_AORTA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AORTA_DEVELOPMENT","description":"The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body."} {"geneset":"GO_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT","description":"The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta."} {"geneset":"GO_ASYMMETRIC_CELL_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASYMMETRIC_CELL_DIVISION","description":"The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity."} {"geneset":"GO_SPECIFICATION_OF_SYMMETRY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPECIFICATION_OF_SYMMETRY","description":"The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM","description":"A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum."} {"geneset":"GO_BILE_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BILE_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile."} {"geneset":"GO_NEGATIVE_REGULATION_OF_COAGULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_COAGULATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation."} {"geneset":"GO_HISTONE_EXCHANGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_EXCHANGE","description":"The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits."} {"geneset":"GO_LIPID_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of lipid within an organism or cell."} {"geneset":"GO_CELLULAR_RESPIRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPIRATION","description":"The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)."} {"geneset":"GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DAMAGE_RECOGNITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DAMAGE_RECOGNITION","description":"The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix."} {"geneset":"GO_REGULATION_OF_ENDOTHELIAL_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOTHELIAL_CELL_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of endothelial cell development."} {"geneset":"GO_B_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_B_CELL_DIFFERENTIATION","description":"The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity."} {"geneset":"GO_NEURAL_PRECURSOR_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURAL_PRECURSOR_CELL_PROLIFERATION","description":"The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell."} {"geneset":"GO_NUCLEAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_TRANSPORT","description":"The directed movement of substances into, out of, or within the nucleus."} {"geneset":"GO_PEPTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION","description":"Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules."} {"geneset":"GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of epithelial cell differentiation."} {"geneset":"GO_ENDOTHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOTHELIAL_CELL_MIGRATION","description":"The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."} {"geneset":"GO_ORGANIC_HYDROXY_COMPOUND_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_HYDROXY_COMPOUND_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound."} {"geneset":"GO_GLYCEROLIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCEROLIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis."} {"geneset":"GO_PEPTIDYL_AMINO_ACID_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_AMINO_ACID_MODIFICATION","description":"The alteration of an amino acid residue in a peptide."} {"geneset":"GO_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECRETION","description":"The controlled release of a substance by a cell or a tissue."} {"geneset":"GO_REGULATION_OF_SEQUESTERING_OF_TRIGLYCERIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SEQUESTERING_OF_TRIGLYCERIDE","description":"Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."} {"geneset":"GO_NEGATIVE_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization."} {"geneset":"GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_VASODILATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VASODILATION","description":"Any process that activates or increases the frequency, rate or extent of vasodilation."} {"geneset":"GO_HOMOCYSTEINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOMOCYSTEINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HISTONE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HISTONE_MODIFICATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of a histone."} {"geneset":"GO_COFACTOR_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COFACTOR_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein."} {"geneset":"GO_PYRIMIDINE_CONTAINING_COMPOUND_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_CONTAINING_COMPOUND_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_BINDING","description":"Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."} {"geneset":"GO_VENTRAL_SPINAL_CORD_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRAL_SPINAL_CORD_DEVELOPMENT","description":"The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output."} {"geneset":"GO_REGULATION_OF_CIRCADIAN_RHYTHM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CIRCADIAN_RHYTHM","description":"Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours."} {"geneset":"GO_ANION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANION_TRANSPORT","description":"The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_ADHESION","description":"The attachment of one cell to another cell via adhesion molecules."} {"geneset":"GO_MORPHOGENESIS_OF_AN_ENDOTHELIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MORPHOGENESIS_OF_AN_ENDOTHELIUM","description":"The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."} {"geneset":"GO_GUANOSINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GUANOSINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving guanosine-containing compounds (guanosines)."} {"geneset":"GO_POSITIVE_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL","description":"Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria."} {"geneset":"GO_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides."} {"geneset":"GO_CHONDROITIN_SULFATE_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHONDROITIN_SULFATE_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."} {"geneset":"GO_GLANDULAR_EPITHELIAL_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLANDULAR_EPITHELIAL_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland."} {"geneset":"GO_RESPONSE_TO_MAGNESIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MAGNESIUM_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ATP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ATP","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus."} {"geneset":"GO_CHOLESTEROL_EFFLUX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHOLESTEROL_EFFLUX","description":"The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."} {"geneset":"GO_PROTEIN_OLIGOMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_OLIGOMERIZATION","description":"The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."} {"geneset":"GO_BETA_CATENIN_DESTRUCTION_COMPLEX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_CATENIN_DESTRUCTION_COMPLEX_DISASSEMBLY","description":"The disaggregation of a beta-catenin destruction complex into its constituent components."} {"geneset":"GO_INNER_DYNEIN_ARM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNER_DYNEIN_ARM_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes."} {"geneset":"GO_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of epithelial cell proliferation."} {"geneset":"GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY","description":"The formation or destruction of chromatin structures."} {"geneset":"GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY","description":"Any process that modulates the activity of the enzyme nitric-oxide synthase."} {"geneset":"GO_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway."} {"geneset":"GO_LEFT_RIGHT_PATTERN_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEFT_RIGHT_PATTERN_FORMATION","description":"The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."} {"geneset":"GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."} {"geneset":"GO_RESPONSE_TO_XENOBIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_XENOBIOTIC_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms."} {"geneset":"GO_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION","description":"Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."} {"geneset":"GO_EMBRYONIC_DIGESTIVE_TRACT_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_DIGESTIVE_TRACT_MORPHOGENESIS","description":"The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed."} {"geneset":"GO_PLACENTA_BLOOD_VESSEL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLACENTA_BLOOD_VESSEL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_GUANYLATE_CYCLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GUANYLATE_CYCLASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity."} {"geneset":"GO_MELANIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MELANIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS","description":"Any process that activates, maintains or increases the rate of a response to an external stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION","description":"Any process that activates or increases the frequency, rate or extent of cell cycle G2/M phase transition."} {"geneset":"GO_REGULATION_OF_REMOVAL_OF_SUPEROXIDE_RADICALS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_REMOVAL_OF_SUPEROXIDE_RADICALS","description":"Any process that modulates the frequency, rate or extent of removal of superoxide radicals."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STEM_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STEM_CELL_PROLIFERATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation."} {"geneset":"GO_AGING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AGING","description":"A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700)."} {"geneset":"GO_REGULATION_OF_VACUOLAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VACUOLAR_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of vacuolar transport."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ELECTRICAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ELECTRICAL_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus."} {"geneset":"GO_REGULATION_OF_OXIDATIVE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OXIDATIVE_PHOSPHORYLATION","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway."} {"geneset":"GO_REGULATION_OF_BONE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BONE_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of bone development."} {"geneset":"GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY","description":"Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity."} {"geneset":"GO_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY","description":"Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity."} {"geneset":"GO_REGULATION_OF_CHOLESTEROL_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHOLESTEROL_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol."} {"geneset":"GO_POLYSACCHARIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYSACCHARIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."} {"geneset":"GO_NEGATIVE_REGULATION_OF_AUTOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_AUTOPHAGY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."} {"geneset":"GO_INNER_CELL_MASS_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNER_CELL_MASS_CELL_PROLIFERATION","description":"The proliferation of cells in the inner cell mass."} {"geneset":"GO_POSITIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME","description":"Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism."} {"geneset":"GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION","description":"Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION","description":"Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication."} {"geneset":"GO_STARTLE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STARTLE_RESPONSE","description":"An action or movement due to the application of a sudden unexpected stimulus."} {"geneset":"GO_MOTOR_NEURON_AXON_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MOTOR_NEURON_AXON_GUIDANCE","description":"The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues."} {"geneset":"GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs)."} {"geneset":"GO_PYRIMIDINE_RIBONUCLEOSIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_RIBONUCLEOSIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."} {"geneset":"GO_RESPONSE_TO_ENDOGENOUS_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ENDOGENOUS_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism."} {"geneset":"GO_HYPOTHALAMUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYPOTHALAMUS_DEVELOPMENT","description":"The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state."} {"geneset":"GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells."} {"geneset":"GO_POSITIVE_REGULATION_OF_MEIOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MEIOTIC_CELL_CYCLE","description":"Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle."} {"geneset":"GO_LATERAL_MESODERM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LATERAL_MESODERM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_MATRIX_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_MATRIX_ADHESION","description":"Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix."} {"geneset":"GO_EMBRYO_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYO_DEVELOPMENT","description":"The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant."} {"geneset":"GO_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION","description":"Any process that modulates the frequency, rate or extent of striated muscle contraction."} {"geneset":"GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of leukocyte differentiation."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."} {"geneset":"GO_WATER_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WATER_TRANSPORT","description":"The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ESTABLISHMENT_OF_CELL_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_CELL_POLARITY","description":"The specification and formation of anisotropic intracellular organization or cell growth patterns."} {"geneset":"GO_BIOTIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BIOTIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions."} {"geneset":"GO_STEM_CELL_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEM_CELL_DIVISION","description":"The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types."} {"geneset":"GO_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen."} {"geneset":"GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme."} {"geneset":"GO_DIGESTIVE_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIGESTIVE_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."} {"geneset":"GO_POSITIVE_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS","description":"Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."} {"geneset":"GO_DNA_CONFORMATION_CHANGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_CONFORMATION_CHANGE","description":"A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule."} {"geneset":"GO_DETECTION_OF_MECHANICAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_MECHANICAL_STIMULUS","description":"The series of events by which a mechanical stimulus is received and converted into a molecular signal."} {"geneset":"GO_SEXUAL_REPRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEXUAL_REPRODUCTION","description":"A reproduction process that creates a new organism by combining the genetic material of two organisms. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two different individuals (parents) join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny."} {"geneset":"GO_EPIDERMAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPIDERMAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis."} {"geneset":"GO_SYNAPTONEMAL_COMPLEX_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTONEMAL_COMPLEX_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis."} {"geneset":"GO_BASE_EXCISION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASE_EXCISION_REPAIR","description":"In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase."} {"geneset":"GO_CELLULAR_CARBOHYDRATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_CARBOHYDRATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response."} {"geneset":"GO_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides."} {"geneset":"GO_TAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TAXIS","description":"The directed movement of a motile cell or organism in response to an external stimulus."} {"geneset":"GO_CITRULLINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CITRULLINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."} {"geneset":"GO_NEGATIVE_REGULATION_OF_AXON_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_AXON_GUIDANCE","description":"Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance."} {"geneset":"GO_ORGAN_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGAN_FORMATION","description":"The process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL","description":"Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION","description":"Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte."} {"geneset":"GO_RESPONSE_TO_GLUCAGON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_GLUCAGON","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TISSUE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TISSUE_REMODELING","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling."} {"geneset":"GO_MEMBRANE_TUBULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_TUBULATION","description":"A modification in a plasma membrane resulting in formation of a tubular invagination."} {"geneset":"GO_EMBRYONIC_PLACENTA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_PLACENTA_DEVELOPMENT","description":"The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."} {"geneset":"GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule."} {"geneset":"GO_ANATOMICAL_STRUCTURE_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANATOMICAL_STRUCTURE_MATURATION","description":"A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state."} {"geneset":"GO_REGULATION_OF_AMYLOID_PRECURSOR_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_AMYLOID_PRECURSOR_PROTEIN_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process."} {"geneset":"GO_CELLULAR_EXTRAVASATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_EXTRAVASATION","description":"The migration of a leukocyte from the blood vessels into the surrounding tissue."} {"geneset":"GO_REGULATION_OF_TELOMERE_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TELOMERE_MAINTENANCE","description":"Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."} {"geneset":"GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS","description":"Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."} {"geneset":"GO_NEGATIVE_REGULATION_OF_WOUND_HEALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_WOUND_HEALING","description":"Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury."} {"geneset":"GO_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of immunoglobulin production."} {"geneset":"GO_FATTY_ACYL_COA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACYL_COA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS","description":"Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."} {"geneset":"GO_GPI_ANCHOR_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GPI_ANCHOR_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain."} {"geneset":"GO_POSITIVE_REGULATION_OF_HISTONE_DEACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HISTONE_DEACETYLATION","description":"Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones."} {"geneset":"GO_BLOOD_COAGULATION_FIBRIN_CLOT_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLOOD_COAGULATION_FIBRIN_CLOT_FORMATION","description":"A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events."} {"geneset":"GO_POSITIVE_REGULATION_OF_INSULIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INSULIN_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the regulated release of insulin."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_AMYLOID_PRECURSOR_PROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMYLOID_PRECURSOR_PROTEIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease."} {"geneset":"GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS","description":"The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis."} {"geneset":"GO_CHEMICAL_HOMEOSTASIS_WITHIN_A_TISSUE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMICAL_HOMEOSTASIS_WITHIN_A_TISSUE","description":"Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue."} {"geneset":"GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of myeloid cell differentiation."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS","description":"Any process that modulates the frequency, rate or extent of a response to an external stimulus."} {"geneset":"GO_REGULATION_OF_RNA_POLYMERASE_II_TRANSCRIPTIONAL_PREINITIATION_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RNA_POLYMERASE_II_TRANSCRIPTIONAL_PREINITIATION_COMPLEX_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."} {"geneset":"GO_RETROGRADE_PROTEIN_TRANSPORT_ER_TO_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETROGRADE_PROTEIN_TRANSPORT_ER_TO_CYTOSOL","description":"The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon."} {"geneset":"GO_EPITHELIAL_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_CELL_ADHESION","description":"The attachment of an epithelial cell to another epithelial cell via adhesion molecules."} {"geneset":"GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."} {"geneset":"GO_POLYAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYAMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups."} {"geneset":"GO_POSITIVE_REGULATION_OF_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MUSCLE_CONTRACTION","description":"Any process that activates or increases the frequency, rate or extent of muscle contraction."} {"geneset":"GO_NEGATIVE_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."} {"geneset":"GO_PTERIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PTERIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid."} {"geneset":"GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION","description":"The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS","description":"Any process that activates or increases the frequency, rate or extent of protein localization to nucleus."} {"geneset":"GO_POSITIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity."} {"geneset":"GO_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma."} {"geneset":"GO_PROXIMAL_DISTAL_PATTERN_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROXIMAL_DISTAL_PATTERN_FORMATION","description":"The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)."} {"geneset":"GO_STRIATED_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRIATED_MUSCLE_CONTRACTION","description":"A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ANION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ANION_TRANSPORT","description":"Any process that stops, prevents or reduces the frequency, rate or extent of anion transport."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation."} {"geneset":"GO_ECTODERM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ECTODERM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation."} {"geneset":"GO_HYALURONAN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYALURONAN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine."} {"geneset":"GO_LEUKOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_MIGRATION","description":"The movement of a leukocyte within or between different tissues and organs of the body."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT","description":"Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells."} {"geneset":"GO_MEIOSIS_I","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEIOSIS_I","description":"The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei."} {"geneset":"GO_SENSORY_PERCEPTION_OF_PAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_PERCEPTION_OF_PAIN","description":"The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC","description":"Any epigenetic process that stops, prevents or reduces the rate of gene expression."} {"geneset":"GO_ALDITOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALDITOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."} {"geneset":"GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_UBIQUINOL_TO_CYTOCHROME_C","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_UBIQUINOL_TO_CYTOCHROME_C","description":"The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III."} {"geneset":"GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE","description":"Any process that modulates the size of an anatomical structure."} {"geneset":"GO_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development."} {"geneset":"GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION","description":"Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."} {"geneset":"GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY","description":"Any process that activates or increases the activity of an enzyme."} {"geneset":"GO_POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","description":"Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator."} {"geneset":"GO_PEPTIDYL_LYSINE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_LYSINE_MODIFICATION","description":"The modification of peptidyl-lysine."} {"geneset":"GO_METHYLATION_DEPENDENT_CHROMATIN_SILENCING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METHYLATION_DEPENDENT_CHROMATIN_SILENCING","description":"Repression of transcription by methylation of DNA, leading to the formation of heterochromatin."} {"geneset":"GO_REGULATION_OF_LIPOPROTEIN_LIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPOPROTEIN_LIPASE_ACTIVITY","description":"Any process that modulates the activity of the enzyme lipoprotein lipase."} {"geneset":"GO_HORMONE_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HORMONE_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals mediated by the detection of a hormone."} {"geneset":"GO_ANDROGEN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANDROGEN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_BINDING","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding."} {"geneset":"GO_POSITIVE_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation."} {"geneset":"GO_AXONEMAL_DYNEIN_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXONEMAL_DYNEIN_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion."} {"geneset":"GO_REGULATION_OF_LIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPID_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids."} {"geneset":"GO_HEMIDESMOSOME_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEMIDESMOSOME_ASSEMBLY","description":"Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina."} {"geneset":"GO_MAST_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAST_CELL_ACTIVATION","description":"The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors."} {"geneset":"GO_RESPONSE_TO_EXTERNAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_EXTERNAL_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus."} {"geneset":"GO_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION","description":"A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope."} {"geneset":"GO_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of adenylate cyclase activity."} {"geneset":"GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of leukocyte differentiation."} {"geneset":"GO_MITOCHONDRIAL_MEMBRANE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_MEMBRANE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEUTROPHIL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEUTROPHIL_MIGRATION","description":"Any process that activates or increases the frequency, rate or extent of neutrophil migration."} {"geneset":"GO_INTRA_GOLGI_VESICLE_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRA_GOLGI_VESICLE_MEDIATED_TRANSPORT","description":"The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network)."} {"geneset":"GO_REGULATION_OF_SPINDLE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SPINDLE_CHECKPOINT","description":"Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle."} {"geneset":"GO_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION","description":"Any process that activates or increases the frequency, rate or extent of striated muscle contraction."} {"geneset":"GO_ANATOMICAL_STRUCTURE_REGRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANATOMICAL_STRUCTURE_REGRESSION","description":"The developmental process in which an anatomical stucture is destroyed as a part of its normal progression."} {"geneset":"GO_CEREBRAL_CORTEX_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBRAL_CORTEX_NEURON_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex."} {"geneset":"GO_OVARIAN_FOLLICLE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OVARIAN_FOLLICLE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure."} {"geneset":"GO_REGULATION_OF_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","description":"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."} {"geneset":"GO_REGULATION_OF_MYOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MYOBLAST_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."} {"geneset":"GO_GLUCAN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCAN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues."} {"geneset":"GO_CARDIAC_ATRIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_ATRIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS","description":"Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."} {"geneset":"GO_FATTY_ACID_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell."} {"geneset":"GO_NUCLEOTIDE_SUGAR_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_SUGAR_METABOLIC_PROCESS","description":"The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."} {"geneset":"GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS","description":"The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released."} {"geneset":"GO_REGULATION_OF_PLATELET_AGGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PLATELET_AGGREGATION","description":"Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION","description":"Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION","description":"Any process that increases the frequency, rate or extent of cardiac muscle contraction."} {"geneset":"GO_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING","description":"Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading."} {"geneset":"GO_NEPHRIC_DUCT_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEPHRIC_DUCT_DEVELOPMENT","description":"The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney."} {"geneset":"GO_POST_GOLGI_VESICLE_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POST_GOLGI_VESICLE_MEDIATED_TRANSPORT","description":"The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles."} {"geneset":"GO_ERROR_FREE_TRANSLESION_SYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERROR_FREE_TRANSLESION_SYNTHESIS","description":"The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level."} {"geneset":"GO_EYE_PHOTORECEPTOR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EYE_PHOTORECEPTOR_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms."} {"geneset":"GO_RESPONSE_TO_TESTOSTERONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_TESTOSTERONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus."} {"geneset":"GO_CENTRIOLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTRIOLE_ASSEMBLY","description":"A cellular process that results in the assembly of one or more centrioles."} {"geneset":"GO_REGULATION_OF_HEMOPOIESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEMOPOIESIS","description":"Any process that modulates the frequency, rate or extent of hemopoiesis."} {"geneset":"GO_ATRIAL_SEPTUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATRIAL_SEPTUM_DEVELOPMENT","description":"The progression of the atrial septum over time, from its initial formation to the mature structure."} {"geneset":"GO_DETECTION_OF_TEMPERATURE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_TEMPERATURE_STIMULUS","description":"The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal."} {"geneset":"GO_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ION_TRANSMEMBRANE_TRANSPORT","description":"A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."} {"geneset":"GO_ENAMEL_MINERALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENAMEL_MINERALIZATION","description":"The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel."} {"geneset":"GO_POSITIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING","description":"Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling."} {"geneset":"GO_NEURAL_CREST_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURAL_CREST_CELL_MIGRATION","description":"The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo."} {"geneset":"GO_SPINAL_CORD_MOTOR_NEURON_CELL_FATE_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINAL_CORD_MOTOR_NEURON_CELL_FATE_SPECIFICATION","description":"The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway."} {"geneset":"GO_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of glycoprotein metabolic process."} {"geneset":"GO_INTRACELLULAR_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_SIGNAL_TRANSDUCTION","description":"The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell."} {"geneset":"GO_REGULATION_OF_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BEHAVIOR","description":"Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."} {"geneset":"GO_PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_GLYCOLIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOLIPID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)."} {"geneset":"GO_SYNAPTIC_VESICLE_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_VESICLE_ENDOCYTOSIS","description":"Clathrin-mediated endocytosis of presynaptic membrane that recycles synaptic vesicle membrane and its components following synaptic vesicle exocytosis. This process starts with coating of the membrane with adaptor proteins and clathrin prior to invagination and ends when uncoating has finished."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY","description":"Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity."} {"geneset":"GO_POSITIVE_REGULATION_OF_HEART_RATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HEART_RATE","description":"Any process that activates or increases the frequency or rate of heart contraction."} {"geneset":"GO_PALATE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PALATE_DEVELOPMENT","description":"The biological process whose specific outcome is the progression of the palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The palate is the partition that separates the nasal and oral cavities."} {"geneset":"GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor."} {"geneset":"GO_PATTERNING_OF_BLOOD_VESSELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PATTERNING_OF_BLOOD_VESSELS","description":"The process that regulates the coordinated growth and sprouting of blood vessels giving rise to the organized vascular system."} {"geneset":"GO_REGULATION_OF_HOMEOSTATIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HOMEOSTATIC_PROCESS","description":"Any process that modulates the frequency, rate, or extent of a homeostatic process."} {"geneset":"GO_FATTY_ACID_BETA_OXIDATION_USING_ACYL_COA_OXIDASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_BETA_OXIDATION_USING_ACYL_COA_OXIDASE","description":"A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."} {"geneset":"GO_POSITIVE_REGULATION_OF_VASOCONSTRICTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VASOCONSTRICTION","description":"Any process that activates or increases the frequency, rate or extent of vasoconstriction."} {"geneset":"GO_GOLGI_TO_PLASMA_MEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_TO_PLASMA_MEMBRANE_TRANSPORT","description":"The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis."} {"geneset":"GO_PROTEIN_TARGETING_TO_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TARGETING_TO_MEMBRANE","description":"The process of directing proteins towards a membrane, usually using signals contained within the protein."} {"geneset":"GO_MITOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_CELL_CYCLE","description":"Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent."} {"geneset":"GO_REGULATION_OF_FEEDING_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FEEDING_BEHAVIOR","description":"Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food."} {"geneset":"GO_REGULATION_OF_THYMOCYTE_AGGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_THYMOCYTE_AGGREGATION","description":"Any process that modulates the frequency, rate or extent of thymocyte aggregation."} {"geneset":"GO_PROTEIN_COMPLEX_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_COMPLEX_BIOGENESIS","description":"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex."} {"geneset":"GO_REGULATION_OF_MULTICELLULAR_ORGANISM_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MULTICELLULAR_ORGANISM_GROWTH","description":"Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size."} {"geneset":"GO_REGULATION_OF_KIDNEY_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_KIDNEY_DEVELOPMENT","description":"Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_MACROMOLECULAR_COMPLEX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMOLECULAR_COMPLEX_DISASSEMBLY","description":"The disaggregation of a macromolecular complex into its constituent components."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS","description":"Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component."} {"geneset":"GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY","description":"Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane."} {"geneset":"GO_COMPLEMENT_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COMPLEMENT_ACTIVATION","description":"Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway."} {"geneset":"GO_REGULATION_OF_CATECHOLAMINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CATECHOLAMINE_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of catecholamines."} {"geneset":"GO_BONE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_DEVELOPMENT","description":"The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."} {"geneset":"GO_DERMATAN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DERMATAN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."} {"geneset":"GO_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."} {"geneset":"GO_REGULATION_OF_AMINE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_AMINE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_SMOOTH_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMOOTH_MUSCLE_TISSUE_DEVELOPMENT","description":"The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity."} {"geneset":"GO_NCRNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NCRNA_PROCESSING","description":"Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_THYMOCYTE_AGGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THYMOCYTE_AGGREGATION","description":"The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules."} {"geneset":"GO_LEYDIG_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEYDIG_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis."} {"geneset":"GO_AMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."} {"geneset":"GO_DNA_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_MODIFICATION","description":"The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_MEMBRANE","description":"A process in which a protein is transported to, or maintained in, a specific location in a membrane."} {"geneset":"GO_RNA_SURVEILLANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_SURVEILLANCE","description":"The set of processes involved in identifying and degrading defective or aberrant RNAs."} {"geneset":"GO_MITOTIC_SPINDLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_SPINDLE_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis."} {"geneset":"GO_REGULATION_OF_GRANULOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GRANULOCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of granulocyte differentiation."} {"geneset":"GO_RESPONSE_TO_ALKALOID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ALKALOID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active."} {"geneset":"GO_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."} {"geneset":"GO_MORPHOGENESIS_OF_AN_EPITHELIAL_FOLD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MORPHOGENESIS_OF_AN_EPITHELIAL_FOLD","description":"The morphogenetic process in which an epithelial sheet bends along a linear axis."} {"geneset":"GO_AUTOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AUTOPHAGY","description":"The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation."} {"geneset":"GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."} {"geneset":"GO_REGULATION_OF_ACTIN_FILAMENT_LENGTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIN_FILAMENT_LENGTH","description":"Any process that controls the length of actin filaments in a cell."} {"geneset":"GO_REGULATION_OF_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSPORTER_ACTIVITY","description":"Any process that modulates the activity of a transporter."} {"geneset":"GO_EATING_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EATING_BEHAVIOR","description":"The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue."} {"geneset":"GO_GLUTATHIONE_DERIVATIVE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTATHIONE_DERIVATIVE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glutathione derivative."} {"geneset":"GO_CELL_JUNCTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_JUNCTION_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix."} {"geneset":"GO_FOLIC_ACID_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOLIC_ACID_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of folic acid and its derivatives."} {"geneset":"GO_EMBRYONIC_HEART_TUBE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_HEART_TUBE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field."} {"geneset":"GO_SPHINGOID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPHINGOID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."} {"geneset":"GO_PROTEIN_DESTABILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DESTABILIZATION","description":"Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_FOOD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_FOOD","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus."} {"geneset":"GO_L_AMINO_ACID_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_L_AMINO_ACID_IMPORT","description":"The directed movement of L-enantiomer amino acids into a cell or organelle."} {"geneset":"GO_EAR_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EAR_DEVELOPMENT","description":"The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_MATRIX_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_MATRIX_ADHESION","description":"Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix."} {"geneset":"GO_REGULATION_OF_MACROPHAGE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MACROPHAGE_CHEMOTAXIS","description":"Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."} {"geneset":"GO_LAGGING_STRAND_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAGGING_STRAND_ELONGATION","description":"The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork."} {"geneset":"GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION","description":"Any process that activates or increases the rate or extent of smooth muscle cell proliferation."} {"geneset":"GO_MEMBRANE_BUDDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_BUDDING","description":"The evagination of a membrane, resulting in formation of a vesicle."} {"geneset":"GO_REGULATION_OF_SYNAPTIC_PLASTICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPTIC_PLASTICITY","description":"A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."} {"geneset":"GO_LONG_TERM_SYNAPTIC_DEPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LONG_TERM_SYNAPTIC_DEPRESSION","description":"A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse."} {"geneset":"GO_GLYCOSYLCERAMIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSYLCERAMIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."} {"geneset":"GO_CELLULAR_RESPONSE_TO_RETINOIC_ACID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_RETINOIC_ACID","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus."} {"geneset":"GO_NCRNA_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NCRNA_TRANSCRIPTION","description":"The transcription of non (protein) coding RNA from a DNA template."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-1 beta production."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway."} {"geneset":"GO_LIPOXYGENASE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOXYGENASE_PATHWAY","description":"The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process."} {"geneset":"GO_VESICLE_DOCKING_INVOLVED_IN_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_DOCKING_INVOLVED_IN_EXOCYTOSIS","description":"The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis."} {"geneset":"GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION","description":"The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."} {"geneset":"GO_ARTERY_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARTERY_MORPHOGENESIS","description":"The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS","description":"Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication."} {"geneset":"GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION","description":"Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."} {"geneset":"GO_POSITIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of regulated secretory pathway."} {"geneset":"GO_SPROUTING_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPROUTING_ANGIOGENESIS","description":"The extension of new blood vessels from existing capillaries into avascular tissues resulting from the proliferation of blood vessel endothelial cells."} {"geneset":"GO_LYMPHOCYTE_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_ACTIVATION","description":"A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor."} {"geneset":"GO_METALLO_SULFUR_CLUSTER_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METALLO_SULFUR_CLUSTER_ASSEMBLY","description":"The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity."} {"geneset":"GO_SPLICEOSOMAL_TRI_SNRNP_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPLICEOSOMAL_TRI_SNRNP_COMPLEX_ASSEMBLY","description":"The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex."} {"geneset":"GO_REGULATION_OF_T_CELL_TOLERANCE_INDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_TOLERANCE_INDUCTION","description":"Any process that modulates the frequency, rate, or extent of T cell tolerance induction."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS","description":"Any process that activates or increases the frequency, rate or extent of response to oxidative stress."} {"geneset":"GO_PROTEIN_TRIMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TRIMERIZATION","description":"The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits."} {"geneset":"GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION","description":"Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine."} {"geneset":"GO_PROTEOGLYCAN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEOGLYCAN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."} {"geneset":"GO_NITROGEN_COMPOUND_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NITROGEN_COMPOUND_TRANSPORT","description":"The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_DOPAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOPAMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."} {"geneset":"GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM","description":"Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism."} {"geneset":"GO_POSITIVE_REGULATION_OF_GLYCOGEN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GLYCOGEN_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen."} {"geneset":"GO_LEUKOCYTE_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_PROLIFERATION","description":"The expansion of a leukocyte population by cell division."} {"geneset":"GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION","description":"Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization."} {"geneset":"GO_L_ASCORBIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_L_ASCORBIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species."} {"geneset":"GO_CEREBELLAR_GRANULAR_LAYER_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBELLAR_GRANULAR_LAYER_DEVELOPMENT","description":"The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."} {"geneset":"GO_REGULATION_OF_GENE_EXPRESSION_BY_GENETIC_IMPRINTING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GENE_EXPRESSION_BY_GENETIC_IMPRINTING","description":"Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself."} {"geneset":"GO_ADHERENS_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADHERENS_JUNCTION_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments."} {"geneset":"GO_SECRETORY_GRANULE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECRETORY_GRANULE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion."} {"geneset":"GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-12 production."} {"geneset":"GO_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the occurrence or rate of T cell death by apoptotic process."} {"geneset":"GO_VESICLE_FUSION_TO_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_FUSION_TO_PLASMA_MEMBRANE","description":"Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space."} {"geneset":"GO_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","description":"The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure."} {"geneset":"GO_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HISTONE_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HISTONE_METHYLATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones."} {"geneset":"GO_REGULATION_OF_GLIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLIAL_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of glial cell proliferation."} {"geneset":"GO_IN_UTERO_EMBRYONIC_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IN_UTERO_EMBRYONIC_DEVELOPMENT","description":"The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BLOOD_CIRCULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BLOOD_CIRCULATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation."} {"geneset":"GO_ER_NUCLEUS_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ER_NUCLEUS_SIGNALING_PATHWAY","description":"Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation."} {"geneset":"GO_ETHANOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ETHANOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."} {"geneset":"GO_DICARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DICARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups."} {"geneset":"GO_PROTEIN_HETEROTRIMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HETEROTRIMERIZATION","description":"The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical."} {"geneset":"GO_VESICLE_CYTOSKELETAL_TRAFFICKING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_CYTOSKELETAL_TRAFFICKING","description":"The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS","description":"Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus."} {"geneset":"GO_EPITHELIAL_CILIUM_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CILIUM_MOVEMENT","description":"The directed, self-propelled movement of a cilium of an epithelial cell. This movement is usually coordinated between many epithelial cells, and serves to move fluid."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MEIOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MEIOTIC_CELL_CYCLE","description":"Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle."} {"geneset":"GO_MESENCHYMAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESENCHYMAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process."} {"geneset":"GO_SHORT_CHAIN_FATTY_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SHORT_CHAIN_FATTY_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving fatty acids with a chain length of less than C6."} {"geneset":"GO_ATRIAL_SEPTUM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATRIAL_SEPTUM_MORPHOGENESIS","description":"The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another."} {"geneset":"GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION","description":"Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction."} {"geneset":"GO_CELLULAR_RESPONSE_TO_GROWTH_HORMONE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_GROWTH_HORMONE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2."} {"geneset":"GO_RNA_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_MODIFICATION","description":"The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically."} {"geneset":"GO_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS","description":"The cellular component assembly that is part of the initial shaping of the component during its developmental progression."} {"geneset":"GO_ORGANELLE_FISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_FISSION","description":"The creation of two or more organelles by division of one organelle."} {"geneset":"GO_EMBRYONIC_FORELIMB_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_FORELIMB_MORPHOGENESIS","description":"The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human."} {"geneset":"GO_REGULATION_OF_FIBROBLAST_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FIBROBLAST_APOPTOTIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of fibroblast apoptotic process."} {"geneset":"GO_NOSE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NOSE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)."} {"geneset":"GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT","description":"The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER","description":"Any process that modulates the frequency, rate or extent of transcription from an RNA ploymerase III promoter."} {"geneset":"GO_MUSCLE_STRUCTURE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_STRUCTURE_DEVELOPMENT","description":"The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS","description":"Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."} {"geneset":"GO_RESPONSE_TO_INCREASED_OXYGEN_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INCREASED_OXYGEN_LEVELS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen."} {"geneset":"GO_REGULATION_OF_CHROMATIN_SILENCING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHROMATIN_SILENCING","description":"Any process that affects the rate, extent or location of chromatin silencing."} {"geneset":"GO_MACROMOLECULAR_COMPLEX_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMOLECULAR_COMPLEX_REMODELING","description":"The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex."} {"geneset":"GO_RIBOSOMAL_LARGE_SUBUNIT_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOMAL_LARGE_SUBUNIT_ASSEMBLY","description":"The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit."} {"geneset":"GO_MAINTENANCE_OF_LOCATION_IN_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAINTENANCE_OF_LOCATION_IN_CELL","description":"Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere."} {"geneset":"GO_CEREBELLAR_CORTEX_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBELLAR_CORTEX_DEVELOPMENT","description":"The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."} {"geneset":"GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION","description":"Any process that modulates the frequency, rate or extent of microtubule polymerization."} {"geneset":"GO_REGULATION_OF_MESODERM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MESODERM_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of mesoderm development."} {"geneset":"GO_T_HELPER_1_TYPE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_HELPER_1_TYPE_IMMUNE_RESPONSE","description":"An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin."} {"geneset":"GO_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate, or extent of a type 2 immune response."} {"geneset":"GO_PLASMA_LIPOPROTEIN_PARTICLE_CLEARANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLASMA_LIPOPROTEIN_PARTICLE_CLEARANCE","description":"The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."} {"geneset":"GO_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen."} {"geneset":"GO_DNA_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_CATABOLIC_PROCESS","description":"The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one."} {"geneset":"GO_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway."} {"geneset":"GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus."} {"geneset":"GO_RESPONSE_TO_PROSTAGLANDIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PROSTAGLANDIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus."} {"geneset":"GO_CELL_FATE_COMMITMENT_INVOLVED_IN_FORMATION_OF_PRIMARY_GERM_LAYER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_FATE_COMMITMENT_INVOLVED_IN_FORMATION_OF_PRIMARY_GERM_LAYER","description":"The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation."} {"geneset":"GO_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_REPAIR","description":"The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway."} {"geneset":"GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."} {"geneset":"GO_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands."} {"geneset":"GO_PROTEIN_HETEROTETRAMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HETEROTETRAMERIZATION","description":"The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HEART_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HEART_CONTRACTION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction."} {"geneset":"GO_SUBSTRATE_INDEPENDENT_TELENCEPHALIC_TANGENTIAL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUBSTRATE_INDEPENDENT_TELENCEPHALIC_TANGENTIAL_MIGRATION","description":"The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact."} {"geneset":"GO_SULFUR_COMPOUND_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFUR_COMPOUND_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."} {"geneset":"GO_CHLORIDE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHLORIDE_TRANSPORT","description":"The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_MICROTUBULE_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_DEPOLYMERIZATION","description":"The removal of tubulin heterodimers from one or both ends of a microtubule."} {"geneset":"GO_PROTEIN_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_POLYMERIZATION","description":"The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein."} {"geneset":"GO_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids."} {"geneset":"GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE","description":"A cascade of processes induced by the detection of DNA damage within a cell."} {"geneset":"GO_COBALAMIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COBALAMIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE","description":"The process that reduces the force with which blood travels through the systemic arterial circulatory system."} {"geneset":"GO_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_CONTRACTION","description":"A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis."} {"geneset":"GO_TELOMERE_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERE_LOCALIZATION","description":"Any process in which a telomere is transported to, and/or maintained in, a specific location."} {"geneset":"GO_TRANSITION_METAL_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSITION_METAL_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver."} {"geneset":"GO_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of adherens junction organization."} {"geneset":"GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY","description":"Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_PYRIMIDINE_NUCLEOTIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOTIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_PROTEIN_KINASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG)."} {"geneset":"GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_VIRUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_VIRUS","description":"Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism."} {"geneset":"GO_REGULATION_OF_RECEPTOR_INTERNALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RECEPTOR_INTERNALIZATION","description":"Any process that modulates the frequency, rate or extent of receptor internalization."} {"geneset":"GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_CENTROMERIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_CENTROMERIC_REGION","description":"Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome."} {"geneset":"GO_RESPONSE_TO_BACTERIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_BACTERIUM","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium."} {"geneset":"GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION","description":"Any process that modulates the frequency, rate, or extent of antigen processing and presentation."} {"geneset":"GO_VASOCONSTRICTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASOCONSTRICTION","description":"A decrease in the diameter of blood vessels, especially arteries, usually causing an increase in blood pressure."} {"geneset":"GO_REGULATION_OF_MITOCHONDRIAL_TRANSLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOCHONDRIAL_TRANSLATION","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion."} {"geneset":"GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION","description":"Any process that activates or increases the frequency, rate, or extent of leukocyte migration."} {"geneset":"GO_CALCIUM_ION_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ION_IMPORT","description":"The directed movement of calcium ions into a cell or organelle."} {"geneset":"GO_CELL_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MATURATION","description":"A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state."} {"geneset":"GO_BEHAVIORAL_RESPONSE_TO_PAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BEHAVIORAL_RESPONSE_TO_PAIN","description":"Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli."} {"geneset":"GO_REGULATION_OF_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SECRETION","description":"Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."} {"geneset":"GO_CELLULAR_RESPONSE_TO_TOXIC_SUBSTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_TOXIC_SUBSTANCE","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus."} {"geneset":"GO_MODULATION_OF_TRANSCRIPTION_IN_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODULATION_OF_TRANSCRIPTION_IN_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION","description":"Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction."} {"geneset":"GO_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APOPTOTIC_SIGNALING_PATHWAY","description":"A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered."} {"geneset":"GO_NEURAL_NUCLEUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURAL_NUCLEUS_DEVELOPMENT","description":"The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma."} {"geneset":"GO_LYMPHOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_MEDIATED_IMMUNITY","description":"Any process involved in the carrying out of an immune response by a lymphocyte."} {"geneset":"GO_REGULATION_OF_HEART_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEART_MORPHOGENESIS","description":"Any process that modulates the frequency, rate or extent of heart morphogenesis."} {"geneset":"GO_S_ADENOSYLMETHIONINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_S_ADENOSYLMETHIONINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."} {"geneset":"GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region."} {"geneset":"GO_HIPPOCAMPUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HIPPOCAMPUS_DEVELOPMENT","description":"The progression of the hippocampus over time from its initial formation until its mature state."} {"geneset":"GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_SURFACE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_SURFACE","description":"Any process that modulates the frequency, rate or extent of protein localization to the cell surface."} {"geneset":"GO_RIBONUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."} {"geneset":"GO_PRIMARY_AMINO_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRIMARY_AMINO_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving primary amino compound."} {"geneset":"GO_POSITIVE_REGULATION_OF_TELOMERE_CAPPING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TELOMERE_CAPPING","description":"Any process that activates or increases the frequency, rate or extent of telomere capping."} {"geneset":"GO_NEGATIVE_REGULATION_OF_AMINE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_AMINE_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_CHROMOSOME_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHROMOSOME_SEGREGATION","description":"Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."} {"geneset":"GO_POSITIVE_REGULATION_OF_INSULIN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INSULIN_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that increases the frequency, rate or extent of insulin receptor signaling."} {"geneset":"GO_PONS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PONS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."} {"geneset":"GO_PROTEIN_K11_LINKED_UBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_K11_LINKED_UBIQUITINATION","description":"A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains."} {"geneset":"GO_DETECTION_OF_CHEMICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION_OF_TASTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_CHEMICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION_OF_TASTE","description":"The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal."} {"geneset":"GO_REGULATION_OF_MESENCHYMAL_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MESENCHYMAL_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process."} {"geneset":"GO_RESPONSE_TO_INACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INACTIVITY","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus."} {"geneset":"GO_SPHINGOLIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPHINGOLIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."} {"geneset":"GO_RESPONSE_TO_PAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PAIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli."} {"geneset":"GO_PROTEIN_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_ACETYLATION","description":"The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic"} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."} {"geneset":"GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_IMPORT","description":"Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."} {"geneset":"GO_CELLULAR_HORMONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_HORMONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells."} {"geneset":"GO_PTERIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PTERIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid."} {"geneset":"GO_BONE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_REMODELING","description":"The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis."} {"geneset":"GO_EMBRYONIC_CAMERA_TYPE_EYE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_CAMERA_TYPE_EYE_MORPHOGENESIS","description":"The process in which the anatomical structures of the eye are generated and organized during embryonic development."} {"geneset":"GO_FORMATION_OF_TRANSLATION_PREINITIATION_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FORMATION_OF_TRANSLATION_PREINITIATION_COMPLEX","description":"The joining of the small ribosomal subunit, ternary complex, and mRNA."} {"geneset":"GO_CHEMOKINE_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMOKINE_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interferon-beta production."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration."} {"geneset":"GO_REGULATION_OF_PROTEIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_SECRETION","description":"Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell."} {"geneset":"GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION","description":"Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."} {"geneset":"GO_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION","description":"Any process that modulates the frequency, rate or extent of natural killer cell activation."} {"geneset":"GO_RESPONSE_TO_INSULIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INSULIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms."} {"geneset":"GO_POSITIVE_REGULATION_OF_FILOPODIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_FILOPODIUM_ASSEMBLY","description":"Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."} {"geneset":"GO_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."} {"geneset":"GO_POSITIVE_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING","description":"Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling."} {"geneset":"GO_REGULATION_OF_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances."} {"geneset":"GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines."} {"geneset":"GO_ROSTROCAUDAL_NEURAL_TUBE_PATTERNING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ROSTROCAUDAL_NEURAL_TUBE_PATTERNING","description":"The process in which the neural tube is divided into specific regions along the rostrocaudal axis."} {"geneset":"GO_B_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_B_CELL_ACTIVATION","description":"The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."} {"geneset":"GO_CELL_DEATH_IN_RESPONSE_TO_OXIDATIVE_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DEATH_IN_RESPONSE_TO_OXIDATIVE_STRESS","description":"Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus."} {"geneset":"GO_REGULATION_OF_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEURON_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of neuron differentiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon."} {"geneset":"GO_REGULATION_OF_FIBRINOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FIBRINOLYSIS","description":"Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB."} {"geneset":"GO_PROTEIN_POLYUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_POLYUBIQUITINATION","description":"Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain."} {"geneset":"GO_RIBONUCLEOPROTEIN_COMPLEX_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOPROTEIN_COMPLEX_LOCALIZATION","description":"Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell."} {"geneset":"GO_REGULATION_OF_MRNA_3_END_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MRNA_3_END_PROCESSING","description":"Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule."} {"geneset":"GO_REGULATION_OF_PEPTIDE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PEPTIDE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ION_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ATP_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATP_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator."} {"geneset":"GO_CANONICAL_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CANONICAL_WNT_SIGNALING_PATHWAY","description":"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes."} {"geneset":"GO_ACUTE_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACUTE_INFLAMMATORY_RESPONSE","description":"Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response."} {"geneset":"GO_NUCLEOBASE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOBASE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine."} {"geneset":"GO_HUMORAL_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HUMORAL_IMMUNE_RESPONSE","description":"An immune response mediated through a body fluid."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_10_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_10_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production."} {"geneset":"GO_PHAGOSOME_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOSOME_MATURATION","description":"A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome."} {"geneset":"GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HYPOXIA","description":"Any process that modulates the frequency, rate or extent of cellular response to hypoxia."} {"geneset":"GO_REGULATION_OF_FEMALE_GONAD_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FEMALE_GONAD_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of female gonad development."} {"geneset":"GO_REGULATION_OF_THYMOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_THYMOCYTE_APOPTOTIC_PROCESS","description":"Any process that modulates the occurrence or rate of thymocyte death by apoptotic process."} {"geneset":"GO_CHROMATIN_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_MODIFICATION","description":"The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure."} {"geneset":"GO_MYELOID_LEUKOCYTE_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_LEUKOCYTE_ACTIVATION","description":"A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand."} {"geneset":"GO_REACTIVE_NITROGEN_SPECIES_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REACTIVE_NITROGEN_SPECIES_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a reactive nitrogen species."} {"geneset":"GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION","description":"The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_DIVISION","description":"Any process that activates or increases the frequency, rate or extent of cell division."} {"geneset":"GO_EYELID_DEVELOPMENT_IN_CAMERA_TYPE_EYE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EYELID_DEVELOPMENT_IN_CAMERA_TYPE_EYE","description":"The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye."} {"geneset":"GO_PIGMENT_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIGMENT_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin."} {"geneset":"GO_ERBB_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERBB_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_EMBRYONIC_ORGAN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_ORGAN_MORPHOGENESIS","description":"Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."} {"geneset":"GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT","description":"The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction."} {"geneset":"GO_CYTOSOLIC_CALCIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSOLIC_CALCIUM_ION_TRANSPORT","description":"The directed movement of calcium ions (Ca2+) into, out of or within the cytosol."} {"geneset":"GO_REGULATION_OF_SPINDLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SPINDLE_ORGANIZATION","description":"Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle."} {"geneset":"GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances."} {"geneset":"GO_PHOSPHOLIPID_SCRAMBLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_SCRAMBLING","description":"The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE)."} {"geneset":"GO_GLIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLIOGENESIS","description":"The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia."} {"geneset":"GO_PEPTIDYL_THREONINE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_THREONINE_MODIFICATION","description":"The modification of peptidyl-threonine."} {"geneset":"GO_MITOCHONDRIAL_FISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_FISSION","description":"The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."} {"geneset":"GO_MATURATION_OF_5_8S_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATURATION_OF_5_8S_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_","description":"Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SPROUTING_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SPROUTING_ANGIOGENESIS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis."} {"geneset":"GO_POLYOL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYOL_TRANSPORT","description":"The directed movement of polyols, any polyhydric alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_CALCIUM_ION_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_CALCIUM_ION_SIGNALING","description":"Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction."} {"geneset":"GO_ANTIGEN_PROCESSING_AND_PRESENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_PROCESSING_AND_PRESENTATION","description":"The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."} {"geneset":"GO_CELLULAR_AMINO_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_AMINO_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents."} {"geneset":"GO_TELENCEPHALON_GLIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELENCEPHALON_GLIAL_CELL_MIGRATION","description":"The orderly movement of glial cells through the telencephalon."} {"geneset":"GO_MAINTENANCE_OF_LOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAINTENANCE_OF_LOCATION","description":"Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere."} {"geneset":"GO_NEPHRON_EPITHELIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEPHRON_EPITHELIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RECEPTOR_ACTIVITY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity."} {"geneset":"GO_KERATINOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KERATINOCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte."} {"geneset":"GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme."} {"geneset":"GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration."} {"geneset":"GO_POSITIVE_REGULATION_OF_SYNAPSE_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SYNAPSE_MATURATION","description":"Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state."} {"geneset":"GO_PERIPHERAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERIPHERAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system."} {"geneset":"GO_CELL_REDOX_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_REDOX_HOMEOSTASIS","description":"Any process that maintains the redox environment of a cell or compartment within a cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION","description":"Any process that activates or increases the frequency, rate or extent of smooth muscle contraction."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GLIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GLIAL_CELL_PROLIFERATION","description":"Any process that stops or decreases the rate or extent of glial cell proliferation."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."} {"geneset":"GO_REGULATION_OF_STEROID_HORMONE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STEROID_HORMONE_SECRETION","description":"Any process that modulates the frequency, rate or extent of steroid hormone secretion."} {"geneset":"GO_RESPONSE_TO_KETONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_KETONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B."} {"geneset":"GO_LYMPHANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHANGIOGENESIS","description":"Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels."} {"geneset":"GO_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL","description":"Any process that modulates the potential difference across a post-synaptic membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway."} {"geneset":"GO_SENSORY_PERCEPTION_OF_TASTE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_PERCEPTION_OF_TASTE","description":"The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process."} {"geneset":"GO_FEAR_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FEAR_RESPONSE","description":"The response of an organism to a perceived external threat."} {"geneset":"GO_REGULATION_OF_CLATHRIN_MEDIATED_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CLATHRIN_MEDIATED_ENDOCYTOSIS","description":"Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis."} {"geneset":"GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION","description":"Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."} {"geneset":"GO_LABYRINTHINE_LAYER_BLOOD_VESSEL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LABYRINTHINE_LAYER_BLOOD_VESSEL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply."} {"geneset":"GO_NEURON_NEURON_SYNAPTIC_TRANSMISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_NEURON_SYNAPTIC_TRANSMISSION","description":"The process of communication from a neuron to another neuron across a synapse."} {"geneset":"GO_INNER_MITOCHONDRIAL_MEMBRANE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNER_MITOCHONDRIAL_MEMBRANE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane."} {"geneset":"GO_CILIUM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIUM_MORPHOGENESIS","description":"A process that is carried out at the cellular level and in which the structure of a cilium is organized."} {"geneset":"GO_ENERGY_COUPLED_PROTON_TRANSPORT_DOWN_ELECTROCHEMICAL_GRADIENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENERGY_COUPLED_PROTON_TRANSPORT_DOWN_ELECTROCHEMICAL_GRADIENT","description":"The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP."} {"geneset":"GO_POSITIVE_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY","description":"Any process that activates or increases the activity of a phosphoprotein phosphatase."} {"geneset":"GO_CELLULAR_MODIFIED_AMINO_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_MODIFIED_AMINO_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_VACUOLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_VACUOLE","description":"A process in which a protein is transported to, or maintained at, a location in a vacuole."} {"geneset":"GO_METANEPHRIC_RENAL_VESICLE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METANEPHRIC_RENAL_VESICLE_MORPHOGENESIS","description":"The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction."} {"geneset":"GO_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus."} {"geneset":"GO_REGULATION_OF_ORGAN_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ORGAN_GROWTH","description":"Any process that modulates the frequency, rate or extent of growth of an organ of an organism."} {"geneset":"GO_REGULATION_OF_SYNAPSE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPSE_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NEUROTRANSMITTER_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NEUROTRANSMITTER_SECRETION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_GROWTH","description":"Any process that activates or increases the frequency, rate, extent or direction of cell growth."} {"geneset":"GO_NEGATIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY","description":"Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered."} {"geneset":"GO_EMBRYONIC_DIGESTIVE_TRACT_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_DIGESTIVE_TRACT_DEVELOPMENT","description":"The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus."} {"geneset":"GO_PROTEIN_O_LINKED_MANNOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_O_LINKED_MANNOSYLATION","description":"The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage."} {"geneset":"GO_GUANOSINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GUANOSINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines)."} {"geneset":"GO_BONE_MINERALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_MINERALIZATION","description":"The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue."} {"geneset":"GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY","description":"Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ORGANIC_SUBSTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ORGANIC_SUBSTANCE","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus."} {"geneset":"GO_OVULATION_CYCLE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OVULATION_CYCLE_PROCESS","description":"A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_ADHESION","description":"Any process that activates or increases the frequency, rate or extent of cell adhesion."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CHROMATIN","description":"Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin."} {"geneset":"GO_PROTEIN_O_LINKED_FUCOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_O_LINKED_FUCOSYLATION","description":"The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage."} {"geneset":"GO_CEREBRAL_CORTEX_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBRAL_CORTEX_DEVELOPMENT","description":"The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon."} {"geneset":"GO_ENDOCRINE_PANCREAS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCRINE_PANCREAS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_8_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_8_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-8 production."} {"geneset":"GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS","description":"The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis."} {"geneset":"GO_ORGANIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage."} {"geneset":"GO_REGULATION_OF_EXCRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXCRETION","description":"Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity."} {"geneset":"GO_AROMATIC_AMINO_ACID_FAMILY_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AROMATIC_AMINO_ACID_FAMILY_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."} {"geneset":"GO_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING","description":"Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process."} {"geneset":"GO_REGULATION_OF_ENDOCRINE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOCRINE_PROCESS","description":"Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system."} {"geneset":"GO_RESPONSE_TO_INSECTICIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INSECTICIDE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects."} {"geneset":"GO_REGULATION_OF_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING","description":"Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length."} {"geneset":"GO_QUATERNARY_AMMONIUM_GROUP_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_QUATERNARY_AMMONIUM_GROUP_TRANSPORT","description":"The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups."} {"geneset":"GO_EXIT_FROM_MITOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXIT_FROM_MITOSIS","description":"The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."} {"geneset":"GO_REGULATION_OF_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM","description":"Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association."} {"geneset":"GO_RESPONSE_TO_GROWTH_HORMONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_GROWTH_HORMONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth."} {"geneset":"GO_PROTEIN_DEMANNOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DEMANNOSYLATION","description":"The removal of one or more mannose residues from a mannosylated protein."} {"geneset":"GO_G1_DNA_DAMAGE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G1_DNA_DAMAGE_CHECKPOINT","description":"A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase in the cell cycle in response to DNA damage."} {"geneset":"GO_POSITIVE_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription from RNA polymerase II promoter."} {"geneset":"GO_RESPONSE_TO_OXYGEN_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_OXYGEN_LEVELS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen."} {"geneset":"GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS","description":"Any process that activates or increases the frequency, rate, or extent of an immune system process."} {"geneset":"GO_PHOTOTRANSDUCTION_VISIBLE_LIGHT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTOTRANSDUCTION_VISIBLE_LIGHT","description":"The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm."} {"geneset":"GO_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION","description":"Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION","description":"Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome."} {"geneset":"GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity."} {"geneset":"GO_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS","description":"Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."} {"geneset":"GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY","description":"Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity."} {"geneset":"GO_POSITIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT","description":"Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."} {"geneset":"GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus."} {"geneset":"GO_N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein."} {"geneset":"GO_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II."} {"geneset":"GO_OXIDATIVE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDATIVE_PHOSPHORYLATION","description":"The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."} {"geneset":"GO_APOPTOTIC_NUCLEAR_CHANGES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APOPTOTIC_NUCLEAR_CHANGES","description":"Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis."} {"geneset":"GO_REGULATION_OF_RAC_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RAC_PROTEIN_SIGNAL_TRANSDUCTION","description":"Any process that modulates the frequency, rate or extent of Rac protein signal transduction."} {"geneset":"GO_CELLULAR_AMIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_AMIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells."} {"geneset":"GO_PARENTAL_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PARENTAL_BEHAVIOR","description":"A reproductive behavior in which a parent cares for and rears offspring."} {"geneset":"GO_REGULATION_OF_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_BINDING","description":"Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."} {"geneset":"GO_IMMUNOGLOBULIN_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNOGLOBULIN_PRODUCTION","description":"The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."} {"geneset":"GO_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta."} {"geneset":"GO_TISSUE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TISSUE_MIGRATION","description":"The process in which the population of cells that make up a tissue undergo directed movement."} {"geneset":"GO_ONE_CARBON_COMPOUND_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ONE_CARBON_COMPOUND_TRANSPORT","description":"The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_LEFT_RIGHT_AXIS_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEFT_RIGHT_AXIS_SPECIFICATION","description":"The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes)."} {"geneset":"GO_RESPONSE_TO_ISCHEMIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ISCHEMIA","description":"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply."} {"geneset":"GO_ENSHEATHMENT_OF_NEURONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENSHEATHMENT_OF_NEURONS","description":"The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment."} {"geneset":"GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS","description":"Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."} {"geneset":"GO_CHROMATIN_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_DISASSEMBLY","description":"The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA."} {"geneset":"GO_PLATELET_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_MORPHOGENESIS","description":"Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation."} {"geneset":"GO_DENDRITE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITE_MORPHOGENESIS","description":"The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell."} {"geneset":"GO_RESPONSE_TO_AMPHETAMINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_AMPHETAMINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine."} {"geneset":"GO_RESPONSE_TO_CAMP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_CAMP","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus."} {"geneset":"GO_MYOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOBLAST_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers."} {"geneset":"GO_POSITIVE_REGULATION_OF_ACTIN_NUCLEATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ACTIN_NUCLEATION","description":"Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament."} {"geneset":"GO_REGULATION_OF_MEGAKARYOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEGAKARYOCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of megakaryocyte differentiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis."} {"geneset":"GO_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of muscle cell differentiation."} {"geneset":"GO_INNATE_IMMUNE_RESPONSE_IN_MUCOSA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNATE_IMMUNE_RESPONSE_IN_MUCOSA","description":"Any process of the innate immune response that takes place in the mucosal tissues."} {"geneset":"GO_REGULATION_OF_CHEMOKINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHEMOKINE_SECRETION","description":"Any process that modulates the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell."} {"geneset":"GO_RESPONSE_TO_STEROL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_STEROL","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus."} {"geneset":"GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."} {"geneset":"GO_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS","description":"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis."} {"geneset":"GO_TRABECULA_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRABECULA_MORPHOGENESIS","description":"The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."} {"geneset":"GO_PHOTORECEPTOR_CELL_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_CELL_MAINTENANCE","description":"Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light."} {"geneset":"GO_REGULATION_OF_CALCIUM_ION_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CALCIUM_ION_IMPORT","description":"Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."} {"geneset":"GO_HEPARAN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEPARAN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups."} {"geneset":"GO_INTESTINAL_EPITHELIAL_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTESTINAL_EPITHELIAL_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure."} {"geneset":"GO_CELLULAR_RESPONSE_TO_GLUCAGON_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_GLUCAGON_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus."} {"geneset":"GO_REGULATION_OF_METAL_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_METAL_ION_TRANSPORT","description":"Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response."} {"geneset":"GO_MODIFICATION_BY_SYMBIONT_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODIFICATION_BY_SYMBIONT_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY","description":"The process in which a symbiont organism effects a change in the structure or processes of its host organism."} {"geneset":"GO_SISTER_CHROMATID_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SISTER_CHROMATID_SEGREGATION","description":"The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets."} {"geneset":"GO_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS","description":"Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."} {"geneset":"GO_PHASIC_SMOOTH_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHASIC_SMOOTH_MUSCLE_CONTRACTION","description":"A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations."} {"geneset":"GO_AXON_ENSHEATHMENT_IN_CENTRAL_NERVOUS_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXON_ENSHEATHMENT_IN_CENTRAL_NERVOUS_SYSTEM","description":"The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction."} {"geneset":"GO_MONOSACCHARIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOSACCHARIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms."} {"geneset":"GO_ORGANELLE_MEMBRANE_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_MEMBRANE_FUSION","description":"The joining of two lipid bilayers to form a single organelle membrane."} {"geneset":"GO_REGULATION_OF_ERK1_AND_ERK2_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ERK1_AND_ERK2_CASCADE","description":"Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."} {"geneset":"GO_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY","description":"Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity."} {"geneset":"GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of carbohydrate derivative."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY","description":"Any process that activates or increases the frequency, rate or extent of cell junction assembly."} {"geneset":"GO_NONRIBOSOMAL_PEPTIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NONRIBOSOMAL_PEPTIDE_BIOSYNTHETIC_PROCESS","description":"The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione."} {"geneset":"GO_HEART_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_MORPHOGENESIS","description":"The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."} {"geneset":"GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION","description":"A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DENDRITE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DENDRITE_DEVELOPMENT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development."} {"geneset":"GO_REGULATION_OF_HORMONE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HORMONE_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell."} {"geneset":"GO_REGULATION_OF_CALCIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CALCIUM_ION_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_SENSORY_PERCEPTION_OF_LIGHT_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_PERCEPTION_OF_LIGHT_STIMULUS","description":"The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."} {"geneset":"GO_TERPENOID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TERPENOID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups."} {"geneset":"GO_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PROLIFERATION","description":"The multiplication or reproduction of cells, resulting in the expansion of a cell population."} {"geneset":"GO_REGULATION_OF_LIPID_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPID_KINASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid."} {"geneset":"GO_POSITIVE_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of osteoclast differentiation."} {"geneset":"GO_LYSOSOME_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSOSOME_LOCALIZATION","description":"Any process in which a lysosome is transported to, and/or maintained in, a specific location."} {"geneset":"GO_VITAMIN_D_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VITAMIN_D_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."} {"geneset":"GO_REGULATION_OF_FIBROBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FIBROBLAST_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells."} {"geneset":"GO_CELL_AGGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_AGGREGATION","description":"The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation."} {"geneset":"GO_RESPONSE_TO_HORMONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_HORMONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus."} {"geneset":"GO_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION","description":"Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."} {"geneset":"GO_REGULATION_OF_HEXOKINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEXOKINASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of hexokinase activity."} {"geneset":"GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND","description":"Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."} {"geneset":"GO_CATECHOLAMINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATECHOLAMINE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."} {"geneset":"GO_POSITIVE_REGULATION_OF_MUSCLE_HYPERTROPHY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MUSCLE_HYPERTROPHY","description":"Any process that activates or increases the frequency, rate or extent of muscle hypertrophy."} {"geneset":"GO_EMBRYONIC_PATTERN_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_PATTERN_SPECIFICATION","description":"The process that results in the patterns of cell differentiation that will arise in an embryo."} {"geneset":"GO_RESPONSE_TO_PROTOZOAN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PROTOZOAN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan."} {"geneset":"GO_MULTIVESICULAR_BODY_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTIVESICULAR_BODY_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm."} {"geneset":"GO_REGULATION_OF_CELL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_GROWTH","description":"Any process that modulates the frequency, rate, extent or direction of cell growth."} {"geneset":"GO_CENTROSOME_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTROSOME_CYCLE","description":"The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle."} {"geneset":"GO_RESPONSE_TO_FIBROBLAST_GROWTH_FACTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_FIBROBLAST_GROWTH_FACTOR","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus."} {"geneset":"GO_PROTEIN_CARBOXYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_CARBOXYLATION","description":"The addition of a carboxy group to a protein amino acid."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING","description":"Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening."} {"geneset":"GO_DEOXYRIBONUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEOXYRIBONUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."} {"geneset":"GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage."} {"geneset":"GO_POSITIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of extracellular matrix organization."} {"geneset":"GO_LEARNING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEARNING","description":"Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience."} {"geneset":"GO_CILIUM_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIUM_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."} {"geneset":"GO_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_FOOD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_FOOD","description":"Any process that modulates the frequency, rate or extent of a response to a food stimulus."} {"geneset":"GO_CHONDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHONDROCYTE_DIFFERENTIATION","description":"The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage."} {"geneset":"GO_REGULATION_OF_CELLULAR_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_LOCALIZATION","description":"Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell."} {"geneset":"GO_ADRENERGIC_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADRENERGIC_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands."} {"geneset":"GO_OVULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OVULATION","description":"The release of a mature ovum/oocyte from an ovary."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TOR_SIGNALING","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling."} {"geneset":"GO_SUBSTANTIA_NIGRA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUBSTANTIA_NIGRA_DEVELOPMENT","description":"The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)."} {"geneset":"GO_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_","description":"Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."} {"geneset":"GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_INVOLVED_IN_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_INVOLVED_IN_INFLAMMATORY_RESPONSE","description":"The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels."} {"geneset":"GO_PREPULSE_INHIBITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PREPULSE_INHIBITION","description":"The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse."} {"geneset":"GO_REGULATION_OF_EARLY_ENDOSOME_TO_LATE_ENDOSOME_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EARLY_ENDOSOME_TO_LATE_ENDOSOME_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of early endosome to late endosome transport."} {"geneset":"GO_MIDDLE_EAR_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MIDDLE_EAR_MORPHOGENESIS","description":"The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)."} {"geneset":"GO_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."} {"geneset":"GO_JNK_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_JNK_CASCADE","description":"An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell."} {"geneset":"GO_RESPONSE_TO_SALT_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_SALT_STRESS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."} {"geneset":"GO_ENDODERMAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDODERMAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo."} {"geneset":"GO_PROTEIN_KINASE_B_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_B_SIGNALING","description":"A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound."} {"geneset":"GO_SOMITOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMITOGENESIS","description":"The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo."} {"geneset":"GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of multicellular organismal development."} {"geneset":"GO_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT","description":"Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_ACTIVATION_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_ACTIVATION_CASCADE","description":"Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade."} {"geneset":"GO_TRICARBOXYLIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRICARBOXYLIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-)."} {"geneset":"GO_REGULATION_OF_TRIGLYCERIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRIGLYCERIDE_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus."} {"geneset":"GO_HEMATOPOIETIC_STEM_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEMATOPOIETIC_STEM_CELL_PROLIFERATION","description":"The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization."} {"geneset":"GO_RENAL_TUBULE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_TUBULE_DEVELOPMENT","description":"The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis."} {"geneset":"GO_CARDIAC_VENTRICLE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_VENTRICLE_MORPHOGENESIS","description":"The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart."} {"geneset":"GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I","description":"The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules."} {"geneset":"GO_REGULATION_OF_THE_FORCE_OF_HEART_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_THE_FORCE_OF_HEART_CONTRACTION","description":"Any process that modulates the extent of heart contraction, changing the force with which blood is propelled."} {"geneset":"GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process."} {"geneset":"GO_MACROMOLECULAR_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMOLECULAR_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of macromolecules to form a complex."} {"geneset":"GO_PROTEIN_STABILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_STABILIZATION","description":"Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion."} {"geneset":"GO_ASPARTATE_FAMILY_AMINO_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASPARTATE_FAMILY_AMINO_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_SECRETION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LIPASE_ACTIVITY","description":"Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."} {"geneset":"GO_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS","description":"Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."} {"geneset":"GO_MATURATION_OF_LSU_RRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATURATION_OF_LSU_RRNA","description":"Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule."} {"geneset":"GO_RNA_SPLICING_VIA_ENDONUCLEOLYTIC_CLEAVAGE_AND_LIGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_SPLICING_VIA_ENDONUCLEOLYTIC_CLEAVAGE_AND_LIGATION","description":"Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."} {"geneset":"GO_REGULATION_OF_SYNAPSE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPSE_ORGANIZATION","description":"Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."} {"geneset":"GO_MUSCLE_ADAPTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_ADAPTATION","description":"A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."} {"geneset":"GO_INTERFERON_GAMMA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERFERON_GAMMA_PRODUCTION","description":"The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon."} {"geneset":"GO_OPTIC_NERVE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OPTIC_NERVE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."} {"geneset":"GO_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG)."} {"geneset":"GO_REGULATION_OF_KERATINOCYTE_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_KERATINOCYTE_PROLIFERATION","description":"Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."} {"geneset":"GO_GAS_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GAS_TRANSPORT","description":"The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."} {"geneset":"GO_REGULATION_OF_MAST_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MAST_CELL_ACTIVATION","description":"Any process that modulates the frequency, rate, or extent of mast cell activation."} {"geneset":"GO_MIDBRAIN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MIDBRAIN_DEVELOPMENT","description":"The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)."} {"geneset":"GO_NEURON_FATE_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_FATE_SPECIFICATION","description":"The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."} {"geneset":"GO_ORGANIC_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage."} {"geneset":"GO_REPRODUCTIVE_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REPRODUCTIVE_BEHAVIOR","description":"The specific behavior of an organism that is associated with reproduction."} {"geneset":"GO_ESTABLISHMENT_OF_TISSUE_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_TISSUE_POLARITY","description":"Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates."} {"geneset":"GO_REGULATION_OF_NEURON_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEURON_APOPTOTIC_PROCESS","description":"Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons."} {"geneset":"GO_CELL_SEPARATION_AFTER_CYTOKINESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_SEPARATION_AFTER_CYTOKINESIS","description":"The process of physically separating progeny cells after cytokinesis; this may involve enzymatic digestion of septum or cell wall components."} {"geneset":"GO_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS","description":"Any process that modulates the frequency, rate or extent of glucose import in response to insulin stimulus."} {"geneset":"GO_AMIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group."} {"geneset":"GO_POSITIVE_REGULATION_OF_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EXOCYTOSIS","description":"Any process that activates or increases the frequency, rate or extent of exocytosis."} {"geneset":"GO_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET","description":"The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells."} {"geneset":"GO_CHEMOSENSORY_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMOSENSORY_BEHAVIOR","description":"Behavior that is dependent upon the sensation of chemicals."} {"geneset":"GO_PROTEIN_KINASE_C_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_C_SIGNALING","description":"A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."} {"geneset":"GO_GLUCOSE_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOSE_IMPORT","description":"The directed movement of the hexose monosaccharide glucose into a cell or organelle."} {"geneset":"GO_SISTER_CHROMATID_COHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SISTER_CHROMATID_COHESION","description":"The cell cycle process in which the sister chromatids of a replicated chromosome are associated with each other."} {"geneset":"GO_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING","description":"Any process that modulates I-kappaB kinase/NF-kappaB signaling."} {"geneset":"GO_REGULATION_OF_PROTEIN_KINASE_A_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_KINASE_A_SIGNALING","description":"Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound."} {"geneset":"GO_HEPATOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEPATOCYTE_APOPTOTIC_PROCESS","description":"Any apoptotic process in a hepatocyte, the main structural component of the liver."} {"geneset":"GO_TETRAHYDROFOLATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TETRAHYDROFOLATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group."} {"geneset":"GO_ORGAN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGAN_MORPHOGENESIS","description":"Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."} {"geneset":"GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs."} {"geneset":"GO_REGULATION_OF_NECROTIC_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NECROTIC_CELL_DEATH","description":"Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents."} {"geneset":"GO_CELLULAR_RESPONSE_TO_CAMP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_CAMP","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME","description":"Any process in which a protein is transported to, or maintained at, a specific location on a chromosome."} {"geneset":"GO_POSTSYNAPTIC_MEMBRANE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSTSYNAPTIC_MEMBRANE_ORGANIZATION","description":"A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)."} {"geneset":"GO_CARNITINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARNITINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."} {"geneset":"GO_CYTOPLASMIC_TRANSLATIONAL_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_TRANSLATIONAL_INITIATION","description":"The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA."} {"geneset":"GO_COMPLEMENT_ACTIVATION_ALTERNATIVE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COMPLEMENT_ACTIVATION_ALTERNATIVE_PATHWAY","description":"Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes."} {"geneset":"GO_CARDIAC_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_MUSCLE_CELL_DIFFERENTIATION","description":"The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."} {"geneset":"GO_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar."} {"geneset":"GO_CILIUM_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIUM_MOVEMENT","description":"The directed, self-propelled movement of a cilium."} {"geneset":"GO_BRANCHING_INVOLVED_IN_URETERIC_BUD_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRANCHING_INVOLVED_IN_URETERIC_BUD_MORPHOGENESIS","description":"The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."} {"geneset":"GO_VASCULAR_SMOOTH_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASCULAR_SMOOTH_MUSCLE_CONTRACTION","description":"A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_WOUNDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_WOUNDING","description":"Any process that modulates the frequency, rate or extent of response to wounding."} {"geneset":"GO_POSITIVE_T_CELL_SELECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_T_CELL_SELECTION","description":"The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ARSENIC_CONTAINING_SUBSTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ARSENIC_CONTAINING_SUBSTANCE","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides."} {"geneset":"GO_POSITIVE_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS","description":"Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."} {"geneset":"GO_POSITIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of stem cell differentiation."} {"geneset":"GO_REGULATION_OF_HEART_RATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEART_RATE","description":"Any process that modulates the frequency or rate of heart contraction."} {"geneset":"GO_RESPONSE_TO_PLATELET_DERIVED_GROWTH_FACTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PLATELET_DERIVED_GROWTH_FACTOR","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus."} {"geneset":"GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway."} {"geneset":"GO_INTRASPECIES_INTERACTION_BETWEEN_ORGANISMS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRASPECIES_INTERACTION_BETWEEN_ORGANISMS","description":"Any process in which an organism has an effect on an organism of the same species."} {"geneset":"GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND","description":"Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."} {"geneset":"GO_PYRIMIDINE_RIBONUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_RIBONUCLEOTIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_REGULATION_OF_B_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_B_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of B cell differentiation."} {"geneset":"GO_TRANSCRIPTION_FROM_MITOCHONDRIAL_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FROM_MITOCHONDRIAL_PROMOTER","description":"The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase."} {"geneset":"GO_MAINTENANCE_OF_PROTEIN_LOCALIZATION_IN_ORGANELLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAINTENANCE_OF_PROTEIN_LOCALIZATION_IN_ORGANELLE","description":"Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle."} {"geneset":"GO_MRNA_3_END_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_3_END_PROCESSING","description":"Any process involved in forming the mature 3' end of an mRNA molecule."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_STRESS","description":"Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."} {"geneset":"GO_REGULATION_OF_CERAMIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CERAMIDE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process."} {"geneset":"GO_REGULATION_OF_LIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."} {"geneset":"GO_POLARIZED_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLARIZED_EPITHELIAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis."} {"geneset":"GO_INNATE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNATE_IMMUNE_RESPONSE","description":"Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens."} {"geneset":"GO_CARDIAC_RIGHT_VENTRICLE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_RIGHT_VENTRICLE_MORPHOGENESIS","description":"The process in which the right cardiac ventricle is generated and organized."} {"geneset":"GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576)."} {"geneset":"GO_DIGESTIVE_TRACT_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIGESTIVE_TRACT_MORPHOGENESIS","description":"The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed."} {"geneset":"GO_SPERM_EGG_RECOGNITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERM_EGG_RECOGNITION","description":"The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization."} {"geneset":"GO_GALACTOSE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GALACTOSE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose."} {"geneset":"GO_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR","description":"The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome."} {"geneset":"GO_REGULATION_OF_ACYL_COA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACYL_COA_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA."} {"geneset":"GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER","description":"Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter."} {"geneset":"GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_INITIATION","description":"Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation."} {"geneset":"GO_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN","description":"Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin."} {"geneset":"GO_NUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar."} {"geneset":"GO_GLYOXYLATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYOXYLATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH."} {"geneset":"GO_RELAXATION_OF_MUSCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RELAXATION_OF_MUSCLE","description":"A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain."} {"geneset":"GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL","description":"Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal."} {"geneset":"GO_CELLULAR_ANION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_ANION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of anions at the level of a cell."} {"geneset":"GO_TOXIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOXIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism."} {"geneset":"GO_COVALENT_CHROMATIN_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COVALENT_CHROMATIN_MODIFICATION","description":"The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups."} {"geneset":"GO_REGULATION_OF_N_METHYL_D_ASPARTATE_SELECTIVE_GLUTAMATE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_N_METHYL_D_ASPARTATE_SELECTIVE_GLUTAMATE_RECEPTOR_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity."} {"geneset":"GO_PURINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_ARREST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_ARREST","description":"Any process that decreases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases."} {"geneset":"GO_DNA_DEMETHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DEMETHYLATION","description":"The removal of a methyl group from one or more nucleotides within an DNA molecule."} {"geneset":"GO_POST_EMBRYONIC_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POST_EMBRYONIC_MORPHOGENESIS","description":"The process, occurring after embryonic development, by which anatomical structures are generated and organized."} {"geneset":"GO_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT","description":"The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue."} {"geneset":"GO_POSITIVE_REGULATION_OF_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RECEPTOR_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of receptor activity."} {"geneset":"GO_FC_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FC_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HOMEOSTATIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HOMEOSTATIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of a homeostatic process."} {"geneset":"GO_APPENDAGE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APPENDAGE_DEVELOPMENT","description":"The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."} {"geneset":"GO_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY","description":"Any process that modulates the frequency, rate, or extent of B cell mediated immunity."} {"geneset":"GO_REGULATION_OF_MITOCHONDRIAL_FISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOCHONDRIAL_FISSION","description":"Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."} {"geneset":"GO_NEUTRAL_LIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUTRAL_LIPID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity."} {"geneset":"GO_POSITIVE_REGULATION_OF_CATECHOLAMINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CATECHOLAMINE_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION","description":"Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."} {"geneset":"GO_REGULATION_OF_CHEMOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHEMOKINE_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of chemokine production."} {"geneset":"GO_PROTEIN_AUTOUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_AUTOUBIQUITINATION","description":"The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink."} {"geneset":"GO_PORE_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PORE_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases."} {"geneset":"GO_PROTEIN_LIPID_COMPLEX_SUBUNIT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LIPID_COMPLEX_SUBUNIT_ORGANIZATION","description":"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex."} {"geneset":"GO_NEGATIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS","description":"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."} {"geneset":"GO_4_HYDROXYPROLINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_4_HYDROXYPROLINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls."} {"geneset":"GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION","description":"Any process that modulates the frequency, rate or extent of cell cycle G1/S phase transition."} {"geneset":"GO_ANION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of anions within an organism or cell."} {"geneset":"GO_LIPOPROTEIN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOPROTEIN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."} {"geneset":"GO_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus."} {"geneset":"GO_CELLULAR_POTASSIUM_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_POTASSIUM_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell."} {"geneset":"GO_PROTEIN_MANNOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_MANNOSYLATION","description":"The addition of a mannose residue to a protein acceptor molecule."} {"geneset":"GO_REGULATION_OF_FATTY_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FATTY_ACID_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of fatty acid transport."} {"geneset":"GO_HORMONE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HORMONE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."} {"geneset":"GO_ELECTRON_TRANSPORT_CHAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ELECTRON_TRANSPORT_CHAIN","description":"A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient."} {"geneset":"GO_REGULATION_OF_CIRCADIAN_SLEEP_WAKE_CYCLE_NON_REM_SLEEP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CIRCADIAN_SLEEP_WAKE_CYCLE_NON_REM_SLEEP","description":"Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep."} {"geneset":"GO_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION","description":"Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways."} {"geneset":"GO_EXTRACELLULAR_REGULATION_OF_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_REGULATION_OF_SIGNAL_TRANSDUCTION","description":"Any regulation of signal transduction that takes place in the extracellular region."} {"geneset":"GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_GAP_FILLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_GAP_FILLING","description":"Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes."} {"geneset":"GO_GLYCOSPHINGOLIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSPHINGOLIPID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide."} {"geneset":"GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus."} {"geneset":"GO_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING","description":"The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."} {"geneset":"GO_ONE_CARBON_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ONE_CARBON_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states."} {"geneset":"GO_TRANSEPITHELIAL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSEPITHELIAL_TRANSPORT","description":"The directed movement of a substance from one side of an epithelium to the other."} {"geneset":"GO_VACUOLAR_ACIDIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLAR_ACIDIFICATION","description":"Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion."} {"geneset":"GO_CELL_DIFFERENTIATION_IN_HINDBRAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DIFFERENTIATION_IN_HINDBRAIN","description":"The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_1_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_1_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-1 production."} {"geneset":"GO_POSITIVE_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION","description":"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION","description":"Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."} {"geneset":"GO_REGULATION_OF_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION","description":"Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."} {"geneset":"GO_GLYCOPROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOPROTEIN_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."} {"geneset":"GO_REGULATION_OF_LYMPHOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LYMPHOCYTE_CHEMOTAXIS","description":"Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis."} {"geneset":"GO_RENAL_WATER_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_WATER_HOMEOSTASIS","description":"Renal process involved in the maintenance of an internal steady state of water in the body."} {"geneset":"GO_REGULATION_OF_DNA_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_METHYLATION","description":"Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine."} {"geneset":"GO_HEART_VALVE_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_VALVE_FORMATION","description":"The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."} {"geneset":"GO_MITOTIC_NUCLEAR_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_NUCLEAR_DIVISION","description":"A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation."} {"geneset":"GO_FAT_SOLUBLE_VITAMIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FAT_SOLUBLE_VITAMIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water."} {"geneset":"GO_ACTOMYOSIN_STRUCTURE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTOMYOSIN_STRUCTURE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments."} {"geneset":"GO_NUCLEOTIDE_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of nucleotide across a membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS","description":"Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."} {"geneset":"GO_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of chondrocyte differentiation."} {"geneset":"GO_REGULATION_OF_PSEUDOPODIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PSEUDOPODIUM_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of the assembly of pseudopodia."} {"geneset":"GO_PALLIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PALLIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_STRESS","description":"Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."} {"geneset":"GO_CARDIAC_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CELL_FATE_COMMITMENT","description":"The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-1 production."} {"geneset":"GO_MYOFIBRIL_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOFIBRIL_ASSEMBLY","description":"Formation of myofibrils, the repeating units of striated muscle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CHEMOTAXIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient."} {"geneset":"GO_BLOOD_COAGULATION_INTRINSIC_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLOOD_COAGULATION_INTRINSIC_PATHWAY","description":"A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X."} {"geneset":"GO_GLOMERULUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLOMERULUS_DEVELOPMENT","description":"The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment."} {"geneset":"GO_TELOMERE_MAINTENANCE_VIA_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERE_MAINTENANCE_VIA_RECOMBINATION","description":"Any recombinational process that contributes to the maintenance of proper telomeric length."} {"geneset":"GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA","description":"Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."} {"geneset":"GO_CELL_CELL_SIGNALING_INVOLVED_IN_CARDIAC_CONDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_SIGNALING_INVOLVED_IN_CARDIAC_CONDUCTION","description":"Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium."} {"geneset":"GO_CELLULAR_RESPONSE_TO_THYROID_HORMONE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_THYROID_HORMONE_STIMULUS","description":"A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus."} {"geneset":"GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid."} {"geneset":"GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB."} {"geneset":"GO_MITOCHONDRIAL_RNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_RNA_PROCESSING","description":"The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion."} {"geneset":"GO_CELLULAR_LIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_LIPID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","description":"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."} {"geneset":"GO_POSITIVE_REGULATION_OF_HAIR_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HAIR_CYCLE","description":"Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair."} {"geneset":"GO_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter."} {"geneset":"GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation."} {"geneset":"GO_MULTICELLULAR_ORGANISM_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISM_GROWTH","description":"The increase in size or mass of an entire multicellular organism, as opposed to cell growth."} {"geneset":"GO_GRANULOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GRANULOCYTE_MIGRATION","description":"The movement of a granulocyte within or between different tissues and organs of the body."} {"geneset":"GO_POSITIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."} {"geneset":"GO_NCRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NCRNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs)."} {"geneset":"GO_PHOSPHATE_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATE_ION_TRANSPORT","description":"The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION","description":"Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation."} {"geneset":"GO_REGULATION_OF_CELLULAR_EXTRAVASATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_EXTRAVASATION","description":"Any process that modulates the frequency, rate, or extent of cellular extravasation."} {"geneset":"GO_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS","description":"The process in which the anatomical structures of cardiac muscle tissue are generated and organized."} {"geneset":"GO_GRANULOCYTE_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GRANULOCYTE_ACTIVATION","description":"The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."} {"geneset":"GO_REGULATION_OF_MACROPHAGE_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MACROPHAGE_CYTOKINE_PRODUCTION","description":"Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."} {"geneset":"GO_PURINE_NUCLEOBASE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_NUCLEOBASE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine."} {"geneset":"GO_MITOTIC_G2_DNA_DAMAGE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_G2_DNA_DAMAGE_CHECKPOINT","description":"A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION","description":"Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION","description":"Any process that activates or increases the frequency, rate or extent of activation."} {"geneset":"GO_CARBOHYDRATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."} {"geneset":"GO_AMINO_SUGAR_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_SUGAR_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group."} {"geneset":"GO_POSITIVE_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."} {"geneset":"GO_REGULATION_OF_CYTOKINESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOKINESIS","description":"Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells."} {"geneset":"GO_VITAMIN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VITAMIN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."} {"geneset":"GO_POSITIVE_REGULATION_OF_NON_CANONICAL_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NON_CANONICAL_WNT_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway."} {"geneset":"GO_MUSCLE_ORGAN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_ORGAN_MORPHOGENESIS","description":"The process in which the anatomical structures of muscle are generated and organized."} {"geneset":"GO_AMINO_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_ACID_TRANSPORT","description":"The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_CELLULAR_RESPONSE_TO_EPINEPHRINE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_EPINEPHRINE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN","description":"Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin."} {"geneset":"GO_REGULATION_OF_MICROTUBULE_BASED_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MICROTUBULE_BASED_MOVEMENT","description":"Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins."} {"geneset":"GO_EXOCRINE_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXOCRINE_SYSTEM_DEVELOPMENT","description":"Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system."} {"geneset":"GO_AMINOGLYCAN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINOGLYCAN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."} {"geneset":"GO_REGULATION_OF_FEVER_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FEVER_GENERATION","description":"Any process that modulates the rate or extent of fever generation."} {"geneset":"GO_DNA_TEMPLATED_TRANSCRIPTIONAL_PREINITIATION_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_TEMPLATED_TRANSCRIPTIONAL_PREINITIATION_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription."} {"geneset":"GO_MACROPHAGE_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROPHAGE_ACTIVATION","description":"A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."} {"geneset":"GO_CARDIOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIOBLAST_DIFFERENTIATION","description":"The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."} {"geneset":"GO_CELL_CYCLE_G1_S_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CYCLE_G1_S_PHASE_TRANSITION","description":"The cell cycle process by which a cell in G1 phase commits to S phase."} {"geneset":"GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS","description":"Splicing of RNA via a series of two transesterification reactions."} {"geneset":"GO_BLOOD_VESSEL_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLOOD_VESSEL_MORPHOGENESIS","description":"The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood."} {"geneset":"GO_REGULATION_OF_URINE_VOLUME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_URINE_VOLUME","description":"Any process that modulates the amount of urine excreted from the body over a unit of time."} {"geneset":"GO_PHOTORECEPTOR_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_CELL_DEVELOPMENT","description":"Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light."} {"geneset":"GO_SYNAPTIC_TRANSMISSION_DOPAMINERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_TRANSMISSION_DOPAMINERGIC","description":"The process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."} {"geneset":"GO_PROTEIN_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_PHOSPHORYLATION","description":"The process of introducing a phosphate group on to a protein."} {"geneset":"GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system."} {"geneset":"GO_REGULATION_OF_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features."} {"geneset":"GO_MAINTENANCE_OF_GASTROINTESTINAL_EPITHELIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAINTENANCE_OF_GASTROINTESTINAL_EPITHELIUM","description":"Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents."} {"geneset":"GO_ENDOTHELIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOTHELIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."} {"geneset":"GO_DOUBLE_STRAND_BREAK_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOUBLE_STRAND_BREAK_REPAIR","description":"The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix."} {"geneset":"GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT","description":"The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_NEURON_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEURON_MIGRATION","description":"Any process that modulates the frequency, rate or extent of neuron migration."} {"geneset":"GO_METHIONINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METHIONINE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."} {"geneset":"GO_MULTI_ORGANISM_ORGANELLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTI_ORGANISM_ORGANELLE_ORGANIZATION","description":"An organelle organization which involves another organism."} {"geneset":"GO_MESONEPHRIC_TUBULE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESONEPHRIC_TUBULE_MORPHOGENESIS","description":"The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros."} {"geneset":"GO_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA","description":"The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation."} {"geneset":"GO_REGULATION_OF_CYTOKINE_SECRETION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOKINE_SECRETION_INVOLVED_IN_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of cytokine secretion contributing to an immune response."} {"geneset":"GO_RESPONSE_TO_INTERLEUKIN_1","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INTERLEUKIN_1","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus."} {"geneset":"GO_EMBRYONIC_HINDLIMB_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_HINDLIMB_MORPHOGENESIS","description":"The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal."} {"geneset":"GO_WATER_SOLUBLE_VITAMIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WATER_SOLUBLE_VITAMIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water."} {"geneset":"GO_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND","description":"A series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor."} {"geneset":"GO_RNA_CAPPING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_CAPPING","description":"The sequence of enzymatic reactions by which a cap structure is added to the 5' end of a nascent RNA polymerase II transcript. All RNA polymerase II transcripts receive a 7-methyl-G cap. Then for (at least) small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs), the7-methyl-G cap is hypermethylated to become a 2,2,7-trimethylguanosine (TMG) cap."} {"geneset":"GO_MALE_MEIOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MALE_MEIOSIS","description":"A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline."} {"geneset":"GO_LIVER_REGENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIVER_REGENERATION","description":"The regrowth of lost or destroyed liver."} {"geneset":"GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process."} {"geneset":"GO_REGULATION_OF_RENAL_SODIUM_EXCRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RENAL_SODIUM_EXCRETION","description":"Any process that modulates the amount of sodium excreted in urine over a unit of time."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response."} {"geneset":"GO_SPINAL_CORD_PATTERNING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINAL_CORD_PATTERNING","description":"The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord."} {"geneset":"GO_DNA_REPLICATION_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_REPLICATION_INITIATION","description":"The process in which DNA-dependent DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action."} {"geneset":"GO_ERYTHROCYTE_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERYTHROCYTE_MATURATION","description":"A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state."} {"geneset":"GO_ETHANOLAMINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ETHANOLAMINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it."} {"geneset":"GO_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT","description":"Any process that activates or increases the frequency, rate or extent of dendrite development."} {"geneset":"GO_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","description":"The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."} {"geneset":"GO_BASIC_AMINO_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASIC_AMINO_ACID_TRANSPORT","description":"The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_CAMP_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CAMP_MEDIATED_SIGNALING","description":"Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response."} {"geneset":"GO_CELL_MIGRATION_INVOLVED_IN_GASTRULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MIGRATION_INVOLVED_IN_GASTRULATION","description":"The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)."} {"geneset":"GO_ASTROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASTROCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."} {"geneset":"GO_PROTEIN_MONOUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_MONOUBIQUITINATION","description":"Addition of a single ubiquitin group to a protein."} {"geneset":"GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION","description":"Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation."} {"geneset":"GO_FACE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FACE_DEVELOPMENT","description":"The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head."} {"geneset":"GO_RNA_DESTABILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_DESTABILIZATION","description":"Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes."} {"geneset":"GO_RESPONSE_TO_ESTROGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ESTROGEN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics."} {"geneset":"GO_DETOXIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETOXIFICATION","description":"Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."} {"geneset":"GO_REGULATION_OF_OSTEOBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OSTEOBLAST_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of osteoblast proliferation."} {"geneset":"GO_CILIUM_OR_FLAGELLUM_DEPENDENT_CELL_MOTILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIUM_OR_FLAGELLUM_DEPENDENT_CELL_MOTILITY","description":"Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella."} {"geneset":"GO_VERY_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VERY_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22."} {"geneset":"GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE","description":"The directed movement of a protein to a specific location in a membrane."} {"geneset":"GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION","description":"Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals."} {"geneset":"GO_REGULATION_OF_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PEPTIDASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","description":"Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity."} {"geneset":"GO_BROWN_FAT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BROWN_FAT_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."} {"geneset":"GO_LIPID_TRANSLOCATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_TRANSLOCATION","description":"The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."} {"geneset":"GO_INOSITOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms."} {"geneset":"GO_REGULATION_OF_CENTROSOME_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CENTROSOME_CYCLE","description":"Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor."} {"geneset":"GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS","description":"Any process that modulates the frequency, rate, or extent of an immune system process."} {"geneset":"GO_PROTEIN_ADP_RIBOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_ADP_RIBOSYLATION","description":"The transfer, from NAD, of ADP-ribose to protein amino acids."} {"geneset":"GO_CELLULAR_SODIUM_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_SODIUM_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT","description":"Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."} {"geneset":"GO_CHONDROITIN_SULFATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHONDROITIN_SULFATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."} {"geneset":"GO_PROTEIN_SUMOYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SUMOYLATION","description":"The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein."} {"geneset":"GO_MEGAKARYOCYTE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEGAKARYOCYTE_DEVELOPMENT","description":"The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow."} {"geneset":"GO_REGULATION_OF_HISTONE_H3_K9_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HISTONE_H3_K9_METHYLATION","description":"Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3."} {"geneset":"GO_VASODILATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASODILATION","description":"An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE","description":"Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION","description":"Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."} {"geneset":"GO_NEURONAL_ION_CHANNEL_CLUSTERING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURONAL_ION_CHANNEL_CLUSTERING","description":"The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation."} {"geneset":"GO_POSITIVE_REGULATION_OF_AXON_EXTENSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_AXON_EXTENSION","description":"Any process that activates or increases the frequency, rate or extent of axon extension."} {"geneset":"GO_REGULATION_OF_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ION_HOMEOSTASIS","description":"Any process that modulates the frequency, rate or extent of ion homeostasis."} {"geneset":"GO_PIGMENT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIGMENT_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte."} {"geneset":"GO_ORGAN_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGAN_GROWTH","description":"The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function."} {"geneset":"GO_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of lymphocyte differentiation."} {"geneset":"GO_REGULATION_OF_BONE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BONE_REMODELING","description":"Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity."} {"geneset":"GO_GLUCOCORTICOID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOCORTICOID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."} {"geneset":"GO_REGULATION_OF_T_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of T cell proliferation."} {"geneset":"GO_NERVE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NERVE_DEVELOPMENT","description":"The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure."} {"geneset":"GO_REGULATION_OF_NEUROBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUROBLAST_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of neuroblast proliferation."} {"geneset":"GO_DETECTION_OF_MOLECULE_OF_BACTERIAL_ORIGIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_MOLECULE_OF_BACTERIAL_ORIGIN","description":"The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal."} {"geneset":"GO_PHAGOSOME_ACIDIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOSOME_ACIDIFICATION","description":"Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion."} {"geneset":"GO_REGULATION_OF_CELL_SIZE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_SIZE","description":"Any process that modulates the size of a cell."} {"geneset":"GO_TETRAPYRROLE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TETRAPYRROLE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."} {"geneset":"GO_REGULATION_OF_CENTROSOME_DUPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CENTROSOME_DUPLICATION","description":"Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."} {"geneset":"GO_VENTRAL_SPINAL_CORD_INTERNEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRAL_SPINAL_CORD_INTERNEURON_DIFFERENTIATION","description":"The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY","description":"Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor."} {"geneset":"GO_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet."} {"geneset":"GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development."} {"geneset":"GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION","description":"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex."} {"geneset":"GO_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL","description":"Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."} {"geneset":"GO_MULTICELLULAR_ORGANISMAL_WATER_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISMAL_WATER_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism."} {"geneset":"GO_REGULATION_OF_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME","description":"Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs."} {"geneset":"GO_KERATAN_SULFATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KERATAN_SULFATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."} {"geneset":"GO_BLASTOCYST_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLASTOCYST_DEVELOPMENT","description":"The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm."} {"geneset":"GO_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS","description":"Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus."} {"geneset":"GO_CHROMATIN_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_ORGANIZATION","description":"Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYTOKINESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYTOKINESIS","description":"Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells."} {"geneset":"GO_EPHRIN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPHRIN_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin."} {"geneset":"GO_ORGANIC_ANION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ANION_TRANSPORT","description":"The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage."} {"geneset":"GO_STAT_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STAT_CASCADE","description":"An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with activation of STAT proteins by kinases, proceeds through dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins."} {"geneset":"GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus."} {"geneset":"GO_BICARBONATE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BICARBONATE_TRANSPORT","description":"The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL","description":"Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION","description":"Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways."} {"geneset":"GO_SEGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEGMENTATION","description":"The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis."} {"geneset":"GO_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY","description":"Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins."} {"geneset":"GO_POSITIVE_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of T cell cytokine production."} {"geneset":"GO_PYRIMIDINE_CONTAINING_COMPOUND_SALVAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_CONTAINING_COMPOUND_SALVAGE","description":"Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis."} {"geneset":"GO_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation."} {"geneset":"GO_TRNA_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_METHYLATION","description":"The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule."} {"geneset":"GO_INTERACTION_WITH_HOST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERACTION_WITH_HOST","description":"An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism."} {"geneset":"GO_GASTRULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GASTRULATION","description":"A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm."} {"geneset":"GO_RESPONSE_TO_UV","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_UV","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."} {"geneset":"GO_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT","description":"Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development."} {"geneset":"GO_SKIN_EPIDERMIS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKIN_EPIDERMIS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure."} {"geneset":"GO_VIRAL_GENOME_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VIRAL_GENOME_REPLICATION","description":"Any process involved directly in viral genome replication, including viral nucleotide metabolism."} {"geneset":"GO_NUCLEOTIDE_EXCISION_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_EXCISION_REPAIR","description":"A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts)."} {"geneset":"GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA","description":"Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."} {"geneset":"GO_GOLGI_TO_ENDOSOME_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_TO_ENDOSOME_TRANSPORT","description":"The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes."} {"geneset":"GO_REGULATION_OF_MUSCLE_HYPERTROPHY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MUSCLE_HYPERTROPHY","description":"Any process that modulates the frequency, rate or extent of muscle hypertrophy."} {"geneset":"GO_CARBOHYDRATE_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_TRANSMEMBRANE_TRANSPORT","description":"The process in which a carbohydrate is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."} {"geneset":"GO_SULFUR_COMPOUND_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFUR_COMPOUND_TRANSPORT","description":"The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_FATTY_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."} {"geneset":"GO_HEART_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_FORMATION","description":"The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable."} {"geneset":"GO_RECEPTOR_INTERNALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_INTERNALIZATION","description":"A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION","description":"Any process that activates or increases the frequency, rate, or extent of mast cell activation."} {"geneset":"GO_REGULATION_OF_ODONTOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ODONTOGENESIS","description":"Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth."} {"geneset":"GO_MULTICELLULAR_ORGANISM_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISM_METABOLIC_PROCESS","description":"The chemical reactions and pathways in a single multicellular organism that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required."} {"geneset":"GO_PARTURITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PARTURITION","description":"The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway."} {"geneset":"GO_ALPHA_LINOLENIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALPHA_LINOLENIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2."} {"geneset":"GO_REGULATION_OF_ARP2_3_COMPLEX_MEDIATED_ACTIN_NUCLEATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ARP2_3_COMPLEX_MEDIATED_ACTIN_NUCLEATION","description":"Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins."} {"geneset":"GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS","description":"Any biological process involved in the maintenance of the steady-state number of cells within a population of cells."} {"geneset":"GO_MEIOTIC_CHROMOSOME_SEPARATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEIOTIC_CHROMOSOME_SEPARATION","description":"The process in which chromosomes are physically detached from each other during meiosis."} {"geneset":"GO_REGULATION_OF_CALCINEURIN_NFAT_SIGNALING_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CALCINEURIN_NFAT_SIGNALING_CASCADE","description":"Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade."} {"geneset":"GO_DIOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic."} {"geneset":"GO_REGULATION_OF_RYANODINE_SENSITIVE_CALCIUM_RELEASE_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RYANODINE_SENSITIVE_CALCIUM_RELEASE_CHANNEL_ACTIVITY","description":"Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_OXYGEN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXYGEN_TRANSPORT","description":"The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_LIPID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPID_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRIGLYCERIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRIGLYCERIDE_BIOSYNTHETIC_PROCESS","description":"Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol."} {"geneset":"GO_REGULATION_OF_REPRODUCTIVE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_REPRODUCTIVE_PROCESS","description":"Any process that modulates the frequency, rate or extent of reproductive process."} {"geneset":"GO_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS","description":"Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)."} {"geneset":"GO_POSITIVE_REGULATION_OF_HORMONE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HORMONE_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell."} {"geneset":"GO_ORGAN_INDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGAN_INDUCTION","description":"The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ."} {"geneset":"GO_DNA_STRAND_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_STRAND_ELONGATION","description":"The DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3' end of an existing DNA stand."} {"geneset":"GO_NEURON_PROJECTION_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_MORPHOGENESIS","description":"The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites."} {"geneset":"GO_REGULATION_OF_CELL_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_DIVISION","description":"Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells."} {"geneset":"GO_MULTIVESICULAR_BODY_SORTING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTIVESICULAR_BODY_SORTING_PATHWAY","description":"A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded."} {"geneset":"GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY","description":"Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity."} {"geneset":"GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS","description":"The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences."} {"geneset":"GO_NOTCH_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NOTCH_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_OUTER_DYNEIN_ARM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OUTER_DYNEIN_ARM_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS","description":"Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus."} {"geneset":"GO_RESPONSE_TO_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_RADIATION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation."} {"geneset":"GO_BILE_ACID_AND_BILE_SALT_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BILE_ACID_AND_BILE_SALT_TRANSPORT","description":"The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_HEART_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_DEVELOPMENT","description":"The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."} {"geneset":"GO_TISSUE_REGENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TISSUE_REGENERATION","description":"The regrowth of lost or destroyed tissues."} {"geneset":"GO_MESODERM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESODERM_MORPHOGENESIS","description":"The process in which the anatomical structures of the mesoderm are generated and organized."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling."} {"geneset":"GO_RECEPTOR_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."} {"geneset":"GO_NUCLEOSIDE_SALVAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_SALVAGE","description":"Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis."} {"geneset":"GO_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INFLAMMATORY_RESPONSE","description":"The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages."} {"geneset":"GO_TRNA_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_TRANSPORT","description":"The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING","description":"Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ANOIKIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ANOIKIS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of anoikis."} {"geneset":"GO_POSITIVE_REGULATION_OF_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LIGASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate."} {"geneset":"GO_LACTATE_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LACTATE_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of lactate across a membrane by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_HYPOXIA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_HYPOXIA","description":"Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus."} {"geneset":"GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells."} {"geneset":"GO_PIGMENT_GRANULE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIGMENT_GRANULE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_13_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_13_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-13 production."} {"geneset":"GO_REGULATION_OF_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CYCLE","description":"Any process that modulates the rate or extent of progression through the cell cycle."} {"geneset":"GO_TUBE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TUBE_DEVELOPMENT","description":"The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts."} {"geneset":"GO_LOCOMOTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOCOMOTION","description":"Self-propelled movement of a cell or organism from one location to another."} {"geneset":"GO_ACROSOME_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACROSOME_ASSEMBLY","description":"The formation of the acrosome from the spermatid Golgi."} {"geneset":"GO_REGULATION_OF_INOSITOL_PHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INOSITOL_PHOSPHATE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."} {"geneset":"GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR","description":"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator."} {"geneset":"GO_POSITIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT","description":"Any process that activates or increases the frequency, rate or extent of epidermis development."} {"geneset":"GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus."} {"geneset":"GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of protein complex assembly."} {"geneset":"GO_CALCIUM_ION_REGULATED_EXOCYTOSIS_OF_NEUROTRANSMITTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ION_REGULATED_EXOCYTOSIS_OF_NEUROTRANSMITTER","description":"The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels."} {"geneset":"GO_REGULATION_OF_REGULATED_SECRETORY_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_REGULATED_SECRETORY_PATHWAY","description":"Any process that modulates the frequency, rate or extent of regulated secretory pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_RECEPTOR_INTERNALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RECEPTOR_INTERNALIZATION","description":"Any process that activates or increases the frequency, rate or extent of receptor internalization."} {"geneset":"GO_CARDIAC_MUSCLE_CELL_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_MUSCLE_CELL_CONTRACTION","description":"The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell."} {"geneset":"GO_AMINO_SUGAR_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_SUGAR_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group."} {"geneset":"GO_POSITIVE_REGULATION_OF_MACROPHAGE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MACROPHAGE_CHEMOTAXIS","description":"Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."} {"geneset":"GO_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the frequency, rate, or extent of B cell apoptotic process."} {"geneset":"GO_MITOCHONDRIAL_RNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_RNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion."} {"geneset":"GO_MODULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL","description":"Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."} {"geneset":"GO_NUCLEUS_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEUS_LOCALIZATION","description":"Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell."} {"geneset":"GO_RESPONSE_TO_HEPATOCYTE_GROWTH_FACTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_HEPATOCYTE_GROWTH_FACTOR","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus."} {"geneset":"GO_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS","description":"Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis."} {"geneset":"GO_ORGANELLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."} {"geneset":"GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT","description":"A mitotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction."} {"geneset":"GO_FATTY_ACID_DERIVATIVE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_DERIVATIVE_TRANSPORT","description":"The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_NATURAL_KILLER_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NATURAL_KILLER_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."} {"geneset":"GO_CARDIAC_VENTRICLE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_VENTRICLE_DEVELOPMENT","description":"The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart."} {"geneset":"GO_MALE_MEIOSIS_I","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MALE_MEIOSIS_I","description":"A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline."} {"geneset":"GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone."} {"geneset":"GO_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS","description":"Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose."} {"geneset":"GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport."} {"geneset":"GO_POSITIVE_REGULATION_OF_HEART_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HEART_CONTRACTION","description":"Any process that activates or increases the frequency, rate or extent of heart contraction."} {"geneset":"GO_CELLULAR_RESPONSE_TO_PROSTAGLANDIN_E_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_PROSTAGLANDIN_E_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus."} {"geneset":"GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS","description":"A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered."} {"geneset":"GO_PURINE_NUCLEOSIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_NUCLEOSIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."} {"geneset":"GO_FEMALE_SEX_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FEMALE_SEX_DIFFERENTIATION","description":"The establishment of the sex of a female organism by physical differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_CIRCADIAN_RHYTHM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CIRCADIAN_RHYTHM","description":"Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior."} {"geneset":"GO_ECTODERMAL_PLACODE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ECTODERMAL_PLACODE_DEVELOPMENT","description":"The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm."} {"geneset":"GO_POSITIVE_REGULATION_OF_PHAGOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PHAGOCYTOSIS","description":"Any process that activates or increases the frequency, rate or extent of phagocytosis."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ETHANOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ETHANOL","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus."} {"geneset":"GO_RESPIRATORY_BURST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPIRATORY_BURST","description":"A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_REPAIR","description":"Any process that activates or increases the frequency, rate or extent of DNA repair."} {"geneset":"GO_CEREBRAL_CORTEX_GABAERGIC_INTERNEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBRAL_CORTEX_GABAERGIC_INTERNEURON_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex."} {"geneset":"GO_NIK_NF_KAPPAB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NIK_NF_KAPPAB_SIGNALING","description":"The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52)."} {"geneset":"GO_MAMMARY_GLAND_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAMMARY_GLAND_DEVELOPMENT","description":"The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SECRETION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."} {"geneset":"GO_MITOTIC_SPINDLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_SPINDLE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle."} {"geneset":"GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."} {"geneset":"GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION","description":"Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."} {"geneset":"GO_MAINTENANCE_OF_CELL_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAINTENANCE_OF_CELL_POLARITY","description":"The maintenance of established anisotropic intracellular organization or cell growth patterns."} {"geneset":"GO_MRNA_CLEAVAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_CLEAVAGE","description":"Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner."} {"geneset":"GO_POSITIVE_REGULATION_OF_URINE_VOLUME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_URINE_VOLUME","description":"Any process that increases the amount of urine excreted from the body over a unit of time."} {"geneset":"GO_GLYCINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycine, aminoethanoic acid."} {"geneset":"GO_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of chemokine production."} {"geneset":"GO_REGULATION_OF_GLYCOGEN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLYCOGEN_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen."} {"geneset":"GO_ESTABLISHMENT_OF_NUCLEUS_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_NUCLEUS_LOCALIZATION","description":"The directed movement of the nucleus to a specific location within a cell."} {"geneset":"GO_ENDODERM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDODERM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues."} {"geneset":"GO_VESICLE_COATING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_COATING","description":"A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination."} {"geneset":"GO_CYTOPLASMIC_SEQUESTERING_OF_TRANSCRIPTION_FACTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_SEQUESTERING_OF_TRANSCRIPTION_FACTOR","description":"The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus."} {"geneset":"GO_PROTEIN_TRANSPORT_ALONG_MICROTUBULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TRANSPORT_ALONG_MICROTUBULE","description":"The directed movement of a protein along a microtubule, mediated by motor proteins."} {"geneset":"GO_AUDITORY_RECEPTOR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AUDITORY_RECEPTOR_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of an auditory hair cell."} {"geneset":"GO_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide."} {"geneset":"GO_CAMERA_TYPE_EYE_PHOTORECEPTOR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CAMERA_TYPE_EYE_PHOTORECEPTOR_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye."} {"geneset":"GO_REGULATION_OF_GROWTH_HORMONE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GROWTH_HORMONE_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell."} {"geneset":"GO_PYRIMIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."} {"geneset":"GO_MICROGLIAL_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROGLIAL_CELL_ACTIVATION","description":"The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."} {"geneset":"GO_OXIDATION_REDUCTION_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDATION_REDUCTION_PROCESS","description":"A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons."} {"geneset":"GO_RESPONSE_TO_ATP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ATP","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus."} {"geneset":"GO_WATER_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WATER_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of water within an organism or cell."} {"geneset":"GO_VOCALIZATION_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOCALIZATION_BEHAVIOR","description":"The behavior in which an organism produces sounds by a mechanism involving its respiratory system."} {"geneset":"GO_GOLGI_TO_PLASMA_MEMBRANE_PROTEIN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_TO_PLASMA_MEMBRANE_PROTEIN_TRANSPORT","description":"The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane."} {"geneset":"GO_LONG_TERM_MEMORY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LONG_TERM_MEMORY","description":"The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation."} {"geneset":"GO_ADRENAL_GLAND_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADRENAL_GLAND_DEVELOPMENT","description":"The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells."} {"geneset":"GO_CELLULAR_RESPONSE_TO_CHOLESTEROL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_CHOLESTEROL","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity."} {"geneset":"GO_VIRAL_LIFE_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VIRAL_LIFE_CYCLE","description":"A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome."} {"geneset":"GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION","description":"Any process that modulates the frequency, rate or extent of smooth muscle cell migration."} {"geneset":"GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK","description":"The synchronization of a circadian rhythm to environmental time cues such as light."} {"geneset":"GO_REGULATION_OF_CGMP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CGMP_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP."} {"geneset":"GO_REGULATION_OF_CYTOKINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOKINE_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell."} {"geneset":"GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STARVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STARVATION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids."} {"geneset":"GO_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of immunoglobulin production."} {"geneset":"GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MITOCHONDRION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MITOCHONDRION","description":"Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion."} {"geneset":"GO_REGULATION_OF_SENSORY_PERCEPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SENSORY_PERCEPTION","description":"Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal."} {"geneset":"GO_REGULATION_OF_REGULATORY_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_REGULATORY_T_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells."} {"geneset":"GO_CHONDROITIN_SULFATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHONDROITIN_SULFATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."} {"geneset":"GO_RESPONSE_TO_AUDITORY_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_AUDITORY_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus."} {"geneset":"GO_PRESYNAPTIC_PROCESS_INVOLVED_IN_SYNAPTIC_TRANSMISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRESYNAPTIC_PROCESS_INVOLVED_IN_SYNAPTIC_TRANSMISSION","description":"The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission."} {"geneset":"GO_PROTEIN_UBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_UBIQUITINATION","description":"The process in which one or more ubiquitin groups are added to a protein."} {"geneset":"GO_MAINTENANCE_OF_CELL_NUMBER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAINTENANCE_OF_CELL_NUMBER","description":"Any process by which the numbers of cells of a particular type in a tissue are maintained."} {"geneset":"GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION","description":"The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization."} {"geneset":"GO_COENZYME_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COENZYME_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed."} {"geneset":"GO_EPIBOLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPIBOLY","description":"The expansion of one cell sheet over other cells or yolk."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response."} {"geneset":"GO_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS","description":"Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis."} {"geneset":"GO_CENTRAL_NERVOUS_SYSTEM_PROJECTION_NEURON_AXONOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTRAL_NERVOUS_SYSTEM_PROJECTION_NEURON_AXONOGENESIS","description":"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region."} {"geneset":"GO_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS","description":"An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes."} {"geneset":"GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine."} {"geneset":"GO_ORGANOPHOSPHATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANOPHOSPHATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BEHAVIOR","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."} {"geneset":"GO_POSITIVE_REGULATION_OF_P38MAPK_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_P38MAPK_CASCADE","description":"Any process that activates or increases the frequency, rate or extent of p38MAPK cascade."} {"geneset":"GO_MEMBRANE_PROTEIN_INTRACELLULAR_DOMAIN_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_PROTEIN_INTRACELLULAR_DOMAIN_PROTEOLYSIS","description":"The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain."} {"geneset":"GO_POSITIVE_REGULATION_OF_CHROMATIN_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CHROMATIN_MODIFICATION","description":"Any process that activates or increases the frequency, rate or extent of chromatin modification."} {"geneset":"GO_RESPONSE_TO_CAFFEINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_CAFFEINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them."} {"geneset":"GO_DISTAL_TUBULE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DISTAL_TUBULE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule."} {"geneset":"GO_CRANIAL_SKELETAL_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CRANIAL_SKELETAL_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus."} {"geneset":"GO_DNA_TEMPLATED_TRANSCRIPTION_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_TEMPLATED_TRANSCRIPTION_INITIATION","description":"Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription."} {"geneset":"GO_REGULATION_OF_HORMONE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HORMONE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones."} {"geneset":"GO_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEUROTRANSMITTER_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEUROTRANSMITTER_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter."} {"geneset":"GO_GENETIC_IMPRINTING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GENETIC_IMPRINTING","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence."} {"geneset":"GO_CELLULAR_PROCESS_INVOLVED_IN_REPRODUCTION_IN_MULTICELLULAR_ORGANISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_PROCESS_INVOLVED_IN_REPRODUCTION_IN_MULTICELLULAR_ORGANISM","description":"A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_DEATH","description":"Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death."} {"geneset":"GO_TROPHOBLAST_GIANT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TROPHOBLAST_GIANT_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua."} {"geneset":"GO_ER_ASSOCIATED_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ER_ASSOCIATED_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins."} {"geneset":"GO_ISOTYPE_SWITCHING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ISOTYPE_SWITCHING","description":"The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus."} {"geneset":"GO_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM","description":"Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism."} {"geneset":"GO_SIGNAL_RELEASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_RELEASE","description":"The process in which a signal is secreted or discharged into the extracellular medium from a cellular source."} {"geneset":"GO_REGULATION_OF_EXOSOMAL_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXOSOMAL_SECRETION","description":"Any process that modulates the frequency, rate or extent of exosomal secretion."} {"geneset":"GO_REGULATION_OF_INCLUSION_BODY_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INCLUSION_BODY_ASSEMBLY","description":"Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body."} {"geneset":"GO_REGULATION_OF_CHRONIC_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHRONIC_INFLAMMATORY_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of a chronic inflammatory response."} {"geneset":"GO_REGULATION_OF_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of T cell differentiation."} {"geneset":"GO_ADAPTIVE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADAPTIVE_IMMUNE_RESPONSE","description":"An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory)."} {"geneset":"GO_TRANSLESION_SYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLESION_SYNTHESIS","description":"The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide."} {"geneset":"GO_REGULATION_OF_GLOMERULUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLOMERULUS_DEVELOPMENT","description":"Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."} {"geneset":"GO_METHIONINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METHIONINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."} {"geneset":"GO_DICARBOXYLIC_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DICARBOXYLIC_ACID_TRANSPORT","description":"The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development."} {"geneset":"GO_DNA_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_RECOMBINATION","description":"Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."} {"geneset":"GO_POST_TRANSLATIONAL_PROTEIN_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POST_TRANSLATIONAL_PROTEIN_MODIFICATION","description":"The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome."} {"geneset":"GO_PROTEIN_FOLDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_FOLDING","description":"The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure."} {"geneset":"GO_GLYCOSPHINGOLIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSPHINGOLIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide."} {"geneset":"GO_REGULATION_OF_MRNA_POLYADENYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MRNA_POLYADENYLATION","description":"Any process that modulates the frequency, rate or extent of mRNA polyadenylation."} {"geneset":"GO_NEURON_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_MIGRATION","description":"The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature."} {"geneset":"GO_REGULATION_OF_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE","description":"Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_TUMOR_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_TUMOR_CELL","description":"Any process that activates or increases the frequency, rate, or extent of a response to tumor cell."} {"geneset":"GO_REGULATION_OF_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTION_POTENTIAL","description":"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."} {"geneset":"GO_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS","description":"Any process that modulates the frequency, rate or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_TISSUE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TISSUE_REMODELING","description":"Any process that activates or increases the frequency, rate, or extent of tissue remodeling."} {"geneset":"GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS","description":"Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome."} {"geneset":"GO_DORSAL_VENTRAL_NEURAL_TUBE_PATTERNING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DORSAL_VENTRAL_NEURAL_TUBE_PATTERNING","description":"The process in which the neural tube is regionalized in the dorsoventral axis."} {"geneset":"GO_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of binding to toll-like receptor 4."} {"geneset":"GO_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation."} {"geneset":"GO_CALCIUM_ION_REGULATED_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ION_REGULATED_EXOCYTOSIS","description":"The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels."} {"geneset":"GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus."} {"geneset":"GO_RETINAL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINAL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A."} {"geneset":"GO_MOLTING_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MOLTING_CYCLE","description":"The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc."} {"geneset":"GO_CHROMOSOME_ORGANIZATION_INVOLVED_IN_MEIOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_ORGANIZATION_INVOLVED_IN_MEIOTIC_CELL_CYCLE","description":"A process of chromosome organization that is involved in a meiotic cell cycle."} {"geneset":"GO_POSITIVE_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION","description":"Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."} {"geneset":"GO_OOCYTE_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OOCYTE_MATURATION","description":"A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization."} {"geneset":"GO_DNA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_BIOSYNTHETIC_PROCESS","description":"The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one."} {"geneset":"GO_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING","description":"The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate."} {"geneset":"GO_SPERMATID_NUCLEUS_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERMATID_NUCLEUS_DIFFERENTIATION","description":"The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization."} {"geneset":"GO_MULTI_ORGANISM_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTI_ORGANISM_LOCALIZATION","description":"A localization which involves another organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_DEATH","description":"Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death."} {"geneset":"GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription."} {"geneset":"GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH","description":"Any process that activates, maintains or increases the rate of developmental growth."} {"geneset":"GO_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of erythrocyte differentiation."} {"geneset":"GO_METANEPHRIC_NEPHRON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METANEPHRIC_NEPHRON_DEVELOPMENT","description":"The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of a neurophysiological process."} {"geneset":"GO_TRACHEA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRACHEA_DEVELOPMENT","description":"The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches."} {"geneset":"GO_NEUROGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROGENESIS","description":"Generation of cells within the nervous system."} {"geneset":"GO_POSITIVE_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_AMINE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_AMINE_TRANSPORT","description":"Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system."} {"geneset":"GO_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT","description":"Any apoptotic process that is involved in anatomical structure development."} {"geneset":"GO_RESPONSE_TO_LOW_DENSITY_LIPOPROTEIN_PARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_LOW_DENSITY_LIPOPROTEIN_PARTICLE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus."} {"geneset":"GO_RETINOIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINOIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A."} {"geneset":"GO_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."} {"geneset":"GO_REGULATION_OF_PROTEIN_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_ACETYLATION","description":"Any process that modulates the frequency, rate or extent of protein acetylation."} {"geneset":"GO_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS","description":"Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system."} {"geneset":"GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP)."} {"geneset":"GO_SODIUM_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell."} {"geneset":"GO_CELLULAR_RESPONSE_TO_HEAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_HEAT","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."} {"geneset":"GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_LAMELLIPODIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LAMELLIPODIUM_ASSEMBLY","description":"Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."} {"geneset":"GO_PURINE_NUCLEOTIDE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_NUCLEOTIDE_TRANSPORT","description":"The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell."} {"geneset":"GO_REGULATION_OF_PROTEIN_STABILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_STABILITY","description":"Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation."} {"geneset":"GO_REGULATION_OF_DNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA."} {"geneset":"GO_NADH_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NADH_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid."} {"geneset":"GO_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm."} {"geneset":"GO_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION","description":"Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels."} {"geneset":"GO_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY","description":"The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines."} {"geneset":"GO_TELOMERE_MAINTENANCE_VIA_TELOMERASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERE_MAINTENANCE_VIA_TELOMERASE","description":"The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase."} {"geneset":"GO_REGULATION_OF_GRANULOCYTE_MACROPHAGE_COLONY_STIMULATING_FACTOR_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GRANULOCYTE_MACROPHAGE_COLONY_STIMULATING_FACTOR_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production."} {"geneset":"GO_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GROWTH","description":"The increase in size or mass of an entire organism, a part of an organism or a cell."} {"geneset":"GO_EMBRYONIC_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_MORPHOGENESIS","description":"The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants."} {"geneset":"GO_LIPID_PARTICLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_PARTICLE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISM_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISM_GROWTH","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process."} {"geneset":"GO_OOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OOCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete."} {"geneset":"GO_JAK_STAT_CASCADE_INVOLVED_IN_GROWTH_HORMONE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_JAK_STAT_CASCADE_INVOLVED_IN_GROWTH_HORMONE_SIGNALING_PATHWAY","description":"The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes."} {"geneset":"GO_INTERSTRAND_CROSS_LINK_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERSTRAND_CROSS_LINK_REPAIR","description":"Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication."} {"geneset":"GO_REGULATION_OF_STEM_CELL_POPULATION_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STEM_CELL_POPULATION_MAINTENANCE","description":"Any process that modulates the frequency, rate or extent of stem cell population maintenance."} {"geneset":"GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING","description":"Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening."} {"geneset":"GO_GANGLIOSIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GANGLIOSIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues."} {"geneset":"GO_POSITIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE","description":"Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response."} {"geneset":"GO_ANDROGEN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANDROGEN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development."} {"geneset":"GO_INDOLE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INDOLE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton."} {"geneset":"GO_NEGATIVE_REGULATION_OF_T_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_T_CELL_PROLIFERATION","description":"Any process that stops, prevents or reduces the rate or extent of T cell proliferation."} {"geneset":"GO_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of T cell cytokine production."} {"geneset":"GO_REGULATION_OF_CHEMOKINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHEMOKINE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines."} {"geneset":"GO_POSITIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT","description":"Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."} {"geneset":"GO_MUSCLE_ATROPHY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_ATROPHY","description":"A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."} {"geneset":"GO_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS","description":"Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY","description":"Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."} {"geneset":"GO_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS","description":"Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_DEPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_DEPHOSPHORYLATION","description":"The process of removing one or more phosphate groups from a phosphatidylinositol."} {"geneset":"GO_DIGESTIVE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIGESTIVE_SYSTEM_PROCESS","description":"A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."} {"geneset":"GO_CALCIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ION_TRANSPORT","description":"The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I","description":"The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY","description":"Any process that stops or reduces the activity of an enzyme."} {"geneset":"GO_PYRIMIDINE_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."} {"geneset":"GO_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","description":"The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure."} {"geneset":"GO_LEUKOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_APOPTOTIC_PROCESS","description":"Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EMBRYONIC_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EMBRYONIC_DEVELOPMENT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development."} {"geneset":"GO_POSITIVE_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."} {"geneset":"GO_PEPTIDYL_GLUTAMIC_ACID_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_GLUTAMIC_ACID_MODIFICATION","description":"The modification of peptidyl-glutamic acid."} {"geneset":"GO_REGULATION_OF_NOTCH_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NOTCH_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the Notch signaling pathway."} {"geneset":"GO_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYTOKINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYTOKINE_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the regulated release of cytokines from a cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MAST_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MAST_CELL_ACTIVATION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation."} {"geneset":"GO_MICROTUBULE_BUNDLE_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_BUNDLE_FORMATION","description":"A process that results in a parallel arrangement of microtubules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity."} {"geneset":"GO_EMBRYONIC_SKELETAL_JOINT_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_SKELETAL_JOINT_DEVELOPMENT","description":"The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure."} {"geneset":"GO_RESPONSE_TO_CARBOHYDRATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_CARBOHYDRATE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus."} {"geneset":"GO_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of organic acid across a membrane."} {"geneset":"GO_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYSTEM_PROCESS","description":"A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective."} {"geneset":"GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis."} {"geneset":"GO_REGULATION_OF_PROTEIN_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_MATURATION","description":"Any process that modulates the frequency, rate or extent of protein maturation."} {"geneset":"GO_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group."} {"geneset":"GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube."} {"geneset":"GO_POSITIVE_REGULATION_OF_VASCULAR_PERMEABILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VASCULAR_PERMEABILITY","description":"Any process that increases the extent to which blood vessels can be pervaded by fluid."} {"geneset":"GO_EAR_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EAR_MORPHOGENESIS","description":"The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals."} {"geneset":"GO_MOVEMENT_OF_CELL_OR_SUBCELLULAR_COMPONENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MOVEMENT_OF_CELL_OR_SUBCELLULAR_COMPONENT","description":"The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore."} {"geneset":"GO_NEURON_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_CELL_CELL_ADHESION","description":"The attachment of a neuron to another cell via adhesion molecules."} {"geneset":"GO_TERMINATION_OF_RNA_POLYMERASE_II_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TERMINATION_OF_RNA_POLYMERASE_II_TRANSCRIPTION","description":"The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed."} {"geneset":"GO_CELLULAR_RESPONSE_TO_NITROGEN_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_NITROGEN_LEVELS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen."} {"geneset":"GO_SYNAPTIC_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_SIGNALING","description":"Cell-cell signaling to or from a synapse."} {"geneset":"GO_MITOTIC_CELL_CYCLE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_CELL_CYCLE_CHECKPOINT","description":"A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage."} {"geneset":"GO_RESPONSE_TO_LIPID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_LIPID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus."} {"geneset":"GO_RESPONSE_TO_NICOTINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_NICOTINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MACROAUTOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MACROAUTOPHAGY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy."} {"geneset":"GO_POSITIVE_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process."} {"geneset":"GO_REGULATION_OF_MITOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOPHAGY","description":"Any process that modulates the frequency, rate or extent of mitochondrion degradation (mitophagy)."} {"geneset":"GO_FATTY_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."} {"geneset":"GO_ACTIVATION_OF_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_IMMUNE_RESPONSE","description":"Any process that initiates an immune response."} {"geneset":"GO_VASCULATURE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASCULATURE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein."} {"geneset":"GO_CELL_CYCLE_G2_M_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CYCLE_G2_M_PHASE_TRANSITION","description":"The cell cycle process by which a cell in G2 phase commits to M phase."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYTOKINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYTOKINE_SECRETION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cytokines from a cell."} {"geneset":"GO_VITAMIN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VITAMIN_TRANSPORT","description":"The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."} {"geneset":"GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway."} {"geneset":"GO_BLASTODERM_SEGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLASTODERM_SEGMENTATION","description":"The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo."} {"geneset":"GO_NATURAL_KILLER_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NATURAL_KILLER_CELL_ACTIVATION","description":"The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BINDING","description":"Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."} {"geneset":"GO_POSITIVE_REGULATION_BY_HOST_OF_VIRAL_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_BY_HOST_OF_VIRAL_PROCESS","description":"A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS","description":"Any process that activates, maintains or increases the rate of a response to an extracellular stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL","description":"Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."} {"geneset":"GO_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of smoothened signaling."} {"geneset":"GO_RETINA_LAYER_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINA_LAYER_FORMATION","description":"The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia."} {"geneset":"GO_EPIDERMIS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPIDERMIS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ZINC_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ZINC_ION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus."} {"geneset":"GO_REGULATION_OF_GASTRULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GASTRULATION","description":"Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals."} {"geneset":"GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays."} {"geneset":"GO_ACTIN_MEDIATED_CELL_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_MEDIATED_CELL_CONTRACTION","description":"The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body."} {"geneset":"GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_NEUTRAL_LIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUTRAL_LIPID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity."} {"geneset":"GO_CELLULAR_RESPONSE_TO_NUTRIENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_NUTRIENT","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_GLUCOSE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GLUCOSE_TRANSPORT","description":"Any process that increases the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ADENYLATE_CYCLASE_ACTIVATING_DOPAMINE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADENYLATE_CYCLASE_ACTIVATING_DOPAMINE_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP)."} {"geneset":"GO_REGULATION_OF_DIGESTIVE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DIGESTIVE_SYSTEM_PROCESS","description":"Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."} {"geneset":"GO_REGULATION_OF_PLASMA_MEMBRANE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PLASMA_MEMBRANE_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of plasma membrane organization."} {"geneset":"GO_RESPONSE_TO_AMINO_ACID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_AMINO_ACID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups."} {"geneset":"GO_DETECTION_OF_BIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_BIOTIC_STIMULUS","description":"The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal."} {"geneset":"GO_RESPONSE_TO_VITAMIN_A","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_VITAMIN_A","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the regulated release of immunoglobulins from a cell."} {"geneset":"GO_SARCOPLASMIC_RETICULUM_CALCIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SARCOPLASMIC_RETICULUM_CALCIUM_ION_TRANSPORT","description":"The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum."} {"geneset":"GO_VENTRICULAR_SEPTUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRICULAR_SEPTUM_DEVELOPMENT","description":"The progression of the ventricular septum over time from its formation to the mature structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION","description":"Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation."} {"geneset":"GO_INSULIN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INSULIN_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of the insulin receptor binding to insulin."} {"geneset":"GO_VIRION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VIRION_ASSEMBLY","description":"A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed."} {"geneset":"GO_LIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids."} {"geneset":"GO_REGULATION_OF_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_LOCALIZATION","description":"Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location."} {"geneset":"GO_GLYCEROPHOSPHOLIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCEROPHOSPHOLIPID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate."} {"geneset":"GO_KERATAN_SULFATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KERATAN_SULFATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CIRCADIAN_RHYTHM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CIRCADIAN_RHYTHM","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior."} {"geneset":"GO_POSITIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids."} {"geneset":"GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","description":"An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein."} {"geneset":"GO_BLOOD_VESSEL_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLOOD_VESSEL_REMODELING","description":"The reorganization or renovation of existing blood vessels."} {"geneset":"GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN","description":"Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat3 protein."} {"geneset":"GO_TRIGLYCERIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRIGLYCERIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol."} {"geneset":"GO_REGULATION_OF_SKELETAL_MUSCLE_ADAPTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SKELETAL_MUSCLE_ADAPTATION","description":"Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."} {"geneset":"GO_GLIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLIAL_CELL_MIGRATION","description":"The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system."} {"geneset":"GO_MODULATION_BY_VIRUS_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODULATION_BY_VIRUS_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY","description":"The process in which a virus effects a change in the structure or processes of its host organism."} {"geneset":"GO_PROTEIN_K48_LINKED_DEUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_K48_LINKED_DEUBIQUITINATION","description":"A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein."} {"geneset":"GO_RNA_SECONDARY_STRUCTURE_UNWINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_SECONDARY_STRUCTURE_UNWINDING","description":"The process in which a secondary structure of RNA are broken or 'melted'."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_CALCIUM_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_CALCIUM_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING","description":"Any process that activates or increases the frequency, rate or extent of response to wounding."} {"geneset":"GO_STEROID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."} {"geneset":"GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell."} {"geneset":"GO_REGULATION_OF_ANION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANION_TRANSMEMBRANE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of anion transmembrane transport."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process."} {"geneset":"GO_TOXIN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOXIN_TRANSPORT","description":"The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_DETECTION_OF_LIGHT_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_LIGHT_STIMULUS","description":"The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal."} {"geneset":"GO_REGULATION_OF_HISTONE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HISTONE_PHOSPHORYLATION","description":"Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein."} {"geneset":"GO_REGULATION_OF_PROTEIN_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_IMPORT","description":"Any process that modulates the frequency, rate or extent of protein import."} {"geneset":"GO_NEUROLOGICAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROLOGICAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE","description":"The regulation of blood pressure mediated by detection of stimuli and a neurological response."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS","description":"Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DEPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DEPHOSPHORYLATION","description":"Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule."} {"geneset":"GO_DRUG_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DRUG_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice."} {"geneset":"GO_CELLULAR_RESPONSE_TO_CYTOKINE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_CYTOKINE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus."} {"geneset":"GO_FAT_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FAT_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat."} {"geneset":"GO_RESPONSE_TO_ABIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ABIOTIC_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus."} {"geneset":"GO_AMELOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMELOGENESIS","description":"The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage."} {"geneset":"GO_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus."} {"geneset":"GO_RESPONSE_TO_PROGESTERONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PROGESTERONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus."} {"geneset":"GO_REGULATION_OF_PROTON_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTON_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_NEURON_PROJECTION_REGENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEURON_PROJECTION_REGENERATION","description":"Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production."} {"geneset":"GO_POSITIVE_REGULATION_OF_SMAD_PROTEIN_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SMAD_PROTEIN_IMPORT_INTO_NUCLEUS","description":"Any process that increases the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways."} {"geneset":"GO_GENE_SILENCING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GENE_SILENCING","description":"Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction."} {"geneset":"GO_LEUKOCYTE_ADHESION_TO_VASCULAR_ENDOTHELIAL_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_ADHESION_TO_VASCULAR_ENDOTHELIAL_CELL","description":"The attachment of a leukocyte to vascular endothelial cell via adhesion molecules."} {"geneset":"GO_ZINC_II_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ZINC_II_ION_TRANSPORT","description":"The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_INTERLEUKIN_1_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERLEUKIN_1_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION","description":"Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration."} {"geneset":"GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","description":"An action potential that occurs in a ventricular cardiac muscle cell."} {"geneset":"GO_RESPONSE_TO_FATTY_ACID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_FATTY_ACID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus."} {"geneset":"GO_DNA_METHYLATION_INVOLVED_IN_GAMETE_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_METHYLATION_INVOLVED_IN_GAMETE_GENERATION","description":"The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete."} {"geneset":"GO_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."} {"geneset":"GO_EPITHELIAL_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_APOPTOTIC_PROCESS","description":"Any apoptotic process in an epithelial cell."} {"geneset":"GO_DNA_SYNTHESIS_INVOLVED_IN_DNA_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_SYNTHESIS_INVOLVED_IN_DNA_REPAIR","description":"Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template."} {"geneset":"GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube."} {"geneset":"GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_PLASMA_MEMBRANE","description":"The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins."} {"geneset":"GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_DRUG_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DRUG_TRANSPORT","description":"The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GROWTH","description":"Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."} {"geneset":"GO_TISSUE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TISSUE_REMODELING","description":"The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling."} {"geneset":"GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of cytoplasmic transport."} {"geneset":"GO_CD4_POSITIVE_OR_CD8_POSITIVE_ALPHA_BETA_T_CELL_LINEAGE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CD4_POSITIVE_OR_CD8_POSITIVE_ALPHA_BETA_T_CELL_LINEAGE_COMMITMENT","description":"The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells."} {"geneset":"GO_SEGMENT_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEGMENT_SPECIFICATION","description":"The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes."} {"geneset":"GO_CELLULAR_RESPONSE_TO_STEROL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_STEROL","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus."} {"geneset":"GO_T_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_MIGRATION","description":"The movement of a T cell within or between different tissues and organs of the body."} {"geneset":"GO_OSSIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OSSIFICATION","description":"The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance."} {"geneset":"GO_MULTI_MULTICELLULAR_ORGANISM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTI_MULTICELLULAR_ORGANISM_PROCESS","description":"A multicellular organism process which involves another multicellular organism of the same or different species."} {"geneset":"GO_REGULATION_OF_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOCYTOSIS","description":"Any process that modulates the frequency, rate or extent of endocytosis."} {"geneset":"GO_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of epidermal cell differentiation."} {"geneset":"GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY","description":"Any process involved in the carrying out of an immune response by a myeloid leukocyte."} {"geneset":"GO_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTION_POTENTIAL","description":"A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities."} {"geneset":"GO_GOLGI_TO_VACUOLE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_TO_VACUOLE_TRANSPORT","description":"The directed movement of substances from the Golgi to the vacuole."} {"geneset":"GO_IMMUNOGLOBULIN_PRODUCTION_INVOLVED_IN_IMMUNOGLOBULIN_MEDIATED_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNOGLOBULIN_PRODUCTION_INVOLVED_IN_IMMUNOGLOBULIN_MEDIATED_IMMUNE_RESPONSE","description":"The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels."} {"geneset":"GO_NEGATIVE_T_CELL_SELECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_T_CELL_SELECTION","description":"The process of elimination of immature T cells which react strongly with self-antigens."} {"geneset":"GO_LIPOPROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOPROTEIN_LOCALIZATION","description":"Any process in which a lipoprotein is transported to, or maintained in, a specific location."} {"geneset":"GO_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines."} {"geneset":"GO_NEGATIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling."} {"geneset":"GO_DETECTION_OF_VISIBLE_LIGHT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_VISIBLE_LIGHT","description":"The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm."} {"geneset":"GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION","description":"Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region."} {"geneset":"GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY","description":"A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability."} {"geneset":"GO_HISTONE_H3_K4_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H3_K4_METHYLATION","description":"The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone."} {"geneset":"GO_NEGATIVE_REGULATION_OF_BLOOD_PRESSURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_BLOOD_PRESSURE","description":"Any process in which the force of blood traveling through the circulatory system is decreased."} {"geneset":"GO_ALCOHOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALCOHOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production."} {"geneset":"GO_CELL_SUBSTRATE_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_SUBSTRATE_JUNCTION_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate."} {"geneset":"GO_MONOSACCHARIDE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOSACCHARIDE_TRANSPORT","description":"The directed movement of monosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."} {"geneset":"GO_REGULATION_OF_B_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_B_CELL_ACTIVATION","description":"Any process that modulates the frequency, rate or extent of B cell activation."} {"geneset":"GO_REGULATION_OF_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS","description":"Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus."} {"geneset":"GO_REGULATION_OF_STEROL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STEROL_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION","description":"Any process that activates or increases the frequency, rate or extent of intracellular signal transduction."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GROWTH","description":"Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION","description":"Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."} {"geneset":"GO_REGULATION_OF_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYSTEM_PROCESS","description":"Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system."} {"geneset":"GO_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION","description":"Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings."} {"geneset":"GO_REGULATION_OF_CARBOHYDRATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARBOHYDRATE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates."} {"geneset":"GO_RESPONSE_TO_BMP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_BMP","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus."} {"geneset":"GO_IMIDAZOLE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMIDAZOLE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton."} {"geneset":"GO_RESPONSE_TO_PH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PH","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution."} {"geneset":"GO_SMALL_MOLECULE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMALL_MOLECULE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule."} {"geneset":"GO_OXALATE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXALATE_TRANSPORT","description":"The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals."} {"geneset":"GO_CELLULAR_RESPONSE_TO_EXOGENOUS_DSRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_EXOGENOUS_DSRNA","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus."} {"geneset":"GO_RESPONSE_TO_TEMPERATURE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_TEMPERATURE_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus."} {"geneset":"GO_REGULATION_OF_TOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TOR_SIGNALING","description":"Any process that modulates the frequency, rate or extent of TOR signaling."} {"geneset":"GO_DNA_REPLICATION_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_REPLICATION_CHECKPOINT","description":"A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome."} {"geneset":"GO_RESPONSE_TO_ACETYLCHOLINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ACETYLCHOLINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus."} {"geneset":"GO_CELLULAR_MODIFIED_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_MODIFIED_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents."} {"geneset":"GO_REGULATION_OF_ISOTYPE_SWITCHING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ISOTYPE_SWITCHING","description":"Any process that modulates the frequency, rate or extent of isotype switching."} {"geneset":"GO_CELLULAR_GLUCOSE_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_GLUCOSE_HOMEOSTASIS","description":"A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment."} {"geneset":"GO_HEAD_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEAD_DEVELOPMENT","description":"The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body."} {"geneset":"GO_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation."} {"geneset":"GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor."} {"geneset":"GO_CYCLIC_NUCLEOTIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIC_NUCLEOTIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."} {"geneset":"GO_REGULATION_OF_APPETITE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_APPETITE","description":"Any process which modulates appetite, the desire or physical craving for food."} {"geneset":"GO_PROTEIN_DEGLYCOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DEGLYCOSYLATION","description":"The removal of sugar residues from a glycosylated protein."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta."} {"geneset":"GO_REGULATION_OF_PHOSPHOLIPASE_A2_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHOLIPASE_A2_ACTIVITY","description":"Any process that modulates the activity of the enzyme phospholipase A2."} {"geneset":"GO_RESPONSE_TO_VITAMIN_D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_VITAMIN_D","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus."} {"geneset":"GO_TRANSLATIONAL_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATIONAL_ELONGATION","description":"The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis."} {"geneset":"GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION","description":"Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules."} {"geneset":"GO_CYTOKINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_SECRETION","description":"The regulated release of cytokines from a cell. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity."} {"geneset":"GO_POSITIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered."} {"geneset":"GO_LYMPHOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_CHEMOTAXIS","description":"The directed movement of a lymphocyte in response to an external stimulus."} {"geneset":"GO_MESODERMAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESODERMAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell."} {"geneset":"GO_METANEPHRIC_MESENCHYME_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METANEPHRIC_MESENCHYME_DEVELOPMENT","description":"The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros."} {"geneset":"GO_BENZENE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BENZENE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives."} {"geneset":"GO_AUDITORY_RECEPTOR_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AUDITORY_RECEPTOR_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."} {"geneset":"GO_REGULATION_OF_ACROSOME_REACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACROSOME_REACTION","description":"Any process that modulates the frequency, rate or extent of the acrosome reaction."} {"geneset":"GO_NEURONAL_STEM_CELL_POPULATION_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURONAL_STEM_CELL_POPULATION_MAINTENANCE","description":"Any process in by an organism or tissue maintains a population of neuronal stem cells."} {"geneset":"GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of organic cyclic compound."} {"geneset":"GO_ACTIN_FILAMENT_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT_POLYMERIZATION","description":"Assembly of actin filaments by the addition of actin monomers to a filament."} {"geneset":"GO_SMOOTH_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMOOTH_MUSCLE_CONTRACTION","description":"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length."} {"geneset":"GO_MACROPHAGE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROPHAGE_CHEMOTAXIS","description":"The movement of a macrophage in response to an external stimulus."} {"geneset":"GO_NEUTRAL_LIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUTRAL_LIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_4_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_4_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-4 production."} {"geneset":"GO_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM","description":"Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism."} {"geneset":"GO_RESPONSE_TO_LIPOPROTEIN_PARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_LIPOPROTEIN_PARTICLE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus."} {"geneset":"GO_AMINO_ACID_BETAINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_ACID_BETAINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid."} {"geneset":"GO_ALPHA_BETA_T_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALPHA_BETA_T_CELL_ACTIVATION","description":"The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."} {"geneset":"GO_RIBONUCLEOPROTEIN_COMPLEX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOPROTEIN_COMPLEX_DISASSEMBLY","description":"The disaggregation of a protein-RNA complex into its constituent components."} {"geneset":"GO_CELL_SUBSTRATE_ADHERENS_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_SUBSTRATE_ADHERENS_JUNCTION_ASSEMBLY","description":"The aggregation, arrangement, and bonding together of a set of components to form a cell-substrate adherens junction."} {"geneset":"GO_ENTEROENDOCRINE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENTEROENDOCRINE_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system."} {"geneset":"GO_REGULATION_OF_JNK_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_JNK_CASCADE","description":"Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade."} {"geneset":"GO_CELLULAR_ALDEHYDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_ALDEHYDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells."} {"geneset":"GO_RHYTHMIC_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RHYTHMIC_BEHAVIOR","description":"The specific behavior of an organism that recur with measured regularity."} {"geneset":"GO_DEVELOPMENTAL_PIGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENTAL_PIGMENTATION","description":"The developmental process that results in the deposition of coloring matter in an organism, tissue or cell."} {"geneset":"GO_ARGININE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARGININE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid."} {"geneset":"GO_ACIDIC_AMINO_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACIDIC_AMINO_ACID_TRANSPORT","description":"The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_NON_RECOMBINATIONAL_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NON_RECOMBINATIONAL_REPAIR","description":"A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous region of DNA."} {"geneset":"GO_CARBOHYDRATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule."} {"geneset":"GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles."} {"geneset":"GO_OLFACTORY_LOBE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLFACTORY_LOBE_DEVELOPMENT","description":"The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell."} {"geneset":"GO_RESPONSE_TO_INTERLEUKIN_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INTERLEUKIN_6","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus."} {"geneset":"GO_VASCULOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASCULOGENESIS","description":"The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes."} {"geneset":"GO_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system."} {"geneset":"GO_REGULATION_OF_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CELL_ADHESION","description":"Any process that modulates the frequency, rate or extent of attachment of a cell to another cell."} {"geneset":"GO_BRANCHING_INVOLVED_IN_LABYRINTHINE_LAYER_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRANCHING_INVOLVED_IN_LABYRINTHINE_LAYER_MORPHOGENESIS","description":"The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer."} {"geneset":"GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation."} {"geneset":"GO_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNE_RESPONSE","description":"Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat."} {"geneset":"GO_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY","description":"Any process that modulates the frequency, rate, or extent of T cell mediated immunity."} {"geneset":"GO_POSITIVE_REGULATION_OF_CAMP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CAMP_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."} {"geneset":"GO_MECHANORECEPTOR_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MECHANORECEPTOR_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system."} {"geneset":"GO_HISTONE_UBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_UBIQUITINATION","description":"The modification of histones by addition of ubiquitin groups."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ANTIBIOTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ANTIBIOTIC","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LYASE_ACTIVITY","description":"Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."} {"geneset":"GO_NEURON_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_APOPTOTIC_PROCESS","description":"Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system."} {"geneset":"GO_REGULATION_OF_VASOCONSTRICTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VASOCONSTRICTION","description":"Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels."} {"geneset":"GO_CELLULAR_RESPONSE_TO_FATTY_ACID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_FATTY_ACID","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus."} {"geneset":"GO_MONOVALENT_INORGANIC_ANION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOVALENT_INORGANIC_ANION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell."} {"geneset":"GO_REGULATION_OF_PH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PH","description":"Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell."} {"geneset":"GO_CYCLOOXYGENASE_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLOOXYGENASE_PATHWAY","description":"The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2."} {"geneset":"GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed."} {"geneset":"GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING","description":"Any cell surface receptor signaling pathway that is involved in cell-cell signaling."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS","description":"Any process that increases the rate, frequency, or extent of a response to cytokine stimulus."} {"geneset":"GO_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."} {"geneset":"GO_GRANULOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GRANULOCYTE_DIFFERENTIATION","description":"The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils."} {"geneset":"GO_GOLGI_RIBBON_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_RIBBON_FORMATION","description":"The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE","description":"Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response."} {"geneset":"GO_DEOXYRIBONUCLEOTIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEOXYRIBONUCLEOTIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_GOLGI_APPARATUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_GOLGI_APPARATUS","description":"A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus."} {"geneset":"GO__DE_NOVO_POSTTRANSLATIONAL_PROTEIN_FOLDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO__DE_NOVO_POSTTRANSLATIONAL_PROTEIN_FOLDING","description":"The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY","description":"Any process that activates or increases the frequency, rate or extent of protein complex assembly."} {"geneset":"GO_PERK_MEDIATED_UNFOLDED_PROTEIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERK_MEDIATED_UNFOLDED_PROTEIN_RESPONSE","description":"A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity."} {"geneset":"GO_RESPONSE_TO_CORTICOSTERONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_CORTICOSTERONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses."} {"geneset":"GO_REGULATION_OF_VIRAL_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VIRAL_TRANSCRIPTION","description":"Any process that modulates the frequency, rate or extent of the transcription of the viral genome."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway."} {"geneset":"GO_TUBE_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TUBE_FORMATION","description":"Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow."} {"geneset":"GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus."} {"geneset":"GO_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS","description":"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex."} {"geneset":"GO_MEIOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEIOTIC_CELL_CYCLE","description":"Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions."} {"geneset":"GO_POSITIVE_REGULATION_OF_RENAL_SODIUM_EXCRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RENAL_SODIUM_EXCRETION","description":"Any process that increases the amount of sodium excreted in urine over a unit of time."} {"geneset":"GO_RESPONSE_TO_STIMULUS_INVOLVED_IN_REGULATION_OF_MUSCLE_ADAPTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_STIMULUS_INVOLVED_IN_REGULATION_OF_MUSCLE_ADAPTATION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation."} {"geneset":"GO_CELL_FATE_DETERMINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_FATE_DETERMINATION","description":"A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."} {"geneset":"GO_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION_OF_SOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION_OF_SOUND","description":"The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal."} {"geneset":"GO_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of osteoblast differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE","description":"Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."} {"geneset":"GO_POSITIVE_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity."} {"geneset":"GO_MRNA_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_TRANSCRIPTION","description":"The cellular synthesis of messenger RNA (mRNA) from a DNA template."} {"geneset":"GO_COENZYME_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COENZYME_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed."} {"geneset":"GO_CELLULAR_LIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_LIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving lipids, as carried out by individual cells."} {"geneset":"GO_GDP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GDP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate."} {"geneset":"GO_REGULATION_OF_PROTEIN_HOMOOLIGOMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_HOMOOLIGOMERIZATION","description":"Any process that modulates the frequency, rate or extent of protein homooligomerization."} {"geneset":"GO_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils."} {"geneset":"GO_POTASSIUM_ION_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POTASSIUM_ION_IMPORT","description":"The directed movement of potassium ions into a cell or organelle."} {"geneset":"GO_POSTTRANSCRIPTIONAL_GENE_SILENCING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSTTRANSCRIPTIONAL_GENE_SILENCING","description":"The inactivation of gene expression by a posttranscriptional mechanism."} {"geneset":"GO_CELLULAR_RESPONSE_TO_DSRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_DSRNA","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus."} {"geneset":"GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS","description":"Any process in which an organism has an effect on an organism of a different species."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma."} {"geneset":"GO_LAMELLIPODIUM_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAMELLIPODIUM_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments."} {"geneset":"GO_ADENYLATE_CYCLASE_MODULATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADENYLATE_CYCLASE_MODULATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP)."} {"geneset":"GO_PROTEIN_TARGETING_TO_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TARGETING_TO_PLASMA_MEMBRANE","description":"The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein."} {"geneset":"GO_REGULATION_OF_DNA_DAMAGE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_DAMAGE_CHECKPOINT","description":"Any process that modulates the frequency, rate or extent of a DNA damage checkpoint."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LIPID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LIPID_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION","description":"A cardiac conduction process that modulates the frequency or rate of heart contraction."} {"geneset":"GO_KETONE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KETONE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."} {"geneset":"GO_I_KAPPAB_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_I_KAPPAB_PHOSPHORYLATION","description":"The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription."} {"geneset":"GO_POSITIVE_REGULATION_OF_MRNA_3_END_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MRNA_3_END_PROCESSING","description":"Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing."} {"geneset":"GO_GROOMING_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GROOMING_BEHAVIOR","description":"The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites."} {"geneset":"GO_REGULATION_OF_HISTONE_H3_K4_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HISTONE_H3_K4_METHYLATION","description":"Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3."} {"geneset":"GO_GLUCOSE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOSE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides."} {"geneset":"GO_POSITIVE_REGULATION_OF_BLOOD_PRESSURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BLOOD_PRESSURE","description":"Any process in which the force of blood traveling through the circulatory system is increased."} {"geneset":"GO_REGULATION_OF_ANOIKIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANOIKIS","description":"Any process that modulates the frequency, rate or extent of anoikis."} {"geneset":"GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION","description":"Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_B_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_B_CELL_PROLIFERATION","description":"Any process that stops, prevents or reduces the rate or extent of B cell proliferation."} {"geneset":"GO_PURINE_NUCLEOBASE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_NUCLEOBASE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine."} {"geneset":"GO_MITOCHONDRIAL_CALCIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_CALCIUM_ION_TRANSPORT","description":"The directed movement of calcium ions (Ca2+) into, out of or within a mitochondrion."} {"geneset":"GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_INTERCONVERSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_INTERCONVERSION","description":"The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule."} {"geneset":"GO_MITOCHONDRIAL_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_FUSION","description":"Merging of two or more mitochondria within a cell to form a single compartment."} {"geneset":"GO_REGULATION_OF_DEPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEPHOSPHORYLATION","description":"Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule."} {"geneset":"GO_CARBOHYDRATE_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_HOMEOSTASIS","description":"A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell."} {"geneset":"GO_NEURON_PROJECTION_REGENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_REGENERATION","description":"The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage."} {"geneset":"GO_CARTILAGE_DEVELOPMENT_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARTILAGE_DEVELOPMENT_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS","description":"The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation."} {"geneset":"GO_LONG_TERM_SYNAPTIC_POTENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LONG_TERM_SYNAPTIC_POTENTIATION","description":"A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse."} {"geneset":"GO_MONOCARBOXYLIC_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOCARBOXYLIC_ACID_TRANSPORT","description":"The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."} {"geneset":"GO_SEX_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEX_DIFFERENTIATION","description":"The establishment of the sex of an organism by physical differentiation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HORMONE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HORMONE_SECRETION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell."} {"geneset":"GO_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CYCLE","description":"The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division."} {"geneset":"GO_CELLULAR_RESPONSE_TO_PH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_PH","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution."} {"geneset":"GO_DSRNA_FRAGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DSRNA_FRAGMENTATION","description":"Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CATECHOLAMINE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CATECHOLAMINE_SECRETION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine."} {"geneset":"GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE","description":"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."} {"geneset":"GO_RESPONSE_TO_VITAMIN_E","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_VITAMIN_E","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING","description":"Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B."} {"geneset":"GO_LYMPH_VESSEL_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPH_VESSEL_MORPHOGENESIS","description":"The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph."} {"geneset":"GO_POSITIVE_REGULATION_OF_CALCIUM_ION_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CALCIUM_ION_IMPORT","description":"Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."} {"geneset":"GO_NUCLEAR_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_IMPORT","description":"The directed movement of substances into the nucleus."} {"geneset":"GO_DETECTION_OF_ABIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_ABIOTIC_STIMULUS","description":"The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal."} {"geneset":"GO_OLIGOSACCHARIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLIGOSACCHARIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."} {"geneset":"GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL","description":"An action potential that occurs in a cardiac muscle cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle G2/M phase transition."} {"geneset":"GO_PURINE_NUCLEOSIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_NUCLEOSIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."} {"geneset":"GO_RESPONSE_TO_MUSCLE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MUSCLE_ACTIVITY","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_JNK_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_JNK_CASCADE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade."} {"geneset":"GO_REGULATION_OF_MYOTUBE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MYOTUBE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."} {"geneset":"GO_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS","description":"Any process that modulates the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus."} {"geneset":"GO_FUSION_OF_SPERM_TO_EGG_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FUSION_OF_SPERM_TO_EGG_PLASMA_MEMBRANE","description":"The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head."} {"geneset":"GO_TRACHEA_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRACHEA_MORPHOGENESIS","description":"The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS","description":"Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus."} {"geneset":"GO_ENDOTHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOTHELIAL_CELL_PROLIFERATION","description":"The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium."} {"geneset":"GO_LIPID_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_PHOSPHORYLATION","description":"The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents."} {"geneset":"GO_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells."} {"geneset":"GO_NUCLEOSIDE_PHOSPHATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_PHOSPHATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate."} {"geneset":"GO_CELLULAR_RESPONSE_TO_STARVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_STARVATION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment."} {"geneset":"GO_VESICLE_MEDIATED_TRANSPORT_BETWEEN_ENDOSOMAL_COMPARTMENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_MEDIATED_TRANSPORT_BETWEEN_ENDOSOMAL_COMPARTMENTS","description":"A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome."} {"geneset":"GO_RESPONSE_TO_DRUG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_DRUG","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease."} {"geneset":"GO_LIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."} {"geneset":"GO_AMMONIUM_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMMONIUM_TRANSPORT","description":"The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals."} {"geneset":"GO_PHOTORECEPTOR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_CELL_DIFFERENTIATION","description":"The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster."} {"geneset":"GO_ORGANONITROGEN_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANONITROGEN_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving organonitrogen compound."} {"geneset":"GO_MEGAKARYOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEGAKARYOCYTE_DIFFERENTIATION","description":"The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte."} {"geneset":"GO_PROTEIN_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DEPOLYMERIZATION","description":"The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein."} {"geneset":"GO_CELLULAR_RESPONSE_TO_CALCIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_CALCIUM_ION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus."} {"geneset":"GO_DNA_METHYLATION_OR_DEMETHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_METHYLATION_OR_DEMETHYLATION","description":"The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."} {"geneset":"GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY","description":"Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."} {"geneset":"GO_GLOMERULAR_EPITHELIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLOMERULAR_EPITHELIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \\feet\\ that interdigitate with the \\feet\\ of other glomerular epithelial cells in the metanephros."} {"geneset":"GO_MITOTIC_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_RECOMBINATION","description":"The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles."} {"geneset":"GO_STRAND_DISPLACEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRAND_DISPLACEMENT","description":"The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules."} {"geneset":"GO_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity."} {"geneset":"GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT","description":"Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."} {"geneset":"GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow."} {"geneset":"GO_PIRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIRNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GLUCOSE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GLUCOSE_TRANSPORT","description":"Any process that decreases the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_VACUOLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole."} {"geneset":"GO_CARDIOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIOCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual."} {"geneset":"GO_RESPONSE_TO_GROWTH_FACTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_GROWTH_FACTOR","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_WOUND_HEALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_WOUND_HEALING","description":"Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury."} {"geneset":"GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY","description":"Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELLULAR_SENESCENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELLULAR_SENESCENCE","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence."} {"geneset":"GO_POSITIVE_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION","description":"Any process that activates or increases the rate or extent of activated T cell proliferation."} {"geneset":"GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ER","description":"The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition."} {"geneset":"GO_DIENCEPHALON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIENCEPHALON_DEVELOPMENT","description":"The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex."} {"geneset":"GO_POSITIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."} {"geneset":"GO_MITOCHONDRION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRION_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components."} {"geneset":"GO_HAIR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HAIR_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a hair cell."} {"geneset":"GO_REGULATION_OF_STEM_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STEM_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."} {"geneset":"GO_REGULATION_OF_CHROMATIN_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHROMATIN_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of chromatin organization."} {"geneset":"GO_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS","description":"The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)."} {"geneset":"GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_POTENTIAL","description":"Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."} {"geneset":"GO_PERICARDIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERICARDIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery."} {"geneset":"GO_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_FATE_COMMITMENT","description":"The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."} {"geneset":"GO_PEROXISOMAL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEROXISOMAL_TRANSPORT","description":"Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."} {"geneset":"GO_POSITIVE_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of adherens junction organization."} {"geneset":"GO_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION","description":"Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."} {"geneset":"GO_REGULATION_OF_MYOBLAST_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MYOBLAST_FUSION","description":"Any process that modulates the frequency, rate or extent of myoblast fusion."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY","description":"Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds."} {"geneset":"GO_REGULATION_OF_NEUROTRANSMITTER_UPTAKE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUROTRANSMITTER_UPTAKE","description":"Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."} {"geneset":"GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_ACETYLATION","description":"Any process that activates or increases the frequency, rate or extent of protein acetylation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS","description":"A biological process that directly contributes to the process of producing new individuals, involving another organism."} {"geneset":"GO_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT","description":"The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure."} {"geneset":"GO_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS","description":"Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism."} {"geneset":"GO_DETECTION_OF_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_STIMULUS","description":"The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal."} {"geneset":"GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_VACUOLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_VACUOLE","description":"The directed movement of a protein to a specific location in a vacuole."} {"geneset":"GO_FUCOSE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FUCOSE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose."} {"geneset":"GO_REGULATION_OF_AMINO_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_AMINO_ACID_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_APOPTOTIC_DNA_FRAGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APOPTOTIC_DNA_FRAGMENTATION","description":"The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments."} {"geneset":"GO_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES","description":"The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LIPID_STORAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LIPID_STORAGE","description":"Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."} {"geneset":"GO_REGULATION_OF_MICROVILLUS_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MICROVILLUS_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus."} {"geneset":"GO_SCF_DEPENDENT_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SCF_DEPENDENT_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."} {"geneset":"GO_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS","description":"Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis."} {"geneset":"GO_ENTERIC_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENTERIC_NERVOUS_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation."} {"geneset":"GO_MUSCLE_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_CELL_FATE_COMMITMENT","description":"The process in which the cellular identity of muscle cells is acquired and determined."} {"geneset":"GO_PERIPHERAL_NERVOUS_SYSTEM_AXON_ENSHEATHMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERIPHERAL_NERVOUS_SYSTEM_AXON_ENSHEATHMENT","description":"The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction."} {"geneset":"GO_IRON_ION_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IRON_ION_IMPORT","description":"The directed movement of iron ions into a cell or organelle."} {"geneset":"GO_REGULATION_OF_METANEPHROS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_METANEPHROS_DEVELOPMENT","description":"Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING","description":"Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length."} {"geneset":"GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups."} {"geneset":"GO_DNA_GEOMETRIC_CHANGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_GEOMETRIC_CHANGE","description":"The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases."} {"geneset":"GO_REGULATION_OF_GUANYLATE_CYCLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GUANYLATE_CYCLASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of guanylate cyclase activity."} {"geneset":"GO_REGULATION_OF_MONOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MONOCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of monocyte differentiation."} {"geneset":"GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_INCISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_INCISION","description":"A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound."} {"geneset":"GO_CERAMIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CERAMIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving ceramides, any N-acylated sphingoid."} {"geneset":"GO_REGULATION_OF_LAMELLIPODIUM_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LAMELLIPODIUM_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of lamellipodium organization."} {"geneset":"GO_REGULATION_OF_B_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_B_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of B cell proliferation."} {"geneset":"GO_REGULATION_OF_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING","description":"Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."} {"geneset":"GO_SPINAL_CORD_ASSOCIATION_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINAL_CORD_ASSOCIATION_NEURON_DIFFERENTIATION","description":"The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate."} {"geneset":"GO_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","description":"The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels."} {"geneset":"GO_DEOXYRIBOSE_PHOSPHATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEOXYRIBOSE_PHOSPHATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."} {"geneset":"GO_HEART_VALVE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_VALVE_DEVELOPMENT","description":"The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion."} {"geneset":"GO_GLYCOSYL_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSYL_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycosyl compound."} {"geneset":"GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY","description":"Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor."} {"geneset":"GO_PEPTIDYL_TYROSINE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_TYROSINE_MODIFICATION","description":"The modification of peptidyl-tyrosine."} {"geneset":"GO_LEUKOCYTE_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_CELL_CELL_ADHESION","description":"The attachment of a leukocyte to another cell via adhesion molecules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DEGRANULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DEGRANULATION","description":"Any process that stops, prevents, or reduces the rate of leukocyte degranulation."} {"geneset":"GO_NUCLEAR_PORE_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_PORE_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_ORGANELLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_ORGANELLE","description":"A process in which a protein is transported to, or maintained in, a location within an organelle."} {"geneset":"GO_PHOSPHATIDYLETHANOLAMINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLETHANOLAMINE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine."} {"geneset":"GO_ENDOCYTIC_RECYCLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCYTIC_RECYCLING","description":"The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport."} {"geneset":"GO_CELLULAR_RESPONSE_TO_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_RADIATION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING","description":"Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_17_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_17_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."} {"geneset":"GO_POSITIVE_REGULATION_OF_DENDRITE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DENDRITE_MORPHOGENESIS","description":"Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis."} {"geneset":"GO_SUPEROXIDE_ANION_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUPEROXIDE_ANION_GENERATION","description":"The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways."} {"geneset":"GO_CELLULAR_RESPONSE_TO_KETONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_KETONE","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_17_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_17_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."} {"geneset":"GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway."} {"geneset":"GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state at the level of the multicellular organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle G1/S phase transition."} {"geneset":"GO_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway."} {"geneset":"GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","description":"Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator."} {"geneset":"GO_URONIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_URONIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose."} {"geneset":"GO_REGULATION_OF_DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION","description":"Any process that activates or increases the frequency, rate or extent of production of a cytokine."} {"geneset":"GO_RESPONSE_TO_YEAST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_YEAST","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species."} {"geneset":"GO_GAMETE_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GAMETE_GENERATION","description":"The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell."} {"geneset":"GO_KIDNEY_MESENCHYME_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KIDNEY_MESENCHYME_DEVELOPMENT","description":"The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney."} {"geneset":"GO_REPLICATIVE_SENESCENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REPLICATIVE_SENESCENCE","description":"A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging."} {"geneset":"GO_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides."} {"geneset":"GO_DENDRITIC_SPINE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITIC_SPINE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission."} {"geneset":"GO_COCHLEA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COCHLEA_DEVELOPMENT","description":"The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound."} {"geneset":"GO_HISTONE_H2A_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H2A_ACETYLATION","description":"The modification of histone H2A by the addition of an acetyl group."} {"geneset":"GO_DNA_REPLICATION_DEPENDENT_NUCLEOSOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_REPLICATION_DEPENDENT_NUCLEOSOME_ORGANIZATION","description":"The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation."} {"geneset":"GO_CELLULAR_COMPONENT_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_COMPONENT_MORPHOGENESIS","description":"The process in which cellular structures, including whole cells or cell parts, are generated and organized."} {"geneset":"GO_CELL_AGING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_AGING","description":"An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MEGAKARYOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MEGAKARYOCYTE_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation."} {"geneset":"GO_ACTIVATION_OF_MAPKKK_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_MAPKKK_ACTIVITY","description":"Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK)."} {"geneset":"GO_RRNA_3_END_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_3_END_PROCESSING","description":"Any process involved in forming the mature 3' end of an rRNA molecule."} {"geneset":"GO_GLUTATHIONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTATHIONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."} {"geneset":"GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION","description":"Any process that activates or increases the frequency, rate or extent of microtubule polymerization."} {"geneset":"GO_PYRIMIDINE_CONTAINING_COMPOUND_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_CONTAINING_COMPOUND_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of a pyrimidine-containing compound across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof."} {"geneset":"GO_BRANCHED_CHAIN_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRANCHED_CHAIN_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."} {"geneset":"GO_ENERGY_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENERGY_HOMEOSTASIS","description":"Any process involved in the balance between food intake (energy input) and energy expenditure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity."} {"geneset":"GO_DEPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEPHOSPHORYLATION","description":"The process of removing one or more phosphoric (ester or anhydride) residues from a molecule."} {"geneset":"GO_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_HEART_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_HEART_MORPHOGENESIS","description":"Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis."} {"geneset":"GO_MATERNAL_PROCESS_INVOLVED_IN_FEMALE_PREGNANCY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATERNAL_PROCESS_INVOLVED_IN_FEMALE_PREGNANCY","description":"A reproductive process occurring in the mother that allows an embryo or fetus to develop within it."} {"geneset":"GO_UBIQUINONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUINONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION","description":"Any process that activates or increases the rate or extent of cell adhesion to another cell."} {"geneset":"GO_EARLY_ENDOSOME_TO_GOLGI_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EARLY_ENDOSOME_TO_GOLGI_TRANSPORT","description":"The directed movement of substances from early endosomes to the Golgi."} {"geneset":"GO_POSITIVE_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of cation transmembrane transport."} {"geneset":"GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE","description":"The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes."} {"geneset":"GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals initiated by a ligand binding to an receptor located within a cell."} {"geneset":"GO_BEHAVIORAL_RESPONSE_TO_COCAINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BEHAVIORAL_RESPONSE_TO_COCAINE","description":"Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus."} {"geneset":"GO_HISTONE_MRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_MRNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving an mRNA encoding a histone."} {"geneset":"GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE","description":"Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane."} {"geneset":"GO_PYRIMIDINE_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."} {"geneset":"GO_RESPONSE_TO_PARATHYROID_HORMONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PARATHYROID_HORMONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus."} {"geneset":"GO_HINDBRAIN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HINDBRAIN_MORPHOGENESIS","description":"The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."} {"geneset":"GO_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response."} {"geneset":"GO_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING","description":"The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_DEPOLYMERIZATION","description":"Any process that activates or increases the frequency, rate or extent of protein depolymerization."} {"geneset":"GO_MUSCLE_HYPERTROPHY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_HYPERTROPHY","description":"The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy."} {"geneset":"GO_HUMORAL_IMMUNE_RESPONSE_MEDIATED_BY_CIRCULATING_IMMUNOGLOBULIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HUMORAL_IMMUNE_RESPONSE_MEDIATED_BY_CIRCULATING_IMMUNOGLOBULIN","description":"An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery."} {"geneset":"GO_REGULATION_OF_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids."} {"geneset":"GO_MULTICELLULAR_ORGANISMAL_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISMAL_SIGNALING","description":"The transfer of information occurring at the level of a multicellular organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS","description":"Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."} {"geneset":"GO_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION","description":"Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion."} {"geneset":"GO_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of organic hydroxy compound."} {"geneset":"GO_CDP_DIACYLGLYCEROL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CDP_DIACYLGLYCEROL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis."} {"geneset":"GO_FUCOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FUCOSYLATION","description":"The covalent attachment of a fucosyl group to an acceptor molecule."} {"geneset":"GO_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY","description":"Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor."} {"geneset":"GO_RHYTHMIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RHYTHMIC_PROCESS","description":"Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism."} {"geneset":"GO_NEUROMUSCULAR_PROCESS_CONTROLLING_POSTURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROMUSCULAR_PROCESS_CONTROLLING_POSTURE","description":"Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts."} {"geneset":"GO_MYOTUBE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOTUBE_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."} {"geneset":"GO_STEROID_HORMONE_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_HORMONE_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals mediated by a steroid hormone binding to a receptor."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS","description":"Any process that modulates the frequency, rate, or extent of a response to biotic stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_SIZE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_SIZE","description":"Any process that increases cell size."} {"geneset":"GO_DETECTION_OF_LIGHT_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_LIGHT_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION","description":"The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_CELL_SURFACE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_CELL_SURFACE","description":"A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_8_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_8_SECRETION","description":"Any process that modulates the frequency, rate or extent of interleukin-8 secretion."} {"geneset":"GO_REGULATION_OF_SUPEROXIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SUPEROXIDE_METABOLIC_PROCESS","description":"Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species."} {"geneset":"GO_PEPTIDYL_PROLINE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_PROLINE_MODIFICATION","description":"The modification of peptidyl-proline."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEURON_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEURON_MIGRATION","description":"Any process that activates or increases the frequency, rate or extent of neuron migration."} {"geneset":"GO_REGULATION_OF_LONG_TERM_NEURONAL_SYNAPTIC_PLASTICITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LONG_TERM_NEURONAL_SYNAPTIC_PLASTICITY","description":"A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers."} {"geneset":"GO_PHOSPHOLIPID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_TRANSPORT","description":"The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester."} {"geneset":"GO_ACROSOME_REACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACROSOME_REACTION","description":"The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida surrounding the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the egg."} {"geneset":"GO_SOMATIC_STEM_CELL_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMATIC_STEM_CELL_DIVISION","description":"The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line."} {"geneset":"GO_HISTONE_MRNA_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_MRNA_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA)."} {"geneset":"GO_ACETYL_COA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACETYL_COA_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated."} {"geneset":"GO_RESPONSE_TO_ARSENIC_CONTAINING_SUBSTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ARSENIC_CONTAINING_SUBSTANCE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides."} {"geneset":"GO_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of DNA biosynthetic process."} {"geneset":"GO_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands."} {"geneset":"GO_CARDIOLIPIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIOLIPIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol."} {"geneset":"GO_REGULATION_OF_CELL_CYCLE_ARREST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CYCLE_ARREST","description":"Any process that modulates the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases."} {"geneset":"GO_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME","description":"Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism."} {"geneset":"GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS","description":"Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis."} {"geneset":"GO_FEMALE_GAMETE_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FEMALE_GAMETE_GENERATION","description":"Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction."} {"geneset":"GO_PLASMA_MEMBRANE_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLASMA_MEMBRANE_FUSION","description":"The joining of two or more lipid bilayer membranes that surround a cell."} {"geneset":"GO_EXTRACELLULAR_MATRIX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_MATRIX_DISASSEMBLY","description":"A process that results in the breakdown of the extracellular matrix."} {"geneset":"GO_PROTEIN_HOMOOLIGOMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HOMOOLIGOMERIZATION","description":"The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."} {"geneset":"GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_CELL_DEATH","description":"Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death."} {"geneset":"GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER","description":"The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter."} {"geneset":"GO_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION","description":"Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."} {"geneset":"GO_NONMOTILE_PRIMARY_CILIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NONMOTILE_PRIMARY_CILIUM_ASSEMBLY","description":"The assembly of a primary cilium which contains a variable array of axonemal microtubules but does not contain molecular motors. Nonmotile primary cilia are found on many different cell types and function as sensory organelles that concentrate and organize sensory signaling molecules."} {"geneset":"GO_HEART_TRABECULA_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_TRABECULA_FORMATION","description":"The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod."} {"geneset":"GO_BODY_FLUID_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BODY_FLUID_SECRETION","description":"The controlled release of a fluid by a cell or tissue in an animal."} {"geneset":"GO_TOR_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOR_SIGNALING","description":"A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors."} {"geneset":"GO_MEMBRANE_HYPERPOLARIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_HYPERPOLARIZATION","description":"The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential."} {"geneset":"GO_CELLULAR_WATER_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_WATER_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of water within a cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of chromosome organization."} {"geneset":"GO_ADENYLATE_CYCLASE_INHIBITING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADENYLATE_CYCLASE_INHIBITING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP)."} {"geneset":"GO_RESPONSE_TO_VITAMIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_VITAMIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus."} {"geneset":"GO_REGULATION_OF_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ATPASE_ACTIVITY","description":"Any process that modulates the rate of ATP hydrolysis by an ATPase."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade."} {"geneset":"GO_STRIATED_MUSCLE_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRIATED_MUSCLE_CELL_PROLIFERATION","description":"The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle."} {"geneset":"GO_MUSCLE_FIBER_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_FIBER_DEVELOPMENT","description":"The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."} {"geneset":"GO_THALAMUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THALAMUS_DEVELOPMENT","description":"The process in which the thalamus changes over time, from its initial formation to its mature state."} {"geneset":"GO_STEROL_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROL_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CHEMOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CHEMOKINE_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production."} {"geneset":"GO_DETERMINATION_OF_ADULT_LIFESPAN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETERMINATION_OF_ADULT_LIFESPAN","description":"The control of viability and duration in the adult phase of the life-cycle."} {"geneset":"GO_REGULATION_OF_PROTEIN_KINASE_C_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_KINASE_C_SIGNALING","description":"Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."} {"geneset":"GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity."} {"geneset":"GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS","description":"Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."} {"geneset":"GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION","description":"Any process that activates or increases the frequency, rate or extent of epithelial cell migration."} {"geneset":"GO_MISMATCH_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MISMATCH_REPAIR","description":"A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination."} {"geneset":"GO_MACROPHAGE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROPHAGE_DIFFERENTIATION","description":"The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage."} {"geneset":"GO_PHARYNGEAL_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHARYNGEAL_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear."} {"geneset":"GO_REGULATION_OF_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY","description":"Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns."} {"geneset":"GO_MYELIN_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELIN_ASSEMBLY","description":"The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system."} {"geneset":"GO_HOMOTYPIC_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOMOTYPIC_CELL_CELL_ADHESION","description":"The attachment of a cell to a second cell of the identical type via adhesion molecules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation."} {"geneset":"GO_ERROR_PRONE_TRANSLESION_SYNTHESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERROR_PRONE_TRANSLESION_SYNTHESIS","description":"The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites."} {"geneset":"GO_MAST_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAST_CELL_MEDIATED_IMMUNITY","description":"Any process involved in the carrying out of an immune response by a mast cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_DEACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_DEACETYLATION","description":"Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic"} {"geneset":"GO_NEGATIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION","description":"Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother."} {"geneset":"GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS_WITHIN_A_TISSUE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS_WITHIN_A_TISSUE","description":"Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue."} {"geneset":"GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS","description":"Any process that activates or increases the frequency, rate, or extent of an immune effector process."} {"geneset":"GO_UROGENITAL_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UROGENITAL_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ALCOHOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ALCOHOL","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY","description":"Any process that stops or reduces the activity of a monooxygenase."} {"geneset":"GO_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION","description":"The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein."} {"geneset":"GO_CELL_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_JUNCTION_ASSEMBLY","description":"A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction."} {"geneset":"GO_LATERAL_VENTRICLE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LATERAL_VENTRICLE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle."} {"geneset":"GO_MACROMOLECULE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMOLECULE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."} {"geneset":"GO_INTERACTION_WITH_SYMBIONT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERACTION_WITH_SYMBIONT","description":"An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism."} {"geneset":"GO_REGULATION_OF_POLYSACCHARIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_POLYSACCHARIDE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides."} {"geneset":"GO_SMOOTHENED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMOOTHENED_SIGNALING_PATHWAY","description":"A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened."} {"geneset":"GO_CELL_MIGRATION_IN_HINDBRAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MIGRATION_IN_HINDBRAIN","description":"The orderly movement of a cell that will reside in the hindbrain."} {"geneset":"GO_EYE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EYE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight."} {"geneset":"GO_TRIPARTITE_REGIONAL_SUBDIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRIPARTITE_REGIONAL_SUBDIVISION","description":"Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions."} {"geneset":"GO_ORGANIC_CATION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_CATION_TRANSPORT","description":"The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage."} {"geneset":"GO_SLEEP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SLEEP","description":"Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain."} {"geneset":"GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION","description":"A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring."} {"geneset":"GO_URATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_URATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals."} {"geneset":"GO_PROTEIN_DEPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DEPHOSPHORYLATION","description":"The process of removing one or more phosphoric residues from a protein."} {"geneset":"GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of cellular protein catabolic process."} {"geneset":"GO_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION","description":"Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues."} {"geneset":"GO_REGULATION_OF_NEURON_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEURON_DEATH","description":"Any process that modulates the frequency, rate or extent of neuron death."} {"geneset":"GO_TETRAHYDROFOLATE_INTERCONVERSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TETRAHYDROFOLATE_INTERCONVERSION","description":"The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules."} {"geneset":"GO_RESPONSE_TO_GAMMA_RADIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_GAMMA_RADIATION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum."} {"geneset":"GO_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity."} {"geneset":"GO_REGULATION_OF_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_DEATH","description":"Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death."} {"geneset":"GO_REGULATION_OF_RHODOPSIN_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RHODOPSIN_MEDIATED_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STRESS_FIBER_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STRESS_FIBER_ASSEMBLY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_IMPORT","description":"Any process that activates or increases the frequency, rate or extent of protein import."} {"geneset":"GO_MULTI_ORGANISM_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTI_ORGANISM_METABOLIC_PROCESS","description":"A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism."} {"geneset":"GO_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of keratinocyte differentiation."} {"geneset":"GO_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell."} {"geneset":"GO_REGULATION_OF_BMP_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BMP_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway."} {"geneset":"GO_HEART_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_PROCESS","description":"A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."} {"geneset":"GO_MUSCLE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_SYSTEM_PROCESS","description":"A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers."} {"geneset":"GO_MESENCHYME_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESENCHYME_DEVELOPMENT","description":"The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells."} {"geneset":"GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER","description":"The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter."} {"geneset":"GO_GLIAL_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLIAL_CELL_FATE_COMMITMENT","description":"The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEOLYSIS","description":"Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."} {"geneset":"GO_REGULATION_OF_CILIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CILIUM_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of cilium assembly."} {"geneset":"GO_ACTIVATION_OF_PROTEIN_KINASE_B_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_PROTEIN_KINASE_B_ACTIVITY","description":"Any process that initiates the activity of the inactive enzyme protein kinase B."} {"geneset":"GO_REGULATION_OF_TRANSLATIONAL_INITIATION_IN_RESPONSE_TO_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSLATIONAL_INITIATION_IN_RESPONSE_TO_STRESS","description":"Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress."} {"geneset":"GO_ANTERIOR_POSTERIOR_AXIS_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTERIOR_POSTERIOR_AXIS_SPECIFICATION","description":"The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."} {"geneset":"GO_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION","description":"Any process that modulates the frequency, rate or extent of long-term synaptic potentiation."} {"geneset":"GO_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING","description":"Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B."} {"geneset":"GO_HOMOLOGOUS_CHROMOSOME_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOMOLOGOUS_CHROMOSOME_SEGREGATION","description":"The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets."} {"geneset":"GO_MUSCLE_CELL_CELLULAR_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_CELL_CELLULAR_HOMEOSTASIS","description":"The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state."} {"geneset":"GO_T_CELL_LINEAGE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_LINEAGE_COMMITMENT","description":"The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell."} {"geneset":"GO_NUCLEOSIDE_BISPHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_BISPHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."} {"geneset":"GO_RESPONSE_TO_LITHIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_LITHIUM_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus."} {"geneset":"GO_PROTEIN_FOLDING_IN_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_FOLDING_IN_ENDOPLASMIC_RETICULUM","description":"A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)."} {"geneset":"GO_REGULATION_OF_FATTY_ACID_OXIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FATTY_ACID_OXIDATION","description":"Any process that modulates the frequency, rate or extent of fatty acid oxidation."} {"geneset":"GO_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM","description":"The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis."} {"geneset":"GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS","description":"Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."} {"geneset":"GO_ENDODERM_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDODERM_FORMATION","description":"The formation of the endoderm during gastrulation."} {"geneset":"GO_POSITIVE_REGULATION_OF_SPROUTING_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SPROUTING_ANGIOGENESIS","description":"Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis."} {"geneset":"GO_REGULATION_OF_DEVELOPMENT_HETEROCHRONIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEVELOPMENT_HETEROCHRONIC","description":"Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached."} {"geneset":"GO_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER","description":"The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition."} {"geneset":"GO_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of a humoral immune response."} {"geneset":"GO_REGULATION_OF_MAP_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MAP_KINASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of MAP kinase activity."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production."} {"geneset":"GO_FEMALE_MEIOTIC_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FEMALE_MEIOTIC_DIVISION","description":"A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline."} {"geneset":"GO_REGULATION_OF_GLUTAMATE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLUTAMATE_SECRETION","description":"Any process that modulates the frequency, rate or extent of the controlled release of glutamate."} {"geneset":"GO_NLS_BEARING_PROTEIN_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NLS_BEARING_PROTEIN_IMPORT_INTO_NUCLEUS","description":"The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear membrane."} {"geneset":"GO_VACUOLE_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLE_FUSION","description":"Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole."} {"geneset":"GO_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE","description":"Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance."} {"geneset":"GO_POSITIVE_REGULATION_OF_BONE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BONE_REMODELING","description":"Any process that activates or increases the frequency, rate or extent of bone remodeling."} {"geneset":"GO_HISTONE_H3_K4_TRIMETHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H3_K4_TRIMETHYLATION","description":"The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone."} {"geneset":"GO_PRE_MIRNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRE_MIRNA_PROCESSING","description":"Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ESTROGEN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ESTROGEN_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics."} {"geneset":"GO_LYTIC_VACUOLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYTIC_VACUOLE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole."} {"geneset":"GO_REGULATION_OF_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHEMOTAXIS","description":"Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."} {"geneset":"GO_MEIOTIC_CELL_CYCLE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEIOTIC_CELL_CYCLE_PROCESS","description":"A process that is part of the meiotic cell cycle."} {"geneset":"GO_REGULATION_OF_PLATELET_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PLATELET_ACTIVATION","description":"Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization."} {"geneset":"GO_DEVELOPMENTAL_CELL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENTAL_CELL_GROWTH","description":"The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another."} {"geneset":"GO_REGULATION_OF_BONE_RESORPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BONE_RESORPTION","description":"Any process that modulates the frequency, rate or extent of bone tissue loss (resorption)."} {"geneset":"GO_SPINDLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINDLE_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."} {"geneset":"GO_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."} {"geneset":"GO_CONVERGENT_EXTENSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONVERGENT_EXTENSION","description":"The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis."} {"geneset":"GO_SPHINGOLIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPHINGOLIPID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."} {"geneset":"GO_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein."} {"geneset":"GO_REGULATION_OF_MULTI_ORGANISM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MULTI_ORGANISM_PROCESS","description":"Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species."} {"geneset":"GO_REGULATION_OF_TRANSLATIONAL_FIDELITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSLATIONAL_FIDELITY","description":"Any process that modulates the ability of the translational apparatus to interpret the genetic code."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_CYCLE_ARREST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_CYCLE_ARREST","description":"Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases."} {"geneset":"GO_CONNECTIVE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONNECTIVE_TISSUE_DEVELOPMENT","description":"The progression of a connective tissue over time, from its formation to the mature structure."} {"geneset":"GO_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells."} {"geneset":"GO_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION","description":"Any process in which a protein is transported to, or maintained in, a specific location."} {"geneset":"GO_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."} {"geneset":"GO_NUCLEAR_ENVELOPE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_ENVELOPE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope."} {"geneset":"GO_ASYMMETRIC_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASYMMETRIC_PROTEIN_LOCALIZATION","description":"Any process in which a protein is transported to, or maintained in, a specific location such that it is distributed asymmetrically."} {"geneset":"GO_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of glia cell differentiation."} {"geneset":"GO_BIOMINERAL_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BIOMINERAL_TISSUE_DEVELOPMENT","description":"Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism."} {"geneset":"GO_SCHWANN_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SCHWANN_CELL_DEVELOPMENT","description":"The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function."} {"geneset":"GO_POSITIVE_REGULATION_OF_B_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_B_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of B cell differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_HISTONE_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HISTONE_METHYLATION","description":"Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones."} {"geneset":"GO_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation."} {"geneset":"GO_RNA_POLYADENYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYADENYLATION","description":"The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule."} {"geneset":"GO_NEUROTRANSMITTER_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTRANSMITTER_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."} {"geneset":"GO_ORGANELLE_INHERITANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_INHERITANCE","description":"The partitioning of organelles between daughter cells at cell division."} {"geneset":"GO_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands."} {"geneset":"GO_ASPARTATE_FAMILY_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASPARTATE_FAMILY_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."} {"geneset":"GO_EXPLORATION_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXPLORATION_BEHAVIOR","description":"The specific behavior of an organism in response to a novel environment or stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that activates or increases the frequency, rate or extent of muscle tissue development."} {"geneset":"GO_MRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes."} {"geneset":"GO_RESPONSE_TO_THYROID_HORMONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_THYROID_HORMONE","description":"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus."} {"geneset":"GO_PROTEIN_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of a protein across a membrane by means of some agent such as a transporter or pore."} {"geneset":"GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR","description":"A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered."} {"geneset":"GO_RESPONSE_TO_RETINOIC_ACID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_RETINOIC_ACID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus."} {"geneset":"GO_MAMMARY_GLAND_LOBULE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAMMARY_GLAND_LOBULE_DEVELOPMENT","description":"The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland."} {"geneset":"GO_PARAXIAL_MESODERM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PARAXIAL_MESODERM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube."} {"geneset":"GO_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH","description":"The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel."} {"geneset":"GO_DIACYLGLYCEROL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIACYLGLYCEROL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group."} {"geneset":"GO_COCHLEA_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COCHLEA_MORPHOGENESIS","description":"The process in which the cochlea is generated and organized."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids."} {"geneset":"GO_REGULATION_OF_TRANSLATIONAL_INITIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSLATIONAL_INITIATION","description":"Any process that modulates the frequency, rate or extent of translational initiation."} {"geneset":"GO_MOTILE_CILIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MOTILE_CILIUM_ASSEMBLY","description":"The assembly of a motile cilium, a cilium that contains a regular longitudinal array of axonemal microtubules. In vertebrates, motile cilia are usually formed around a 9 + 2 microtubule core structure. Motile cilia are often found in tissues where propagation of fluid is necessary for proper organ development or function."} {"geneset":"GO_POSITIVE_REGULATION_OF_FATTY_ACID_OXIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_FATTY_ACID_OXIDATION","description":"Any process that activates or increases the frequency, rate or extent of fatty acid oxidation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation."} {"geneset":"GO_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION","description":"Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse."} {"geneset":"GO_CELL_RECOGNITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_RECOGNITION","description":"The process in which a cell in an organism interprets its surroundings."} {"geneset":"GO_REGULATION_OF_RETROGRADE_PROTEIN_TRANSPORT_ER_TO_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RETROGRADE_PROTEIN_TRANSPORT_ER_TO_CYTOSOL","description":"Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol."} {"geneset":"GO_PROTEIN_K63_LINKED_UBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_K63_LINKED_UBIQUITINATION","description":"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION","description":"Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."} {"geneset":"GO_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances."} {"geneset":"GO_MESENCHYMAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESENCHYMAL_CELL_PROLIFERATION","description":"The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."} {"geneset":"GO_LIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."} {"geneset":"GO_REVERSE_CHOLESTEROL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REVERSE_CHOLESTEROL_TRANSPORT","description":"The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism."} {"geneset":"GO_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids."} {"geneset":"GO_REGULATION_OF_CHOLESTEROL_STORAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHOLESTEROL_STORAGE","description":"Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_SYNAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_SYNAPSE","description":"Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell."} {"geneset":"GO_PROSTATE_GLAND_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROSTATE_GLAND_GROWTH","description":"The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_APOPTOTIC_PROCESS","description":"Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death."} {"geneset":"GO_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling."} {"geneset":"GO_RESPIRATORY_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPIRATORY_SYSTEM_DEVELOPMENT","description":"The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange."} {"geneset":"GO_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of ions within an organism or cell."} {"geneset":"GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION","description":"A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STAT_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STAT_CASCADE","description":"Any process that stops, prevents or reduces the frequency, rate or extent of STAT cascade."} {"geneset":"GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_GABAERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_GABAERGIC","description":"Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."} {"geneset":"GO_NUCLEOSIDE_TRIPHOSPHATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_TRIPHOSPHATE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar."} {"geneset":"GO_NEUROEPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROEPITHELIAL_CELL_DIFFERENTIATION","description":"The process in which epiblast cells acquire specialized features of neuroepithelial cells."} {"geneset":"GO_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."} {"geneset":"GO_REGULATION_OF_GLUCOSE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLUCOSE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_MATURE_B_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATURE_B_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response."} {"geneset":"GO_CATECHOLAMINE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATECHOLAMINE_TRANSPORT","description":"The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway."} {"geneset":"GO_ADHERENS_JUNCTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADHERENS_JUNCTION_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments."} {"geneset":"GO_EPITHELIAL_CELL_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_MORPHOGENESIS","description":"The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state."} {"geneset":"GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of osteoblast differentiation."} {"geneset":"GO_OSTEOBLAST_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OSTEOBLAST_DEVELOPMENT","description":"The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone."} {"geneset":"GO_MYD88_INDEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYD88_INDEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","description":"Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_RECOMBINATION","description":"Any process that activates or increases the frequency, rate or extent of DNA recombination."} {"geneset":"GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION_OF_STAT_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION_OF_STAT_PROTEIN","description":"Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."} {"geneset":"GO_HISTONE_H4_K16_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H4_K16_ACETYLATION","description":"The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone."} {"geneset":"GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION","description":"Any process that activates or increases the frequency, rate or extent of natural killer cell activation."} {"geneset":"GO_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION","description":"The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells."} {"geneset":"GO_CHRONIC_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHRONIC_INFLAMMATORY_RESPONSE","description":"Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response."} {"geneset":"GO_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY","description":"Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."} {"geneset":"GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE","description":"Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."} {"geneset":"GO_MEMBRANE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_ORGANIZATION","description":"A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins."} {"geneset":"GO_CAMP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CAMP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."} {"geneset":"GO_MITOCHONDRIAL_ATP_SYNTHESIS_COUPLED_PROTON_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_ATP_SYNTHESIS_COUPLED_PROTON_TRANSPORT","description":"The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis."} {"geneset":"GO_CELLULAR_RESPONSE_TO_OXYGEN_RADICAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_OXYGEN_RADICAL","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion."} {"geneset":"GO_REGULATION_OF_CILIUM_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CILIUM_MOVEMENT","description":"Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium."} {"geneset":"GO_PURINE_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."} {"geneset":"GO_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION","description":"Any process that activates or increases the frequency, rate, or extent of peptide secretion."} {"geneset":"GO_RESPONSE_TO_DEXAMETHASONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_DEXAMETHASONE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus."} {"geneset":"GO_STEROL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROL_TRANSPORT","description":"The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."} {"geneset":"GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of organonitrogen compound."} {"geneset":"GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS_VIA_SOMATIC_MUTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS_VIA_SOMATIC_MUTATION","description":"The process in which immune receptor genes are diversified through somatic mutation."} {"geneset":"GO_REGULATION_OF_CHROMOSOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHROMOSOME_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome."} {"geneset":"GO_EMBRYONIC_EYE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_EYE_MORPHOGENESIS","description":"The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized."} {"geneset":"GO_BLASTOCYST_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLASTOCYST_GROWTH","description":"An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation."} {"geneset":"GO_ESTROGEN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTROGEN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."} {"geneset":"GO_REGULATION_OF_CELL_MATRIX_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_MATRIX_ADHESION","description":"Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix."} {"geneset":"GO_VISUAL_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VISUAL_BEHAVIOR","description":"The behavior of an organism in response to a visual stimulus."} {"geneset":"GO_LIPOSACCHARIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOSACCHARIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving liposaccharide."} {"geneset":"GO_REGULATION_OF_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_ADHESION","description":"Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix."} {"geneset":"GO_INTRACELLULAR_LIPID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_LIPID_TRANSPORT","description":"The directed movement of lipids within cells."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interferon-alpha production."} {"geneset":"GO_NEGATIVE_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter."} {"geneset":"GO_REGULATION_OF_ACTIN_FILAMENT_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIN_FILAMENT_DEPOLYMERIZATION","description":"Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament."} {"geneset":"GO_ENDOCRINE_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCRINE_SYSTEM_DEVELOPMENT","description":"Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes."} {"geneset":"GO_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation."} {"geneset":"GO_HYDROGEN_PEROXIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROGEN_PEROXIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."} {"geneset":"GO_RESPONSE_TO_DSRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_DSRNA","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus."} {"geneset":"GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR","description":"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator."} {"geneset":"GO_GLYCEROLIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCEROLIPID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone."} {"geneset":"GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION","description":"Any process that activates or increases the frequency, rate or extent of actin polymerization."} {"geneset":"GO_AMINE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."} {"geneset":"GO_REGULATION_OF_STEROID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STEROID_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids."} {"geneset":"GO_MATURE_B_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATURE_B_CELL_DIFFERENTIATION","description":"The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development."} {"geneset":"GO_C21_STEROID_HORMONE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_C21_STEROID_HORMONE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones."} {"geneset":"GO_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT","description":"The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state."} {"geneset":"GO_STEROL_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROL_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."} {"geneset":"GO__DE_NOVO_PROTEIN_FOLDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO__DE_NOVO_PROTEIN_FOLDING","description":"The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure."} {"geneset":"GO_REGULATION_OF_PHAGOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHAGOCYTOSIS","description":"Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material."} {"geneset":"GO_DNA_INTEGRITY_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_INTEGRITY_CHECKPOINT","description":"A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes."} {"geneset":"GO_MEMBRANE_PROTEIN_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_PROTEIN_PROTEOLYSIS","description":"The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains."} {"geneset":"GO_POSITIVE_REGULATION_OF_OSTEOBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_OSTEOBLAST_PROLIFERATION","description":"Any process that activates or increases the rate or extent of osteoblast proliferation."} {"geneset":"GO_TRNA_THREONYLCARBAMOYLADENOSINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_THREONYLCARBAMOYLADENOSINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules."} {"geneset":"GO_TUBE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TUBE_MORPHOGENESIS","description":"The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system."} {"geneset":"GO_ARP2_3_COMPLEX_MEDIATED_ACTIN_NUCLEATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARP2_3_COMPLEX_MEDIATED_ACTIN_NUCLEATION","description":"The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins."} {"geneset":"GO_REGULATION_OF_HYDROGEN_PEROXIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HYDROGEN_PEROXIDE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide."} {"geneset":"GO_REGULATION_OF_EMBRYONIC_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EMBRYONIC_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of embryonic development."} {"geneset":"GO_SENSORY_ORGAN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_ORGAN_DEVELOPMENT","description":"The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure."} {"geneset":"GO_RETINA_VASCULATURE_DEVELOPMENT_IN_CAMERA_TYPE_EYE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINA_VASCULATURE_DEVELOPMENT_IN_CAMERA_TYPE_EYE","description":"The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of MAP kinase activity."} {"geneset":"GO_BONE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_MORPHOGENESIS","description":"The process in which bones are generated and organized."} {"geneset":"GO_CELL_PROJECTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PROJECTION_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon."} {"geneset":"GO_REGULATION_OF_MEMBRANE_INVAGINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEMBRANE_INVAGINATION","description":"Any process that modulates the frequency, rate or extent of membrane invagination."} {"geneset":"GO_ISOPRENOID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ISOPRENOID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."} {"geneset":"GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_GOLGI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_GOLGI","description":"The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport."} {"geneset":"GO_MITOCHONDRIAL_GENOME_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_GENOME_MAINTENANCE","description":"The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome."} {"geneset":"GO_COENZYME_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COENZYME_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed."} {"geneset":"GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE","description":"Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation."} {"geneset":"GO_GLUCAN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCAN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues."} {"geneset":"GO_LINOLEIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LINOLEIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2."} {"geneset":"GO_NEGATIVE_REGULATION_OF_COFACTOR_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_COFACTOR_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor."} {"geneset":"GO_MRNA_CIS_SPLICING_VIA_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_CIS_SPLICING_VIA_SPLICEOSOME","description":"The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript."} {"geneset":"GO_VIRAL_LATENCY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VIRAL_LATENCY","description":"The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate."} {"geneset":"GO_CYTOPLASMIC_SEQUESTERING_OF_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_SEQUESTERING_OF_PROTEIN","description":"The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell."} {"geneset":"GO_REGULATION_OF_SPINDLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SPINDLE_ASSEMBLY","description":"Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STEROL_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STEROL_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INFLAMMATORY_RESPONSE","description":"Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents."} {"geneset":"GO_OLIGODENDROCYTE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLIGODENDROCYTE_DEVELOPMENT","description":"The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system."} {"geneset":"GO_RESPONSE_TO_INTERFERON_GAMMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_INTERFERON_GAMMA","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon."} {"geneset":"GO_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","description":"A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_MITOCHONDRION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_MITOCHONDRION","description":"A process in which a protein is transported to, or maintained in, a location within the mitochondrion."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS","description":"Any process that stops, prevents or reduces frequency, rate or extent of chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION","description":"Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation."} {"geneset":"GO_POSITIVE_REGULATION_OF_BLOOD_CIRCULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BLOOD_CIRCULATION","description":"Any process that activates or increases the frequency, rate or extent of blood circulation."} {"geneset":"GO_MICROTUBULE_BASED_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_BASED_MOVEMENT","description":"A microtubule-based process that is mediated by motor proteins and results in the movement of organelles, other microtubules, or other particles along microtubules."} {"geneset":"GO_SENSORY_ORGAN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SENSORY_ORGAN_MORPHOGENESIS","description":"Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."} {"geneset":"GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION","description":"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex."} {"geneset":"GO_RESPONSE_TO_HYDROPEROXIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_HYDROPEROXIDE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH."} {"geneset":"GO_PROTEIN_COMPLEX_SUBUNIT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_COMPLEX_SUBUNIT_ORGANIZATION","description":"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex."} {"geneset":"GO_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT","description":"Any process that modulates the frequency, rate or extent of actin filament-based movement."} {"geneset":"GO_CHROMATIN_SILENCING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_SILENCING","description":"Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin."} {"geneset":"GO_MAINTENANCE_OF_PROTEIN_LOCATION_IN_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAINTENANCE_OF_PROTEIN_LOCATION_IN_NUCLEUS","description":"Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ESTRADIOL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ESTRADIOL_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen."} {"geneset":"GO_LOCOMOTORY_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOCOMOTORY_BEHAVIOR","description":"The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions."} {"geneset":"GO_RESPONSE_TO_EPINEPHRINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_EPINEPHRINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system."} {"geneset":"GO_REGULATION_OF_MACROPHAGE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MACROPHAGE_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of macrophage differentiation."} {"geneset":"GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS","description":"Any process that modulates the frequency, rate or extent of protein localization to nucleus."} {"geneset":"GO_NUCLEUS_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEUS_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus."} {"geneset":"GO_TRABECULA_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRABECULA_FORMATION","description":"The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."} {"geneset":"GO_SUBSTRATE_DEPENDENT_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUBSTRATE_DEPENDENT_CELL_MIGRATION","description":"The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate."} {"geneset":"GO_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC","description":"The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."} {"geneset":"GO_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription."} {"geneset":"GO_RETINA_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINA_HOMEOSTASIS","description":"A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function."} {"geneset":"GO_POSITIVE_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate, or extent of a humoral immune response."} {"geneset":"GO_MITOCHONDRION_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRION_MORPHOGENESIS","description":"The process in which the anatomical structures of a mitochondrion are generated and organized."} {"geneset":"GO_COPPER_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COPPER_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell."} {"geneset":"GO_STEM_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEM_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."} {"geneset":"GO_DOPAMINERGIC_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOPAMINERGIC_NEURON_DIFFERENTIATION","description":"The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine."} {"geneset":"GO_MAGNESIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAGNESIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of magnesium ion across a membrane."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum."} {"geneset":"GO_REGULATION_OF_CHOLESTEROL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CHOLESTEROL_METABOLIC_PROCESS","description":"Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."} {"geneset":"GO_SCHWANN_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SCHWANN_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function."} {"geneset":"GO_DIVALENT_INORGANIC_ANION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIVALENT_INORGANIC_ANION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell."} {"geneset":"GO_PROTEIN_COMPLEX_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_COMPLEX_LOCALIZATION","description":"A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GTPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GTPASE_ACTIVITY","description":"Any process that stops or reduces the rate of GTP hydrolysis by a GTPase."} {"geneset":"GO_PROTEIN_HOMOTRIMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HOMOTRIMERIZATION","description":"The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits."} {"geneset":"GO_RESPONSE_TO_MINERALOCORTICOID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MINERALOCORTICOID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway."} {"geneset":"GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT5_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT5_PROTEIN","description":"Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat5 protein."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species."} {"geneset":"GO_COENZYME_A_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COENZYME_A_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DIGESTIVE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DIGESTIVE_SYSTEM_PROCESS","description":"Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."} {"geneset":"GO_NUCLEOSIDE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_TRANSPORT","description":"The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a neuron."} {"geneset":"GO_FLAVONOID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FLAVONOID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins."} {"geneset":"GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome."} {"geneset":"GO_UDP_N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UDP_N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."} {"geneset":"GO_FERTILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FERTILIZATION","description":"The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-2 production."} {"geneset":"GO_GOLGI_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_LOCALIZATION","description":"Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell."} {"geneset":"GO_G2_DNA_DAMAGE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G2_DNA_DAMAGE_CHECKPOINT","description":"A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage."} {"geneset":"GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE","description":"Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species."} {"geneset":"GO_REGULATION_OF_CELL_PROJECTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_PROJECTION_ASSEMBLY","description":"Any process that modulates the rate, frequency, or extent of cell projection assembly."} {"geneset":"GO_REGULATION_OF_HEART_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HEART_GROWTH","description":"Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."} {"geneset":"GO_IONOTROPIC_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IONOTROPIC_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_NEURON_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_FATE_COMMITMENT","description":"The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron."} {"geneset":"GO_REGULATION_OF_CELLULAR_RESPIRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_RESPIRATION","description":"Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds."} {"geneset":"GO_REGULATION_OF_TELOMERE_CAPPING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TELOMERE_CAPPING","description":"Any process that modulates the frequency, rate or extent of telomere capping."} {"geneset":"GO_TROPHECTODERMAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TROPHECTODERMAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell."} {"geneset":"GO_SPERMATID_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERMATID_DIFFERENTIATION","description":"The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."} {"geneset":"GO_GOLGI_VESICLE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_VESICLE_TRANSPORT","description":"The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles."} {"geneset":"GO_RESPONSE_TO_X_RAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_X_RAY","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)."} {"geneset":"GO_NUCLEOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOPHAGY","description":"A selective form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded."} {"geneset":"GO_APOPTOTIC_PROCESS_INVOLVED_IN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APOPTOTIC_PROCESS_INVOLVED_IN_MORPHOGENESIS","description":"Any apoptotic process that contributes to the shaping of an anatomical structure."} {"geneset":"GO_GLIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLIAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of a glial cell."} {"geneset":"GO_PHOSPHATIDYLSERINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLSERINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes."} {"geneset":"GO_NEURAL_TUBE_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURAL_TUBE_FORMATION","description":"The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system."} {"geneset":"GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION","description":"Any process that modulates the frequency, rate or extent of cell cycle phase transition."} {"geneset":"GO_PROTEIN_K63_LINKED_DEUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_K63_LINKED_DEUBIQUITINATION","description":"A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein."} {"geneset":"GO_ATP_HYDROLYSIS_COUPLED_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATP_HYDROLYSIS_COUPLED_TRANSMEMBRANE_TRANSPORT","description":"The transport of molecules across a membrane and against an electrochemical gradient, using energy from ATP hydrolysis."} {"geneset":"GO_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY","description":"A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand."} {"geneset":"GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process."} {"geneset":"GO_REGULATION_OF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors."} {"geneset":"GO_POSITIVE_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."} {"geneset":"GO_CEREBELLAR_CORTEX_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBELLAR_CORTEX_FORMATION","description":"The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."} {"geneset":"GO_REGULATION_OF_PEPTIDE_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PEPTIDE_SECRETION","description":"Any process that modulates the frequency, rate, or extent of peptide secretion."} {"geneset":"GO_PYRIMIDINE_NUCLEOSIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOSIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_KETONE_BODY_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KETONE_BODY_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving ketone body."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_13_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_13_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-13 production."} {"geneset":"GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN","description":"Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat3 protein."} {"geneset":"GO_HEART_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEART_GROWTH","description":"The increase in size or mass of the heart."} {"geneset":"GO_LYMPHOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_MIGRATION","description":"The movement of a lymphocyte within or between different tissues and organs of the body."} {"geneset":"GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING","description":"The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_SUMOYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_SUMOYLATION","description":"Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein."} {"geneset":"GO_ADULT_HEART_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADULT_HEART_DEVELOPMENT","description":"The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_ACETYLATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation."} {"geneset":"GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS","description":"Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."} {"geneset":"GO_RESPONSE_TO_BIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_BIOTIC_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism."} {"geneset":"GO_OUTFLOW_TRACT_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OUTFLOW_TRACT_MORPHOGENESIS","description":"The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries."} {"geneset":"GO_NUCLEAR_EXPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_EXPORT","description":"The directed movement of substances out of the nucleus."} {"geneset":"GO_MEMBRANE_INVAGINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_INVAGINATION","description":"The infolding of a membrane, resulting in formation of a vesicle."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ERAD_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ERAD_PATHWAY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway."} {"geneset":"GO_AROMATIC_AMINO_ACID_FAMILY_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AROMATIC_AMINO_ACID_FAMILY_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."} {"geneset":"GO_RESPONSE_TO_TRANSITION_METAL_NANOPARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_TRANSITION_METAL_NANOPARTICLE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle."} {"geneset":"GO_REGULATION_OF_ACTIN_CYTOSKELETON_REORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIN_CYTOSKELETON_REORGANIZATION","description":"Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization."} {"geneset":"GO_HYDROGEN_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROGEN_TRANSPORT","description":"The directed movement of hydrogen (H2 or H+), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_NEURON_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_NEURON_DEATH","description":"Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron death."} {"geneset":"GO_ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT","description":"The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi."} {"geneset":"GO_RESPONSE_TO_TOXIC_SUBSTANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_TOXIC_SUBSTANCE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus."} {"geneset":"GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS","description":"Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."} {"geneset":"GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_6","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_6","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER","description":"Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter."} {"geneset":"GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION","description":"The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron."} {"geneset":"GO_STRIATUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRIATUM_DEVELOPMENT","description":"The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati."} {"geneset":"GO_NEUTROPHIL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUTROPHIL_MEDIATED_IMMUNITY","description":"Any process involved in the carrying out of an immune response by a neutrophil."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CHROMATIN_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CHROMATIN_MODIFICATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of chromatin modification."} {"geneset":"GO_CELLULAR_CHEMICAL_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_CHEMICAL_HOMEOSTASIS","description":"Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell."} {"geneset":"GO_CELLULAR_RESPONSE_TO_LEPTIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_LEPTIN_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism."} {"geneset":"GO_EPITHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_PROLIFERATION","description":"The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine."} {"geneset":"GO_REGULATION_OF_LIPOPROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPOPROTEIN_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."} {"geneset":"GO_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION","description":"Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."} {"geneset":"GO_REGULATION_OF_COFACTOR_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_COFACTOR_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor."} {"geneset":"GO_MYOTUBE_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOTUBE_CELL_DEVELOPMENT","description":"The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."} {"geneset":"GO_PHOSPHATIDYLGLYCEROL_ACYL_CHAIN_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLGLYCEROL_ACYL_CHAIN_REMODELING","description":"Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains."} {"geneset":"GO_FIBRINOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FIBRINOLYSIS","description":"A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin."} {"geneset":"GO_MONOCARBOXYLIC_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOCARBOXYLIC_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group."} {"geneset":"GO_THIOESTER_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THIOESTER_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol."} {"geneset":"GO_KERATINIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KERATINIZATION","description":"The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT","description":"Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."} {"geneset":"GO_MONOSACCHARIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOSACCHARIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."} {"geneset":"GO_REGULATION_OF_CELL_FATE_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_FATE_SPECIFICATION","description":"Any process that mediates the adoption of a specific fate by a cell."} {"geneset":"GO_CELLULAR_CARBOHYDRATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_CARBOHYDRATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells."} {"geneset":"GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_6_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_6_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MUSCLE_HYPERTROPHY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MUSCLE_HYPERTROPHY","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy."} {"geneset":"GO_POSITIVE_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS","description":"Any process that increases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus."} {"geneset":"GO_RECOMBINATIONAL_REPAIR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECOMBINATIONAL_REPAIR","description":"A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA."} {"geneset":"GO_RECIPROCAL_DNA_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECIPROCAL_DNA_RECOMBINATION","description":"A DNA recombination process that results in the equal exchange of genetic material between the recombining DNA molecules."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_KILLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_KILLING","description":"Any process that activates or increases the frequency, rate or extent of cell killing."} {"geneset":"GO_POSITIVE_REGULATION_OF_NUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NUCLEASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids."} {"geneset":"GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION","description":"Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule."} {"geneset":"GO_NEGATIVE_REGULATION_OF_OSSIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_OSSIFICATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of bone formation."} {"geneset":"GO_REGULATION_OF_SKELETAL_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SKELETAL_MUSCLE_CONTRACTION","description":"Any process that modulates the frequency, rate or extent of skeletal muscle contraction."} {"geneset":"GO_CELLULAR_RESPONSE_TO_PEPTIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_PEPTIDE","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus."} {"geneset":"GO_REGULATION_OF_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_REPLICATION","description":"Any process that modulates the frequency, rate or extent of DNA replication."} {"geneset":"GO_C_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_C_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION","description":"The alteration of the C-terminal amino acid residue in a protein."} {"geneset":"GO_REGULATION_OF_ORGANELLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ORGANELLE_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of organelle assembly."} {"geneset":"GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY","description":"The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_ADHESION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation."} {"geneset":"GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of transition metal ions at the level of a cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver."} {"geneset":"GO_CELL_CELL_RECOGNITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_RECOGNITION","description":"Cell recognition between cells. May involve the formation of specialized cell junctions."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA."} {"geneset":"GO_SKELETAL_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKELETAL_MUSCLE_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle."} {"geneset":"GO_RNA_3_END_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_3_END_PROCESSING","description":"Any process involved in forming the mature 3' end of an RNA molecule."} {"geneset":"GO_RESPONSE_TO_ANTIBIOTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ANTIBIOTIC","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms."} {"geneset":"GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_RENIN_ANGIOTENSIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_RENIN_ANGIOTENSIN","description":"The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system."} {"geneset":"GO_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."} {"geneset":"GO_CELL_ADHESION_MEDIATED_BY_INTEGRIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_ADHESION_MEDIATED_BY_INTEGRIN","description":"The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits."} {"geneset":"GO_CELL_FATE_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_FATE_SPECIFICATION","description":"The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."} {"geneset":"GO_CELLULAR_RESPONSE_TO_GLUCOSE_STARVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_GLUCOSE_STARVATION","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose."} {"geneset":"GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE","description":"Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response."} {"geneset":"GO_WOUND_HEALING_SPREADING_OF_EPIDERMAL_CELLS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WOUND_HEALING_SPREADING_OF_EPIDERMAL_CELLS","description":"The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_MONOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOCYTE_CHEMOTAXIS","description":"The movement of a monocyte in response to an external stimulus."} {"geneset":"GO_CEREBRAL_CORTEX_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBRAL_CORTEX_CELL_MIGRATION","description":"The orderly movement of cells from one site to another in the cerebral cortex."} {"geneset":"GO_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of Wnt signal transduction."} {"geneset":"GO_FOLIC_ACID_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOLIC_ACID_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units."} {"geneset":"GO_MYELOID_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages."} {"geneset":"GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT","description":"Any process that modulates the frequency, rate or extent of the movement of a cellular component."} {"geneset":"GO_TELENCEPHALON_REGIONALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELENCEPHALON_REGIONALIZATION","description":"The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops."} {"geneset":"GO_CELLULAR_RESPONSE_TO_OSMOTIC_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_OSMOTIC_STRESS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."} {"geneset":"GO_REGULATION_OF_INTERFERON_GAMMA_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERFERON_GAMMA_SECRETION","description":"Any process that modulates the frequency, rate or extent of interferon-gamma secretion."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_INTERFERON_GAMMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_INTERFERON_GAMMA","description":"Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."} {"geneset":"GO_REGULATION_OF_DENDRITIC_SPINE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DENDRITIC_SPINE_MORPHOGENESIS","description":"Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."} {"geneset":"GO_CELLULAR_COPPER_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_COPPER_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell."} {"geneset":"GO_RESPONSE_TO_ACIDIC_PH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ACIDIC_PH","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution."} {"geneset":"GO_REGULATION_OF_RENAL_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RENAL_SYSTEM_PROCESS","description":"Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system."} {"geneset":"GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process."} {"geneset":"GO_PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands."} {"geneset":"GO_CARDIAC_CHAMBER_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CHAMBER_FORMATION","description":"The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart."} {"geneset":"GO_PLACENTA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLACENTA_DEVELOPMENT","description":"The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."} {"geneset":"GO_POSITIVE_REGULATION_OF_JUN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_JUN_KINASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of JUN kinase activity."} {"geneset":"GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation."} {"geneset":"GO_LENS_MORPHOGENESIS_IN_CAMERA_TYPE_EYE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LENS_MORPHOGENESIS_IN_CAMERA_TYPE_EYE","description":"The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus."} {"geneset":"GO_ERAD_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERAD_PATHWAY","description":"The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome."} {"geneset":"GO_MYELIN_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELIN_MAINTENANCE","description":"The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath."} {"geneset":"GO_CELL_CELL_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_JUNCTION_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a junction between cells."} {"geneset":"GO_LIPID_STORAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_STORAGE","description":"The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."} {"geneset":"GO_MEMBRANE_LIPID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_LIPID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane."} {"geneset":"GO_REGULATION_OF_EXTENT_OF_CELL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXTENT_OF_CELL_GROWTH","description":"Any process that modulates the extent of cell growth."} {"geneset":"GO_ACTIN_FILAMENT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_8_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_8_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8."} {"geneset":"GO_CELL_VOLUME_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_VOLUME_HOMEOSTASIS","description":"Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell."} {"geneset":"GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL","description":"Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria."} {"geneset":"GO_GMP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GMP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving GMP, guanosine monophosphate."} {"geneset":"GO_RENAL_ABSORPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_ABSORPTION","description":"A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)."} {"geneset":"GO_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS","description":"Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis."} {"geneset":"GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway."} {"geneset":"GO_EPITHELIAL_STRUCTURE_MAINTENANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_STRUCTURE_MAINTENANCE","description":"A tissue homeostatic process required for the maintenance of epithelial structure."} {"geneset":"GO_PEPTIDYL_LYSINE_TRIMETHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_LYSINE_TRIMETHYLATION","description":"The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine."} {"geneset":"GO_PROTEIN_REFOLDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_REFOLDING","description":"The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones."} {"geneset":"GO_RRNA_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION","description":"Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."} {"geneset":"GO_REGULATION_OF_LEUKOCYTE_DEGRANULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LEUKOCYTE_DEGRANULATION","description":"Any process that modulates the frequency, rate, or extent of leukocyte degranulation."} {"geneset":"GO_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms."} {"geneset":"GO_RESPONSE_TO_SALT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_SALT","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus."} {"geneset":"GO_REGULATION_OF_CYTOPLASMIC_TRANSLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CYTOPLASMIC_TRANSLATION","description":"Any process that modulates the frequency, rate or extent of cytoplasmic translation."} {"geneset":"GO_RESPONSE_TO_FUNGUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_FUNGUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus."} {"geneset":"GO_ENDOCHONDRAL_BONE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCHONDRAL_BONE_MORPHOGENESIS","description":"The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone."} {"geneset":"GO_DETECTION_OF_TEMPERATURE_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_TEMPERATURE_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION","description":"The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception."} {"geneset":"GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY","description":"The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances."} {"geneset":"GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process."} {"geneset":"GO_SULFUR_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFUR_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine."} {"geneset":"GO_RESPONSE_TO_OXYGEN_RADICAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_OXYGEN_RADICAL","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion."} {"geneset":"GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process."} {"geneset":"GO_REGULATION_OF_HORMONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HORMONE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone."} {"geneset":"GO_PROTEIN_ACYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_ACYLATION","description":"The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid."} {"geneset":"GO_CRANIOFACIAL_SUTURE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CRANIOFACIAL_SUTURE_MORPHOGENESIS","description":"The process in which any suture between cranial and/or facial bones is generated and organized."} {"geneset":"GO_REGULATION_OF_LIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPID_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids."} {"geneset":"GO_KIDNEY_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KIDNEY_MORPHOGENESIS","description":"Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_LOCALIZATION_WITHIN_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOCALIZATION_WITHIN_MEMBRANE","description":"Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane."} {"geneset":"GO_CYTOKINESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINESIS","description":"The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells."} {"geneset":"GO_REGULATION_OF_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM","description":"Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum."} {"geneset":"GO_HEME_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEME_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors."} {"geneset":"GO_NEURON_PROJECTION_GUIDANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_GUIDANCE","description":"The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues."} {"geneset":"GO_POSITIVE_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS","description":"Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis."} {"geneset":"GO_CHONDROITIN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHONDROITIN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."} {"geneset":"GO_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_PROSTATE_GLAND_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_PROSTATE_GLAND_DEVELOPMENT","description":"The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland."} {"geneset":"GO_PROTEIN_PALMITOYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_PALMITOYLATION","description":"The covalent attachment of a palmitoyl group to a protein."} {"geneset":"GO_DORSAL_VENTRAL_AXIS_SPECIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DORSAL_VENTRAL_AXIS_SPECIFICATION","description":"The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."} {"geneset":"GO_PROTEIN_CHROMOPHORE_LINKAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_CHROMOPHORE_LINKAGE","description":"The covalent or noncovalent attachment of a chromophore to a protein."} {"geneset":"GO_REGULATION_OF_P38MAPK_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_P38MAPK_CASCADE","description":"Any process that modulates the frequency, rate or extent of p38MAPK cascade."} {"geneset":"GO_FEEDING_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FEEDING_BEHAVIOR","description":"Behavior associated with the intake of food."} {"geneset":"GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","description":"Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_1_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_1_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell."} {"geneset":"GO_REGULATION_OF_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ESTABLISHMENT_OR_MAINTENANCE_OF_BIPOLAR_CELL_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OR_MAINTENANCE_OF_BIPOLAR_CELL_POLARITY","description":"Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns."} {"geneset":"GO_FOREBRAIN_NEURON_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOREBRAIN_NEURON_FATE_COMMITMENT","description":"The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain."} {"geneset":"GO_SULFUR_AMINO_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFUR_AMINO_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine."} {"geneset":"GO_CELLULAR_RESPONSE_TO_VITAMIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_VITAMIN","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus."} {"geneset":"GO_PEPTIDE_HORMONE_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_HORMONE_PROCESSING","description":"The generation of a mature peptide hormone by posttranslational processing of a prohormone."} {"geneset":"GO_CELLULAR_RESPONSE_TO_VITAMIN_D","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_VITAMIN_D","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS","description":"Any process that modulates the frequency, rate or extent of response to oxidative stress."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS","description":"Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm."} {"geneset":"GO_GTP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GTP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving GTP, guanosine triphosphate."} {"geneset":"GO_PROTEIN_K48_LINKED_UBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_K48_LINKED_UBIQUITINATION","description":"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation."} {"geneset":"GO_MACROMITOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMITOPHAGY","description":"Degradation of a mitochondrion by macroautophagy."} {"geneset":"GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DUPLEX_UNWINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DUPLEX_UNWINDING","description":"The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage."} {"geneset":"GO_T_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_MEDIATED_IMMUNITY","description":"Any process involved in the carrying out of an immune response by a T cell."} {"geneset":"GO_DNA_DAMAGE_RESPONSE_DETECTION_OF_DNA_DAMAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DAMAGE_RESPONSE_DETECTION_OF_DNA_DAMAGE","description":"The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal."} {"geneset":"GO_MITOCHONDRION_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRION_LOCALIZATION","description":"Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell."} {"geneset":"GO_MATURATION_OF_5_8S_RRNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATURATION_OF_5_8S_RRNA","description":"Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule."} {"geneset":"GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport."} {"geneset":"GO_ASPARTATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASPARTATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid."} {"geneset":"GO_REGULATION_OF_DENDRITE_EXTENSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DENDRITE_EXTENSION","description":"Any process that modulates the frequency, rate or extent of dendrite extension."} {"geneset":"GO_MECHANOSENSORY_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MECHANOSENSORY_BEHAVIOR","description":"Behavior that is dependent upon the sensation of a mechanical stimulus."} {"geneset":"GO_BONE_RESORPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_RESORPTION","description":"The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products."} {"geneset":"GO_AXONEME_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXONEME_ASSEMBLY","description":"The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements."} {"geneset":"GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS","description":"Any process that modulates the frequency, rate, or extent of an immune effector process."} {"geneset":"GO_GANGLION_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GANGLION_DEVELOPMENT","description":"The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure."} {"geneset":"GO_REGULATION_OF_SECONDARY_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SECONDARY_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon."} {"geneset":"GO_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."} {"geneset":"GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."} {"geneset":"GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES","description":"The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell."} {"geneset":"GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS","description":"The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape."} {"geneset":"GO_CARDIAC_SEPTUM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_SEPTUM_MORPHOGENESIS","description":"The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_CELL_FATE_COMMITMENT","description":"Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate."} {"geneset":"GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT","description":"The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron."} {"geneset":"GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY","description":"Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity."} {"geneset":"GO_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXOCYTOSIS","description":"A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. Steps that prepare vesicles for fusion with the membrane (e.g. docking and priming) are included in this process. This is the process in which most molecules are secreted from eukaryotic cells."} {"geneset":"GO_REGULATION_OF_HISTONE_H4_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HISTONE_H4_ACETYLATION","description":"Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group."} {"geneset":"GO_POSITIVE_REGULATION_OF_LIPID_STORAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LIPID_STORAGE","description":"Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."} {"geneset":"GO_PYRIMIDINE_NUCLEOSIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_NUCLEOSIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."} {"geneset":"GO_REGULATION_OF_SISTER_CHROMATID_COHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SISTER_CHROMATID_COHESION","description":"Any process that modulates the frequency, rate or extent of sister chromatid cohesion."} {"geneset":"GO_HEPARAN_SULFATE_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEPARAN_SULFATE_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues."} {"geneset":"GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION","description":"Any process that modulates the frequency, rate or extent of cardiac muscle contraction."} {"geneset":"GO_ZINC_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ZINC_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING","description":"Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling."} {"geneset":"GO_EYE_PHOTORECEPTOR_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EYE_PHOTORECEPTOR_CELL_DEVELOPMENT","description":"Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve."} {"geneset":"GO_NEGATIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation."} {"geneset":"GO_REGULATION_OF_VIRAL_INDUCED_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VIRAL_INDUCED_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm."} {"geneset":"GO_GLYCOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSYLATION","description":"The covalent attachment and further modification of carbohydrate residues to a substrate molecule."} {"geneset":"GO_ANGIOGENESIS_INVOLVED_IN_WOUND_HEALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANGIOGENESIS_INVOLVED_IN_WOUND_HEALING","description":"Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury."} {"geneset":"GO_REGULATION_OF_RECEPTOR_RECYCLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RECEPTOR_RECYCLING","description":"Any process that modulates the frequency, rate, or extent of receptor recycling."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_2_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_2_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-2 production."} {"geneset":"GO_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY","description":"Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of smoothened signaling."} {"geneset":"GO_NEUTROPHIL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUTROPHIL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway."} {"geneset":"GO_REGULATION_OF_MUSCLE_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MUSCLE_SYSTEM_PROCESS","description":"Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system."} {"geneset":"GO_ARACHIDONATE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARACHIDONATE_TRANSPORT","description":"The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_LONG_CHAIN_FATTY_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LONG_CHAIN_FATTY_ACID_TRANSPORT","description":"The directed movement of long-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."} {"geneset":"GO_ACTIN_NUCLEATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_NUCLEATION","description":"The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament."} {"geneset":"GO_CHROMATIN_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_REMODELING","description":"Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation."} {"geneset":"GO_IMPORT_INTO_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMPORT_INTO_CELL","description":"The directed movement of some substance from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis."} {"geneset":"GO_CALCIUM_INDEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_INDEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES","description":"The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction."} {"geneset":"GO_PHOSPHOLIPID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."} {"geneset":"GO_REGULATION_OF_EXTRACELLULAR_MATRIX_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXTRACELLULAR_MATRIX_DISASSEMBLY","description":"Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix."} {"geneset":"GO_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that modulates the frequency, rate or extent of pri-miRNA transcription from RNA polymerase II promoter."} {"geneset":"GO_COLLECTING_DUCT_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COLLECTING_DUCT_DEVELOPMENT","description":"The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder."} {"geneset":"GO_HEXOSE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEXOSE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule."} {"geneset":"GO_REGULATION_OF_TRIGLYCERIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRIGLYCERIDE_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS","description":"Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus."} {"geneset":"GO_NEUROMUSCULAR_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROMUSCULAR_PROCESS","description":"Any process pertaining to the functions of the nervous and muscular systems of an organism."} {"geneset":"GO_ACTIN_CYTOSKELETON_REORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_CYTOSKELETON_REORGANIZATION","description":"A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins."} {"geneset":"GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."} {"geneset":"GO_LIPID_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_LOCALIZATION","description":"Any process in which a lipid is transported to, or maintained in, a specific location."} {"geneset":"GO_HETEROCHROMATIN_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HETEROCHROMATIN_ORGANIZATION","description":"Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin."} {"geneset":"GO_GLAND_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLAND_DEVELOPMENT","description":"The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion."} {"geneset":"GO_RESPONSE_TO_MERCURY_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MERCURY_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus."} {"geneset":"GO_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity."} {"geneset":"GO_BETA_CATENIN_TCF_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_CATENIN_TCF_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex."} {"geneset":"GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY","description":"Any process that initiates the activity of an inactive protein kinase."} {"geneset":"GO_REGULATION_OF_CELL_CYCLE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_CYCLE_PROCESS","description":"Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."} {"geneset":"GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY","description":"Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns."} {"geneset":"GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response."} {"geneset":"GO_VESICLE_DOCKING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_DOCKING","description":"The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere."} {"geneset":"GO_OLIGODENDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLIGODENDROCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system."} {"geneset":"GO_NEUROMUSCULAR_SYNAPTIC_TRANSMISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROMUSCULAR_SYNAPTIC_TRANSMISSION","description":"The process of communication from a neuron to a muscle, across a synapse."} {"geneset":"GO_CELL_KILLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_KILLING","description":"Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions."} {"geneset":"GO_CELL_CYCLE_CHECKPOINT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CYCLE_CHECKPOINT","description":"A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction."} {"geneset":"GO_NEPHRON_TUBULE_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEPHRON_TUBULE_FORMATION","description":"The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ION_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_CEREBRAL_CORTEX_RADIALLY_ORIENTED_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBRAL_CORTEX_RADIALLY_ORIENTED_CELL_MIGRATION","description":"The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain."} {"geneset":"GO_LYMPH_VESSEL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPH_VESSEL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure."} {"geneset":"GO_RESPONSE_TO_CADMIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_CADMIUM_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus."} {"geneset":"GO_RESPONSE_TO_CYTOKINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_CYTOKINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus."} {"geneset":"GO_REGULATION_OF_CARDIAC_CONDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARDIAC_CONDUCTION","description":"Any process that modulates the frequency, rate or extent of cardiac conduction."} {"geneset":"GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS","description":"Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."} {"geneset":"GO_SPLICEOSOMAL_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPLICEOSOMAL_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions."} {"geneset":"GO_SNRNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SNRNA_PROCESSING","description":"Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of cell differentiation."} {"geneset":"GO_ATRIOVENTRICULAR_VALVE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATRIOVENTRICULAR_VALVE_DEVELOPMENT","description":"The progression of the atrioventricular valve over time, from its formation to the mature structure."} {"geneset":"GO_RRNA_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_MODIFICATION","description":"The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically."} {"geneset":"GO_POSITIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY","description":"Any process that activates or increases the activity of a monooxygenase."} {"geneset":"GO_POSITIVE_REGULATION_OF_DENDRITIC_SPINE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DENDRITIC_SPINE_MORPHOGENESIS","description":"Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."} {"geneset":"GO_PROSTATE_GLAND_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROSTATE_GLAND_DEVELOPMENT","description":"The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid."} {"geneset":"GO_MICROVILLUS_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROVILLUS_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell."} {"geneset":"GO_ADENOHYPOPHYSIS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADENOHYPOPHYSIS_DEVELOPMENT","description":"The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus."} {"geneset":"GO_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_6_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_6_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-6 production."} {"geneset":"GO_SECONDARY_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECONDARY_METABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GLUCONEOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GLUCONEOGENESIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis."} {"geneset":"GO_REGULATION_OF_TRANSMISSION_OF_NERVE_IMPULSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSMISSION_OF_NERVE_IMPULSE","description":"Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation."} {"geneset":"GO_FATTY_ACID_DERIVATIVE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_DERIVATIVE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of fatty acid derivative."} {"geneset":"GO_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_PYRUVATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRUVATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving pyruvate, 2-oxopropanoate."} {"geneset":"GO_POSITIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway."} {"geneset":"GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity."} {"geneset":"GO_NITRIC_OXIDE_MEDIATED_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NITRIC_OXIDE_MEDIATED_SIGNAL_TRANSDUCTION","description":"Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms."} {"geneset":"GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT5_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT5_PROTEIN","description":"Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat5 protein."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process."} {"geneset":"GO_ESTABLISHMENT_OF_MITOTIC_SPINDLE_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_MITOTIC_SPINDLE_LOCALIZATION","description":"The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs."} {"geneset":"GO_STEROL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."} {"geneset":"GO_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE","description":"The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates."} {"geneset":"GO_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING","description":"Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism."} {"geneset":"GO_POST_ANAL_TAIL_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POST_ANAL_TAIL_MORPHOGENESIS","description":"The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance."} {"geneset":"GO_PEPTIDYL_ASPARAGINE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_ASPARAGINE_MODIFICATION","description":"The modification of peptidyl-asparagine."} {"geneset":"GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION","description":"Any process that activates or increases the rate or extent of endothelial cell proliferation."} {"geneset":"GO_CYTOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOLYSIS","description":"The rupture of cell membranes and the loss of cytoplasm."} {"geneset":"GO_REGULATION_OF_VIRAL_GENOME_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VIRAL_GENOME_REPLICATION","description":"Any process that modulates the frequency, rate or extent of viral genome replication."} {"geneset":"GO_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION","description":"The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."} {"geneset":"GO_REPRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REPRODUCTION","description":"The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms."} {"geneset":"GO_REGULATION_OF_STAT_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STAT_CASCADE","description":"Any process that modulates the frequency, rate or extent of STAT cascade."} {"geneset":"GO_REGULATION_OF_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ION_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_DORSAL_SPINAL_CORD_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DORSAL_SPINAL_CORD_DEVELOPMENT","description":"The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input."} {"geneset":"GO_NEURON_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_DEATH","description":"The process of cell death in a neuron."} {"geneset":"GO_POSITIVE_REGULATION_OF_AUTOPHAGY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_AUTOPHAGY","description":"Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."} {"geneset":"GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION","description":"A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate."} {"geneset":"GO_RECEPTOR_MEDIATED_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_MEDIATED_ENDOCYTOSIS","description":"An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles."} {"geneset":"GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY","description":"Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles."} {"geneset":"GO_2_OXOGLUTARATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_2_OXOGLUTARATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism."} {"geneset":"GO_TRYPTOPHAN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRYPTOPHAN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."} {"geneset":"GO_INOSITOL_PHOSPHATE_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_PHOSPHATE_MEDIATED_SIGNALING","description":"Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6)."} {"geneset":"GO_REGULATION_OF_MEMBRANE_PERMEABILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEMBRANE_PERMEABILITY","description":"Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane."} {"geneset":"GO_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of an androgen binding to its receptor."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."} {"geneset":"GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION","description":"Any process that activates or increases the frequency, rate or extent of stem cell proliferation."} {"geneset":"GO_GERM_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GERM_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."} {"geneset":"GO_DNA_LIGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_LIGATION","description":"The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."} {"geneset":"GO_REGULATION_OF_SPROUTING_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SPROUTING_ANGIOGENESIS","description":"Any process that modulates the frequency, rate or extent of sprouting angiogenesis."} {"geneset":"GO_CELLULAR_MACROMOLECULE_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_MACROMOLECULE_LOCALIZATION","description":"Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell."} {"geneset":"GO_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS","description":"Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus."} {"geneset":"GO_NEPHRON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEPHRON_DEVELOPMENT","description":"The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney."} {"geneset":"GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS","description":"Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus."} {"geneset":"GO_PURINE_CONTAINING_COMPOUND_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_CONTAINING_COMPOUND_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."} {"geneset":"GO_REGULATION_OF_LIPOPROTEIN_PARTICLE_CLEARANCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LIPOPROTEIN_PARTICLE_CLEARANCE","description":"Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."} {"geneset":"GO_PLATELET_DEGRANULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_DEGRANULATION","description":"The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet."} {"geneset":"GO_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE","description":"Any process that activates or increases the frequency, rate or extent of the inflammatory response."} {"geneset":"GO_LIPID_OXIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_OXIDATION","description":"The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen."} {"geneset":"GO_INTEGRIN_MEDIATED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTEGRIN_MEDIATED_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_NOTOCHORD_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NOTOCHORD_DEVELOPMENT","description":"The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column."} {"geneset":"GO_DICARBOXYLIC_ACID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DICARBOXYLIC_ACID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups."} {"geneset":"GO_NAD_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NAD_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."} {"geneset":"GO_REGULATION_OF_SULFUR_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SULFUR_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur."} {"geneset":"GO_SKIN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKIN_DEVELOPMENT","description":"The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue."} {"geneset":"GO_ADENYLATE_CYCLASE_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADENYLATE_CYCLASE_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP)."} {"geneset":"GO_MESODERM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESODERM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue."} {"geneset":"GO_GENITALIA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GENITALIA_DEVELOPMENT","description":"The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling."} {"geneset":"GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT1_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT1_PROTEIN","description":"Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat1 protein."} {"geneset":"GO_CELLULAR_RESPONSE_TO_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_STRESS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."} {"geneset":"GO_PATTERN_SPECIFICATION_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PATTERN_SPECIFICATION_PROCESS","description":"Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate."} {"geneset":"GO_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of alcohol biosynthetic process."} {"geneset":"GO_PHOSPHATIDIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids."} {"geneset":"GO_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication."} {"geneset":"GO_ANGIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANGIOGENESIS","description":"Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels."} {"geneset":"GO_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium."} {"geneset":"GO_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY","description":"Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity."} {"geneset":"GO_LYMPHOID_PROGENITOR_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOID_PROGENITOR_CELL_DIFFERENTIATION","description":"The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages."} {"geneset":"GO_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METHYLATION","description":"The process in which a methyl group is covalently attached to a molecule."} {"geneset":"GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT","description":"Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time."} {"geneset":"GO_PROTEIN_IMPORT_INTO_MITOCHONDRIAL_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_IMPORT_INTO_MITOCHONDRIAL_MATRIX","description":"The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together."} {"geneset":"GO_MODULATION_OF_SYNAPTIC_TRANSMISSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODULATION_OF_SYNAPTIC_TRANSMISSION","description":"Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse."} {"geneset":"GO_CELLULAR_RESPONSE_TO_REACTIVE_NITROGEN_SPECIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_REACTIVE_NITROGEN_SPECIES","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."} {"geneset":"GO_REGULATION_OF_CATECHOLAMINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CATECHOLAMINE_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines."} {"geneset":"GO_MELANOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MELANOCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a melanocyte."} {"geneset":"GO_RNA_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."} {"geneset":"GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING","description":"The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang."} {"geneset":"GO_ESTABLISHMENT_OF_MITOCHONDRION_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_MITOCHONDRION_LOCALIZATION","description":"The directed movement of the mitochondrion to a specific location."} {"geneset":"GO_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS_VIA_THE_MULTIVESICULAR_BODY_SORTING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS_VIA_THE_MULTIVESICULAR_BODY_SORTING_PATHWAY","description":"The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation."} {"geneset":"GO_FATTY_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_TRANSPORT","description":"The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."} {"geneset":"GO_VENTRICULAR_TRABECULA_MYOCARDIUM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRICULAR_TRABECULA_MYOCARDIUM_MORPHOGENESIS","description":"The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized."} {"geneset":"GO_REGULATION_OF_CELL_SHAPE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_SHAPE","description":"Any process that modulates the surface configuration of a cell."} {"geneset":"GO_ARACHIDONIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARACHIDONIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer."} {"geneset":"GO_RESPONSE_TO_ETHER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ETHER","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_INVOLVED_IN_CELLULAR_RESPONSE_TO_CHEMICAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_INVOLVED_IN_CELLULAR_RESPONSE_TO_CHEMICAL_STIMULUS","description":"Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_LAMELLIPODIUM_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LAMELLIPODIUM_ORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of lamellipodium organization."} {"geneset":"GO_REGULATION_OF_BLOOD_VOLUME_BY_RENIN_ANGIOTENSIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BLOOD_VOLUME_BY_RENIN_ANGIOTENSIN","description":"The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood."} {"geneset":"GO_RESPONSE_TO_NUTRIENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_NUTRIENT","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus."} {"geneset":"GO_ORGANELLE_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_LOCALIZATION","description":"Any process in which an organelle is transported to, and/or maintained in, a specific location."} {"geneset":"GO_VENOUS_BLOOD_VESSEL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENOUS_BLOOD_VESSEL_DEVELOPMENT","description":"The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed."} {"geneset":"GO_EXECUTION_PHASE_OF_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXECUTION_PHASE_OF_APOPTOSIS","description":"A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died."} {"geneset":"GO_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."} {"geneset":"GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE","description":"The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels."} {"geneset":"GO_TELENCEPHALON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELENCEPHALON_DEVELOPMENT","description":"The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived."} {"geneset":"GO_PROSTANOID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROSTANOID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure."} {"geneset":"GO_MEMBRANE_REPOLARIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_REPOLARIZATION","description":"The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."} {"geneset":"GO_CEREBELLAR_PURKINJE_CELL_LAYER_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBELLAR_PURKINJE_CELL_LAYER_MORPHOGENESIS","description":"The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."} {"geneset":"GO_CLATHRIN_MEDIATED_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_MEDIATED_ENDOCYTOSIS","description":"An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles."} {"geneset":"GO_PHOSPHATIDYLETHANOLAMINE_ACYL_CHAIN_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLETHANOLAMINE_ACYL_CHAIN_REMODELING","description":"Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains."} {"geneset":"GO_RESPONSE_TO_GONADOTROPIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_GONADOTROPIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus."} {"geneset":"GO_CAMERA_TYPE_EYE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CAMERA_TYPE_EYE_MORPHOGENESIS","description":"The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field."} {"geneset":"GO_RESPONSE_TO_COBALT_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_COBALT_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus."} {"geneset":"GO_NEUROTROPHIN_TRK_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTROPHIN_TRK_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_MATERNAL_PLACENTA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATERNAL_PLACENTA_DEVELOPMENT","description":"Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."} {"geneset":"GO_MACROMOLECULE_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMOLECULE_METHYLATION","description":"The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule."} {"geneset":"GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE","description":"A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals."} {"geneset":"GO_REGULATION_OF_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION","description":"Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction."} {"geneset":"GO_CHROMATIN_SILENCING_AT_RDNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_SILENCING_AT_RDNA","description":"Repression of transcription of ribosomal DNA by altering the structure of chromatin."} {"geneset":"GO_RESPONSE_TO_FOLIC_ACID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_FOLIC_ACID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus."} {"geneset":"GO_GROWTH_PLATE_CARTILAGE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GROWTH_PLATE_CARTILAGE_DEVELOPMENT","description":"The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow."} {"geneset":"GO_O_GLYCAN_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_O_GLYCAN_PROCESSING","description":"The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides."} {"geneset":"GO_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers."} {"geneset":"GO_REGULATION_OF_AUTOPHAGOSOME_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_AUTOPHAGOSOME_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of autophagosome assembly."} {"geneset":"GO_NEUTRAL_AMINO_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUTRAL_AMINO_ACID_TRANSPORT","description":"The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species."} {"geneset":"GO_MESENCHYME_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESENCHYME_MORPHOGENESIS","description":"The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells."} {"geneset":"GO_CENTROSOME_DUPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTROSOME_DUPLICATION","description":"The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."} {"geneset":"GO_REGULATION_OF_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BINDING","description":"Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."} {"geneset":"GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE","description":"Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CHEMOTAXIS","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient."} {"geneset":"GO_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION","description":"Any process that modulates the frequency, rate or extent of Rho protein signal transduction."} {"geneset":"GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS","description":"Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process."} {"geneset":"GO_REGULATION_OF_ARF_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ARF_PROTEIN_SIGNAL_TRANSDUCTION","description":"Any process that modulates the frequency, rate or extent of ARF protein signal transduction."} {"geneset":"GO_PROTEIN_AUTOPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_AUTOPHOSPHORYLATION","description":"The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation)."} {"geneset":"GO_CELLULAR_COMPONENT_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_COMPONENT_DISASSEMBLY","description":"A cellular process that results in the breakdown of a cellular component."} {"geneset":"GO_REGULATION_OF_GLIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLIOGENESIS","description":"Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia."} {"geneset":"GO_AMINOGLYCAN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINOGLYCAN_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."} {"geneset":"GO_POSITIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a muscle cell."} {"geneset":"GO_ACTIVATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY","description":"Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity."} {"geneset":"GO_PHOSPHATIDYLCHOLINE_ACYL_CHAIN_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLCHOLINE_ACYL_CHAIN_REMODELING","description":"Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains."} {"geneset":"GO_RNA_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_LOCALIZATION","description":"A process in which RNA is transported to, or maintained in, a specific location."} {"geneset":"GO_MULTI_ORGANISM_MEMBRANE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTI_ORGANISM_MEMBRANE_ORGANIZATION","description":"A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism."} {"geneset":"GO_POSITIVE_REGULATION_OF_EMBRYONIC_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EMBRYONIC_DEVELOPMENT","description":"Any process that activates or increases the frequency, rate or extent of embryonic development."} {"geneset":"GO_HISTONE_H4_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H4_ACETYLATION","description":"The modification of histone H4 by the addition of an acetyl group."} {"geneset":"GO_MATING_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MATING_BEHAVIOR","description":"The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes."} {"geneset":"GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS","description":"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis."} {"geneset":"GO_REGULATION_OF_PROTEIN_POLYUBIQUITINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_POLYUBIQUITINATION","description":"Any process that modulates the frequency, rate or extent of protein polyubiquitination."} {"geneset":"GO_INACTIVATION_OF_MAPK_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INACTIVATION_OF_MAPK_ACTIVITY","description":"Any process that terminates the activity of the active enzyme MAP kinase."} {"geneset":"GO_PEPTIDYL_ARGININE_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_ARGININE_METHYLATION","description":"The addition of a methyl group to an arginine residue in a protein."} {"geneset":"GO_NEGATIVE_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway."} {"geneset":"GO_HISTONE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_PHOSPHORYLATION","description":"The modification of histones by addition of phosphate groups."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY","description":"Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."} {"geneset":"GO_MULTICELLULAR_ORGANISM_REPRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTICELLULAR_ORGANISM_REPRODUCTION","description":"The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NECROTIC_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NECROTIC_CELL_DEATH","description":"Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents."} {"geneset":"GO_REGULATION_OF_ORGANELLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ORGANELLE_ORGANIZATION","description":"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."} {"geneset":"GO_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHORYLATION","description":"The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide."} {"geneset":"GO_REGULATION_OF_STRIATED_MUSCLE_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STRIATED_MUSCLE_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."} {"geneset":"GO_STRIATED_MUSCLE_ADAPTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRIATED_MUSCLE_ADAPTATION","description":"Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."} {"geneset":"GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE","description":"The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder."} {"geneset":"GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION","description":"Any process that modulates the frequency, rate or extent of Ras protein signal transduction."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION","description":"Any process that stops, prevents, or reduces the rate of production of a cytokine."} {"geneset":"GO_POSITIVE_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT","description":"Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant."} {"geneset":"GO_PROSTATE_GLANDULAR_ACINUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROSTATE_GLANDULAR_ACINUS_DEVELOPMENT","description":"The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland."} {"geneset":"GO_REGULATION_OF_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEOLYSIS","description":"Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."} {"geneset":"GO_ENDOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCYTOSIS","description":"A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle."} {"geneset":"GO_PROTEIN_LOCALIZATION_TO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LOCALIZATION_TO_NUCLEUS","description":"A process in which a protein is transported to, or maintained in, a location within the nucleus."} {"geneset":"GO_PEPTIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another."} {"geneset":"GO_REGULATION_OF_MHC_CLASS_II_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MHC_CLASS_II_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II."} {"geneset":"GO_RAC_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAC_PROTEIN_SIGNAL_TRANSDUCTION","description":"A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state."} {"geneset":"GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport."} {"geneset":"GO_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL","description":"Any process that modulates the frequency, rate or extent of the viral entry into the host cell."} {"geneset":"GO_CELLULAR_COMPONENT_DISASSEMBLY_INVOLVED_IN_EXECUTION_PHASE_OF_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_COMPONENT_DISASSEMBLY_INVOLVED_IN_EXECUTION_PHASE_OF_APOPTOSIS","description":"The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis."} {"geneset":"GO_POSITIVE_REGULATION_OF_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SECRETION","description":"Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."} {"geneset":"GO_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_CYCLE","description":"Any process that activates or increases the rate or extent of progression through the cell cycle."} {"geneset":"GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION","description":"Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION","description":"Any process that activates or increases the frequency, rate or extent of B cell activation."} {"geneset":"GO_NEURONAL_ACTION_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURONAL_ACTION_POTENTIAL","description":"An action potential that occurs in a neuron."} {"geneset":"GO_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING","description":"Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening."} {"geneset":"GO_RETROGRADE_TRANSPORT_VESICLE_RECYCLING_WITHIN_GOLGI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETROGRADE_TRANSPORT_VESICLE_RECYCLING_WITHIN_GOLGI","description":"The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_10_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_10_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-10 production."} {"geneset":"GO_PARASYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PARASYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia."} {"geneset":"GO_BASEMENT_MEMBRANE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASEMENT_MEMBRANE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane."} {"geneset":"GO_SOMITE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMITE_DEVELOPMENT","description":"The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo."} {"geneset":"GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process."} {"geneset":"GO_NEGATIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL","description":"Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host cell."} {"geneset":"GO_SERINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SERINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."} {"geneset":"GO_SERTOLI_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SERTOLI_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport."} {"geneset":"GO_RNA_SPLICING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_SPLICING","description":"The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA."} {"geneset":"GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_POLYMERIZATION","description":"Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers."} {"geneset":"GO_REGULATION_OF_MUSCLE_ADAPTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MUSCLE_ADAPTATION","description":"Any process that modulates the frequency, rate or extent of muscle adaptation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING","description":"Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding."} {"geneset":"GO_OLFACTORY_BULB_INTERNEURON_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLFACTORY_BULB_INTERNEURON_DEVELOPMENT","description":"The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs."} {"geneset":"GO_FEMALE_GENITALIA_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FEMALE_GENITALIA_DEVELOPMENT","description":"The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure."} {"geneset":"GO_NEUROBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROBLAST_PROLIFERATION","description":"The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron."} {"geneset":"GO_ERYTHROSE_4_PHOSPHATE_PHOSPHOENOLPYRUVATE_FAMILY_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERYTHROSE_4_PHOSPHATE_PHOSPHOENOLPYRUVATE_FAMILY_AMINO_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid."} {"geneset":"GO_MIDGUT_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MIDGUT_DEVELOPMENT","description":"The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine."} {"geneset":"GO_MITOCHONDRION_DISTRIBUTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRION_DISTRIBUTION","description":"Any process that establishes the spatial arrangement of mitochondria between and within cells."} {"geneset":"GO_PEPTIDYL_METHIONINE_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_METHIONINE_MODIFICATION","description":"The modification of peptidyl-methionine."} {"geneset":"GO_IMMUNOLOGICAL_SYNAPSE_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNOLOGICAL_SYNAPSE_FORMATION","description":"The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction."} {"geneset":"GO_VITAMIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VITAMIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems."} {"geneset":"GO_MUSCLE_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate."} {"geneset":"GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST","description":"Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism."} {"geneset":"GO_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of neural precursor cell proliferation."} {"geneset":"GO_NUCLEOTIDE_SUGAR_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_SUGAR_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."} {"geneset":"GO_NEGATIVE_REGULATION_OF_AXONOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_AXONOGENESIS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis."} {"geneset":"GO_LEUKOCYTE_MIGRATION_INVOLVED_IN_INFLAMMATORY_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_MIGRATION_INVOLVED_IN_INFLAMMATORY_RESPONSE","description":"The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response."} {"geneset":"GO_OSTEOCLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OSTEOCLAST_DIFFERENTIATION","description":"The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue."} {"geneset":"GO_CARBOHYDRATE_DERIVATIVE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_DERIVATIVE_TRANSPORT","description":"The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_DEFINITIVE_HEMOPOIESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEFINITIVE_HEMOPOIESIS","description":"A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood."} {"geneset":"GO_RENAL_FILTRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_FILTRATION","description":"A renal system process in which fluid circulating through the body is filtered through a barrier system."} {"geneset":"GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."} {"geneset":"GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS","description":"Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis."} {"geneset":"GO_RESPONSE_TO_TUMOR_NECROSIS_FACTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_TUMOR_NECROSIS_FACTOR","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION","description":"Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules."} {"geneset":"GO_PROTEIN_ALKYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_ALKYLATION","description":"The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom."} {"geneset":"GO_ATRIOVENTRICULAR_VALVE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATRIOVENTRICULAR_VALVE_MORPHOGENESIS","description":"The process in which the structure of the atrioventricular valve is generated and organized."} {"geneset":"GO_REGULATION_OF_INTRACELLULAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRACELLULAR_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of substances within cells."} {"geneset":"GO_CARDIAC_CONDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CONDUCTION","description":"Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles."} {"geneset":"GO_AORTA_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AORTA_MORPHOGENESIS","description":"The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body."} {"geneset":"GO_RESPONSE_TO_ALCOHOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ALCOHOL","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus."} {"geneset":"GO_CELLULAR_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state at the level of the cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISM_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISM_GROWTH","description":"Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size."} {"geneset":"GO_MEMBRANE_LIPID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_LIPID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_DEPHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DEPHOSPHORYLATION","description":"Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule."} {"geneset":"GO_PROTEIN_INSERTION_INTO_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_INSERTION_INTO_MEMBRANE","description":"The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers."} {"geneset":"GO_ACTIVATION_OF_MAPK_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_MAPK_ACTIVITY","description":"The initiation of the activity of the inactive enzyme MAP kinase (MAPK)."} {"geneset":"GO_EMBRYONIC_ORGAN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_ORGAN_DEVELOPMENT","description":"Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."} {"geneset":"GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY","description":"Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity."} {"geneset":"GO_POSITIVE_REGULATION_OF_ORGAN_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ORGAN_GROWTH","description":"Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism."} {"geneset":"GO_EPOXYGENASE_P450_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPOXYGENASE_P450_PATHWAY","description":"The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids."} {"geneset":"GO_MAMMARY_GLAND_DUCT_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAMMARY_GLAND_DUCT_MORPHOGENESIS","description":"The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE","description":"Any process that decreases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane."} {"geneset":"GO_AMINO_ACID_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_ACID_IMPORT","description":"The directed movement of amino acids into a cell or organelle."} {"geneset":"GO_IMP_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMP_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION","description":"Any process that activates or increases the frequency, rate or extent of cell cycle G1/S phase transition."} {"geneset":"GO_LYMPHOCYTE_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_APOPTOTIC_PROCESS","description":"Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY","description":"Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."} {"geneset":"GO_FATTY_ACID_DERIVATIVE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_DERIVATIVE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving fatty acid derivative."} {"geneset":"GO_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interferon-alpha production."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_17_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_17_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."} {"geneset":"GO_GLYCOSYL_COMPOUND_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSYL_COMPOUND_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of glycosyl compound."} {"geneset":"GO_PROTEIN_HYDROXYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HYDROXYLATION","description":"The addition of a hydroxy group to a protein amino acid."} {"geneset":"GO_PEPTIDYL_LYSINE_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_LYSINE_METHYLATION","description":"The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_TUMOR_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_TUMOR_CELL","description":"Any process that modulates the frequency, rate, or extent of a response to tumor cell."} {"geneset":"GO_PROTEIN_TETRAMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TETRAMERIZATION","description":"The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits."} {"geneset":"GO_REGULATION_OF_TISSUE_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TISSUE_REMODELING","description":"Any process that modulates the frequency, rate, or extent of tissue remodeling."} {"geneset":"GO_RESPONSE_TO_ISOQUINOLINE_ALKALOID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ISOQUINOLINE_ALKALOID","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids."} {"geneset":"GO_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION","description":"Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine."} {"geneset":"GO_HISTONE_H3_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H3_ACETYLATION","description":"The modification of histone H3 by the addition of an acetyl group."} {"geneset":"GO_ENDOTHELIAL_TUBE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOTHELIAL_TUBE_MORPHOGENESIS","description":"The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."} {"geneset":"GO_REGULATION_OF_ANION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ANION_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_CELLULAR_RESPONSE_TO_DEXAMETHASONE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_DEXAMETHASONE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_REPLICATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication."} {"geneset":"GO_RESPONSE_TO_OSMOTIC_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_OSMOTIC_STRESS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING","description":"Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION","description":"Any process that activates or increases the frequency, rate, or extent of interleukin-6 production."} {"geneset":"GO_RUFFLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RUFFLE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell."} {"geneset":"GO_DNA_PACKAGING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_PACKAGING","description":"Any process in which DNA and associated proteins are formed into a compact, orderly structure."} {"geneset":"GO_MUSCLE_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_CELL_MIGRATION","description":"The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism."} {"geneset":"GO_BRANCHING_INVOLVED_IN_SALIVARY_GLAND_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRANCHING_INVOLVED_IN_SALIVARY_GLAND_MORPHOGENESIS","description":"The process in which the branching structure of the salivary gland is generated and organized."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter."} {"geneset":"GO_SINGLE_ORGANISM_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_ORGANISM_CATABOLIC_PROCESS","description":"A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves a single organism."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_MATURATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation."} {"geneset":"GO_BINDING_OF_SPERM_TO_ZONA_PELLUCIDA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BINDING_OF_SPERM_TO_ZONA_PELLUCIDA","description":"The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place."} {"geneset":"GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_EXONUCLEOLYTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_EXONUCLEOLYTIC","description":"The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides."} {"geneset":"GO_ADAPTATION_OF_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADAPTATION_OF_SIGNALING_PATHWAY","description":"The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus."} {"geneset":"GO_TRANSCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCYTOSIS","description":"The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side."} {"geneset":"GO_EPITHELIAL_CELL_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_MATURATION","description":"The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GENE_SILENCING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GENE_SILENCING","description":"Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation."} {"geneset":"GO_REGULATION_OF_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_DEVELOPMENT","description":"Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."} {"geneset":"GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway."} {"geneset":"GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE","description":"The directed movement of a protein to a specific location in the plasma membrane."} {"geneset":"GO_REGULATION_OF_MEMBRANE_REPOLARIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MEMBRANE_REPOLARIZATION","description":"Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative."} {"geneset":"GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION","description":"Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."} {"geneset":"GO_SNRNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SNRNA_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation."} {"geneset":"GO_PEPTIDYL_LYSINE_DIMETHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDYL_LYSINE_DIMETHYLATION","description":"The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine."} {"geneset":"GO_PROTEIN_IMPORT_INTO_PEROXISOME_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_IMPORT_INTO_PEROXISOME_MATRIX","description":"The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix."} {"geneset":"GO_POSITIVE_REGULATION_OF_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ATPASE_ACTIVITY","description":"Any process that activates or increases the rate of ATP hydrolysis by an ATPase."} {"geneset":"GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_GOLGI","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_GOLGI","description":"The directed movement of a protein to a specific location in the Golgi apparatus."} {"geneset":"GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport."} {"geneset":"GO_LIMBIC_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIMBIC_SYSTEM_DEVELOPMENT","description":"The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_KILLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_KILLING","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing."} {"geneset":"GO_POSITIVE_REGULATION_OF_MONOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MONOCYTE_CHEMOTAXIS","description":"Any process that increases the frequency, rate, or extent of monocyte chemotaxis."} {"geneset":"GO_REGULATION_OF_CELLULAR_PH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_PH","description":"Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation."} {"geneset":"GO_AXIS_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXIS_ELONGATION","description":"The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure."} {"geneset":"GO_REGULATION_OF_MITOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MITOTIC_CELL_CYCLE","description":"Any process that modulates the rate or extent of progress through the mitotic cell cycle."} {"geneset":"GO_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism."} {"geneset":"GO_T_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_DIFFERENTIATION","description":"The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex."} {"geneset":"GO_REGULATION_OF_CATION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CATION_CHANNEL_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of cation channel activity."} {"geneset":"GO_POSITIVE_REGULATION_OF_RECEPTOR_RECYCLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_RECEPTOR_RECYCLING","description":"Any process that activates or increases the frequency, rate or extent of receptor recycling."} {"geneset":"GO_RESPONSE_TO_MISFOLDED_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MISFOLDED_PROTEIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus."} {"geneset":"GO_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMEMBRANE_TRANSPORT","description":"The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other"} {"geneset":"GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC","description":"Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NEURON_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NEURON_DEATH","description":"Any process that stops, prevents or reduces the frequency, rate or extent of neuron death."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."} {"geneset":"GO_DEFENSE_RESPONSE_TO_FUNGUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEFENSE_RESPONSE_TO_FUNGUS","description":"Reactions triggered in response to the presence of a fungus that act to protect the cell or organism."} {"geneset":"GO_RIBONUCLEOSIDE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOSIDE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."} {"geneset":"GO_POSITIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING","description":"Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade."} {"geneset":"GO_REGULATION_OF_FILOPODIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FILOPODIUM_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."} {"geneset":"GO_REGULATION_OF_CELL_PROJECTION_SIZE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_PROJECTION_SIZE","description":"A process that modulates the size of a cell projection."} {"geneset":"GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_EXONUCLEOLYTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_EXONUCLEOLYTIC","description":"The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RYANODINE_SENSITIVE_CALCIUM_RELEASE_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RYANODINE_SENSITIVE_CALCIUM_RELEASE_CHANNEL_ACTIVITY","description":"Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY","description":"Any process that activates or increases the activity of the enzyme nitric-oxide synthase."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION","description":"Any process that activates or increases the frequency, rate or extent of cell cycle phase transition."} {"geneset":"GO_MYELOID_DENDRITIC_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_DENDRITIC_CELL_ACTIVATION","description":"The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."} {"geneset":"GO_MESONEPHROS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESONEPHROS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney."} {"geneset":"GO_EMBRYONIC_HEART_TUBE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_HEART_TUBE_MORPHOGENESIS","description":"The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart."} {"geneset":"GO_MESODERMAL_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESODERMAL_CELL_FATE_COMMITMENT","description":"The cell differentiation process that results in commitment of a cell to become part of the mesoderm."} {"geneset":"GO_REGULATION_OF_DENDRITE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DENDRITE_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of dendrite development."} {"geneset":"GO_RESPONSE_TO_LIGHT_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_LIGHT_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light."} {"geneset":"GO_UTP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UTP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate."} {"geneset":"GO_REGULATION_OF_AXONOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_AXONOGENESIS","description":"Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron."} {"geneset":"GO_RIBOSOMAL_SMALL_SUBUNIT_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOMAL_SMALL_SUBUNIT_ASSEMBLY","description":"The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit."} {"geneset":"GO_REGULATION_OF_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway."} {"geneset":"GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_HORMONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_HORMONE","description":"The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."} {"geneset":"GO_REGULATION_OF_NEUTROPHIL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUTROPHIL_MIGRATION","description":"Any process that modulates the frequency, rate or extent of neutrophil migration."} {"geneset":"GO_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus."} {"geneset":"GO_PENTOSE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PENTOSE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."} {"geneset":"GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE","description":"Any process that activates or increases the frequency, rate or extent of a defense response."} {"geneset":"GO_PHAGOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOCYTOSIS","description":"An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles."} {"geneset":"GO_BRANCHING_INVOLVED_IN_MAMMARY_GLAND_DUCT_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRANCHING_INVOLVED_IN_MAMMARY_GLAND_DUCT_MORPHOGENESIS","description":"The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."} {"geneset":"GO_ALKALOID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALKALOID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)."} {"geneset":"GO_POSITIVE_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_CELL_DEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_CELL_DEATH","description":"Any process that activates or increases the frequency, rate or extent of oxidative stress-induced cell death."} {"geneset":"GO_CENTROMERE_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTROMERE_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere."} {"geneset":"GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY","description":"Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity."} {"geneset":"GO_RRNA_CONTAINING_RIBONUCLEOPROTEIN_COMPLEX_EXPORT_FROM_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_CONTAINING_RIBONUCLEOPROTEIN_COMPLEX_EXPORT_FROM_NUCLEUS","description":"The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm."} {"geneset":"GO_MITOTIC_SISTER_CHROMATID_COHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_SISTER_CHROMATID_COHESION","description":"The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission."} {"geneset":"GO_KINETOCHORE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINETOCHORE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_GLUCOSE_IMPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_GLUCOSE_IMPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle."} {"geneset":"GO_GLUCOSE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOSE_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose."} {"geneset":"GO_REGULATION_OF_MYOBLAST_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MYOBLAST_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of myoblast proliferation."} {"geneset":"GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_ANTIGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_ANTIGEN","description":"The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex."} {"geneset":"GO_REGULATION_OF_CAMP_DEPENDENT_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CAMP_DEPENDENT_PROTEIN_KINASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE","description":"Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle."} {"geneset":"GO_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation."} {"geneset":"GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT","description":"A process in which an inorganic ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS","description":"Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_CYCLE","description":"Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity."} {"geneset":"GO_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation."} {"geneset":"GO_AXONAL_FASCICULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXONAL_FASCICULATION","description":"The collection of axons into a bundle of rods, known as a fascicle."} {"geneset":"GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS","description":"A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen."} {"geneset":"GO_REGULATION_OF_CAMP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CAMP_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."} {"geneset":"GO_REGULATION_OF_DEFENSE_RESPONSE_TO_BACTERIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEFENSE_RESPONSE_TO_BACTERIUM","description":"Any process that modulates the frequency, rate or extent of defense response to bacterium."} {"geneset":"GO_POSITIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION","description":"Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways."} {"geneset":"GO_FOLIC_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOLIC_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."} {"geneset":"GO_REGIONALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGIONALIZATION","description":"The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."} {"geneset":"GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."} {"geneset":"GO_RESPONSE_TO_WATER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_WATER","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water."} {"geneset":"GO_REGULATION_OF_CELL_KILLING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_KILLING","description":"Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism."} {"geneset":"GO_REGULATION_OF_ORGAN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ORGAN_MORPHOGENESIS","description":"Any process that modulates the frequency, rate or extent of organ morphogenesis."} {"geneset":"GO_REGULATION_OF_CARBOHYDRATE_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CARBOHYDRATE_CATABOLIC_PROCESS","description":"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates."} {"geneset":"GO_REGULATION_OF_RESPIRATORY_GASEOUS_EXCHANGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPIRATORY_GASEOUS_EXCHANGE","description":"Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment."} {"geneset":"GO_GLYCOSYL_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSYL_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of glycosyl compound."} {"geneset":"GO_CELLULAR_GLUCURONIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_GLUCURONIDATION","description":"The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor."} {"geneset":"GO_RESPONSE_TO_OXIDATIVE_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_OXIDATIVE_STRESS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."} {"geneset":"GO_REGULATION_OF_JUN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_JUN_KINASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of JUN kinase activity."} {"geneset":"GO_CEREBELLAR_PURKINJE_CELL_LAYER_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CEREBELLAR_PURKINJE_CELL_LAYER_DEVELOPMENT","description":"The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."} {"geneset":"GO_PHOSPHOLIPID_EFFLUX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_EFFLUX","description":"The directed movement of a phospholipid out of a cell or organelle."} {"geneset":"GO_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving mucopolysaccharide."} {"geneset":"GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."} {"geneset":"GO_TRNA_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_PROCESSING","description":"The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group."} {"geneset":"GO_REGULATION_OF_SYNAPSE_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPSE_MATURATION","description":"Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state."} {"geneset":"GO_REGULATION_OF_VASCULAR_PERMEABILITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VASCULAR_PERMEABILITY","description":"Any process that modulates the extent to which blood vessels can be pervaded by fluid."} {"geneset":"GO_RESPONSE_TO_MECHANICAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MECHANICAL_STIMULUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus."} {"geneset":"GO_SUBPALLIUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUBPALLIUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon."} {"geneset":"GO_SOMATIC_RECOMBINATION_OF_IMMUNOGLOBULIN_GENE_SEGMENTS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMATIC_RECOMBINATION_OF_IMMUNOGLOBULIN_GENE_SEGMENTS","description":"The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus."} {"geneset":"GO_B_CELL_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_B_CELL_RECEPTOR_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell."} {"geneset":"GO_RECEPTOR_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."} {"geneset":"GO_PYRIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base."} {"geneset":"GO_SIGNAL_PEPTIDE_PROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_PEPTIDE_PROCESSING","description":"The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell."} {"geneset":"GO_EPITHELIAL_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPITHELIAL_CELL_FATE_COMMITMENT","description":"The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell."} {"geneset":"GO_SODIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_ION_TRANSPORT","description":"The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2."} {"geneset":"GO_REGULATION_OF_CGMP_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CGMP_BIOSYNTHETIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP."} {"geneset":"GO_APOPTOTIC_MITOCHONDRIAL_CHANGES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APOPTOTIC_MITOCHONDRIAL_CHANGES","description":"The morphological and physiological alterations undergone by mitochondria during apoptosis."} {"geneset":"GO_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM","description":"The directed movement of proteins from the endoplasmic reticulum."} {"geneset":"GO_T_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_APOPTOTIC_PROCESS","description":"Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex."} {"geneset":"GO_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands."} {"geneset":"GO_REGULATION_OF_NECROPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NECROPTOTIC_PROCESS","description":"Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HEART_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HEART_GROWTH","description":"Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."} {"geneset":"GO_POSITIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of astrocyte differentiation."} {"geneset":"GO_SKELETAL_SYSTEM_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SKELETAL_SYSTEM_MORPHOGENESIS","description":"The process in which the anatomical structures of the skeleton are generated and organized."} {"geneset":"GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level."} {"geneset":"GO_LEUKOTRIENE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOTRIENE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid."} {"geneset":"GO_POSITIVE_REGULATION_OF_CHROMOSOME_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CHROMOSOME_SEGREGATION","description":"Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."} {"geneset":"GO_RRNA_METHYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_METHYLATION","description":"The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule."} {"geneset":"GO_GENE_SILENCING_BY_RNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GENE_SILENCING_BY_RNA","description":"Any process in which RNA molecules inactivate expression of target genes."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRIGLYCERIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRIGLYCERIDE_METABOLIC_PROCESS","description":"Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."} {"geneset":"GO_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate, or extent of endothelial cell proliferation."} {"geneset":"GO_REGULATED_EXOCYTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATED_EXOCYTOSIS","description":"A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand."} {"geneset":"GO_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES","description":"The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process."} {"geneset":"GO_TEMPERATURE_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TEMPERATURE_HOMEOSTASIS","description":"A homeostatic process in which an organism modulates its internal body temperature."} {"geneset":"GO_EMBRYONIC_CAMERA_TYPE_EYE_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_CAMERA_TYPE_EYE_FORMATION","description":"The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape."} {"geneset":"GO_PROTEIN_O_LINKED_GLYCOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_O_LINKED_GLYCOSYLATION","description":"A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan."} {"geneset":"GO_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative to initiate a change in cell activity."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RECEPTOR_BINDING","description":"Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor."} {"geneset":"GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION_GABAERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION_GABAERGIC","description":"Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."} {"geneset":"GO_DOPAMINE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOPAMINE_TRANSPORT","description":"The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."} {"geneset":"GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity."} {"geneset":"GO_CIRCULATORY_SYSTEM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CIRCULATORY_SYSTEM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis."} {"geneset":"GO_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_GLUCONEOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GLUCONEOGENESIS","description":"Any process that activates or increases the frequency, rate or extent of gluconeogenesis."} {"geneset":"GO_REGULATION_OF_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of cell proliferation."} {"geneset":"GO_EMBRYONIC_CAMERA_TYPE_EYE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_CAMERA_TYPE_EYE_DEVELOPMENT","description":"The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_EXECUTION_PHASE_OF_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_EXECUTION_PHASE_OF_APOPTOSIS","description":"Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis."} {"geneset":"GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION","description":"Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."} {"geneset":"GO_N_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_N_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION","description":"The alteration of the N-terminal amino acid residue in a protein."} {"geneset":"GO_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."} {"geneset":"GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_STABILIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_STABILIZATION","description":"The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage."} {"geneset":"GO_EMBRYONIC_PLACENTA_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_PLACENTA_MORPHOGENESIS","description":"The process in which the embryonic placenta is generated and organized."} {"geneset":"GO_DOPAMINE_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOPAMINE_RECEPTOR_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands."} {"geneset":"GO_REGULATION_OF_ERAD_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ERAD_PATHWAY","description":"Any process that modulates the frequency, rate or extent of ERAD pathway."} {"geneset":"GO_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BEHAVIOR","description":"The internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."} {"geneset":"GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT","description":"The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell."} {"geneset":"GO_MANNOSYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MANNOSYLATION","description":"The covalent attachment of a mannose residue to a substrate molecule."} {"geneset":"GO_DNA_REPLICATION_INDEPENDENT_NUCLEOSOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_REPLICATION_INDEPENDENT_NUCLEOSOME_ORGANIZATION","description":"The formation or destruction of chromatin structures, occurring outside the context of DNA replication."} {"geneset":"GO_AXON_EXTENSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXON_EXTENSION","description":"Long distance growth of a single axon process involved in cellular development."} {"geneset":"GO_DERMATAN_SULFATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DERMATAN_SULFATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues."} {"geneset":"GO_TRIVALENT_INORGANIC_CATION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRIVALENT_INORGANIC_CATION_TRANSPORT","description":"The directed movement of inorganic cations with a valency of three into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_TARGETING_TO_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_TARGETING_TO_MEMBRANE","description":"Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."} {"geneset":"GO_BILE_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BILE_ACID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine."} {"geneset":"GO_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport."} {"geneset":"GO_INNERVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNERVATION","description":"The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue."} {"geneset":"GO_RESPONSE_TO_VIRUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_VIRUS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus."} {"geneset":"GO_DEVELOPMENTAL_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENTAL_MATURATION","description":"A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state."} {"geneset":"GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS","description":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids."} {"geneset":"GO_ALCOHOL_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALCOHOL_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."} {"geneset":"GO_REGULATION_OF_INSULIN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INSULIN_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of insulin receptor signaling."} {"geneset":"GO_ADIPOSE_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADIPOSE_TISSUE_DEVELOPMENT","description":"The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat."} {"geneset":"GO_PYRIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof."} {"geneset":"GO_PROTEIN_TARGETING_TO_LYSOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TARGETING_TO_LYSOSOME","description":"The process of directing proteins towards the lysosome using signals contained within the protein."} {"geneset":"GO_ISOPRENOID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ISOPRENOID_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND","description":"Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand."} {"geneset":"GO_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE","description":"Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."} {"geneset":"GO_NEGATIVE_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process."} {"geneset":"GO_RESPONSE_TO_UV_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_UV_B","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm."} {"geneset":"GO_CELLULAR_RESPONSE_TO_DRUG","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_DRUG","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS","description":"Any process that modulates the frequency, rate or extent of response to DNA damage stimulus."} {"geneset":"GO_AUTOPHAGOSOME_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AUTOPHAGOSOME_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome."} {"geneset":"GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION","description":"Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels."} {"geneset":"GO_PROTEIN_AUTOPROCESSING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_AUTOPROCESSING","description":"Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein."} {"geneset":"GO_ERYTHROCYTE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERYTHROCYTE_DEVELOPMENT","description":"The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure."} {"geneset":"GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_ACYL_CHAIN_REMODELING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_ACYL_CHAIN_REMODELING","description":"Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains."} {"geneset":"GO_POLYOL_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYOL_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."} {"geneset":"GO_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION","description":"Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."} {"geneset":"GO_ENDODERMAL_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDODERMAL_CELL_FATE_COMMITMENT","description":"The cell differentiation process that results in commitment of a cell to become part of the endoderm."} {"geneset":"GO_MONOAMINE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOAMINE_TRANSPORT","description":"The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_RESPONSE_TO_STARVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_STARVATION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment."} {"geneset":"GO_REGULATION_OF_GTPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GTPASE_ACTIVITY","description":"Any process that modulates the rate of GTP hydrolysis by a GTPase."} {"geneset":"GO_POSITIVE_REGULATION_OF_CAMP_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CAMP_MEDIATED_SIGNALING","description":"Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response."} {"geneset":"GO_RESPONSE_TO_REDOX_STATE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_REDOX_STATE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."} {"geneset":"GO_REGULATION_OF_GLUCONEOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GLUCONEOGENESIS","description":"Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol."} {"geneset":"GO_POST_EMBRYONIC_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POST_EMBRYONIC_DEVELOPMENT","description":"The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development."} {"geneset":"GO_CELLULAR_DEFENSE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_DEFENSE_RESPONSE","description":"A defense response that is mediated by cells."} {"geneset":"GO_BIOLOGICAL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BIOLOGICAL_ADHESION","description":"The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions."} {"geneset":"GO_CORTICAL_CYTOSKELETON_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORTICAL_CYTOSKELETON_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane."} {"geneset":"GO_HORMONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HORMONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."} {"geneset":"GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus."} {"geneset":"GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER","description":"The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide."} {"geneset":"GO_UTERUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UTERUS_DEVELOPMENT","description":"The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure."} {"geneset":"GO_THYROID_GLAND_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THYROID_GLAND_DEVELOPMENT","description":"The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone."} {"geneset":"GO_DNA_REPLICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_REPLICATION","description":"The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA."} {"geneset":"GO_NEURAL_TUBE_PATTERNING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURAL_TUBE_PATTERNING","description":"The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube."} {"geneset":"GO_RESPONSE_TO_HISTAMINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_HISTAMINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter."} {"geneset":"GO_RESPONSE_TO_MANGANESE_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MANGANESE_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus."} {"geneset":"GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION","description":"Any process that modulates the frequency, rate or extent of sister chromatid segregation."} {"geneset":"GO_CELL_CYCLE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CYCLE_PROCESS","description":"The cellular process that ensures successive accurate and complete genome replication and chromosome segregation."} {"geneset":"GO_UNSATURATED_FATTY_ACID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UNSATURATED_FATTY_ACID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms."} {"geneset":"GO_POSITIVE_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS","description":"Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."} {"geneset":"GO_SIALYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIALYLATION","description":"The covalent attachment of sialic acid to a substrate molecule."} {"geneset":"GO_REGULATION_OF_GENE_SILENCING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GENE_SILENCING","description":"Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation."} {"geneset":"GO_POSITIVE_REGULATION_OF_AMINO_ACID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_AMINO_ACID_TRANSPORT","description":"Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_ENDOCRINE_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCRINE_PROCESS","description":"The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system."} {"geneset":"GO_PRIMARY_ALCOHOL_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRIMARY_ALCOHOL_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it."} {"geneset":"GO_PLATELET_AGGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_AGGREGATION","description":"The adhesion of one platelet to one or more other platelets via adhesion molecules."} {"geneset":"GO_TISSUE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TISSUE_DEVELOPMENT","description":"The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure."} {"geneset":"GO_RNA_INTERFERENCE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_INTERFERENCE","description":"The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes."} {"geneset":"GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION","description":"Any process that activates or increases the frequency, rate or extent of establishment of protein localization."} {"geneset":"GO_WALKING_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WALKING_BEHAVIOR","description":"The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg."} {"geneset":"GO_REGULATION_OF_TELOMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TELOMERASE_ACTIVITY","description":"Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence."} {"geneset":"GO_REGULATION_OF_CELL_AGING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_AGING","description":"Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan."} {"geneset":"GO_CELL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_GROWTH","description":"The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present."} {"geneset":"GO_COFACTOR_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COFACTOR_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein."} {"geneset":"GO_LYSINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_AXONOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_AXONOGENESIS","description":"Any process that activates or increases the frequency, rate or extent of axonogenesis."} {"geneset":"GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription."} {"geneset":"GO_CHAPERONE_MEDIATED_PROTEIN_FOLDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHAPERONE_MEDIATED_PROTEIN_FOLDING","description":"The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone."} {"geneset":"GO_POSITIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS","description":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids."} {"geneset":"GO_REGULATION_OF_LYMPHOCYTE_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_LYMPHOCYTE_MIGRATION","description":"Any process that modulates the frequency, rate or extent of lymphocyte migration."} {"geneset":"GO_BONE_MATURATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BONE_MATURATION","description":"A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state."} {"geneset":"GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION","description":"Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."} {"geneset":"GO_HEMOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEMOSTASIS","description":"The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part."} {"geneset":"GO_ZYMOGEN_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ZYMOGEN_ACTIVATION","description":"The proteolytic processing of an inactive enzyme to an active form."} {"geneset":"GO_AZOLE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AZOLE_TRANSPORT","description":"The directed movement of azoles, heterocyclic compounds found in many biologically important substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_CELLULAR_MACROMOLECULAR_COMPLEX_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_MACROMOLECULAR_COMPLEX_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION","description":"Any process that decreases the concentration of calcium ions in the cytosol."} {"geneset":"GO_POSITIVE_REGULATION_OF_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PHOSPHATASE_ACTIVITY","description":"Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."} {"geneset":"GO_LYMPHOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYMPHOCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin."} {"geneset":"GO_REGULATION_OF_POTASSIUM_ION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_POTASSIUM_ION_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_CELLULAR_RESPONSE_TO_OXIDATIVE_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_OXIDATIVE_STRESS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."} {"geneset":"GO_NEURAL_CREST_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURAL_CREST_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell."} {"geneset":"GO_ACTIVATION_OF_ANAPHASE_PROMOTING_COMPLEX_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_ANAPHASE_PROMOTING_COMPLEX_ACTIVITY","description":"Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex."} {"geneset":"GO_CALCIUM_ION_IMPORT_INTO_CYTOSOL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ION_IMPORT_INTO_CYTOSOL","description":"The directed movement of calcium ion into a cytosol."} {"geneset":"GO_MICROTUBULE_POLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_POLYMERIZATION","description":"The addition of tubulin heterodimers to one or both ends of a microtubule."} {"geneset":"GO_POSITIVE_REGULATION_OF_MYELINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MYELINATION","description":"Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons."} {"geneset":"GO_SPLICEOSOMAL_SNRNP_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPLICEOSOMAL_SNRNP_ASSEMBLY","description":"The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome."} {"geneset":"GO_OLIGOSACCHARIDE_LIPID_INTERMEDIATE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLIGOSACCHARIDE_LIPID_INTERMEDIATE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation."} {"geneset":"GO_MONOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOCYTE_DIFFERENTIATION","description":"The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte."} {"geneset":"GO_REGULATION_OF_GONADOTROPIN_SECRETION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_GONADOTROPIN_SECRETION","description":"Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin."} {"geneset":"GO_RESPONSE_TO_LAMINAR_FLUID_SHEAR_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_LAMINAR_FLUID_SHEAR_STRESS","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls."} {"geneset":"GO_RESPONSE_TO_LEAD_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_LEAD_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus."} {"geneset":"GO_DEFENSE_RESPONSE_TO_BACTERIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEFENSE_RESPONSE_TO_BACTERIUM","description":"Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism."} {"geneset":"GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL_BY_SARCOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL_BY_SARCOPLASMIC_RETICULUM","description":"Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels."} {"geneset":"GO_NUCLEOTIDE_SALVAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_SALVAGE","description":"Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis."} {"geneset":"GO_ALCOHOL_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALCOHOL_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."} {"geneset":"GO_MYELOID_DENDRITIC_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELOID_DENDRITIC_CELL_DIFFERENTIATION","description":"The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin."} {"geneset":"GO_CELLULAR_METABOLIC_COMPOUND_SALVAGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_METABOLIC_COMPOUND_SALVAGE","description":"Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells."} {"geneset":"GO_COPULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COPULATION","description":"The act of sexual union between male and female, involving the transfer of sperm."} {"geneset":"GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of cation transmembrane transport."} {"geneset":"GO_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL","description":"Any process that modulates the frequency, rate or extent of viral release from host cell."} {"geneset":"GO_NEPHRIC_DUCT_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEPHRIC_DUCT_MORPHOGENESIS","description":"The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney."} {"geneset":"GO_POSITIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS","description":"Any process that activates or increases the frequency, rate or extent of transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane."} {"geneset":"GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT","description":"Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."} {"geneset":"GO_ESTROGEN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTROGEN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."} {"geneset":"GO_IRON_ION_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IRON_ION_HOMEOSTASIS","description":"Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell."} {"geneset":"GO_PROTEOLYSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEOLYSIS","description":"The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds."} {"geneset":"GO_SYNAPSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPSIS","description":"The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Synapsis begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete."} {"geneset":"GO_ORGANELLE_DISASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_DISASSEMBLY","description":"The disaggregation of an organelle into its constituent components."} {"geneset":"GO_REGULATION_OF_ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT","description":"Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi."} {"geneset":"GO_RESPONSE_TO_IRON_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_IRON_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING","description":"A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions."} {"geneset":"GO_LOCOMOTORY_EXPLORATION_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOCOMOTORY_EXPLORATION_BEHAVIOR","description":"The specific movement from place to place of an organism in response to a novel environment."} {"geneset":"GO_PYRIMIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIMIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."} {"geneset":"GO_NUCLEAR_CHROMOSOME_SEGREGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_CHROMOSOME_SEGREGATION","description":"The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles."} {"geneset":"GO_AUDITORY_RECEPTOR_CELL_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AUDITORY_RECEPTOR_CELL_MORPHOGENESIS","description":"Any process that alters the size or shape of an auditory receptor cell."} {"geneset":"GO_REGULATION_OF_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH","description":"Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates."} {"geneset":"GO_REGULATION_OF_WNT_SIGNALING_PATHWAY_PLANAR_CELL_POLARITY_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_WNT_SIGNALING_PATHWAY_PLANAR_CELL_POLARITY_PATHWAY","description":"Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway."} {"geneset":"GO_NEUROTROPHIN_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTROPHIN_SIGNALING_PATHWAY","description":"A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons."} {"geneset":"GO_CELLULAR_RESPONSE_TO_INTERFERON_BETA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_INTERFERON_BETA","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon."} {"geneset":"GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_CYTOCHROME_C_TO_OXYGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_CYTOCHROME_C_TO_OXYGEN","description":"The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV."} {"geneset":"GO_NEGATIVE_REGULATION_OF_VIRAL_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_VIRAL_TRANSCRIPTION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription."} {"geneset":"GO_FILOPODIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FILOPODIUM_ASSEMBLY","description":"The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."} {"geneset":"GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure."} {"geneset":"GO_STABILIZATION_OF_MEMBRANE_POTENTIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STABILIZATION_OF_MEMBRANE_POTENTIAL","description":"The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."} {"geneset":"GO_ERK1_AND_ERK2_CASCADE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ERK1_AND_ERK2_CASCADE","description":"An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell."} {"geneset":"GO_LENS_FIBER_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LENS_FIBER_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."} {"geneset":"GO_SYNCYTIUM_FORMATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNCYTIUM_FORMATION","description":"The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division."} {"geneset":"GO_POSITIVE_REGULATION_OF_MESONEPHROS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MESONEPHROS_DEVELOPMENT","description":"Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."} {"geneset":"GO_GLYCOSIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSIDE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound."} {"geneset":"GO_HYDROGEN_ION_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROGEN_ION_TRANSMEMBRANE_TRANSPORT","description":"The directed movement of hydrogen ion (proton) across a membrane."} {"geneset":"GO_HETEROTYPIC_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HETEROTYPIC_CELL_CELL_ADHESION","description":"The attachment of a cell to a cell of a different type via adhesion molecules."} {"geneset":"GO_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion."} {"geneset":"GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_APOPTOTIC_PROCESS","description":"Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process."} {"geneset":"GO_PROSTANOID_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROSTANOID_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure."} {"geneset":"GO_POSITIVE_REGULATION_OF_ERAD_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ERAD_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of ERAD pathway."} {"geneset":"GO_CENTROSOME_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTROSOME_LOCALIZATION","description":"Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell."} {"geneset":"GO_ASTROCYTE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASTROCYTE_DEVELOPMENT","description":"The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."} {"geneset":"GO_RESPONSE_TO_MONOAMINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MONOAMINE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan."} {"geneset":"GO_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN","description":"The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."} {"geneset":"GO_METAPHASE_PLATE_CONGRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METAPHASE_PLATE_CONGRESSION","description":"The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle."} {"geneset":"GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation."} {"geneset":"GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_NFAT_PROTEIN_IMPORT_INTO_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_NFAT_PROTEIN_IMPORT_INTO_NUCLEUS","description":"Any process that activates or increases the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus."} {"geneset":"GO_RESPONSE_TO_HYDROGEN_PEROXIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_HYDROGEN_PEROXIDE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus."} {"geneset":"GO_REGULATION_OF_DEVELOPMENTAL_PIGMENTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DEVELOPMENTAL_PIGMENTATION","description":"Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism."} {"geneset":"GO_EXTRACELLULAR_FIBRIL_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_FIBRIL_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of extracellular fibrils, extracellular matrix material consisting of polysaccharides and/or proteins."} {"geneset":"GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_APOPTOTIC_PROCESS","description":"Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."} {"geneset":"GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar."} {"geneset":"GO_POSITIVE_REGULATION_OF_ANION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ANION_TRANSPORT","description":"Any process that activates or increases the frequency, rate or extent of anion transport."} {"geneset":"GO_INNER_EAR_RECEPTOR_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNER_EAR_RECEPTOR_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."} {"geneset":"GO_REGULATION_OF_MONOCYTE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_MONOCYTE_CHEMOTAXIS","description":"Any process that modulates the frequency, rate, or extent of monocyte chemotaxis."} {"geneset":"GO_PEPTIDE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_TRANSPORT","description":"The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_T_CELL_SELECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_SELECTION","description":"The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation."} {"geneset":"GO_NEGATIVE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_CHEMOTAXIS","description":"The directed movement of a motile cell or organism towards a lower concentration of a chemical."} {"geneset":"GO_PHAGOCYTOSIS_RECOGNITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOCYTOSIS_RECOGNITION","description":"The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell."} {"geneset":"GO_MISFOLDED_OR_INCOMPLETELY_SYNTHESIZED_PROTEIN_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MISFOLDED_OR_INCOMPLETELY_SYNTHESIZED_PROTEIN_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins."} {"geneset":"GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN","description":"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin."} {"geneset":"GO_POST_EMBRYONIC_ORGAN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POST_EMBRYONIC_ORGAN_DEVELOPMENT","description":"Development, taking place during the post-embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."} {"geneset":"GO_DEVELOPMENTAL_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENTAL_GROWTH","description":"The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another."} {"geneset":"GO_REGULATION_OF_PROTEIN_TARGETING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_TARGETING","description":"Any process that modulates the frequency, rate or extent of protein targeting."} {"geneset":"GO_THYROID_HORMONE_GENERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THYROID_HORMONE_GENERATION","description":"The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones."} {"geneset":"GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL","description":"The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine."} {"geneset":"GO_CENTRAL_NERVOUS_SYSTEM_NEURON_AXONOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTRAL_NERVOUS_SYSTEM_NEURON_AXONOGENESIS","description":"Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells."} {"geneset":"GO_V_D_J_RECOMBINATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_V_D_J_RECOMBINATION","description":"The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."} {"geneset":"GO_METANEPHROS_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METANEPHROS_MORPHOGENESIS","description":"The process in which the anatomical structures of the metanephros are generated and organized."} {"geneset":"GO_GLYCOPROTEIN_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOPROTEIN_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."} {"geneset":"GO_POSITIVE_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS","description":"Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus."} {"geneset":"GO_SINGLE_ORGANISM_CELLULAR_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_ORGANISM_CELLULAR_LOCALIZATION","description":"A cellular localization which involves only one organism."} {"geneset":"GO_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE","description":"The process in which the anatomical structure of the retina is generated and organized."} {"geneset":"GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN","description":"The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell."} {"geneset":"GO_HISTONE_H3_DEACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_H3_DEACETYLATION","description":"The modification of histone H3 by the removal of one or more acetyl groups."} {"geneset":"GO_REGULATION_OF_SYNAPTIC_VESICLE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPTIC_VESICLE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of synaptic vesicle transport."} {"geneset":"GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation."} {"geneset":"GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION","description":"Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."} {"geneset":"GO_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE","description":"The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances."} {"geneset":"GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway."} {"geneset":"GO_POSITIVE_REGULATION_OF_MACROPHAGE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_MACROPHAGE_DIFFERENTIATION","description":"Any process that activates or increases the frequency, rate or extent of macrophage differentiation."} {"geneset":"GO_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES","description":"Any process that modulates the frequency, rate or extent of response to reactive oxygen species."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells."} {"geneset":"GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM","description":"A circulatory process that occurs at the level of the vasculature."} {"geneset":"GO_MULTI_ORGANISM_BEHAVIOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTI_ORGANISM_BEHAVIOR","description":"Any process in which an organism has a behavioral effect on another organism of the same or different species."} {"geneset":"GO_REGULATION_OF_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY","description":"Any process that modulates the frequency, rate or extent of tight junction assembly."} {"geneset":"GO_DNA_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_METABOLIC_PROCESS","description":"Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."} {"geneset":"GO_INTESTINAL_ABSORPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTESTINAL_ABSORPTION","description":"Any process in which nutrients are taken up from the contents of the intestine."} {"geneset":"GO_MALE_SEX_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MALE_SEX_DIFFERENTIATION","description":"The establishment of the sex of a male organism by physical differentiation."} {"geneset":"GO_REGULATION_OF_SKELETAL_MUSCLE_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SKELETAL_MUSCLE_CELL_PROLIFERATION","description":"Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_KERATINOCYTE_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_KERATINOCYTE_PROLIFERATION","description":"Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."} {"geneset":"GO_LAMELLIPODIUM_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAMELLIPODIUM_ASSEMBLY","description":"Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."} {"geneset":"GO_RESPONSE_TO_WATER_DEPRIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_WATER_DEPRIVATION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water."} {"geneset":"GO_MITOTIC_CHROMOSOME_CONDENSATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_CHROMOSOME_CONDENSATION","description":"The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells."} {"geneset":"GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS","description":"A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."} {"geneset":"GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT","description":"Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."} {"geneset":"GO_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","description":"Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."} {"geneset":"GO_DNA_ALKYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_ALKYLATION","description":"The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis."} {"geneset":"GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS","description":"Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress."} {"geneset":"GO_RENAL_SYSTEM_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RENAL_SYSTEM_PROCESS","description":"A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)."} {"geneset":"GO_LEUKOCYTE_HOMEOSTASIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUKOCYTE_HOMEOSTASIS","description":"The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus."} {"geneset":"GO_POSITIVE_REGULATION_OF_ORGANELLE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ORGANELLE_ASSEMBLY","description":"Any process that activates or increases the frequency, rate or extent of organelle assembly."} {"geneset":"GO_LUNG_ALVEOLUS_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LUNG_ALVEOLUS_DEVELOPMENT","description":"The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways."} {"geneset":"GO_PROGESTERONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROGESTERONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."} {"geneset":"GO_SPLEEN_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPLEEN_DEVELOPMENT","description":"The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions."} {"geneset":"GO_RHO_PROTEIN_SIGNAL_TRANSDUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RHO_PROTEIN_SIGNAL_TRANSDUCTION","description":"A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state."} {"geneset":"GO_RESPONSE_TO_LEPTIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_LEPTIN","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism]."} {"geneset":"GO_NEUROPEPTIDE_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROPEPTIDE_SIGNALING_PATHWAY","description":"The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor."} {"geneset":"GO_ACTIVATION_OF_PROTEIN_KINASE_A_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_PROTEIN_KINASE_A_ACTIVITY","description":"Any process that initiates the activity of the inactive enzyme protein kinase A."} {"geneset":"GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION","description":"Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor."} {"geneset":"GO_AMP_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMP_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving AMP, adenosine monophosphate."} {"geneset":"GO_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS","description":"The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion."} {"geneset":"GO_NEGATIVE_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation."} {"geneset":"GO_REGULATION_OF_RNA_SPLICING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_RNA_SPLICING","description":"Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA."} {"geneset":"GO_REGULATION_OF_BLOOD_CIRCULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_BLOOD_CIRCULATION","description":"Any process that modulates the frequency, rate or extent of blood circulation."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION","description":"Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."} {"geneset":"GO_NEGATIVE_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING","description":"Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading."} {"geneset":"GO_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS","description":"The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase."} {"geneset":"GO_CELLULAR_PROTEIN_COMPLEX_LOCALIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_PROTEIN_COMPLEX_LOCALIZATION","description":"A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell."} {"geneset":"GO_CELLULAR_RESPONSE_TO_GONADOTROPIN_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_GONADOTROPIN_STIMULUS","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus."} {"geneset":"GO_REGULATION_OF_HISTONE_H3_K9_ACETYLATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_HISTONE_H3_K9_ACETYLATION","description":"Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation."} {"geneset":"GO_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY","description":"Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription)."} {"geneset":"GO_NEGATIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."} {"geneset":"GO_CARDIAC_CELL_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CELL_DEVELOPMENT","description":"The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual."} {"geneset":"GO_REGULATION_OF_EXECUTION_PHASE_OF_APOPTOSIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_EXECUTION_PHASE_OF_APOPTOSIS","description":"Any process that modulates the frequency, rate or extent of execution phase of apoptosis."} {"geneset":"GO_RESPONSE_TO_CALCIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_CALCIUM_ION","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus."} {"geneset":"GO_NEGATIVE_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."} {"geneset":"GO_REGULATION_OF_INTERLEUKIN_12_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_INTERLEUKIN_12_PRODUCTION","description":"Any process that modulates the frequency, rate, or extent of interleukin-12 production."} {"geneset":"GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION","description":"Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter."} {"geneset":"GO_POSITIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION_INVOLVED_IN_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION_INVOLVED_IN_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_SIGNALING_PATHWAY","description":"Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G-protein coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol."} {"geneset":"GO_INNER_EAR_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNER_EAR_MORPHOGENESIS","description":"The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively."} {"geneset":"GO_RESPONSE_TO_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_ACTIVITY","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus."} {"geneset":"GO_ESTROUS_CYCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTROUS_CYCLE","description":"A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur."} {"geneset":"GO_ORGANELLE_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_FUSION","description":"The creation of a single organelle from two or more organelles."} {"geneset":"GO_REGULATION_OF_PROTEIN_PHOSPHATASE_TYPE_2A_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PROTEIN_PHOSPHATASE_TYPE_2A_ACTIVITY","description":"Any process that modulates the activity of the enzyme protein phosphatase type 2A."} {"geneset":"GO_STEROID_CATABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_CATABOLIC_PROCESS","description":"The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."} {"geneset":"GO_REGULATION_OF_CELL_FATE_COMMITMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_FATE_COMMITMENT","description":"Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."} {"geneset":"GO_REGULATION_OF_CELL_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_CELL_MORPHOGENESIS","description":"Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized."} {"geneset":"GO_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_RESULTING_IN_TRANSCRIPTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_RESULTING_IN_TRANSCRIPTION","description":"A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription."} {"geneset":"GO_ACUTE_PHASE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACUTE_PHASE_RESPONSE","description":"An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals."} {"geneset":"GO_POSITIVE_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY","description":"Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","description":"Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity."} {"geneset":"GO_S_ADENOSYLHOMOCYSTEINE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_S_ADENOSYLHOMOCYSTEINE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine."} {"geneset":"GO_CELLULAR_RESPONSE_TO_ALKALOID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELLULAR_RESPONSE_TO_ALKALOID","description":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active."} {"geneset":"GO_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY","description":"Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins."} {"geneset":"GO_MYOBLAST_FUSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOBLAST_FUSION","description":"A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."} {"geneset":"GO_TRNA_MODIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_MODIFICATION","description":"The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically."} {"geneset":"GO_CYTOSOLIC_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSOLIC_TRANSPORT","description":"The directed movement of substances or organelles within the cytosol."} {"geneset":"GO_INOSITOL_LIPID_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_LIPID_MEDIATED_SIGNALING","description":"A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids."} {"geneset":"GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_DEPOLYMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_DEPOLYMERIZATION","description":"Any process that activates or increases the frequency, rate or extent of actin depolymerization."} {"geneset":"GO_DNA_CATABOLIC_PROCESS_ENDONUCLEOLYTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_CATABOLIC_PROCESS_ENDONUCLEOLYTIC","description":"The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides."} {"geneset":"GO_POSITIVE_REGULATION_OF_GLIOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GLIOGENESIS","description":"Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia."} {"geneset":"GO_LACTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LACTATION","description":"The secretion of milk by the mammary gland."} {"geneset":"GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus."} {"geneset":"GO_REGULATION_OF_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY","description":"Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."} {"geneset":"GO_REGULATION_OF_NEUTROPHIL_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_NEUTROPHIL_CHEMOTAXIS","description":"Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."} {"geneset":"GO_MRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter."} {"geneset":"GO_EMBRYO_IMPLANTATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EMBRYO_IMPLANTATION","description":"Attachment of the blastocyst to the uterine lining."} {"geneset":"GO_RECEPTOR_CLUSTERING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_CLUSTERING","description":"The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response."} {"geneset":"GO_PIGMENT_ACCUMULATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIGMENT_ACCUMULATION","description":"The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus."} {"geneset":"GO_FATTY_ACID_ELONGATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_ELONGATION","description":"The elongation of a fatty acid chain by the sequential addition of two-carbon units."} {"geneset":"GO_CYTOSKELETON_DEPENDENT_CYTOKINESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSKELETON_DEPENDENT_CYTOKINESIS","description":"A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton."} {"geneset":"GO_QUINONE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_QUINONE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving quinone."} {"geneset":"GO_FLUID_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FLUID_TRANSPORT","description":"The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."} {"geneset":"GO_SYNAPSE_ASSEMBLY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPSE_ASSEMBLY","description":"The aggregation, arrangement and bonding together of a set of components to form a synapse."} {"geneset":"GO_PIGMENT_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIGMENT_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin."} {"geneset":"GO_IMMUNE_EFFECTOR_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNE_EFFECTOR_PROCESS","description":"Any process of the immune system that can potentially contribute to an immune response."} {"geneset":"GO_ODONTOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ODONTOGENESIS","description":"The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food."} {"geneset":"GO_CORPUS_CALLOSUM_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORPUS_CALLOSUM_DEVELOPMENT","description":"The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres."} {"geneset":"GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_DOPAMINERGIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_DOPAMINERGIC","description":"Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION","description":"Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."} {"geneset":"GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity."} {"geneset":"GO_NUCLEOBASE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOBASE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid."} {"geneset":"GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation."} {"geneset":"GO_GOLGI_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus."} {"geneset":"GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION","description":"Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."} {"geneset":"GO_REGULATION_OF_OSSIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_OSSIFICATION","description":"Any process that modulates the frequency, rate or extent of bone formation."} {"geneset":"GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION","description":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite."} {"geneset":"GO_DIVALENT_INORGANIC_CATION_TRANSPORT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIVALENT_INORGANIC_CATION_TRANSPORT","description":"The directed movement of inorganic cations with a valency of two into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage."} {"geneset":"GO_B_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_B_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE","description":"The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."} {"geneset":"GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER","description":"Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter."} {"geneset":"GO_NEGATIVE_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS","description":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."} {"geneset":"GO_PROTEIN_HETEROOLIGOMERIZATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HETEROOLIGOMERIZATION","description":"The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."} {"geneset":"GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY","description":"Any process that modulates the frequency, rate or extent of apoptotic signaling pathway."} {"geneset":"GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_REGULATION_OF_GENE_EXPRESSION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_REGULATION_OF_GENE_EXPRESSION","description":"Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another."} {"geneset":"GO_ACTIVATION_OF_MAPKK_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATION_OF_MAPKK_ACTIVITY","description":"The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK)."} {"geneset":"GO_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION","description":"The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland."} {"geneset":"GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL","description":"Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal."} {"geneset":"GO_NEGATIVE_REGULATION_OF_CELL_PROLIFERATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_CELL_PROLIFERATION","description":"Any process that stops, prevents or reduces the rate or extent of cell proliferation."} {"geneset":"GO_REGULATION_OF_T_CELL_MIGRATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_T_CELL_MIGRATION","description":"Any process that modulates the frequency, rate or extent of T cell migration."} {"geneset":"GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY","description":"Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity."} {"geneset":"GO_CAMP_MEDIATED_SIGNALING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CAMP_MEDIATED_SIGNALING","description":"Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell."} {"geneset":"GO_POSITIVE_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS","description":"Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose."} {"geneset":"GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE","description":"Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response."} {"geneset":"GO_PROTEIN_TARGETING_TO_MITOCHONDRION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TARGETING_TO_MITOCHONDRION","description":"The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein."} {"geneset":"GO_POSITIVE_REGULATION_OF_OSSIFICATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_REGULATION_OF_OSSIFICATION","description":"Any process that activates or increases the frequency, rate or extent of bone formation."} {"geneset":"GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."} {"geneset":"GO_REGULATION_OF_VASCULATURE_DEVELOPMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_VASCULATURE_DEVELOPMENT","description":"Any process that modulates the frequency, rate or extent of vasculature development."} {"geneset":"GO_DETECTION_OF_CALCIUM_ION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DETECTION_OF_CALCIUM_ION","description":"The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal."} {"geneset":"GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_ENDONUCLEOLYTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_ENDONUCLEOLYTIC","description":"The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides."} {"geneset":"GO_FRUCTOSE_METABOLIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FRUCTOSE_METABOLIC_PROCESS","description":"The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey."} {"geneset":"GO_EYE_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EYE_MORPHOGENESIS","description":"The process in which the anatomical structures of the eye are generated and organized."} {"geneset":"GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION","description":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production."} {"geneset":"GO_POSITIVE_CHEMOTAXIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSITIVE_CHEMOTAXIS","description":"The directed movement of a motile cell or organism towards a higher concentration of a chemical."} {"geneset":"GO_NEGATIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME","description":"Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism."} {"geneset":"GO_RESPONSE_TO_NITRIC_OXIDE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPONSE_TO_NITRIC_OXIDE","description":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus."} {"geneset":"GO_HEAD_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEAD_MORPHOGENESIS","description":"The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body."} {"geneset":"GO_REGULATION_OF_FATTY_ACID_BETA_OXIDATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_FATTY_ACID_BETA_OXIDATION","description":"Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation."} {"geneset":"GO_REGULATION_OF_STEM_CELL_DIFFERENTIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_STEM_CELL_DIFFERENTIATION","description":"Any process that modulates the frequency, rate or extent of stem cell differentiation."} {"geneset":"GO_BRAIN_MORPHOGENESIS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRAIN_MORPHOGENESIS","description":"The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)."} {"geneset":"GO_AMINE_BIOSYNTHETIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINE_BIOSYNTHETIC_PROCESS","description":"The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."} {"geneset":"GO_FILOPODIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FILOPODIUM","description":"Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft."} {"geneset":"GO_NUCLEAR_CHROMOSOME_TELOMERIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_CHROMOSOME_TELOMERIC_REGION","description":"The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins."} {"geneset":"GO_CLATHRIN_SCULPTED_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_SCULPTED_VESICLE","description":"A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release."} {"geneset":"GO_I_BAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_I_BAND","description":"A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end."} {"geneset":"GO_AGGRESOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AGGRESOME","description":"An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules."} {"geneset":"GO_MULTIVESICULAR_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MULTIVESICULAR_BODY","description":"A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm."} {"geneset":"GO_RNA_CAP_BINDING_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_CAP_BINDING_COMPLEX","description":"Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA."} {"geneset":"GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE","description":"A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver."} {"geneset":"GO_EXTRACELLULAR_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_MATRIX","description":"A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals and bacteria) or be part of the cell (as in plants)."} {"geneset":"GO_PHAGOCYTIC_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOCYTIC_VESICLE","description":"A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis."} {"geneset":"GO_ENDOLYSOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOLYSOSOME","description":"An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place."} {"geneset":"GO_90S_PRERIBOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_90S_PRERIBOSOME","description":"A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins."} {"geneset":"GO_CYTOCHROME_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOCHROME_COMPLEX","description":"A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions."} {"geneset":"GO_CHROMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME","description":"A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information."} {"geneset":"GO_CONDENSED_NUCLEAR_CHROMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONDENSED_NUCLEAR_CHROMOSOME","description":"A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome."} {"geneset":"GO_NUCLEAR_ENVELOPE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_ENVELOPE","description":"The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)."} {"geneset":"GO_RETROMER_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETROMER_COMPLEX","description":"A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35."} {"geneset":"GO_PROTEASOME_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEASOME_COMPLEX","description":"A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core."} {"geneset":"GO_NUCLEAR_EXOSOME_RNASE_COMPLEX_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_EXOSOME_RNASE_COMPLEX_","description":"Complex of 3'-5' exoribonucleases found in the nucleus."} {"geneset":"GO_ER_TO_GOLGI_TRANSPORT_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ER_TO_GOLGI_TRANSPORT_VESICLE","description":"A vesicle that mediates transport from the endoplasmic reticulum to the Golgi complex; bears a coat formed of the COPII coat complex proteins; such vesicles found associated with endoplasmic reticulum (ER) membranes at steady state, and are involved in ER to Golgi (anterograde) vesicle transport."} {"geneset":"GO_TRANSCRIPTION_FACTOR_TFIID_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_TFIID_COMPLEX","description":"A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters."} {"geneset":"GO_CENTRIOLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTRIOLE","description":"A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle."} {"geneset":"GO_MICROTUBULE_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_CYTOSKELETON","description":"The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins."} {"geneset":"GO_LYSOSOMAL_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSOSOMAL_LUMEN","description":"The volume enclosed within the lysosomal membrane."} {"geneset":"GO_PRE_AUTOPHAGOSOMAL_STRUCTURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRE_AUTOPHAGOSOMAL_STRUCTURE","description":"A punctate structure localized in the vicinity of the vacuole that is required for the formation of autophagosomes."} {"geneset":"GO_CELL_CELL_CONTACT_ZONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_CONTACT_ZONE","description":"Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle."} {"geneset":"GO_MUSCLE_MYOSIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MUSCLE_MYOSIN_COMPLEX","description":"A filament of myosin found in a muscle cell of any type."} {"geneset":"GO_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX","description":"A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential."} {"geneset":"GO_INFLAMMASOME_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INFLAMMASOME_COMPLEX","description":"A cytosolic protein complex that is capable of activating caspase-1."} {"geneset":"GO_IMMUNOLOGICAL_SYNAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNOLOGICAL_SYNAPSE","description":"An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction."} {"geneset":"GO_GABA_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GABA_RECEPTOR_COMPLEX","description":"A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_TUBULAR_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_TUBULAR_NETWORK","description":"A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section."} {"geneset":"GO_FILOPODIUM_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FILOPODIUM_MEMBRANE","description":"The portion of the plasma membrane surrounding a filopodium."} {"geneset":"GO_PHOSPHATASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATASE_COMPLEX","description":"A protein complex which is capable of phosphatase activity."} {"geneset":"GO_TRANSCRIPTION_EXPORT_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_EXPORT_COMPLEX","description":"The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans."} {"geneset":"GO_SPERM_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERM_PART","description":"Any constituent part of a sperm, a mature male germ cell that develops from a spermatid."} {"geneset":"GO_U1_SNRNP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_U1_SNRNP","description":"A ribonucleoprotein complex that contains small nuclear RNA U1."} {"geneset":"GO_ANCHORED_COMPONENT_OF_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANCHORED_COMPONENT_OF_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE","description":"The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping."} {"geneset":"GO_NUCLEOID","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOID","description":"The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined."} {"geneset":"GO_KINESIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINESIN_COMPLEX","description":"Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work."} {"geneset":"GO_HOLO_TFIIH_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOLO_TFIIH_COMPLEX","description":"A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex."} {"geneset":"GO_BASOLATERAL_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASOLATERAL_PLASMA_MEMBRANE","description":"The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis."} {"geneset":"GO_NUCLEAR_OUTER_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_OUTER_MEMBRANE","description":"The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes."} {"geneset":"GO_CATION_TRANSPORTING_ATPASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_TRANSPORTING_ATPASE_COMPLEX","description":"Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in)."} {"geneset":"GO_CYTOPLASMIC_STRESS_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_STRESS_GRANULE","description":"A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress."} {"geneset":"GO_SECRETORY_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECRETORY_GRANULE","description":"A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_OUTER_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_OUTER_MEMBRANE","description":"The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane."} {"geneset":"GO_OXIDOREDUCTASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_COMPLEX","description":"Any protein complex that possesses oxidoreductase activity."} {"geneset":"GO_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding any membrane-bounded vesicle in the cell."} {"geneset":"GO_SAGA_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SAGA_COMPLEX","description":"A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery."} {"geneset":"GO_CYTOPLASMIC_UBIQUITIN_LIGASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_UBIQUITIN_LIGASE_COMPLEX","description":"A ubiquitin ligase complex found in the cytoplasm."} {"geneset":"GO_AUTOPHAGOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AUTOPHAGOSOME","description":"A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the vacuole/lysosome for degradation as part of macroautophagy."} {"geneset":"GO_LARGE_RIBOSOMAL_SUBUNIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LARGE_RIBOSOMAL_SUBUNIT","description":"The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site)."} {"geneset":"GO_H4_HISTONE_ACETYLTRANSFERASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_H4_HISTONE_ACETYLTRANSFERASE_COMPLEX","description":"A protein complex which is capable of H4 histone acetyltransferase activity."} {"geneset":"GO_ZYMOGEN_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ZYMOGEN_GRANULE","description":"A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme."} {"geneset":"GO_TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell."} {"geneset":"GO_ENDOSOME_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOSOME_LUMEN","description":"The volume enclosed by the membrane of an endosome."} {"geneset":"GO_INTERCALATED_DISC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERCALATED_DISC","description":"A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells."} {"geneset":"GO_LATE_ENDOSOME_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LATE_ENDOSOME_MEMBRANE","description":"The lipid bilayer surrounding a late endosome."} {"geneset":"GO_EXCITATORY_SYNAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXCITATORY_SYNAPSE","description":"A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell."} {"geneset":"GO_TRANSFERASE_COMPLEX_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_COMPLEX_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS","description":"A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)."} {"geneset":"GO_CHROMOSOME_CENTROMERIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_CENTROMERIC_REGION","description":"The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome."} {"geneset":"GO_DNA_POLYMERASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_POLYMERASE_COMPLEX","description":"A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA."} {"geneset":"GO_PLATELET_ALPHA_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_ALPHA_GRANULE","description":"A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG)."} {"geneset":"GO_TELOMERASE_HOLOENZYME_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERASE_HOLOENZYME_COMPLEX","description":"Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_ORGANELLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_ORGANELLE_MEMBRANE","description":"The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane."} {"geneset":"GO_ADA2_GCN5_ADA3_TRANSCRIPTION_ACTIVATOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADA2_GCN5_ADA3_TRANSCRIPTION_ACTIVATOR_COMPLEX","description":"A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues."} {"geneset":"GO_SARCOPLASMIC_RETICULUM_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SARCOPLASMIC_RETICULUM_MEMBRANE","description":"The lipid bilayer surrounding the sarcoplasmic reticulum."} {"geneset":"GO_U2_TYPE_SPLICEOSOMAL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_U2_TYPE_SPLICEOSOMAL_COMPLEX","description":"Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends."} {"geneset":"GO_PLASMA_MEMBRANE_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLASMA_MEMBRANE_RECEPTOR_COMPLEX","description":"Any protein complex that is part of the plasma membrane and which functions as a receptor."} {"geneset":"GO_ACROSOMAL_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACROSOMAL_MEMBRANE","description":"The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization."} {"geneset":"GO_MICROBODY_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROBODY_MEMBRANE","description":"The lipid bilayer surrounding a microbody."} {"geneset":"GO_BASAL_LAMINA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASAL_LAMINA","description":"A thin sheet of proteoglycans and glycoproteins, especially laminin, secreted by cells as an extracellular matrix."} {"geneset":"GO_COPI_VESICLE_COAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COPI_VESICLE_COAT","description":"One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state."} {"geneset":"GO_CYTOPLASMIC_SIDE_OF_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_SIDE_OF_MEMBRANE","description":"The side of a membrane that faces the cytoplasm."} {"geneset":"GO_PLATELET_ALPHA_GRANULE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_ALPHA_GRANULE_MEMBRANE","description":"The lipid bilayer surrounding the platelet alpha granule."} {"geneset":"GO_NEURON_PROJECTION_TERMINUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_TERMINUS","description":"The specialized, terminal region of a neuron projection such as an axon or a dendrite."} {"geneset":"GO_CYTOPLASMIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_REGION","description":"Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm\\"} {"geneset":"GO_PROTEASOME_REGULATORY_PARTICLE_BASE_SUBCOMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEASOME_REGULATORY_PARTICLE_BASE_SUBCOMPLEX","description":"The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex."} {"geneset":"GO_SECRETORY_GRANULE_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECRETORY_GRANULE_LUMEN","description":"The volume enclosed by the membrane of a secretory granule."} {"geneset":"GO_RIBOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOME","description":"An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins."} {"geneset":"GO_MHC_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MHC_PROTEIN_COMPLEX","description":"A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen."} {"geneset":"GO_ACTIN_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_CYTOSKELETON","description":"The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes."} {"geneset":"GO_GLYCOPROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOPROTEIN_COMPLEX","description":"A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds."} {"geneset":"GO_COATED_PIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COATED_PIT","description":"A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes."} {"geneset":"GO_EXOCYTIC_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXOCYTIC_VESICLE","description":"A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis."} {"geneset":"GO_RNA_POLYMERASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_COMPLEX","description":"Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits."} {"geneset":"GO_MRNA_CLEAVAGE_FACTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_CLEAVAGE_FACTOR_COMPLEX","description":"Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules."} {"geneset":"GO_PERINUCLEAR_REGION_OF_CYTOPLASM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERINUCLEAR_REGION_OF_CYTOPLASM","description":"Cytoplasm situated near, or occurring around, the nucleus."} {"geneset":"GO_NUCLEOLAR_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOLAR_PART","description":"Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis."} {"geneset":"GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_COMPLEX","description":"A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase II."} {"geneset":"GO_INO80_TYPE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INO80_TYPE_COMPLEX","description":"A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair."} {"geneset":"GO_CELL_CORTEX_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CORTEX_PART","description":"Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins."} {"geneset":"GO_SMN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMN_COMPLEX","description":"A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus."} {"geneset":"GO_GOLGI_STACK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_STACK","description":"The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack."} {"geneset":"GO_SCF_UBIQUITIN_LIGASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SCF_UBIQUITIN_LIGASE_COMPLEX","description":"A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)."} {"geneset":"GO_CD40_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CD40_RECEPTOR_COMPLEX","description":"A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules."} {"geneset":"GO_BLOC_1_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLOC_1_COMPLEX","description":"A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins."} {"geneset":"GO_T_CELL_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_CELL_RECEPTOR_COMPLEX","description":"A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains."} {"geneset":"GO_CYTOSOLIC_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSOLIC_PART","description":"Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components."} {"geneset":"GO_VACUOLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLE","description":"A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol."} {"geneset":"GO_SECRETORY_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECRETORY_VESICLE","description":"A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space."} {"geneset":"GO_NUCLEAR_SPECK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_SPECK","description":"A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy."} {"geneset":"GO_NUCLEAR_TRANSCRIPTIONAL_REPRESSOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_TRANSCRIPTIONAL_REPRESSOR_COMPLEX","description":"A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription."} {"geneset":"GO_NUCLEAR_CYCLIN_DEPENDENT_PROTEIN_KINASE_HOLOENZYME_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_CYCLIN_DEPENDENT_PROTEIN_KINASE_HOLOENZYME_COMPLEX","description":"Cyclin-dependent protein kinase (CDK) complex found in the nucleus."} {"geneset":"GO_SITE_OF_POLARIZED_GROWTH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SITE_OF_POLARIZED_GROWTH","description":"Any part of a cell where non-isotropic growth takes place."} {"geneset":"GO_ENDOCYTIC_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCYTIC_VESICLE","description":"A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting."} {"geneset":"GO_CHROMOSOMAL_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOMAL_REGION","description":"Any subdivision of a chromosome along its length."} {"geneset":"GO_INCLUSION_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INCLUSION_BODY","description":"A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers."} {"geneset":"GO_MITOTIC_SPINDLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOTIC_SPINDLE","description":"A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules."} {"geneset":"GO_ANAPHASE_PROMOTING_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANAPHASE_PROMOTING_COMPLEX","description":"A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B."} {"geneset":"GO_NUCLEAR_INCLUSION_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_INCLUSION_BODY","description":"An intranuclear focus at which aggregated proteins have been sequestered."} {"geneset":"GO_CELL_PROJECTION_CYTOPLASM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PROJECTION_CYTOPLASM","description":"All of the contents of a cell projection, excluding the plasma membrane surrounding the projection."} {"geneset":"GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX_PROTON_TRANSPORTING_DOMAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX_PROTON_TRANSPORTING_DOMAIN","description":"A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins."} {"geneset":"GO_MALE_GERM_CELL_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MALE_GERM_CELL_NUCLEUS","description":"The nucleus of a male germ cell, a reproductive cell in males."} {"geneset":"GO_MYOFILAMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOFILAMENT","description":"Any of the smallest contractile units of a myofibril (striated muscle fiber)."} {"geneset":"GO_GEMINI_OF_COILED_BODIES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GEMINI_OF_COILED_BODIES","description":"Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA)."} {"geneset":"GO_CELL_PROJECTION_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PROJECTION_MEMBRANE","description":"The portion of the plasma membrane surrounding a cell surface projection."} {"geneset":"GO_APICAL_PART_OF_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APICAL_PART_OF_CELL","description":"The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_ENDOPLASMIC_RETICULUM_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_ENDOPLASMIC_RETICULUM_MEMBRANE","description":"The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane."} {"geneset":"GO_SPINDLE_POLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINDLE_POLE","description":"Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules."} {"geneset":"GO_FANCONI_ANAEMIA_NUCLEAR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FANCONI_ANAEMIA_NUCLEAR_COMPLEX","description":"A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage."} {"geneset":"GO_SEX_CHROMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEX_CHROMOSOME","description":"A chromosome involved in sex determination."} {"geneset":"GO_MRNA_CLEAVAGE_AND_POLYADENYLATION_SPECIFICITY_FACTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_CLEAVAGE_AND_POLYADENYLATION_SPECIFICITY_FACTOR_COMPLEX","description":"A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal."} {"geneset":"GO_NEURON_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PART","description":"Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system."} {"geneset":"GO_CAJAL_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CAJAL_BODY","description":"A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA."} {"geneset":"GO_ROUGH_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ROUGH_ENDOPLASMIC_RETICULUM","description":"The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae."} {"geneset":"GO_TRANSFERASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_COMPLEX","description":"A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)."} {"geneset":"GO_VACUOLAR_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLAR_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX","description":"A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen."} {"geneset":"GO_APICAL_JUNCTION_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APICAL_JUNCTION_COMPLEX","description":"A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability."} {"geneset":"GO_MICROBODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROBODY","description":"Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)."} {"geneset":"GO_GERM_CELL_NUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GERM_CELL_NUCLEUS","description":"The nucleus of a germ cell, a reproductive cell in multicellular organisms."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE","description":"The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane."} {"geneset":"GO_PORE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PORE_COMPLEX","description":"Any small opening in a membrane that allows the passage of gases and/or liquids."} {"geneset":"GO_LUMENAL_SIDE_OF_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LUMENAL_SIDE_OF_MEMBRANE","description":"Any side (leaflet) of a membrane that faces the lumen of an organelle."} {"geneset":"GO_GOLGI_ASSOCIATED_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_ASSOCIATED_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a vesicle associated with the Golgi apparatus."} {"geneset":"GO_CYTOPLASMIC_EXOSOME_RNASE_COMPLEX_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_EXOSOME_RNASE_COMPLEX_","description":"Complex of 3'-5' exoribonucleases found in the cytoplasm."} {"geneset":"GO_LIPID_PARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_PARTICLE","description":"An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_PEROXISOMAL_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_PEROXISOMAL_MEMBRANE","description":"The component of the peroxisomal membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane."} {"geneset":"GO_VESICLE_COAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_COAT","description":"A membrane coat found on a coated vesicle."} {"geneset":"GO_POSTSYNAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSTSYNAPSE","description":"The part of a synapse that is part of the post-synaptic cell."} {"geneset":"GO_PRECATALYTIC_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRECATALYTIC_SPLICEOSOME","description":"A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs."} {"geneset":"GO_AXON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXON","description":"The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter."} {"geneset":"GO_CLATHRIN_COAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COAT","description":"A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes."} {"geneset":"GO_BASAL_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASAL_PLASMA_MEMBRANE","description":"The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis."} {"geneset":"GO_MCM_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MCM_COMPLEX","description":"A hexameric protein complex required for the initiation and regulation of DNA replication."} {"geneset":"GO_NUCLEAR_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_BODY","description":"Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins."} {"geneset":"GO_AMPA_GLUTAMATE_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMPA_GLUTAMATE_RECEPTOR_COMPLEX","description":"An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus."} {"geneset":"GO_CLATHRIN_COATED_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COATED_VESICLE","description":"A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes."} {"geneset":"GO_PROTEIN_KINASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_COMPLEX","description":"A protein complex which is capable of protein kinase activity."} {"geneset":"GO_VESICLE_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VESICLE_LUMEN","description":"The volume enclosed by the membrane or protein that forms a vesicle."} {"geneset":"GO_PROTEIN_COMPLEX_INVOLVED_IN_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_COMPLEX_INVOLVED_IN_CELL_ADHESION","description":"Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion."} {"geneset":"GO_TRANS_GOLGI_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANS_GOLGI_NETWORK","description":"The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination."} {"geneset":"GO_PHOTORECEPTOR_OUTER_SEGMENT_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_OUTER_SEGMENT_MEMBRANE","description":"The membrane surrounding the outer segment of a vertebrate photoreceptor."} {"geneset":"GO_HOPS_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOPS_COMPLEX","description":"A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion."} {"geneset":"GO_IONOTROPIC_GLUTAMATE_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IONOTROPIC_GLUTAMATE_RECEPTOR_COMPLEX","description":"A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex."} {"geneset":"GO_ORGANELLE_MEMBRANE_CONTACT_SITE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_MEMBRANE_CONTACT_SITE","description":"A zone of apposition between the membranes of two organelles, structured by bridging complexes. Membrane contact sites (MCSs) are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions."} {"geneset":"GO_SODIUM_CHANNEL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_CHANNEL_COMPLEX","description":"An ion channel complex through which sodium ions pass."} {"geneset":"GO_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX","description":"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs."} {"geneset":"GO_CCR4_NOT_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CCR4_NOT_COMPLEX","description":"The evolutionarily conserved CCR4-NOT complex is involved in several aspects of mRNA metabolism, including repression and activation of mRNA initiation, control of mRNA elongation, and the deadenylation and subsequent degradation of mRNA. In Saccharomyces the CCR4-NOT complex comprises a core complex of 9 proteins (Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p), Caf4p, Caf16p, and several less well characterized proteins."} {"geneset":"GO_M_BAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_M_BAND","description":"The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines."} {"geneset":"GO_NPBAF_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NPBAF_COMPLEX","description":"A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells."} {"geneset":"GO_OUTER_MITOCHONDRIAL_MEMBRANE_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OUTER_MITOCHONDRIAL_MEMBRANE_PROTEIN_COMPLEX","description":"Any protein complex that is part of the outer mitochondrial membrane."} {"geneset":"GO_CORTICAL_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORTICAL_CYTOSKELETON","description":"The portion of the cytoskeleton that lies just beneath the plasma membrane."} {"geneset":"GO_MYOSIN_FILAMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOSIN_FILAMENT","description":"A protein complex containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament."} {"geneset":"GO_NEURONAL_POSTSYNAPTIC_DENSITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURONAL_POSTSYNAPTIC_DENSITY","description":"A postsynaptic density that is part of a neuron."} {"geneset":"GO_INTERMEDIATE_FILAMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERMEDIATE_FILAMENT","description":"A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins."} {"geneset":"GO_CYTOSOLIC_SMALL_RIBOSOMAL_SUBUNIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSOLIC_SMALL_RIBOSOMAL_SUBUNIT","description":"The small subunit of a ribosome located in the cytosol."} {"geneset":"GO_SNARE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SNARE_COMPLEX","description":"A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25."} {"geneset":"GO_DNA_REPLICATION_FACTOR_A_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_REPLICATION_FACTOR_A_COMPLEX","description":"A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa."} {"geneset":"GO_UBIQUITIN_LIGASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_LIGASE_COMPLEX","description":"A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex."} {"geneset":"GO_ROUGH_ENDOPLASMIC_RETICULUM_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ROUGH_ENDOPLASMIC_RETICULUM_MEMBRANE","description":"The lipid bilayer surrounding the rough endoplasmic reticulum."} {"geneset":"GO_AXON_INITIAL_SEGMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXON_INITIAL_SEGMENT","description":"Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment."} {"geneset":"GO_U2_SNRNP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_U2_SNRNP","description":"A ribonucleoprotein complex that contains small nuclear RNA U2."} {"geneset":"GO_ACTIN_FILAMENT_BUNDLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT_BUNDLE","description":"An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness."} {"geneset":"GO_PERINUCLEAR_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERINUCLEAR_ENDOPLASMIC_RETICULUM","description":"The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes."} {"geneset":"GO_CILIARY_TIP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIARY_TIP","description":"Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction."} {"geneset":"GO_PRONUCLEUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRONUCLEUS","description":"The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents."} {"geneset":"GO_ORGANELLE_INNER_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_INNER_MEMBRANE","description":"The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites."} {"geneset":"GO_GOLGI_CISTERNA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_CISTERNA","description":"Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex."} {"geneset":"GO_NUCLEAR_NUCLEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_NUCLEOSOME","description":"A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the nucleus into higher order structures."} {"geneset":"GO_PCG_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PCG_PROTEIN_COMPLEX","description":"A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure."} {"geneset":"GO_GOLGI_APPARATUS_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_APPARATUS_PART","description":"Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack."} {"geneset":"GO_POTASSIUM_CHANNEL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POTASSIUM_CHANNEL_COMPLEX","description":"An ion channel complex through which potassium ions pass."} {"geneset":"GO_SMALL_RIBOSOMAL_SUBUNIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMALL_RIBOSOMAL_SUBUNIT","description":"The smaller of the two subunits of a ribosome."} {"geneset":"GO_COPI_COATED_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COPI_COATED_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a COPI-coated vesicle."} {"geneset":"GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX","description":"A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible."} {"geneset":"GO_CENTROSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTROSOME","description":"A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle."} {"geneset":"GO_SET1C_COMPASS_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SET1C_COMPASS_COMPLEX","description":"A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30."} {"geneset":"GO_CYTOPLASMIC_MRNA_PROCESSING_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_MRNA_PROCESSING_BODY","description":"A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci."} {"geneset":"GO_PROTEIN_PHOSPHATASE_TYPE_1_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_PHOSPHATASE_TYPE_1_COMPLEX","description":"A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity."} {"geneset":"GO_NODE_OF_RANVIER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NODE_OF_RANVIER","description":"An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed."} {"geneset":"GO_COMPACT_MYELIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COMPACT_MYELIN","description":"The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs."} {"geneset":"GO_MOTILE_CILIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MOTILE_CILIUM","description":"A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles."} {"geneset":"GO_MICROVILLUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROVILLUS","description":"Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells."} {"geneset":"GO_DENDRITIC_SHAFT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITIC_SHAFT","description":"Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines."} {"geneset":"GO_CYTOSOLIC_PROTEASOME_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSOLIC_PROTEASOME_COMPLEX","description":"A proteasome complex found in the cytosol of a cell."} {"geneset":"GO_PML_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PML_BODY","description":"A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection."} {"geneset":"GO_CELL_CORTEX_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CORTEX_REGION","description":"The complete extent of cell cortex that underlies some some region of the plasma membrane"} {"geneset":"GO_NEURON_SPINE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_SPINE","description":"A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_PART","description":"Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae."} {"geneset":"GO_NUCLEAR_CHROMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_CHROMOSOME","description":"A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact."} {"geneset":"GO_ENDOCYTIC_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCYTIC_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding an endocytic vesicle."} {"geneset":"GO_HIGH_DENSITY_LIPOPROTEIN_PARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HIGH_DENSITY_LIPOPROTEIN_PARTICLE","description":"A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process."} {"geneset":"GO_NMDA_SELECTIVE_GLUTAMATE_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NMDA_SELECTIVE_GLUTAMATE_RECEPTOR_COMPLEX","description":"An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD."} {"geneset":"GO_BLOOD_MICROPARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLOOD_MICROPARTICLE","description":"A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids."} {"geneset":"GO_PRERIBOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRERIBOSOME","description":"Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis."} {"geneset":"GO_PARANODE_REGION_OF_AXON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PARANODE_REGION_OF_AXON","description":"An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath."} {"geneset":"GO_AXONAL_GROWTH_CONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXONAL_GROWTH_CONE","description":"The migrating motile tip of a growing nerve cell axon."} {"geneset":"GO_PROTEIN_DNA_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DNA_COMPLEX","description":"A macromolecular complex containing both protein and DNA molecules."} {"geneset":"GO_APICAL_DENDRITE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APICAL_DENDRITE","description":"A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon."} {"geneset":"GO_ACTOMYOSIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTOMYOSIN","description":"Any complex of actin, myosin, and accessory proteins."} {"geneset":"GO_STEREOCILIUM_BUNDLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEREOCILIUM_BUNDLE","description":"A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes."} {"geneset":"GO_ORGANELLAR_RIBOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLAR_RIBOSOME","description":"A ribosome contained within a subcellular membrane-bounded organelle."} {"geneset":"GO_TRANSCRIPTIONAL_REPRESSOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONAL_REPRESSOR_COMPLEX","description":"A protein complex that possesses activity that prevents or downregulates transcription."} {"geneset":"GO_NUCLEAR_REPLICATION_FORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_REPLICATION_FORK","description":"The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes."} {"geneset":"GO_INVADOPODIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INVADOPODIUM","description":"A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate."} {"geneset":"GO_EXON_EXON_JUNCTION_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXON_EXON_JUNCTION_COMPLEX","description":"A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay."} {"geneset":"GO_CILIARY_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIARY_PART","description":"Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."} {"geneset":"GO_COSTAMERE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COSTAMERE","description":"Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix."} {"geneset":"GO_SWI_SNF_SUPERFAMILY_TYPE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SWI_SNF_SUPERFAMILY_TYPE_COMPLEX","description":"A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the core components and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP."} {"geneset":"GO_CHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN","description":"The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome."} {"geneset":"GO_BASEMENT_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASEMENT_MEMBRANE","description":"A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers."} {"geneset":"GO_BRUSH_BORDER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRUSH_BORDER","description":"The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell."} {"geneset":"GO_MITOCHONDRIAL_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_MATRIX","description":"The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation."} {"geneset":"GO_PLATELET_DENSE_TUBULAR_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_DENSE_TUBULAR_NETWORK","description":"A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin."} {"geneset":"GO_CELL_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_JUNCTION","description":"A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix."} {"geneset":"GO_NUCLEAR_CHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_CHROMATIN","description":"The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus."} {"geneset":"GO_COMPLEX_OF_COLLAGEN_TRIMERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COMPLEX_OF_COLLAGEN_TRIMERS","description":"A complex of collagen trimers such as a fibril or collagen network."} {"geneset":"GO_EARLY_ENDOSOME_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EARLY_ENDOSOME_MEMBRANE","description":"The lipid bilayer surrounding an early endosome."} {"geneset":"GO_TRANSCRIPTION_FACTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_COMPLEX","description":"A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription."} {"geneset":"GO_MYELIN_SHEATH","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYELIN_SHEATH","description":"An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system."} {"geneset":"GO_SPLICEOSOMAL_TRI_SNRNP_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPLICEOSOMAL_TRI_SNRNP_COMPLEX","description":"A spliceosomal snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins."} {"geneset":"GO_PLATELET_ALPHA_GRANULE_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_ALPHA_GRANULE_LUMEN","description":"The volume enclosed by the membrane of the platelet alpha granule."} {"geneset":"GO_MICROVILLUS_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROVILLUS_MEMBRANE","description":"The portion of the plasma membrane surrounding a microvillus."} {"geneset":"GO_RIBONUCLEOPROTEIN_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOPROTEIN_GRANULE","description":"A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions."} {"geneset":"GO_CLATHRIN_COATED_ENDOCYTIC_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COATED_ENDOCYTIC_VESICLE","description":"A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance."} {"geneset":"GO_ARP2_3_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARP2_3_PROTEIN_COMPLEX","description":"A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments."} {"geneset":"GO_LEADING_EDGE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEADING_EDGE_MEMBRANE","description":"The portion of the plasma membrane surrounding the leading edge of a motile cell."} {"geneset":"GO_CONTRACTILE_FIBER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONTRACTILE_FIBER","description":"Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle."} {"geneset":"GO_TRANSCRIPTION_FACTOR_TFTC_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_TFTC_COMPLEX","description":"A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity."} {"geneset":"GO_CYTOSOLIC_LARGE_RIBOSOMAL_SUBUNIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSOLIC_LARGE_RIBOSOMAL_SUBUNIT","description":"The large subunit of a ribosome located in the cytosol."} {"geneset":"GO_CLUSTER_OF_ACTIN_BASED_CELL_PROJECTIONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLUSTER_OF_ACTIN_BASED_CELL_PROJECTIONS","description":"A cell part consisting of multiple, closely packed actin-based cell projections."} {"geneset":"GO_PROTEINACEOUS_EXTRACELLULAR_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEINACEOUS_EXTRACELLULAR_MATRIX","description":"A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus."} {"geneset":"GO_PHAGOCYTIC_CUP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOCYTIC_CUP","description":"An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome."} {"geneset":"GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX_CATALYTIC_DOMAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX_CATALYTIC_DOMAIN","description":"A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled."} {"geneset":"GO_CYTOSKELETAL_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSKELETAL_PART","description":"Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice."} {"geneset":"GO_MICROTUBULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE","description":"Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle."} {"geneset":"GO_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSKELETON","description":"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles."} {"geneset":"GO_COPI_COATED_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COPI_COATED_VESICLE","description":"A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport."} {"geneset":"GO_NUCLEAR_EUCHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_EUCHROMATIN","description":"The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin."} {"geneset":"GO_CORTICAL_ACTIN_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORTICAL_ACTIN_CYTOSKELETON","description":"The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane."} {"geneset":"GO_PERICENTRIC_HETEROCHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERICENTRIC_HETEROCHROMATIN","description":"Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3."} {"geneset":"GO_GLIAL_CELL_PROJECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLIAL_CELL_PROJECTION","description":"A prolongation or process extending from a glial cell."} {"geneset":"GO_SPECIFIC_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPECIFIC_GRANULE","description":"Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase."} {"geneset":"GO_HETEROTRIMERIC_G_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HETEROTRIMERIC_G_PROTEIN_COMPLEX","description":"Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_LUMEN","description":"The volume enclosed by the membranes of the endoplasmic reticulum."} {"geneset":"GO_LATERAL_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LATERAL_PLASMA_MEMBRANE","description":"The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells."} {"geneset":"GO_BANDED_COLLAGEN_FIBRIL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BANDED_COLLAGEN_FIBRIL","description":"A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)."} {"geneset":"GO_EXTRINSIC_COMPONENT_OF_ORGANELLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRINSIC_COMPONENT_OF_ORGANELLE_MEMBRANE","description":"The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region."} {"geneset":"GO_PLATELET_DENSE_GRANULE_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_DENSE_GRANULE_LUMEN","description":"The volume enclosed by the membrane of the platelet dense granule."} {"geneset":"GO_INTRACELLULAR_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_VESICLE","description":"Any vesicle that is part of the intracellular region."} {"geneset":"GO_MYOSIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOSIN_COMPLEX","description":"A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes."} {"geneset":"GO_VOLTAGE_GATED_SODIUM_CHANNEL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_SODIUM_CHANNEL_COMPLEX","description":"A sodium channel in a cell membrane whose opening is governed by the membrane potential."} {"geneset":"GO_DNA_REPAIR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_REPAIR_COMPLEX","description":"A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway."} {"geneset":"GO_CLATHRIN_VESICLE_COAT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_VESICLE_COAT","description":"A clathrin coat found on a vesicle."} {"geneset":"GO_SIN3_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIN3_COMPLEX","description":"A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins."} {"geneset":"GO_ESCRT_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESCRT_COMPLEX","description":"An endosomal sorting complex required for transport."} {"geneset":"GO_CELL_SUBSTRATE_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_SUBSTRATE_JUNCTION","description":"A cell junction that forms a connection between a cell and the extracellular matrix."} {"geneset":"GO_CILIARY_TRANSITION_ZONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIARY_TRANSITION_ZONE","description":"A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition."} {"geneset":"GO_U5_SNRNP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_U5_SNRNP","description":"A ribonucleoprotein complex that contains small nuclear RNA U5."} {"geneset":"GO_ENDOCYTIC_VESICLE_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOCYTIC_VESICLE_LUMEN","description":"The volume enclosed by the membrane of an endocytic vesicle."} {"geneset":"GO_HISTONE_METHYLTRANSFERASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_METHYLTRANSFERASE_COMPLEX","description":"A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins."} {"geneset":"GO_MICROTUBULE_PLUS_END","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_PLUS_END","description":"The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability."} {"geneset":"GO_SAGA_TYPE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SAGA_TYPE_COMPLEX","description":"A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins."} {"geneset":"GO_CELL_DIVISION_SITE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_DIVISION_SITE","description":"The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles."} {"geneset":"GO_EXTRACELLULAR_MATRIX_COMPONENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_MATRIX_COMPONENT","description":"Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants)."} {"geneset":"GO_NUCLEAR_HETEROCHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_HETEROCHROMATIN","description":"A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin."} {"geneset":"GO_TCTN_B9D_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TCTN_B9D_COMPLEX","description":"A protein complex that is located at the ciliary transition zone and consists of tectonic proteins, B9 domain-containing proteins and other proteins. Acts as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. In mouse, members of the complex include TCTN1, TCTN2, B9D1, MKS1, CC2D2A and other proteins."} {"geneset":"GO_PRC1_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRC1_COMPLEX","description":"A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling."} {"geneset":"GO_GOLGI_ASSOCIATED_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_ASSOCIATED_VESICLE","description":"Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_GOLGI_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_GOLGI_MEMBRANE","description":"The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane."} {"geneset":"GO_SYNAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPSE","description":"The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane."} {"geneset":"GO_CHLORIDE_CHANNEL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHLORIDE_CHANNEL_COMPLEX","description":"An ion channel complex through which chloride ions pass."} {"geneset":"GO_CLATHRIN_COAT_OF_COATED_PIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COAT_OF_COATED_PIT","description":"The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex."} {"geneset":"GO_SIN3_TYPE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIN3_TYPE_COMPLEX","description":"Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex."} {"geneset":"GO_POSTSYNAPTIC_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POSTSYNAPTIC_MEMBRANE","description":"A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane."} {"geneset":"GO_SMALL_SUBUNIT_PROCESSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMALL_SUBUNIT_PROCESSOME","description":"A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins."} {"geneset":"GO_RUFFLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RUFFLE_MEMBRANE","description":"The portion of the plasma membrane surrounding a ruffle."} {"geneset":"GO_EXTERNAL_ENCAPSULATING_STRUCTURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTERNAL_ENCAPSULATING_STRUCTURE","description":"A structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space."} {"geneset":"GO_CELL_TRAILING_EDGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_TRAILING_EDGE","description":"The area of a motile cell opposite to the direction of movement."} {"geneset":"GO_CATION_CHANNEL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_CHANNEL_COMPLEX","description":"An ion channel complex through which cations pass."} {"geneset":"GO_MLL1_2_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MLL1_2_COMPLEX","description":"A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species."} {"geneset":"GO_METHYLTRANSFERASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METHYLTRANSFERASE_COMPLEX","description":"A protein complex that possesses methyltransferase activity."} {"geneset":"GO_NUCLEOPLASM_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOPLASM_PART","description":"Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus."} {"geneset":"GO_SYNAPTONEMAL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTONEMAL_COMPLEX","description":"A proteinaceous scaffold found between homologous chromosomes during meiosis."} {"geneset":"GO_ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT","description":"The smaller of the two subunits of an organellar ribosome."} {"geneset":"GO_CELL_CELL_ADHERENS_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_ADHERENS_JUNCTION","description":"An adherens junction which connects a cell to another cell."} {"geneset":"GO_N_TERMINAL_PROTEIN_ACETYLTRANSFERASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_N_TERMINAL_PROTEIN_ACETYLTRANSFERASE_COMPLEX","description":"A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule."} {"geneset":"GO_PROTON_TRANSPORTING_ATP_SYNTHASE_COMPLEX_COUPLING_FACTOR_F_O_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTON_TRANSPORTING_ATP_SYNTHASE_COMPLEX_COUPLING_FACTOR_F_O_","description":"All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins."} {"geneset":"GO_CONNEXON_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONNEXON_COMPLEX","description":"An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction."} {"geneset":"GO_GOLGI_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_MEMBRANE","description":"The lipid bilayer surrounding any of the compartments of the Golgi apparatus."} {"geneset":"GO_COATED_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COATED_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a coated vesicle."} {"geneset":"GO_SMOOTH_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMOOTH_ENDOPLASMIC_RETICULUM","description":"The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER."} {"geneset":"GO_ENDORIBONUCLEASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDORIBONUCLEASE_COMPLEX","description":"A protein complex which is capable of endoribonuclease activity."} {"geneset":"GO_ATPASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_COMPLEX","description":"A protein complex which is capable of ATPase activity."} {"geneset":"GO_NUCLEAR_INNER_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_INNER_MEMBRANE","description":"The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope."} {"geneset":"GO_LATE_ENDOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LATE_ENDOSOME","description":"A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center."} {"geneset":"GO_VACUOLAR_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLAR_LUMEN","description":"The volume enclosed within the vacuolar membrane."} {"geneset":"GO_LAMELLIPODIUM_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAMELLIPODIUM_MEMBRANE","description":"The portion of the plasma membrane surrounding a lamellipodium."} {"geneset":"GO_EXOSOME_RNASE_COMPLEX_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXOSOME_RNASE_COMPLEX_","description":"Complex of 3'-5' exoribonucleases."} {"geneset":"GO_ER_TO_GOLGI_TRANSPORT_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ER_TO_GOLGI_TRANSPORT_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi."} {"geneset":"GO_SPINDLE_MIDZONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINDLE_MIDZONE","description":"The area in the center of the spindle where the spindle microtubules from opposite poles overlap."} {"geneset":"GO_PRESYNAPTIC_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRESYNAPTIC_MEMBRANE","description":"A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane."} {"geneset":"GO_NUCLEAR_MEMBRANE_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_MEMBRANE_PART","description":"Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells."} {"geneset":"GO_XY_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_XY_BODY","description":"A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery."} {"geneset":"GO_MITOCHONDRIAL_MEMBRANE_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_MEMBRANE_PART","description":"Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope."} {"geneset":"GO_COP9_SIGNALOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COP9_SIGNALOSOME","description":"A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome."} {"geneset":"GO_INNER_MITOCHONDRIAL_MEMBRANE_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INNER_MITOCHONDRIAL_MEMBRANE_PROTEIN_COMPLEX","description":"Any protein complex that is part of the inner mitochondrial membrane."} {"geneset":"GO_NEURON_PROJECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION","description":"A prolongation or process extending from a nerve cell, e.g. an axon or dendrite."} {"geneset":"GO_BLOC_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BLOC_COMPLEX","description":"Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex."} {"geneset":"GO_BETA_CATENIN_DESTRUCTION_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_CATENIN_DESTRUCTION_COMPLEX","description":"A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome."} {"geneset":"GO_APICOLATERAL_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APICOLATERAL_PLASMA_MEMBRANE","description":"The apical end of the lateral plasma membrane of epithelial cells."} {"geneset":"GO_CATALYTIC_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATALYTIC_COMPLEX","description":"A protein complex which is capable of catalytic activity."} {"geneset":"GO_FILOPODIUM_TIP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FILOPODIUM_TIP","description":"The end of a filopodium distal to the body of the cell."} {"geneset":"GO_MISMATCH_REPAIR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MISMATCH_REPAIR_COMPLEX","description":"Any complex formed of proteins that act in mismatch repair."} {"geneset":"GO_AXONEME_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXONEME_PART","description":"Any constituent part of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements."} {"geneset":"GO_KINETOCHORE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINETOCHORE","description":"A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules."} {"geneset":"GO_INTERSTITIAL_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERSTITIAL_MATRIX","description":"A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens."} {"geneset":"GO_EXTRACELLULAR_SPACE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_SPACE","description":"That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid."} {"geneset":"GO_CYTOPLASMIC_DYNEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_DYNEIN_COMPLEX","description":"Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains."} {"geneset":"GO_ENDOLYSOSOME_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOLYSOSOME_MEMBRANE","description":"The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome."} {"geneset":"GO_PRESPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRESPLICEOSOME","description":"A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex."} {"geneset":"GO_CHD_TYPE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHD_TYPE_COMPLEX","description":"A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure."} {"geneset":"GO_SPERM_PRINCIPAL_PIECE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERM_PRINCIPAL_PIECE","description":"The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece."} {"geneset":"GO_CATALYTIC_STEP_2_SPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATALYTIC_STEP_2_SPLICEOSOME","description":"A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs."} {"geneset":"GO_VIRION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VIRION","description":"The complete fully infectious extracellular virus particle."} {"geneset":"GO_VACUOLAR_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLAR_PART","description":"Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material."} {"geneset":"GO_MITOCHONDRIAL_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_PART","description":"Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration."} {"geneset":"GO_MITOCHONDRION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRION","description":"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration."} {"geneset":"GO_CELL_SURFACE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_SURFACE","description":"The external part of the cell wall and/or plasma membrane."} {"geneset":"GO_HEMOGLOBIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEMOGLOBIN_COMPLEX","description":"An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group."} {"geneset":"GO_DENDRITE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITE_MEMBRANE","description":"The portion of the plasma membrane surrounding a dendrite."} {"geneset":"GO_RESPIRATORY_CHAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RESPIRATORY_CHAIN","description":"The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient."} {"geneset":"GO_U4_U6_X_U5_TRI_SNRNP_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_U4_U6_X_U5_TRI_SNRNP_COMPLEX","description":"A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins."} {"geneset":"GO_PRP19_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRP19_COMPLEX","description":"A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p."} {"geneset":"GO_CONDENSED_CHROMOSOME_CENTROMERIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONDENSED_CHROMOSOME_CENTROMERIC_REGION","description":"The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome."} {"geneset":"GO_TRICARBOXYLIC_ACID_CYCLE_ENZYME_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRICARBOXYLIC_ACID_CYCLE_ENZYME_COMPLEX","description":"Any of the heteromeric enzymes that act in the TCA cycle."} {"geneset":"GO_STAGA_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STAGA_COMPLEX","description":"A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The composition is similar to that of the SAGA complex; for example, the human complex contains the transcription-transformation cofactor TRRAP, hGCN5L acetylase, novel human ADA-like and SPT-like cofactors, and a subset of TAFs."} {"geneset":"GO_SPERM_MIDPIECE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERM_MIDPIECE","description":"The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece."} {"geneset":"GO_SECRETORY_GRANULE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECRETORY_GRANULE_MEMBRANE","description":"The lipid bilayer surrounding a secretory granule."} {"geneset":"GO_DNA_PACKAGING_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_PACKAGING_COMPLEX","description":"A protein complex that plays a role in the process of DNA packaging."} {"geneset":"GO_POLE_PLASM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLE_PLASM","description":"Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo."} {"geneset":"GO_MEMBRANE_MICRODOMAIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_MICRODOMAIN","description":"A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it."} {"geneset":"GO_TRANSPORTER_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSPORTER_COMPLEX","description":"A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells."} {"geneset":"GO_SIDE_OF_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIDE_OF_MEMBRANE","description":"A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface."} {"geneset":"GO_PHOTORECEPTOR_CONNECTING_CILIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_CONNECTING_CILIUM","description":"A nonmotile primary cilium that has a 9+0 microtubule array and forms the portion of the axoneme traversing the boundary between the photoreceptor inner and outer segments."} {"geneset":"GO_CONDENSED_CHROMOSOME_OUTER_KINETOCHORE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONDENSED_CHROMOSOME_OUTER_KINETOCHORE","description":"The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions."} {"geneset":"GO_CLATHRIN_COATED_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COATED_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a clathrin-coated vesicle."} {"geneset":"GO_MEMBRANE_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_PROTEIN_COMPLEX","description":"Any protein complex that is part of a membrane."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_THE_CYTOPLASMIC_SIDE_OF_THE_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_THE_CYTOPLASMIC_SIDE_OF_THE_PLASMA_MEMBRANE","description":"The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only."} {"geneset":"GO_NUCLEAR_OUTER_MEMBRANE_ENDOPLASMIC_RETICULUM_MEMBRANE_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_OUTER_MEMBRANE_ENDOPLASMIC_RETICULUM_MEMBRANE_NETWORK","description":"The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane."} {"geneset":"GO_TRANSCRIPTIONALLY_ACTIVE_CHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONALLY_ACTIVE_CHROMATIN","description":"The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed."} {"geneset":"GO_U2_TYPE_PRESPLICEOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_U2_TYPE_PRESPLICEOSOME","description":"A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_CHAPERONE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_CHAPERONE_COMPLEX","description":"A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1."} {"geneset":"GO_SCHMIDT_LANTERMAN_INCISURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SCHMIDT_LANTERMAN_INCISURE","description":"Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier."} {"geneset":"GO_SEMAPHORIN_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEMAPHORIN_RECEPTOR_COMPLEX","description":"A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor."} {"geneset":"GO_AXON_CYTOPLASM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXON_CYTOPLASM","description":"Any cytoplasm that is part of a axon."} {"geneset":"GO_LAMELLIPODIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAMELLIPODIUM","description":"A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments."} {"geneset":"GO_NUCLEAR_TRANSCRIPTION_FACTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_TRANSCRIPTION_FACTOR_COMPLEX","description":"A protein complex, located in the nucleus, that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription."} {"geneset":"GO_MIDBODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MIDBODY","description":"A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis."} {"geneset":"GO_HETEROCHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HETEROCHROMATIN","description":"A compact and highly condensed form of chromatin."} {"geneset":"GO_DNA_HELICASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_HELICASE_COMPLEX","description":"A protein complex that possesses DNA helicase activity."} {"geneset":"GO_CHROMOCENTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOCENTER","description":"A region in which centric, heterochromatic portions of one or more chromosomes form a compact structure."} {"geneset":"GO_SPLICEOSOMAL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPLICEOSOMAL_COMPLEX","description":"Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA."} {"geneset":"GO_NADH_DEHYDROGENASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NADH_DEHYDROGENASE_COMPLEX","description":"An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone."} {"geneset":"GO_SARCOPLASM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SARCOPLASM","description":"The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum."} {"geneset":"GO_DNA_DIRECTED_RNA_POLYMERASE_II_CORE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DIRECTED_RNA_POLYMERASE_II_CORE_COMPLEX","description":"RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template."} {"geneset":"GO_CELL_CELL_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_JUNCTION","description":"A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals."} {"geneset":"GO_CONDENSED_NUCLEAR_CHROMOSOME_CENTROMERIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONDENSED_NUCLEAR_CHROMOSOME_CENTROMERIC_REGION","description":"The region of a condensed nuclear chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_KINASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_KINASE_COMPLEX","description":"A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too."} {"geneset":"GO_INTRACILIARY_TRANSPORT_PARTICLE_B","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACILIARY_TRANSPORT_PARTICLE_B","description":"The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa."} {"geneset":"GO_DNA_DIRECTED_RNA_POLYMERASE_I_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DIRECTED_RNA_POLYMERASE_I_COMPLEX","description":"RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template."} {"geneset":"GO_REPLICATION_FORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REPLICATION_FORK","description":"The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes."} {"geneset":"GO_IMMUNOGLOBULIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNOGLOBULIN_COMPLEX","description":"A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph."} {"geneset":"GO_SMALL_NUCLEOLAR_RIBONUCLEOPROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMALL_NUCLEOLAR_RIBONUCLEOPROTEIN_COMPLEX","description":"A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type."} {"geneset":"GO_SMN_SM_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMN_SM_PROTEIN_COMPLEX","description":"A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm."} {"geneset":"GO_RECEPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_COMPLEX","description":"Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."} {"geneset":"GO_INTRACILIARY_TRANSPORT_PARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACILIARY_TRANSPORT_PARTICLE","description":"A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules."} {"geneset":"GO_ANCHORING_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANCHORING_JUNCTION","description":"A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix."} {"geneset":"GO_PRERIBOSOME_LARGE_SUBUNIT_PRECURSOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRERIBOSOME_LARGE_SUBUNIT_PRECURSOR","description":"A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT_MEMBRANE","description":"The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system."} {"geneset":"GO_EXTRINSIC_COMPONENT_OF_CYTOPLASMIC_SIDE_OF_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRINSIC_COMPONENT_OF_CYTOPLASMIC_SIDE_OF_PLASMA_MEMBRANE","description":"The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region."} {"geneset":"GO_GAMMA_TUBULIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GAMMA_TUBULIN_COMPLEX","description":"A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species."} {"geneset":"GO_POLYSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYSOME","description":"A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro."} {"geneset":"GO_PRESYNAPTIC_ACTIVE_ZONE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRESYNAPTIC_ACTIVE_ZONE","description":"A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix."} {"geneset":"GO_EXOCYST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXOCYST","description":"A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals."} {"geneset":"GO_DNA_DIRECTED_RNA_POLYMERASE_III_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DIRECTED_RNA_POLYMERASE_III_COMPLEX","description":"RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template."} {"geneset":"GO_PODOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PODOSOME","description":"An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm."} {"geneset":"GO_CILIARY_BASE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIARY_BASE","description":"Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area."} {"geneset":"GO_AUTOPHAGOSOME_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AUTOPHAGOSOME_MEMBRANE","description":"The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_INNER_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_INNER_MEMBRANE","description":"The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane."} {"geneset":"GO_DYNEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DYNEIN_COMPLEX","description":"Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity."} {"geneset":"GO_ORGANELLAR_LARGE_RIBOSOMAL_SUBUNIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLAR_LARGE_RIBOSOMAL_SUBUNIT","description":"The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site)."} {"geneset":"GO_CARBOXY_TERMINAL_DOMAIN_PROTEIN_KINASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOXY_TERMINAL_DOMAIN_PROTEIN_KINASE_COMPLEX","description":"A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5."} {"geneset":"GO_DESMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DESMOSOME","description":"A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism."} {"geneset":"GO_RECYCLING_ENDOSOME_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECYCLING_ENDOSOME_MEMBRANE","description":"The lipid bilayer surrounding a recycling endosome."} {"geneset":"GO_ORGANELLE_ENVELOPE_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_ENVELOPE_LUMEN","description":"The region between the inner and outer lipid bilayers of an organelle envelope."} {"geneset":"GO_SPINDLE_MICROTUBULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINDLE_MICROTUBULE","description":"Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole."} {"geneset":"GO_GOLGI_TRANSPORT_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_TRANSPORT_COMPLEX","description":"A complex of proteins that, in vitro, stimulates intra-Golgi transport; a 13S complex, about 800 kDa in size and consists of at least five polypeptides. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p)."} {"geneset":"GO_OUTER_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OUTER_MEMBRANE","description":"The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites."} {"geneset":"GO_RIBOSOMAL_SUBUNIT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOMAL_SUBUNIT","description":"Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit."} {"geneset":"GO_CIS_GOLGI_NETWORK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CIS_GOLGI_NETWORK","description":"The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum."} {"geneset":"GO_TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE","description":"A vesicle that mediates transport between the trans-Golgi network and other parts of the cell."} {"geneset":"GO_INHIBITORY_SYNAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INHIBITORY_SYNAPSE","description":"A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell."} {"geneset":"GO_MICROTUBULE_END","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_END","description":"Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end."} {"geneset":"GO_SUPRAMOLECULAR_FIBER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUPRAMOLECULAR_FIBER","description":"A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure."} {"geneset":"GO_FIBRIL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FIBRIL","description":"Extracellular matrix material consisting of polysaccharides and protein."} {"geneset":"GO_NONMOTILE_PRIMARY_CILIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NONMOTILE_PRIMARY_CILIUM","description":"A primary cilium which contains a variable array of axonemal microtubules but does not contain molecular motors. Nonmotile primary cilia are found on many different cell types and function as sensory organelles that concentrate and organize sensory signaling molecules."} {"geneset":"GO_NUCLEAR_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_MATRIX","description":"The dense fibrillar network lying on the inner side of the nuclear membrane."} {"geneset":"GO_AXOLEMMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXOLEMMA","description":"The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness."} {"geneset":"GO_MICROTUBULE_ASSOCIATED_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_ASSOCIATED_COMPLEX","description":"Any multimeric complex connected to a microtubule."} {"geneset":"GO_APICAL_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APICAL_PLASMA_MEMBRANE","description":"The region of the plasma membrane located at the apical end of the cell."} {"geneset":"GO_PHAGOCYTIC_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHAGOCYTIC_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a phagocytic vesicle."} {"geneset":"GO_PHOTORECEPTOR_INNER_SEGMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_INNER_SEGMENT","description":"The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs."} {"geneset":"GO_EUCHROMATIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EUCHROMATIN","description":"A dispersed and relatively uncompacted form of chromatin."} {"geneset":"GO_CELL_CORTEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CORTEX","description":"The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins."} {"geneset":"GO_DNA_DIRECTED_RNA_POLYMERASE_II_HOLOENZYME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DIRECTED_RNA_POLYMERASE_II_HOLOENZYME","description":"Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_QUALITY_CONTROL_COMPARTMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_QUALITY_CONTROL_COMPARTMENT","description":"A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_MEMBRANE","description":"The component of the mitochondrial membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane."} {"geneset":"GO_LATERAL_ELEMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LATERAL_ELEMENT","description":"A proteinaceous core found between sister chromatids during meiotic prophase."} {"geneset":"GO_CYTOPLASMIC_VESICLE_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_VESICLE_PART","description":"Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell."} {"geneset":"GO_INTERMEDIATE_FILAMENT_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERMEDIATE_FILAMENT_CYTOSKELETON","description":"Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell."} {"geneset":"GO_ENDOSOMAL_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOSOMAL_PART","description":"Any constituent part of an endosome, a membrane-bounded organelle to which materials ingested by endocytosis are delivered."} {"geneset":"GO_ACROSOMAL_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACROSOMAL_VESICLE","description":"A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome."} {"geneset":"GO_PSEUDOPODIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PSEUDOPODIUM","description":"A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding."} {"geneset":"GO_T_TUBULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_T_TUBULE","description":"Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT","description":"A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport."} {"geneset":"GO_PLASMA_MEMBRANE_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLASMA_MEMBRANE_REGION","description":"A membrane that is a (regional) part of the plasma membrane."} {"geneset":"GO_NEURON_PROJECTION_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_MEMBRANE","description":"The portion of the plasma membrane surrounding a neuron projection."} {"geneset":"GO_INTEGRATOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTEGRATOR_COMPLEX","description":"A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II."} {"geneset":"GO_SARCOLEMMA","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SARCOLEMMA","description":"The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers."} {"geneset":"GO_IKAPPAB_KINASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IKAPPAB_KINASE_COMPLEX","description":"A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription."} {"geneset":"GO_CELL_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_BODY","description":"The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections."} {"geneset":"GO_LYTIC_VACUOLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYTIC_VACUOLE","description":"A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases."} {"geneset":"GO_CUL4_RING_E3_UBIQUITIN_LIGASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CUL4_RING_E3_UBIQUITIN_LIGASE_COMPLEX","description":"A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein."} {"geneset":"GO_CONDENSED_CHROMOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONDENSED_CHROMOSOME","description":"A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure."} {"geneset":"GO_ESC_E_Z_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESC_E_Z_COMPLEX","description":"A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4."} {"geneset":"GO_NUCLEAR_PERIPHERY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_PERIPHERY","description":"The portion of the nuclear lumen proximal to the inner nuclear membrane."} {"geneset":"GO_CULLIN_RING_UBIQUITIN_LIGASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CULLIN_RING_UBIQUITIN_LIGASE_COMPLEX","description":"Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity."} {"geneset":"GO_MAIN_AXON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAIN_AXON","description":"The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites."} {"geneset":"GO_LAMELLAR_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAMELLAR_BODY","description":"A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome."} {"geneset":"GO_CHROMATOID_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATOID_BODY","description":"A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182)."} {"geneset":"GO_CHROMOSOME_TELOMERIC_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMOSOME_TELOMERIC_REGION","description":"The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins."} {"geneset":"GO_TOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOR_COMPLEX","description":"A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K."} {"geneset":"GO_WNT_SIGNALOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WNT_SIGNALOSOME","description":"A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein."} {"geneset":"GO_ACTIN_BASED_CELL_PROJECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_BASED_CELL_PROJECTION","description":"A cell projection supported by an assembly of actin filaments, and which lacks microtubules."} {"geneset":"GO_CELL_PROJECTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PROJECTION","description":"A prolongation or process extending from a cell, e.g. a flagellum or axon."} {"geneset":"GO_REPLISOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REPLISOME","description":"A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins."} {"geneset":"GO_CILIARY_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIARY_MEMBRANE","description":"The portion of the plasma membrane surrounding a cilium."} {"geneset":"GO_COATED_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COATED_VESICLE","description":"Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins."} {"geneset":"GO_INTERCELLULAR_BRIDGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERCELLULAR_BRIDGE","description":"A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised."} {"geneset":"GO_CELL_PROJECTION_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_PROJECTION_PART","description":"Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon."} {"geneset":"GO_MHC_CLASS_II_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MHC_CLASS_II_PROTEIN_COMPLEX","description":"A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen."} {"geneset":"GO_KERATIN_FILAMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KERATIN_FILAMENT","description":"A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins."} {"geneset":"GO_RNAI_EFFECTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNAI_EFFECTOR_COMPLEX","description":"Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins."} {"geneset":"GO_PRESYNAPSE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRESYNAPSE","description":"The part of a synapse that is part of the presynaptic cell."} {"geneset":"GO_A_BAND","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_A_BAND","description":"The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line."} {"geneset":"GO_NEUROMUSCULAR_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROMUSCULAR_JUNCTION","description":"The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential."} {"geneset":"GO_SOMATODENDRITIC_COMPARTMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOMATODENDRITIC_COMPARTMENT","description":"The region of a neuron that includes the cell body (cell soma) and the dendrite, but excludes the axon."} {"geneset":"GO_PRE_AUTOPHAGOSOMAL_STRUCTURE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRE_AUTOPHAGOSOMAL_STRUCTURE_MEMBRANE","description":"A cellular membrane associated with the pre-autophagosomal structure."} {"geneset":"GO_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE","description":"The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface."} {"geneset":"GO_LYTIC_VACUOLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYTIC_VACUOLE_MEMBRANE","description":"The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell."} {"geneset":"GO_CUL3_RING_UBIQUITIN_LIGASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CUL3_RING_UBIQUITIN_LIGASE_COMPLEX","description":"A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein."} {"geneset":"GO_ENVELOPE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENVELOPE","description":"A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers."} {"geneset":"GO_PRIMARY_CILIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRIMARY_CILIUM","description":"A cilium found on many different cell types that is typically present in a single copy per cell. A primary cilium may have a variable array of axonemal microtubules and may or may not contain molecular motors."} {"geneset":"GO_RUFFLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RUFFLE","description":"Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork."} {"geneset":"GO_WASH_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WASH_COMPLEX","description":"A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53."} {"geneset":"GO_DENDRITE_CYTOPLASM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITE_CYTOPLASM","description":"All of the contents of a dendrite, excluding the surrounding plasma membrane."} {"geneset":"GO_CORNIFIED_ENVELOPE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORNIFIED_ENVELOPE","description":"A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes)."} {"geneset":"GO_PERIKARYON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERIKARYON","description":"The portion of the cell soma (cell body) that excludes the nucleus."} {"geneset":"GO_MICROBODY_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROBODY_PART","description":"Any constituent part of a microbody, a cytoplasmic organelle, spherical or oval in shape, that is bounded by a single membrane and contains oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)."} {"geneset":"GO_GOLGI_APPARATUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_APPARATUS","description":"A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions."} {"geneset":"GO_NUCLEOLUS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOLUS","description":"A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome."} {"geneset":"GO_PERICENTRIOLAR_MATERIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PERICENTRIOLAR_MATERIAL","description":"A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome."} {"geneset":"GO_TELOMERE_CAP_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERE_CAP_COMPLEX","description":"A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome."} {"geneset":"GO_NUCLEOTIDE_EXCISION_REPAIR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_EXCISION_REPAIR_COMPLEX","description":"Any complex formed of proteins that act in nucleotide-excision repair."} {"geneset":"GO_NUCLEAR_PORE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_PORE","description":"Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined."} {"geneset":"GO_AP_TYPE_MEMBRANE_COAT_ADAPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AP_TYPE_MEMBRANE_COAT_ADAPTOR_COMPLEX","description":"Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa)."} {"geneset":"GO_BAF_TYPE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BAF_TYPE_COMPLEX","description":"A SWI/SNF-type complex that contains a subunit from the BAF (Brahma-Associated Factor) family."} {"geneset":"GO_MYOSIN_II_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOSIN_II_COMPLEX","description":"A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures."} {"geneset":"GO_MICROTUBULE_ORGANIZING_CENTER_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_ORGANIZING_CENTER_PART","description":"Any constituent part of a microtubule organizing center, a region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow."} {"geneset":"GO_NUCLEAR_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_MEMBRANE","description":"Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space."} {"geneset":"GO_SWI_SNF_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SWI_SNF_COMPLEX","description":"A SWI/SNF-type complex that contains nine or more proteins, including both conserved (core) and nonconserved components; the Swi2/Snf2 ATPase is one of the core components."} {"geneset":"GO_CYTOPLASMIC_MICROTUBULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOPLASMIC_MICROTUBULE","description":"Any microtubule in the cytoplasm of a cell."} {"geneset":"GO_CLATHRIN_COAT_OF_ENDOCYTIC_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COAT_OF_ENDOCYTIC_VESICLE","description":"A clathrin coat found on an endocytic vesicle."} {"geneset":"GO_HOST","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOST","description":"Any organism in which another organism, especially a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection."} {"geneset":"GO_PIGMENT_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PIGMENT_GRANULE","description":"A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes."} {"geneset":"GO_EXTRINSIC_COMPONENT_OF_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRINSIC_COMPONENT_OF_MEMBRANE","description":"The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region."} {"geneset":"GO_SPINDLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPINDLE","description":"The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart."} {"geneset":"GO_TRANSPORT_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSPORT_VESICLE","description":"Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell."} {"geneset":"GO_TRANSCRIPTION_ELONGATION_FACTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_ELONGATION_FACTOR_COMPLEX","description":"Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation."} {"geneset":"GO_ACTIN_FILAMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT","description":"A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane."} {"geneset":"GO_INTRINSIC_COMPONENT_OF_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRINSIC_COMPONENT_OF_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE","description":"The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor."} {"geneset":"GO_CILIARY_PLASM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIARY_PLASM","description":"All of the contents of a cilium, excluding the plasma membrane surrounding the cilium."} {"geneset":"GO_SPERM_FLAGELLUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPERM_FLAGELLUM","description":"A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid."} {"geneset":"GO_GOLGI_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_LUMEN","description":"The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks."} {"geneset":"GO_ESCRT_III_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESCRT_III_COMPLEX","description":"An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes."} {"geneset":"GO_COHESIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COHESIN_COMPLEX","description":"A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3)."} {"geneset":"GO_MITOCHONDRIAL_ENVELOPE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_ENVELOPE","description":"The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space."} {"geneset":"GO_RIBONUCLEOPROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOPROTEIN_COMPLEX","description":"A macromolecular complex containing both protein and RNA molecules."} {"geneset":"GO_CELL_LEADING_EDGE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_LEADING_EDGE","description":"The area of a motile cell closest to the direction of movement."} {"geneset":"GO_CLATHRIN_COATED_ENDOCYTIC_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COATED_ENDOCYTIC_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a clathrin-coated endocytic vesicle."} {"geneset":"GO_ENDOPLASMIC_RETICULUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM","description":"The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)."} {"geneset":"GO_CALCIUM_CHANNEL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_CHANNEL_COMPLEX","description":"An ion channel complex through which calcium ions pass."} {"geneset":"GO_TRANSLATION_PREINITIATION_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATION_PREINITIATION_COMPLEX","description":"A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA."} {"geneset":"GO_MITOCHONDRIAL_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOCHONDRIAL_PROTEIN_COMPLEX","description":"A protein complex that is part of a mitochondrion."} {"geneset":"GO_MICROTUBULE_ORGANIZING_CENTER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_ORGANIZING_CENTER","description":"An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides."} {"geneset":"GO_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX","description":"A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane."} {"geneset":"GO_PROTEIN_LIPID_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LIPID_COMPLEX","description":"A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other."} {"geneset":"GO_MEMBRANE_REGION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_REGION","description":"A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane."} {"geneset":"GO_NBAF_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NBAF_COMPLEX","description":"A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth."} {"geneset":"GO_MEDIATOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEDIATOR_COMPLEX","description":"A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins."} {"geneset":"GO_CILIUM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIUM","description":"A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body."} {"geneset":"GO_EXTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE","description":"The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region."} {"geneset":"GO_AXON_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXON_PART","description":"A part of an axon, a cell projection of a neuron."} {"geneset":"GO_BRUSH_BORDER_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BRUSH_BORDER_MEMBRANE","description":"The portion of the plasma membrane surrounding the brush border."} {"geneset":"GO_TERMINAL_BOUTON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TERMINAL_BOUTON","description":"Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it."} {"geneset":"GO_ANCHORED_COMPONENT_OF_PLASMA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANCHORED_COMPONENT_OF_PLASMA_MEMBRANE","description":"The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping."} {"geneset":"GO_AXONEMAL_DYNEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AXONEMAL_DYNEIN_COMPLEX","description":"A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion."} {"geneset":"GO_MAST_CELL_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAST_CELL_GRANULE","description":"Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase."} {"geneset":"GO_RECYCLING_ENDOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECYCLING_ENDOSOME","description":"An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane."} {"geneset":"GO_COATED_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COATED_MEMBRANE","description":"A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes."} {"geneset":"GO_SYNAPSE_PART","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPSE_PART","description":"Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell."} {"geneset":"GO_EARLY_ENDOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EARLY_ENDOSOME","description":"A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways."} {"geneset":"GO_PROTEASOME_ACCESSORY_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEASOME_ACCESSORY_COMPLEX","description":"A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex."} {"geneset":"GO_CYTOSOLIC_RIBOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSOLIC_RIBOSOME","description":"A ribosome located in the cytosol."} {"geneset":"GO_PHOTORECEPTOR_DISC_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_DISC_MEMBRANE","description":"Ovally-shaped membranous stack located inside the photoreceptor outer segment, and containing densely packed molecules of the photoreceptor protein rhodopsin that traverse the lipid bilayer. Disc membranes are apparently derived from the plasma membrane in the region of the cilium that connects the photoreceptor outer segment to the inner segment."} {"geneset":"GO_PROTEIN_PHOSPHATASE_TYPE_2A_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_PHOSPHATASE_TYPE_2A_COMPLEX","description":"A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit."} {"geneset":"GO_CILIARY_BASAL_BODY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CILIARY_BASAL_BODY","description":"A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport."} {"geneset":"GO_TRANS_GOLGI_NETWORK_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANS_GOLGI_NETWORK_MEMBRANE","description":"The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network."} {"geneset":"GO_ENDOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOSOME","description":"A vacuole to which materials ingested by endocytosis are delivered."} {"geneset":"GO_TRANSPORT_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSPORT_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding a transport vesicle."} {"geneset":"GO_NEURONAL_CELL_BODY_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURONAL_CELL_BODY_MEMBRANE","description":"The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites."} {"geneset":"GO_HISTONE_DEACETYLASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_DEACETYLASE_COMPLEX","description":"A protein complex that possesses histone deacetylase activity."} {"geneset":"GO_PHOTORECEPTOR_OUTER_SEGMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_OUTER_SEGMENT","description":"The outer segment of a vertebrate photoreceptor that contains discs of photoreceptive membranes."} {"geneset":"GO_U12_TYPE_SPLICEOSOMAL_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_U12_TYPE_SPLICEOSOMAL_COMPLEX","description":"Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site."} {"geneset":"GO_BASAL_PART_OF_CELL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASAL_PART_OF_CELL","description":"The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue."} {"geneset":"GO_SODIUM_POTASSIUM_EXCHANGING_ATPASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_POTASSIUM_EXCHANGING_ATPASE_COMPLEX","description":"Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior."} {"geneset":"GO_SITE_OF_DOUBLE_STRAND_BREAK","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SITE_OF_DOUBLE_STRAND_BREAK","description":"A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix."} {"geneset":"GO_PLASMA_MEMBRANE_RAFT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLASMA_MEMBRANE_RAFT","description":"A membrane raft that is part of the plasma membrane."} {"geneset":"GO_MICROBODY_LUMEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROBODY_LUMEN","description":"The volume enclosed by the membranes of a microbody."} {"geneset":"GO_FILAMENTOUS_ACTIN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FILAMENTOUS_ACTIN","description":"A two-stranded helical polymer of the protein actin."} {"geneset":"GO_METHYLOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METHYLOSOME","description":"A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains."} {"geneset":"GO_GOLGI_CISTERNA_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GOLGI_CISTERNA_MEMBRANE","description":"The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex."} {"geneset":"GO_PROTON_TRANSPORTING_ATP_SYNTHASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTON_TRANSPORTING_ATP_SYNTHASE_COMPLEX","description":"A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient."} {"geneset":"GO_PLASMA_MEMBRANE_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLASMA_MEMBRANE_PROTEIN_COMPLEX","description":"Any protein complex that is part of the plasma membrane."} {"geneset":"GO_CENTRIOLAR_SATELLITE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CENTRIOLAR_SATELLITE","description":"A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome."} {"geneset":"GO_CLATHRIN_ADAPTOR_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_ADAPTOR_COMPLEX","description":"A membrane coat adaptor complex that links clathrin to a membrane."} {"geneset":"GO_GAP_JUNCTION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GAP_JUNCTION","description":"A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2-4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons."} {"geneset":"GO_DERLIN_1_RETROTRANSLOCATION_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DERLIN_1_RETROTRANSLOCATION_COMPLEX","description":"A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel."} {"geneset":"GO_PLATELET_DENSE_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_DENSE_GRANULE","description":"Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins."} {"geneset":"GO_DENSE_CORE_GRANULE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENSE_CORE_GRANULE","description":"Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted."} {"geneset":"GO_SYNAPTIC_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPTIC_MEMBRANE","description":"A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell."} {"geneset":"GO_EXOCYTIC_VESICLE_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXOCYTIC_VESICLE_MEMBRANE","description":"The lipid bilayer surrounding an exocytic vesicle"} {"geneset":"GO_ACETYLTRANSFERASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACETYLTRANSFERASE_COMPLEX","description":"A protein complex which is capable of acetyltransferase activity."} {"geneset":"GO_ANCHORED_COMPONENT_OF_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANCHORED_COMPONENT_OF_MEMBRANE","description":"The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping."} {"geneset":"GO_MHC_CLASS_I_PROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MHC_CLASS_I_PROTEIN_COMPLEX","description":"A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules."} {"geneset":"GO_DENDRITE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DENDRITE","description":"A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body."} {"geneset":"GO_NUCLEAR_UBIQUITIN_LIGASE_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_UBIQUITIN_LIGASE_COMPLEX","description":"A ubiquitin ligase complex found in the nucleus."} {"geneset":"GO_ORGANELLE_SUBCOMPARTMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANELLE_SUBCOMPARTMENT","description":"A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle."} {"geneset":"GO_CLATHRIN_COAT_OF_TRANS_GOLGI_NETWORK_VESICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_COAT_OF_TRANS_GOLGI_NETWORK_VESICLE","description":"A clathrin coat found on a vesicle of the trans-Golgi network."} {"geneset":"GO_CHYLOMICRON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHYLOMICRON","description":"A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues."} {"geneset":"GO_PRIMARY_LYSOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRIMARY_LYSOSOME","description":"A lysosome before it has fused with a vesicle or vacuole."} {"geneset":"GO_TRIGLYCERIDE_RICH_LIPOPROTEIN_PARTICLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRIGLYCERIDE_RICH_LIPOPROTEIN_PARTICLE","description":"A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoproteinparticles transport lipids, which are non-covalently associated with the particles, in the blood."} {"geneset":"GO_ENDOPLASMIC_RETICULUM_SUBCOMPARTMENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_SUBCOMPARTMENT","description":"A distinct region of the endoplasmic reticulum"} {"geneset":"GO_COLLAGEN_TRIMER","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COLLAGEN_TRIMER","description":"A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures."} {"geneset":"GO_SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX","description":"A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs."} {"geneset":"GO_CYCLIN_DEPENDENT_PROTEIN_KINASE_HOLOENZYME_COMPLEX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIN_DEPENDENT_PROTEIN_KINASE_HOLOENZYME_COMPLEX","description":"Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner."} {"geneset":"GO_VACUOLAR_MEMBRANE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLAR_MEMBRANE","description":"The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell."} {"geneset":"GO_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY","description":"Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate."} {"geneset":"GO_PROTEIN_SERINE_THREONINE_TYROSINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SERINE_THREONINE_TYROSINE_KINASE_ACTIVITY","description":"Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate."} {"geneset":"GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_CYCLIC_AMIDINES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_CYCLIC_AMIDINES","description":"Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2."} {"geneset":"GO_5_3_EXONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_5_3_EXONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end."} {"geneset":"GO_POLYUBIQUITIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYUBIQUITIN_BINDING","description":"Interacting selectively and non-covalently with a polymer of ubiqutin."} {"geneset":"GO_COFACTOR_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COFACTOR_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of a cofactor into, out of or within a cell, or between cells. A cofactor is a substance that is required for the activity of an enzyme or other protein."} {"geneset":"GO_BETA_CATENIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_CATENIN_BINDING","description":"Interacting selectively and non-covalently with the beta subunit of the catenin complex."} {"geneset":"GO_UDP_GALACTOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UDP_GALACTOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule."} {"geneset":"GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_BINDING","description":"Interacting selectively and non-covalently with a mitogen-activated protein kinase."} {"geneset":"GO_PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of phosphate from one side of the membrane to the other."} {"geneset":"GO_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid."} {"geneset":"GO_IMMUNOGLOBULIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNOGLOBULIN_BINDING","description":"Interacting selectively and non-covalently with an immunoglobulin."} {"geneset":"GO_PROTEIN_KINASE_A_REGULATORY_SUBUNIT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_A_REGULATORY_SUBUNIT_BINDING","description":"Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A."} {"geneset":"GO_SIGNAL_TRANSDUCER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_TRANSDUCER_ACTIVITY","description":"Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response."} {"geneset":"GO_MHC_PROTEIN_COMPLEX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MHC_PROTEIN_COMPLEX_BINDING","description":"Interacting selectively and non-covalently with the major histocompatibility complex."} {"geneset":"GO_IONOTROPIC_GLUTAMATE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IONOTROPIC_GLUTAMATE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels."} {"geneset":"GO_UBIQUITIN_LIKE_PROTEIN_TRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_LIKE_PROTEIN_TRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein."} {"geneset":"GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY","description":"Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP."} {"geneset":"GO_SMAD_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SMAD_BINDING","description":"Interacting selectively and non-covalently with a SMAD signaling protein."} {"geneset":"GO_SYNTAXIN_1_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNTAXIN_1_BINDING","description":"Interacting selectively and non-covalently with the SNAP receptor syntaxin-1."} {"geneset":"GO_LONG_CHAIN_FATTY_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LONG_CHAIN_FATTY_ACID_BINDING","description":"Interacting selectively and non-covalently with a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."} {"geneset":"GO_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP."} {"geneset":"GO_ACTIVE_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVE_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Catalysis of the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction."} {"geneset":"GO_CYTOKINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_BINDING","description":"Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity."} {"geneset":"GO_NEUROTRANSMITTER_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTRANSMITTER_BINDING","description":"Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell."} {"geneset":"GO_OLFACTORY_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLFACTORY_RECEPTOR_ACTIVITY","description":"Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell."} {"geneset":"GO_SERINE_TYPE_EXOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SERINE_TYPE_EXOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."} {"geneset":"GO_3_5_CYCLIC_AMP_PHOSPHODIESTERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_3_5_CYCLIC_AMP_PHOSPHODIESTERASE_ACTIVITY","description":"Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate."} {"geneset":"GO_VOLTAGE_GATED_ION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_ION_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_5_BISPHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_5_BISPHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions."} {"geneset":"GO_PROTEIN_KINASE_C_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_C_BINDING","description":"Interacting selectively and non-covalently with protein kinase C."} {"geneset":"GO_BETA_2_MICROGLOBULIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_2_MICROGLOBULIN_BINDING","description":"Interacting selectively and non-covalently with beta-2-microglobulin."} {"geneset":"GO_PROTEIN_COMPLEX_SCAFFOLD","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_COMPLEX_SCAFFOLD","description":"Functions to provide a physical support for the assembly of a multiprotein complex."} {"geneset":"GO_HEAT_SHOCK_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEAT_SHOCK_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock."} {"geneset":"GO_PHOSPHOPROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOPROTEIN_BINDING","description":"Interacting selectively and non-covalently with a phosphorylated protein."} {"geneset":"GO_GTPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GTPASE_ACTIVITY","description":"Catalysis of the reaction: GTP + H2O = GDP + phosphate."} {"geneset":"GO_AMINO_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_ACID_BINDING","description":"Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS","description":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_HEME_GROUP_OF_DONORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_HEME_GROUP_OF_DONORS","description":"Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."} {"geneset":"GO_QUINONE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_QUINONE_BINDING","description":"Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds."} {"geneset":"GO_G_PROTEIN_ALPHA_SUBUNIT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_ALPHA_SUBUNIT_BINDING","description":"Interacting selectively and non-covalently with a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide."} {"geneset":"GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_KINASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_KINASE_BINDING","description":"Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase."} {"geneset":"GO_PEPTIDASE_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDASE_REGULATOR_ACTIVITY","description":"Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds."} {"geneset":"GO_CYTOSKELETAL_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSKELETAL_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)."} {"geneset":"GO_VITAMIN_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VITAMIN_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of vitamins into, out of or within a cell, or between cells. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_SULFUR_CONTAINING_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_SULFUR_CONTAINING_GROUPS","description":"Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor)."} {"geneset":"GO_CYCLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLASE_ACTIVITY","description":"Catalysis of a ring closure reaction."} {"geneset":"GO_PROTEIN_SELF_ASSOCIATION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SELF_ASSOCIATION","description":"Interacting selectively and non-covalently with a domain within the same polypeptide."} {"geneset":"GO_CYSTEINE_TYPE_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYSTEINE_TYPE_PEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."} {"geneset":"GO_LIPID_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of lipids into, out of or within a cell, or between cells."} {"geneset":"GO_ENDODEOXYRIBONUCLEASE_ACTIVITY_PRODUCING_5_PHOSPHOMONOESTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDODEOXYRIBONUCLEASE_ACTIVITY_PRODUCING_5_PHOSPHOMONOESTERS","description":"Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters."} {"geneset":"GO_SULFUR_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFUR_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a sulfur compound from one side of the membrane to the other."} {"geneset":"GO_DNA_POLYMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_POLYMERASE_ACTIVITY","description":"Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group."} {"geneset":"GO_HISTONE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_BINDING","description":"Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity."} {"geneset":"GO_UBIQUITIN_LIKE_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_LIKE_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein."} {"geneset":"GO_DNA_BINDING_BENDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_BINDING_BENDING","description":"The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence."} {"geneset":"GO_RNA_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule."} {"geneset":"GO_CYCLIC_NUCLEOTIDE_GATED_ION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIC_NUCLEOTIDE_GATED_ION_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_NARROW_PORE_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NARROW_PORE_CHANNEL_ACTIVITY","description":"Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated."} {"geneset":"GO_STEROID_DEHYDROGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_DEHYDROGENASE_ACTIVITY","description":"Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative."} {"geneset":"GO_BHLH_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BHLH_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways."} {"geneset":"GO_G_PROTEIN_COUPLED_NEUROTRANSMITTER_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_NEUROTRANSMITTER_RECEPTOR_ACTIVITY","description":"Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."} {"geneset":"GO_METHYLATED_HISTONE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METHYLATED_HISTONE_BINDING","description":"Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes."} {"geneset":"GO_ATP_DEPENDENT_DNA_HELICASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATP_DEPENDENT_DNA_HELICASE_ACTIVITY","description":"Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix."} {"geneset":"GO_PURINE_NTP_DEPENDENT_HELICASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PURINE_NTP_DEPENDENT_HELICASE_ACTIVITY","description":"Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix."} {"geneset":"GO_PROTEIN_BINDING_INVOLVED_IN_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_BINDING_INVOLVED_IN_CELL_ADHESION","description":"Any protein binding that is involved in cell adhesion."} {"geneset":"GO_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR)."} {"geneset":"GO_VOLTAGE_GATED_ANION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_ANION_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."} {"geneset":"GO_RNA_POLYMERASE_II_TRANSCRIPTION_COREPRESSOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_TRANSCRIPTION_COREPRESSOR_ACTIVITY","description":"Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery."} {"geneset":"GO_PHOSPHATASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule."} {"geneset":"GO_MAGNESIUM_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAGNESIUM_ION_BINDING","description":"Interacting selectively and non-covalently with magnesium (Mg) ions."} {"geneset":"GO_DNA_SECONDARY_STRUCTURE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_SECONDARY_STRUCTURE_BINDING","description":"Interacting selectively and non-covalently with DNA containing secondary structure elements such as four-way junctions, bubbles, loops, Y-form DNA, or double-strand/single-strand junctions."} {"geneset":"GO_SULFUR_COMPOUND_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFUR_COMPOUND_BINDING","description":"Interacting selectively and non-covalently with a sulfur compound."} {"geneset":"GO_SIGNAL_SEQUENCE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNAL_SEQUENCE_BINDING","description":"Interacting selectively and non-covalently with a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_OH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_OH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP."} {"geneset":"GO_SYNTAXIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNTAXIN_BINDING","description":"Interacting selectively and non-covalently with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse."} {"geneset":"GO_HEPARAN_SULFATE_SULFOTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEPARAN_SULFATE_SULFOTRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate."} {"geneset":"GO_CARBOHYDRATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_BINDING","description":"Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates."} {"geneset":"GO_TAU_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TAU_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS."} {"geneset":"GO_ACYLGLYCEROL_O_ACYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACYLGLYCEROL_O_ACYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule."} {"geneset":"GO_COMPLEMENT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COMPLEMENT_BINDING","description":"Interacting selectively and non-covalently with any component or product of the complement cascade."} {"geneset":"GO_HORMONE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HORMONE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a receptor for hormones."} {"geneset":"GO_DIVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of inorganic cations with a valency of two from one side of the membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."} {"geneset":"GO_PROTEIN_HETERODIMERIZATION_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HETERODIMERIZATION_ACTIVITY","description":"Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer."} {"geneset":"GO_PROTEIN_PHOSPHATASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_PHOSPHATASE_BINDING","description":"Interacting selectively and non-covalently with any protein phosphatase."} {"geneset":"GO_MONOVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."} {"geneset":"GO_3_5_CYCLIC_GMP_PHOSPHODIESTERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_3_5_CYCLIC_GMP_PHOSPHODIESTERASE_ACTIVITY","description":"Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate."} {"geneset":"GO_VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."} {"geneset":"GO_PROTEIN_TYROSINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TYROSINE_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate."} {"geneset":"GO_TRANSMITTER_GATED_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMITTER_GATED_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_PROTEIN_DEACETYLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DEACETYLASE_ACTIVITY","description":"Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate."} {"geneset":"GO_ENDONUCLEASE_ACTIVITY_ACTIVE_WITH_EITHER_RIBO_OR_DEOXYRIBONUCLEIC_ACIDS_AND_PRODUCING_3_PHOSPHOMONOESTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDONUCLEASE_ACTIVITY_ACTIVE_WITH_EITHER_RIBO_OR_DEOXYRIBONUCLEIC_ACIDS_AND_PRODUCING_3_PHOSPHOMONOESTERS","description":"Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters."} {"geneset":"GO_SODIUM_AMINO_ACID_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_AMINO_ACID_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in)."} {"geneset":"GO_FATTY_ACYL_COA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACYL_COA_BINDING","description":"Interacting selectively and non-covalently with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_5_BISPHOSPHATE_3_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_5_BISPHOSPHATE_3_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+."} {"geneset":"GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING","description":"Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."} {"geneset":"GO_CYCLIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIN_BINDING","description":"Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis."} {"geneset":"GO_ACID_AMINO_ACID_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACID_AMINO_ACID_LIGASE_ACTIVITY","description":"Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H","description":"Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."} {"geneset":"GO_CORE_PROMOTER_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORE_PROMOTER_BINDING","description":"Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors."} {"geneset":"GO_NEUROPEPTIDE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROPEPTIDE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a neuropeptide receptor."} {"geneset":"GO_RETINOIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINOIC_ACID_BINDING","description":"Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid."} {"geneset":"GO_DIACYLGLYCEROL_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIACYLGLYCEROL_KINASE_ACTIVITY","description":"Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate."} {"geneset":"GO_STEROID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_BINDING","description":"Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene."} {"geneset":"GO_LEUCINE_ZIPPER_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LEUCINE_ZIPPER_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_5_PHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_5_PHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position."} {"geneset":"GO_I_SMAD_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_I_SMAD_BINDING","description":"Interacting selectively and non-covalently with an inhibitory SMAD signaling protein."} {"geneset":"GO_ENHANCER_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENHANCER_BINDING","description":"Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter."} {"geneset":"GO_DEMETHYLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEMETHYLASE_ACTIVITY","description":"Catalysis of the removal of a methyl group from a substrate."} {"geneset":"GO_RAC_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAC_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","description":"Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rac family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."} {"geneset":"GO_PROTEIN_BINDING_INVOLVED_IN_PROTEIN_FOLDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_BINDING_INVOLVED_IN_PROTEIN_FOLDING","description":"Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding."} {"geneset":"GO_KINASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule."} {"geneset":"GO_PHOTORECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOTORECEPTOR_ACTIVITY","description":"The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation."} {"geneset":"GO_CYTOSKELETAL_ADAPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOSKELETAL_ADAPTOR_ACTIVITY","description":"The binding activity of a molecule that brings together a cytoskeletal protein and one or more other molecules, permitting them to function in a coordinated way."} {"geneset":"GO_TRANSCRIPTION_FACTOR_ACTIVITY_DIRECT_LIGAND_REGULATED_SEQUENCE_SPECIFIC_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_ACTIVITY_DIRECT_LIGAND_REGULATED_SEQUENCE_SPECIFIC_DNA_BINDING","description":"A DNA binding transcription factor activity that is directly regulated by binding of a ligand to the protein with this activity. Examples include the lac and trp repressors in E.coli and many steroid hormone receptors."} {"geneset":"GO_RACEMASE_AND_EPIMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RACEMASE_AND_EPIMERASE_ACTIVITY","description":"Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule."} {"geneset":"GO_PROTEIN_LIPID_COMPLEX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_LIPID_COMPLEX_BINDING","description":"Interacting selectively and non-covalently with a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules."} {"geneset":"GO_CARBOXY_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOXY_LYASE_ACTIVITY","description":"Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound."} {"geneset":"GO_MIRNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MIRNA_BINDING","description":"Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes."} {"geneset":"GO_ESTROGEN_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTROGEN_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with an estrogen receptor."} {"geneset":"GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING","description":"Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter."} {"geneset":"GO_UBIQUITIN_UBIQUITIN_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_UBIQUITIN_LIGASE_ACTIVITY","description":"Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue."} {"geneset":"GO_FMN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FMN_BINDING","description":"Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes."} {"geneset":"GO_ADENYLYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADENYLYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an adenylyl group to an acceptor."} {"geneset":"GO_ATPASE_ACTIVITY_COUPLED","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_ACTIVITY_COUPLED","description":"Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane."} {"geneset":"GO_S_ACYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_S_ACYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule."} {"geneset":"GO_ANKYRIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANKYRIN_BINDING","description":"Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins."} {"geneset":"GO_PROTEASOME_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEASOME_BINDING","description":"Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation."} {"geneset":"GO_DNA_N_GLYCOSYLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_N_GLYCOSYLASE_ACTIVITY","description":"Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_MONOPHOSPHATE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_MONOPHOSPHATE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate."} {"geneset":"GO_PROTEIN_DIMERIZATION_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DIMERIZATION_ACTIVITY","description":"The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ALKYL_OR_ARYL_OTHER_THAN_METHYL_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ALKYL_OR_ARYL_OTHER_THAN_METHYL_GROUPS","description":"Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor)."} {"geneset":"GO_UNFOLDED_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UNFOLDED_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with an unfolded protein."} {"geneset":"GO_POLY_A_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLY_A_BINDING","description":"Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA."} {"geneset":"GO_ATPASE_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_ACTIVATOR_ACTIVITY","description":"Binds to and increases the ATP hydrolysis activity of an ATPase."} {"geneset":"GO_CARBOHYDRATE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate."} {"geneset":"GO_VIRUS_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VIRUS_RECEPTOR_ACTIVITY","description":"Combining with a virus component and mediating entry of the virus into the cell."} {"geneset":"GO_NUCLEOSOME_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSOME_BINDING","description":"Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures."} {"geneset":"GO_UBIQUITIN_LIKE_PROTEIN_CONJUGATING_ENZYME_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_LIKE_PROTEIN_CONJUGATING_ENZYME_ACTIVITY","description":"Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue."} {"geneset":"GO_ATP_DEPENDENT_MICROTUBULE_MOTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATP_DEPENDENT_MICROTUBULE_MOTOR_ACTIVITY","description":"Catalysis of movement along a microtubule, coupled to the hydrolysis of ATP."} {"geneset":"GO_C2H2_ZINC_FINGER_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_C2H2_ZINC_FINGER_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion."} {"geneset":"GO_CALCIUM_ACTIVATED_POTASSIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ACTIVATED_POTASSIUM_CHANNEL_ACTIVITY","description":"Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient."} {"geneset":"GO_ACTIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_BINDING","description":"Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_4_5_BISPHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_4_5_BISPHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions."} {"geneset":"GO_PRENYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRENYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor)."} {"geneset":"GO_ANION_CATION_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANION_CATION_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in)."} {"geneset":"GO_LYSINE_ACETYLATED_HISTONE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSINE_ACETYLATED_HISTONE_BINDING","description":"Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation."} {"geneset":"GO_PEPTIDE_HORMONE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_HORMONE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a receptor for peptide hormones."} {"geneset":"GO_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage."} {"geneset":"GO_PROTEIN_KINASE_A_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_A_BINDING","description":"Interacting selectively and non-covalently with any subunit of protein kinase A."} {"geneset":"GO_MANNOSIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MANNOSIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative."} {"geneset":"GO_KINASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINASE_BINDING","description":"Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group."} {"geneset":"GO_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of metal ions from one side of a membrane to the other."} {"geneset":"GO_COA_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COA_HYDROLASE_ACTIVITY","description":"Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group."} {"geneset":"GO_ADRENERGIC_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADRENERGIC_RECEPTOR_ACTIVITY","description":"Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex."} {"geneset":"GO_GATED_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GATED_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus."} {"geneset":"GO_RNA_DNA_HYBRID_RIBONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_DNA_HYBRID_RIBONUCLEASE_ACTIVITY","description":"Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters."} {"geneset":"GO_HISTONE_DEACETYLASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_DEACETYLASE_BINDING","description":"Interacting selectively and non-covalently with the enzyme histone deacetylase."} {"geneset":"GO_ACTIN_FILAMENT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT_BINDING","description":"Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits."} {"geneset":"GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_LINEAR_AMIDINES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_LINEAR_AMIDINES","description":"Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2."} {"geneset":"GO_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_ACTIVITY","description":"Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP."} {"geneset":"GO_HEPARIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEPARIN_BINDING","description":"Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."} {"geneset":"GO_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the epidermal growth factor receptor."} {"geneset":"GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_BINDING","description":"Interacting selectively and non-covalently with a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm."} {"geneset":"GO_SERINE_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SERINE_HYDROLASE_ACTIVITY","description":"Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."} {"geneset":"GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY","description":"Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate."} {"geneset":"GO_WNT_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WNT_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with Wnt-protein, a secreted growth factor involved in signaling."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS","description":"Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor)."} {"geneset":"GO_ARYL_SULFOTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARYL_SULFOTRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate."} {"geneset":"GO_PROTEIN_SERINE_THREONINE_PHOSPHATASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SERINE_THREONINE_PHOSPHATASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate."} {"geneset":"GO_HYDRO_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDRO_LYASE_ACTIVITY","description":"Catalysis of the cleavage of a carbon-oxygen bond by elimination of water."} {"geneset":"GO_TRANSLATION_INITIATION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATION_INITIATION_FACTOR_ACTIVITY","description":"Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide."} {"geneset":"GO_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a lipoprotein particle receptor."} {"geneset":"GO_LIGAND_GATED_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGAND_GATED_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_RHO_GTPASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RHO_GTPASE_BINDING","description":"Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton."} {"geneset":"GO_PROTEIN_HOMODIMERIZATION_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HOMODIMERIZATION_ACTIVITY","description":"Interacting selectively and non-covalently with an identical protein to form a homodimer."} {"geneset":"GO_POLY_PYRIMIDINE_TRACT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLY_PYRIMIDINE_TRACT_BINDING","description":"Interacting selectively and non-covalently with any stretch of pyrimidines (cytosine or uracil) in an RNA molecule."} {"geneset":"GO_PROTEIN_PHOSPHORYLATED_AMINO_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_PHOSPHORYLATED_AMINO_ACID_BINDING","description":"Interacting selectively and non-covalently with a phosphorylated amino acid residue within a protein."} {"geneset":"GO_COLLAGEN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COLLAGEN_BINDING","description":"Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)."} {"geneset":"GO_REGULATORY_REGION_NUCLEIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATORY_REGION_NUCLEIC_ACID_BINDING","description":"Interacting selectively and non-covalently with a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair."} {"geneset":"GO_TRIGLYCERIDE_LIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRIGLYCERIDE_LIPASE_ACTIVITY","description":"Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate."} {"geneset":"GO_N_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_N_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule."} {"geneset":"GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING","description":"Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."} {"geneset":"GO_L_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_L_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids."} {"geneset":"GO_ACETYLCHOLINE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACETYLCHOLINE_RECEPTOR_ACTIVITY","description":"Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."} {"geneset":"GO_CALCIUM_ACTIVATED_CATION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ACTIVATED_CATION_CHANNEL_ACTIVITY","description":"Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient."} {"geneset":"GO_KINASE_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINASE_REGULATOR_ACTIVITY","description":"Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule."} {"geneset":"GO_ENDONUCLEASE_ACTIVITY_ACTIVE_WITH_EITHER_RIBO_OR_DEOXYRIBONUCLEIC_ACIDS_AND_PRODUCING_5_PHOSPHOMONOESTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDONUCLEASE_ACTIVITY_ACTIVE_WITH_EITHER_RIBO_OR_DEOXYRIBONUCLEIC_ACIDS_AND_PRODUCING_5_PHOSPHOMONOESTERS","description":"Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters."} {"geneset":"GO_CARBOXYPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOXYPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide."} {"geneset":"GO_ATPASE_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_REGULATOR_ACTIVITY","description":"Modulates the rate of ATP hydrolysis by an ATPase."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol phosphate."} {"geneset":"GO_GTPASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GTPASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_5_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_5_PHOSPHATASE_ACTIVITY","description":"Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate."} {"geneset":"GO_ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS_PHOSPHORYLATIVE_MECHANISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS_PHOSPHORYLATIVE_MECHANISM","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate."} {"geneset":"GO_GLUCOSIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOSIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative."} {"geneset":"GO_ORGANIC_HYDROXY_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_HYDROXY_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of organic hydroxy compound from one side of the membrane to the other."} {"geneset":"GO_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT","description":"The action of a molecule that contributes to the structural integrity of the extracellular matrix."} {"geneset":"GO_SOLUTE_PROTON_ANTIPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOLUTE_PROTON_ANTIPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out)."} {"geneset":"GO_ACIDIC_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACIDIC_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have a pH below 7."} {"geneset":"GO_ENDORIBONUCLEASE_ACTIVITY_PRODUCING_5_PHOSPHOMONOESTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDORIBONUCLEASE_ACTIVITY_PRODUCING_5_PHOSPHOMONOESTERS","description":"Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters."} {"geneset":"GO_LYSOPHOSPHOLIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSOPHOSPHOLIPASE_ACTIVITY","description":"Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate."} {"geneset":"GO_ADRENERGIC_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADRENERGIC_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with an adrenergic receptor."} {"geneset":"GO_NUCLEOSIDE_DIPHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_DIPHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate."} {"geneset":"GO_ACETYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACETYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an acetyl group to an acceptor molecule."} {"geneset":"GO_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient."} {"geneset":"GO_RNA_POLYMERASE_II_CORE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_CORE_BINDING","description":"Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits."} {"geneset":"GO_MRNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_BINDING","description":"Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns."} {"geneset":"GO_MHC_CLASS_II_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MHC_CLASS_II_RECEPTOR_ACTIVITY","description":"Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."} {"geneset":"GO_NEUROPEPTIDE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROPEPTIDE_RECEPTOR_ACTIVITY","description":"Combining with a neuropeptide to initiate a change in cell activity."} {"geneset":"GO_EXTRACELLULAR_MATRIX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_MATRIX_BINDING","description":"Interacting selectively and non-covalently with a component of the extracellular matrix."} {"geneset":"GO_SEROTONIN_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEROTONIN_RECEPTOR_ACTIVITY","description":"Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates."} {"geneset":"GO_METALLOEXOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METALLOEXOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."} {"geneset":"GO_TRNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_BINDING","description":"Interacting selectively and non-covalently with transfer RNA."} {"geneset":"GO_CALCIUM_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ION_BINDING","description":"Interacting selectively and non-covalently with calcium ions (Ca2+)."} {"geneset":"GO_NITRIC_OXIDE_SYNTHASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NITRIC_OXIDE_SYNTHASE_BINDING","description":"Interacting selectively and non-covalently with the enzyme nitric-oxide synthase."} {"geneset":"GO_PROTEIN_C_TERMINUS_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_C_TERMINUS_BINDING","description":"Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue."} {"geneset":"GO_GLYCINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCINE_BINDING","description":"Interacting selectively and non-covalently with glycine, aminoethanoic acid."} {"geneset":"GO_THIOLESTER_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THIOLESTER_HYDROLASE_ACTIVITY","description":"Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A."} {"geneset":"GO_INSULIN_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INSULIN_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the insulin receptor."} {"geneset":"GO_R_SMAD_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_R_SMAD_BINDING","description":"Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein."} {"geneset":"GO_CIS_TRANS_ISOMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CIS_TRANS_ISOMERASE_ACTIVITY","description":"Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers."} {"geneset":"GO_METALLOCARBOXYPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METALLOCARBOXYPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."} {"geneset":"GO_ALDEHYDE_DEHYDROGENASE_NAD_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALDEHYDE_DEHYDROGENASE_NAD_ACTIVITY","description":"Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_2_OXOGLUTARATE_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_EACH_OF_OXYGEN_INTO_BOTH_DONORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_2_OXOGLUTARATE_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_EACH_OF_OXYGEN_INTO_BOTH_DONORS","description":"Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor."} {"geneset":"GO_PHOSPHATE_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATE_ION_BINDING","description":"Interacting selectively and non-covalently with phosphate."} {"geneset":"GO_NUCLEOSIDE_DIPHOSPHATE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_DIPHOSPHATE_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate."} {"geneset":"GO_FAD_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FAD_BINDING","description":"Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes."} {"geneset":"GO_CLATHRIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_BINDING","description":"Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles."} {"geneset":"GO_CATION_CATION_ANTIPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_CATION_ANTIPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out)."} {"geneset":"GO_PROTEASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEASE_BINDING","description":"Interacting selectively and non-covalently with any protease or peptidase."} {"geneset":"GO_RAN_GTPASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAN_GTPASE_BINDING","description":"Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly."} {"geneset":"GO_ANTIPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIPORTER_ACTIVITY","description":"Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out)."} {"geneset":"GO_AMMONIUM_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMMONIUM_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals."} {"geneset":"GO_PHOSPHATASE_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATASE_ACTIVATOR_ACTIVITY","description":"Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule."} {"geneset":"GO_FATTY_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_BINDING","description":"Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."} {"geneset":"GO_AMINOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain."} {"geneset":"GO_NADPH_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NADPH_BINDING","description":"Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions."} {"geneset":"GO_SINGLE_STRANDED_RNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_STRANDED_RNA_BINDING","description":"Interacting selectively and non-covalently with single-stranded RNA."} {"geneset":"GO_CATECHOLAMINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATECHOLAMINE_BINDING","description":"Interacting selectively and non-covalently with catecholamine."} {"geneset":"GO_CALCIUM_DEPENDENT_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_DEPENDENT_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium."} {"geneset":"GO_NUCLEOCYTOPLASMIC_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOCYTOPLASMIC_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of substances between the nucleus and the cytoplasm of a cell."} {"geneset":"GO_GLUTATHIONE_PEROXIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTATHIONE_PEROXIDASE_ACTIVITY","description":"Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O."} {"geneset":"GO_PSEUDOURIDINE_SYNTHASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PSEUDOURIDINE_SYNTHASE_ACTIVITY","description":"Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5."} {"geneset":"GO_G_PROTEIN_COUPLED_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_RECEPTOR_ACTIVITY","description":"Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."} {"geneset":"GO_MAP_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAP_KINASE_ACTIVITY","description":"Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli."} {"geneset":"GO_NEUROPEPTIDE_HORMONE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROPEPTIDE_HORMONE_ACTIVITY","description":"The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones."} {"geneset":"GO_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of cation from one side of the membrane to the other."} {"geneset":"GO_CHANNEL_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHANNEL_REGULATOR_ACTIVITY","description":"Modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel."} {"geneset":"GO_INOSITOL_TETRAKISPHOSPHATE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_TETRAKISPHOSPHATE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate."} {"geneset":"GO_PHOSPHOLIPASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPASE_BINDING","description":"Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid."} {"geneset":"GO_STRUCTURAL_CONSTITUENT_OF_EYE_LENS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRUCTURAL_CONSTITUENT_OF_EYE_LENS","description":"The action of a molecule that contributes to the structural integrity of the lens of an eye."} {"geneset":"GO_DISULFIDE_OXIDOREDUCTASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DISULFIDE_OXIDOREDUCTASE_ACTIVITY","description":"Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds."} {"geneset":"GO_GDP_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GDP_BINDING","description":"Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate."} {"geneset":"GO_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY","description":"Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group."} {"geneset":"GO_S100_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_S100_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS."} {"geneset":"GO_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINASE_ACTIVITY","description":"Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."} {"geneset":"GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING","description":"Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II."} {"geneset":"GO_CARBOHYDRATE_DERIVATIVE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_DERIVATIVE_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of carbohydrate derivative into, out of or within a cell, or between cells."} {"geneset":"GO_SERINE_TYPE_CARBOXYPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SERINE_TYPE_CARBOXYPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."} {"geneset":"GO_HORMONE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HORMONE_ACTIVITY","description":"The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process."} {"geneset":"GO_STEROID_HORMONE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_HORMONE_RECEPTOR_ACTIVITY","description":"Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function."} {"geneset":"GO_ANDROGEN_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANDROGEN_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with an androgen receptor."} {"geneset":"GO_AMIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of the membrane to the other."} {"geneset":"GO_MANGANESE_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MANGANESE_ION_BINDING","description":"Interacting selectively and non-covalently with manganese (Mn) ions."} {"geneset":"GO_RNA_CAP_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_CAP_BINDING","description":"Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule."} {"geneset":"GO_SCAVENGER_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SCAVENGER_RECEPTOR_ACTIVITY","description":"Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, beta-amyloid fibrils, and advanced glycation end products (AGEs)."} {"geneset":"GO_CYCLIN_DEPENDENT_PROTEIN_SERINE_THREONINE_KINASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIN_DEPENDENT_PROTEIN_SERINE_THREONINE_KINASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase."} {"geneset":"GO_ICOSANOID_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ICOSANOID_RECEPTOR_ACTIVITY","description":"Combining with an icosanoid to initiate a change in cell activity."} {"geneset":"GO_METALLOENDOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METALLOENDOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."} {"geneset":"GO_PHOSPHATIDYLCHOLINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLCHOLINE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline."} {"geneset":"GO_TRANSLATION_ELONGATION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATION_ELONGATION_FACTOR_ACTIVITY","description":"Functions in chain elongation during polypeptide synthesis at the ribosome."} {"geneset":"GO_MONOSACCHARIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOSACCHARIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a monosaccharide from one side of a membrane to the other."} {"geneset":"GO_HYDROLASE_ACTIVITY_ACTING_ON_ESTER_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_ACTING_ON_ESTER_BONDS","description":"Catalysis of the hydrolysis of any ester bond."} {"geneset":"GO_CAMP_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CAMP_BINDING","description":"Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate)."} {"geneset":"GO_GLYCOSAMINOGLYCAN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOSAMINOGLYCAN_BINDING","description":"Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues."} {"geneset":"GO_VITAMIN_D_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VITAMIN_D_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes."} {"geneset":"GO_DAMAGED_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DAMAGED_DNA_BINDING","description":"Interacting selectively and non-covalently with damaged DNA."} {"geneset":"GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVATOR_ACTIVITY","description":"Binds to and increases the activity of a protein serine/threonine kinase."} {"geneset":"GO_PHOSPHOLIPID_TRANSLOCATING_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_TRANSLOCATING_ATPASE_ACTIVITY","description":"Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP."} {"geneset":"GO_ALCOHOL_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALCOHOL_BINDING","description":"Interacting selectively and non-covalently with an alcohol, any of a class of alkyl compounds containing a hydroxyl group."} {"geneset":"GO_L_ASCORBIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_L_ASCORBIC_ACID_BINDING","description":"Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species."} {"geneset":"GO_DIPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of a dipeptide."} {"geneset":"GO_GLUTAMATE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMATE_RECEPTOR_ACTIVITY","description":"Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."} {"geneset":"GO_GAMMA_TUBULIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GAMMA_TUBULIN_BINDING","description":"Interacting selectively and non-covalently with the microtubule constituent protein gamma-tubulin."} {"geneset":"GO_PEPTIDASE_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDASE_ACTIVATOR_ACTIVITY","description":"Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds."} {"geneset":"GO_POLY_PURINE_TRACT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLY_PURINE_TRACT_BINDING","description":"Interacting selectively and non-covalently with any stretch of purines (adenine or guanine) in an RNA molecule."} {"geneset":"GO_INTRONIC_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRONIC_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING","description":"Interacting selectively and non-covalently with an intronic DNA region that regulates the transcription of the transcript it is contained within."} {"geneset":"GO_HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES","description":"Catalysis of the hydrolysis of any acid anhydride."} {"geneset":"GO_STEROL_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROL_BINDING","description":"Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol."} {"geneset":"GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING","description":"Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_BINDING","description":"Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives."} {"geneset":"GO_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING","description":"Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types."} {"geneset":"GO_SH3_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SH3_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins."} {"geneset":"GO_LIGASE_ACTIVITY_FORMING_CARBON_SULFUR_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGASE_ACTIVITY_FORMING_CARBON_SULFUR_BONDS","description":"Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."} {"geneset":"GO_MANNOSE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MANNOSE_BINDING","description":"Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans."} {"geneset":"GO_RNA_POLYMERASE_II_REPRESSING_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_REPRESSING_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription."} {"geneset":"GO_CATION_SUGAR_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_SUGAR_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in)."} {"geneset":"GO_PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate."} {"geneset":"GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."} {"geneset":"GO_AMINOACYL_TRNA_EDITING_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINOACYL_TRNA_EDITING_ACTIVITY","description":"The hydrolysis of an incorrectly aminoacylated tRNA."} {"geneset":"GO_FOLIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOLIC_ACID_BINDING","description":"Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."} {"geneset":"GO_E_BOX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_E_BOX_BINDING","description":"Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues."} {"geneset":"GO_GLUCOSE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOSE_BINDING","description":"Interacting selectively and non-covalently with the D- or L-enantiomer of glucose."} {"geneset":"GO_NEUROTRANSMITTER_SODIUM_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTRANSMITTER_SODIUM_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in)."} {"geneset":"GO_NUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of ester linkages within nucleic acids."} {"geneset":"GO_DIPEPTIDYL_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIPEPTIDYL_PEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain."} {"geneset":"GO_TOXIC_SUBSTANCE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TOXIC_SUBSTANCE_BINDING","description":"Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems."} {"geneset":"GO_ESTRADIOL_17_BETA_DEHYDROGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ESTRADIOL_17_BETA_DEHYDROGENASE_ACTIVITY","description":"Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+."} {"geneset":"GO_GDP_DISSOCIATION_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GDP_DISSOCIATION_INHIBITOR_ACTIVITY","description":"Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding."} {"geneset":"GO_POLYSACCHARIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYSACCHARIDE_BINDING","description":"Interacting selectively and non-covalently with any polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."} {"geneset":"GO_SNAP_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SNAP_RECEPTOR_ACTIVITY","description":"Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion."} {"geneset":"GO_MICROTUBULE_SEVERING_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_SEVERING_ATPASE_ACTIVITY","description":"Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP."} {"geneset":"GO_RRNA_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule."} {"geneset":"GO_NON_MEMBRANE_SPANNING_PROTEIN_TYROSINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NON_MEMBRANE_SPANNING_PROTEIN_TYROSINE_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + a non-membrane spanning protein L-tyrosine = ADP + a non-membrane spanning protein L-tyrosine phosphate."} {"geneset":"GO_H4_HISTONE_ACETYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_H4_HISTONE_ACETYLTRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4."} {"geneset":"GO_HISTONE_DEMETHYLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_DEMETHYLASE_ACTIVITY","description":"Catalysis of the removal of a methyl group from a histone."} {"geneset":"GO_EXONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end."} {"geneset":"GO_MACROLIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROLIDE_BINDING","description":"Interacting selectively and non-covalently with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species."} {"geneset":"GO_INSULIN_LIKE_GROWTH_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INSULIN_LIKE_GROWTH_FACTOR_BINDING","description":"Interacting selectively and non-covalently with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it."} {"geneset":"GO_O_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_O_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule."} {"geneset":"GO_TROPOMYOSIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TROPOMYOSIN_BINDING","description":"Interacting selectively and non-covalently with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle."} {"geneset":"GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group."} {"geneset":"GO_LYSOZYME_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSOZYME_ACTIVITY","description":"Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins."} {"geneset":"GO_ANION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANION_CHANNEL_ACTIVITY","description":"Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient."} {"geneset":"GO_STRUCTURAL_CONSTITUENT_OF_NUCLEAR_PORE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRUCTURAL_CONSTITUENT_OF_NUCLEAR_PORE","description":"The action of a molecule that contributes to the structural integrity of the nuclear pore complex."} {"geneset":"GO_NUCLEOTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDASE_ACTIVITY","description":"Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate."} {"geneset":"GO_ION_ANTIPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ION_ANTIPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ion A(out) + ion B(in) = ion A(in) + ion B(out) where ion A and ion B are different types of ion."} {"geneset":"GO_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY","description":"Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3."} {"geneset":"GO_SIGNALING_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNALING_RECEPTOR_ACTIVITY","description":"Receiving a signal and transmitting the signal in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response."} {"geneset":"GO_SUGAR_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUGAR_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Catalysis of the transfer of a sugar from one side of the membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides."} {"geneset":"GO_INTERLEUKIN_1_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERLEUKIN_1_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the interleukin-1 receptor."} {"geneset":"GO_PROTEIN_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of proteins into, out of or within a cell, or between cells."} {"geneset":"GO_IMMUNOGLOBULIN_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IMMUNOGLOBULIN_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with one or more specific sites on an immunoglobulin receptor molecule."} {"geneset":"GO_RECEPTOR_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_ACTIVATOR_ACTIVITY","description":"The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased."} {"geneset":"GO_ALCOHOL_DEHYDROGENASE_NADP_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALCOHOL_DEHYDROGENASE_NADP_ACTIVITY","description":"Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+."} {"geneset":"GO_NEUROTRANSMITTER_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTRANSMITTER_RECEPTOR_ACTIVITY","description":"Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity."} {"geneset":"GO_DIACYLGLYCEROL_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIACYLGLYCEROL_BINDING","description":"Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty acids."} {"geneset":"GO_PHOSPHOLIPASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid."} {"geneset":"GO_ACTININ_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTININ_BINDING","description":"Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin."} {"geneset":"GO_PROTEIN_SERINE_THREONINE_KINASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SERINE_THREONINE_KINASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a protein serine/threonine kinase."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_SULFUR_GROUP_OF_DONORS_DISULFIDE_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_SULFUR_GROUP_OF_DONORS_DISULFIDE_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide."} {"geneset":"GO_TRANSCRIPTION_COFACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_COFACTOR_BINDING","description":"Interacting selectively and non-covalently with a transcription cofactor, any protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery."} {"geneset":"GO_HSP90_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HSP90_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size."} {"geneset":"GO_AMINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMINE_BINDING","description":"Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group."} {"geneset":"GO_DIOXYGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DIOXYGENASE_ACTIVITY","description":"Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products."} {"geneset":"GO_PHOSPHOTRANSFERASE_ACTIVITY_FOR_OTHER_SUBSTITUTED_PHOSPHATE_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOTRANSFERASE_ACTIVITY_FOR_OTHER_SUBSTITUTED_PHOSPHATE_GROUPS","description":"Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor)."} {"geneset":"GO_PALMITOYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PALMITOYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule."} {"geneset":"GO_NUCLEAR_LOCALIZATION_SEQUENCE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEAR_LOCALIZATION_SEQUENCE_BINDING","description":"Interacting selectively and non-covalently with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus."} {"geneset":"GO_RECEPTOR_AGONIST_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_AGONIST_ACTIVITY","description":"Interacts with receptors such that the proportion of receptors in the active form is increased."} {"geneset":"GO_PHOSPHATASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATASE_BINDING","description":"Interacting selectively and non-covalently with any phosphatase."} {"geneset":"GO_RNA_DIRECTED_DNA_POLYMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_DIRECTED_DNA_POLYMERASE_ACTIVITY","description":"Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time."} {"geneset":"GO_RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","description":"Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ras superfamily. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."} {"geneset":"GO_PROTEIN_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a methyl group (CH3-) to a protein."} {"geneset":"GO_LYSOPHOSPHOLIPID_ACYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSOPHOSPHOLIPID_ACYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid."} {"geneset":"GO_STRUCTURAL_CONSTITUENT_OF_MUSCLE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRUCTURAL_CONSTITUENT_OF_MUSCLE","description":"The action of a molecule that contributes to the structural integrity of a muscle fiber."} {"geneset":"GO_ENZYME_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENZYME_ACTIVATOR_ACTIVITY","description":"Binds to and increases the activity of an enzyme."} {"geneset":"GO_SH2_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SH2_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class."} {"geneset":"GO_CARBON_CARBON_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBON_CARBON_LYASE_ACTIVITY","description":"Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."} {"geneset":"GO_PROTEIN_COMPLEX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_COMPLEX_BINDING","description":"Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules)."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS","description":"Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)."} {"geneset":"GO_FATTY_ACID_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of fatty acids into, out of or within a cell, or between cells. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."} {"geneset":"GO_PROTEIN_TYROSINE_SERINE_THREONINE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TYROSINE_SERINE_THREONINE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate."} {"geneset":"GO_NUCLEOSIDE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate."} {"geneset":"GO_NUCLEIC_ACID_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEIC_ACID_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY","description":"Interacting selectively and non-covalently with a DNA or RNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."} {"geneset":"GO_FIBROBLAST_GROWTH_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FIBROBLAST_GROWTH_FACTOR_BINDING","description":"Interacting selectively and non-covalently with a fibroblast growth factor."} {"geneset":"GO_ADP_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADP_BINDING","description":"Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate."} {"geneset":"GO_BETA_1_3_GALACTOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_1_3_GALACTOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage."} {"geneset":"GO_CATION_TRANSPORTING_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_TRANSPORTING_ATPASE_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in)."} {"geneset":"GO_ATPASE_COUPLED_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_COUPLED_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Catalysis of the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate."} {"geneset":"GO_STEROL_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROL_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."} {"geneset":"GO_RNA_POLYMERASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_BINDING","description":"Interacting selectively and non-covalently with an RNA polymerase molecule or complex."} {"geneset":"GO_CARBOHYDRATE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_KINASE_ACTIVITY","description":"Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule."} {"geneset":"GO_BINDING_BRIDGING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BINDING_BRIDGING","description":"The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way."} {"geneset":"GO_THREONINE_TYPE_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THREONINE_TYPE_PEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile."} {"geneset":"GO_MONOOXYGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOOXYGENASE_ACTIVITY","description":"Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water."} {"geneset":"GO_ADENOSINE_DEAMINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADENOSINE_DEAMINASE_ACTIVITY","description":"Catalysis of the reaction: adenosine + H2O = inosine + NH3."} {"geneset":"GO_STRUCTURAL_CONSTITUENT_OF_RIBOSOME","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRUCTURAL_CONSTITUENT_OF_RIBOSOME","description":"The action of a molecule that contributes to the structural integrity of the ribosome."} {"geneset":"GO_14_3_3_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_14_3_3_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins."} {"geneset":"GO_COPPER_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COPPER_ION_BINDING","description":"Interacting selectively and non-covalently with copper (Cu) ions."} {"geneset":"GO_MISMATCHED_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MISMATCHED_DNA_BINDING","description":"Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatches."} {"geneset":"GO_HYDROLASE_ACTIVITY_ACTING_ON_GLYCOSYL_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_ACTING_ON_GLYCOSYL_BONDS","description":"Catalysis of the hydrolysis of any glycosyl bond."} {"geneset":"GO_RAB_GTPASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAB_GTPASE_BINDING","description":"Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases."} {"geneset":"GO_NAD_ADP_RIBOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NAD_ADP_RIBOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor."} {"geneset":"GO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","description":"Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."} {"geneset":"GO_TELOMERASE_RNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERASE_RNA_BINDING","description":"Interacting selectively and non-covalently with the telomerase RNA template."} {"geneset":"GO_BETA_TUBULIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_TUBULIN_BINDING","description":"Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin."} {"geneset":"GO_INTRAMOLECULAR_TRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRAMOLECULAR_TRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a functional group from one position to another within a single molecule."} {"geneset":"GO_SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme."} {"geneset":"GO_HELICASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HELICASE_ACTIVITY","description":"Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix."} {"geneset":"GO_RNA_POLYMERASE_CORE_ENZYME_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_CORE_ENZYME_BINDING","description":"Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme."} {"geneset":"GO_VOLTAGE_GATED_CHLORIDE_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_CHLORIDE_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."} {"geneset":"GO_PYRIDOXAL_PHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PYRIDOXAL_PHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6."} {"geneset":"GO_LIPASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid."} {"geneset":"GO_CHROMATIN_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_DNA_BINDING","description":"Interacting selectively and non-covalently with DNA that is assembled into chromatin."} {"geneset":"GO_ATPASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_BINDING","description":"Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP."} {"geneset":"GO_LAMIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAMIN_BINDING","description":"Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate."} {"geneset":"GO_CYCLIC_NUCLEOTIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIC_NUCLEOTIDE_BINDING","description":"Interacting selectively and non-covalently with a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."} {"geneset":"GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."} {"geneset":"GO_OLIGOPEPTIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OLIGOPEPTIDE_BINDING","description":"Interacting selectively and non-covalently with an oligopeptide."} {"geneset":"GO_CO_SMAD_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CO_SMAD_BINDING","description":"Interacting selectively and non-covalently with a common mediator SMAD signaling protein."} {"geneset":"GO_GROWTH_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GROWTH_FACTOR_ACTIVITY","description":"The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation."} {"geneset":"GO_INTRACELLULAR_CALCIUM_ACTIVATED_CHLORIDE_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_CALCIUM_ACTIVATED_CHLORIDE_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism."} {"geneset":"GO_G_PROTEIN_COUPLED_PHOTORECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_PHOTORECEPTOR_ACTIVITY","description":"Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."} {"geneset":"GO_ALDO_KETO_REDUCTASE_NADP_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALDO_KETO_REDUCTASE_NADP_ACTIVITY","description":"Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS_OTHER_THAN_AMINO_ACYL_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS_OTHER_THAN_AMINO_ACYL_GROUPS","description":"Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor)."} {"geneset":"GO_MOLECULAR_FUNCTION_REGULATOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MOLECULAR_FUNCTION_REGULATOR","description":"A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators."} {"geneset":"GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS","description":"Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process."} {"geneset":"GO_FIBRONECTIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FIBRONECTIN_BINDING","description":"Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids."} {"geneset":"GO_POTASSIUM_TRANSPORTING_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POTASSIUM_TRANSPORTING_ATPASE_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in)."} {"geneset":"GO_MICROTUBULE_MOTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_MOTOR_ACTIVITY","description":"Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_OXIDIZING_METAL_IONS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_OXIDIZING_METAL_IONS","description":"Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered."} {"geneset":"GO_ALPHA_TUBULIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALPHA_TUBULIN_BINDING","description":"Interacting selectively and non-covalently with the microtubule constituent protein alpha-tubulin."} {"geneset":"GO_EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular excitatory ligand has been bound by the channel complex or one of its constituent parts. Excitatory ligands, such as acetylcholine or glutamate, open cation-selective channels."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_OXIDIZING_METAL_IONS_NAD_OR_NADP_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_OXIDIZING_METAL_IONS_NAD_OR_NADP_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or NADP+ acts as an electron acceptor."} {"geneset":"GO_ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES","description":"Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance."} {"geneset":"GO_TRANSITION_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSITION_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver."} {"geneset":"GO_DOUBLE_STRANDED_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOUBLE_STRANDED_DNA_BINDING","description":"Interacting selectively and non-covalently with double-stranded DNA."} {"geneset":"GO_TRANSITION_METAL_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSITION_METAL_ION_BINDING","description":"Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver."} {"geneset":"GO_TELOMERIC_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TELOMERIC_DNA_BINDING","description":"Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end."} {"geneset":"GO_MODIFIED_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODIFIED_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of modified amino acids from one side of a membrane to the other."} {"geneset":"GO_SCAFFOLD_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SCAFFOLD_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes."} {"geneset":"GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with an RNA polymerase II activating transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription."} {"geneset":"GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a low-density lipoprotein receptor."} {"geneset":"GO_PHOSPHATIDYLSERINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLSERINE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine."} {"geneset":"GO_GLYCOLIPID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOLIPID_BINDING","description":"Interacting selectively and non-covalently with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate."} {"geneset":"GO_RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","description":"Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."} {"geneset":"GO_CALMODULIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALMODULIN_BINDING","description":"Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states."} {"geneset":"GO_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING","description":"Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase II basal transcription machinery."} {"geneset":"GO_MAP_KINASE_KINASE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAP_KINASE_KINASE_KINASE_ACTIVITY","description":"Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases."} {"geneset":"GO_MHC_CLASS_II_PROTEIN_COMPLEX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MHC_CLASS_II_PROTEIN_COMPLEX_BINDING","description":"Interacting selectively and non-covalently with the class II major histocompatibility complex."} {"geneset":"GO_PHOSPHOTYROSINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOTYROSINE_BINDING","description":"Interacting selectively and non-covalently with a phosphorylated tyrosine residue within a protein."} {"geneset":"GO_NUCLEOSIDE_TRIPHOSPHATASE_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSIDE_TRIPHOSPHATASE_REGULATOR_ACTIVITY","description":"Modulates the rate of NTP hydrolysis by a NTPase."} {"geneset":"GO_LIGAND_GATED_CALCIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGAND_GATED_CALCIUM_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_RIBOSOMAL_SMALL_SUBUNIT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOMAL_SMALL_SUBUNIT_BINDING","description":"Interacting selectively and non-covalently with any part of the small ribosomal subunit."} {"geneset":"GO_OMEGA_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OMEGA_PEPTIDASE_ACTIVITY","description":"Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by isopeptide bonds (peptide linkages other than those of alpha-carboxyl to alpha-amino groups)."} {"geneset":"GO_PHOSPHATIDYLCHOLINE_1_ACYLHYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLCHOLINE_1_ACYLHYDROLASE_ACTIVITY","description":"Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate."} {"geneset":"GO_ELECTRON_CARRIER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ELECTRON_CARRIER_ACTIVITY","description":"Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient."} {"geneset":"GO_HMG_BOX_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HMG_BOX_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin."} {"geneset":"GO_CHANNEL_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHANNEL_INHIBITOR_ACTIVITY","description":"Stops, prevents, or reduces the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel."} {"geneset":"GO_SUMO_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUMO_BINDING","description":"Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO."} {"geneset":"GO_PALMITOYL_COA_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PALMITOYL_COA_HYDROLASE_ACTIVITY","description":"Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate."} {"geneset":"GO_MANNOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MANNOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid."} {"geneset":"GO_RECEPTOR_SERINE_THREONINE_KINASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_SERINE_THREONINE_KINASE_BINDING","description":"Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity."} {"geneset":"GO_RETINAL_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINAL_BINDING","description":"Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS","description":"Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor)."} {"geneset":"GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the transforming growth factor beta receptor."} {"geneset":"GO_WW_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WW_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions."} {"geneset":"GO_PEPTIDE_N_ACETYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_N_ACETYLTRANSFERASE_ACTIVITY","description":"Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide."} {"geneset":"GO_GLUCOCORTICOID_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOCORTICOID_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a glucocorticoid receptor."} {"geneset":"GO_LIGASE_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGASE_REGULATOR_ACTIVITY","description":"Modulates the activity of a ligase."} {"geneset":"GO_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction."} {"geneset":"GO_CAMP_RESPONSE_ELEMENT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CAMP_RESPONSE_ELEMENT_BINDING","description":"Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP."} {"geneset":"GO_PROTEIN_DISULFIDE_OXIDOREDUCTASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DISULFIDE_OXIDOREDUCTASE_ACTIVITY","description":"Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_BISPHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_BISPHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol bisphosphate."} {"geneset":"GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of calcium (Ca) ions from one side of a membrane to the other."} {"geneset":"GO_INTERMEDIATE_FILAMENT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERMEDIATE_FILAMENT_BINDING","description":"Interacting selectively and non-covalently with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space."} {"geneset":"GO_AMIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMIDE_BINDING","description":"Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group."} {"geneset":"GO_LIPOPOLYSACCHARIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOPOLYSACCHARIDE_BINDING","description":"Interacting selectively and non-covalently with lipopolysaccharide."} {"geneset":"GO_LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein."} {"geneset":"GO_POLYPEPTIDE_N_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYPEPTIDE_N_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis."} {"geneset":"GO_MODIFIED_AMINO_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MODIFIED_AMINO_ACID_BINDING","description":"Interacting selectively and non-covalently with a modified amino acid."} {"geneset":"GO_ION_CHANNEL_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ION_CHANNEL_BINDING","description":"Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient."} {"geneset":"GO_FILAMIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FILAMIN_BINDING","description":"Interacting selectively and non-covalently with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain."} {"geneset":"GO_PROTEOGLYCAN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEOGLYCAN_BINDING","description":"Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans."} {"geneset":"GO_SUMO_TRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUMO_TRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages."} {"geneset":"GO_MYOSIN_HEAVY_CHAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOSIN_HEAVY_CHAIN_BINDING","description":"Interacting selectively and non-covalently with a heavy chain of a myosin complex."} {"geneset":"GO_LRR_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LRR_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with a LRR domain (leucine rich repeats) of a protein."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_AMINO_ACYL_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_AMINO_ACYL_GROUPS","description":"Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)."} {"geneset":"GO_INTEGRIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTEGRIN_BINDING","description":"Interacting selectively and non-covalently with an integrin."} {"geneset":"GO_ALCOHOL_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALCOHOL_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of an alcohol from one side of the membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group."} {"geneset":"GO_CALMODULIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALMODULIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","description":"Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin."} {"geneset":"GO_MICROFILAMENT_MOTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROFILAMENT_MOTOR_ACTIVITY","description":"Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)."} {"geneset":"GO_THIOL_DEPENDENT_UBIQUITIN_SPECIFIC_PROTEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THIOL_DEPENDENT_UBIQUITIN_SPECIFIC_PROTEASE_ACTIVITY","description":"Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein."} {"geneset":"GO_FERROUS_IRON_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FERROUS_IRON_BINDING","description":"Interacting selectively and non-covalently with ferrous iron, Fe(II)."} {"geneset":"GO_ACETYLCHOLINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACETYLCHOLINE_BINDING","description":"Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions."} {"geneset":"GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING","description":"Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II."} {"geneset":"GO_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."} {"geneset":"GO_NAD_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NAD_BINDING","description":"Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH."} {"geneset":"GO_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a negatively charged ion from one side of a membrane to the other."} {"geneset":"GO_CHAPERONE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHAPERONE_BINDING","description":"Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport."} {"geneset":"GO_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate."} {"geneset":"GO_IDENTICAL_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IDENTICAL_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with an identical protein or proteins."} {"geneset":"GO_GALACTOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GALACTOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid."} {"geneset":"GO_PHOSPHOTRANSFERASE_ACTIVITY_PHOSPHATE_GROUP_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOTRANSFERASE_ACTIVITY_PHOSPHATE_GROUP_AS_ACCEPTOR","description":"Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor)."} {"geneset":"GO_ALKALI_METAL_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALKALI_METAL_ION_BINDING","description":"Interacting selectively and non-covalently with any alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen."} {"geneset":"GO_RIBONUCLEOPROTEIN_COMPLEX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOPROTEIN_COMPLEX_BINDING","description":"Interacting selectively and non-covalently with any complex of RNA and protein."} {"geneset":"GO_DNA_APURINIC_OR_APYRIMIDINIC_SITE_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_APURINIC_OR_APYRIMIDINIC_SITE_LYASE_ACTIVITY","description":"Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate."} {"geneset":"GO_NEUROPILIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROPILIN_BINDING","description":"Interacting selectively and non-covalently with a member of the neuropilin family."} {"geneset":"GO_PEPTIDE_ANTIGEN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_ANTIGEN_BINDING","description":"Interacting selectively and non-covalently with an antigen peptide."} {"geneset":"GO_DYNEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DYNEIN_BINDING","description":"Interacting selectively and non-covalently with dynein, the multisubunit protein complex that is associated with microtubules."} {"geneset":"GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."} {"geneset":"GO_RAGE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAGE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products."} {"geneset":"GO_TRANSLATION_FACTOR_ACTIVITY_RNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATION_FACTOR_ACTIVITY_RNA_BINDING","description":"Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome."} {"geneset":"GO_LOW_DENSITY_LIPOPROTEIN_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LOW_DENSITY_LIPOPROTEIN_RECEPTOR_ACTIVITY","description":"Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein into the cell via endocytosis."} {"geneset":"GO_CGMP_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CGMP_BINDING","description":"Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate)."} {"geneset":"GO_DRUG_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DRUG_BINDING","description":"Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease."} {"geneset":"GO_SPECTRIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPECTRIN_BINDING","description":"Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers."} {"geneset":"GO_O_ACYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_O_ACYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_NITROGENOUS_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_NITROGENOUS_GROUPS","description":"Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor)."} {"geneset":"GO_TRANSLATION_INITIATION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATION_INITIATION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation."} {"geneset":"GO_BILE_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BILE_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of bile acid from one side of the membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine."} {"geneset":"GO_PEPTIDASE_ACTIVATOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDASE_ACTIVATOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS","description":"Increases the activity of a peptidase that is involved in the apoptotic process."} {"geneset":"GO_METAL_CLUSTER_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METAL_CLUSTER_BINDING","description":"Interacting selectively and non-covalently with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters."} {"geneset":"GO_ENZYME_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENZYME_INHIBITOR_ACTIVITY","description":"Binds to and stops, prevents or reduces the activity of an enzyme."} {"geneset":"GO_OXYGEN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXYGEN_BINDING","description":"Interacting selectively and non-covalently with oxygen (O2)."} {"geneset":"GO_ENDODEOXYRIBONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDODEOXYRIBONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."} {"geneset":"GO_CARBON_NITROGEN_LIGASE_ACTIVITY_WITH_GLUTAMINE_AS_AMIDO_N_DONOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBON_NITROGEN_LIGASE_ACTIVITY_WITH_GLUTAMINE_AS_AMIDO_N_DONOR","description":"Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP."} {"geneset":"GO_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other."} {"geneset":"GO_LONG_CHAIN_FATTY_ACID_COA_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LONG_CHAIN_FATTY_ACID_COA_LIGASE_ACTIVITY","description":"Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22."} {"geneset":"GO_DEATH_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEATH_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD)."} {"geneset":"GO_SUPEROXIDE_GENERATING_NADPH_OXIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SUPEROXIDE_GENERATING_NADPH_OXIDASE_ACTIVITY","description":"Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-."} {"geneset":"GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY_TRANSPOSING_S_S_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY_TRANSPOSING_S_S_BONDS","description":"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears."} {"geneset":"GO_RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","description":"Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."} {"geneset":"GO_BICARBONATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BICARBONATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-."} {"geneset":"GO_HORMONE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HORMONE_BINDING","description":"Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone."} {"geneset":"GO_INOSITOL_PHOSPHATE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_PHOSPHATE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate."} {"geneset":"GO_3_5_DNA_HELICASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_3_5_DNA_HELICASE_ACTIVITY","description":"Catalysis of the unwinding of the DNA helix in the direction 3' to 5'."} {"geneset":"GO_FOUR_WAY_JUNCTION_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FOUR_WAY_JUNCTION_DNA_BINDING","description":"Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices."} {"geneset":"GO_ISOPRENOID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ISOPRENOID_BINDING","description":"Interacting selectively and non-covalently with any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."} {"geneset":"GO_PROTEIN_KINASE_A_CATALYTIC_SUBUNIT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_A_CATALYTIC_SUBUNIT_BINDING","description":"Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A."} {"geneset":"GO_INOSITOL_TRISPHOSPHATE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_TRISPHOSPHATE_KINASE_ACTIVITY","description":"Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP."} {"geneset":"GO_MHC_CLASS_I_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MHC_CLASS_I_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation."} {"geneset":"GO_ORGANIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ACID_BINDING","description":"Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage."} {"geneset":"GO_GABA_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GABA_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor."} {"geneset":"GO_CARBOXYLIC_ESTER_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOXYLIC_ESTER_HYDROLASE_ACTIVITY","description":"Catalysis of the hydrolysis of a carboxylic ester bond."} {"geneset":"GO_CARBON_SULFUR_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBON_SULFUR_LYASE_ACTIVITY","description":"Catalysis of the elimination of hydrogen sulfide or substituted H2S."} {"geneset":"GO_CARGO_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARGO_RECEPTOR_ACTIVITY","description":"Combining selectively with an extracellular substance and delivering the substance into the cell via endocytosis."} {"geneset":"GO_LIPASE_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPASE_ACTIVATOR_ACTIVITY","description":"Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid."} {"geneset":"GO_SOLUTE_CATION_ANTIPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOLUTE_CATION_ANTIPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out)."} {"geneset":"GO_GLUCURONOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCURONOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside."} {"geneset":"GO_ANNEALING_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANNEALING_ACTIVITY","description":"A nucleic acid binding activity that brings together complementary sequences of nucleic acids so that they pair by hydrogen bonds to form a double-stranded polynucleotide."} {"geneset":"GO_ION_GATED_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ION_GATED_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus."} {"geneset":"GO_HYDROGEN_EXPORTING_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROGEN_EXPORTING_ATPASE_ACTIVITY","description":"Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -ADP + phosphate + H+(out)."} {"geneset":"GO_MAP_KINASE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAP_KINASE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate."} {"geneset":"GO_HEPARAN_SULFATE_PROTEOGLYCAN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEPARAN_SULFATE_PROTEOGLYCAN_BINDING","description":"Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit."} {"geneset":"GO_ORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage."} {"geneset":"GO_WIDE_PORE_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WIDE_PORE_CHANNEL_ACTIVITY","description":"Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts."} {"geneset":"GO_DEOXYRIBONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEOXYRIBONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid."} {"geneset":"GO_RRNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RRNA_BINDING","description":"Interacting selectively and non-covalently with ribosomal RNA."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_SINGLE_DONORS_WITH_INCORPORATION_OF_MOLECULAR_OXYGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_SINGLE_DONORS_WITH_INCORPORATION_OF_MOLECULAR_OXYGEN","description":"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor."} {"geneset":"GO_ORGANIC_ACID_SODIUM_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_ACID_SODIUM_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in)."} {"geneset":"GO_CARBOHYDRATE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBOHYDRATE_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of carbohydrate into, out of or within a cell, or between cells."} {"geneset":"GO_VITAMIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VITAMIN_BINDING","description":"Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."} {"geneset":"GO_RAL_GTPASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAL_GTPASE_BINDING","description":"Interacting selectively and non-covalently with Ral protein, any member of the Ral subfamily of the Ras superfamily of monomeric GTPases."} {"geneset":"GO_CHEMOKINE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMOKINE_ACTIVITY","description":"The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria."} {"geneset":"GO_UDP_GLYCOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UDP_GLYCOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule."} {"geneset":"GO_GLUTATHIONE_TRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTATHIONE_TRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H_OXYGEN_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H_OXYGEN_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule."} {"geneset":"GO_SULFOTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFOTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate."} {"geneset":"GO_WNT_ACTIVATED_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WNT_ACTIVATED_RECEPTOR_ACTIVITY","description":"Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_PHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_PHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position."} {"geneset":"GO_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYASE_ACTIVITY","description":"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring."} {"geneset":"GO_CHOLESTEROL_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHOLESTEROL_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of cholesterol into, out of or within a cell, or between cells. Cholesterol is the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."} {"geneset":"GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING","description":"Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."} {"geneset":"GO_SINGLE_STRANDED_DNA_DEPENDENT_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_STRANDED_DNA_DEPENDENT_ATPASE_ACTIVITY","description":"Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction."} {"geneset":"GO_N_ACYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_N_ACYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule."} {"geneset":"GO_PROTEIN_PHOSPHATASE_1_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_PHOSPHATASE_1_BINDING","description":"Interacting selectively and non-covalently with the enzyme protein phosphatase 1."} {"geneset":"GO_CHEMOATTRACTANT_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMOATTRACTANT_ACTIVITY","description":"Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal."} {"geneset":"GO_CORECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORECEPTOR_ACTIVITY","description":"Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity."} {"geneset":"GO_QUATERNARY_AMMONIUM_GROUP_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_QUATERNARY_AMMONIUM_GROUP_BINDING","description":"Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups."} {"geneset":"GO_VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."} {"geneset":"GO_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY","description":"Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK)."} {"geneset":"GO_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a substance from one side of a membrane to the other."} {"geneset":"GO_CHEMOKINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMOKINE_BINDING","description":"Interacting selectively and non-covalently with a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria."} {"geneset":"GO_PEPTIDE_HORMONE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_HORMONE_BINDING","description":"Interacting selectively and non-covalently with any peptide with hormonal activity in animals."} {"geneset":"GO_KINESIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINESIN_BINDING","description":"Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring."} {"geneset":"GO_UBIQUITIN_LIKE_PROTEIN_CONJUGATING_ENZYME_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_LIKE_PROTEIN_CONJUGATING_ENZYME_BINDING","description":"Interacting selectively and non-covalently with a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme."} {"geneset":"GO_STEROID_HORMONE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_HORMONE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a steroid hormone receptor."} {"geneset":"GO_BITTER_TASTE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BITTER_TASTE_RECEPTOR_ACTIVITY","description":"Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste."} {"geneset":"GO_PROTEIN_KINASE_C_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_KINASE_C_ACTIVITY","description":"Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol."} {"geneset":"GO_AU_RICH_ELEMENT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AU_RICH_ELEMENT_BINDING","description":"Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases."} {"geneset":"GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_BINDING","description":"Interacting selectively and non-covalently with a ubiquitin-like protein ligase, such as ubiquitin-ligase."} {"geneset":"GO_LIPOPROTEIN_PARTICLE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPOPROTEIN_PARTICLE_RECEPTOR_ACTIVITY","description":"Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids."} {"geneset":"GO_RNA_HELICASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_HELICASE_ACTIVITY","description":"Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a RNA helix."} {"geneset":"GO_CYCLIN_DEPENDENT_PROTEIN_SERINE_THREONINE_KINASE_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYCLIN_DEPENDENT_PROTEIN_SERINE_THREONINE_KINASE_REGULATOR_ACTIVITY","description":"Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins."} {"geneset":"GO_CCR_CHEMOKINE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CCR_CHEMOKINE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a CCR chemokine receptor."} {"geneset":"GO_GABA_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GABA_RECEPTOR_ACTIVITY","description":"Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms."} {"geneset":"GO_DNA_DEPENDENT_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DEPENDENT_ATPASE_ACTIVITY","description":"Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction."} {"geneset":"GO_METALLOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METALLOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."} {"geneset":"GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_ACTIVITY","description":"Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP."} {"geneset":"GO_GUANYL_NUCLEOTIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GUANYL_NUCLEOTIDE_BINDING","description":"Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_KINASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_KINASE_BINDING","description":"Interacting selectively and non-covalently with a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring."} {"geneset":"GO_ENDONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks."} {"geneset":"GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING","description":"Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter."} {"geneset":"GO_ANION_ANION_ANTIPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANION_ANION_ANTIPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out)."} {"geneset":"GO_TASTE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TASTE_RECEPTOR_ACTIVITY","description":"Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste."} {"geneset":"GO_ORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage."} {"geneset":"GO_WATER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_WATER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of water (H2O) from one side of a membrane to the other."} {"geneset":"GO_ACTIVIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVIN_BINDING","description":"Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS","description":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."} {"geneset":"GO_BETA_AMYLOID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BETA_AMYLOID_BINDING","description":"Interacting selectively and non-covalently with beta-amyloid peptide/protein and/or its precursor."} {"geneset":"GO_HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS","description":"Catalysis of the hydrolysis of any N-glycosyl bond."} {"geneset":"GO_PROTEIN_HORMONE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_HORMONE_RECEPTOR_ACTIVITY","description":"Combining with a protein hormone to initiate a change in cell activity."} {"geneset":"GO_CHEMOKINE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMOKINE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with any chemokine receptor."} {"geneset":"GO_PROLINE_RICH_REGION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROLINE_RICH_REGION_BINDING","description":"Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein."} {"geneset":"GO_VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN","description":"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor."} {"geneset":"GO_TRANSCRIPTION_FACTOR_ACTIVITY_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_ACTIVITY_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."} {"geneset":"GO_INTRAMOLECULAR_TRANSFERASE_ACTIVITY_PHOSPHOTRANSFERASES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRAMOLECULAR_TRANSFERASE_ACTIVITY_PHOSPHOTRANSFERASES","description":"Catalysis of the transfer of a phosphate group from one position to another within a single molecule."} {"geneset":"GO_SINGLE_STRANDED_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SINGLE_STRANDED_DNA_BINDING","description":"Interacting selectively and non-covalently with single-stranded DNA."} {"geneset":"GO_TYPE_I_INTERFERON_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TYPE_I_INTERFERON_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2)."} {"geneset":"GO_RIBONUCLEOTIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEOTIDE_BINDING","description":"Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety."} {"geneset":"GO_TRANSCRIPTION_COACTIVATOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_COACTIVATOR_BINDING","description":"Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery."} {"geneset":"GO_RETINOIC_ACID_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINOIC_ACID_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate."} {"geneset":"GO_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription."} {"geneset":"GO_NEUREXIN_FAMILY_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUREXIN_FAMILY_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals."} {"geneset":"GO_MICROTUBULE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_BINDING","description":"Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers."} {"geneset":"GO_TUBULIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TUBULIN_BINDING","description":"Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules."} {"geneset":"GO_ORGANOPHOSPHATE_ESTER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ORGANOPHOSPHATE_ESTER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds."} {"geneset":"GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_PHOSPHATASE_ACTIVITY","description":"Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate."} {"geneset":"GO_NADP_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NADP_BINDING","description":"Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH."} {"geneset":"GO_S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate."} {"geneset":"GO_KINASE_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_KINASE_ACTIVATOR_ACTIVITY","description":"Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule."} {"geneset":"GO_HISTONE_LYSINE_N_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_LYSINE_N_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives."} {"geneset":"GO_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the insulin-like growth factor receptor."} {"geneset":"GO_MOTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MOTOR_ACTIVITY","description":"Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate."} {"geneset":"GO_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription."} {"geneset":"GO_TRNA_SPECIFIC_RIBONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_SPECIFIC_RIBONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules."} {"geneset":"GO_SOLUTE_CATION_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOLUTE_CATION_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in)."} {"geneset":"GO_UBIQUITIN_SPECIFIC_PROTEASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_SPECIFIC_PROTEASE_BINDING","description":"Interacting selectively and non-covalently with a ubiquitin-specific protease."} {"geneset":"GO_PHOSPHOLIPID_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester."} {"geneset":"GO_RETINOID_X_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINOID_X_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a retinoid X receptor."} {"geneset":"GO_MONOCARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOCARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of monocarboxylic acids from one side of the membrane to the other. A monocarboxylic acid is an organic acid with one COOH group."} {"geneset":"GO_ANION_TRANSMEMBRANE_TRANSPORTING_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANION_TRANSMEMBRANE_TRANSPORTING_ATPASE_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + anion(out) = ADP + phosphate + anion(in)."} {"geneset":"GO_POTASSIUM_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POTASSIUM_ION_BINDING","description":"Interacting selectively and non-covalently with potassium (K+) ions."} {"geneset":"GO_BASAL_TRANSCRIPTION_MACHINERY_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BASAL_TRANSCRIPTION_MACHINERY_BINDING","description":"Interacting selectively and non-covalently with the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase."} {"geneset":"GO_INTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGASE_ACTIVITY_FORMING_CARBON_NITROGEN_BONDS","description":"Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."} {"geneset":"GO_1_PHOSPHATIDYLINOSITOL_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_1_PHOSPHATIDYLINOSITOL_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PEROXIDE_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PEROXIDE_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor."} {"geneset":"GO_GROWTH_FACTOR_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GROWTH_FACTOR_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a growth factor receptor."} {"geneset":"GO_PHOSPHOLIPASE_A2_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPASE_A2_ACTIVITY","description":"Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate."} {"geneset":"GO_TITIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TITIN_BINDING","description":"Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively."} {"geneset":"GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other."} {"geneset":"GO_GTPASE_ACTIVATING_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GTPASE_ACTIVATING_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with a GTPase activating protein."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS_OXYGEN_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS_OXYGEN_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule."} {"geneset":"GO_LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_TRANSCRIPTION_COACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_TRANSCRIPTION_COACTIVATOR_ACTIVITY","description":"The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself."} {"geneset":"GO_HSP70_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HSP70_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size."} {"geneset":"GO_SNRNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SNRNA_BINDING","description":"Interacting selectively and non-covalently with a small nuclear RNA (snRNA)."} {"geneset":"GO_ENZYME_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENZYME_REGULATOR_ACTIVITY","description":"Binds to and modulates the activity of an enzyme."} {"geneset":"GO_ARF_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARF_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","description":"Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."} {"geneset":"GO_CARBONATE_DEHYDRATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBONATE_DEHYDRATASE_ACTIVITY","description":"Catalysis of the reaction: H2CO3 = CO2 + H2O."} {"geneset":"GO_RECEPTOR_SIGNALING_COMPLEX_SCAFFOLD_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_SIGNALING_COMPLEX_SCAFFOLD_ACTIVITY","description":"Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex."} {"geneset":"GO_GLYCOPROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLYCOPROTEIN_BINDING","description":"Interacting selectively and non-covalently with a glycoprotein, a protein that contains covalently bound glycose (monosaccharide) residues. These also include proteoglycans."} {"geneset":"GO_MYOSIN_V_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOSIN_V_BINDING","description":"Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport."} {"geneset":"GO_EXOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both."} {"geneset":"GO_NUCLEOTIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other."} {"geneset":"GO_FUCOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FUCOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid."} {"geneset":"GO_SOLUTE_PROTON_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOLUTE_PROTON_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in)."} {"geneset":"GO_PLATELET_DERIVED_GROWTH_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_DERIVED_GROWTH_FACTOR_BINDING","description":"Interacting selectively and non-covalently with platelet-derived growth factor."} {"geneset":"GO_PHOSPHOTRANSFERASE_ACTIVITY_NITROGENOUS_GROUP_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOTRANSFERASE_ACTIVITY_NITROGENOUS_GROUP_AS_ACCEPTOR","description":"Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor)."} {"geneset":"GO_SNARE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SNARE_BINDING","description":"Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein."} {"geneset":"GO_GTP_RHO_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GTP_RHO_BINDING","description":"Interacting selectively and non-covalently with the GTP-bound form of the Rho protein."} {"geneset":"GO_DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow."} {"geneset":"GO_NAD_DEPENDENT_PROTEIN_DEACETYLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NAD_DEPENDENT_PROTEIN_DEACETYLASE_ACTIVITY","description":"Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD."} {"geneset":"GO_PHOSPHATIDIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDIC_ACID_BINDING","description":"Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids."} {"geneset":"GO_DICARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DICARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of dicarboxylic acids from one side of the membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups."} {"geneset":"GO_TRANSLATION_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATION_REGULATOR_ACTIVITY","description":"Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome."} {"geneset":"GO_ACETYLGLUCOSAMINYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACETYLGLUCOSAMINYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar."} {"geneset":"GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY_TRANSPOSING_C_C_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY_TRANSPOSING_C_C_BONDS","description":"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears."} {"geneset":"GO_NF_KAPPAB_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NF_KAPPAB_BINDING","description":"Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters."} {"geneset":"GO_SODIUM_INDEPENDENT_ORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_INDEPENDENT_ORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Catalysis of the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner."} {"geneset":"GO_BIOACTIVE_LIPID_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_BIOACTIVE_LIPID_RECEPTOR_ACTIVITY","description":"Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes."} {"geneset":"GO_STORE_OPERATED_CALCIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STORE_OPERATED_CALCIUM_CHANNEL_ACTIVITY","description":"A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores."} {"geneset":"GO_CALCIUM_DEPENDENT_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_DEPENDENT_PROTEIN_KINASE_ACTIVITY","description":"Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the presence of calcium."} {"geneset":"GO_MACROMOLECULE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMOLECULE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a macromolecule from one side of the membrane to the other."} {"geneset":"GO_PEPTIDASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds."} {"geneset":"GO_RAC_GTPASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAC_GTPASE_BINDING","description":"Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases."} {"geneset":"GO_SULFURIC_ESTER_HYDROLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SULFURIC_ESTER_HYDROLASE_ACTIVITY","description":"Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2."} {"geneset":"GO_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Chemiosmotic sources of energy include uniport, symport or antiport."} {"geneset":"GO_PEPTIDOGLYCAN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDOGLYCAN_BINDING","description":"Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls."} {"geneset":"GO_DRUG_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DRUG_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of a drug into, out of or within a cell, or between cells. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease."} {"geneset":"GO_HYALURONIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYALURONIC_ACID_BINDING","description":"Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine."} {"geneset":"GO_ENZYME_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENZYME_BINDING","description":"Interacting selectively and non-covalently with any enzyme."} {"geneset":"GO_TRANSLATION_REPRESSOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATION_REPRESSOR_ACTIVITY","description":"Antagonizes ribosome-mediated translation of mRNA into a polypeptide."} {"geneset":"GO_DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY","description":"Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group."} {"geneset":"GO_COFACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COFACTOR_BINDING","description":"Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate."} {"geneset":"GO_RNA_POLYMERASE_II_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription."} {"geneset":"GO_RNA_POLYMERASE_II_TRANSCRIPTION_COACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_TRANSCRIPTION_COACTIVATOR_ACTIVITY","description":"Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery."} {"geneset":"GO_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma."} {"geneset":"GO_K63_LINKED_POLYUBIQUITIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_K63_LINKED_POLYUBIQUITIN_BINDING","description":"Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_CH_OH_GROUP_OF_DONORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_CH_OH_GROUP_OF_DONORS","description":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."} {"geneset":"GO_CULLIN_FAMILY_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CULLIN_FAMILY_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with any member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3)."} {"geneset":"GO_PROTEIN_TYROSINE_KINASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TYROSINE_KINASE_BINDING","description":"Interacting selectively and non-covalently with protein tyrosine kinase."} {"geneset":"GO_INSULIN_RECEPTOR_SUBSTRATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INSULIN_RECEPTOR_SUBSTRATE_BINDING","description":"Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex."} {"geneset":"GO_MONOVALENT_CATION_PROTON_ANTIPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOVALENT_CATION_PROTON_ANTIPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out)."} {"geneset":"GO_ZINC_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ZINC_ION_BINDING","description":"Interacting selectively and non-covalently with zinc (Zn) ions."} {"geneset":"GO_TETRAPYRROLE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TETRAPYRROLE_BINDING","description":"Interacting selectively and non-covalently with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position."} {"geneset":"GO_3_5_EXONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_3_5_EXONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end."} {"geneset":"GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_KINASE_KINASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_KINASE_KINASE_BINDING","description":"Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase."} {"geneset":"GO_PDZ_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PDZ_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins."} {"geneset":"GO_POLY_A_RNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLY_A_RNA_BINDING","description":"Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases."} {"geneset":"GO_POTASSIUM_CHANNEL_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POTASSIUM_CHANNEL_REGULATOR_ACTIVITY","description":"Modulates the activity of a potassium channel."} {"geneset":"GO_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_G_PROTEIN_COUPLED_AMINE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_AMINE_RECEPTOR_ACTIVITY","description":"Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."} {"geneset":"GO_CXCR_CHEMOKINE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CXCR_CHEMOKINE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a chemokine receptor in the CXCR family."} {"geneset":"GO_IRON_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IRON_ION_BINDING","description":"Interacting selectively and non-covalently with iron (Fe) ions."} {"geneset":"GO_STEROID_HYDROXYLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STEROID_HYDROXYLASE_ACTIVITY","description":"Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2."} {"geneset":"GO_SIGNALING_ADAPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNALING_ADAPTOR_ACTIVITY","description":"The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity."} {"geneset":"GO_G_PROTEIN_BETA_GAMMA_SUBUNIT_COMPLEX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_BETA_GAMMA_SUBUNIT_COMPLEX_BINDING","description":"Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits."} {"geneset":"GO_DOPAMINE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOPAMINE_BINDING","description":"Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine."} {"geneset":"GO_SH3_SH2_ADAPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SH3_SH2_ADAPTOR_ACTIVITY","description":"Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68)."} {"geneset":"GO_RETINOL_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINOL_BINDING","description":"Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation."} {"geneset":"GO_INORGANIC_ANION_EXCHANGER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INORGANIC_ANION_EXCHANGER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out)."} {"geneset":"GO_RETINOL_DEHYDROGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RETINOL_DEHYDROGENASE_ACTIVITY","description":"Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+."} {"geneset":"GO_PHOSPHOLIPASE_C_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPASE_C_ACTIVITY","description":"Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate."} {"geneset":"GO_NUCLEOSOMAL_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOSOMAL_DNA_BINDING","description":"Interacting selectively and non-covalently with the DNA portion of a nucleosome."} {"geneset":"GO_LIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPASE_ACTIVITY","description":"Catalysis of the hydrolysis of a lipid or phospholipid."} {"geneset":"GO_PROTEIN_BINDING_INVOLVED_IN_CELL_CELL_ADHESION","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_BINDING_INVOLVED_IN_CELL_CELL_ADHESION","description":"Any protein binding that is involved in cell-cell adhesion."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_4_BISPHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_4_BISPHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions."} {"geneset":"GO_ACTIN_DEPENDENT_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_DEPENDENT_ATPASE_ACTIVITY","description":"Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of an actin filament to accelerate release of ADP and phosphate."} {"geneset":"GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","description":"Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."} {"geneset":"GO_METHYL_CPG_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METHYL_CPG_BINDING","description":"Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide."} {"geneset":"GO_TRANSLATION_REGULATOR_ACTIVITY_NUCLEIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSLATION_REGULATOR_ACTIVITY_NUCLEIC_ACID_BINDING","description":"Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome."} {"geneset":"GO_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_ACTIVITY","description":"Combining with an extracellular or intracellular messenger to initiate a change in cell activity."} {"geneset":"GO_ACTIN_MONOMER_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_MONOMER_BINDING","description":"Interacting selectively and non-covalently with monomeric actin, also known as G-actin."} {"geneset":"GO_REPRESSING_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_REPRESSING_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription."} {"geneset":"GO_POLYOL_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLYOL_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of a polyol from one side of the membrane to the other. A polyol is any polyhydric alcohol."} {"geneset":"GO_CHROMATIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHROMATIN_BINDING","description":"Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."} {"geneset":"GO_MYOSIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MYOSIN_BINDING","description":"Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments."} {"geneset":"GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_LINEAR_AMIDES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_LINEAR_AMIDES","description":"Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide."} {"geneset":"GO_CHEMOREPELLENT_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHEMOREPELLENT_ACTIVITY","description":"Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal."} {"geneset":"GO_MAP_KINASE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MAP_KINASE_KINASE_ACTIVITY","description":"Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate."} {"geneset":"GO_ANTIGEN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANTIGEN_BINDING","description":"Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen."} {"geneset":"GO_PROTEIN_DOMAIN_SPECIFIC_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_DOMAIN_SPECIFIC_BINDING","description":"Interacting selectively and non-covalently with a specific domain of a protein."} {"geneset":"GO_SODIUM_CHANNEL_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_CHANNEL_REGULATOR_ACTIVITY","description":"Modulates the activity of a sodium channel."} {"geneset":"GO_POLY_A_SPECIFIC_RIBONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POLY_A_SPECIFIC_RIBONUCLEASE_ACTIVITY","description":"Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS","description":"Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."} {"geneset":"GO_DOUBLE_STRANDED_RNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOUBLE_STRANDED_RNA_BINDING","description":"Interacting selectively and non-covalently with double-stranded RNA."} {"geneset":"GO_MHC_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MHC_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation."} {"geneset":"GO_POTASSIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_POTASSIUM_CHANNEL_ACTIVITY","description":"Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."} {"geneset":"GO_FATTY_ACID_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FATTY_ACID_LIGASE_ACTIVITY","description":"Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP."} {"geneset":"GO_APOLIPOPROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_APOLIPOPROTEIN_BINDING","description":"Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex."} {"geneset":"GO_LIPID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIPID_BINDING","description":"Interacting selectively and non-covalently with a lipid."} {"geneset":"GO_HISTONE_ACETYLTRANSFERASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_ACETYLTRANSFERASE_BINDING","description":"Interacting selectively and non-covalently with the enzyme histone acetyltransferase."} {"geneset":"GO_STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON","description":"The action of a molecule that contributes to the structural integrity of a cytoskeletal structure."} {"geneset":"GO_IGG_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_IGG_BINDING","description":"Interacting selectively and non-covalently with an immunoglobulin of an IgG isotype."} {"geneset":"GO_2_IRON_2_SULFUR_CLUSTER_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_2_IRON_2_SULFUR_CLUSTER_BINDING","description":"Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands."} {"geneset":"GO_ALPHA_ACTININ_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ALPHA_ACTININ_BINDING","description":"Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_SULFUR_GROUP_OF_DONORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_SULFUR_GROUP_OF_DONORS","description":"Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."} {"geneset":"GO_DEACETYLASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEACETYLASE_ACTIVITY","description":"Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule."} {"geneset":"GO_TUMOR_NECROSIS_FACTOR_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TUMOR_NECROSIS_FACTOR_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the tumor necrosis factor receptor."} {"geneset":"GO_FLAVIN_ADENINE_DINUCLEOTIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FLAVIN_ADENINE_DINUCLEOTIDE_BINDING","description":"Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS","description":"Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor)."} {"geneset":"GO_PROTEIN_N_TERMINUS_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_N_TERMINUS_BINDING","description":"Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue."} {"geneset":"GO_ANGIOTENSIN_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ANGIOTENSIN_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with an angiotensin receptor."} {"geneset":"GO_INWARD_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INWARD_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself."} {"geneset":"GO_GLUCOSYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUCOSYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid."} {"geneset":"GO_RIBONUCLEASE_P_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEASE_P_ACTIVITY","description":"Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor."} {"geneset":"GO_P53_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_P53_BINDING","description":"Interacting selectively and non-covalently with one of the p53 family of proteins."} {"geneset":"GO_PROTON_TRANSPORTING_ATP_SYNTHASE_ACTIVITY_ROTATIONAL_MECHANISM","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTON_TRANSPORTING_ATP_SYNTHASE_ACTIVITY_ROTATIONAL_MECHANISM","description":"Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism."} {"geneset":"GO_PEPTIDE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PEPTIDE_RECEPTOR_ACTIVITY","description":"Combining with an extracellular or intracellular peptide to initiate a change in cell activity."} {"geneset":"GO_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYMPORTER_ACTIVITY","description":"Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy."} {"geneset":"GO_FRIZZLED_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_FRIZZLED_BINDING","description":"Interacting selectively and non-covalently with the frizzled (fz) receptor."} {"geneset":"GO_RNA_POLYMERASE_II_TRANSCRIPTION_COFACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_TRANSCRIPTION_COFACTOR_ACTIVITY","description":"Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery."} {"geneset":"GO_RNA_POLYMERASE_II_CARBOXY_TERMINAL_DOMAIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_CARBOXY_TERMINAL_DOMAIN_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats."} {"geneset":"GO_ENDORIBONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDORIBONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks."} {"geneset":"GO_NEUROTROPHIN_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTROPHIN_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a neurotrophin receptor."} {"geneset":"GO_UBIQUITIN_LIKE_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_UBIQUITIN_LIKE_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY","description":"Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated."} {"geneset":"GO_PHOSPHOLIPID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPID_BINDING","description":"Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester."} {"geneset":"GO_C_ACYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_C_ACYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule."} {"geneset":"GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY","description":"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears."} {"geneset":"GO_G_PROTEIN_COUPLED_CHEMOATTRACTANT_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_CHEMOATTRACTANT_RECEPTOR_ACTIVITY","description":"Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."} {"geneset":"GO_SEQUENCE_SPECIFIC_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEQUENCE_SPECIFIC_DNA_BINDING","description":"Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding."} {"geneset":"GO_GTP_DEPENDENT_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GTP_DEPENDENT_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of GTP."} {"geneset":"GO_TRANSCRIPTION_COREPRESSOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_COREPRESSOR_ACTIVITY","description":"Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery."} {"geneset":"GO_DEATH_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEATH_RECEPTOR_ACTIVITY","description":"Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death."} {"geneset":"GO_RIBONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBONUCLEASE_ACTIVITY","description":"Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA."} {"geneset":"GO_MISFOLDED_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MISFOLDED_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with a misfolded protein."} {"geneset":"GO_LAMININ_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LAMININ_BINDING","description":"Interacting selectively and non-covalently with laminins, glycoproteins that are major constituents of the basement membrane of cells."} {"geneset":"GO_GLUTAMATE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GLUTAMATE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a glutamate receptor."} {"geneset":"GO_CYTOKINE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_RECEPTOR_ACTIVITY","description":"Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."} {"geneset":"GO_ACID_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACID_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum."} {"geneset":"GO_ENDOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_REDUCED_FLAVIN_OR_FLAVOPROTEIN_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_OF_OXYGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_REDUCED_FLAVIN_OR_FLAVOPROTEIN_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_OF_OXYGEN","description":"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor."} {"geneset":"GO_ARYLSULFATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARYLSULFATASE_ACTIVITY","description":"Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate."} {"geneset":"GO_NOTCH_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NOTCH_BINDING","description":"Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor."} {"geneset":"GO_CATION_AMINO_ACID_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_AMINO_ACID_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in)."} {"geneset":"GO_DEAMINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DEAMINASE_ACTIVITY","description":"Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3)."} {"geneset":"GO_THYROID_HORMONE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THYROID_HORMONE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a thyroid hormone receptor."} {"geneset":"GO_RECEPTOR_SIGNALING_PROTEIN_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_SIGNALING_PROTEIN_ACTIVITY","description":"Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell."} {"geneset":"GO_METALLOAMINOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METALLOAMINOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."} {"geneset":"GO_GAP_JUNCTION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GAP_JUNCTION_CHANNEL_ACTIVITY","description":"A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes."} {"geneset":"GO_DOPAMINE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DOPAMINE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a dopamine receptor."} {"geneset":"GO_SIGNALING_PATTERN_RECOGNITION_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SIGNALING_PATTERN_RECOGNITION_RECEPTOR_ACTIVITY","description":"Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity."} {"geneset":"GO_NEUROPEPTIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROPEPTIDE_BINDING","description":"Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators)."} {"geneset":"GO_HIGH_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HIGH_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded."} {"geneset":"GO_GAMMA_CATENIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GAMMA_CATENIN_BINDING","description":"Interacting selectively and non-covalently with the gamma subunit of the catenin complex."} {"geneset":"GO_CALCIUM_DEPENDENT_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_DEPENDENT_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium."} {"geneset":"GO_TBP_CLASS_PROTEIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TBP_CLASS_PROTEIN_BINDING","description":"Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs)."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H_QUINONE_OR_SIMILAR_COMPOUND_AS_ACCEPTOR","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H_QUINONE_OR_SIMILAR_COMPOUND_AS_ACCEPTOR","description":"Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule."} {"geneset":"GO_TAU_PROTEIN_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TAU_PROTEIN_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein."} {"geneset":"GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC","description":"Interacting selectively and non-covalently with a specific DNA sequence in an RNA polymerase II (Pol II) core promoter, the region composed of the transcription start site and binding sites for transcription factors of the Pol II basal transcription machinery, in order to modulate transcription by Pol II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."} {"geneset":"GO_RIBOSOME_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RIBOSOME_BINDING","description":"Interacting selectively and non-covalently with any part of a ribosome."} {"geneset":"GO_TRANSCRIPTION_COACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSCRIPTION_COACTIVATOR_ACTIVITY","description":"Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery."} {"geneset":"GO_RECEPTOR_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_REGULATOR_ACTIVITY","description":"The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed."} {"geneset":"GO_LYSINE_N_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LYSINE_N_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue."} {"geneset":"GO_SODIUM_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_ION_BINDING","description":"Interacting selectively and non-covalently with sodium ions (Na+)."} {"geneset":"GO_C_C_CHEMOKINE_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_C_C_CHEMOKINE_RECEPTOR_ACTIVITY","description":"Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY","description":"Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced."} {"geneset":"GO_MONOSACCHARIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOSACCHARIDE_BINDING","description":"Interacting selectively and non-covalently with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."} {"geneset":"GO_CORE_PROMOTER_PROXIMAL_REGION_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORE_PROMOTER_PROXIMAL_REGION_DNA_BINDING","description":"Interacting selectively and non-covalently with a region of DNA that is in cis with and relatively close to the core promoter. The transcribed region might be described as a gene, cistron, or operon."} {"geneset":"GO_EPHRIN_RECEPTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPHRIN_RECEPTOR_ACTIVITY","description":"Combining with an ephrin to initiate a change in cell activity."} {"geneset":"GO_ATPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ATPASE_ACTIVITY","description":"Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction."} {"geneset":"GO_GTPASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GTPASE_BINDING","description":"Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP."} {"geneset":"GO_PRE_MRNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PRE_MRNA_BINDING","description":"Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule."} {"geneset":"GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY","description":"Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."} {"geneset":"GO_G_PROTEIN_COUPLED_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_G_PROTEIN_COUPLED_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a G-protein coupled receptor."} {"geneset":"GO_LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS","description":"Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."} {"geneset":"GO_CARBON_OXYGEN_LYASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARBON_OXYGEN_LYASE_ACTIVITY","description":"Catalysis of the breakage of a carbon-oxygen bond."} {"geneset":"GO_ADENYL_NUCLEOTIDE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ADENYL_NUCLEOTIDE_BINDING","description":"Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate."} {"geneset":"GO_EXTRACELLULAR_GLUTAMATE_GATED_ION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXTRACELLULAR_GLUTAMATE_GATED_ION_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts."} {"geneset":"GO_SOLUTE_SODIUM_SYMPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SOLUTE_SODIUM_SYMPORTER_ACTIVITY","description":"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in)."} {"geneset":"GO_PHOSPHATIDATE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDATE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS","description":"Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor)."} {"geneset":"GO_NUCLEOTIDE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDE_KINASE_ACTIVITY","description":"Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate."} {"geneset":"GO_NEUROTRANSMITTER_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROTRANSMITTER_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell."} {"geneset":"GO_TRNA_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRNA_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule."} {"geneset":"GO_HISTONE_METHYLTRANSFERASE_ACTIVITY_H3_K4_SPECIFIC_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_METHYLTRANSFERASE_ACTIVITY_H3_K4_SPECIFIC_","description":"Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein."} {"geneset":"GO_CELL_ADHESION_MOLECULE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_ADHESION_MOLECULE_BINDING","description":"Interacting selectively and non-covalently with a cell adhesion molecule."} {"geneset":"GO_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."} {"geneset":"GO_RECEPTOR_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_INHIBITOR_ACTIVITY","description":"The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased."} {"geneset":"GO_CADHERIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CADHERIN_BINDING","description":"Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion."} {"geneset":"GO_SEMAPHORIN_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SEMAPHORIN_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with semaphorin receptors."} {"geneset":"GO_METALLOENDOPEPTIDASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_METALLOENDOPEPTIDASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity."} {"geneset":"GO_EPHRIN_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EPHRIN_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with an ephrin receptor."} {"geneset":"GO_CHLORIDE_CHANNEL_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CHLORIDE_CHANNEL_REGULATOR_ACTIVITY","description":"Modulates the activity of a chloride channel."} {"geneset":"GO_OPSONIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OPSONIN_BINDING","description":"Interacting selectively and non-covalently with an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material."} {"geneset":"GO_DNA_HELICASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_HELICASE_ACTIVITY","description":"Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix."} {"geneset":"GO_AMMONIUM_ION_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMMONIUM_ION_BINDING","description":"Interacting selectively and non-covalently with ammonium ions (NH4+)."} {"geneset":"GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING","description":"Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II."} {"geneset":"GO_EXONUCLEASE_ACTIVITY_ACTIVE_WITH_EITHER_RIBO_OR_DEOXYRIBONUCLEIC_ACIDS_AND_PRODUCING_5_PHOSPHOMONOESTERS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXONUCLEASE_ACTIVITY_ACTIVE_WITH_EITHER_RIBO_OR_DEOXYRIBONUCLEIC_ACIDS_AND_PRODUCING_5_PHOSPHOMONOESTERS","description":"Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters."} {"geneset":"GO_ASPARTIC_TYPE_PEPTIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ASPARTIC_TYPE_PEPTIDASE_ACTIVITY","description":"Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile."} {"geneset":"GO_RNA_POLYMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_ACTIVITY","description":"Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template."} {"geneset":"GO_PROTEIN_PHOSPHATASE_2A_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_PHOSPHATASE_2A_BINDING","description":"Interacting selectively and non-covalently with the enzyme protein phosphatase 2A."} {"geneset":"GO_MONOCARBOXYLIC_ACID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MONOCARBOXYLIC_ACID_BINDING","description":"Interacting selectively and non-covalently with a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-)."} {"geneset":"GO_ISOMERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ISOMERASE_ACTIVITY","description":"Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5."} {"geneset":"GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS","description":"Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds."} {"geneset":"GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with the platelet-derived growth factor receptor."} {"geneset":"GO_DNA_POLYMERASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_DNA_POLYMERASE_BINDING","description":"Interacting selectively and non-covalently with a DNA polymerase."} {"geneset":"GO_NUCLEOBASE_CONTAINING_COMPOUND_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOBASE_CONTAINING_COMPOUND_KINASE_ACTIVITY","description":"Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate."} {"geneset":"GO_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSPORTER_ACTIVITY","description":"Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells."} {"geneset":"GO_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY","description":"Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."} {"geneset":"GO_CYTOKINE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_ACTIVITY","description":"Functions to control the survival, growth, differentiation and effector function of tissues and cells."} {"geneset":"GO_EXODEOXYRIBONUCLEASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_EXODEOXYRIBONUCLEASE_ACTIVITY","description":"Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule."} {"geneset":"GO_4_IRON_4_SULFUR_CLUSTER_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_4_IRON_4_SULFUR_CLUSTER_BINDING","description":"Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_NAD_P_H_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_OF_OXYGEN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_NAD_P_H_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_OF_OXYGEN","description":"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor."} {"geneset":"GO_PHOSPHOLIPASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHOLIPASE_ACTIVITY","description":"Catalysis of the hydrolysis of a glycerophospholipid."} {"geneset":"GO_ARACHIDONIC_ACID_MONOOXYGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARACHIDONIC_ACID_MONOOXYGENASE_ACTIVITY","description":"Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water."} {"geneset":"GO_N_ACETYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_N_ACETYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule."} {"geneset":"GO_HYDROLASE_ACTIVITY_HYDROLYZING_O_GLYCOSYL_COMPOUNDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_HYDROLYZING_O_GLYCOSYL_COMPOUNDS","description":"Catalysis of the hydrolysis of any O-glycosyl bond."} {"geneset":"GO_MACROMOLECULAR_COMPLEX_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MACROMOLECULAR_COMPLEX_BINDING","description":"Interacting selectively and non-covalently with any macromolecular complex."} {"geneset":"GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY_INTERCONVERTING_ALDOSES_AND_KETOSES","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY_INTERCONVERTING_ALDOSES_AND_KETOSES","description":"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears."} {"geneset":"GO_ACID_THIOL_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACID_THIOL_LIGASE_ACTIVITY","description":"Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."} {"geneset":"GO_STRUCTURAL_MOLECULE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRUCTURAL_MOLECULE_ACTIVITY","description":"The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell."} {"geneset":"GO_HISTONE_DEACETYLASE_ACTIVITY_H3_K14_SPECIFIC_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_DEACETYLASE_ACTIVITY_H3_K14_SPECIFIC_","description":"Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein."} {"geneset":"GO_RNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_BINDING","description":"Interacting selectively and non-covalently with an RNA molecule or a portion thereof."} {"geneset":"GO_ODORANT_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ODORANT_BINDING","description":"Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell."} {"geneset":"GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY","description":"Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_3_4_5_TRISPHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_3_4_5_TRISPHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions."} {"geneset":"GO_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_DNA_BINDING","description":"Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter."} {"geneset":"GO_CYTOKINE_RECEPTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYTOKINE_RECEPTOR_BINDING","description":"Interacting selectively and non-covalently with a cytokine receptor."} {"geneset":"GO_PHOSPHATASE_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATASE_REGULATOR_ACTIVITY","description":"Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule."} {"geneset":"GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH_GROUP_OF_DONORS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH_GROUP_OF_DONORS","description":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."} {"geneset":"GO_TUMOR_NECROSIS_FACTOR_RECEPTOR_SUPERFAMILY_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TUMOR_NECROSIS_FACTOR_RECEPTOR_SUPERFAMILY_BINDING","description":"Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily."} {"geneset":"GO_PROTEIN_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_CHANNEL_ACTIVITY","description":"Enables the energy-independent facilitated diffusion, mediated by passage of proteins through a transmembrane aqueous pore or channel."} {"geneset":"GO_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING","description":"Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon."} {"geneset":"GO_HISTONE_KINASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_KINASE_ACTIVITY","description":"Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes."} {"geneset":"GO_ARMADILLO_REPEAT_DOMAIN_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ARMADILLO_REPEAT_DOMAIN_BINDING","description":"Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation."} {"geneset":"GO_CATION_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CATION_CHANNEL_ACTIVITY","description":"Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient."} {"geneset":"GO_RAB_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_RAB_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY","description":"Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rab family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."} {"geneset":"GO_OXIDIZED_NAD_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_OXIDIZED_NAD_BINDING","description":"Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions."} {"geneset":"GO_GROWTH_FACTOR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_GROWTH_FACTOR_BINDING","description":"Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate."} {"geneset":"GO_CALCIUM_CHANNEL_REGULATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_CHANNEL_REGULATOR_ACTIVITY","description":"Modulates the activity of a calcium channel."} {"geneset":"GO_THIOESTERASE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_THIOESTERASE_BINDING","description":"Interacting selectively and non-covalently with any thioesterase enzyme."} {"geneset":"GO_INOSITOL_TRISPHOSPHATE_PHOSPHATASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_INOSITOL_TRISPHOSPHATE_PHOSPHATASE_ACTIVITY","description":"Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate."} {"geneset":"GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS","description":"Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)."} {"geneset":"GO_HYDROLASE_ACTIVITY_ACTING_ON_ETHER_BONDS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HYDROLASE_ACTIVITY_ACTING_ON_ETHER_BONDS","description":"Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively."} {"geneset":"GO_ACYL_COA_DEHYDROGENASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACYL_COA_DEHYDROGENASE_ACTIVITY","description":"Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor."} {"geneset":"GO_LIGASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_LIGASE_ACTIVITY","description":"Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."} {"geneset":"GO_HEXOSAMINIDASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HEXOSAMINIDASE_ACTIVITY","description":"Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides."} {"geneset":"GO_MRNA_3_UTR_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_MRNA_3_UTR_BINDING","description":"Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule."} {"geneset":"GO_PHOSPHATIDYLINOSITOL_4_PHOSPHATE_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PHOSPHATIDYLINOSITOL_4_PHOSPHATE_BINDING","description":"Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position."} {"geneset":"GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS","description":"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process."} {"geneset":"GO_SODIUM_CHANNEL_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_CHANNEL_ACTIVITY","description":"Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."} {"geneset":"GO_STRUCTURE_SPECIFIC_DNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_STRUCTURE_SPECIFIC_DNA_BINDING","description":"Interacting selectively and non-covalently with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."} {"geneset":"GO_COENZYME_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_COENZYME_BINDING","description":"Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed."} {"geneset":"GO_SNORNA_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SNORNA_BINDING","description":"Interacting selectively and non-covalently with small nucleolar RNA."} {"geneset":"GO_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY","description":"Enables the transfer of sodium ions (Na+) from one side of a membrane to the other."} {"geneset":"GO_NUCLEOTIDYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_NUCLEOTIDYLTRANSFERASE_ACTIVITY","description":"Catalysis of the transfer of a nucleotidyl group to a reactant."} {"geneset":"GO_CALCIUM_DEPENDENT_PHOSPHOLIPID_BINDING","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CALCIUM_DEPENDENT_PHOSPHOLIPID_BINDING","description":"Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium."} {"geneset":"GO_CYSTEINE_TYPE_ENDOPEPTIDASE_REGULATOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_CYSTEINE_TYPE_ENDOPEPTIDASE_REGULATOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS","description":"Modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process."} {"geneset":"GO_HISTONE_METHYLTRANSFERASE_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_HISTONE_METHYLTRANSFERASE_ACTIVITY","description":"Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue."} {"geneset":"GO_PROTEIN_TYROSINE_KINASE_ACTIVATOR_ACTIVITY","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTEIN_TYROSINE_KINASE_ACTIVATOR_ACTIVITY","description":"Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein."} {"geneset":"GLI1_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GLI1_UP.V1_DN","description":"Genes down-regulated in RK3E cells (kidney epithelium) over-expressing GLI1 [Gene ID=2735]."} {"geneset":"GLI1_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GLI1_UP.V1_UP","description":"Genes up-regulated in RK3E cells (kidney epithelium) over-expressing GLI1 [Gene ID=2735]."} {"geneset":"E2F1_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1_UP.V1_DN","description":"Genes down-regulated in mouse fibroblasts over-expressing E2F1 [Gene ID=1869] gene."} {"geneset":"E2F1_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F1_UP.V1_UP","description":"Genes up-regulated in mouse fibroblasts over-expressing E2F1 [Gene ID=1869] gene."} {"geneset":"EGFR_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EGFR_UP.V1_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable EGFR [Gene ID=1956]."} {"geneset":"EGFR_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EGFR_UP.V1_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable EGFR [Gene ID=1956]."} {"geneset":"ERB2_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ERB2_UP.V1_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable ERBB2 [Gene ID=2064]."} {"geneset":"ERB2_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ERB2_UP.V1_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable ERBB2 [Gene ID=2064]."} {"geneset":"GCNP_SHH_UP_EARLY.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCNP_SHH_UP_EARLY.V1_DN","description":"Genes down-regulated in granule cell neuron precursors (GCNPs) after stimulation with Shh for 3h."} {"geneset":"GCNP_SHH_UP_EARLY.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCNP_SHH_UP_EARLY.V1_UP","description":"Genes up-regulated in granule cell neuron precursors (GCNPs) after stimulation with Shh for 3h."} {"geneset":"GCNP_SHH_UP_LATE.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCNP_SHH_UP_LATE.V1_DN","description":"Genes down-regulated in granule cell neuron precursors (GCNPs) after stimulation with Shh for 24h."} {"geneset":"GCNP_SHH_UP_LATE.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GCNP_SHH_UP_LATE.V1_UP","description":"Genes up-regulated in granule cell neuron precursors (GCNPs) after stimulation with Shh for 24h."} {"geneset":"RAPA_EARLY_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAPA_EARLY_UP.V1_DN","description":"Genes down-regulated in BJAB (lymphoma) cells by rapamycin (sirolimus) [PubChem = 6610346]."} {"geneset":"RAPA_EARLY_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAPA_EARLY_UP.V1_UP","description":"Genes up-regulated in BJAB (lymphoma) cells by rapamycin (sirolimus) [PubChem = 6610346]."} {"geneset":"HINATA_NFKB_IMMU_INF","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HINATA_NFKB_IMMU_INF","description":"Immune or inflammatory genes induced by NF-kappaB in primary keratinocytes and fibroblasts."} {"geneset":"HINATA_NFKB_MATRIX","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HINATA_NFKB_MATRIX","description":"Matrix, adhesion or cytoskeleton genes induced by NF-kappaB in primary keratinocytes and fibroblasts."} {"geneset":"CYCLIN_D1_KE_.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CYCLIN_D1_KE_.V1_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) over-expressing a mutant K112E form of CCND1 [Gene ID=595] gene."} {"geneset":"CYCLIN_D1_KE_.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CYCLIN_D1_KE_.V1_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) over-expressing a mutant K112E form of CCND1 [Gene ID=595] gene."} {"geneset":"CYCLIN_D1_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CYCLIN_D1_UP.V1_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) over-expressing CCND1 [Gene ID=595] gene."} {"geneset":"CYCLIN_D1_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CYCLIN_D1_UP.V1_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) over-expressing CCND1 [Gene ID=595] gene."} {"geneset":"CSR_EARLY_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CSR_EARLY_UP.V1_DN","description":"Genes down-regulated in early serum response of CRL 2091 cells (foreskin fibroblasts)."} {"geneset":"CSR_EARLY_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CSR_EARLY_UP.V1_UP","description":"Genes up-regulated in early serum response of CRL 2091 cells (foreskin fibroblasts)."} {"geneset":"CSR_LATE_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CSR_LATE_UP.V1_DN","description":"Genes down-regulated in late serum response of CRL 2091 cells (foreskin fibroblasts)."} {"geneset":"CSR_LATE_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CSR_LATE_UP.V1_UP","description":"Genes up-regulated in late serum response of CRL 2091 cells (foreskin fibroblasts)."} {"geneset":"AKT_UP_MTOR_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AKT_UP_MTOR_DN.V1_DN","description":"Genes down-regulated by everolimus [PubChem = 6442177] in mouse prostate tissue transgenically expressing human AKT1 gene [Gene ID=207] vs untreated controls."} {"geneset":"AKT_UP_MTOR_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AKT_UP_MTOR_DN.V1_UP","description":"Genes up-regulated by everolimus [PubChem = 6442177] in mouse prostate tissue transgenically expressing human AKT1 gene [Gene ID=207] vs untreated controls."} {"geneset":"AKT_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AKT_UP.V1_DN","description":"Genes down-regulated in mouse prostate by transgenic expression of human AKT1 gene [Gene ID=207] vs controls."} {"geneset":"AKT_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/AKT_UP.V1_UP","description":"Genes up-regulated in mouse prostate by transgenic expression of human AKT1 gene [Gene ID=207] vs controls."} {"geneset":"MTOR_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MTOR_UP.V1_DN","description":"Genes down-regulated by everolimus [PubChem = 6442177] in prostate tissue."} {"geneset":"MTOR_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MTOR_UP.V1_UP","description":"Genes up-regulated by everolimus [PubChem = 6442177] in prostate tissue."} {"geneset":"PIGF_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PIGF_UP.V1_DN","description":"Genes down-regulated in HUVEC cells (endothelium) by treatment with PIGF [Gene ID=5281]."} {"geneset":"PIGF_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PIGF_UP.V1_UP","description":"Genes up-regulated in HUVEC cells (endothelium) by treatment with PIGF [Gene ID=5281]."} {"geneset":"VEGF_A_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VEGF_A_UP.V1_DN","description":"Genes down-regulated in HUVEC cells (endothelium) by treatment with VEGFA [Gene ID=7422]."} {"geneset":"VEGF_A_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/VEGF_A_UP.V1_UP","description":"Genes up-regulated in HUVEC cells (endothelium) by treatment with VEGFA [Gene ID=7422]."} {"geneset":"BCAT_GDS748_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BCAT_GDS748_DN","description":"Genes down-regulated in HEK293 cells (kidney fibroblasts) expressing constitutively active form of CTNNB1 [Gene ID=1499] gene."} {"geneset":"BCAT_GDS748_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BCAT_GDS748_UP","description":"Genes up-regulated in HEK293 cells (kidney fibroblasts) expressing constitutively active form of CTNNB1 [Gene ID=1499] gene."} {"geneset":"BCAT.100_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BCAT.100_UP.V1_DN","description":"Genes down-regulated in HEK293 cells (kidney fibroblasts) expressing constitutively active form of CTNNB1 [Gene ID=1499] gene."} {"geneset":"BCAT.100_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BCAT.100_UP.V1_UP","description":"Genes up-regulated in HEK293 cells (kidney fibroblasts) expressing constitutively active form of CTNNB1 [Gene ID=1499] gene."} {"geneset":"ATF2_S_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF2_S_UP.V1_DN","description":"Genes down-regulated in myometrial cells over-expressing a shortened splice form of ATF2 [Gene ID=1386] gene."} {"geneset":"ATF2_S_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF2_S_UP.V1_UP","description":"Genes up-regulated in myometrial cells over-expressing a shortened splice form of ATF2 [Gene ID=1386] gene."} {"geneset":"ATF2_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF2_UP.V1_DN","description":"Genes down-regulated in myometrial cells over-expressing ATF2 [Gene ID=1386] gene."} {"geneset":"ATF2_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATF2_UP.V1_UP","description":"Genes up-regulated in myometrial cells over-expressing ATF2 [Gene ID=1386] gene."} {"geneset":"WNT_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WNT_UP.V1_DN","description":"Genes down-regulated in C57MG cells (mammary epithelium) by over-expression of WNT1 [Gene ID=7471] gene."} {"geneset":"WNT_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/WNT_UP.V1_UP","description":"Genes up-regulated in C57MG cells (mammary epithelium) by over-expression of WNT1 [Gene ID=7471] gene."} {"geneset":"ATM_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATM_DN.V1_DN","description":"Genes down-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of ATM [Gene ID=472] gene by RNAi."} {"geneset":"ATM_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ATM_DN.V1_UP","description":"Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of ATM [Gene ID=472] gene by RNAi."} {"geneset":"P53_DN.V2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/P53_DN.V2_DN","description":"Genes down-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of TP53 [Gene ID=7157] gene by RNAi."} {"geneset":"P53_DN.V2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/P53_DN.V2_UP","description":"Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of TP53 [Gene ID=7157] gene by RNAi."} {"geneset":"RELA_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RELA_DN.V1_DN","description":"Genes down-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of RELA [Gene ID=5970] gene by RNAi."} {"geneset":"RELA_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RELA_DN.V1_UP","description":"Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of RELA [Gene ID=5970] gene by RNAi."} {"geneset":"P53_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/P53_DN.V1_DN","description":"Genes down-regulated in NCI-60 panel of cell lines with mutated TP53 [Gene ID=7157]."} {"geneset":"P53_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/P53_DN.V1_UP","description":"Genes up-regulated in NCI-60 panel of cell lines with mutated TP53 [Gene ID=7157]."} {"geneset":"BCAT_BILD_ET_AL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BCAT_BILD_ET_AL_DN","description":"Genes down-regulated in primary epithelial breast cancer cell culture over-expressing activated CTNNB1 [Gene ID=1499] gene."} {"geneset":"BCAT_BILD_ET_AL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BCAT_BILD_ET_AL_UP","description":"Genes up-regulated in primary epithelial breast cancer cell culture over-expressing activated CTNNB1 [Gene ID=1499] gene."} {"geneset":"E2F3_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F3_UP.V1_DN","description":"Genes down-regulated in primary epithelial breast cancer cell culture over-expressing E2F3 [Gene ID=1871] gene."} {"geneset":"E2F3_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/E2F3_UP.V1_UP","description":"Genes up-regulated in primary epithelial breast cancer cell culture over-expressing E2F3 [Gene ID=1871] gene."} {"geneset":"MYC_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYC_UP.V1_DN","description":"Genes down-regulated in primary epithelial breast cancer cell culture over-expressing MYC [Gene ID=4609] gene."} {"geneset":"MYC_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MYC_UP.V1_UP","description":"Genes up-regulated in primary epithelial breast cancer cell culture over-expressing MYC [Gene ID=4609] gene."} {"geneset":"SRC_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRC_UP.V1_DN","description":"Genes down-regulated in primary epithelial breast cancer cell culture over-expressing SRC [Gene ID=6714] gene."} {"geneset":"SRC_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SRC_UP.V1_UP","description":"Genes up-regulated in primary epithelial breast cancer cell culture over-expressing SRC [Gene ID=6714] gene."} {"geneset":"SNF5_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SNF5_DN.V1_DN","description":"Genes down-regulated in MEF cells (embryonic fibroblasts) with knockout of SNF5 [Gene ID=6598] gene."} {"geneset":"SNF5_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SNF5_DN.V1_UP","description":"Genes up-regulated in MEF cells (embryonic fibroblasts) with knockout of SNF5 [Gene ID=6598] gene."} {"geneset":"CAMP_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAMP_UP.V1_DN","description":"Genes down-regulated in primary thyrocyte cultures in response to cAMP signaling pathway activation by thyrotropin (TSH)."} {"geneset":"CAMP_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAMP_UP.V1_UP","description":"Genes up-regulated in primary thyrocyte cultures in response to cAMP signaling pathway activation by thyrotropin (TSH)."} {"geneset":"LTE2_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LTE2_UP.V1_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) and long-term adapted for estrogen-independent growth."} {"geneset":"LTE2_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LTE2_UP.V1_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) and long-term adapted for estrogen-independent growth."} {"geneset":"MEK_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEK_UP.V1_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active MAP2K1 [Gene ID=5604] gene."} {"geneset":"MEK_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEK_UP.V1_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active MAP2K1 [Gene ID=5604] gene."} {"geneset":"RAF_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAF_UP.V1_DN","description":"Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene."} {"geneset":"RAF_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RAF_UP.V1_UP","description":"Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene."} {"geneset":"PRC1_BMI_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRC1_BMI_UP.V1_DN","description":"Genes down-regulated in TIG3 cells (fibroblasts) upon knockdown of BMI1 [Gene ID=648] gene."} {"geneset":"PRC1_BMI_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRC1_BMI_UP.V1_UP","description":"Genes up-regulated in TIG3 cells (fibroblasts) upon knockdown of BMI1 [Gene ID=648] gene."} {"geneset":"PRC2_EED_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRC2_EED_UP.V1_DN","description":"Genes down-regulated in TIG3 cells (fibroblasts) upon knockdown of EED [Gene ID=8726] gene."} {"geneset":"PRC2_EED_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRC2_EED_UP.V1_UP","description":"Genes up-regulated in TIG3 cells (fibroblasts) upon knockdown of EED [Gene ID=8726] gene."} {"geneset":"PRC2_EZH2_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRC2_EZH2_UP.V1_DN","description":"Genes down-regulated in TIG3 cells (fibroblasts) upon knockdown of EZH2 [Gene ID=2146] gene."} {"geneset":"PRC2_EZH2_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRC2_EZH2_UP.V1_UP","description":"Genes up-regulated in TIG3 cells (fibroblasts) upon knockdown of EZH2 [Gene ID=2146] gene."} {"geneset":"PRC2_SUZ12_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRC2_SUZ12_UP.V1_DN","description":"Genes down-regulated in TIG3 cells (fibroblasts) upon knockdown of SUZ12 [Gene ID=23512] gene."} {"geneset":"PRC2_SUZ12_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PRC2_SUZ12_UP.V1_UP","description":"Genes up-regulated in TIG3 cells (fibroblasts) upon knockdown of SUZ12 [Gene ID=23512] gene."} {"geneset":"JNK_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JNK_DN.V1_DN","description":"Genes down-regulated in JNK inhibitor-treated (SP600125[PubChem=8515]) keratinocytes."} {"geneset":"JNK_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JNK_DN.V1_UP","description":"Genes up-regulated in JNK inhibitor-treated (SP600125[PubChem=8515]) keratinocytes."} {"geneset":"BRCA1_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRCA1_DN.V1_DN","description":"Genes down-regulated in MCF10A cells (breast cancer) upon knockdown of BRCA1 [Gene ID=672] gene by RNAi."} {"geneset":"BRCA1_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BRCA1_DN.V1_UP","description":"Genes up-regulated in MCF10A cells (breast cancer) upon knockdown of BRCA1 [Gene ID=672] gene by RNAi."} {"geneset":"CTIP_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTIP_DN.V1_DN","description":"Genes down-regulated in MCF10A cells (breast cancer) upon knockdown of RBBP8 [Gene ID=RBBP8] gene by RNAi."} {"geneset":"CTIP_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CTIP_DN.V1_UP","description":"Genes up-regulated in MCF10A cells (breast cancer) upon knockdown of RBBP8 [Gene ID=RBBP8] gene by RNAi."} {"geneset":"PKCA_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PKCA_DN.V1_DN","description":"Genes down-regulated in small intenstine in PRKCA [Gene ID=5578] knockout mice."} {"geneset":"PKCA_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PKCA_DN.V1_UP","description":"Genes up-regulated in small intenstine in PRKCA [Gene ID=5578] knockout mice."} {"geneset":"MTOR_UP.N4.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MTOR_UP.N4.V1_DN","description":"Genes down-regulated in CEM-C1 cells (T-CLL) in comparison of control vs rapamycin (sirolimus) [PubChem=6610346], an mTOR pathway inhibitor."} {"geneset":"MTOR_UP.N4.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MTOR_UP.N4.V1_UP","description":"Genes up-regulated in CEM-C1 cells (T-CLL) in comparison of control vs rapamycin (sirolimus) [PubChem=6610346], an mTOR pathway inhibitor."} {"geneset":"PTEN_DN.V2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PTEN_DN.V2_DN","description":"Genes down-regulated in HCT116 cells (colon carcinoma) upon knockdown of PTEN [Gene ID=5728] by RNAi."} {"geneset":"PTEN_DN.V2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PTEN_DN.V2_UP","description":"Genes up-regulated in HCT116 cells (colon carcinoma) upon knockdown of PTEN [Gene ID=5728] by RNAi."} {"geneset":"DCA_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DCA_UP.V1_DN","description":"Genes down-regulated in A549 lung carcinoma and M059K glioblastoma cells treated with dichloroacetate [PubChem=6597]."} {"geneset":"DCA_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/DCA_UP.V1_UP","description":"Genes up-regulated in A549 lung carcinoma and M059K glioblastoma cells treated with dichloroacetate [PubChem=6597]."} {"geneset":"ESC_J1_UP_EARLY.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ESC_J1_UP_EARLY.V1_DN","description":"Genes down-regulated during early stages of differentiation of embryoid bodies from J1 embryonic stem cells."} {"geneset":"ESC_J1_UP_EARLY.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ESC_J1_UP_EARLY.V1_UP","description":"Genes up-regulated during early stages of differentiation of embryoid bodies from J1 embryonic stem cells."} {"geneset":"ESC_J1_UP_LATE.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ESC_J1_UP_LATE.V1_DN","description":"Genes down-regulated during late stages of differentiation of embryoid bodies from J1 embryonic stem cells."} {"geneset":"ESC_J1_UP_LATE.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ESC_J1_UP_LATE.V1_UP","description":"Genes up-regulated during late stages of differentiation of embryoid bodies from J1 embryonic stem cells."} {"geneset":"ESC_V6.5_UP_EARLY.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ESC_V6.5_UP_EARLY.V1_DN","description":"Genes down-regulated during early stages of differentiation of embryoid bodies from V6.5 embryonic stem cells."} {"geneset":"ESC_V6.5_UP_EARLY.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ESC_V6.5_UP_EARLY.V1_UP","description":"Genes up-regulated during early stages of differentiation of embryoid bodies from V6.5 embryonic stem cells."} {"geneset":"ESC_V6.5_UP_LATE.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ESC_V6.5_UP_LATE.V1_DN","description":"Genes down-regulated during late stages of differentiation of embryoid bodies from V6.5 embryonic stem cells."} {"geneset":"ESC_V6.5_UP_LATE.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ESC_V6.5_UP_LATE.V1_UP","description":"Genes up-regulated during late stages of differentiation of embryoid bodies from V6.5 embryonic stem cells."} {"geneset":"ALK_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALK_DN.V1_DN","description":"Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of ALK [Gene ID=238] gene by RNAi."} {"geneset":"ALK_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/ALK_DN.V1_UP","description":"Genes up-regulated in DAOY cells (medulloblastoma) upon knockdown of ALK [Gene ID=238] gene by RNAi."} {"geneset":"BMI1_DN_MEL18_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BMI1_DN_MEL18_DN.V1_DN","description":"Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 and PCGF2 [Gene ID=648, 7703] genes by RNAi."} {"geneset":"BMI1_DN_MEL18_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BMI1_DN_MEL18_DN.V1_UP","description":"Genes up-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 and PCGF2 [Gene ID=648, 7703] genes by RNAi."} {"geneset":"BMI1_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BMI1_DN.V1_DN","description":"Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 [Gene ID=648] gene by RNAi."} {"geneset":"BMI1_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/BMI1_DN.V1_UP","description":"Genes up-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 [Gene ID=648] gene by RNAi."} {"geneset":"MEL18_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEL18_DN.V1_DN","description":"Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of PCGF2 [Gene ID=7703] gene by RNAi."} {"geneset":"MEL18_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/MEL18_DN.V1_UP","description":"Genes up-regulated in DAOY cells (medulloblastoma) upon knockdown of PCGF2 [Gene ID=7703] gene by RNAi."} {"geneset":"PTEN_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PTEN_DN.V1_DN","description":"Genes down-regulated upon knockdown of PTEN [Gene ID=5728] by RNAi."} {"geneset":"PTEN_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PTEN_DN.V1_UP","description":"Genes up-regulated upon knockdown of PTEN [Gene ID=5728] by RNAi."} {"geneset":"NOTCH_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOTCH_DN.V1_DN","description":"Genes down-regulated in MOLT4 cells (T-ALL) by DAPT [PubChem=16219261], an inhibitor of NOTCH signaling pathway."} {"geneset":"NOTCH_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NOTCH_DN.V1_UP","description":"Genes up-regulated in MOLT4 cells (T-ALL) by DAPT [PubChem=16219261], an inhibitor of NOTCH signaling pathway."} {"geneset":"EIF4E_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EIF4E_DN","description":"Genes down-regulated in HMEC cells (primary mammary epithelium) upon over-expression of EIF4E [Gene ID=1977] gene."} {"geneset":"EIF4E_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/EIF4E_UP","description":"Genes up-regulated in HMEC cells (primary mammary epithelium) upon over-expression of EIF4E [Gene ID=1977] gene."} {"geneset":"CRX_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CRX_DN.V1_DN","description":"Genes down-regulated in retina cells from CRX [Gene ID=1406] knockout mice."} {"geneset":"CRX_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CRX_DN.V1_UP","description":"Genes up-regulated in retina cells from CRX [Gene ID=1406] knockout mice."} {"geneset":"CRX_NRL_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CRX_NRL_DN.V1_DN","description":"Genes down-regulated in retina cells from CRX and NRL [Gene ID=1406, 4901] double knockout mice."} {"geneset":"CRX_NRL_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CRX_NRL_DN.V1_UP","description":"Genes up-regulated in retina cells from CRX and NRL [Gene ID=1406, 4901] double knockout mice."} {"geneset":"NRL_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NRL_DN.V1_DN","description":"Genes down-regulated in retina cells from NRL [Gene ID=4901] knockout mice."} {"geneset":"NRL_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NRL_DN.V1_UP","description":"Genes up-regulated in retina cells from NRL [Gene ID=4901] knockout mice."} {"geneset":"RB_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RB_DN.V1_DN","description":"Genes down-regulated in primary keratinocytes from RB1 [Gene ID=5925] skin specific knockout mice."} {"geneset":"RB_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RB_DN.V1_UP","description":"Genes up-regulated in primary keratinocytes from RB1 [Gene ID=5925] skin specific knockout mice."} {"geneset":"RB_P107_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RB_P107_DN.V1_DN","description":"Genes down-regulated in primary keratinocytes from RB1 and RBL1 [Gene ID=5925, 5933] skin specific knockout mice."} {"geneset":"RB_P107_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RB_P107_DN.V1_UP","description":"Genes up-regulated in primary keratinocytes from RB1 and RBL1 [Gene ID=5925, 5933] skin specific knockout mice."} {"geneset":"RB_P130_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RB_P130_DN.V1_DN","description":"Genes down-regulated in primary keratinocytes from RB1 and RBL2 [Gene ID=5925, 5934] skin specific knockout mice."} {"geneset":"RB_P130_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RB_P130_DN.V1_UP","description":"Genes up-regulated in primary keratinocytes from RB1 and RBL2 [Gene ID=5925, 5934] skin specific knockout mice."} {"geneset":"CAHOY_ASTROCYTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAHOY_ASTROCYTIC","description":"Genes up-regulated in astrocytes."} {"geneset":"CAHOY_ASTROGLIAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAHOY_ASTROGLIAL","description":"Genes up-regulated in astrogia cells."} {"geneset":"CAHOY_NEURONAL","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAHOY_NEURONAL","description":"Genes up-regulated in neurons."} {"geneset":"CAHOY_OLIGODENDROCUTIC","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CAHOY_OLIGODENDROCUTIC","description":"Genes up-regulated in oligodendrocytes."} {"geneset":"RPS14_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RPS14_DN.V1_DN","description":"Genes down-regulated in CD34+ hematopoietic progenitor cells after knockdown of RPS14 [Gene ID=6208] by RNAi."} {"geneset":"RPS14_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/RPS14_DN.V1_UP","description":"Genes up-regulated in CD34+ hematopoietic progenitor cells after knockdown of RPS14 [Gene ID=6208] by RNAi."} {"geneset":"IL15_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IL15_UP.V1_DN","description":"Genes down-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL15 [Gene ID=3600]."} {"geneset":"IL15_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IL15_UP.V1_UP","description":"Genes up-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL15 [Gene ID=3600]."} {"geneset":"IL2_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IL2_UP.V1_DN","description":"Genes down-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL2 [Gene ID=3558]."} {"geneset":"IL2_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IL2_UP.V1_UP","description":"Genes up-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL2 [Gene ID=3558]."} {"geneset":"IL21_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IL21_UP.V1_DN","description":"Genes down-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL21 [Gene ID=59067]."} {"geneset":"IL21_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/IL21_UP.V1_UP","description":"Genes up-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL21 [Gene ID=59067]."} {"geneset":"PDGF_ERK_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PDGF_ERK_DN.V1_DN","description":"Genes down-regulated in SH-SY5Y cells (neuroblastoma) in response to PDGF [Gene ID=] stimulation after pre-treatment with the ERK inhibitors U0126 and PD98059 [PubChem=3006531, 4713]."} {"geneset":"PDGF_ERK_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PDGF_ERK_DN.V1_UP","description":"Genes up-regulated in SH-SY5Y cells (neuroblastoma) in response to PDGF [Gene ID=] stimulation after pre-treatment with the ERK inhibitors U0126 and PD98059 [PubChem=3006531, 4713]."} {"geneset":"PDGF_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PDGF_UP.V1_DN","description":"Genes down-regulated in SH-SY5Y cells (neuroblastoma) in response to PDGF [Gene ID=] stimulation."} {"geneset":"PDGF_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/PDGF_UP.V1_UP","description":"Genes up-regulated in SH-SY5Y cells (neuroblastoma) in response to PDGF [Gene ID=] stimulation."} {"geneset":"TGFB_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGFB_UP.V1_DN","description":"Genes down-regulated in a panel of epithelial cell lines by TGFB1 [Gene ID=7040]."} {"geneset":"TGFB_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TGFB_UP.V1_UP","description":"Genes up-regulated in a panel of epithelial cell lines by TGFB1 [Gene ID=7040]."} {"geneset":"YAP1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAP1_DN","description":"Genes down-regulated in MCF10A cells (breast cancer) over-expressing YAP1 [Gene ID=10413] gene."} {"geneset":"YAP1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/YAP1_UP","description":"Genes up-regulated in MCF10A cells (breast cancer) over-expressing YAP1 [Gene ID=10413] gene."} {"geneset":"SIRNA_EIF4GI_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIRNA_EIF4GI_DN","description":"Genes down-regulated in MCF10A cells vs knockdown of EIF4G1 [Gene ID=1981] gene by RNAi."} {"geneset":"SIRNA_EIF4GI_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SIRNA_EIF4GI_UP","description":"Genes up-regulated in MCF10A cells vs knockdown of EIF4G1 [Gene ID=1981] gene by RNAi."} {"geneset":"HOXA9_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOXA9_DN.V1_DN","description":"Genes down-regulated in MOLM-14 cells (AML) with knockdown of HOXA9 [Gene ID=3205] gene by RNAi vs controls."} {"geneset":"HOXA9_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/HOXA9_DN.V1_UP","description":"Genes up-regulated in MOLM-14 cells (AML) with knockdown of HOXA9 [Gene ID=3205] gene by RNAi vs controls."} {"geneset":"SINGH_KRAS_DEPENDENCY_SIGNATURE_","url":"http://www.broadinstitute.org/gsea/msigdb/cards/SINGH_KRAS_DEPENDENCY_SIGNATURE_","description":"Genes defining the KRAS [Gene ID=3845] dependency signature."} {"geneset":"STK33_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STK33_DN","description":"Genes down-regulated in NOMO-1 and SKM-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi."} {"geneset":"STK33_NOMO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STK33_NOMO_DN","description":"Genes down-regulated in NOMO-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi."} {"geneset":"STK33_NOMO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STK33_NOMO_UP","description":"Genes up-regulated in NOMO-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi."} {"geneset":"STK33_SKM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STK33_SKM_DN","description":"Genes down-regulated in SKM-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi."} {"geneset":"STK33_SKM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STK33_SKM_UP","description":"Genes up-regulated in SKM-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi."} {"geneset":"STK33_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/STK33_UP","description":"Genes up-regulated in NOMO-1 and SKM-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi."} {"geneset":"KRAS.AMP.LUNG_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.AMP.LUNG_UP.V1_DN","description":"Genes down-regulated in epithelial lung cancer cell lines over-expressing KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.AMP.LUNG_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.AMP.LUNG_UP.V1_UP","description":"Genes up-regulated in epithelial lung cancer cell lines over-expressing KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.DF.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.DF.V1_DN","description":"Genes down-regulated in epithelial lung cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.DF.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.DF.V1_UP","description":"Genes up-regulated in epithelial lung cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"TBK1.DF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TBK1.DF_DN","description":"Genes down-regulated in epithelial lung cancer cell lines upon over-expression of an oncogenic form of KRAS [Gene ID=3845] gene and knockdown of TBK1 [Gene ID=29110] gene by RNAi."} {"geneset":"TBK1.DF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TBK1.DF_UP","description":"Genes up-regulated in epithelial lung cancer cell lines upon over-expression of an oncogenic form of KRAS [Gene ID=3845] gene and knockdown of TBK1 [Gene ID=29110] gene by RNAi."} {"geneset":"TBK1.DN.48HRS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TBK1.DN.48HRS_DN","description":"Genes down-regulated in epithelial lung cancer cell lines upon over-expression of an oncogenic form of KRAS [Gene ID=3845] gene and knockdown of TBK1 [Gene ID=29110] gene by RNAi."} {"geneset":"TBK1.DN.48HRS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/TBK1.DN.48HRS_UP","description":"Genes up-regulated in epithelial lung cancer cell lines upon over-expression of an oncogenic form of KRAS [Gene ID=3845] gene and knockdown of TBK1 [Gene ID=29110] gene by RNAi."} {"geneset":"NFE2L2.V2","url":"http://www.broadinstitute.org/gsea/msigdb/cards/NFE2L2.V2","description":"Genes up-regulated in MEF cells (embryonic fibroblasts) with knockout of NFE2L2 [Gene ID=4780] gene."} {"geneset":"CORDENONSI_YAP_CONSERVED_SIGNATURE","url":"http://www.broadinstitute.org/gsea/msigdb/cards/CORDENONSI_YAP_CONSERVED_SIGNATURE","description":"YAP conserved signature."} {"geneset":"JAK2_DN.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAK2_DN.V1_DN","description":"Genes down-regulated in HEL cells (erythroleukemia) after knockdown of JAK2 [Gene ID=3717] gene by RNAi."} {"geneset":"JAK2_DN.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/JAK2_DN.V1_UP","description":"Genes up-regulated in HEL cells (erythroleukemia) after knockdown of JAK2 [Gene ID=3717] gene by RNAi."} {"geneset":"KRAS.300_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.300_UP.V1_DN","description":"Genes down-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.300_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.300_UP.V1_UP","description":"Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.50_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.50_UP.V1_DN","description":"Genes down-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.50_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.50_UP.V1_UP","description":"Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.600_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.600_UP.V1_DN","description":"Genes down-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.600_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.600_UP.V1_UP","description":"Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.600.LUNG.BREAST_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.600.LUNG.BREAST_UP.V1_DN","description":"Genes down-regulated in epithelial lung and breast cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.600.LUNG.BREAST_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.600.LUNG.BREAST_UP.V1_UP","description":"Genes up-regulated in epithelial lung and breast cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.BREAST_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.BREAST_UP.V1_DN","description":"Genes down-regulated in epithelial breast cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.BREAST_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.BREAST_UP.V1_UP","description":"Genes up-regulated in epithelial breast cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.KIDNEY_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.KIDNEY_UP.V1_DN","description":"Genes down-regulated in epithelial kidney cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.KIDNEY_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.KIDNEY_UP.V1_UP","description":"Genes up-regulated in epithelial kidney cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.LUNG_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG_UP.V1_DN","description":"Genes down-regulated in epithelial lung cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.LUNG_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG_UP.V1_UP","description":"Genes up-regulated in epithelial lung cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.LUNG.BREAST_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG.BREAST_UP.V1_DN","description":"Genes down-regulated in epithelial breast cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845 gene]."} {"geneset":"KRAS.LUNG.BREAST_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG.BREAST_UP.V1_UP","description":"Genes up-regulated in epithelial lung and breast cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.PROSTATE_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.PROSTATE_UP.V1_DN","description":"Genes down-regulated in epithelial prostate cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"KRAS.PROSTATE_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.PROSTATE_UP.V1_UP","description":"Genes up-regulated in epithelial prostate cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene."} {"geneset":"LEF1_UP.V1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEF1_UP.V1_DN","description":"Genes down-regulated in DLD1 cells (colon carcinoma) over-expressing LEF1 [Gene ID=51176]."} {"geneset":"LEF1_UP.V1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/LEF1_UP.V1_UP","description":"Genes up-regulated in DLD1 cells (colon carcinoma) over-expressing LEF1 [Gene ID=51176]."} {"geneset":"KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve CD8 T cells compared to effector CD8 T cells at the peak expansion phase (day 8 after LCMV-Armstrong infection)."} {"geneset":"KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve CD8 T cells compared to effector CD8 T cells at the peak expansion phase (day 8 after LCMV-Armstrong infection)."} {"geneset":"KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve CD8 T cells compared to effector CD8 T cells at contraction phase (day 15 after LCMV-Armstrong infection)."} {"geneset":"KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve CD8 T cells compared to effector CD8 T cells at contraction phase (day 15 after LCMV-Armstrong infection)."} {"geneset":"KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve CD8 T cells compared to memory CD8 T cells (day 40+ after LCMV-Armstrong infection)."} {"geneset":"KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve CD8 T cells compared to memory CD8 T cells (day 40+ after LCMV-Armstrong infection)."} {"geneset":"KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP","description":"Genes up-regulated in effector CD8 T cells at the peak expansion phase (day 8 after LCMV-Armstrong infection) compared to effector CD8 T cells at contraction phase (day 15 after LCMV-Armstrong infection)."} {"geneset":"KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN","description":"Genes down-regulated in effector CD8 T cells at the peak expansion phase (day 8 after LCMV-Armstrong infection) compared to effector CD8 T cells at contraction phase (day 15 after LCMV-Armstrong infection)."} {"geneset":"KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in effector CD8 T cells at the peak expansion phase (day 8 after LCMV-Armstrong infection) compared to memory CD8 T cells (day 40+ after LCMV-Armstrong infection)."} {"geneset":"KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in effector CD8 T cells at the peak expansion phase (day 8 after LCMV-Armstrong infection) compared to memory CD8 T cells (day 40+ after LCMV-Armstrong infection)."} {"geneset":"KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in effector CD8 T cells at contraction phase (day 15 after LCMV-Armstrong infection) compared to memory CD8 T cells (day 40+ after LCMV-Armstrong infection)."} {"geneset":"KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in effector CD8 T cells at contraction phase (day 15 after LCMV-Armstrong infection) compared to memory CD8 T cells (day 40+ after LCMV-Armstrong infection)."} {"geneset":"GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naü¾™¦”¼ve CD8 T cells versus effector CD8 T cells."} {"geneset":"GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naü¾™¦”¼ve CD8 T cells versus effector CD8 T cells."} {"geneset":"GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells."} {"geneset":"GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus memory CD8 T cells."} {"geneset":"GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of effector CD8 T cells versus memory CD8 T cells."} {"geneset":"GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of effector CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells from mice challenged with LCMV versus those challenged with Listeria-gp61."} {"geneset":"GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells from mice challenged with LCMV versus those challenged with Listeria-gp61."} {"geneset":"GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 T cells KLRG1 Int [GeneID=10219]."} {"geneset":"GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus effector CD8 T cells KLRG1 Int [GeneID=10219]."} {"geneset":"GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 T cells KLRG1 high [GeneID=10219]."} {"geneset":"GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus effector CD8 T cells KLRG1 high [GeneID=10219]."} {"geneset":"GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells versus effector CD8 T cells KLRG1 intermediate [GeneID=10219]."} {"geneset":"GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells versus effector CD8 T cells KLRG1 intermediate [GeneID=10219]."} {"geneset":"GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells versus effector CD8 T cells KLRG1 high [GeneID=10219]."} {"geneset":"GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells versus effector CD8 T cells KLRG1 high [GeneID=10219]."} {"geneset":"GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of effector CD8 T cells KRLG1 Int [GeneID=10219] vs those with KRLG1 Hi."} {"geneset":"GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of effector CD8 T cells KRLG1 Int [GeneID=10219] vs those with KRLG1 Hi."} {"geneset":"GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive vs effector CD8 T cells (4-5 days postinfection)."} {"geneset":"GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive vs effector CD8 T cells (4-5 days postinfection)."} {"geneset":"GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells versus effector CD8 T cells."} {"geneset":"GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells versus effector CD8 T cells."} {"geneset":"GSE10325_CD4_TCELL_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_CD4_TCELL_VS_BCELL_UP","description":"Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy CD19 [GeneID=920] B cells."} {"geneset":"GSE10325_CD4_TCELL_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_CD4_TCELL_VS_BCELL_DN","description":"Genes down-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy CD19 [GeneID=920] B cells."} {"geneset":"GSE10325_CD4_TCELL_VS_MYELOID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_CD4_TCELL_VS_MYELOID_UP","description":"Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy myeloid cells."} {"geneset":"GSE10325_CD4_TCELL_VS_MYELOID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_CD4_TCELL_VS_MYELOID_DN","description":"Genes down-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy myeloid cells."} {"geneset":"GSE10325_BCELL_VS_MYELOID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_BCELL_VS_MYELOID_UP","description":"Genes up-regulated in comparison of healthy B cells versus healthy myeloid cells."} {"geneset":"GSE10325_BCELL_VS_MYELOID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_BCELL_VS_MYELOID_DN","description":"Genes down-regulated in comparison of healthy B cells versus healthy myeloid cells."} {"geneset":"GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP","description":"Genes up-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus B cells."} {"geneset":"GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN","description":"Genes down-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus B cells."} {"geneset":"GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP","description":"Genes up-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus myeloid cells."} {"geneset":"GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN","description":"Genes down-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus myeloid cells."} {"geneset":"GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_UP","description":"Genes up-regulated in comparison of systemic lupus erythematosus B cells versus systemic lupus erythromatosus myeloid cells."} {"geneset":"GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN","description":"Genes down-regulated in comparison of systemic lupus erythematosus B cells versus systemic lupus erythromatosus myeloid cells."} {"geneset":"GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_UP","description":"Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus systemic lupus erythematosus CD4 [GeneID=920] T cells."} {"geneset":"GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN","description":"Genes down-regulated in comparison of healthy CD4 [GeneID=920] T cells versus systemic lupus erythematosus CD4 [GeneID=920] T cells."} {"geneset":"GSE10325_BCELL_VS_LUPUS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_BCELL_VS_LUPUS_BCELL_UP","description":"Genes up-regulated in comparison of healthy B cells versus systemic lupus erythematosus B cells."} {"geneset":"GSE10325_BCELL_VS_LUPUS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_BCELL_VS_LUPUS_BCELL_DN","description":"Genes down-regulated in comparison of healthy B cells versus systemic lupus erythematosus B cells."} {"geneset":"GSE10325_MYELOID_VS_LUPUS_MYELOID_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_MYELOID_VS_LUPUS_MYELOID_UP","description":"Genes up-regulated in comparison of healthy myeloid cells versus systemic lupus erythematosus myeloid cells."} {"geneset":"GSE10325_MYELOID_VS_LUPUS_MYELOID_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10325_MYELOID_VS_LUPUS_MYELOID_DN","description":"Genes down-regulated in comparison of healthy myeloid cells versus systemic lupus erythematosus myeloid cells."} {"geneset":"GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_UP","description":"Genes up-regulated in comparison of dendritic cells activated in the absense of VAF347 [PubChem=10172275] versus those activated in the presence of VAF347 [PubChem=10172275]."} {"geneset":"GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_DN","description":"Genes down-regulated in comparison of dendritic cells activated in the absense of VAF347 [PubChem=10172275] versus those activated in the presence of VAF347 [PubChem=10172275]."} {"geneset":"GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP","description":"Genes up-regulated in comparison of macrophages treated with control (hIgG1) versus those treated with TNFRSF6B [GeneID=8771]."} {"geneset":"GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_DN","description":"Genes down-regulated in comparison of macrophages treated with control (hIgG1) versus those treated with TNFRSF6B [GeneID=8771]."} {"geneset":"GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of naive T cells versus effector memory T cells."} {"geneset":"GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of naive T cells versus effector memory T cells."} {"geneset":"GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of naive T cells versus central memory T cells."} {"geneset":"GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of naive T cells versus central memory T cells."} {"geneset":"GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP","description":"Genes up-regulated in comparison of naive T cells versus peripheral blood mononuclear cells (PBMC)."} {"geneset":"GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN","description":"Genes down-regulated in comparison of naive T cells versus peripheral blood mononuclear cells (PBMC)."} {"geneset":"GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP","description":"Genes up-regulated in comparison of effector memory T cells versus central memory T cells from peripheral blood mononuclear cells (PBMC)."} {"geneset":"GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN","description":"Genes down-regulated in comparison of effector memory T cells versus central memory T cells from peripheral blood mononuclear cells (PBMC)."} {"geneset":"GSE11057_CD4_EFF_MEM_VS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_CD4_EFF_MEM_VS_PBMC_UP","description":"Genes up-regulated in comparison of effector memory T cells versus peripheral blood mononuclear cells (PBMC)."} {"geneset":"GSE11057_CD4_EFF_MEM_VS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_CD4_EFF_MEM_VS_PBMC_DN","description":"Genes down-regulated in comarison of effector memory T cells versus peripheral blood mononuclear cells (PBMC)."} {"geneset":"GSE11057_CD4_CENT_MEM_VS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_CD4_CENT_MEM_VS_PBMC_UP","description":"Genes up-regulated in comparison of central memory T cells versus peripheral blood mononuclear cells (PBMC)."} {"geneset":"GSE11057_CD4_CENT_MEM_VS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_CD4_CENT_MEM_VS_PBMC_DN","description":"Genes down-regulated in comparison of central memory T cells versus peripheral blood mononuclear cells (PBMC)."} {"geneset":"GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of naive T cells versus memory T cells."} {"geneset":"GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of naive T cells versus memory T cells."} {"geneset":"GSE11057_PBMC_VS_MEM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_PBMC_VS_MEM_CD4_TCELL_UP","description":"Genes up-regulated in comparison of peripheral mononuclear blood cells (PBMC) versus memory T cells."} {"geneset":"GSE11057_PBMC_VS_MEM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11057_PBMC_VS_MEM_CD4_TCELL_DN","description":"Genes down-regulated in comparison of peripheral mononuclear blood cells (PBMC) versus memory T cells."} {"geneset":"GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP","description":"Genes up-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435]."} {"geneset":"GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN","description":"Genes down-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435]."} {"geneset":"GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP","description":"Genes up-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458]."} {"geneset":"GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN","description":"Genes down-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458]."} {"geneset":"GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP","description":"Genes up-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435] and Pam3Cys (TLR2 agonist)."} {"geneset":"GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN","description":"Genes down-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435] and Pam3Cys (TLR2 agonist)."} {"geneset":"GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP","description":"Genes up-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cys (TLR2 agonist)."} {"geneset":"GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN","description":"Genes down-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cys (TLR2 agonist)."} {"geneset":"GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP","description":"Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458]."} {"geneset":"GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_DN","description":"Genes down-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458]."} {"geneset":"GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP","description":"Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435] and Pam3Cyc."} {"geneset":"GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN","description":"Genes down-regulated in comparison of macrophages cultured with M-CSF[GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435] and Pam3Cyc."} {"geneset":"GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP","description":"Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cyc."} {"geneset":"GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN","description":"Genes down-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cyc."} {"geneset":"GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP","description":"Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458] versus macrophages cultured with M-CSF [GeneID=1435] and Pam3Cyc."} {"geneset":"GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN","description":"Genes down-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458] versus macrophages cultured with M-CSF [GeneID=1435] and Pam3Cyc."} {"geneset":"GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP","description":"Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458] versus macrophages cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cys (TLR2 agonist)."} {"geneset":"GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN","description":"Genes down-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458] versus macrophages cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cys (TLR2 agonist)."} {"geneset":"GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP","description":"Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] and Pam3Cyc versus macrophages cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cyc."} {"geneset":"GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN","description":"Genes down-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] and Pam3Cyc versus macrophages cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cyc."} {"geneset":"GSE11924_TFH_VS_TH1_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TFH_VS_TH1_CD4_TCELL_UP","description":"Genes up-regulated in comparison of T follicular helper (Tfh) cells versus Th1 cells."} {"geneset":"GSE11924_TFH_VS_TH1_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TFH_VS_TH1_CD4_TCELL_DN","description":"Genes down-regulated in comparison of T follicular helper (Tfh) cells versus Th1 cells."} {"geneset":"GSE11924_TFH_VS_TH2_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TFH_VS_TH2_CD4_TCELL_UP","description":"Genes up-regulated in comparison of T follicular helper (Tfh) cells versus Th2 cells."} {"geneset":"GSE11924_TFH_VS_TH2_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TFH_VS_TH2_CD4_TCELL_DN","description":"Genes down-regulated in comparison of T follicular helper (Tfh) cells versus Th2 cells."} {"geneset":"GSE11924_TFH_VS_TH17_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TFH_VS_TH17_CD4_TCELL_UP","description":"Genes up-regulated in comparison of T follicular helper (Tfh) cells versus Th17 cells."} {"geneset":"GSE11924_TFH_VS_TH17_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TFH_VS_TH17_CD4_TCELL_DN","description":"Genes down-regulated in comparison of T follicular helper (Tfh) cells versus Th17 cells."} {"geneset":"GSE11924_TH1_VS_TH2_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TH1_VS_TH2_CD4_TCELL_UP","description":"Genes up-regulated in comparison of Th1 cells versus Th2 cells."} {"geneset":"GSE11924_TH1_VS_TH2_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TH1_VS_TH2_CD4_TCELL_DN","description":"Genes down-regulated in comparison of Th1 cells versus Th2 cells."} {"geneset":"GSE11924_TH1_VS_TH17_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TH1_VS_TH17_CD4_TCELL_UP","description":"Genes up-regulated in comparison of Th1 cells versus Th17 cells."} {"geneset":"GSE11924_TH1_VS_TH17_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TH1_VS_TH17_CD4_TCELL_DN","description":"Genes down-regulated in comparison of Th1 cells versus Th17 cells."} {"geneset":"GSE11924_TH2_VS_TH17_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TH2_VS_TH17_CD4_TCELL_UP","description":"Genes up-regulated in comparison of Th2 cells versus Th17 cells."} {"geneset":"GSE11924_TH2_VS_TH17_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11924_TH2_VS_TH17_CD4_TCELL_DN","description":"Genes down-regulated in comparison of Th2 cells versus Th17 cells."} {"geneset":"GSE12366_GC_BCELL_VS_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_GC_BCELL_VS_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of germinal center B cells versus plasma cells."} {"geneset":"GSE12366_GC_BCELL_VS_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_GC_BCELL_VS_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of germinal center B cells versus plasma cells."} {"geneset":"GSE12366_GC_VS_NAIVE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_GC_VS_NAIVE_BCELL_UP","description":"Genes up-regulated in comparison of germinal center B cells versus naive B cells."} {"geneset":"GSE12366_GC_VS_NAIVE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_GC_VS_NAIVE_BCELL_DN","description":"Genes down-regulated in comparison of germinal center B cells versus naive B cells."} {"geneset":"GSE12366_GC_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_GC_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of germinal center B cells versus memory B cells."} {"geneset":"GSE12366_GC_VS_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_GC_VS_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of germinal center B cells versus memory B cells."} {"geneset":"GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_UP","description":"Genes up-regulated in plasma cells versus naive B cells."} {"geneset":"GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN","description":"Genes down-regulated in plasma cells versus naive B cells."} {"geneset":"GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in plasma cells versus memory B cells."} {"geneset":"GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN","description":"Genes down-regulated in plasma cells versus memory B cells."} {"geneset":"GSE12366_NAIVE_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_NAIVE_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of naive B cells versus memory B cells."} {"geneset":"GSE12366_NAIVE_VS_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12366_NAIVE_VS_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of naive B cells versus memory B cells."} {"geneset":"GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP","description":"Genes up-regulated in comparison of IgD+ B cells versus IgD- B cells."} {"geneset":"GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN","description":"Genes down-regulated in comparison of IgD+ B cells versus IgD- B cells."} {"geneset":"GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of IgD+ peripheral blood B cells versus IgD- naive tonsil B cells."} {"geneset":"GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of IgD+ peripheral blood B cells versus IgD- naive tonsil B cells."} {"geneset":"GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of IgD+ B cells from peripheral blood versus CD19 pre-germinal center tonsil B cell"} {"geneset":"GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of IgD+ B cells from peripheral blood versus CD19 pre-germinal center tonsil B cell"} {"geneset":"GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of IgD+ peripheral blood B cells versus dark zone germincal center B cells."} {"geneset":"GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of IgD+ peripheral blood B cells versus dark zone germincal center B cells."} {"geneset":"GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of IgD- peripheral blood B cells versus dark zone germinal center B cells."} {"geneset":"GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of IgD- peripheral blood B cells versus dark zone germinal center B cells."} {"geneset":"GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of IgD- peripheral blood B cells versus pre-germinal center B cells."} {"geneset":"GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of IgD- peripheral blood B cells versus pre-germinal center B cells."} {"geneset":"GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of IgD- peripheral blood B cells versus dark zone germinal center B cells."} {"geneset":"GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of IgD- peripheral blood B cells versus dark zone germinal center B cells."} {"geneset":"GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of naive B cell versus pre-germinal tonsil B cells."} {"geneset":"GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of naive B cell versus pre-germinal tonsil B cells."} {"geneset":"GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of naive B cell versus dark zone germinal center B cells."} {"geneset":"GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of naive B cell versus dark zone germinal center B cells."} {"geneset":"GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP","description":"Genes up-regulated in comparison of pre-germinal center B cells versus dark zone germinal center B cells."} {"geneset":"GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN","description":"Genes down-regulated in comparison of pre-germinal center B cells versus dark zone germinal center B cells."} {"geneset":"GSE13229_IMM_VS_MATURE_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13229_IMM_VS_MATURE_NKCELL_UP","description":"Genes up-regulated in comparison of immature NK cells versus mature NK cells."} {"geneset":"GSE13229_IMM_VS_MATURE_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13229_IMM_VS_MATURE_NKCELL_DN","description":"Genes down-regulated in comparison of immature NK cells versus mature NK cells."} {"geneset":"GSE13229_IMM_VS_INTMATURE_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13229_IMM_VS_INTMATURE_NKCELL_UP","description":"Genes up-regulated in comparison of immature NK cells versus intermediate mature NK cells."} {"geneset":"GSE13229_IMM_VS_INTMATURE_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13229_IMM_VS_INTMATURE_NKCELL_DN","description":"Genes down-regulated in comparison of immature NK cells versus intermediate mature NK cells."} {"geneset":"GSE13229_MATURE_VS_INTMATURE_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13229_MATURE_VS_INTMATURE_NKCELL_UP","description":"Genes up-regulated in comparison of mature NK cells versus intermediate mature KN cells."} {"geneset":"GSE13229_MATURE_VS_INTMATURE_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13229_MATURE_VS_INTMATURE_NKCELL_DN","description":"Genes down-regulated in comparison of mature NK cells versus intermediate mature KN cells."} {"geneset":"GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells activated with lamina propria dendritic cells versus regulatory T cell (Treg)."} {"geneset":"GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells activated with lamina propria dendritic cells versus regulatory T cell (Treg)."} {"geneset":"GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) versus conventional T cells activated with lamina propria dendritic cells."} {"geneset":"GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) versus conventional T cells activated with lamina propria dendritic cells."} {"geneset":"GSE13306_TREG_VS_TCONV_SPLEEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_TREG_VS_TCONV_SPLEEN_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) versus conventional T cells."} {"geneset":"GSE13306_TREG_VS_TCONV_SPLEEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_TREG_VS_TCONV_SPLEEN_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) versus conventional T cells."} {"geneset":"GSE13306_TREG_RA_VS_TCONV_RA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_TREG_RA_VS_TCONV_RA_UP","description":"Genes up-regulated in regulatory T cell (Treg) treated with retinoic acid (tretinoin) [PubChem=444795] versus conventional T cells."} {"geneset":"GSE13306_TREG_RA_VS_TCONV_RA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_TREG_RA_VS_TCONV_RA_DN","description":"Genes down-regulated in regulatory T cell (Treg) treated with retinoic acid (tretinoin) [PubChem=444795] versus conventional T cells."} {"geneset":"GSE13306_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_TREG_VS_TCONV_UP","description":"Genes up-regulated in regulatory T cell (Treg) versus conventional T cells."} {"geneset":"GSE13306_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_TREG_VS_TCONV_DN","description":"Genes down-regulated in regulatory T cell (Treg) versus conventional T cells."} {"geneset":"GSE13306_RA_VS_UNTREATED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_RA_VS_UNTREATED_TREG_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated regulatory T cell (Treg)."} {"geneset":"GSE13306_RA_VS_UNTREATED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_RA_VS_UNTREATED_TREG_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated regulatory T cell (Treg)."} {"geneset":"GSE13306_RA_VS_UNTREATED_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_RA_VS_UNTREATED_TCONV_UP","description":"Genes up-regulated in comparison of conventional T cells treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated conventional T cells."} {"geneset":"GSE13306_RA_VS_UNTREATED_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_RA_VS_UNTREATED_TCONV_DN","description":"Genes down-regulated in comparison of conventional T cells treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated conventional T cells."} {"geneset":"GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP","description":"Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated memory CD4 [GeneID=920] T cells."} {"geneset":"GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN","description":"Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated memory CD4 [GeneID=920] T cells."} {"geneset":"GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of naive B cells versus IgM-memory B cells."} {"geneset":"GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of naive B cells versus IgM-memory B cells."} {"geneset":"GSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of naive B cells versus Ig isotype switched memory B cells."} {"geneset":"GSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of naive B cells versus Ig isotype switched memory B cells."} {"geneset":"GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of naive B cells versus plasma cells."} {"geneset":"GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of naive B cells versus plasma cells."} {"geneset":"GSE13411_NAIVE_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_NAIVE_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of naive B cells versus memory B cells."} {"geneset":"GSE13411_NAIVE_VS_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_NAIVE_VS_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of naive B cells versus memory B cells."} {"geneset":"GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of IgM-memory B cells versus Ig isotype switched memory B cells."} {"geneset":"GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of IgM-memory B cells versus Ig isotype switched memory B cells."} {"geneset":"GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of IgM-memory B cells versus plasma cells."} {"geneset":"GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of IgM-memory B cells versus plasma cells."} {"geneset":"GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of Ig isotype switched memory B cells versus plasma cells."} {"geneset":"GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of Ig isotype switched memory B cells versus plasma cells."} {"geneset":"GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of plasma cells versus memory B cells."} {"geneset":"GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of plasma cells versus memory B cells."} {"geneset":"GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 0 h versus PBMC cultured for 3 h with YF17D vaccine."} {"geneset":"GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 0 h versus PBMC cultured for 3 h with YF17D vaccine."} {"geneset":"GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 0 h versus PBMC cultured for 12 h with YF17D vaccine."} {"geneset":"GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 0 h versus PBMC cultured for 12 h with YF17D vaccine."} {"geneset":"GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 3 h versus PBMC cultured for 3 h with YF17D vaccine."} {"geneset":"GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 3 h versus PBMC cultured for 3 h with YF17D vaccine."} {"geneset":"GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 12 h versus PBMC cultured for 12 h with YF17D vaccine."} {"geneset":"GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 12 h versus PBMC cultured for 12 h with YF17D vaccine."} {"geneset":"GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) cultured with YF17D vaccine for 12 h versus PBMC cultured for 3 h."} {"geneset":"GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) cultured with YF17D vaccine for 12 h versus PBMC cultured for 3 h."} {"geneset":"GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC stimulated with YF17D vaccine."} {"geneset":"GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC stimulated with YF17D vaccine."} {"geneset":"GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 1 day after stimulation with YF17D vaccine."} {"geneset":"GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 1 day after stimulation with YF17D vaccine."} {"geneset":"GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 3 days after stimulation with YF17D vaccine."} {"geneset":"GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 3 days after stimulation with YF17D vaccine."} {"geneset":"GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 7 days after stimulation with YF17D vaccine."} {"geneset":"GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 7 days after stimulation with YF17D vaccine."} {"geneset":"GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 21 days after stimulation with YF17D vaccine."} {"geneset":"GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 21 days after stimulation with YF17D vaccine."} {"geneset":"GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 1 day after stimulation with YF17D vaccine versus PBMC 3 days after the stimulation."} {"geneset":"GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 1 day after stimulation with YF17D vaccine versus PBMC 3 days after the stimulation."} {"geneset":"GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 1 day after stimulation with YF17D vaccine versus PBMC 7 days after the stimulation."} {"geneset":"GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 1 day after stimulation with YF17D vaccine versus PBMC 7 days after the stimulation."} {"geneset":"GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 1 day after stimulation with YF17D vaccine versus PBMC 21 days after the stimulation."} {"geneset":"GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 1 day after stimulation with YF17D vaccine versus PBMC 21 days after the stimulation."} {"geneset":"GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 3 days after stimulation with YF17D vaccine versus PBMC 7 days after the stimulation."} {"geneset":"GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 3 days after stimulation with YF17D vaccine versus PBMC 7 days after the stimulation."} {"geneset":"GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 3 days after stimulation with YF17D vaccine versus PBMC 21 days after the stimulation."} {"geneset":"GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 3 days after stimulation with YF17D vaccine versus PBMC 21 days after the stimulation."} {"geneset":"GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 7 days after stimulation with YF17D vaccine versus PBMC 21 days after the stimulation."} {"geneset":"GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 7 days after stimulation with YF17D vaccine versus PBMC 21 days after the stimulation."} {"geneset":"GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) before vs after YF17D vaccination."} {"geneset":"GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) before vs after YF17D vaccination."} {"geneset":"GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus CD4 [GeneID=920] Int CD8 thymocytes."} {"geneset":"GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus CD4 [GeneID=920] Int CD8 thymocytes."} {"geneset":"GSE13493_DP_VS_CD8POS_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13493_DP_VS_CD8POS_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus CD8 thymocytes."} {"geneset":"GSE13493_DP_VS_CD8POS_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13493_DP_VS_CD8POS_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus CD8 thymocytes."} {"geneset":"GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] CD8 Int thymocytes versus CD8 thymocytes."} {"geneset":"GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] CD8 Int thymocytes versus CD8 thymocytes."} {"geneset":"GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in comparison of resting CD4 [GeneID=920] T cells versus directly activated CD4 [GeneID=920] T cells."} {"geneset":"GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in comparison of resting CD4 [GeneID=920] T cells versus directly activated CD4 [GeneID=920] T cells."} {"geneset":"GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in comparison of resting CD4 [GeneID=920] T cells versus bystander activated CD4 [GeneID=920] T cells."} {"geneset":"GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in comparison of resting CD4 [GeneID=920] T cells versus bystander activated CD4 [GeneID=920] T cells."} {"geneset":"GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in comparison of directly activated CD4 [GeneID=920] T cells versus bystander activated CD4 [GeneID=920] T cells."} {"geneset":"GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in comparison of directly activated CD4 [GeneID=920] T cells versus bystander activated CD4 [GeneID=920] T cells."} {"geneset":"GSE14000_TRANSLATED_RNA_VS_MRNA_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_TRANSLATED_RNA_VS_MRNA_DC_UP","description":"Genes up-regulated in comparison of polysome bound (translated) mRNA versus total mRNA in dendritic cells."} {"geneset":"GSE14000_TRANSLATED_RNA_VS_MRNA_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_TRANSLATED_RNA_VS_MRNA_DC_DN","description":"Genes down-regulated in comparison of polysome bound (translated) mRNA versus total mRNA in dendritic cells."} {"geneset":"GSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_UP","description":"Genes up-regulated in comparison of polysome bound (translated) mRNA versus total mRNA 4 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_DN","description":"Genes down-regulated in comparison of polysome bound (translated) mRNA versus total mRNA 4 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_TRANSLATED_RNA_VS_MRNA_16H_LPS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_TRANSLATED_RNA_VS_MRNA_16H_LPS_DC_UP","description":"Genes up-regulated in comparison of polysome bound (translated) mRNA versus total mRNA 16 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_TRANSLATED_RNA_VS_MRNA_16H_LPS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_TRANSLATED_RNA_VS_MRNA_16H_LPS_DC_DN","description":"Genes down-regulated in comparison of polysome bound (translated) mRNA versus total mRNA 16 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_UP","description":"Genes up-regulated in comparison of polysome bound (translated) mRNA before and 4 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN","description":"Genes down-regulated in comparison of polysome bound (translated) mRNA before and 4 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_UP","description":"Genes up-regulated in comparison of polysome bound (translated) mRNA before and 16 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN","description":"Genes down-regulated in comparison of polysome bound (translated) mRNA before and 16 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_UNSTIM_VS_4H_LPS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_UNSTIM_VS_4H_LPS_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) before and 4 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_UNSTIM_VS_4H_LPS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_UNSTIM_VS_4H_LPS_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) before and 4 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_UNSTIM_VS_16H_LPS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_UNSTIM_VS_16H_LPS_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) before and 16 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_UNSTIM_VS_16H_LPS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_UNSTIM_VS_16H_LPS_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) before and 16 h after LPS (TLR4 agonist) stimulation."} {"geneset":"GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP","description":"Genes up-regulated in comparison of polysome bound (translated) mRNA in dendritic cells (DC) at 4 h after LPS (TLR4 agonist) stimulation versus those at 16 h after the stimulation."} {"geneset":"GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN","description":"Genes down-regulated in comparison of polysome bound (translated) mRNA in dendritic cells (DC) at 4 h after LPS (TLR4 agonist) stimulation versus those at 16 h after the stimulation."} {"geneset":"GSE14000_4H_VS_16H_LPS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_4H_VS_16H_LPS_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) at 4 h after LPS (TLR4 agonist) stimulation versus those at 16 h after the stimulation."} {"geneset":"GSE14000_4H_VS_16H_LPS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14000_4H_VS_16H_LPS_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) at 4 h after LPS (TLR4 agonist) stimulation versus those at 16 h after the stimulation."} {"geneset":"GSE14026_TH1_VS_TH17_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14026_TH1_VS_TH17_UP","description":"Genes up-regulated in comparison of Th1 cells versus Th17 cells."} {"geneset":"GSE14026_TH1_VS_TH17_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14026_TH1_VS_TH17_DN","description":"Genes down-regulated in comparison of Th1 cells versus Th17 cells."} {"geneset":"GSE14308_TH2_VS_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_TH1_UP","description":"Genes up-regulated in comparison of Th2 cells versus Th1 cells."} {"geneset":"GSE14308_TH2_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_TH1_DN","description":"Genes down-regulated in comparison of Th2 cells versus Th1 cells."} {"geneset":"GSE14308_TH2_VS_TH17_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_TH17_UP","description":"Genes up-regulated in comparison of Th2 cells versus Th17 cells."} {"geneset":"GSE14308_TH2_VS_TH17_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_TH17_DN","description":"Genes down-regulated in comparison of Th2 cells versus Th17 cells."} {"geneset":"GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in comparison of Th2 cells versus naive CD4 [GeneID=620] T cells."} {"geneset":"GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in comparison of Th2 cells versus naive CD4 [GeneID=620] T cells."} {"geneset":"GSE14308_TH2_VS_INDUCED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_INDUCED_TREG_UP","description":"Genes up-regulated in comparison of Th2cells versus induced regulatory T cell (Treg)."} {"geneset":"GSE14308_TH2_VS_INDUCED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_INDUCED_TREG_DN","description":"Genes down-regulated in comparison of Th2 cells versus induced regulatory T cell (Treg)."} {"geneset":"GSE14308_TH2_VS_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_NATURAL_TREG_UP","description":"Genes up-regulated in comparison of Th2 cells versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_TH2_VS_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH2_VS_NATURAL_TREG_DN","description":"Genes down-regulated in comparison of Th2 cells versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_TH1_VS_TH17_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH1_VS_TH17_UP","description":"Genes up-regulated in comparison of Th1 cells versus Th17 cells."} {"geneset":"GSE14308_TH1_VS_TH17_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH1_VS_TH17_DN","description":"Genes down-regulated in comparison of Th1 cells versus Th17 cells."} {"geneset":"GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in comparison of Th1 cells versus naive CD4 [GeneID=920] T cells."} {"geneset":"GSE14308_TH1_VS_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH1_VS_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in comparison of Th1 cells versus naive CD4 [GeneID=920] T cells."} {"geneset":"GSE14308_TH1_VS_INDUCED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH1_VS_INDUCED_TREG_UP","description":"Genes up-regulated in comparison of Th1 cells versus induced regulatory T cell (Treg)."} {"geneset":"GSE14308_TH1_VS_INDUCED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH1_VS_INDUCED_TREG_DN","description":"Genes down-regulated in comparison of Th1 cells versus induced regulatory T cell (Treg)."} {"geneset":"GSE14308_TH1_VS_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH1_VS_NATURAL_TREG_UP","description":"Genes up-regulated in comparison of Th1 cells versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_TH1_VS_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH1_VS_NATURAL_TREG_DN","description":"Genes down-regulated in comparison of Th1 cells versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in comparison of Th17 cells versus naive CD4 [GeneID=920] T cells."} {"geneset":"GSE14308_TH17_VS_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH17_VS_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in comparison of Th17 cells versus naive CD4 [GeneID=920] T cells."} {"geneset":"GSE14308_TH17_VS_INDUCED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH17_VS_INDUCED_TREG_UP","description":"Genes up-regulated in comparison of Th17 cells versus induced regulatory T cell (Treg)."} {"geneset":"GSE14308_TH17_VS_INDUCED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH17_VS_INDUCED_TREG_DN","description":"Genes down-regulated in comparison of Th17 cells versus induced regulatory T cell (Treg)."} {"geneset":"GSE14308_TH17_VS_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH17_VS_NATURAL_TREG_UP","description":"Genes up-regulated in comparison of Th17 cells versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_TH17_VS_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_TH17_VS_NATURAL_TREG_DN","description":"Genes down-regulated in comparison of Th17 cells versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus induced regulatory T cell (Treg)."} {"geneset":"GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus induced regulatory T cell (Treg)."} {"geneset":"GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_INDUCED_VS_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_INDUCED_VS_NATURAL_TREG_UP","description":"Genes up-regulated in comparison of induced regulatory T cell (Treg) versus natural regulatory T cell (Treg)."} {"geneset":"GSE14308_INDUCED_VS_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14308_INDUCED_VS_NATURAL_TREG_DN","description":"Genes down-regulated in comparison of induced regulatory T cell (Treg) versus natural regulatory T cell (Treg)."} {"geneset":"GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP","description":"Genes up-regulated in comparison of control microglia cells versus those 1 h after stimulation with IFNG [GeneID=3458]."} {"geneset":"GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_DN","description":"Genes down-regulated in comparison of control microglia cells versus those 1 h after stimulation with IFNG [GeneID=3458]."} {"geneset":"GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP","description":"Genes up-regulated in comparison of control microglia cells versus those 6 h after stimulation with IFNG [GeneID=3458]."} {"geneset":"GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN","description":"Genes down-regulated in comparison of control microglia cells versus those 6 h after stimulation with IFNG [GeneID=3458]."} {"geneset":"GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP","description":"Genes up-regulated in comparison of control microglia cells versus those 24 h after stimulation with IFNG [GeneID=3458]."} {"geneset":"GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN","description":"Genes down-regulated in comparison of control microglia cells versus those 24 h after stimulation with IFNG [GeneID=3458]."} {"geneset":"GSE1432_1H_VS_6H_IFNG_MICROGLIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_1H_VS_6H_IFNG_MICROGLIA_UP","description":"Genes up-regulated in comparison of microglia cells 1 h after stimulation with IFNG [GeneID=3458] versus microglia cells 6 h after the stimulation."} {"geneset":"GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN","description":"Genes down-regulated in comparison of microglia cells 1 h after stimulation with IFNG [GeneID=3458] versus microglia cells 6 h after the stimulation."} {"geneset":"GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP","description":"Genes up-regulated in comparison of microglia cells 1 h after stimulation with IFNG [GeneID=3458] versus microglia cells 24 h after the stimulation."} {"geneset":"GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN","description":"Genes down-regulated in comparison of microglia cells 1 h after stimulation with IFNG [GeneID=3458] versus microglia cells 24 h after the stimulation."} {"geneset":"GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP","description":"Genes up-regulated in comparison of microglia cells 6 h after stimulation with IFNG [GeneID=3458] versus microglia cells 24 h after the stimulation."} {"geneset":"GSE1432_6H_VS_24H_IFNG_MICROGLIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1432_6H_VS_24H_IFNG_MICROGLIA_DN","description":"Genes down-regulated in comparison of microglia cells 6 h after stimulation with IFNG [GeneID=3458] versus microglia cells 24 h after the stimulation."} {"geneset":"GSE14350_TREG_VS_TEFF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14350_TREG_VS_TEFF_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) versus effector T cells."} {"geneset":"GSE14350_TREG_VS_TEFF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14350_TREG_VS_TEFF_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) versus effector T cells."} {"geneset":"GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) from IL2RB [GeneID=3560] defficient mice versus effector T cells from IL2RB [GeneID=3560] defficient mice."} {"geneset":"GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) from IL2RB [GeneID=3560] defficient mice versus effector T cells from IL2RB [GeneID=3560] defficient mice."} {"geneset":"GSE14350_IL2RB_KO_VS_WT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14350_IL2RB_KO_VS_WT_TREG_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) from IL2RB [GeneID=3560] defficient mice versus regulatory T cell (Treg) from wild type animals."} {"geneset":"GSE14350_IL2RB_KO_VS_WT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14350_IL2RB_KO_VS_WT_TREG_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) from IL2RB [GeneID=3560] defficient mice versus regulatory T cell (Treg) from wild type animals."} {"geneset":"GSE14350_IL2RB_KO_VS_WT_TEFF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14350_IL2RB_KO_VS_WT_TEFF_UP","description":"Genes up-regulated in comparison of effector T cells from IL2RB [GeneID=3560] defficient mice versus effector T cells from wild type animals."} {"geneset":"GSE14350_IL2RB_KO_VS_WT_TEFF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14350_IL2RB_KO_VS_WT_TEFF_DN","description":"Genes down-regulated in comparison of effector T cells from IL2RB [GeneID=3560] defficient mice versus effector T cells from wild type animals."} {"geneset":"GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of control CD4 [GeneID=920] CD8 thymocytes versus those after stimulation with anti-Valpha2 antibodies."} {"geneset":"GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of control CD4 [GeneID=920] CD8 thymocytes versus those after stimulation with anti-Valpha2 antibodies."} {"geneset":"GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of control CD4 [GeneID=920] CD8 thymocytes versus those after stimulation with anti-Vbeta5 antibodies."} {"geneset":"GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of control CD4 [GeneID=920] CD8 thymocytes versus those after stimulation with anti-Vbeta5 antibodies."} {"geneset":"GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes stimulated with anti-Valpha2 antibodies versus CD4 [GeneID=920] CD8 thymocytes stimulated with anti-beta5 antibodies."} {"geneset":"GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes stimulated with anti-Valpha2 antibodies versus CD4 [GeneID=920] CD8 thymocytes stimulated with anti-beta5 antibodies."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] CD8 thymocytes."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] CD8 thymocytes."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP","description":"Genes up-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] thymocytes."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN","description":"Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] thymocytes."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP","description":"Genes up-regulated in comparison of intrathymic T progenitor cells (ITTP) versus naive CD4 [GeneID=920] T cells from cord blood."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN","description":"Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus naive CD4 [GeneID=920] T cells from cord blood."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP","description":"Genes up-regulated in comparison of intrathymic T progenitor cells (ITTP) versus naive CD4 [GeneID=920] T cells from adult blood."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN","description":"Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus naive CD4 [GeneID=920] T cells from adult blood."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP","description":"Genes up-regulated in comparison of intrathymic T progenitor cells (ITTP) versus thymic stromal cells."} {"geneset":"GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN","description":"Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus thymic stromal cells."} {"geneset":"GSE1460_DP_VS_CD4_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_DP_VS_CD4_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus T cells from cord blood."} {"geneset":"GSE1460_DP_VS_CD4_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_DP_VS_CD4_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus T cells from cord blood."} {"geneset":"GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus naive CD4 [GeneID=920] T cells from cord blood."} {"geneset":"GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus naive CD4 [GeneID=920] T cells from cord blood."} {"geneset":"GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus naive CD4 [GeneID=920] T cells from adult blood."} {"geneset":"GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus naive CD4 [GeneID=920] T cells from adult blood."} {"geneset":"GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus thymic stromal cells."} {"geneset":"GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus thymic stromal cells."} {"geneset":"GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] thymocytes versus naive CD4 [GeneID=920] T cells from cord blood."} {"geneset":"GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] thymocytes versus naive CD4 [GeneID=920] T cells from cord blood."} {"geneset":"GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] thymocytes versus naive CD4 [GeneID=920] T cells from adult blood."} {"geneset":"GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] thymocytes versus naive CD4 [GeneID=920] T cells from adult blood."} {"geneset":"GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] thymocytes versus thymic stromal cells."} {"geneset":"GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] thymocytes versus thymic stromal cells."} {"geneset":"GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from cord blood versus those from adult blood."} {"geneset":"GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from cord blood versus those from adult blood."} {"geneset":"GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP","description":"Genes up-regulated in naive CD4 [GeneID=920] T cells from cord blood versus thymic stromal cells."} {"geneset":"GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN","description":"Genes down-regulated in naive CD4 [GeneID=920] T cells from cord blood versus thymic stromal cells."} {"geneset":"GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_UP","description":"Genes up-regulated in naive CD4 [GeneID=920] T cells from adult blood versus thymic stromal cells."} {"geneset":"GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN","description":"Genes down-regulated in naive CD4 [GeneID=920] T cells from adult blood versus thymic stromal cells."} {"geneset":"GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 20 min."} {"geneset":"GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 20 min."} {"geneset":"GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 40 min."} {"geneset":"GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 40 min."} {"geneset":"GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 60 min."} {"geneset":"GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 60 min."} {"geneset":"GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 80 min."} {"geneset":"GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 80 min."} {"geneset":"GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 120 min."} {"geneset":"GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 120 min."} {"geneset":"GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 240 min."} {"geneset":"GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 240 min."} {"geneset":"GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min."} {"geneset":"GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min."} {"geneset":"GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of macrophage cells stimulated with LPS (TLR4 agonist) for 20 min versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min."} {"geneset":"GSE14769_20MIN_VS_360MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_20MIN_VS_360MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of macrophage cells stimulated with LPS (TLR4 agonist) for 20 min versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min."} {"geneset":"GSE14769_40MIN_VS_360MIN_LPS_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_40MIN_VS_360MIN_LPS_BMDM_UP","description":"Genes up-regulated in comparison of macrophage cells stimulated with LPS (TLR4 agonist) for 40 min versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min."} {"geneset":"GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN","description":"Genes down-regulated in comparison of macrophage cells stimulated with LPS (TLR4 agonist) for 40 min versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min."} {"geneset":"GSE15215_CD2_POS_VS_NEG_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15215_CD2_POS_VS_NEG_PDC_UP","description":"Genes up-regulated in comparison of CD2+ plasmacytoid dendritic cells (DC) versus CD2- cells."} {"geneset":"GSE15215_CD2_POS_VS_NEG_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15215_CD2_POS_VS_NEG_PDC_DN","description":"Genes down-regulated in comparison of CD2+ plasmacytoid dendritic cells (DC) versus CD2- cells."} {"geneset":"GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus activated CD8 T cells."} {"geneset":"GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus activated CD8 T cells."} {"geneset":"GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells from ELF4 [GeneID=2000] defficient mice versus activated CD8 T cells from ELF4 [GeneID=2000] defficient animals."} {"geneset":"GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells from ELF4 [GeneID=2000] defficient mice versus activated CD8 T cells from ELF4 [GeneID=2000] defficient animals."} {"geneset":"GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells from ELF4 [GeneID=2000] defficient mice versus those from wild type animals."} {"geneset":"GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells from ELF4 [GeneID=2000] defficient mice versus those from wild type animals."} {"geneset":"GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP","description":"Genes up-regulated in comparison of activated CD8 T cells from ELF4 [GeneID=2000] defficient mice versus those from wild type animals."} {"geneset":"GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN","description":"Genes down-regulated in comparison of activated CD8 T cells from ELF4 [GeneID=2000] defficient mice versus those from wild type animals."} {"geneset":"GSE15659_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_TREG_VS_TCONV_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) versus conventional T cells."} {"geneset":"GSE15659_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_TREG_VS_TCONV_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) versus conventional T cells."} {"geneset":"GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus PTPRC+ [GeneID=5788] CD4 [GeneID=920] T cells."} {"geneset":"GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus PTPRC+ [GeneID=5788] CD4 [GeneID=920] T cells."} {"geneset":"GSE15659_NAIVE_CD4_TCELL_VS_RESTING_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NAIVE_CD4_TCELL_VS_RESTING_TREG_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus resting regulatory T cell (Treg)."} {"geneset":"GSE15659_NAIVE_CD4_TCELL_VS_RESTING_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NAIVE_CD4_TCELL_VS_RESTING_TREG_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus resting regulatory T cell (Treg)."} {"geneset":"GSE15659_NAIVE_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NAIVE_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus non-suppressive T cells."} {"geneset":"GSE15659_NAIVE_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NAIVE_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus non-suppressive T cells."} {"geneset":"GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus activated regulatory T cell (Treg)."} {"geneset":"GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus activated regulatory T cell (Treg)."} {"geneset":"GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_UP","description":"Genes up-regulated in comparison of PTPRC- [GeneID=5788] CD4 [GeneID=920] T cells versus PTPRC+ [GeneID=5788] resting regulatory T cell (Treg)."} {"geneset":"GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_DN","description":"Genes down-regulated in comparison of PTPRC- [GeneID=5788] CD4 [GeneID=920] T cells versus PTPRC+ [GeneID=5788] resting regulatory T cell (Treg)."} {"geneset":"GSE15659_CD45RA_NEG_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_CD45RA_NEG_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_UP","description":"Genes up-regulated in comparison of PTPRC- [GeneID=5788] CD4 [GeneID=920] T cells versus non-suppressive T cells."} {"geneset":"GSE15659_CD45RA_NEG_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_CD45RA_NEG_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN","description":"Genes down-regulated in comparison of PTPRC- [GeneID=5788] CD4 [GeneID=920] T cells versus non-suppressive T cells."} {"geneset":"GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_UP","description":"Genes up-regulated in comparison of PTPRC- [GeneID=5788] CD4 [GeneID=920] T cells versus activated regulatory T cell (Treg)."} {"geneset":"GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_DN","description":"Genes down-regulated in comparison of PTPRC- [GeneID=5788] CD4 [GeneID=920] T cells versus activated regulatory T cell (Treg)."} {"geneset":"GSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_UP","description":"Genes up-regulated in comparison of resting regulatory T cell (Treg) versus non-suppressive T cells."} {"geneset":"GSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_DN","description":"Genes down-regulated in comparison of resting regulatory T cell (Treg) versus non-suppressive T cells."} {"geneset":"GSE15659_RESTING_VS_ACTIVATED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_RESTING_VS_ACTIVATED_TREG_UP","description":"Genes up-regulated in comparison of resting regulatory T cell (Treg) versus activated regulatory T cell (Treg)."} {"geneset":"GSE15659_RESTING_VS_ACTIVATED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_RESTING_VS_ACTIVATED_TREG_DN","description":"Genes down-regulated in comparison of resting regulatory T cell (Treg) versus activated regulatory T cell (Treg)."} {"geneset":"GSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_UP","description":"Genes up-regulated in comparison of non-suppressive T cells versus activated regulatory T cell (Treg)."} {"geneset":"GSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_DN","description":"Genes down-regulated in comparison of non-suppressive T cells versus activated regulatory T cell (Treg)."} {"geneset":"GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells from bone marrow versus those from spleen."} {"geneset":"GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells from bone marrow versus those from spleen."} {"geneset":"GSE15750_WT_VS_TRAF6KO_DAY6_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15750_WT_VS_TRAF6KO_DAY6_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of wild type CD8 effector T cells at day 6 versus those from mice defficient for TRAF6 [GeneID=7189] at day 6."} {"geneset":"GSE15750_WT_VS_TRAF6KO_DAY6_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15750_WT_VS_TRAF6KO_DAY6_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of wild type CD8 effector T cells at day 6 versus those from mice defficient for TRAF6 [GeneID=7189] at day 6."} {"geneset":"GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of wild type CD8 effector T cells at day 10 versus those from mice defficient for TRAF6 [GeneID=7189] at day 10."} {"geneset":"GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of wild type CD8 effector T cells at day 10 versus those from mice defficient for TRAF6 [GeneID=7189] at day 10."} {"geneset":"GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of wild type CD8 effector T cells at day 6 versus those at day 10."} {"geneset":"GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of wild type CD8 effector T cells at day 6 versus those at day 10."} {"geneset":"GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of wild type CD8 effector T cells at day 6 versus those from mice defficient for TRAF6 [GeneID=7189] at day 10."} {"geneset":"GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of wild type CD8 effector T cells at day 6 versus those from mice defficient for TRAF6 [GeneID=7189] at day 10."} {"geneset":"GSE15767_MED_VS_SCS_MAC_LN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15767_MED_VS_SCS_MAC_LN_UP","description":"Genes up-regulated in comparison of medullary macrophages versus subcapsular sinus (SCS) macrophages."} {"geneset":"GSE15767_MED_VS_SCS_MAC_LN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15767_MED_VS_SCS_MAC_LN_DN","description":"Genes down-regulated in comparison of medullary macrophages versus subcapsular sinus (SCS) macrophages."} {"geneset":"GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 24 h."} {"geneset":"GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 24 h."} {"geneset":"GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with IL12 ."} {"geneset":"GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with IL12 ."} {"geneset":"GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 48 h."} {"geneset":"GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 48 h."} {"geneset":"GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 48 h after stimulation with IL12."} {"geneset":"GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 48 h after stimulation with IL12."} {"geneset":"GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 48 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 48 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 72 h."} {"geneset":"GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 72 h."} {"geneset":"GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after stimulation with IL12."} {"geneset":"GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after stimulation with IL12."} {"geneset":"GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after treatment with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after treatment with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IL12_24H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IL12_24H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after stimulation with IL12."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IL12_24H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IL12_24H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after stimulation with IL12."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IFNAB_24H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IFNAB_24H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IFNAB_24H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IFNAB_24H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after treatment with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after treatment with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after stimulation with IL12."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after stimulation with IL12."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after treatment with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after treatment with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IL12_72H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IL12_72H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after stimulation with IL12."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IL12_72H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IL12_72H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after stimulation with IL12."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after stimulation with antigen-B7-1."} {"geneset":"GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_UP","description":"Genes up-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after treatment with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_DN","description":"Genes down-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after treatment with trichostatin A (TSA) [PubChem=5562]."} {"geneset":"GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_UP","description":"Genes up-regulated in comparison of rested memory CD8 T cells from pmel-1 mice versus rested naive CD8 T cells from pmel-1 mice."} {"geneset":"GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in comparison of rested memory CD8 T cells from pmel-1 mice versus rested naive CD8 T cells from pmel-1 mice."} {"geneset":"GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP","description":"Genes up-regulated in comparison of stimulated memory CD8 T cells from pmel-1 mice versus stimulated naive CD8 T cells from pmel-1 mice."} {"geneset":"GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_DN","description":"Genes down-regulated in comparison of stimulated memory CD8 T cells from pmel-1 mice versus stimulated naive CD8 T cells from pmel-1 mice."} {"geneset":"GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of stimulated memory CD8 T cells from pmel-1 mice versus unstimulated memory CD8 T cells from pmel-1 mice."} {"geneset":"GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of stimulated memory CD8 T cells from pmel-1 mice versus unstimulated memory CD8 T cells from pmel-1 mice."} {"geneset":"GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_UP","description":"Genes up-regulated in comparison of stimulated naive CD8 T cells from pmel-1 mice versus unstimulated naive CD8 T cells from pmel-1 mice."} {"geneset":"GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in comparison of stimulated naive CD8 T cells from pmel-1 mice versus unstimulated naive CD8 T cells from pmel-1 mice."} {"geneset":"GSE16755_CTRL_VS_IFNA_TREATED_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16755_CTRL_VS_IFNA_TREATED_MAC_UP","description":"Genes up-regulated in comparison of control macrophages versus macrophages treated with interferon alpha."} {"geneset":"GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN","description":"Genes down-regulated in comparison of control macrophages versus macrophages treated with interferon alpha."} {"geneset":"GSE17580_TREG_VS_TEFF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17580_TREG_VS_TEFF_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) from uninfected mice versus T effector cells from uninfected mice."} {"geneset":"GSE17580_TREG_VS_TEFF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17580_TREG_VS_TEFF_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) from uninfected mice versus T effector cells from uninfected mice."} {"geneset":"GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) from mice infected with S. mansoni versus T effector cells from the infected mice."} {"geneset":"GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) from mice infected with S. mansoni versus T effector cells from the infected mice."} {"geneset":"GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP","description":"Genes up-regulated in comparison of T effector cells from uninfected mice versus T effector cells from mice infected with S. mansoni."} {"geneset":"GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_DN","description":"Genes down-regulated in comparison of T effector cells from uninfected mice versus T effector cells from mice infected with S. mansoni."} {"geneset":"GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) from uninfected mice versus regulatory T cell (Treg) from mice infected with S. mansoni."} {"geneset":"GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) from uninfected mice versus regulatory T cell (Treg) from mice infected with S. mansoni."} {"geneset":"GSE17721_CTRL_VS_LPS_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with LPS (TLR4 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_LPS_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with LPS (TLR4 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_LPS_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_1H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_LPS_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_1H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_LPS_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_2H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with LPS (TLR4 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_LPS_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_2H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with LPS (TLR4 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_LPS_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_4H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_LPS_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_4H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_LPS_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_6H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with LPS (TLR4 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_LPS_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_6H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with LPS (TLR4 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_LPS_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_8H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with LPS (TLR4 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_LPS_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_8H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with LPS (TLR4 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_LPS_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_12H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with LPS (TLR4 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_LPS_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_12H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with LPS (TLR4 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_LPS_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_24H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with LPS (TLR4 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_LPS_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_LPS_24H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with LPS (TLR4 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with poly(I:C) (TLR3 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with poly(I:C) (TLR3 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_1H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with poly(I:C) (TLR3 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_1H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with poly(I:C) (TLR3 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_2H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with poly(I:C) (TLR3 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_2H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with poly(I:C) (TLR3 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_4H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with poly(I:C) (TLR3 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_4H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with poly(I:C) (TLR3 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_6H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with poly(I:C) (TLR3 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_6H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with poly(I:C) (TLR3 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_8H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with poly(I:C) (TLR3 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_8H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with poly(I:C) (TLR3 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_12H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with poly(I:C) (TLR3 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_12H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with poly(I:C) (TLR3 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_24H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with poly(I:C) (TLR3 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_POLYIC_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_POLYIC_24H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with poly(I:C) (TLR3 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_CPG_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with CpG DNA (TLR9 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_CPG_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with CpG DNA (TLR9 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_CPG_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_1H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with CpG DNA (TLR9 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_CPG_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_1H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with CpG DNA (TLR9 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_CPG_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_2H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with CpG DNA (TLR9 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_CPG_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_2H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with CpG DNA (TLR9 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_CPG_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_4H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_CPG_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_4H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_CPG_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_6H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with CpG DNA (TLR9 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_CPG_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_6H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with CpG DNA (TLR9 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_CPG_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_8H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_CPG_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_8H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_CPG_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_12H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_CPG_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_12H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_CPG_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_24H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_CPG_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_CPG_24H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 8 h versus those stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_UP","description":"Genes up-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_DN","description":"Genes down-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 0.5 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 0.5 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 1 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 1 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 1 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 1 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 2 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 2 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 4 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 4 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 6 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 6 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 8 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 8 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 12 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 12 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 16 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 16 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 24 h."} {"geneset":"GSE17721_LPS_VS_POLYIC_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_POLYIC_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 24 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 1 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 1 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 2 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 2 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 6 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 6 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 16 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 16 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 24 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h."} {"geneset":"GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 24 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 1 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 1 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 2 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 2 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 6 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 6 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 16 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 16 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 4 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 4 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 1 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 1 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h."} {"geneset":"GSE17721_LPS_VS_PAM3CSK4_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_PAM3CSK4_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 1 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 1 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 1 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 1 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 2 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 2 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 2 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 2 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 6 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 6 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 6 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 6 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 16 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 16 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 16 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 16 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 24 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_POLYIC_VS_CPG_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_CPG_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 24 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_LPS_VS_CPG_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h."} {"geneset":"GSE17721_LPS_VS_CPG_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h."} {"geneset":"GSE17721_LPS_VS_CPG_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 1 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 1 h."} {"geneset":"GSE17721_LPS_VS_CPG_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 1 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 1 h."} {"geneset":"GSE17721_LPS_VS_CPG_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 2 h."} {"geneset":"GSE17721_LPS_VS_CPG_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 2 h."} {"geneset":"GSE17721_LPS_VS_CPG_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_LPS_VS_CPG_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_LPS_VS_CPG_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 6 h."} {"geneset":"GSE17721_LPS_VS_CPG_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 6 h."} {"geneset":"GSE17721_LPS_VS_CPG_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_LPS_VS_CPG_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_LPS_VS_CPG_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_LPS_VS_CPG_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_LPS_VS_CPG_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 16 h."} {"geneset":"GSE17721_LPS_VS_CPG_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 16 h."} {"geneset":"GSE17721_LPS_VS_CPG_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_LPS_VS_CPG_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_CPG_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_0.5H_VS_12H_LPS_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_LPS_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 12 h."} {"geneset":"GSE17721_0.5H_VS_12H_LPS_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_LPS_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 12 h."} {"geneset":"GSE17721_0.5H_VS_4H_LPS_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_LPS_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 4 h."} {"geneset":"GSE17721_0.5H_VS_4H_LPS_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_LPS_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 4 h."} {"geneset":"GSE17721_0.5H_VS_8H_LPS_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_LPS_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 8 h."} {"geneset":"GSE17721_0.5H_VS_8H_LPS_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_LPS_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 8 h."} {"geneset":"GSE17721_0.5H_VS_24H_LPS_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_LPS_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 24 h."} {"geneset":"GSE17721_0.5H_VS_24H_LPS_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_LPS_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 24 h."} {"geneset":"GSE17721_12H_VS_24H_LPS_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_LPS_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus those stimulated at 24 h."} {"geneset":"GSE17721_12H_VS_24H_LPS_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_LPS_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus those stimulated at 24 h."} {"geneset":"GSE17721_0.5H_VS_12H_POLYIC_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_POLYIC_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 4 h."} {"geneset":"GSE17721_0.5H_VS_12H_POLYIC_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_POLYIC_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 4 h."} {"geneset":"GSE17721_0.5H_VS_4H_POLYIC_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_POLYIC_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 8 h."} {"geneset":"GSE17721_0.5H_VS_4H_POLYIC_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_POLYIC_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 8 h."} {"geneset":"GSE17721_0.5H_VS_8H_POLYIC_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_POLYIC_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 8 h."} {"geneset":"GSE17721_0.5H_VS_8H_POLYIC_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_POLYIC_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 8 h."} {"geneset":"GSE17721_0.5H_VS_24H_POLYIC_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_POLYIC_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 24 h."} {"geneset":"GSE17721_0.5H_VS_24H_POLYIC_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_POLYIC_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 24 h."} {"geneset":"GSE17721_4H_VS_24H_POLYIC_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_4H_VS_24H_POLYIC_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus those stimulated at 24 h."} {"geneset":"GSE17721_4H_VS_24H_POLYIC_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_4H_VS_24H_POLYIC_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus those stimulated at 24 h."} {"geneset":"GSE17721_12H_VS_24H_POLYIC_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_POLYIC_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus those stimulated at 24 h."} {"geneset":"GSE17721_12H_VS_24H_POLYIC_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_POLYIC_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus those stimulated at 24 h."} {"geneset":"GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 12 h."} {"geneset":"GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 12 h."} {"geneset":"GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 4 h."} {"geneset":"GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 4 h."} {"geneset":"GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 8 h."} {"geneset":"GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 8 h."} {"geneset":"GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 24 h."} {"geneset":"GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 24 h."} {"geneset":"GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at all time points versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h only."} {"geneset":"GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at all time points versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h only."} {"geneset":"GSE17721_12H_VS_24H_PAM3CSK4_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_PAM3CSK4_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h."} {"geneset":"GSE17721_12H_VS_24H_PAM3CSK4_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_PAM3CSK4_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h."} {"geneset":"GSE17721_0.5H_VS_12H_CPG_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_CPG_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_0.5H_VS_12H_CPG_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_CPG_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 12 h."} {"geneset":"GSE17721_0.5H_VS_4H_CPG_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_CPG_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_0.5H_VS_4H_CPG_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_CPG_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 4 h."} {"geneset":"GSE17721_0.5H_VS_8H_CPG_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_CPG_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_0.5H_VS_8H_CPG_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_CPG_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 8 h."} {"geneset":"GSE17721_0.5H_VS_24H_CPG_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_CPG_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_0.5H_VS_24H_CPG_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_CPG_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_4_VS_24H_CPG_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_4_VS_24H_CPG_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 4 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_4_VS_24H_CPG_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_4_VS_24H_CPG_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 4 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_12H_VS_24H_CPG_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_CPG_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 12 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_12H_VS_24H_CPG_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_CPG_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 12 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h."} {"geneset":"GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 12 h."} {"geneset":"GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 4 h."} {"geneset":"GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 8 h."} {"geneset":"GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 4 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 4 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 12 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 12 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h."} {"geneset":"GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 0.5 h."} {"geneset":"GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 0.5 h."} {"geneset":"GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 1 h."} {"geneset":"GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 1 h."} {"geneset":"GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 2 h."} {"geneset":"GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 2 h."} {"geneset":"GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 4 h."} {"geneset":"GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 4 h."} {"geneset":"GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 6 h."} {"geneset":"GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 6 h."} {"geneset":"GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 12 h."} {"geneset":"GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 12 h."} {"geneset":"GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 24 h."} {"geneset":"GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 24 h."} {"geneset":"GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 48 h."} {"geneset":"GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 48 h."} {"geneset":"GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 0.5 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 0.5 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 1 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 1 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 2 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 2 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 4 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 4 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 6 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 6 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 24 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 24 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 48 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 48 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 72 h."} {"geneset":"GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 72 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 0.5 h versus the untreated cells at 0.5 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 0.5 h versus the untreated cells at 0.5 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_1H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_1H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 1 h versus the untreated cells at 1 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_1H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_1H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 1 h versus the untreated cells at 1 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 2 h versus the untreated cells at 2 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 2 h versus the untreated cells at 2 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 4 h versus the untreated cells at 4 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 4 h versus the untreated cells at 4 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 6 h versus the untreated cells at 6 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 6 h versus the untreated cells at 6 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h versus the untreated cells at 12 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h versus the untreated cells at 12 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 24 h versus the untreated cells at 24 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 24 h versus the untreated cells at 24 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 48 h versus the untreated cells at 48 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 48 h versus the untreated cells at 48 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 72 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 72 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0.5 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0.5 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 1 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 1 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 2 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 2 h versus the untreated cells at 72 h."} {"geneset":"GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 0.5 h versus those at 72 h."} {"geneset":"GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 0.5 h versus those at 72 h."} {"geneset":"GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 1.5 h versus those at 72 h."} {"geneset":"GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 1.5 h versus those at 72 h."} {"geneset":"GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 2 h versus those at 72 h."} {"geneset":"GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 2 h versus those at 72 h."} {"geneset":"GSE18148_CBFB_KO_VS_WT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18148_CBFB_KO_VS_WT_TREG_UP","description":"Genes up-regualted in comparison of regulatory T cell (Treg) from CBFB [GeneID=865] deficient mice versus those from wild type animals."} {"geneset":"GSE18148_CBFB_KO_VS_WT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18148_CBFB_KO_VS_WT_TREG_DN","description":"Genes down-regualted in comparison of regulatory T cell (Treg) from CBFB [GeneID=865] deficient mice versus those from wild type animals."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 1 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 1 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 4 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 4 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 6 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 6 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 8 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 8 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 10 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 10 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 12 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 12 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 14 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 14 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 16 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 16 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 18 h."} {"geneset":"GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 18 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_1H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_1H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 1 h versus cDCs infected with Newcastle disease virus (NDV) at 1 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_1H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_1H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 1 h versus cDCs infected with Newcastle disease virus (NDV) at 1 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_2H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 2 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_2H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 2 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 6 h versus cDCs infected with Newcastle disease virus (NDV) at 6 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 6 h versus cDCs infected with Newcastle disease virus (NDV) at 6 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 10 h versus cDCs infected with Newcastle disease virus (NDV) at 10 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 10 h versus cDCs infected with Newcastle disease virus (NDV) at 10 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_UP","description":"Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 18 h versus cDCs infected with Newcastle disease virus (NDV) at 18 h."} {"geneset":"GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN","description":"Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 18 h versus cDCs infected with Newcastle disease virus (NDV) at 18 h."} {"geneset":"GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] low T cells at."} {"geneset":"GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] low T cells at."} {"geneset":"GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] high T cells at."} {"geneset":"GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] high T cells at."} {"geneset":"GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of effector CD8 IL2RA [GeneID=3559] low T cells versus effector CD8 IL2RA [GeneID=3559] high cells."} {"geneset":"GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of effector CD8 IL2RA [GeneID=3559] low T cells versus effector CD8 IL2RA [GeneID=3559] high cells."} {"geneset":"GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive vs effector CD8 T cells (3.5 days postinfection)."} {"geneset":"GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive vs effector CD8 T cells (3.5 days postinfection)."} {"geneset":"GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of contols neutrophils versus those infected with a bacterium (F. nucleatum)."} {"geneset":"GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of contols neutrophils versus those infected with a bacterium (F. nucleatum)."} {"geneset":"GSE20366_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_TREG_VS_TCONV_UP","description":"Genes up-regulated in comparison of TregCD103-Klrg1 versus TconvLP (see Table 1S in the paper for details)."} {"geneset":"GSE20366_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_TREG_VS_TCONV_DN","description":"Genes down-regulated in comparison of TregCD103-Klrg1 versus TconvLP (see Table 1S in the paper for details)."} {"geneset":"GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP","description":"Genes up-regulated in comparison of TregLP versus Homeo Convert (see Table 1S in the paper for details)."} {"geneset":"GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_DN","description":"Genes down-regulated in comparison of TregLP versus Homeo Convert (see Table 1S in the paper for details)."} {"geneset":"GSE20366_EX_VIVO_VS_DEC205_CONVERSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_EX_VIVO_VS_DEC205_CONVERSION_UP","description":"Genes up-regulated in comparison of TregLP versus DEC-Pept Convert (see Table 1S in the paper for details)."} {"geneset":"GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN","description":"Genes down-regulated in comparison of TregLP versus DEC-Pept Convert (see Table 1S in the paper for details)."} {"geneset":"GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in comparison of TconvLP versus Homeo Foxp3- (see Table 1S in the paper for details)."} {"geneset":"GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in comparison of TconvLP versus Homeo Foxp3- (see Table 1S in the paper for details)."} {"geneset":"GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in comparison of TconvLP versus DEC-Pept CD25- (see Table S1 in the paper for details)."} {"geneset":"GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in comparison of TconvLP versus DEC-Pept CD25- (see Table S1 in the paper for details)."} {"geneset":"GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP","description":"Genes up-regulated in comparison of Homeo Convert versus Homeo Foxp3- (see Table 1S in the paper for details)."} {"geneset":"GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN","description":"Genes down-regulated in comparison of Homeo Convert versus Homeo Foxp3- (see Table 1S in the paper for details)."} {"geneset":"GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP","description":"Genes up-regulated in comparison of DEC-Pept Convert versus DEC-Pept CD25- (see Table 1S in the paper for details)."} {"geneset":"GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_DN","description":"Genes down-regulated in comparison of DEC-Pept Convert versus DEC-Pept CD25- (see Table 1S in the paper for details)."} {"geneset":"GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_UP","description":"Genes up-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1- (see Table 1S in the paper for details)."} {"geneset":"GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN","description":"Genes down-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1- (see Table 1S in the paper for details)."} {"geneset":"GSE20366_CD103_KLRG1_DP_VS_DN_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_CD103_KLRG1_DP_VS_DN_TREG_UP","description":"Genes up-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1+ (see Table 1S in the paper for details)."} {"geneset":"GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN","description":"Genes down-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1+ (see Table 1S in the paper for details)."} {"geneset":"GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP","description":"Genes up-regulated in comparison of TregCD103+Klrg1- versus TregCD103+Klrg1+ (see Table 1S in the paper for details)."} {"geneset":"GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN","description":"Genes down-regulated in comparison of TregCD103+Klrg1- versus TregCD103+Klrg1+ (see Table 1S in the paper for details)."} {"geneset":"GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in comparison of TregLP versus TconvLP (see Table 1S in the paper for details)."} {"geneset":"GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in comparison of TregLP versus TconvLP (see Table 1S in the paper for details)."} {"geneset":"GSE20715_WT_VS_TLR4_KO_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_WT_VS_TLR4_KO_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice versus that from TLR4 [GeneID=7099] deficient animals."} {"geneset":"GSE20715_WT_VS_TLR4_KO_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_WT_VS_TLR4_KO_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice versus that from TLR4 [GeneID=7099] deficient animals."} {"geneset":"GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_UP","description":"Genes up-regulated in comparson of lung tissue from wild type mice subjected to ozone for 6 h vs that from TLR4 [GeneID=7099] deficient animal subjected to ozone for 6 h."} {"geneset":"GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_DN","description":"Genes down-regulated in comparson of lung tissue from wild type mice subjected to ozone for 6 h vs that from TLR4 [GeneID=7099] deficient animal subjected to ozone for 6 h."} {"geneset":"GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 24 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 24 h."} {"geneset":"GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 24 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 24 h."} {"geneset":"GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 48 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 48 h."} {"geneset":"GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 48 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 48 h."} {"geneset":"GSE20715_0H_VS_6H_OZONE_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_6H_OZONE_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from wild type mice subjected to ozone for 6 h."} {"geneset":"GSE20715_0H_VS_6H_OZONE_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_6H_OZONE_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from wild type mice subjected to ozone for 6 h."} {"geneset":"GSE20715_0H_VS_24H_OZONE_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_24H_OZONE_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from wild type mice subjected to ozone for 24 h."} {"geneset":"GSE20715_0H_VS_24H_OZONE_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_24H_OZONE_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from wild type mice subjected to ozone for 24 h."} {"geneset":"GSE20715_0H_VS_48H_OZONE_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_48H_OZONE_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from wild type mice subjected to ozone for 48 h."} {"geneset":"GSE20715_0H_VS_48H_OZONE_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_48H_OZONE_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from wild type mice subjected to ozone for 48 h."} {"geneset":"GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 6 h."} {"geneset":"GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 6 h."} {"geneset":"GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 24 h."} {"geneset":"GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 24 h."} {"geneset":"GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP","description":"Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 48 h."} {"geneset":"GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN","description":"Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 48 h."} {"geneset":"GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) treated with immunosuppressive DNA versus the untreated cells."} {"geneset":"GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATEDIN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATEDIN_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) treated with immunosuppressive DNA versus the untreated cells."} {"geneset":"GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) treated with CpG DNA (TLR9 agonist) DNA versus the untreated cells."} {"geneset":"GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) treated with CpG DNA (TLR9 agonist) DNA versus the untreated cells."} {"geneset":"GSE22045_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22045_TREG_VS_TCONV_UP","description":"Genes up-regulated in comparison of regulatory T cell (Treg) versus conventional T cells."} {"geneset":"GSE22045_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22045_TREG_VS_TCONV_DN","description":"Genes down-regulated in comparison of regulatory T cell (Treg) versus conventional T cells."} {"geneset":"GSE22886_CD8_VS_CD4_NAIVE_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_CD8_VS_CD4_NAIVE_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus naive CD4 [GeneID=920] T cells."} {"geneset":"GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus naive CD4 [GeneID=920] T cells."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus naive CD4 [GeneID=920] CD8 T cells."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus naive CD4 [GeneID=920] CD8 T cells."} {"geneset":"GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP","description":"Genes up-regulated in comparison of unstimulated memory CD4 [GeneID=920] CD8 T cells versus stimulated CD4 [GeneID=920] CD8 T cells."} {"geneset":"GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_DN","description":"Genes down-regulated in comparison of unstimulated memory CD4 [GeneID=920] CD8 T cells versus stimulated CD4 [GeneID=920] CD8 T cells."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulated memory CD4 [GeneID=920] CD8 T cells."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulated memory CD4 [GeneID=920] CD8 T cells."} {"geneset":"GSE22886_NAIVE_TCELL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_TCELL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated NK cells."} {"geneset":"GSE22886_NAIVE_TCELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_TCELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated NK cells."} {"geneset":"GSE22886_NAIVE_VS_MEMORY_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_VS_MEMORY_TCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated memory CD4 [GeneID=920] CD8 T cells."} {"geneset":"GSE22886_NAIVE_VS_MEMORY_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_VS_MEMORY_TCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated memory CD4 [GeneID=920] CD8 T cells."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus unstimulated NK cells."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus unstimulated NK cells."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulated NK cells."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulated NK cells."} {"geneset":"GSE22886_TCELL_VS_BCELL_NAIVE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_TCELL_VS_BCELL_NAIVE_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus naive B cells."} {"geneset":"GSE22886_TCELL_VS_BCELL_NAIVE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_TCELL_VS_BCELL_NAIVE_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus naive B cells."} {"geneset":"GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus naive B cells."} {"geneset":"GSE22886_CD8_TCELL_VS_BCELL_NAIVE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_CD8_TCELL_VS_BCELL_NAIVE_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus naive B cells."} {"geneset":"GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus naive B cells."} {"geneset":"GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus naive B cells."} {"geneset":"GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of naive B cells versus memory IgG IgA B cells."} {"geneset":"GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of naive B cells versus memory IgG IgA B cells."} {"geneset":"GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of naive B cells versus memory IgM B cells."} {"geneset":"GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of naive B cells versus memory IgM B cells."} {"geneset":"GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP","description":"Genes up-regulated in comparison of memory IgG IgA B cells versus memory IgM B cells."} {"geneset":"GSE22886_IGA_VS_IGM_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGA_VS_IGM_MEMORY_BCELL_DN","description":"Genes down-regulated in comparison of memory IgG IgA B cells versus memory IgM B cells."} {"geneset":"GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of naive B cells versus blood plasma cells."} {"geneset":"GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of naive B cells versus blood plasma cells."} {"geneset":"GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of naive B cells versus plasma cells from bone marrow and blood."} {"geneset":"GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of naive B cells versus plasma cells from bone marrow and blood."} {"geneset":"GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of memory IgG IgA B cells versus blood plasma cells."} {"geneset":"GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of memory IgG IgA B cells versus blood plasma cells."} {"geneset":"GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of memory IgG IgA B cells versus plasma cells from bone marrow and blood."} {"geneset":"GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of memory IgG IgA B cells versus plasma cells from bone marrow and blood."} {"geneset":"GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of memory IgM B cells versus blood plasma cells."} {"geneset":"GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of memory IgM B cells versus blood plasma cells."} {"geneset":"GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP","description":"Genes up-regulated in comparison of memory IgM B cells versus plasma cells from bone marrow and blood."} {"geneset":"GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN","description":"Genes down-regulated in comparison of memory IgM B cells versus plasma cells from bone marrow and blood."} {"geneset":"GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP","description":"Genes up-regulated in comparison of monocytes cultured for 0 days versus those cultured for 1 day."} {"geneset":"GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN","description":"Genes down-regulated in comparison of monocytes cultured for 0 days versus those cultured for 1 day."} {"geneset":"GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP","description":"Genes up-regulated in comparison of monocytes cultured for 0 days versus those cultured for 7 days."} {"geneset":"GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN","description":"Genes down-regulated in comparison of monocytes cultured for 0 days versus those cultured for 7 days."} {"geneset":"GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP","description":"Genes up-regulated in comparison of monocytes cultured for 1 day versus those cultured for 7 days."} {"geneset":"GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN","description":"Genes down-regulated in comparison of monocytes cultured for 1 day versus those cultured for 7 days."} {"geneset":"GSE22886_NEUTROPHIL_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NEUTROPHIL_VS_DC_UP","description":"Genes up-regulated in comparison of neutrophils versus dendritic cells (DC)."} {"geneset":"GSE22886_NEUTROPHIL_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NEUTROPHIL_VS_DC_DN","description":"Genes down-regulated in comparison of neutrophils versus dendritic cells (DC)."} {"geneset":"GSE22886_NEUTROPHIL_VS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NEUTROPHIL_VS_MONOCYTE_UP","description":"Genes up-regulated in comparison of neuthrophils versus monocytes."} {"geneset":"GSE22886_NEUTROPHIL_VS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NEUTROPHIL_VS_MONOCYTE_DN","description":"Genes down-regulated in comparison of neutrophils versusl monocytes."} {"geneset":"GSE22886_DC_VS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_DC_VS_MONOCYTE_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) versus monocytes."} {"geneset":"GSE22886_DC_VS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_DC_VS_MONOCYTE_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) versus monocytes."} {"geneset":"GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated neutrophils."} {"geneset":"GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated neutrophils."} {"geneset":"GSE22886_NAIVE_TCELL_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_TCELL_VS_DC_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated dendritic cells (DC)."} {"geneset":"GSE22886_NAIVE_TCELL_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_TCELL_VS_DC_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated dendritic cells (DC)."} {"geneset":"GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus monocytes cultured for 0 days."} {"geneset":"GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus monocytes cultured for 0 days."} {"geneset":"GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of naive B cells versus unstimulated neutrophils."} {"geneset":"GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of naive B cells versus unstimulated neutrophils."} {"geneset":"GSE22886_NAIVE_BCELL_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_DC_UP","description":"Genes up-regulated in comparison of naive B cells versus unstimulated dendritic cells (DC)."} {"geneset":"GSE22886_NAIVE_BCELL_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_DC_DN","description":"Genes down-regulated in comparison of naive B cells versus unstimulated dendritic cells (DC)."} {"geneset":"GSE22886_NAIVE_BCELL_VS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_MONOCYTE_UP","description":"Genes up-regulated in comparison of naive B cells versus day 0 monocytes."} {"geneset":"GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN","description":"Genes down-regulated in comparison of naive B cells versus day 0 monocytes."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus unstimulated neutrophils."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus unstimulated neutrophils."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_DC_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus unstimulated dendritic cells (DC)."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_DC_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus unstimulated dendritic cells (DC)."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus day 0 monocytes."} {"geneset":"GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus day 0 monocytes."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulated neutrophils."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulated neutrophils."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_DC_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulatd dendritic cells (DC)."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_DC_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulatd dendritic cells (DC)."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus day 0 monocytes."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus day 0 monocytes."} {"geneset":"GSE22886_TH1_VS_TH2_12H_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_TH1_VS_TH2_12H_ACT_UP","description":"Genes up-regulated in comparison of stimulated CD4 [GeneID=920] Th1 cells at 12 h versus stimulated CD4 [GeneID=920] Th2 cells at 12 h."} {"geneset":"GSE22886_TH1_VS_TH2_12H_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_TH1_VS_TH2_12H_ACT_DN","description":"Genes down-regulated in comparison of stimulated CD4 [GeneID=920] Th1 cells at 12 h versus stimulated CD4 [GeneID=920] Th2 cells at 12 h."} {"geneset":"GSE22886_TH1_VS_TH2_48H_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_TH1_VS_TH2_48H_ACT_UP","description":"Genes up-regulated in comparison of stimulated CD4 [GeneID=920] Th1 cells at 48 h versus stimulated CD4 [GeneID=920] Th2 cells at 48 h."} {"geneset":"GSE22886_TH1_VS_TH2_48H_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_TH1_VS_TH2_48H_ACT_DN","description":"Genes down-regulated in comparison of stimulated CD4 [GeneID=920] Th1 cells at 48 h versus stimulated CD4 [GeneID=920] Th2 cells at 48 h."} {"geneset":"GSE22886_IL2_VS_IL15_STIM_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IL2_VS_IL15_STIM_NKCELL_UP","description":"Genes up-regulated in comparison of NK cells stimulated with IL2 [GeneID=3558] at 16 h versus NK cells stimulated with IL15 [GeneID=3600] at 16 h."} {"geneset":"GSE22886_IL2_VS_IL15_STIM_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_IL2_VS_IL15_STIM_NKCELL_DN","description":"Genes down-regulated in comparison of NK cells stimulated with IL2 [GeneID=3558] at 16 h versus NK cells stimulated with IL15 [GeneID=3600] at 16 h."} {"geneset":"GSE22886_CTRL_VS_LPS_24H_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_CTRL_VS_LPS_24H_DC_UP","description":"Genes up-regulated in comparison of unstimulated dendritic cells (DC) versus 1 day DC stimulated with LPS (TLR4 agonist)."} {"geneset":"GSE22886_CTRL_VS_LPS_24H_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_CTRL_VS_LPS_24H_DC_DN","description":"Genes down-regulated in comparison of unstimulated dendritic cells (DC) versus 1 day DC stimulated with LPS (TLR4 agonist)."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 12 h."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 12 h."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 48 h."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 48 h."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th2 cells at 12 h."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th2 cells at 12 h."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th2 cells at 48 h."} {"geneset":"GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th2 cells at 48 h."} {"geneset":"GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP","description":"Genes up-regulated in comparison of unstimulated NK cells versus those stimulated with IL2 [GeneID=3558] at 16 h."} {"geneset":"GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN","description":"Genes down-regulated in comparison of unstimulated NK cells versus those stimulated with IL2 [GeneID=3558] at 16 h."} {"geneset":"GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_UP","description":"Genes up-regulated in comparison of unstimulated NK cells versus those stimulated with IL15 [GeneID=3600] at 16 h."} {"geneset":"GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN","description":"Genes down-regulated in comparison of unstimulated NK cells versus those stimulated with IL2 [GeneID=3600] at 16 h."} {"geneset":"GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_UP","description":"Genes up-regulated in comparison of Jurkat T cells stimulated in the presence of PD-1 versus controls."} {"geneset":"GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN","description":"Genes down-regulated in comparison of Jurkat T cells stimulated in the presence of PD-1 versus controls."} {"geneset":"GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells with progressing HIV infection versus those with controlled HIV infection."} {"geneset":"GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells with progressing HIV infection versus those with controlled HIV infection."} {"geneset":"GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of granulocytic myeloid derived suppressor cells (MDSC) versus neutrophils."} {"geneset":"GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of granulocytic myeloid derived suppressor cells (MDSC) versus neutrophils."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP","description":"Genes up-regulated in comparison of thymic progenitors versus DN2 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_DN","description":"Genes down-regulated in comparison of thymic progenitors versus DN2 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP","description":"Genes up-regulated in comparison of thymic progenitors versus DN3 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN","description":"Genes down-regulated in comparison of thymic progenitors versus DN3 thymocytes."} {"geneset":"GSE24142_DN2_VS_DN3_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_DN2_VS_DN3_THYMOCYTE_UP","description":"Genes up-regulated in comparison of DN2 thymocytes versus DN3 thymocytes."} {"geneset":"GSE24142_DN2_VS_DN3_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_DN2_VS_DN3_THYMOCYTE_DN","description":"Genes down-regulated in comparison of DN2 thymocytes versus DN3 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP","description":"Genes up-regulated in comparison of adult thymic progenitors versus adult DN2 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_DN","description":"Genes down-regulated in comparison of adult thymic progenitors versus adult DN2 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP","description":"Genes up-regulated in comparison of adult thymic progenitors versus adult DN3 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_DN","description":"Genes down-regulated in comparison of adult thymic progenitors versus adult DN3 thymocytes."} {"geneset":"GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP","description":"Genes up-regulated in adult DN2 thymocytes versus adult DN3 thymocytes."} {"geneset":"GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN","description":"Genes down-regulated in adult DN2 thymocytes versus adult DN3 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP","description":"Genes up-regulated in comparison of thymic progenitors versus fetal DN2 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_DN","description":"Genes down-regulated in comparison of thymic progenitors versus fetal DN2 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP","description":"Genes up-regulated in comparison of thymic progenitors versus fetal DN3 thymocytes."} {"geneset":"GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN","description":"Genes down-regulated in comparison of thymic progenitors versus fetal DN3 thymocytes."} {"geneset":"GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP","description":"Genes up-regulated in comparison of fetal DN2 thymocytes versus fetal DN3 thymocytes."} {"geneset":"GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN","description":"Genes down-regulated in comparison of fetal DN2 thymocytes versus fetal DN3 thymocytes."} {"geneset":"GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP","description":"Genes up-regulated in comparison of adult thymic progenitors versus fetal thymic progenitors."} {"geneset":"GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_DN","description":"Genes down-regulated in comparison of adult thymic progenitors versus fetal thymic progenitors."} {"geneset":"GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP","description":"Genes up-regulated in comparison of adult DN2 thymocytes versus fetal DN2 thymocytes."} {"geneset":"GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_DN","description":"Genes down-regulated in comparison of adult DN2 thymocytes versus fetal DN2 thymocytes."} {"geneset":"GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP","description":"Genes up-regulated in comparison of adult DN3 thymocytes versus fetal DN3 thymocytes."} {"geneset":"GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN","description":"Genes down-regulated in comparison of adult DN3 thymocytes versus fetal DN3 thymocytes."} {"geneset":"GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP","description":"Genes up-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 3."} {"geneset":"GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_DN","description":"Genes down-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 3."} {"geneset":"GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP","description":"Genes up-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 5."} {"geneset":"GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN","description":"Genes down-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 5."} {"geneset":"GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP","description":"Genes up-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 7."} {"geneset":"GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN","description":"Genes down-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 7."} {"geneset":"GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP","description":"Genes up-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 10."} {"geneset":"GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN","description":"Genes down-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 10."} {"geneset":"GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP","description":"Genes up-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 3 versus CD25- T cells incubated with IL4 [GeneID=3565] at day 3."} {"geneset":"GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN","description":"Genes down-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 3 versus CD25- T cells incubated with IL4 [GeneID=3565] at day 3."} {"geneset":"GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_UP","description":"Genes up-regulated in comparison of CD25+ T cells treated with IL4 [GeneID=3565] versus CD25- T cells treated with IL4 [GeneID=3565] at day 5."} {"geneset":"GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN","description":"Genes down-regulated in comparison of CD25+ T cells treated with IL4 [GeneID=3565] versus CD25- T cells treated with IL4 [GeneID=3565] at day 5."} {"geneset":"GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP","description":"Genes up-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 7 versus CD25- T cells treated with IL4 [GeneID=3565] at day 7."} {"geneset":"GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN","description":"Genes down-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 7 versus CD25- T cells treated with IL4 [GeneID=3565] at day 7."} {"geneset":"GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP","description":"Genes up-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 10 versus CD25- T cells treated with IL4 [GeneID=3565] at 10 h."} {"geneset":"GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN","description":"Genes down-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 10 versus CD25- T cells treated with IL4 [GeneID=3565] at 10 h."} {"geneset":"GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP","description":"Genes up-regulated in comparison of CD25+ T effector cells treated with IL4 [GeneID=3565] at day 3 versus untreated CD25- T cells at day 3."} {"geneset":"GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN","description":"Genes down-regulated in comparison of CD25+ T effector cells treated with IL4 [GeneID=3565] at day 3 versus untreated CD25- T cells at day 3."} {"geneset":"GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_UP","description":"Genes up-regulated in comparison of untreated CD25+ T effector cells at day 5 versus untreated CD25- T cells at day 5."} {"geneset":"GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN","description":"Genes down-regulated in comparison of untreated CD25+ T effector cells at day 5 versus untreated CD25- T cells at day 5."} {"geneset":"GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP","description":"Genes up-regulated in comparison of untreated CD25+ T effector cells at day 7 versus untreated CD25- T cells at day 7."} {"geneset":"GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN","description":"Genes down-regulated in comparison of untreated CD25+ T effector cells at day 7 versus untreated CD25- T cells at day 7."} {"geneset":"GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP","description":"Genes up-regulated in comparison of untreated CD25+ T effector cells at day 10 versus untreated CD25- T cells at day 10."} {"geneset":"GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN","description":"Genes down-regulated in comparison of untreated CD25+ T effector cells at day 10 versus untreated CD25- T cells at day 10."} {"geneset":"GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP","description":"Genes up-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 3 versus untreated CD25- T cells at day 3."} {"geneset":"GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN","description":"Genes down-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 3 versus untreated CD25- T cells at day 3."} {"geneset":"GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP","description":"Genes up-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 5 versus untreated CD25- T cells at day 5."} {"geneset":"GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN","description":"Genes down-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 5 versus untreated CD25- T cells at day 5."} {"geneset":"GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP","description":"Genes up-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 7 versus untreated CD25- T cells at day 7."} {"geneset":"GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN","description":"Genes down-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 7 versus untreated CD25- T cells at day 7."} {"geneset":"GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP","description":"Genes up-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 10 versus untreated CD25- T cells at day 10."} {"geneset":"GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN","description":"Genes down-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 10 versus untreated CD25- T cells at day 10."} {"geneset":"GSE25087_FETAL_VS_ADULT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25087_FETAL_VS_ADULT_TREG_UP","description":"Genes up-regulated in comparison of fetal regulatory T cell (Treg) versus adult regulatory T cell (Treg)."} {"geneset":"GSE25087_FETAL_VS_ADULT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25087_FETAL_VS_ADULT_TREG_DN","description":"Genes down-regulated in comparison of fetal regulatory T cell (Treg) versus adult regulatory T cell (Treg)."} {"geneset":"GSE25087_FETAL_VS_ADULT_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25087_FETAL_VS_ADULT_TCONV_UP","description":"Genes up-regulated in comparison of fetal conventional T cells versus adult conventional T cells."} {"geneset":"GSE25087_FETAL_VS_ADULT_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25087_FETAL_VS_ADULT_TCONV_DN","description":"Genes down-regulated in comparison of fetal conventional T cells versus adult conventional T cells."} {"geneset":"GSE25087_TREG_VS_TCONV_FETUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25087_TREG_VS_TCONV_FETUS_UP","description":"Genes up-regulated in comparison of fetal regulatory T cell (Treg) versus fetal conventional T cells."} {"geneset":"GSE25087_TREG_VS_TCONV_FETUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25087_TREG_VS_TCONV_FETUS_DN","description":"Genes down-regulated in comparison of fetal regulatory T cell (Treg) versus fetal conventional T cells."} {"geneset":"GSE25087_TREG_VS_TCONV_ADULT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25087_TREG_VS_TCONV_ADULT_UP","description":"Genes up-regulated in comparison of adult regulatory T cell (Treg) versus adult conventional T cells."} {"geneset":"GSE25087_TREG_VS_TCONV_ADULT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25087_TREG_VS_TCONV_ADULT_DN","description":"Genes down-regulated in comparison of adult regulatory T cell (Treg) versus adult conventional T cells."} {"geneset":"GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus PD-1 high CD8 T cells."} {"geneset":"GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus PD-1 high CD8 T cells."} {"geneset":"GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus PD-1 low CD8 T cells."} {"geneset":"GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus PD-1 low CD8 T cells."} {"geneset":"GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_UP","description":"Genes up-regulated in comparison of PD-1 high CD8 T cells versus PD-1 low CD8 T cells."} {"geneset":"GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN","description":"Genes down-regulated in comparison of PD-1 high CD8 T cells versus PD-1 low CD8 T cells."} {"geneset":"GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus CD4 [GeneID=920] T cells treated with leukocyte costimulatory blockade antibodies."} {"geneset":"GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus CD4 [GeneID=920] T cells treated with leukocyte costimulatory blockade antibodies."} {"geneset":"GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD8 T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies."} {"geneset":"GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD8 T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies."} {"geneset":"GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus the untreated CD8 T cells."} {"geneset":"GSE26669_CD4_VS_CD8_TCELL_IN_MLR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26669_CD4_VS_CD8_TCELL_IN_MLR_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus the untreated CD8 T cells."} {"geneset":"GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies."} {"geneset":"GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies."} {"geneset":"GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] effector memory T cells."} {"geneset":"GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] effector memory T cells."} {"geneset":"GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] central memory T cells."} {"geneset":"GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] central memory T cells."} {"geneset":"GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_UP","description":"Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] CXCR5+ [GeneID=643] T cells."} {"geneset":"GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_DN","description":"Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] CXCR5+ [GeneID=643] T cells."} {"geneset":"GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] effector memory T cells versus CD4 [GeneID=920] central memory T cells."} {"geneset":"GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] effector memory T cells versus CD4 [GeneID=920] central memory T cells."} {"geneset":"GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] effector memory T cells versus CD4 [GeneID=920] CXCR5+ [GeneID=643] T cells."} {"geneset":"GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] effector memory T cells versus CD4 [GeneID=920] CXCR5+ [GeneID=643] T cells."} {"geneset":"GSE26928_CENTR_MEMORY_VS_CXCR5_POS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_CENTR_MEMORY_VS_CXCR5_POS_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] central memory T cells versus CD4 [GeneID=920] CXCR5+ [GeneID=643] T cells."} {"geneset":"GSE26928_CENTR_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26928_CENTR_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] central memory T cells versus CD4 [GeneID=920] CXCR5+ [GeneID=643] T cells."} {"geneset":"GSE2706_UNSTIM_VS_2H_R848_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_2H_R848_DC_UP","description":"Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with R848 for 2 h."} {"geneset":"GSE2706_UNSTIM_VS_2H_R848_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_2H_R848_DC_DN","description":"Genes down-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with R848 for 2 h."} {"geneset":"GSE2706_UNSTIM_VS_8H_R848_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_8H_R848_DC_UP","description":"Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with R848 for 8 h."} {"geneset":"GSE2706_UNSTIM_VS_8H_R848_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_8H_R848_DC_DN","description":"Genes down-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with R848 for 8 h."} {"geneset":"GSE2706_UNSTIM_VS_2H_LPS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_2H_LPS_DC_UP","description":"Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) for 2 h."} {"geneset":"GSE2706_UNSTIM_VS_2H_LPS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_2H_LPS_DC_DN","description":"Genes down-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) for 2 h."} {"geneset":"GSE2706_UNSTIM_VS_8H_LPS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_8H_LPS_DC_UP","description":"Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) for 8 h."} {"geneset":"GSE2706_UNSTIM_VS_8H_LPS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_8H_LPS_DC_DN","description":"Genes down-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) for 8 h."} {"geneset":"GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_UP","description":"Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 2 h."} {"geneset":"GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN","description":"Genes down-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 2 h."} {"geneset":"GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP","description":"Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h."} {"geneset":"GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN","description":"Genes down-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h."} {"geneset":"GSE2706_R848_VS_LPS_2H_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_R848_VS_LPS_2H_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulated with LPS (TLR4 agonist) for 2 h."} {"geneset":"GSE2706_R848_VS_LPS_2H_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_R848_VS_LPS_2H_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulated with LPS (TLR4 agonist) for 2 h."} {"geneset":"GSE2706_R848_VS_LPS_8H_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_R848_VS_LPS_8H_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with R848 at 8 h versus DCs stimulated with LPS (TLR4 agonist) for 8 h."} {"geneset":"GSE2706_R848_VS_LPS_8H_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_R848_VS_LPS_8H_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with R848 at 8 h versus DCs stimulated with LPS (TLR4 agonist) for 8 h."} {"geneset":"GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 2 h."} {"geneset":"GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 2 h."} {"geneset":"GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with R848 at 8 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h."} {"geneset":"GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with R848 at 8 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h."} {"geneset":"GSE2706_LPS_VS_R848_AND_LPS_2H_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_LPS_VS_R848_AND_LPS_2H_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 2 h."} {"geneset":"GSE2706_LPS_VS_R848_AND_LPS_2H_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_LPS_VS_R848_AND_LPS_2H_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 2 h."} {"geneset":"GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h."} {"geneset":"GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h."} {"geneset":"GSE2706_2H_VS_8H_R848_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_2H_VS_8H_R848_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulatd with R848 for 8 h."} {"geneset":"GSE2706_2H_VS_8H_R848_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_2H_VS_8H_R848_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulatd with R848 for 8 h."} {"geneset":"GSE2706_2H_VS_8H_LPS_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_2H_VS_8H_LPS_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DCs stimulated with LPS (TLR4 agonist) at 8 h."} {"geneset":"GSE2706_2H_VS_8H_LPS_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_2H_VS_8H_LPS_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DCs stimulated with LPS (TLR4 agonist) at 8 h."} {"geneset":"GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulated with LPS (TLR4 agonist) at 8 h."} {"geneset":"GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulated with LPS (TLR4 agonist) at 8 h."} {"geneset":"GSE27786_LSK_VS_LIN_NEG_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_LIN_NEG_CELL_UP","description":"Genes up-regulated in comparison of LSK versus lineage negative cells."} {"geneset":"GSE27786_LSK_VS_LIN_NEG_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_LIN_NEG_CELL_DN","description":"Genes down-regulated in comparison of LSK versus lineage negative cells."} {"geneset":"GSE27786_LSK_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_BCELL_UP","description":"Genes up-regulated in comparison of LSK versus B cells."} {"geneset":"GSE27786_LSK_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_BCELL_DN","description":"Genes down-regulated in comparison of LSK versus B cells."} {"geneset":"GSE27786_LSK_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_CD4_TCELL_UP","description":"Genes up-regulated in comparison of LSK versus CD4 [GeneID=920] T cells."} {"geneset":"GSE27786_LSK_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_CD4_TCELL_DN","description":"Genes down-regulated in comparison of LSK versus CD4 [GeneID=920] T cells."} {"geneset":"GSE27786_LSK_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_CD8_TCELL_UP","description":"Genes up-regulatd in comparison of LSK versus CD8 T cells."} {"geneset":"GSE27786_LSK_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_CD8_TCELL_DN","description":"Genes down-regulatd in comparison of LSK versus CD8 T cells."} {"geneset":"GSE27786_LSK_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_NKCELL_UP","description":"Genes up-regulated in comparison of LSK versus NK cells."} {"geneset":"GSE27786_LSK_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_NKCELL_DN","description":"Genes down-regulated in comparison of LSK versus NK cells."} {"geneset":"GSE27786_LSK_VS_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_NKTCELL_UP","description":"Genes up-regulated in comparison of LSK versus NKT cells."} {"geneset":"GSE27786_LSK_VS_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_NKTCELL_DN","description":"Genes down-regulated in comparison of LSK versus NKT cells."} {"geneset":"GSE27786_LSK_VS_ERYTHROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_ERYTHROBLAST_UP","description":"Genes up-regulated in comparison of LSK versus erythroblasts."} {"geneset":"GSE27786_LSK_VS_ERYTHROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_ERYTHROBLAST_DN","description":"Genes down-regulated in comparison of LSK versus erythroblasts."} {"geneset":"GSE27786_LSK_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of LSK versus neutrophils."} {"geneset":"GSE27786_LSK_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of LSK versus neutrophils."} {"geneset":"GSE27786_LSK_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of LSK versus monocyte macrophages."} {"geneset":"GSE27786_LSK_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LSK_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of LSK versus monocyte macrophages."} {"geneset":"GSE27786_LIN_NEG_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_BCELL_UP","description":"Genes up-regulated in comparison of lineage negative versus B cells."} {"geneset":"GSE27786_LIN_NEG_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_BCELL_DN","description":"Genes down-regulated in comparison of lineage negative versus B cells."} {"geneset":"GSE27786_LIN_NEG_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_CD4_TCELL_UP","description":"Genes up-regulated in comparison of lineage negative versus CD4 [GeneID=920] T cells."} {"geneset":"GSE27786_LIN_NEG_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_CD4_TCELL_DN","description":"Genes down-regulated in comparison of lineage negative versus CD4 [GeneID=920] T cells."} {"geneset":"GSE27786_LIN_NEG_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_CD8_TCELL_UP","description":"Genes up-regulated in comparison of lineage negative versus CD8 T cells."} {"geneset":"GSE27786_LIN_NEG_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_CD8_TCELL_DN","description":"Genes down-regulated in comparison of lineage negative versus CD8 T cells."} {"geneset":"GSE27786_LIN_NEG_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_NKCELL_UP","description":"Genes up-regulated in comparison of lineage negative versus NK cells."} {"geneset":"GSE27786_LIN_NEG_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_NKCELL_DN","description":"Genes down-regulated in comparison of lineage negative versus NK cells."} {"geneset":"GSE27786_LIN_NEG_VS_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_NKTCELL_UP","description":"Genes up-regulated in comparison of lineage negative versus NKT cells."} {"geneset":"GSE27786_LIN_NEG_VS_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_NKTCELL_DN","description":"Genes down-regulated in comparison of lineage negative versus NKT cells."} {"geneset":"GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP","description":"Genes up-regulated in comparison of lineage negative versus erythroblasts."} {"geneset":"GSE27786_LIN_NEG_VS_ERYTHROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_ERYTHROBLAST_DN","description":"Genes down-regulated in comparison of lineage negative versus erythroblasts."} {"geneset":"GSE27786_LIN_NEG_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of lineage negative versus neutrophils."} {"geneset":"GSE27786_LIN_NEG_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of lineage negative versus neutrophils."} {"geneset":"GSE27786_LIN_NEG_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of lineage negative versus monocyte macrophages."} {"geneset":"GSE27786_LIN_NEG_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_LIN_NEG_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of lineage negative versus monocyte macrophages."} {"geneset":"GSE27786_BCELL_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_CD4_TCELL_UP","description":"Genes up-regulated in comparison of B cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE27786_BCELL_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_CD4_TCELL_DN","description":"Genes down-regulated in comparison of B cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE27786_BCELL_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_CD8_TCELL_UP","description":"Genes up-regulated in comparison of B cells versus CD8 T cells."} {"geneset":"GSE27786_BCELL_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_CD8_TCELL_DN","description":"Genes down-regulated in comparison of B cells versus CD8 T cells."} {"geneset":"GSE27786_BCELL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of B cells versus NK cells."} {"geneset":"GSE27786_BCELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of B cells versus NK cells."} {"geneset":"GSE27786_BCELL_VS_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_NKTCELL_UP","description":"Genes up-regulated in comparison of B cells versus NKT cells."} {"geneset":"GSE27786_BCELL_VS_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_NKTCELL_DN","description":"Genes down-regulated in comparison of B cells versus NKT cells."} {"geneset":"GSE27786_BCELL_VS_ERYTHROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_ERYTHROBLAST_UP","description":"Genes up-regulated in comparison of B cells versus erythroblasts."} {"geneset":"GSE27786_BCELL_VS_ERYTHROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_ERYTHROBLAST_DN","description":"Genes down-regulated in comparison of B cells versus erythroblasts."} {"geneset":"GSE27786_BCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of B cells versus neutrophils."} {"geneset":"GSE27786_BCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of B cells versus neutrophils."} {"geneset":"GSE27786_BCELL_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of B cells versus monocyte macrophages."} {"geneset":"GSE27786_BCELL_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_BCELL_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of B cells versus monocyte macrophages."} {"geneset":"GSE27786_CD4_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_VS_CD8_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells versus CD8 T cells."} {"geneset":"GSE27786_CD4_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_VS_CD8_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells versus CD8 T cells."} {"geneset":"GSE27786_CD4_TCELL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells versus NK cells."} {"geneset":"GSE27786_CD4_TCELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells versus NK cells."} {"geneset":"GSE27786_CD4_TCELL_VS_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_NKTCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells versus NKT cells."} {"geneset":"GSE27786_CD4_TCELL_VS_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_NKTCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells versus NKT cells."} {"geneset":"GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells versus erythroblasts."} {"geneset":"GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells versus erythroblasts."} {"geneset":"GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells versus neutrophils."} {"geneset":"GSE27786_CD4_TCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells versus neutrophils."} {"geneset":"GSE27786_CD4_TCELL_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells versus monocyte macrophages."} {"geneset":"GSE27786_CD4_TCELL_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD4_TCELL_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells versus monocyte macrophages."} {"geneset":"GSE27786_CD8_TCELL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells versus NK cells."} {"geneset":"GSE27786_CD8_TCELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells versus NK cells."} {"geneset":"GSE27786_CD8_TCELL_VS_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_NKTCELL_UP","description":"Genes up-regulated in comparison of CD8 T cells versus NKT cells."} {"geneset":"GSE27786_CD8_TCELL_VS_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_NKTCELL_DN","description":"Genes down-regulated in comparison of CD8 T cells versus NKT cells."} {"geneset":"GSE27786_CD8_TCELL_VS_ERYTHROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_ERYTHROBLAST_UP","description":"Genes up-regulated in comparison of CD8 T cells versus erythroblasts."} {"geneset":"GSE27786_CD8_TCELL_VS_ERYTHROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_ERYTHROBLAST_DN","description":"Genes down-regulated in comparison of CD8 T cells versus erythroblasts."} {"geneset":"GSE27786_CD8_TCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of CD8 T cells versus neutrophils."} {"geneset":"GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of CD8 T cells versus neutrophils."} {"geneset":"GSE27786_CD8_TCELL_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of CD8 T cells versus monocyte macrophages."} {"geneset":"GSE27786_CD8_TCELL_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_CD8_TCELL_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of CD8 T cells versus monocyte macrophages."} {"geneset":"GSE27786_NKCELL_VS_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKCELL_VS_NKTCELL_UP","description":"Genes up-regulated in comparison of NK cells versus NKT cells."} {"geneset":"GSE27786_NKCELL_VS_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKCELL_VS_NKTCELL_DN","description":"Genes down-regulated in comparison of NK cells versus NKT cells."} {"geneset":"GSE27786_NKCELL_VS_ERYTHROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKCELL_VS_ERYTHROBLAST_UP","description":"Genes up-regulated in comparison of NK cells versus erythroblasts."} {"geneset":"GSE27786_NKCELL_VS_ERYTHROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKCELL_VS_ERYTHROBLAST_DN","description":"Genes down-regulated in comparison of NK cells versus erythroblasts."} {"geneset":"GSE27786_NKCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of NK cells versus neutrophils."} {"geneset":"GSE27786_NKCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of NK cells versus neutrophils."} {"geneset":"GSE27786_NKCELL_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKCELL_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of NK cells versus monocyte macrophages."} {"geneset":"GSE27786_NKCELL_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKCELL_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of NK cells versus monocyte macrophages."} {"geneset":"GSE27786_NKTCELL_VS_ERYTHROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKTCELL_VS_ERYTHROBLAST_UP","description":"Genes up-regulated in comparison of NKT cells versus erythroblasts."} {"geneset":"GSE27786_NKTCELL_VS_ERYTHROBLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKTCELL_VS_ERYTHROBLAST_DN","description":"Genes down-regulated in comparison of NKT cells versus erythroblasts."} {"geneset":"GSE27786_NKTCELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKTCELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of NKT cells versus neutrophils."} {"geneset":"GSE27786_NKTCELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKTCELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of NKT cells versus neutrophils."} {"geneset":"GSE27786_NKTCELL_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKTCELL_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of NKT cells versus monocyte macrophages."} {"geneset":"GSE27786_NKTCELL_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NKTCELL_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of NKT cells versus monocyte macrophages."} {"geneset":"GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of erythroblasts versus neutrophils."} {"geneset":"GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of erythroblasts versus neutrophils."} {"geneset":"GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of erythroblasts versus monocyte macrophages."} {"geneset":"GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of erythroblasts versus monocyte macrophages."} {"geneset":"GSE27786_NEUTROPHIL_VS_MONO_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NEUTROPHIL_VS_MONO_MAC_UP","description":"Genes up-regulated in comparison of neutrophils versus monocyte macrophages."} {"geneset":"GSE27786_NEUTROPHIL_VS_MONO_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27786_NEUTROPHIL_VS_MONO_MAC_DN","description":"Genes down-regulated in comparison of neutrophils versus monocyte macrophages."} {"geneset":"GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_UP","description":"Genes up-regulated in comparison of naive follicular B cells versus early germinal center (GC) B cells."} {"geneset":"GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_DN","description":"Genes down-regulated in comparison of naive follicular B cells versus early germinal center (GC) B cells."} {"geneset":"GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_UP","description":"Genes up-regulated in comparison of follicular B cells versus late germinal center (GC) B cells."} {"geneset":"GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN","description":"Genes down-regulated in comparison of follicular B cells versus late germinal center (GC) B cells."} {"geneset":"GSE28237_EARLY_VS_LATE_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28237_EARLY_VS_LATE_GC_BCELL_UP","description":"Genes up-regulated in comparison of early germinal center (GC) B cells versus late GC B cells."} {"geneset":"GSE28237_EARLY_VS_LATE_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28237_EARLY_VS_LATE_GC_BCELL_DN","description":"Genes down-regulated in comparison of early germinal center (GC) B cells versus late GC B cells."} {"geneset":"GSE2826_WT_VS_XID_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2826_WT_VS_XID_BCELL_UP","description":"Genes up-regulated in comparison of primary splenic B cells from wild type mice versus those from Xid mice."} {"geneset":"GSE2826_WT_VS_XID_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2826_WT_VS_XID_BCELL_DN","description":"Genes down-regulated in comparison of primary splenic B cells from wild type mice versus those from Xid mice."} {"geneset":"GSE2826_WT_VS_BTK_KO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2826_WT_VS_BTK_KO_BCELL_UP","description":"Genes up-regulated in comparison of primary splenic B cells from wild type mice versus those from BTK [GeneID=695] knockout mice."} {"geneset":"GSE2826_WT_VS_BTK_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2826_WT_VS_BTK_KO_BCELL_DN","description":"Genes down-regulated in comparison of primary splenic B cells from wild type mice versus those from BTK [GeneID=695] knockout mice."} {"geneset":"GSE2826_XID_VS_BTK_KO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2826_XID_VS_BTK_KO_BCELL_UP","description":"Genes up-regulated in comparison of primary splenic B cells from Xid mice versus those from BTK [GeneID=695] knockout mice."} {"geneset":"GSE2826_XID_VS_BTK_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2826_XID_VS_BTK_KO_BCELL_DN","description":"Genes down-regulated in comparison of primary splenic B cells from Xid mice versus those from BTK [GeneID=695] knockout mice."} {"geneset":"GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus that after the vaccination"} {"geneset":"GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus that after the vaccination"} {"geneset":"GSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those from day 3 post-vaccination."} {"geneset":"GSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those from day 3 post-vaccination."} {"geneset":"GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those from day 7 post-vaccination."} {"geneset":"GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those from day 7 post-vaccination."} {"geneset":"GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee at day 3 post-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee at day 3 post-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29615_CTRL_VS_DAY3_LAIV_IFLU_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29615_CTRL_VS_DAY3_LAIV_IFLU_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccinee pre-vaccination versus those at day 3 post-vaccination."} {"geneset":"GSE29615_CTRL_VS_DAY3_LAIV_IFLU_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29615_CTRL_VS_DAY3_LAIV_IFLU_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccinee pre-vaccination versus those at day 3 post-vaccination."} {"geneset":"GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccine pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccine pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29615_DAY3_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29615_DAY3_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccinee at day 3 post-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29615_DAY3_VS_DAY7_LAIV_FLU_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29615_DAY3_VS_DAY7_LAIV_FLU_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccinee at day 3 post-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29615_CTRL_VS_LAIV_FLU_VACCINE_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29615_CTRL_VS_LAIV_FLU_VACCINE_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those post-vaccination."} {"geneset":"GSE29615_CTRL_VS_LAIV_FLU_VACCINE_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29615_CTRL_VS_LAIV_FLU_VACCINE_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those post-vaccination."} {"geneset":"GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee before vaccination versus that after the vaccination."} {"geneset":"GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee before vaccination versus that after the vaccination."} {"geneset":"GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those at day 3 post-vaccination."} {"geneset":"GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those at day 3 post-vaccination."} {"geneset":"GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee at day 3 post-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee at day 3 post-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_BCELL_VS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_MONOCYTE_UP","description":"Genes up-regulated in comparison of B cells versus monocytes."} {"geneset":"GSE29618_BCELL_VS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_MONOCYTE_DN","description":"Genes down-regulated in comparison of B cells versus monocytes."} {"geneset":"GSE29618_BCELL_VS_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_PDC_UP","description":"Genes up-regulated in comparison of B cells versus plasmacytoid dendritic cells (pDC) ."} {"geneset":"GSE29618_BCELL_VS_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_PDC_DN","description":"Genes down-regulated in comparison of B cells versus plasmacytoid dendritic cells (pDC) ."} {"geneset":"GSE29618_BCELL_VS_MDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_MDC_UP","description":"Genes up-regulated in comparison of B cells versus myeloid dendritic cells (mDC)."} {"geneset":"GSE29618_BCELL_VS_MDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_MDC_DN","description":"Genes down-regulated in comparison of B cells versus myeloid dendritic cells (mDC)."} {"geneset":"GSE29618_MONOCYTE_VS_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_MONOCYTE_VS_PDC_UP","description":"Genes up-regulated in comparison of monocytes versus plasmacytoid dendritic cells (pDC)."} {"geneset":"GSE29618_MONOCYTE_VS_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_MONOCYTE_VS_PDC_DN","description":"Genes down-regulated in comparison of monocytes versus plasmacytoid dendritic cells (pDC)."} {"geneset":"GSE29618_MONOCYTE_VS_MDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_MONOCYTE_VS_MDC_UP","description":"Genes up-regulated in comparison of monocytes versus myeloid dendritic cells (mDC)."} {"geneset":"GSE29618_MONOCYTE_VS_MDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_MONOCYTE_VS_MDC_DN","description":"Genes down-regulated in comparison of monocytes versus myeloid dendritic cells (mDC)."} {"geneset":"GSE29618_PDC_VS_MDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PDC_VS_MDC_UP","description":"Genes up-regulated in comparison of plasmacytoid dendritic cells (DC) versus myeloid DCs."} {"geneset":"GSE29618_PDC_VS_MDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PDC_VS_MDC_DN","description":"Genes down-regulated in comparison of plasmacytoid dendritic cells (DC) versus myeloid DCs."} {"geneset":"GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP","description":"Genes up-regulated in comparison of B cells from influenza vaccinee at day 7 versus monocytes from influenza vaccinee at day 7."} {"geneset":"GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN","description":"Genes down-regulated in comparison of B cells from influenza vaccinee at day 7 versus monocytes from influenza vaccinee at day 7."} {"geneset":"GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP","description":"Genes up-regulated in comparison of B cells from influenza vaccinee at day 7 post-vaccination versus plasmacytoid dendritic cells (pDC) at day 7 post-vaccination."} {"geneset":"GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN","description":"Genes down-regulated in comparison of B cells from influenza vaccinee at day 7 post-vaccination versus plasmacytoid dendritic cells (pDC) at day 7 post-vaccination."} {"geneset":"GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP","description":"Genes up-regulated in comparison of B cells from influenza vaccinee at day 7 post-vaccination versus myeloid dendritic cells (mDC) at day 7 post-vaccination."} {"geneset":"GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN","description":"Genes down-regulated in comparison of B cells from influenza vaccinee at day 7 post-vaccination versus myeloid dendritic cells (mDC) at day 7 post-vaccination."} {"geneset":"GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP","description":"Genes up-regulated in comparison of monocytes from influenza vaccinee at day 7 post-vaccination versus plasmacytoid dendritic cells (mDC) at day 7 post-vaccination."} {"geneset":"GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN","description":"Genes down-regulated in comparison of monocytes from influenza vaccinee at day 7 post-vaccination versus plasmacytoid dendritic cells (mDC) at day 7 post-vaccination."} {"geneset":"GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP","description":"Genes up-regulated in comparison of monocytes from influenza vaccinee at day 7 post-vaccination versus myeloid dendritic cells at day 7 post-vaccination."} {"geneset":"GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_DN","description":"Genes down-regulated in comparison of monocytes from influenza vaccinee at day 7 post-vaccination versus myeloid dendritic cells at day 7 post-vaccination."} {"geneset":"GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP","description":"Genes up-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 7 post-vaccination versus myeloid DCs at day 7 post-vaccination."} {"geneset":"GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN","description":"Genes down-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 7 post-vaccination versus myeloid DCs at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_UP","description":"Genes up-regulated in comparison of B cells from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN","description":"Genes down-regulated in comparison of B cells from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_UP","description":"Genes up-regulated in comparison of plasmacytoid dendritic cells (pDC) from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN","description":"Genes down-regulated in comparison of plasmacytoid dendritic cells (pDC) from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP","description":"Genes up-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 0 versus myeloid DCs at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_DN","description":"Genes down-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 0 versus myeloid DCs at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_UP","description":"Genes up-regulated in comparison of B cells from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_DN","description":"Genes down-regulated in comparison of B cells from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_BCELL_UP","description":"Genes up-regulated in comparison of B cells from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_BCELL_DN","description":"Genes down-regulated in comparison of B cells from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination"} {"geneset":"GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination"} {"geneset":"GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination"} {"geneset":"GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination"} {"geneset":"GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_UP","description":"Genes up-regulated in comparison of plasmacytoid dendritic cells (pDC) from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN","description":"Genes down-regulated in comparison of plasmacytoid dendritic cells (pDC) from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP","description":"Genes up-regulated in comparison of plasmacytoid dendritic cells (pDC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_DN","description":"Genes down-regulated in comparison of plasmacytoid dendritic cells (pDC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_UP","description":"Genes up-regulated in comparison of myeloid dendritic cells (mDC) from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_DN","description":"Genes down-regulated in comparison of myeloid dendritic cells (mDC) from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MDC_UP","description":"Genes up-regulated in comparison of myeloid dendritic cells (mDC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MDC_DN","description":"Genes down-regulated in comparison of myeloid dendritic cells (mDC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination."} {"geneset":"GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_UP","description":"Genes up-regulated in comparison of B cells from LAIV influenza vaccinee at day 7 post-vaccination versus those from TIV influenza vaccinee at day 7 post-vaccination."} {"geneset":"GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_DN","description":"Genes down-regulated in comparison of B cells from LAIV influenza vaccinee at day 7 post-vaccination versus those from TIV influenza vaccinee at day 7 post-vaccination."} {"geneset":"GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7."} {"geneset":"GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7."} {"geneset":"GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP","description":"Genes up-regulated in comparison of plasmacytoid dendritic cells from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7."} {"geneset":"GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_DN","description":"Genes down-regulated in comparison of plasmacytoid dendritic cells from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7."} {"geneset":"GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP","description":"Genes up-regulated in comparison of myeloid dendritic cells from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7."} {"geneset":"GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_DN","description":"Genes down-regulated in comparison of myeloid dendritic cells from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7."} {"geneset":"GSE30083_SP1_VS_SP2_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP1_VS_SP2_THYMOCYTE_UP","description":"Genes up-regulated in comparison of SP1 thymocytes versus SP2 thymocytes."} {"geneset":"GSE30083_SP1_VS_SP2_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP1_VS_SP2_THYMOCYTE_DN","description":"Genes down-regulated in comparison of SP1 thymocytes versus SP2 thymocytes."} {"geneset":"GSE30083_SP1_VS_SP3_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP1_VS_SP3_THYMOCYTE_UP","description":"Genes up-regulated in comparison of SP1 thymocytes versus SP3 thymocytes."} {"geneset":"GSE30083_SP1_VS_SP3_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP1_VS_SP3_THYMOCYTE_DN","description":"Genes down-regulated in comparison of SP1 thymocytes versus SP3 thymocytes."} {"geneset":"GSE30083_SP1_VS_SP4_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP1_VS_SP4_THYMOCYTE_UP","description":"Genes up-regulated in comparison of SP1 thymocytes versus SP4 thymocytes."} {"geneset":"GSE30083_SP1_VS_SP4_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP1_VS_SP4_THYMOCYTE_DN","description":"Genes down-regulated in comparison of SP1 thymocytes versus SP4 thymocytes."} {"geneset":"GSE30083_SP2_VS_SP3_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP2_VS_SP3_THYMOCYTE_UP","description":"Genes up-regulated in comparison of SP2 thymocytes versus SP3 thymocytes."} {"geneset":"GSE30083_SP2_VS_SP3_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP2_VS_SP3_THYMOCYTE_DN","description":"Genes down-regulated in comparison of SP2 thymocytes versus SP3 thymocytes."} {"geneset":"GSE30083_SP2_VS_SP4_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP2_VS_SP4_THYMOCYTE_UP","description":"Genes up-regulated in comparison of SP2 thymocytes versus SP4 thymocytes."} {"geneset":"GSE30083_SP2_VS_SP4_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP2_VS_SP4_THYMOCYTE_DN","description":"Genes down-regulated in comparison of SP2 thymocytes versus SP4 thymocytes."} {"geneset":"GSE30083_SP3_VS_SP4_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP3_VS_SP4_THYMOCYTE_UP","description":"Genes up-regulated in comparison of SP3 thymocytes versus SP4 thymocytes."} {"geneset":"GSE30083_SP3_VS_SP4_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30083_SP3_VS_SP4_THYMOCYTE_DN","description":"Genes down-regulated in comparison of SP3 thymocytes versus SP4 thymocytes."} {"geneset":"GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of splenic primary CD8 effector T cells at day 8 post-acute infection versus splenic secondary CD8 effector T cells at day 8 post-acute infection."} {"geneset":"GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of splenic primary CD8 effector T cells at day 8 post-acute infection versus splenic secondary CD8 effector T cells at day 8 post-acute infection."} {"geneset":"GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of splenic primary CD8 effector T cells at day 8 post-chronic infection versus splenic secondary CD8 effector T cells at day 8 post-chronic infection."} {"geneset":"GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of splenic primary CD8 effector T cells at day 8 post-chronic infection versus splenic secondary CD8 effector T cells at day 8 post-chronic infection."} {"geneset":"GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of splenic primary CD8 effector T cells at day 8 post-acute infection versus splenic primary CD8 effector T cells at day 8 post-chronic infection."} {"geneset":"GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of splenic primary CD8 effector T cells at day 8 post-acute infection versus splenic primary CD8 effector T cells at day 8 post-chronic infection."} {"geneset":"GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of splenic secondary CD8 effector T cells at day 8 post-acute infection versus splenic secondary CD8 effector T cells at day 8 post-chronic infection."} {"geneset":"GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of splenic secondary CD8 effector T cells at day 8 post-acute infection versus splenic secondary CD8 effector T cells at day 8 post-chronic infection."} {"geneset":"GSE31082_DN_VS_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DN_VS_DP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4- [GeneID=920] CD8- thymocytes versus CD4+ [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE31082_DN_VS_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DN_VS_DP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4- [GeneID=920] CD8- thymocytes versus CD4+ [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE31082_DN_VS_CD4_SP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DN_VS_CD4_SP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4- [GeneID=920] CD8- thymocytes versus CD4+ [GeneID=920] CD8- thymocytes."} {"geneset":"GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4- [GeneID=920] CD8- thymocytes versus CD4+ [GeneID=920] CD8- thymocytes."} {"geneset":"GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4- [GeneID=920] CD8- thymocytes versus CD4- [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4- [GeneID=920] CD8- thymocytes versus CD4- [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4+ [GeneID=920] CD8+ thymocytes versus CD4+ [GeneID=920] CD8- thymocytes."} {"geneset":"GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4+ [GeneID=920] CD8+ thymocytes versus CD4- [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4+ [GeneID=920] CD8+ thymocytes versus CD4- [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE31082_DP_VS_CD8_SP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_DP_VS_CD8_SP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4+ [GeneID=920] CD8+ thymocytes versus CD4- [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP","description":"Genes up-regulated in comparison of CD4+ [GeneID=920] CD8- thymocytes versus CD4- [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN","description":"Genes down-regulated in comparison of CD4+ [GeneID=920] CD8- thymocytes versus CD4- [GeneID=920] CD8+ thymocytes."} {"geneset":"GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells versus naive CD8 T cells."} {"geneset":"GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells versus naive CD8 T cells."} {"geneset":"GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_UP","description":"Genes up-regulated in comparison of memory CD8 T cells treated with IL7 [GeneID=3574] versus naive CD8 T cells treated with IL7 [GeneID=3574]."} {"geneset":"GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_DN","description":"Genes down-regulated in comparison of memory CD8 T cells treated with IL7 [GeneID=3574] versus naive CD8 T cells treated with IL7 [GeneID=3574]."} {"geneset":"GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_UP","description":"Genes up-regulated in comparison of memory CD8 T cells treated with IL4 [GeneID=3565] and IL7 [GeneID=3574] versus naive CD8 T cells treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]."} {"geneset":"GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_DN","description":"Genes down-regulated in comparison of memory CD8 T cells treated with IL4 [GeneID=3565] and IL7 [GeneID=3574] versus naive CD8 T cells treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]."} {"geneset":"GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells versus those treated with IL7 [GeneID=3574]."} {"geneset":"GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells versus those treated with IL7 [GeneID=3574]."} {"geneset":"GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells versus those treated with IL4 [GeneID=3565]."} {"geneset":"GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells versus those treated with IL4 [GeneID=3565]."} {"geneset":"GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells versus those treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]."} {"geneset":"GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells versus those treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]."} {"geneset":"GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]."} {"geneset":"GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]."} {"geneset":"GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of memory CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565]."} {"geneset":"GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of memory CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565]."} {"geneset":"GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]."} {"geneset":"GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]."} {"geneset":"GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_UP","description":"Genes up-regulated in comparison of untreated CD8+ dendritic cells (DC) at 4 h versus those treated with IFNG [GeneID=3458] at 4 h."} {"geneset":"GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN","description":"Genes down-regulated in comparison of untreated CD8+ dendritic cells (DC) at 4 h versus those treated with IFNG [GeneID=3458] at 4 h."} {"geneset":"GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP","description":"Genes up-regulated in comparison of untreated CD8+ dendritic cells (DC) at 16 h versus those treated with IFNG [GeneID=31658] at 16 h."} {"geneset":"GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN","description":"Genes down-regulated in comparison of untreated CD8+ dendritic cells (DC) at 16 h versus those treated with IFNG [GeneID=31658] at 16 h."} {"geneset":"GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP","description":"Genes up-regulated in comparison of untreated CD8+ dendritic cells (DC) at 4 h versus those treated with IFNG [GeneID=3458] at 16 h."} {"geneset":"GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN","description":"Genes down-regulated in comparison of untreated CD8+ dendritic cells (DC) at 4 h versus those treated with IFNG [GeneID=3458] at 16 h."} {"geneset":"GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_UP","description":"Genes up-regulated in comparison of TCF7 [GeneID=6932] deficient early thymic progenitors versus the TCF7 [GeneID=6932] sufficient ones."} {"geneset":"GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_DN","description":"Genes down-regulated in comparison of TCF7 [GeneID=6932] deficient early thymic progenitors versus the TCF7 [GeneID=6932] sufficient ones."} {"geneset":"GSE339_CD4POS_VS_CD8POS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD4POS_VS_CD8POS_DC_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD8 DCs."} {"geneset":"GSE339_CD4POS_VS_CD8POS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD4POS_VS_CD8POS_DC_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD8 DCs."} {"geneset":"GSE339_CD4POS_VS_CD4CD8DN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD4POS_VS_CD4CD8DN_DC_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_CD4POS_VS_CD4CD8DN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD4POS_VS_CD4CD8DN_DC_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_CD8POS_VS_CD4CD8DN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD8POS_VS_CD4CD8DN_DC_UP","description":"Genes up-regulated in comparison of CD8 dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_CD8POS_VS_CD4CD8DN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD8POS_VS_CD4CD8DN_DC_DN","description":"Genes down-regulated in comparison of CD8 dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD8 DCs."} {"geneset":"GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD8 DCs."} {"geneset":"GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP","description":"Genes up-regulated in comparison of CD8 dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN","description":"Genes down-regulated in comparison of CD8 dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_UP","description":"Genes up-regulated in comparison of ex vivo CD4 [GeneID=920] dendritic cells (DC) versus cultured CD4 [GeneID=920] DCs."} {"geneset":"GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN","description":"Genes down-regulated in comparison of ex vivo CD4 [GeneID=920] dendritic cells (DC) versus cultured CD4 [GeneID=920] DCs."} {"geneset":"GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_UP","description":"Genes up-regulated in comparison of ex vivo CD8 dendritic cells versus cultured CD8 DCs."} {"geneset":"GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN","description":"Genes down-regulated in comparison of ex vivo CD8 dendritic cells versus cultured CD8 DCs."} {"geneset":"GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP","description":"Genes up-regulated in comparison of ex vivo CD4- [GeneID=920] CD8- dendritic cells (DC) versus cultured CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN","description":"Genes down-regulated in comparison of ex vivo CD4- [GeneID=920] CD8- dendritic cells (DC) versus cultured CD4- [GeneID=920] CD8- DCs."} {"geneset":"GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from infanct with acute RSV infection."} {"geneset":"GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from infanct with acute RSV infection."} {"geneset":"GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from infanct with acute influenza infection."} {"geneset":"GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from infanct with acute influenza infection."} {"geneset":"GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from infancts with acute RSV infection versus PBMCs from infants with acute influenza infection."} {"geneset":"GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from infancts with acute RSV infection versus PBMCs from infants with acute influenza infection."} {"geneset":"GSE360_CTRL_VS_L_DONOVANI_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_L_DONOVANI_DC_UP","description":"Genes up-regulated in untreated dendritic cells (DC) versus DCs exposed to parasite L. donovani."} {"geneset":"GSE360_CTRL_VS_L_DONOVANI_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_L_DONOVANI_DC_DN","description":"Genes down-regulated in untreated dendritic cells (DC) versus DCs exposed to parasite L. donovani."} {"geneset":"GSE360_CTRL_VS_L_MAJOR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_L_MAJOR_DC_UP","description":"Genes up-regulated in untreated dendritic cells (DC) versus DCs exposed to parasite L. major."} {"geneset":"GSE360_CTRL_VS_L_MAJOR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_L_MAJOR_DC_DN","description":"Genes down-regulated in untreated dendritic cells (DC) versus DCs exposed to parasite L. major."} {"geneset":"GSE360_CTRL_VS_T_GONDII_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_T_GONDII_DC_UP","description":"Genes up-regulated in untreated dendritic cells (DC) versus DCs exposed to parasite Toxoplasma gondii."} {"geneset":"GSE360_CTRL_VS_T_GONDII_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_T_GONDII_DC_DN","description":"Genes down-regulated in untreated dendritic cells (DC) versus DCs exposed to parasite Toxoplasma gondii."} {"geneset":"GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) versus DCs exposed to B. malayi (50 worms/well)."} {"geneset":"GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) versus DCs exposed to B. malayi (50 worms/well)."} {"geneset":"GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) versus DCs exposed to B. malayi (5 worms/well)."} {"geneset":"GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) versus DCs exposed to B. malayi (5 worms/well)."} {"geneset":"GSE360_CTRL_VS_M_TUBERCULOSIS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_M_TUBERCULOSIS_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) versus DCs exposed to M.tuberculosis."} {"geneset":"GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) versus DCs exposed to M.tuberculosis."} {"geneset":"GSE360_CTRL_VS_L_DONOVANI_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_L_DONOVANI_MAC_UP","description":"Genes up-regulated in comparison of macrophages versus macrophages exposed to L.donovani."} {"geneset":"GSE360_CTRL_VS_L_DONOVANI_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_L_DONOVANI_MAC_DN","description":"Genes down-regulated in comparison of macrophages versus macrophages exposed to L.donovani."} {"geneset":"GSE360_CTRL_VS_L_MAJOR_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_L_MAJOR_MAC_UP","description":"Genes up-regulated in comparison of macrophages versus macrophages exposed to L. major."} {"geneset":"GSE360_CTRL_VS_L_MAJOR_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_L_MAJOR_MAC_DN","description":"Genes down-regulated in comparison of macrophages versus macrophages exposed to L. major."} {"geneset":"GSE360_CTRL_VS_T_GONDII_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_T_GONDII_MAC_UP","description":"Genes up-regulated in comparison of macrophages versus macrophages exposed to T. gondii."} {"geneset":"GSE360_CTRL_VS_T_GONDII_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_T_GONDII_MAC_DN","description":"Genes down-regulated in comparison of macrophages versus macrophages exposed to T. gondii."} {"geneset":"GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP","description":"Genes up-regulated in comparison of macrophages versus macrophages exposed to B. malayi (50 worms/well)."} {"geneset":"GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_DN","description":"Genes down-regulated in comparison of macrophages versus macrophages exposed to B. malayi (50 worms/well)."} {"geneset":"GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_UP","description":"Genes up-regulated in comparison of macrophages versus macrophages exposed to B. malayi (5 worms/well)."} {"geneset":"GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_DN","description":"Genes down-regulated in comparison of macrophages versus macrophages exposed to B. malayi (5 worms/well)."} {"geneset":"GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_UP","description":"Genes up-regulated in 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{"geneset":"GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to 5 worm/well B. malayi versus macrophages exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to 5 worm/well B. malayi versus macrophages exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_DC_VS_MAC_M_TUBERCULOSIS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_DC_VS_MAC_M_TUBERCULOSIS_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to M. tuberculosis versus macrophages exposed to L. major."} {"geneset":"GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to M. tuberculosis versus macrophages exposed to L. major."} {"geneset":"GSE360_L_DONOVANI_VS_L_MAJOR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_L_MAJOR_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to L. major."} {"geneset":"GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to L. major."} {"geneset":"GSE360_L_DONOVANI_VS_T_GONDII_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_T_GONDII_DC_UP","description":"Genes up-regulated in 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{"geneset":"GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to 5 worm/well B. malayi."} {"geneset":"GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to 5 worm/well B. malayi."} {"geneset":"GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to M. tuberculosis."} {"geneset":"GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to M. tuberculosis."} {"geneset":"GSE360_L_MAJOR_VS_T_GONDII_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_T_GONDII_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to L. major versus DCs exposed to T. gondii."} {"geneset":"GSE360_L_MAJOR_VS_T_GONDII_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_T_GONDII_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to L. major versus DCs exposed to T. gondii."} {"geneset":"GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP","description":"Genes 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{"geneset":"GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to 50 worms/well B. malayi."} {"geneset":"GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to M. tuberculosis."} {"geneset":"GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to M. tuberculosis."} {"geneset":"GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to 50 worms/well B. malayi versus those exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to 50 worms/well B. malayi versus those exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to 50 worms/well B. malayi versus DC exposed to M. tuberculosis"} {"geneset":"GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to 50 worms/well B. malayi versus DC exposed to M. tuberculosis"} {"geneset":"GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) exposed to 5 worms/well B. malayi versus DC exposed to M. tuberculosis"} {"geneset":"GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) exposed to 5 worms/well B. malayi versus DC exposed to M. tuberculosis"} {"geneset":"GSE360_L_DONOVANI_VS_L_MAJOR_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_L_MAJOR_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to L. donovani versus macrophages exposed to L. major."} {"geneset":"GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to L. donovani versus macrophages exposed to L. major."} {"geneset":"GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to L. donovani versus macrophages exposed to T. gondii."} {"geneset":"GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to L. donovani versus macrophages exposed to T. gondii."} {"geneset":"GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP","description":"Genes 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{"geneset":"GSE360_L_MAJOR_VS_T_GONDII_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_T_GONDII_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to T. gondii."} {"geneset":"GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to 50 worms/well B. malayi."} {"geneset":"GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to 50 worms/well B. malayi."} {"geneset":"GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to M. tuberculosis."} {"geneset":"GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to M. tuberculosis."} {"geneset":"GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to T. gondii versus macrophages exposed to 50 worms/well B. malayi."} {"geneset":"GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to T. gondii versus macrophages exposed to 50 worms/well B. malayi."} {"geneset":"GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to T. gondii versus macrophages exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to T. gondii versus macrophages exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to T. gondii versus macrophages exposed to M. tuberculosis."} {"geneset":"GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to T. gondii versus macrophages exposed to M. tuberculosis."} {"geneset":"GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to 50 worms/well B. malayi versus those exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to 50 worms/well B. malayi versus those exposed to 5 worms/well B. malayi."} {"geneset":"GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to 50 worms/well B. malayi versus macrophages exposed to M. tuberculosis."} {"geneset":"GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to 50 worms/well B. malayi versus macrophages exposed to M. tuberculosis."} {"geneset":"GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP","description":"Genes up-regulated in comparison of macrophages exposed to 5 worms/well B. malayi versus macrophages exposed to M. tuberculosis."} {"geneset":"GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN","description":"Genes down-regulated in comparison of macrophages exposed to 5 worms/well B. malayi versus macrophages exposed to M. tuberculosis."} {"geneset":"GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_UP","description":"Genes up-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus eosinophils treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN","description":"Genes down-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus eosinophils treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_UP","description":"Genes up-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus macrophages treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_DN","description":"Genes down-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus macrophages treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP","description":"Genes up-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus neutrophils treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN","description":"Genes down-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus neutrophils treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP","description":"Genes up-regulated in comparison of eosinophils treated with IL25 [GeneID=64806] versus macrophages treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_DN","description":"Genes down-regulated in comparison of eosinophils treated with IL25 [GeneID=64806] versus macrophages treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP","description":"Genes up-regulated in comparison of eosinophils treated with IL25 [GeneID=64806] versus neutrophils treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN","description":"Genes down-regulated in comparison of eosinophils treated with IL25 [GeneID=64806] versus neutrophils treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP","description":"Genes up-regulated in comparison of macrophages treated with IL25 [GeneID=64806] versus neutrophils treated with IL25 [GeneID=64806]."} {"geneset":"GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN","description":"Genes down-regulated in comparison of macrophages treated with IL25 [GeneID=64806] versus neutrophils treated with IL25 [GeneID=64806]."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 16 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 16 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 40 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 40 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 72 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 72 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 16 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 16 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 40 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 40 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 72 h."} {"geneset":"GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 72 h."} {"geneset":"GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated memory CD4 [GeneID=920] T cells from young donors versus those from old donors."} {"geneset":"GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated memory CD4 [GeneID=920] T cells from young donors versus those from old donors."} {"geneset":"GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_UP","description":"Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 16 h versus those from old donors treated with TSST at 16 h."} {"geneset":"GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_DN","description":"Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 16 h versus those from old donors treated with TSST at 16 h."} {"geneset":"GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_UP","description":"Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 40 h versus those from old donors treated with TSST at 40 h."} {"geneset":"GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN","description":"Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 40 h versus those from old donors treated with TSST at 40 h."} {"geneset":"GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_UP","description":"Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 72 h versus those from old donors treated with TSST at 72 h."} {"geneset":"GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN","description":"Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 72 h versus those from old donors treated with TSST at 72 h."} {"geneset":"GSE37416_CTRL_VS_0H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_0H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 0 h."} {"geneset":"GSE37416_CTRL_VS_0H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_0H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 0 h."} {"geneset":"GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 3 h versus PMN treated with F. tularensis vaccine at 3 h."} {"geneset":"GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 3 h versus PMN treated with F. tularensis vaccine at 3 h."} {"geneset":"GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 6 h versus PMN treated with F. tularensis vaccine at 6 h."} {"geneset":"GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 6 h versus PMN treated with F. tularensis vaccine at 6 h."} {"geneset":"GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 12 h versus PMN treated with F. tularensis vaccine at 12 h."} {"geneset":"GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 12 h versus PMN treated with F. tularensis vaccine at 12 h."} {"geneset":"GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 24 h versus PMN treated with F. tularensis vaccine at 24 h."} {"geneset":"GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 24 h versus PMN treated with F. tularensis vaccine at 24 h."} {"geneset":"GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 48 h versus PMN treated with F. tularensis vaccine at 48 h."} {"geneset":"GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 48 h versus PMN treated with F. tularensis vaccine at 48 h."} {"geneset":"GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 3 h."} {"geneset":"GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 3 h."} {"geneset":"GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 6 h."} {"geneset":"GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 6 h."} {"geneset":"GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 12 h."} {"geneset":"GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 12 h."} {"geneset":"GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 24 h."} {"geneset":"GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 24 h."} {"geneset":"GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 48 h."} {"geneset":"GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 48 h."} {"geneset":"GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 12 h versus PMN treated with F. tularensis vaccine at 24 h."} {"geneset":"GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 12 h versus PMN treated with F. tularensis vaccine at 24 h."} {"geneset":"GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 12 h versus PMN treated with F. tularensis vaccine at 48 h."} {"geneset":"GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 12 h versus PMN treated with F. tularensis vaccine at 48 h."} {"geneset":"GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP","description":"Genes up-regulated in comparison of untreated eosinophils versus eosinophils treated with PMA [PubChem=4792] at 2 h."} {"geneset":"GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_DN","description":"Genes down-regulated in comparison of untreated eosinophils versus eosinophils treated with PMA [PubChem=4792] at 2 h."} {"geneset":"GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_UP","description":"Genes up-regulated in comparison of untreated mast cells versus mast cells treated with IgE at 2 h."} {"geneset":"GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_DN","description":"Genes down-regulated in comparison of untreated mast cells versus mast cells treated with IgE at 2 h."} {"geneset":"GSE3982_CTRL_VS_LPS_4H_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_LPS_4H_MAC_UP","description":"Genes up-regulated in comparison of untreated macrophages versus macrophages treated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE3982_CTRL_VS_LPS_4H_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_LPS_4H_MAC_DN","description":"Genes down-regulated in comparison of untreated macrophages versus macrophages treated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of untreated neutrophils versus neutrophils treated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of untreated neutrophils versus neutrophils treated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE3982_CTRL_VS_LPS_48H_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_LPS_48H_DC_UP","description":"Genes up-regulated in comparison of untreated dendritic cells (DC) versus DCs treated with LPS (TLR4 agonist) at 48 h."} {"geneset":"GSE3982_CTRL_VS_LPS_48H_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CTRL_VS_LPS_48H_DC_DN","description":"Genes down-regulated in comparison of untreated dendritic cells (DC) versus DCs treated with LPS (TLR4 agonist) at 48 h."} {"geneset":"GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP","description":"Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells versus Th1 cells."} {"geneset":"GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN","description":"Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells versus Th1 cells."} {"geneset":"GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP","description":"Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells versus Th2 cells."} {"geneset":"GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN","description":"Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells versus Th2 cells."} {"geneset":"GSE3982_MEMORY_CD4_TCELL_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MEMORY_CD4_TCELL_VS_BCELL_UP","description":"Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells versus B cells."} {"geneset":"GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN","description":"Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells versus B cells."} {"geneset":"GSE3982_DC_VS_MAC_LPS_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_DC_VS_MAC_LPS_STIM_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulatd with LPS (TLR4 agonist) at 48 h versus macrophages stimulated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE3982_DC_VS_MAC_LPS_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_DC_VS_MAC_LPS_STIM_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulatd with LPS (TLR4 agonist) at 48 h versus macrophages stimulated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 48 h versus neutrophils stimulated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 48 h versus neutrophils stimulated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_UP","description":"Genes up-regulated in comparison of macrophages stimulated with LPS (TLR4 agonist) at 4 h versus neutrophils stimulated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_DN","description":"Genes down-regulated in comparison of macrophages stimulated with LPS (TLR4 agonist) at 4 h versus neutrophils stimulated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE3982_EOSINOPHIL_VS_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_MAST_CELL_UP","description":"Genes up-regulated in comparison of eosinophils versus mast cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_MAST_CELL_DN","description":"Genes down-regulated in comparison of eosinophils versus mast cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_DC_UP","description":"Genes up-regulated in comparison of eosinophils versus dendritic cells (DC)."} {"geneset":"GSE3982_EOSINOPHIL_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_DC_DN","description":"Genes down-regulated in comparison of eosinophils versus dendritic cells (DC)."} {"geneset":"GSE3982_EOSINOPHIL_VS_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_MAC_UP","description":"Genes up-regulated in comparison of eosinophils versus macrophages."} {"geneset":"GSE3982_EOSINOPHIL_VS_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_MAC_DN","description":"Genes down-regulated in comparison of eosinophils versus macrophages."} {"geneset":"GSE3982_EOSINOPHIL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of eosinophils versus neutrophils."} {"geneset":"GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of eosinophils versus neutrophils."} {"geneset":"GSE3982_EOSINOPHIL_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_BCELL_UP","description":"Genes up-regulated in comparison of eosinophils versus B cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_BCELL_DN","description":"Genes down-regulated in comparison of eosinophils versus B cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_BASOPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_BASOPHIL_UP","description":"Genes up-regulated in comparison of eosinophils versus basophils."} {"geneset":"GSE3982_EOSINOPHIL_VS_BASOPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_BASOPHIL_DN","description":"Genes down-regulated in comparison of eosinophils versus basophils."} {"geneset":"GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of eosinophils versus effector memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of eosinophils versus effector memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of eosinophils versus central memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of eosinophils versus central memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of eosinophils versus NK cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of eosinophils versus NK cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_TH1_UP","description":"Genes up-regulated in comparison of eosinophils versus Th1 cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_TH1_DN","description":"Genes down-regulated in comparison of eosinophils versus Th1 cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_TH2_UP","description":"Genes up-regulated in comparison of eosinophils versus Th2 cells."} {"geneset":"GSE3982_EOSINOPHIL_VS_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EOSINOPHIL_VS_TH2_DN","description":"Genes down-regulated in comparison of eosinophils versus Th2 cells."} {"geneset":"GSE3982_MAST_CELL_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_DC_UP","description":"Genes up-regulated in comparison of mast cells versus dendritic cells (DC)."} {"geneset":"GSE3982_MAST_CELL_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_DC_DN","description":"Genes down-regulated in comparison of mast cells versus dendritic cells (DC)."} {"geneset":"GSE3982_MAST_CELL_VS_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_MAC_UP","description":"Genes up-regulated in comparison of mast cells versus macrophages."} {"geneset":"GSE3982_MAST_CELL_VS_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_MAC_DN","description":"Genes down-regulated in comparison of mast cells versus macrophages."} {"geneset":"GSE3982_MAST_CELL_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison of mast cells versus neutrophils."} {"geneset":"GSE3982_MAST_CELL_VS_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_NEUTROPHIL_DN","description":"Genes down-regulated in comparison of mast cells versus neutrophils."} {"geneset":"GSE3982_MAST_CELL_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_BCELL_UP","description":"Genes up-regulated in comparison of mast cells versus B cells."} {"geneset":"GSE3982_MAST_CELL_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_BCELL_DN","description":"Genes down-regulated in comparison of mast cells versus B cells."} {"geneset":"GSE3982_MAST_CELL_VS_BASOPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_BASOPHIL_UP","description":"Genes up-regulated in comparison of mast cells versus basophils."} {"geneset":"GSE3982_MAST_CELL_VS_BASOPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_BASOPHIL_DN","description":"Genes down-regulated in comparison of mast cells versus basophils."} {"geneset":"GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of mast cells versus effector memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of mast cells versus effector memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of mast cells versus central memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of mast cells versus central memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_MAST_CELL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of mast cells versus NK cells."} {"geneset":"GSE3982_MAST_CELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of mast cells versus NK cells."} {"geneset":"GSE3982_MAST_CELL_VS_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_TH1_UP","description":"Genes up-regulated in comparison of mast cells versus Th1 cells."} {"geneset":"GSE3982_MAST_CELL_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_TH1_DN","description":"Genes down-regulated in comparison of mast cells versus Th1 cells."} {"geneset":"GSE3982_MAST_CELL_VS_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_TH2_UP","description":"Genes up-regulated in comparison of mast cells versus Th2 cells."} {"geneset":"GSE3982_MAST_CELL_VS_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_MAST_CELL_VS_TH2_DN","description":"Genes down-regulated in comparison of mast cells versus Th2 cells."} {"geneset":"GSE3982_DC_VS_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_DC_VS_MAC_UP","description":"Genes up-regulated in comparison of dendritic cells (DC) versus macrophages."} {"geneset":"GSE3982_DC_VS_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_DC_VS_MAC_DN","description":"Genes down-regulated in comparison of dendritic cells (DC) versus macrophages."} {"geneset":"GSE3982_DC_VS_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_DC_VS_NEUTROPHIL_UP","description":"Genes up-regulated in comparison 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{"geneset":"GSE3982_NEUTROPHIL_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_NEUTROPHIL_VS_TH1_DN","description":"Genes down-regulated in comparison of neutrophils versus Th1 cells."} {"geneset":"GSE3982_NEUTROPHIL_VS_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_NEUTROPHIL_VS_TH2_UP","description":"Genes up-regulated in comparison of neutrophils versus Th2 cells."} {"geneset":"GSE3982_NEUTROPHIL_VS_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_NEUTROPHIL_VS_TH2_DN","description":"Genes down-regulated in comparison of neutrophils versus Th2 cells."} {"geneset":"GSE3982_BCELL_VS_BASOPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_BASOPHIL_UP","description":"Genes up-regulated in comparison of B cells versus basophils."} {"geneset":"GSE3982_BCELL_VS_BASOPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_BASOPHIL_DN","description":"Genes 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{"geneset":"GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of B cells versus central memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_BCELL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of B cells versus NK cells."} {"geneset":"GSE3982_BCELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of B cells versus NK cells."} {"geneset":"GSE3982_BCELL_VS_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_TH1_UP","description":"Genes up-regulated in comparison of B cells versus Th1 cells."} {"geneset":"GSE3982_BCELL_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_TH1_DN","description":"Genes down-regulated in comparison of B cells versus Th1 cells."} {"geneset":"GSE3982_BCELL_VS_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_TH2_UP","description":"Genes up-regulated in comparison of B cells versus Th2 cells."} {"geneset":"GSE3982_BCELL_VS_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BCELL_VS_TH2_DN","description":"Genes down-regulated in comparison of B cells versus Th2 cells."} {"geneset":"GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of basophils versus effector memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of basophils versus effector memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in comparison of basophils versus central memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in comparison of basophils versus central memory CD4 [GeneID=920] T cells."} {"geneset":"GSE3982_BASOPHIL_VS_NKCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_BASOPHIL_VS_NKCELL_UP","description":"Genes up-regulated in comparison of 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{"geneset":"GSE3982_EFF_MEMORY_CD4_TCELL_VS_NKCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EFF_MEMORY_CD4_TCELL_VS_NKCELL_DN","description":"Genes down-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus NK cells."} {"geneset":"GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_UP","description":"Genes up-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus Th1 cells."} {"geneset":"GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN","description":"Genes down-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus Th1 cells."} {"geneset":"GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP","description":"Genes up-regulated in comparison of effective 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{"geneset":"GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_UP","description":"Genes up-regulated in comparison of central memory CD4 [GeneID=920] T cells versus Th1 cells."} {"geneset":"GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN","description":"Genes down-regulated in comparison of central memory CD4 [GeneID=920] T cells versus Th1 cells."} {"geneset":"GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP","description":"Genes up-regulated in comparison of central memory CD4 [GeneID=920] T cells versus Th2 cells."} {"geneset":"GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN","description":"Genes down-regulated in comparison of central memory CD4 [GeneID=920] T cells versus Th2 cells."} {"geneset":"GSE3982_NKCELL_VS_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_NKCELL_VS_TH1_UP","description":"Genes up-regulated in comparison of NK cells versus Th1 cells."} {"geneset":"GSE3982_NKCELL_VS_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_NKCELL_VS_TH1_DN","description":"Genes down-regulated in comparison of NK cells versus Th1 cells."} {"geneset":"GSE3982_NKCELL_VS_TH2_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_NKCELL_VS_TH2_UP","description":"Genes up-regulated in comparison of NK cells versus Th2 cells."} {"geneset":"GSE3982_NKCELL_VS_TH2_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3982_NKCELL_VS_TH2_DN","description":"Genes down-regulated in comparison of NK cells versus Th2 cells."} {"geneset":"GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with IL1B [GeneID=3553] and IL6 [GeneID=3569]."} {"geneset":"GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with IL1B [GeneID=3553] and IL6 [GeneID=3569]."} {"geneset":"GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated witl IL1B [GeneID=3553], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with IL1B [GeneID=3553], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with TGFB1 [GeneID=7040] and IL6 [GeneID=3569]."} {"geneset":"GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with TGFB1 [GeneID=7040] and IL6 [GeneID=3569]."} {"geneset":"GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with TGFB1 [GeneID=7040], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with TGFB1 [GeneID=7040], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with TGFB3 [GeneID=7043] IL6 [GeneID=3569]."} {"geneset":"GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with TGFB3 [GeneID=7043] IL6 [GeneID=3569]."} {"geneset":"GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with TGFB3 [GeneID=7043], IL6 [GeneID=3569] and IL32A [GeneID=51561]."} {"geneset":"GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with TGFB3 [GeneID=7043], IL6 [GeneID=3569] and IL32A [GeneID=51561]."} {"geneset":"GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells treated with IL1B [GeneID=3553] and IL6 [GeneID=3569] versus those treated with IL1B [GeneID=3553], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells treated with IL1B [GeneID=3553] and IL6 [GeneID=3569] versus those treated with IL1B [GeneID=3553], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] and IL6 [GeneID=3569] versus those treated with TGFB1 [GeneID=7040], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] and IL6 [GeneID=3569] versus those treated with TGFB1 [GeneID=7040], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB3 [GeneID=7043] and IL6 [GeneID=3569] versus those treated with TGF3B [GeneID=7043], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB3 [GeneID=7043] and IL6 [GeneID=3569] versus those treated with TGF3B [GeneID=7043], IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] versus those treated with TGFB3 [GeneID=7043] and IL6 [GeneID=3569]."} {"geneset":"GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] versus those treated with TGFB3 [GeneID=7043] and IL6 [GeneID=3569]."} {"geneset":"GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] versus those treated with TGFB3 [GeneID=7043] treated with IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] versus those treated with TGFB3 [GeneID=7043] treated with IL6 [GeneID=3569] and IL23A [GeneID=51561]."} {"geneset":"GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP","description":"Genes up-regulated in comparison of control thymocytes versus thymocytes treated with dexamethasone [PubChem=5743]."} {"geneset":"GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_DN","description":"Genes down-regulated in comparison of control thymocytes versus thymocytes treated with dexamethasone [PubChem=5743]."} {"geneset":"GSE5960_TH1_VS_ANERGIC_TH1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5960_TH1_VS_ANERGIC_TH1_UP","description":"Genes up-regulated in comparison of anergy induced CD4 [GeneID=920] T cells versus conventional CD4 [GeneID=920] T cells."} {"geneset":"GSE5960_TH1_VS_ANERGIC_TH1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5960_TH1_VS_ANERGIC_TH1_DN","description":"Genes down-regulated in comparison of anergy induced CD4 [GeneID=920] T cells versus conventional CD4 [GeneID=920] T cells."} {"geneset":"GSE6269_HEALTHY_VS_FLU_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_HEALTHY_VS_FLU_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute influenza infection."} {"geneset":"GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute influenza infection."} {"geneset":"GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute E. coli infection."} {"geneset":"GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute E. coli infection."} {"geneset":"GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute S. aureus infection."} {"geneset":"GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute S. aureus infection."} {"geneset":"GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute S. pneumoniae infection."} {"geneset":"GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute S. pneumoniae infection."} {"geneset":"GSE6269_FLU_VS_E_COLI_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_FLU_VS_E_COLI_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute E. coli infection."} {"geneset":"GSE6269_FLU_VS_E_COLI_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_FLU_VS_E_COLI_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute E. coli infection."} {"geneset":"GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute S. aureus infection."} {"geneset":"GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute S. aureus infection."} {"geneset":"GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute S. pneumoniae infection."} {"geneset":"GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute S. pneumoniae infection."} {"geneset":"GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute E. coli infection versus PBMC from patients with acute S. aureus infection."} {"geneset":"GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute E. coli infection versus PBMC from patients with acute S. aureus infection."} {"geneset":"GSE6269_E_COLI_VS_STREP_PNEUMO_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_E_COLI_VS_STREP_PNEUMO_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute E. coli infection versus PBMC from patients with acute S. pneumoniae infection."} {"geneset":"GSE6269_E_COLI_VS_STREP_PNEUMO_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_E_COLI_VS_STREP_PNEUMO_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute E. coli infection versus PBMC from patients with acute S. pneumoniae infection."} {"geneset":"GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute infection: S. aureus versus S. pneumoniae."} {"geneset":"GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute infection: S. aureus versus S. pneumoniae."} {"geneset":"GSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] cells stimulated with strong dendritic cells (DC) versus CD4 [GeneID=920] T cells stimulated with weak DCs."} {"geneset":"GSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] cells stimulated with strong dendritic cells (DC) versus CD4 [GeneID=920] T cells stimulated with weak DCs."} {"geneset":"GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP","description":"Genes up-regulated in comparison of untreated peripheral blood mononuclear cells (PBMC) versus PBMCs treated with CSF3 [GeneID=1440]."} {"geneset":"GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_DN","description":"Genes down-regulated in comparison of untreated peripheral blood mononuclear cells (PBMC) versus PBMCs treated with CSF3 [GeneID=1440]."} {"geneset":"GSE7460_TCONV_VS_TREG_LN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_TCONV_VS_TREG_LN_UP","description":"Genes up-regulated in comparison of TconvLN versus TregLN (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_TCONV_VS_TREG_LN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_TCONV_VS_TREG_LN_DN","description":"Genes down-regulated in comparison of TconvLN versus TregLN (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_TCONV_VS_TREG_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_TCONV_VS_TREG_THYMUS_UP","description":"Genes up-regulated in comparison of TconvThy versus TregThy (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_TCONV_VS_TREG_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_TCONV_VS_TREG_THYMUS_DN","description":"Genes down-regulated in comparison of TconvThy versus TregThy (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_UP","description":"Genes up-regulated in comparsion of ActCD8 versus ActCD8TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN","description":"Genes down-regulated in comparsion of ActCD8 versus ActCD8TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP","description":"Genes up-regulated in comparsion of ActTreg versus ActTregTGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN","description":"Genes down-regulated in comparsion of ActTreg versus ActTregTGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CD8_TCELL_VS_TREG_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CD8_TCELL_VS_TREG_ACT_UP","description":"Genes up-regulated in comparsion of ActCD8 versus ActTreg (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CD8_TCELL_VS_TREG_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CD8_TCELL_VS_TREG_ACT_DN","description":"Genes down-regulated in comparsion of ActCD8 versus ActTreg(see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_UP","description":"Genes up-regulated in comparsion of ActCD8 versus ActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN","description":"Genes down-regulated in comparsion of ActCD8 versus ActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_TREG_VS_TCONV_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_TREG_VS_TCONV_ACT_UP","description":"Genes up-regulated in comparsion of ActTreg versus ActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_TREG_VS_TCONV_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_TREG_VS_TCONV_ACT_DN","description":"Genes down-regulated in comparsion of ActTreg versus ActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP","description":"Genes up-regulated in comparsion of ActTregTGF versus ActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_DN","description":"Genes down-regulated in comparsion of ActTregTGF versus ActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP","description":"Genes up-regulated in comparsion of ActCD4 versus ActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN","description":"Genes down-regulated in comparsion of ActCD4 versus ActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP","description":"Genes up-regulated in comparsion of WTActCD4 versus WTActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_DN","description":"Genes down-regulated in comparsion of WTActCD4 versus WTActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_UP","description":"Genes up-regulated in comparsion of sfActCD4 versus sfActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN","description":"Genes down-regulated in comparsion of sfActCD4 versus sfActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP","description":"Genes up-regulated in comparsion of sfActCD4 versus ActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN","description":"Genes down-regulated in comparsion of sfActCD4 versus ActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP","description":"Genes up-regulated in comparsion of sfActCD4TGF versus ActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN","description":"Genes down-regulated in comparsion of sfActCD4TGF versus ActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP","description":"Genes up-regulated in comparsion of sfActCD4 versus WTActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_DN","description":"Genes down-regulated in comparsion of sfActCD4 versus WTActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_UP","description":"Genes up-regulated in comparison of ActCD4 versus WTActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN","description":"Genes down-regulated in comparison of ActCD4 versus WTActCD4 (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP","description":"Genes up-regulated in comparison of ActCD4TGF versus WTActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_DN","description":"Genes down-regulated in comparison of ActCD4TGF versus WTActCD4TGF (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_UP","description":"Genes up-regulated in comparison of Ctrlrv versus Foxp3rv (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_DN","description":"Genes down-regulated in comparison of Ctrlrv versus Foxp3rv (see Fig. 1 in the paper for details)."} {"geneset":"GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_1_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_1_UP","description":"Genes up-regulated in comparison of CTRLrv versus FOXP3rv (see Fig. 1 for details)."} {"geneset":"GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_1_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_1_DN","description":"Genes down-regulated in comparison of CTRLrv versus FOXP3rv (see Fig. 1 for details)."} {"geneset":"GSE7764_NKCELL_VS_SPLENOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7764_NKCELL_VS_SPLENOCYTE_UP","description":"Genes up-regulated in comparison of NK cells versus total splenocytes."} {"geneset":"GSE7764_NKCELL_VS_SPLENOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7764_NKCELL_VS_SPLENOCYTE_DN","description":"Genes down-regulated in comparison of NK cells versus total splenocytes."} {"geneset":"GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP","description":"Genes up-regulated in comparison of NK cells treated with IL15 [GeneID=3567] versus untreated NK cells."} {"geneset":"GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN","description":"Genes down-regulated in comparison of NK cells treated with IL15 [GeneID=3567] versus untreated NK cells."} {"geneset":"GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_UP","description":"Genes up-regulated in comparison of NK cells treated with IL15 [GeneID=3567] versus total splenocytes."} {"geneset":"GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN","description":"Genes down-regulated in comparison of NK cells treated with IL15 [GeneID=3567] versus total splenocytes."} {"geneset":"GSE7852_TREG_VS_TCONV_LN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_TREG_VS_TCONV_LN_UP","description":"Genes up-regulated in comparison of lymph node regulatory T cells versus lymph node conventional T cells."} {"geneset":"GSE7852_TREG_VS_TCONV_LN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_TREG_VS_TCONV_LN_DN","description":"Genes down-regulated in comparison of lymph node regulatory T cells versus lymph node conventional T cells."} {"geneset":"GSE7852_TREG_VS_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_TREG_VS_TCONV_THYMUS_UP","description":"Genes up-regulated in comparison of thymus regulatory T cells versus thymus conventional T cells."} {"geneset":"GSE7852_TREG_VS_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_TREG_VS_TCONV_THYMUS_DN","description":"Genes down-regulated in comparison of thymus regulatory T cells versus thymus conventional T cells."} {"geneset":"GSE7852_TREG_VS_TCONV_FAT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_TREG_VS_TCONV_FAT_UP","description":"Genes up-regulated in comparison of fat tissue regulatory T cells versus fat tissue conventional T cells."} {"geneset":"GSE7852_TREG_VS_TCONV_FAT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_TREG_VS_TCONV_FAT_DN","description":"Genes down-regulated in comparison of fat tissue regulatory T cells versus fat tissue conventional T cells."} {"geneset":"GSE7852_LN_VS_THYMUS_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_LN_VS_THYMUS_TREG_UP","description":"Genes up-regulated in comparison of lymph node regulatory T cells versus thymus regulatory T cells."} {"geneset":"GSE7852_LN_VS_THYMUS_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_LN_VS_THYMUS_TREG_DN","description":"Genes down-regulated in comparison of lymph node regulatory T cells versus thymus regulatory T cells."} {"geneset":"GSE7852_LN_VS_FAT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_LN_VS_FAT_TREG_UP","description":"Genes up-regulated in comparison of lymph node regulatory T cells versus fat tissue regulatory T cells."} {"geneset":"GSE7852_LN_VS_FAT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_LN_VS_FAT_TREG_DN","description":"Genes down-regulated in comparison of lymph node regulatory T cells versus fat tissue regulatory T cells."} {"geneset":"GSE7852_THYMUS_VS_FAT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_THYMUS_VS_FAT_TREG_UP","description":"Genes up-regulated in comparison of thymus regulatory T cells versus fat tissue regulatory T cells."} {"geneset":"GSE7852_THYMUS_VS_FAT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_THYMUS_VS_FAT_TREG_DN","description":"Genes down-regulated in comparison of thymus regulatory T cells versus fat tissue regulatory T cells."} {"geneset":"GSE7852_LN_VS_THYMUS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_LN_VS_THYMUS_TCONV_UP","description":"Genes up-regulated in comparison of lymph node conventional T cells versus thymus conventional T cells."} {"geneset":"GSE7852_LN_VS_THYMUS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_LN_VS_THYMUS_TCONV_DN","description":"Genes down-regulated in comparison of lymph node conventional T cells versus thymus conventional T cells."} {"geneset":"GSE7852_LN_VS_FAT_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_LN_VS_FAT_TCONV_UP","description":"Genes up-regulated in comparison of lymph node conventional T cells versus fat tissue conventional T cells."} {"geneset":"GSE7852_LN_VS_FAT_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_LN_VS_FAT_TCONV_DN","description":"Genes down-regulated in comparison of lymph node conventional T cells versus fat tissue conventional T cells."} {"geneset":"GSE7852_THYMUS_VS_FAT_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_THYMUS_VS_FAT_TCONV_UP","description":"Genes up-regulated in comparison of thymus conventional T cells versus fat tissue conventional T cells."} {"geneset":"GSE7852_THYMUS_VS_FAT_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_THYMUS_VS_FAT_TCONV_DN","description":"Genes down-regulated in comparison of thymus conventional T cells versus fat tissue conventional T cells."} {"geneset":"GSE7852_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_TREG_VS_TCONV_UP","description":"Genes up-regulated in comparison of regulatory T cells versus conventional T cells."} {"geneset":"GSE7852_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7852_TREG_VS_TCONV_DN","description":"Genes down-regulated in comparison of regulatory T cells versus conventional T cells."} {"geneset":"GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP","description":"Genes up-regulated in comparison of control RAW264.7 cells (macrophages) versus those infected with B. abortus."} {"geneset":"GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN","description":"Genes down-regulated in comparison of control RAW264.7 cells (macrophages) versus those infected with B. abortus."} {"geneset":"GSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP","description":"Genes up-regulated in comparison of untreated macrophages versus those treated with IL1."} {"geneset":"GSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN","description":"Genes down-regulated in comparison of untreated macrophages versus those treated with IL1."} {"geneset":"GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP","description":"Genes up-regulated in comparison of untreated macrophages versus those treated with IL6 [GeneID=3569]."} {"geneset":"GSE8515_CTRL_VS_IL6_4H_STIM_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8515_CTRL_VS_IL6_4H_STIM_MAC_DN","description":"Genes down-regulated in comparison of untreated macrophages versus those treated with IL6 [GeneID=3569]."} {"geneset":"GSE8515_IL1_VS_IL6_4H_STIM_MAC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8515_IL1_VS_IL6_4H_STIM_MAC_UP","description":"Genes up-regulated in comparison of untreated macrophages versus those treated with IL1 and IL6 [GeneID=3569]."} {"geneset":"GSE8515_IL1_VS_IL6_4H_STIM_MAC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8515_IL1_VS_IL6_4H_STIM_MAC_DN","description":"Genes down-regulated in comparison of untreated macrophages versus those treated with IL1 and IL6 [GeneID=3569]."} {"geneset":"GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP","description":"Genes up-regulated in IL7R [GeneID=3575] low effector CD8 T cells versus IL7R [GeneID=3575] high effector CD8 T cells."} {"geneset":"GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN","description":"Genes down-regulated in IL7R [GeneID=3575] low effector CD8 T cells versus IL7R [GeneID=3575] high effector CD8 T cells."} {"geneset":"GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_UP","description":"Genes up-regulated in dendritic cells (DC) from spleen versus those from intestine."} {"geneset":"GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN","description":"Genes down-regulated in dendritic cells (DC) from spleen versus those from intestine."} {"geneset":"GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at the time of diagnosis."} {"geneset":"GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at the time of diagnosis."} {"geneset":"GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at 1 month after the diagnosis."} {"geneset":"GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at 1 month after the diagnosis."} {"geneset":"GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at 4 month after the diagnosis."} {"geneset":"GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at 4 month after the diagnosis."} {"geneset":"GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 2 diabetes at the time of diagnosis."} {"geneset":"GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 2 diabetes at the time of diagnosis."} {"geneset":"GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of the diagnosis versus those at 1 month later."} {"geneset":"GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of the diagnosis versus those at 1 month later."} {"geneset":"GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of the diagnosis versus those at 4 months later."} {"geneset":"GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of the diagnosis versus those at 4 months later."} {"geneset":"GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP","description":"Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at 1 month after the diagnosis versus those at 4 months later."} {"geneset":"GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_DN","description":"Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at 1 month after the diagnosis versus those at 4 months later."} {"geneset":"GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP","description":"Genes up-regulated in peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of diagnosis versus those with type 2 diabetes at the time of diagnosis."} {"geneset":"GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN","description":"Genes down-regulated in peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of diagnosis versus those with type 2 diabetes at the time of diagnosis."} {"geneset":"GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP","description":"Genes up-regulated in comparison of untreated macrophages at 4 h versus those treated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_DN","description":"Genes down-regulated in comparison of untreated macrophages at 4 h versus those treated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP","description":"Genes up-regulated in comparison of untreated macrophages at 4 h versus those treated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_DN","description":"Genes down-regulated in comparison of untreated macrophages at 4 h versus those treated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_UP","description":"Genes up-regulated in comparison of untreated macrophages from IRAK4 [GeneID=51135] deficient mice at 4 h versus those treated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN","description":"Genes down-regulated in comparison of untreated macrophages from IRAK4 [GeneID=51135] deficient mice at 4 h versus those treated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP","description":"Genes up-regulated in comparison of untreated macrophages from IRAK4 [GeneID=51135] deficient mice at 4 h versus those treated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_DN","description":"Genes down-regulated in comparison of untreated macrophages from IRAK4 [GeneID=51135] deficient mice at 4 h versus those treated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE9037_WT_VS_IRAK4_KO_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_WT_VS_IRAK4_KO_BMDM_UP","description":"Genes up-regulated in comparison of untreated wild type macrophages at 4 h versus those from IRAK4 [GeneID=51135] deficient mice at 4 h."} {"geneset":"GSE9037_WT_VS_IRAK4_KO_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_WT_VS_IRAK4_KO_BMDM_DN","description":"Genes down-regulated in comparison of untreated wild type macrophages at 4 h versus those from IRAK4 [GeneID=51135] deficient mice at 4 h."} {"geneset":"GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_UP","description":"Genes up-regulated in comparison of untreated wild type macrophages at 1 h versus those from IRAK4 [GeneID=51135] deficient mice treated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_DN","description":"Genes down-regulated in comparison of untreated wild type macrophages at 1 h versus those from IRAK4 [GeneID=51135] deficient mice treated with LPS (TLR4 agonist) at 1 h."} {"geneset":"GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP","description":"Genes up-regulated in comparison of wild type macrophage treated with LPS (TLR4 agonist) at 4 h versus those from IRAK4 [GeneID=51135] deficient mice treated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_DN","description":"Genes down-regulated in comparison of wild type macrophage treated with LPS (TLR4 agonist) at 4 h versus those from IRAK4 [GeneID=51135] deficient mice treated with LPS (TLR4 agonist) at 4 h."} {"geneset":"GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 T cells."} {"geneset":"GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus effector CD8 T cells."} {"geneset":"GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus exhausted CD8 T cells."} {"geneset":"GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus exhausted CD8 T cells."} {"geneset":"GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of naive CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_UP","description":"Genes up-regulated in comparison of effector CD8 T cells versus exhausted CD8 T cells."} {"geneset":"GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN","description":"Genes down-regulated in comparison of effector CD8 T cells versus exhausted CD8 T cells."} {"geneset":"GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of effector CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of effector CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in comparison of exhausted CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in comparison of exhausted CD8 T cells versus memory CD8 T cells."} {"geneset":"GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_UP","description":"Genes up-regulated in comparison of virus specific (gp33) exhausted CD8 T cells versus the virus specific (gp276) cells."} {"geneset":"GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_DN","description":"Genes down-regulated in comparison of virus specific (gp33) exhausted CD8 T cells versus the virus specific (gp276) cells."} {"geneset":"GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with 5000 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with 5000 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with 1 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with 1 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP","description":"Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with control IgG."} {"geneset":"GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN","description":"Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with control IgG."} {"geneset":"GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP","description":"Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus untreated monocytes."} {"geneset":"GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN","description":"Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus untreated monocytes."} {"geneset":"GSE9988_LPS_VS_LOW_LPS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LPS_VS_LOW_LPS_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus those treated with 1 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_LPS_VS_LOW_LPS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LPS_VS_LOW_LPS_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus those treated with 1 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with anti-TREM1 [GeneID=54210]."} {"geneset":"GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with anti-TREM1 [GeneID=54210]."} {"geneset":"GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG."} {"geneset":"GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG."} {"geneset":"GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus untreated monocytes."} {"geneset":"GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus untreated monocytes."} {"geneset":"GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist)."} {"geneset":"GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG."} {"geneset":"GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG."} {"geneset":"GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP","description":"Genes up-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus untreated monocytes."} {"geneset":"GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN","description":"Genes down-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus untreated monocytes."} {"geneset":"GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP","description":"Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG."} {"geneset":"GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_DN","description":"Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG."} {"geneset":"GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP","description":"Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist) versus untreated monocytes."} {"geneset":"GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN","description":"Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist) versus untreated monocytes."} {"geneset":"GSE369_SOCS3_KO_VS_WT_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_SOCS3_KO_VS_WT_LIVER_UP","description":"Genes up-regulated in livers: SOCS3 [GeneID=9021] knockout versus wildtype."} {"geneset":"GSE369_SOCS3_KO_VS_WT_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_SOCS3_KO_VS_WT_LIVER_DN","description":"Genes down-regulated in livers: SOCS3 [GeneID=9021] knockout versus wildtype."} {"geneset":"GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_UP","description":"Genes up-regulated in livers injected with IL6 [GeneID=3569]: SOCS3 [GeneID=9021] knockout versus wildtype."} {"geneset":"GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN","description":"Genes down-regulated in livers injected with IL6 [GeneID=3569]: SOCS3 [GeneID=9021] knockout versus wildtype."} {"geneset":"GSE369_IFNG_KO_VS_WT_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_IFNG_KO_VS_WT_LIVER_UP","description":"Genes up-regulated in liver: IFNG [GeneID=3458] knockout versus wildtype."} {"geneset":"GSE369_IFNG_KO_VS_WT_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_IFNG_KO_VS_WT_LIVER_DN","description":"Genes down-regulated in liver: IFNG [GeneID=3458] knockout versus wildtype."} {"geneset":"GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_UP","description":"Genes up-regulated in liver from SOC3 [GeneID=9021] knockout: untreated versus IL6 [GeneID=3569] injection."} {"geneset":"GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_DN","description":"Genes down-regulated in liver from SOC3 [GeneID=9021] knockout: untreated versus IL6 [GeneID=3569] injection."} {"geneset":"GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_UP","description":"Genes up-regulated in liver from SOCS3 [GeneID=9021] knockout: untreated versus IL6 [GeneID=3569] injection."} {"geneset":"GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN","description":"Genes down-regulated in liver from SOCS3 [GeneID=9021] knockout: untreated versus IL6 [GeneID=3569] injection."} {"geneset":"GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_UP","description":"Genes up-regulated in liver with knockouts of: SOCS3 [GeneID=9021] versus IFNG [GeneID=3458]."} {"geneset":"GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_UP","description":"Genes up-regulated in liver: untreated versus IL6 [GeneID=3569] injection."} {"geneset":"GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN","description":"Genes down-regulated in liver: untreated versus IL6 [GeneID=3569] injection."} {"geneset":"GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_DN","description":"Genes down-regulated in liver with knockouts of: SOCS3 [GeneID=9021] versus IFNG [GeneID=3458]."} {"geneset":"GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_DN","description":"Genes down-regulated in macrophages treated by IL6 [GeneID=3569] for 400min: wildtype versus SOCS3 [GeneID=9021]."} {"geneset":"GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus IL6 [GeneID=3569] for 100min."} {"geneset":"GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus IL6 [GeneID=3569] for 100min."} {"geneset":"GSE411_WT_VS_SOCS3_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_WT_VS_SOCS3_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: wildtype versus SOCS3 [GeneID=9021]."} {"geneset":"GSE411_WT_VS_SOCS3_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_WT_VS_SOCS3_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: wildtype versus SOCS3 [GeneID=9021]."} {"geneset":"GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_UP","description":"Genes up-regulated in macrophages treated by IL6 [GeneID=3569] for 100min: wildtype versus SOCS3 [GeneID=9021]."} {"geneset":"GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_DN","description":"Genes down-regulated in macrophages treated by IL6 [GeneID=3569] for 100min: wildtype versus SOCS3 [GeneID=9021]."} {"geneset":"GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP","description":"Genes up-regulated in macrophages treated by IL6 [GeneID=3569] for 400min: wildtype versus SOCS3 [GeneID=9021]."} {"geneset":"GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with SOCS3 [GeneID=9021] knockout treated by IL6 [GeneID=3569]: 100min versus 400min."} {"geneset":"GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus IL6 [GeneID=3569] for 400min."} {"geneset":"GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages treated by IL6 [GeneID=3569]: 100min versus 400min."} {"geneset":"GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages treated by IL6 [GeneID=3569]: 100min versus 400min."} {"geneset":"GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus IL6 [GeneID=3569] for 400min."} {"geneset":"GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with SOCS3 [GeneID=9021]: untreated versus IL6 [GeneID=3569] for 100min."} {"geneset":"GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with SOCS3 [GeneID=9021]: untreated versus IL6 [GeneID=3569] for 400min."} {"geneset":"GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with SOCS3 [GeneID=9021]: untreated versus IL6 [GeneID=3569] for 400min."} {"geneset":"GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with SOCS3 [GeneID=9021]: untreated versus IL6 [GeneID=3569] for 100min."} {"geneset":"GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with SOCS3 [GeneID=9021] knockout treated by IL6 [GeneID=3569]: 100min versus 400min."} {"geneset":"GSE557_WT_VS_CIITA_KO_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE557_WT_VS_CIITA_KO_DC_UP","description":"Genes up-regulated in dendritic cells: wildtype versus CIITA [GeneID=4261] knockout."} {"geneset":"GSE557_WT_VS_CIITA_KO_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE557_WT_VS_CIITA_KO_DC_DN","description":"Genes down-regulated in dendritic cells: wildtype versus CIITA [GeneID=4261] knockout."} {"geneset":"GSE557_WT_VS_I_AB_KO_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE557_WT_VS_I_AB_KO_DC_UP","description":"Genes up-regulated in dendritic cells: wildtype versus I ab-/- mice."} {"geneset":"GSE557_WT_VS_I_AB_KO_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE557_WT_VS_I_AB_KO_DC_DN","description":"Genes down-regulated in dendritic cells: wildtype versus I ab-/- mice."} {"geneset":"GSE557_CIITA_KO_VS_I_AB_KO_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE557_CIITA_KO_VS_I_AB_KO_DC_UP","description":"Genes up-regulated in dendritic cells: CIITA [GeneID=4261] knockout versus I ab-/- mice."} {"geneset":"GSE557_CIITA_KO_VS_I_AB_KO_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE557_CIITA_KO_VS_I_AB_KO_DC_DN","description":"Genes down-regulated in dendritic cells: CIITA [GeneID=4261] knockout versus I ab-/- mice."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 and IL4 [GeneID=7040;3565] (2h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 and IL4 [GeneID=7040;3565] (2h)."} {"geneset":"GSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 (6h)."} {"geneset":"GSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 (6h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 and IL4 [GeneID=7040;3565] (6h)."} {"geneset":"GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 (2h)."} {"geneset":"GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL4 [GeneID=3565] (6h)."} {"geneset":"GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL4 [GeneID=3565] (48h)."} {"geneset":"GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL4 [GeneID=3565] (48h)."} {"geneset":"GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 (2h)."} {"geneset":"GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus TGFB1 [GeneID=7040] and IL-12 (48h)."} {"geneset":"GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus TGFB1 [GeneID=7040] and IL-12 (48h)."} {"geneset":"GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus IL4 [GeneID=3565] (48h)."} {"geneset":"GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus IL4 [GeneID=3565] (48h)."} {"geneset":"GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus untreated (48h)."} {"geneset":"GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus untreated (48h)."} {"geneset":"GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (48h) versus IL4 [GeneID=3565] (48h)."} {"geneset":"GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL4 [GeneID=3565] (2h)."} {"geneset":"GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL4 [GeneID=3565] (6h)."} {"geneset":"GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (48h) versus untreated (48h)."} {"geneset":"GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL4 [GeneID=3565] (48h) versus untreated (48h)."} {"geneset":"GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL4 [GeneID=3565] (48h) versus untreated (48h)."} {"geneset":"GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL-12 (6h)."} {"geneset":"GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL-12 (48h)."} {"geneset":"GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL-12 (48h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 [GeneID=7040] and IL-12 (2h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 [GeneID=7040] and IL-12 (2h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 [GeneID=7040] and IL-12 (6h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 [GeneID=7040] and IL-12 (6h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 [GeneID=7040] and IL-12 (48h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 [GeneID=7040] and IL-12 (48h)."} {"geneset":"GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL4 [GeneID=3565] (2h)."} {"geneset":"GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus TGFB1 [GeneID=7040] and IL-12 (6h)."} {"geneset":"GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus TGFB1 [GeneID=7040] and IL-12 (6h)."} {"geneset":"GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus IL4 [GeneID=3565] (6h)."} {"geneset":"GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus IL4 [GeneID=3565] (6h)."} {"geneset":"GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus untreated (6h)."} {"geneset":"GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus untreated (6h)."} {"geneset":"GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (6h) versus IL4 [GeneID=3565] (6h)."} {"geneset":"GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (6h) versus IL4 [GeneID=3565] (6h)."} {"geneset":"GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (6h) versus untreated (6h)."} {"geneset":"GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (6h) versus untreated (6h)."} {"geneset":"GSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 (48h)."} {"geneset":"GSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 (48h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus IL-12 (2h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus IL-12 (2h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus TGFB1 [GeneID=7040] and IL-12 (2h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus TGFB1 [GeneID=7040] and IL-12 (2h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus IL4 [GeneID=3565] (2h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus IL4 [GeneID=3565] (2h)."} {"geneset":"GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus untreated (2h)."} {"geneset":"GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus untreated (2h)."} {"geneset":"GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (2h) versus TGFB1 [GeneID=7040] and IL-12 (2h)."} {"geneset":"GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (2h) versus TGFB1 [GeneID=7040] and IL-12 (2h)."} {"geneset":"GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (2h) versus IL4 [GeneID=3565] (2h)."} {"geneset":"GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (2h) versus IL4 [GeneID=3565] (2h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 and IL4 [GeneID=7040;3565] (6h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 and IL4 [GeneID=7040;3565] (48h)."} {"geneset":"GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 and IL4 [GeneID=7040;3565] (48h)."} {"geneset":"GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL-12 (2h)."} {"geneset":"GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL-12 (2h)."} {"geneset":"GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL-12 (6h)."} {"geneset":"GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL4 [GeneID=3565] (2h) versus untreated (2h)."} {"geneset":"GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL4 [GeneID=3565] (2h) versus untreated (2h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus IL-12 (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus IL-12 (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus TGFB1 [GeneID=7050] and IL-12 (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus TGFB1 [GeneID=7050] and IL-12 (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus IL4 [GeneID=3565] (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus IL4 [GeneID=3565] (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus untreated (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus untreated (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (48h) versus IL-12 (48h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (48h) versus TGFB1 [GeneID-7040] and IL-12 (48h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (48h) versus TGFB1 [GeneID-7040] and IL-12 (48h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (48h) versus IL4 [GeneID=3565] (48h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (48h) versus IL4 [GeneID=3565] (48h)."} {"geneset":"GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (48h) versus untreated (48h)."} {"geneset":"GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (48h) versus untreated (48h)."} {"geneset":"GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL4 [GeneID=3565] (6h) versus untreated (6h)."} {"geneset":"GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (48h) versus IL-12 (48h)."} {"geneset":"GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (2h) versus IL4 [GeneID=3565] (2h)."} {"geneset":"GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL4 [GeneID=3565] (6h) versus untreated (6h)."} {"geneset":"GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (2h) versus untreated (2h)."} {"geneset":"GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (2h) versus untreated (2h)."} {"geneset":"GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (2h) versus untreated (2h)."} {"geneset":"GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (2h) versus IL4 [GeneID=3565] (2h)."} {"geneset":"GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (48h) versus IL4 [GeneID=3565] (48h)."} {"geneset":"GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (2h) versus untreated (2h)."} {"geneset":"GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (48h) versus untreated (48h)."} {"geneset":"GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP","description":"Genes up-regulated in mouse embryonic fibroblasts (MEF): untreated versus interferon beta."} {"geneset":"GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_DN","description":"Genes down-regulated in mouse embryonic fibroblasts (MEF): untreated versus interferon beta."} {"geneset":"GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN","description":"Genes down-regulated in CD8 alphabeta HY thymocyte RTOC culture versus CD8 alphaalpha HY thymocyte RTOC culture."} {"geneset":"GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_UP","description":"Genes up-regulated in CD8 alphabeta OT1 thymocyte RTOC culture versus CD8 alphabeta HY thymocyte RTOC culture."} {"geneset":"GSE1112_OT1_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1112_OT1_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_UP","description":"Genes up-regulated in CD8 alphabeta OT1 thymocyte RTOC culture versus CD8 alphaalpha HY thymocyte RTOC culture."} {"geneset":"GSE1112_OT1_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1112_OT1_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN","description":"Genes down-regulated in CD8 alphabeta OT1 thymocyte RTOC culture versus CD8 alphaalpha HY thymocyte RTOC culture."} {"geneset":"GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_UP","description":"Genes up-regulated in CD8 alphabeta HY thymocyte RTOC culture versus CD8 alphaalpha HY thymocyte RTOC culture."} {"geneset":"GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_DN","description":"Genes down-regulated in CD8 alphabeta OT1 thymocyte RTOC culture versus CD8 alphabeta HY thymocyte RTOC culture."} {"geneset":"GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_DN","description":"Genes down-regulated in monocyte-derived macrophages: no priming, stimulated by interferon alpha versus primed by IFNG [GeneID=3458] and then stimulated by interferon alpha."} {"geneset":"GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_UP","description":"Genes up-regulated in monocyte-derived macrophages: untreated versus stimulated by interferon alpha."} {"geneset":"GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_DN","description":"Genes down-regulated in monocyte-derived macrophages: untreated versus stimulated by interferon alpha."} {"geneset":"GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_DN","description":"Genes down-regulated in monocyte-derived macrophages primed by IFNG [GeneID=3458]: untreated versus interferon alpha."} {"geneset":"GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP","description":"Genes up-regulated in monocyte-derived macrophages: no priming versus primed by IFNG [GeneID=3458]."} {"geneset":"GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN","description":"Genes down-regulated in monocyte-derived macrophages: no priming versus primed by IFNG [GeneID=3458]."} {"geneset":"GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_UP","description":"Genes up-regulated in monocyte-derived macrophages: no priming, stimulated by interferon alpha versus primed by IFNG [GeneID=3458] and then stimulated by interferon alpha."} {"geneset":"GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_UP","description":"Genes up-regulated in monocyte-derived macrophages primed by IFNG [GeneID=3458]: untreated versus interferon alpha."} {"geneset":"GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_DN","description":"Genes down-regulated in D10.G4.1 T cell line (3h): control versus treated with NMU [GeneID=10874]."} {"geneset":"GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_DN","description":"Genes down-regulated in D10.G4.1 T cell line (0.8h): control versus treated with NMU [GeneID=10874]."} {"geneset":"GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_UP","description":"Genes up-regulated in D10.G4.1 T cell line (0.8h): control versus treated with NMU [GeneID=10874]."} {"geneset":"GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP","description":"Genes up-regulated in D10.G4.1 T cell line (6h): control versus treated with NMU [GeneID=10874]."} {"geneset":"GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_UP","description":"Genes up-regulated in D10.G4.1 T cell line (3h): control versus treated with NMU [GeneID=10874]."} {"geneset":"GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_UP","description":"Genes up-regulated in D10.G4.1 T cell line (12h): control versus treated with NMU [GeneID=10874]."} {"geneset":"GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_DN","description":"Genes down-regulated in D10.G4.1 T cell line (12h): control versus treated with NMU [GeneID=10874]."} {"geneset":"GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_DN","description":"Genes down-regulated in D10.G4.1 T cell line (6h): control versus treated with NMU [GeneID=10874]."} {"geneset":"GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_DN","description":"Genes down-regulated in NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h versus NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h."} {"geneset":"GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes from: B6 versus NOD mice."} {"geneset":"GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_UP","description":"Genes up-regulated in C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h versus C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h."} {"geneset":"GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_DN","description":"Genes down-regulated in C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h versus NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h."} {"geneset":"GSE2128_C57BL6_VS_NOD_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_C57BL6_VS_NOD_THYMOCYTE_UP","description":"Genes up-regulated in C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h versus NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h."} {"geneset":"GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes from: B6 versus NOD mice."} {"geneset":"GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_DN","description":"Genes down-regulated in C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h versus C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h."} {"geneset":"GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP","description":"Genes up-regulated in NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h versus NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h."} {"geneset":"GSE2128_C57BL6_VS_NOD_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_C57BL6_VS_NOD_THYMOCYTE_DN","description":"Genes down-regulated in C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h versus NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h."} {"geneset":"GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_UP","description":"Genes up-regulated in C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h versus NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h."} {"geneset":"GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_DN","description":"Genes down-regulated in mesenteric lymph nodes: control versus 1 day after injection with soluble form of LTB [GeneID=4050]."} {"geneset":"GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_UP","description":"Genes up-regulated in mesenteric lymph nodes: control versus 1 day after injection with soluble form of LTB [GeneID=4050]."} {"geneset":"GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (9h): S. aureus infection versus control."} {"geneset":"GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (24h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (9h) infection by A. phagocytophilum: heat killed versus live bacteria."} {"geneset":"GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (9h) infection by A. phagocytophilum: heat killed versus live bacteria."} {"geneset":"GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (12h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (9h): treated by heat killed HC60 cell (promyelocytic leukemia) lysate versus A. phagocytophilum infection."} {"geneset":"GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (9h): treated by heat killed HC60 cell (promyelocytic leukemia) lysate versus A. phagocytophilum infection."} {"geneset":"GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (24h): treated by heat killed HC60 cell (promyelocytic leukemia) lysate versus A. phagocytophilum infection."} {"geneset":"GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (24h): treated by heat killed HC60 cell (promyelocytic leukemia) lysate versus A. phagocytophilum infection."} {"geneset":"GSE2405_0H_VS_9H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_9H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (9h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (12h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (24h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (9h): S. aureus infection versus control."} {"geneset":"GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_UP","description":"Genes up-regulated in polymorphonuclear leukocytes 9h after infection by: S. aureus versus A. phagocytophilum."} {"geneset":"GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN","description":"Genes down-regulated in polymorphonuclear leukocytes 9h after infection by: S. aureus versus A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (1.5h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (1.5h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (3h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (3h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (6h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (6h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_0H_VS_9H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_0H_VS_9H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (9h): control versus infection by A. phagocytophilum."} {"geneset":"GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP","description":"Genes up-regulated in polymorphonuclear leukocytes (24h) infection by A. phagocytophilum: heat killed versus live bacteria."} {"geneset":"GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN","description":"Genes down-regulated in polymorphonuclear leukocytes (24h) infection by A. phagocytophilum: heat killed versus live bacteria."} {"geneset":"GSE1566_WT_VS_EZH2_KO_LN_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1566_WT_VS_EZH2_KO_LN_TCELL_UP","description":"Genes up-regulated in lymph node T cells: wildtype versus EZH2 [GeneID=2146] knockout."} {"geneset":"GSE1566_WT_VS_EZH2_KO_LN_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1566_WT_VS_EZH2_KO_LN_TCELL_DN","description":"Genes down-regulated in lymph node T cells: wildtype versus EZH2 [GeneID=2146] knockout."} {"geneset":"GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in thymocytes: double negative versus double positive."} {"geneset":"GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in thymocytes: double positive versus CD4 [GeneID=920] single positive."} {"geneset":"GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_DN","description":"Genes down-regulated in double negative thymocyte versus immature CD4 [GeneID=920] single positive cells."} {"geneset":"GSE22601_DOUBLE_NEGATIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_NEGATIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in thymocytes: double negative versus CD8 single positive."} {"geneset":"GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in immature CD4 [GeneID=920] single positive cells versus double positive thymocytes."} {"geneset":"GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_UP","description":"Genes up-regulated in double negative thymocyte versus immature CD4 [GeneID=920] single positive cells."} {"geneset":"GSE22601_DOUBLE_NEGATIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_NEGATIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in thymocytes: double negative versus CD8 single positive."} {"geneset":"GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in CD4 [GeneID=920] single positive cells: immature versus thymocytes."} {"geneset":"GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in single positive cells: immature CD4 [GeneID=920] versus CD8 thymocytes."} {"geneset":"GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in single positive cells: immature CD4 [GeneID=920] versus CD8 thymocytes."} {"geneset":"GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in thymocytes: double negative versus CD4 [GeneID=920] single positive."} {"geneset":"GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in thymocytes: double negative versus CD4 [GeneID=920] single positive."} {"geneset":"GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in single positive thymocytes: CD4 [GeneID=920] versus CD8."} {"geneset":"GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in thymocytes: double negative versus double positive."} {"geneset":"GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in immature CD4 [GeneID=920] single positive cells versus double positive thymocytes."} {"geneset":"GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in CD4 [GeneID=920] single positive cells: immature versus thymocytes."} {"geneset":"GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in thymocytes: double positive versus CD8 single positive."} {"geneset":"GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in single positive thymocytes: CD4 [GeneID=920] versus CD8."} {"geneset":"GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in thymocytes: double positive versus CD4 [GeneID=920] single positive."} {"geneset":"GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in thymocytes: double positive versus CD8 single positive."} {"geneset":"GSE8835_CD4_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8835_CD4_VS_CD8_TCELL_UP","description":"Genes up-regulated in T cells: CD4 [GeneID=920] versus CD8."} {"geneset":"GSE8835_CD4_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8835_CD4_VS_CD8_TCELL_DN","description":"Genes down-regulated in T cells: CD4 [GeneID=920] versus CD8."} {"geneset":"GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP","description":"Genes up-regulated in T cells from CLL (chronic lymphocytic leukemia) patients: CD4 [GeneID=920] versus CD8."} {"geneset":"GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN","description":"Genes down-regulated in T cells from CLL (chronic lymphocytic leukemia) patients: CD4 [GeneID=920] versus CD8."} {"geneset":"GSE8835_HEALTHY_VS_CLL_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8835_HEALTHY_VS_CLL_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: healthy versus CLL (chronic lymphocytic leukemia)l."} {"geneset":"GSE8835_HEALTHY_VS_CLL_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8835_HEALTHY_VS_CLL_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: healthy versus CLL (chronic lymphocytic leukemia)l."} {"geneset":"GSE8835_HEALTHY_VS_CLL_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8835_HEALTHY_VS_CLL_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: healthy versus CLL (chronic lymphocytic leukemia)."} {"geneset":"GSE8835_HEALTHY_VS_CLL_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8835_HEALTHY_VS_CLL_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: healthy versus CLL (chronic lymphocytic leukemia)."} {"geneset":"GSE2585_CTEC_VS_THYMIC_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CTEC_VS_THYMIC_MACROPHAGE_DN","description":"Genes down-regulated in cortical thymic epithelial cells (cTEC) versus thymic macrophages."} {"geneset":"GSE2585_CTEC_VS_MTEC_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CTEC_VS_MTEC_THYMUS_UP","description":"Genes up-regulated in thymic epithelial cells: cortical (cTEC) versus medullary (mTEC)."} {"geneset":"GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_UP","description":"Genes up-regulated in medullary thymic epithelial cells (mTEC) with CD80 [GeneID=941] high: AIRE [GeneID=326] knockout versus wildtype."} {"geneset":"GSE2585_CTEC_VS_THYMIC_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CTEC_VS_THYMIC_MACROPHAGE_UP","description":"Genes up-regulated in cortical thymic epithelial cells (cTEC) versus thymic macrophages."} {"geneset":"GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_UP","description":"Genes up-regulated in medullary thymic epithelial cells (mTEC) with AIRE [GeneID=326] knockout: CD80 [GeneID=941] high versus low."} {"geneset":"GSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_DN","description":"Genes down-regulated in medullary thymic epithelial cells (mTEC) with CD80 [GeneID=941] low: AIRE [GeneID=326] knockout versus wildtype."} {"geneset":"GSE2585_CTEC_VS_THYMIC_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CTEC_VS_THYMIC_DC_UP","description":"Genes up-regulated in cortical thymic epithelial cells (cTEC) versus thymic dendritic cells."} {"geneset":"GSE2585_CTEC_VS_THYMIC_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CTEC_VS_THYMIC_DC_DN","description":"Genes down-regulated in cortical thymic epithelial cells (cTEC) versus thymic dendritic cells."} {"geneset":"GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_DN","description":"Genes down-regulated in medullary thymic epithelial cells (mTEC) with CD80 [GeneID=941] high: AIRE [GeneID=326] knockout versus wildtype."} {"geneset":"GSE2585_CTEC_VS_MTEC_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CTEC_VS_MTEC_THYMUS_DN","description":"Genes down-regulated in thymic epithelial cells: cortical (cTEC) versus medullary (mTEC)."} {"geneset":"GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_DN","description":"Genes down-regulated in medullary thymic epithelial cells (mTEC) with AIRE [GeneID=326] knockout: CD80 [GeneID=941] high versus low."} {"geneset":"GSE2585_CD80_HIGH_VS_LOW_MTEC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CD80_HIGH_VS_LOW_MTEC_UP","description":"Genes up-regulated in medullary thymic epithelial cells (mTEC): CD80 [GeneID=941] high versus low."} {"geneset":"GSE2585_THYMIC_DC_VS_THYMIC_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_THYMIC_DC_VS_THYMIC_MACROPHAGE_DN","description":"Genes down-regulated in thymic: dendritic cells versus macrophages."} {"geneset":"GSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_UP","description":"Genes up-regulated in medullary thymic epithelial cells (mTEC) with CD80 [GeneID=941] low: AIRE [GeneID=326] knockout versus wildtype."} {"geneset":"GSE2585_THYMIC_MACROPHAGE_VS_MTEC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_THYMIC_MACROPHAGE_VS_MTEC_UP","description":"Genes up-regulated in thymic macrophages versus medullary thymic epithelial cells (mTEC)."} {"geneset":"GSE2585_THYMIC_MACROPHAGE_VS_MTEC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_THYMIC_MACROPHAGE_VS_MTEC_DN","description":"Genes down-regulated in thymic macrophages versus medullary thymic epithelial cells (mTEC)."} {"geneset":"GSE2585_CD80_HIGH_VS_LOW_MTEC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_CD80_HIGH_VS_LOW_MTEC_DN","description":"Genes down-regulated in medullary thymic epithelial cells (mTEC): CD80 [GeneID=941] high versus low."} {"geneset":"GSE2585_THYMIC_DC_VS_MTEC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_THYMIC_DC_VS_MTEC_DN","description":"Genes down-regulated in thymic dendritic cells versus medullary thymic epithelial cells (mTEC)."} {"geneset":"GSE2585_THYMIC_DC_VS_THYMIC_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_THYMIC_DC_VS_THYMIC_MACROPHAGE_UP","description":"Genes up-regulated in thymic: dendritic cells versus macrophages."} {"geneset":"GSE2585_THYMIC_DC_VS_MTEC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2585_THYMIC_DC_VS_MTEC_UP","description":"Genes up-regulated in thymic dendritic cells versus medullary thymic epithelial cells (mTEC)."} {"geneset":"GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus stimulated by IFNG [GeneID=3458] for 3h."} {"geneset":"GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages stimulated by IFNG [GeneID=3458]: 3h versus 24h."} {"geneset":"GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages stimulated by IFNG [GeneID=3458]: 3h versus 24h."} {"geneset":"GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus stimulated by IFNG [GeneID=3458] for 24h."} {"geneset":"GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus stimulated by IFNG [GeneID=3458] for 24h."} {"geneset":"GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages primed by IFNG [GeneID=3458]: untreated versus stimulated by IFNG [GeneID=3458] for 3h."} {"geneset":"GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP","description":"Genes up-regulated in macrophages stimulated by IFNG [GeneID=3458] for 3h: control versus primed by IFNG [GeneID=3458]."} {"geneset":"GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_DN","description":"Genes down-regulated in macrophages stimulated by IFNG [GeneID=3458] for 3h: control versus primed by IFNG [GeneID=3458]."} {"geneset":"GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages primed by IFNG [GeneID=3458]: untreated versus stimulated by IFNG [GeneID=3458] for 24h."} {"geneset":"GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages primed and then stimulated by IFNG [GeneID=3458]: 3h versus 24h."} {"geneset":"GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages primed and then stimulated by IFNG [GeneID=3458]: 3h versus 24h."} {"geneset":"GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus stimulated by IFNG [GeneID=3458] for 3h."} {"geneset":"GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_UP","description":"Genes up-regulated in control macrophages: untreated versus primed by IFNG [GeneID=3458]."} {"geneset":"GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_UP","description":"Genes up-regulated in macrophages stimulated by IFNG [GeneID=3458] for 24h: control versus primed by IFNG [GeneID=3458]."} {"geneset":"GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_DN","description":"Genes down-regulated in macrophages stimulated by IFNG [GeneID=3458] for 24h: control versus primed by IFNG [GeneID=3458]."} {"geneset":"GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages primed by IFNG [GeneID=3458]: untreated versus stimulated by IFNG [GeneID=3458] for 3h."} {"geneset":"GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN","description":"Genes down-regulated in control macrophages: untreated versus primed by IFNG [GeneID=3458]."} {"geneset":"GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages primed by IFNG [GeneID=3458]: untreated versus stimulated by IFNG [GeneID=3458] for 24h."} {"geneset":"GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: control versus Sendai virus infection."} {"geneset":"GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: control versus Sendai virus infection."} {"geneset":"GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN","description":"Genes down-regulated in spleen from DUSP1 [GeneID=1843] knockout: control versus LPS."} {"geneset":"GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP","description":"Genes up-regulated in spleen from DUSP1 [GeneID=1843] knockout: control versus LPS."} {"geneset":"GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN","description":"Genes down-regulated in untreated spleen: DUSP1 [GeneID=1843] knockout versus wildtype."} {"geneset":"GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_UP","description":"Genes up-regulated in spleen from wildtype mice: control versus LPS."} {"geneset":"GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN","description":"Genes down-regulated in spleen from wildtype mice: control versus LPS."} {"geneset":"GSE3565_DUSP1_VS_WT_SPLENOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3565_DUSP1_VS_WT_SPLENOCYTES_UP","description":"Genes up-regulated in untreated spleen: DUSP1 [GeneID=1843] knockout versus wildtype."} {"geneset":"GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_UP","description":"Genes up-regulated in spleen from mice injected with LPS: DUSP1 [GeneID=1843] knockout versus wildtype."} {"geneset":"GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_DN","description":"Genes down-regulated in spleen from mice injected with LPS: DUSP1 [GeneID=1843] knockout versus wildtype."} {"geneset":"GSE3720_UNSTIM_VS_LPS_STIM_VD2_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_UNSTIM_VS_LPS_STIM_VD2_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in Vd2 gamma delta T cells: untreated versus LPS."} {"geneset":"GSE3720_UNSTIM_VS_LPS_STIM_VD2_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_UNSTIM_VS_LPS_STIM_VD2_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in Vd2 gamma delta T cells: untreated versus LPS."} {"geneset":"GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in Vd2 gamma delta T cells: untreated versus phorbol myristate acetate and ionomycin [PubChem=4792;3733]."} {"geneset":"GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in Vd1 gamma delta T cells: untreated versus LPS."} {"geneset":"GSE3720_UNSTIM_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_UNSTIM_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in Vd1 gamma delta T cells: untreated versus phorbol myristate acetate and ionomycin [PubChem=4792;3733]."} {"geneset":"GSE3720_UNSTIM_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_UNSTIM_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in Vd1 gamma delta T cells: untreated versus phorbol myristate acetate and ionomycin [PubChem=4792;3733]."} {"geneset":"GSE3720_LPS_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_LPS_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in Vd1 gamma delta T cells: LPS versus phorbol myristate acetate and ionomycin [PubChem=4792;3733]."} {"geneset":"GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in Vd2 gamma delta T cells: LPS versus phorbol myristate acetate and ionomycin [PubChem=4792;3733]."} {"geneset":"GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in Vd2 gamma delta T cells: LPS versus phorbol myristate acetate and ionomycin [PubChem=4792;3733]."} {"geneset":"GSE3720_LPS_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_LPS_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in Vd1 gamma delta T cells: LPS versus phorbol myristate acetate and ionomycin [PubChem=4792;3733]."} {"geneset":"GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in Vd2 gamma delta T cells: untreated versus phorbol myristate acetate and ionomycin [PubChem=4792;3733]."} {"geneset":"GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_UP","description":"Genes up-regulated in gamma delta T cells stimulated by LPS: Vd1 versus Vd2."} {"geneset":"GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_DN","description":"Genes down-regulated in gamma delta T cells stimulated by LPS: Vd1 versus Vd2."} {"geneset":"GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_UP","description":"Genes up-regulated in gamma delta T cells stimulated by phorbol myristate acetate and ionomycin [PubChem=4792;3733]: Vd1 versus Vd2."} {"geneset":"GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in Vd1 gamma delta T cells: untreated versus LPS."} {"geneset":"GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in gamma delta T cells: Vd1 versus Vd2."} {"geneset":"GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_DN","description":"Genes down-regulated in gamma delta T cells stimulated by phorbol myristate acetate and ionomycin [PubChem=4792;3733]: Vd1 versus Vd2."} {"geneset":"GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in gamma delta T cells: Vd1 versus Vd2."} {"geneset":"GSE3691_IFN_PRODUCING_KILLER_DC_VS_CONVENTIONAL_DC_SPLEEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3691_IFN_PRODUCING_KILLER_DC_VS_CONVENTIONAL_DC_SPLEEN_UP","description":"Genes up-regulated in dendiritic cells from speen: interferon producing killer cells versus conventional."} {"geneset":"GSE3691_IFN_PRODUCING_KILLER_DC_VS_PLASMACYTOID_DC_SPLEEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3691_IFN_PRODUCING_KILLER_DC_VS_PLASMACYTOID_DC_SPLEEN_DN","description":"Genes down-regulated in dendiritic cells from speen: interferon producing killer cells versus plasmacytoid."} {"geneset":"GSE3691_IFN_PRODUCING_KILLER_DC_VS_CONVENTIONAL_DC_SPLEEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3691_IFN_PRODUCING_KILLER_DC_VS_CONVENTIONAL_DC_SPLEEN_DN","description":"Genes down-regulated in dendiritic cells from speen: interferon producing killer cells versus conventional."} {"geneset":"GSE3691_IFN_PRODUCING_KILLER_DC_VS_PLASMACYTOID_DC_SPLEEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3691_IFN_PRODUCING_KILLER_DC_VS_PLASMACYTOID_DC_SPLEEN_UP","description":"Genes up-regulated in dendiritic cells from speen: interferon producing killer cells versus plasmacytoid."} {"geneset":"GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_DN","description":"Genes down-regulated in dendiritic cells from speen: conventional versus plasmacytoid."} {"geneset":"GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP","description":"Genes up-regulated in dendiritic cells from speen: conventional versus plasmacytoid."} {"geneset":"GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_UP","description":"Genes up-regulated in bone marrow-derived mast cells: wildtype versus ADCYAP1R1 [GeneID=117] knockout."} {"geneset":"GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN","description":"Genes down-regulated in bone marrow-derived mast cells: wildtype versus ADCYAP1R1 [GeneID=117] knockout."} {"geneset":"GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve B lymphocytes versus plasma cells."} {"geneset":"GSE4142_NAIVE_VS_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4142_NAIVE_VS_GC_BCELL_UP","description":"Genes up-regulated in B lymphocytes: naü¾™¦”¼ve versus germinal center."} {"geneset":"GSE4142_NAIVE_VS_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4142_NAIVE_VS_GC_BCELL_DN","description":"Genes down-regulated in B lymphocytes: naü¾™¦”¼ve versus germinal center."} {"geneset":"GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve B lymphocytes versus plasma cells."} {"geneset":"GSE4142_PLASMA_CELL_VS_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4142_PLASMA_CELL_VS_GC_BCELL_DN","description":"Genes down-regulated in plasma cells versus germinal center B lymphocytes."} {"geneset":"GSE4142_NAIVE_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4142_NAIVE_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in B lymphocytes: naü¾™¦”¼ve versus memory."} {"geneset":"GSE4142_NAIVE_VS_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4142_NAIVE_VS_MEMORY_BCELL_DN","description":"Genes down-regulated in B lymphocytes: naü¾™¦”¼ve versus memory."} 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{"geneset":"GSE4142_GC_BCELL_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4142_GC_BCELL_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in B lymphocytes: germinal center versus memory."} {"geneset":"GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_3H_UP","description":"Genes up-regulated in monocytes: untreated versus M. tuberculosis 19 kDa lipopeptide (3h)."} {"geneset":"GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_3H_DN","description":"Genes down-regulated in monocytes: untreated versus M. tuberculosis 19 kDa lipopeptide (3h)."} {"geneset":"GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_UP","description":"Genes up-regulated in monocytes: untreated 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{"geneset":"GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_UP","description":"Genes up-regulated in monocytes: untreated versus M. tuberculosis 19 kDa lipopeptide (24h)."} {"geneset":"GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_DN","description":"Genes down-regulated in monocytes: untreated versus M. tuberculosis 19 kDa lipopeptide (24h)."} {"geneset":"GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_UP","description":"Genes up-regulated in monocytes (3h): untreated versus M. tuberculosis 19 kDa lipopeptide."} {"geneset":"GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_DN","description":"Genes 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{"geneset":"GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_DN","description":"Genes down-regulated in monocytes (12h): untreated versus M. tuberculosis 19 kDa lipopeptide."} {"geneset":"GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP","description":"Genes up-regulated in monocytes (24h): untreated versus M. tuberculosis 19 kDa lipopeptide."} {"geneset":"GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_DN","description":"Genes down-regulated in monocytes (24h): untreated versus M. tuberculosis 19 kDa lipopeptide."} {"geneset":"GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP","description":"Genes up-regulated 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{"geneset":"GSE3039_NKT_CELL_VS_B2_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_NKT_CELL_VS_B2_BCELL_DN","description":"Genes down-regulated in NKT cells versus B2 B lymphocytes."} {"geneset":"GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_UP","description":"Genes up-regulated in CD8A [GeneID=925] T cells versus B2 B lymphocytes."} {"geneset":"GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_DN","description":"Genes down-regulated in CD8A [GeneID=925] T cells versus B2 B lymphocytes."} {"geneset":"GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_UP","description":"Genes up-regulated in CD8A [GeneID=925] T cells versus B1 B lymphocytes."} {"geneset":"GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN","description":"Genes down-regulated in CD8A [GeneID=925] T cells versus B1 B lymphocytes."} {"geneset":"GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP","description":"Genes up-regulated in CD8A CD8B [GeneID=925;926] versus B2 B lymphocytes."} {"geneset":"GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_DN","description":"Genes down-regulated in CD8A CD8B [GeneID=925;926] versus B2 B lymphocytes."} {"geneset":"GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP","description":"Genes up-regulated in CD8A CD8B [GeneID=925;926] versus B1 B lymphocytes."} {"geneset":"GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_DN","description":"Genes down-regulated in CD8A CD8B [GeneID=925;926] versus B1 B lymphocytes."} {"geneset":"GSE3039_B2_VS_B1_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_B2_VS_B1_BCELL_UP","description":"Genes up-regulated in B lymphocytes: B2 versus B1."} {"geneset":"GSE3039_B2_VS_B1_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_B2_VS_B1_BCELL_DN","description":"Genes down-regulated in B lymphocytes: B2 versus B1."} {"geneset":"GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP","description":"Genes up-regulated in T cells: CD4 [GeneID=920] versus CD8A [GeneID=925]."} {"geneset":"GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_DN","description":"Genes down-regulated in T cells: CD4 [GeneID=920] versus CD8A [GeneID=925]."} {"geneset":"GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_UP","description":"Genes up-regulated in T cells: CD4 [GeneID=920] versus CD8A CD8B [GeneID=925;926]."} {"geneset":"GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN","description":"Genes down-regulated in T cells: CD4 [GeneID=920] versus CD8A CD8B [GeneID=925;926]."} {"geneset":"GSE3039_CD4_TCELL_VS_B2_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_CD4_TCELL_VS_B2_BCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells versus B2 B lymphocytes."} {"geneset":"GSE3039_CD4_TCELL_VS_B2_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_CD4_TCELL_VS_B2_BCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells versus B2 B lymphocytes."} {"geneset":"GSE3039_CD4_TCELL_VS_B1_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_CD4_TCELL_VS_B1_BCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells versus B1 B lymphocytes."} {"geneset":"GSE3039_CD4_TCELL_VS_B1_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_CD4_TCELL_VS_B1_BCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells versus B1 B lymphocytes."} {"geneset":"GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_UP","description":"Genes up-regulated in NKT cells versus CD8A [GeneID=925] T cells."} {"geneset":"GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_DN","description":"Genes down-regulated in NKT cells versus CD8A [GeneID=925] T cells."} {"geneset":"GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_DN","description":"Genes down-regulated in T cells: CD8A [GeneID=925] versus CD8A CD8B [GeneID=925;926]."} {"geneset":"GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_UP","description":"Genes up-regulated in T cells: CD8A [GeneID=925] versus CD8A CD8B [GeneID=925;926]."} {"geneset":"GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: untreated versus LPS like antigen from O. planktothrix (3h)."} {"geneset":"GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: untreated versus LPS like antigen from O. planktothrix (3h)."} {"geneset":"GSE4748_CTRL_VS_LPS_STIM_DC_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CTRL_VS_LPS_STIM_DC_3H_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: untreated versus LPS (3h)."} {"geneset":"GSE4748_CTRL_VS_LPS_STIM_DC_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CTRL_VS_LPS_STIM_DC_3H_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: untreated versus LPS (3h)."} {"geneset":"GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: untreated versus LPS and LPS like antigen from O. planktothrix (3h)."} {"geneset":"GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: untreated versus LPS and LPS like antigen from O. planktothrix (3h)."} {"geneset":"GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: untreated versus LPS like antigen from O. planktothrix (1h)."} {"geneset":"GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: untreated versus LPS like antigen from O. planktothrix (1h)."} {"geneset":"GSE4748_CYANOBACTERIUM_LPSLIKE_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CYANOBACTERIUM_LPSLIKE_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: LPS like antigen from O. planktothrix (3h) versus LPS and LPS like antigen from O. planktothrix (3h)."} {"geneset":"GSE4748_CYANOBACTERIUM_LPSLIKE_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4748_CYANOBACTERIUM_LPSLIKE_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN","description":"Genes down-regulated in monocyte-derived 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dendritic cells: control versus treated with LGALS1 [GeneID=3956]."} {"geneset":"GSE4984_UNTREATED_VS_GALECTIN1_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_UNTREATED_VS_GALECTIN1_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: control versus treated with LGALS1 [GeneID=3956]."} {"geneset":"GSE4984_UNTREATED_VS_LPS_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_UNTREATED_VS_LPS_TREATED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: control versus LPS."} {"geneset":"GSE4984_UNTREATED_VS_LPS_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_UNTREATED_VS_LPS_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: control versus LPS."} {"geneset":"GSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: untreated versus vehicle."} {"geneset":"GSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: untreated versus vehicle."} {"geneset":"GSE4984_GALECTIN1_VS_LPS_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_GALECTIN1_VS_LPS_STIM_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: LGALS1 [GeneID=3956] versus LPS."} {"geneset":"GSE4984_GALECTIN1_VS_LPS_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_GALECTIN1_VS_LPS_STIM_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: LGALS1 [GeneID=3956] versus LPS."} {"geneset":"GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: LGALS1 [GeneID=3956] versus vehicle."} {"geneset":"GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: LGALS1 [GeneID=3956] versus vehicle."} {"geneset":"GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: LPS versus vehicle."} {"geneset":"GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: LPS versus vehicle."} {"geneset":"GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP","description":"Genes up-regulated in epithelial cells (6h): untreated versus IFNG [GeneID=3458]."} {"geneset":"GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN","description":"Genes down-regulated in epithelial cells (6h): untreated versus IFNG [GeneID=3458]."} {"geneset":"GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP","description":"Genes up-regulated in epithelial cells (6h): untreated versus interferon alpha."} {"geneset":"GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN","description":"Genes down-regulated in epithelial cells (6h): untreated versus interferon alpha."} {"geneset":"GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP","description":"Genes up-regulated in epithelial cells (6h): untreated versus interferon alpha and IFNG [GeneID=3458]."} {"geneset":"GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN","description":"Genes down-regulated in epithelial cells (6h): untreated versus interferon alpha and IFNG [GeneID=3458]."} {"geneset":"GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP","description":"Genes up-regulated in epithelial cells (24h): untreated versus IFNG [GeneID=3458]."} {"geneset":"GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN","description":"Genes down-regulated in epithelial cells (24h): untreated versus IFNG [GeneID=3458]."} {"geneset":"GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP","description":"Genes up-regulated in epithelial cells (24h): untreated versus interferon alpha."} {"geneset":"GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN","description":"Genes down-regulated in epithelial cells (24h): untreated versus interferon alpha."} {"geneset":"GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP","description":"Genes up-regulated in epithelial cells (24h): untreated versus interferon alpha and IFNG [GeneID=3458]."} {"geneset":"GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN","description":"Genes down-regulated in epithelial cells (24h): untreated versus interferon alpha and IFNG [GeneID=3458]."} {"geneset":"GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP","description":"Genes up-regulated in epithelial cells (6h): IFNG [GeneID=3458] versus IFNG [GeneID=3458] and interferon alpha."} {"geneset":"GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN","description":"Genes down-regulated in epithelial cells (6h): IFNG [GeneID=3458] versus IFNG [GeneID=3458] and interferon alpha."} {"geneset":"GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP","description":"Genes up-regulated in epithelial cells (24h): IFNG [GeneID=3458] versus IFNG [GeneID=3458] and interferon alpha."} {"geneset":"GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN","description":"Genes down-regulated in epithelial cells (24h): IFNG [GeneID=3458] versus IFNG [GeneID=3458] and interferon alpha."} {"geneset":"GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP","description":"Genes up-regulated in epithelial cells (6h): interferon alpha versus interferon alpha and IFNG [GeneID=3458]."} {"geneset":"GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN","description":"Genes down-regulated in epithelial cells (6h): interferon alpha versus interferon alpha and IFNG [GeneID=3458]."} {"geneset":"GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP","description":"Genes up-regulated in epithelial cells (24h): interferon alpha versus interferon alpha and IFNG [GeneID=3458]."} {"geneset":"GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN","description":"Genes down-regulated in epithelial cells (24h): interferon alpha versus interferon alpha and IFNG [GeneID=3458]."} {"geneset":"GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP","description":"Genes up-regulated in epithelial cells (6h): IFNG [GeneID=3458] versus interferon alpha."} {"geneset":"GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN","description":"Genes down-regulated in epithelial cells (6h): IFNG [GeneID=3458] versus interferon alpha."} {"geneset":"GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP","description":"Genes up-regulated in epithelial cells (24h): IFNG [GeneID=3458] versus interferon alpha."} {"geneset":"GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN","description":"Genes down-regulated in epithelial cells (24h): IFNG [GeneID=3458] versus interferon alpha."} {"geneset":"GSE4811_CLASSSICALY_ACTIVATED_VS_TYPE_2_ACTIVATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4811_CLASSSICALY_ACTIVATED_VS_TYPE_2_ACTIVATED_MACROPHAGE_UP","description":"Genes up-regulated in activated macrophages: classically (M1) versus alternative (M2)."} {"geneset":"GSE4811_CLASSSICALY_ACTIVATED_VS_TYPE_2_ACTIVATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4811_CLASSSICALY_ACTIVATED_VS_TYPE_2_ACTIVATED_MACROPHAGE_DN","description":"Genes down-regulated in activated macrophages: classically (M1) versus alternative (M2)."} {"geneset":"GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP","description":"Genes up-regulated in CD8 T cells: control versus over-expressing TERT [GeneID=7015]."} {"geneset":"GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_DN","description":"Genes down-regulated in CD8 T cells: control versus over-expressing TERT [GeneID=7015]."} {"geneset":"GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_UP","description":"Genes up-regulated in CD8 T cells: early passage clone over-expressing TERT [GeneID=7015] versus late passage control."} {"geneset":"GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_DN","description":"Genes down-regulated in CD8 T cells: early passage clone over-expressing TERT [GeneID=7015] versus late passage control."} {"geneset":"GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: untreated versus AM580 [PubChem=2126]."} {"geneset":"GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: untreated versus AM580 [PubChem=2126]."} {"geneset":"GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: untreated versus rosiglitazone and AM580 [PubChem=77999;2126]."} {"geneset":"GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: untreated versus rosiglitazone and AM580 [PubChem=77999;2126]."} {"geneset":"GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: rosiglitazone [PubChem=77999] versus AM580 [PubChem=2126]."} {"geneset":"GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: rosiglitazone [PubChem=77999] versus AM580 [PubChem=2126]."} {"geneset":"GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP","description":"Genes up-regulated in 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{"geneset":"GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: AM580 [PubChem=2126] versus rosiglitazone and AM580 [PubChem=77999;2126]."} {"geneset":"GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP","description":"Genes up-regulated in dendritic cells: bone marrow-derived versus follicular."} {"geneset":"GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_DN","description":"Genes down-regulated in dendritic cells: bone marrow-derived versus follicular."} {"geneset":"GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP","description":"Genes up-regulated in ITGAM+ [GeneID=3684] cells from spleen: healthy versus tumor bearing mice."} {"geneset":"GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_DN","description":"Genes down-regulated in ITGAM+ [GeneID=3684] cells from spleen: healthy versus tumor bearing mice."} {"geneset":"GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_UP","description":"Genes up-regulated in ITGAM+ [GeneID=3684] cells (incubated for 24h in complete medium) from spleen: healthy versus tumor bearing mice."} {"geneset":"GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_DN","description":"Genes down-regulated in ITGAM+ [GeneID=3684] cells (incubated for 24h in complete medium) from spleen: healthy versus tumor bearing mice."} {"geneset":"GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_UP","description":"Genes up-regulated in ITGAM+ [GeneID=3684] cells from spleens of tumor bearing mice: processed immediately versus those incubated for 24h in complete medium."} {"geneset":"GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_DN","description":"Genes down-regulated in ITGAM+ [GeneID=3684] cells from spleens of tumor bearing mice: processed immediately versus those incubated for 24h in complete medium."} {"geneset":"GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_UP","description":"Genes up-regulated in monocytes: untreated versus CSF1 [GeneID=1435]."} {"geneset":"GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN","description":"Genes down-regulated in monocytes: untreated versus CSF1 [GeneID=1435] knockout at day 3."} {"geneset":"GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_UP","description":"Genes up-regulated in unstimulated monocytes versus macrophages incubated with CSF1 [GeneID=435] at day 7."} {"geneset":"GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_DN","description":"Genes down-regulated in unstimulated monocytes versus macrophages incubated with CSF1 [GeneID=435] at day 7."} {"geneset":"GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_UP","description":"Genes up-regulated in monocytes versus classically activated (M1) macrophages."} {"geneset":"GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN","description":"Genes down-regulated in monocytes versus classically activated (M1) macrophages."} {"geneset":"GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP","description":"Genes up-regulated in monocytes versus alternatively activated (M2) macrophages."} {"geneset":"GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_DN","description":"Genes down-regulated in monocytes versus alternatively activated (M2) macrophages."} {"geneset":"GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP","description":"Genes up-regulated upon 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{"geneset":"GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: untreated (0 min) versus LPS (45 min)."} {"geneset":"GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: untreated (0 min) versus LPS (45 min)."} {"geneset":"GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: untreated (0 min) versus LPS (180 min)."} {"geneset":"GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: untreated (0 min) versus LPS (180 min)."} {"geneset":"GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL10 [GeneID=3586] and LPS (45 min)."} {"geneset":"GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL10 [GeneID=3586] and LPS (45 min)."} {"geneset":"GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL10 [GeneID=3586] and LPS (180 min)."} {"geneset":"GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL10 [GeneID=3586] and LPS (180 min)."} {"geneset":"GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL6 [GeneID=3569] and LPS (45 min)."} {"geneset":"GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL6 [GeneID=3569] and LPS (45 min)."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP","description":"Genes up-regulated in bone marrow-derived macrophage (45 min): LPS versus IL10 [GeneID=3586] and LPS."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN","description":"Genes down-regulated in bone marrow-derived macrophage (45 min): LPS versus IL10 [GeneID=3586] and LPS."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP","description":"Genes up-regulated in bone marrow-derived macrophage (45 min): LPS versus IL6 [GeneID=3569] and LPS."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN","description":"Genes down-regulated in bone marrow-derived macrophage (45 min): LPS versus IL6 [GeneID=3569] and LPS."} {"geneset":"GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP","description":"Genes up-regulated in bone marrow-derived macrophages (45 min): IL10 [GeneID=3486] and LPS versus IL6 [GeneID=3469] and LPS."} {"geneset":"GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN","description":"Genes down-regulated in bone marrow-derived macrophages (45 min): IL10 [GeneID=3486] and LPS versus IL6 [GeneID=3469] and LPS."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP","description":"Genes up-regulated in bone marrow-derived macrophage (180 min): LPS versus IL10 [GeneID=3586] and LPS."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN","description":"Genes down-regulated in bone marrow-derived macrophage (180 min): LPS versus IL10 [GeneID=3586] and LPS."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_UP","description":"Genes up-regulated in bone marrow-derived macrophages with IL6 [GeneID=3569] knockout and 45 min of stimulation by: LPS versus IL10 [GeneID=3586] and LPS."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_DN","description":"Genes down-regulated in bone marrow-derived macrophages with IL6 [GeneID=3569] knockout and 45 min of stimulation by: LPS versus IL10 [GeneID=3586] and LPS."} {"geneset":"GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP","description":"Genes up-regulated in bone marrow-derived macrophages with IL6 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up-regulated in endothelial cells: interferon beta versus IFNG [GeneID=3458]."} {"geneset":"GSE3920_IFNB_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3920_IFNB_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN","description":"Genes down-regulated in endothelial cells: interferon beta versus IFNG [GeneID=3458]."} {"geneset":"GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_UP","description":"Genes up-regulated fibroblasts: untreated versus interferon alpha."} {"geneset":"GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_UP","description":"Genes up-regulated in endothelial cells: untreated versus exposed to E. burgdoferi."} {"geneset":"GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_DN","description":"Genes down-regulated in endothelial cells: untreated versus exposed to E. burgdoferi."} {"geneset":"GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_UP","description":"Genes up-regulated in endothelial cells: untreated versus IFNG [GeneID=3458]."} {"geneset":"GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN","description":"Genes down-regulated in endothelial cells: untreated versus IFNG [GeneID=3458]."} {"geneset":"GSE6092_UNSTIM_VS_IFNG_STIM_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_UNSTIM_VS_IFNG_STIM_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP","description":"Genes up-regulated in endothelial cells: untreated versus IFNG [GeneID=3459] and B. burgdoferi."} {"geneset":"GSE6092_UNSTIM_VS_IFNG_STIM_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_UNSTIM_VS_IFNG_STIM_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN","description":"Genes down-regulated in endothelial cells: untreated versus IFNG [GeneID=3459] and B. burgdoferi."} {"geneset":"GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_UP","description":"Genes up-regulated in endothelial cells: B. burgdoferi versus IFNG [GeneID=3459] and B. burgdoferi ."} {"geneset":"GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN","description":"Genes down-regulated in endothelial cells: B. burgdoferi versus IFNG [GeneID=3459] and B. burgdoferi ."} {"geneset":"GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP","description":"Genes up-regulated in endothelial cells: IFNG [GeneID=3459] versus IFNG [GeneID=3459] and B. burgdoferi."} {"geneset":"GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN","description":"Genes down-regulated in endothelial cells: IFNG [GeneID=3459] versus IFNG [GeneID=3459] and B. burgdoferi."} {"geneset":"GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_UP","description":"Genes up-regulated in 33D1+ spleen dendritic cells: Flt3L Melanom injected mice versus healthy controls."} {"geneset":"GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_DN","description":"Genes down-regulated in 33D1+ spleen dendritic cells: Flt3L Melanom injected mice versus healthy controls."} {"geneset":"GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_UP","description":"Genes up-regulated in spleen dendritic cells from Flt3L Melanom injected mice: 33D1+ versus DEC205+ subpopulations."} {"geneset":"GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_DN","description":"Genes down-regulated in spleen dendritic cells from Flt3L Melanom injected mice: 33D1+ versus DEC205+ subpopulations."} {"geneset":"GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_UP","description":"Genes up-regulated in spleen dendritic cells from healthy mice: 33D1+ versus DEC205+ subpopulations."} {"geneset":"GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN","description":"Genes down-regulated in spleen dendritic cells from healthy mice: 33D1+ versus DEC205+ subpopulations."} {"geneset":"GSE6259_BCELL_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_BCELL_VS_CD4_TCELL_UP","description":"Genes up-regulated in B lymphocytes versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_BCELL_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_BCELL_VS_CD4_TCELL_DN","description":"Genes down-regulated in B lymphocytes versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_BCELL_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_BCELL_VS_CD8_TCELL_UP","description":"Genes up-regulated in B lymphocytes versus CD8 T cells."} {"geneset":"GSE6259_BCELL_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_BCELL_VS_CD8_TCELL_DN","description":"Genes down-regulated in B lymphocytes versus CD8 T cells."} {"geneset":"GSE6259_CD4_TCELL_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_CD4_TCELL_VS_CD8_TCELL_UP","description":"Genes up-regulated in T cells: CD4 [GeneID=920] versus CD8."} {"geneset":"GSE6259_CD4_TCELL_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_CD4_TCELL_VS_CD8_TCELL_DN","description":"Genes down-regulated in T cells: CD4 [GeneID=920] versus CD8."} {"geneset":"GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_UP","description":"Genes up-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus B lymphocytes."} {"geneset":"GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN","description":"Genes down-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus B lymphocytes."} {"geneset":"GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP","description":"Genes up-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_DN","description":"Genes down-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_UP","description":"Genes up-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_DN","description":"Genes down-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_33D1_POS_DC_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_DC_VS_BCELL_UP","description":"Genes up-regulated in splenic dendritic cells versus 33D1+ B lymphocytes."} {"geneset":"GSE6259_33D1_POS_DC_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_DC_VS_BCELL_DN","description":"Genes down-regulated in splenic dendritic cells versus 33D1+ B lymphocytes."} {"geneset":"GSE6259_33D1_POS_DC_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_DC_VS_CD4_TCELL_UP","description":"Genes up-regulated in splenic CD 33D1+ dendritic cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN","description":"Genes down-regulated in splenic CD 33D1+ dendritic cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_33D1_POS_DC_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_DC_VS_CD8_TCELL_UP","description":"Genes up-regulated in splenic 33D1+ dendritic cells versus CD8 T cells."} {"geneset":"GSE6259_33D1_POS_DC_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_33D1_POS_DC_VS_CD8_TCELL_DN","description":"Genes down-regulated in splenic 33D1+ dendritic cells versus CD8 T cells."} {"geneset":"GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_UP","description":"Genes up-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus B lymphocytes."} {"geneset":"GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_DN","description":"Genes down-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus B lymphocytes."} {"geneset":"GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_UP","description":"Genes up-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_DN","description":"Genes down-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP","description":"Genes up-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus CD8 T cells."} {"geneset":"GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_DN","description":"Genes down-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus CD8 T cells."} {"geneset":"GSE6259_DEC205_POS_DC_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_DEC205_POS_DC_VS_BCELL_UP","description":"Genes up-regulated in splenic dendritic cells: DEC205+ versus B lymphocytes."} {"geneset":"GSE6259_DEC205_POS_DC_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_DEC205_POS_DC_VS_BCELL_DN","description":"Genes down-regulated in splenic dendritic cells: DEC205+ versus B lymphocytes."} {"geneset":"GSE6259_DEC205_POS_DC_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_DEC205_POS_DC_VS_CD4_TCELL_UP","description":"Genes up-regulated in splenic DEC205+ dendritic cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_DEC205_POS_DC_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_DEC205_POS_DC_VS_CD4_TCELL_DN","description":"Genes down-regulated in splenic DEC205+ dendritic cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE6259_DEC205_POS_DC_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_DEC205_POS_DC_VS_CD8_TCELL_UP","description":"Genes up-regulated in splenic DEC205+ dendritic cells versus CD8 T cells."} {"geneset":"GSE6259_DEC205_POS_DC_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6259_DEC205_POS_DC_VS_CD8_TCELL_DN","description":"Genes down-regulated in splenic DEC205+ dendritic cells versus CD8 T cells."} {"geneset":"GSE6681_DELETED_FOXP3_VS_WT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6681_DELETED_FOXP3_VS_WT_TREG_UP","description":"Genes up-regulated in T reg: FOX3P [GeneID=50943] knockout versus wildtype."} {"geneset":"GSE6681_DELETED_FOXP3_VS_WT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6681_DELETED_FOXP3_VS_WT_TREG_DN","description":"Genes down-regulated in T reg: FOX3P [GeneID=50943] knockout versus wildtype."} {"geneset":"GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_UP","description":"Genes up-regulated in lymph node B lymphocytes with influenza infection: wildtype versus IFNAR1 [GeneID=2454] knockout."} {"geneset":"GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN","description":"Genes down-regulated in lymph node B lymphocytes: influenza infected versus interferon beta stimulation."} {"geneset":"GSE3203_HEALTHY_VS_INFLUENZA_INFECTED_LN_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3203_HEALTHY_VS_INFLUENZA_INFECTED_LN_BCELL_UP","description":"Genes up-regulated in lymph node B lymphocytes: influenza infection versus un-infected."} {"geneset":"GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_DN","description":"Genes down-regulated in lymph node B lymphocytes: untreated versus interferon beta."} {"geneset":"GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_UP","description":"Genes up-regulated in lymph node B lymphocytes: influenza infected versus interferon beta stimulation."} {"geneset":"GSE3203_HEALTHY_VS_INFLUENZA_INFECTED_LN_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3203_HEALTHY_VS_INFLUENZA_INFECTED_LN_BCELL_DN","description":"Genes down-regulated in lymph node B lymphocytes: influenza infection versus un-infected."} {"geneset":"GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_UP","description":"Genes up-regulated in lymph node B lymphocytes: untreated versus interferon beta."} {"geneset":"GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_DN","description":"Genes down-regulated in lymph node B lymphocytes with influenza infection: wildtype versus IFNAR1 [GeneID=2454] knockout."} {"geneset":"GSE6875_TCONV_VS_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6875_TCONV_VS_TREG_UP","description":"Genes up-regulated in T conv versus T reg."} {"geneset":"GSE6875_TCONV_VS_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6875_TCONV_VS_TREG_DN","description":"Genes down-regulated in T conv versus T reg."} {"geneset":"GSE6875_TCONV_VS_FOXP3_KO_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6875_TCONV_VS_FOXP3_KO_TREG_UP","description":"Genes up-regulated in T conv versus T reg FOXP3 [GeneID=50943] knockout."} {"geneset":"GSE6875_TCONV_VS_FOXP3_KO_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6875_TCONV_VS_FOXP3_KO_TREG_DN","description":"Genes down-regulated in T conv versus T reg FOXP3 [GeneID=50943] knockout."} {"geneset":"GSE6875_WT_VS_FOXP3_KO_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6875_WT_VS_FOXP3_KO_TREG_UP","description":"Genes up-regulated in T reg: wildtype versus FOXP3 [GeneID=50943] knockout."} {"geneset":"GSE6875_WT_VS_FOXP3_KO_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6875_WT_VS_FOXP3_KO_TREG_DN","description":"Genes down-regulated in T reg: wildtype versus FOXP3 [GeneID=50943] knockout."} {"geneset":"GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGM_BCELL_UP","description":"Genes up-regulated in B lymphocytes expressing IgM - BCR [GeneID=613]: untreated versus anti-HEL."} {"geneset":"GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGM_BCELL_DN","description":"Genes down-regulated in B lymphocytes expressing IgM - BCR [GeneID=613]: untreated versus anti-HEL."} {"geneset":"GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP","description":"Genes up-regulated in B lymphocytes treated by anti-HEL and expressing BCR [GeneID=613] fusions with: IgM versus IgMG."} {"geneset":"GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_DN","description":"Genes down-regulated in B lymphocytes treated by anti-HEL and expressing BCR [GeneID=613] fusions with: IgM versus IgMG."} {"geneset":"GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_UP","description":"Genes up-regulated in B lymphocytes: expressing IgM BCR [GeneID=613] fusion and untreated versus expressing IgMG BCR [GeneID=613] fusion and treated by anti-HEL."} {"geneset":"GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_DN","description":"Genes down-regulated in B lymphocytes: expressing IgM BCR [GeneID=613] fusion and untreated versus expressing IgMG BCR [GeneID=613] fusion and treated by anti-HEL."} {"geneset":"GSE6090_UNSTIM_VS_DC_SIGN_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6090_UNSTIM_VS_DC_SIGN_STIM_DC_UP","description":"Genes up-regulated in dendritic cells: control versus stimulated with anti-CD209 [GeneID=30835] antibody."} {"geneset":"GSE6090_UNSTIM_VS_DC_SIGN_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE6090_UNSTIM_VS_DC_SIGN_STIM_DC_DN","description":"Genes down-regulated in dendritic cells: control versus stimulated with anti-CD209 [GeneID=30835] antibody."} {"geneset":"GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP","description":"Genes up-regulated in immature dendritic cells: untreated versus interferon alpha."} {"geneset":"GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_DN","description":"Genes down-regulated in immature dendritic cells: untreated versus interferon alpha."} {"geneset":"GSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_UP","description":"Genes up-regulated in dendritic cells: untreated versus anti-FcgRIIB."} {"geneset":"GSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_DN","description":"Genes down-regulated in dendritic cells: untreated versus anti-FcgRIIB."} {"geneset":"GSE7509_UNSTIM_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_UNSTIM_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP","description":"Genes up-regulated in dendritic cells: untreated versus inflammatory cytokine cocktail."} {"geneset":"GSE7509_UNSTIM_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_UNSTIM_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN","description":"Genes down-regulated in dendritic cells: untreated versus inflammatory cytokine cocktail."} {"geneset":"GSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP","description":"Genes up-regulated in dendritic cells: anti-FcgRIIB versus inflammatory cytokine cocktail."} {"geneset":"GSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN","description":"Genes down-regulated in dendritic cells: anti-FcgRIIB versus inflammatory cytokine cocktail."} {"geneset":"GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_UP","description":"Genes up-regulated in monocytes: untreated versus anti- FcgRIIB."} {"geneset":"GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN","description":"Genes down-regulated in monocytes: untreated versus anti- FcgRIIB."} {"geneset":"GSE7509_DC_VS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_DC_VS_MONOCYTE_UP","description":"Genes up-regulated in dendritic cells versus monocytes."} {"geneset":"GSE7509_DC_VS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_DC_VS_MONOCYTE_DN","description":"Genes down-regulated in dendritic cells versus monocytes."} {"geneset":"GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_UP","description":"Genes up-regulated in response to anti-FcgRIIB: dendritic cells versus monocytes."} {"geneset":"GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN","description":"Genes down-regulated in response to anti-FcgRIIB: dendritic cells versus monocytes."} {"geneset":"GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from lymph nodes: naü¾™¦”¼ve versus day 7 after immunization."} {"geneset":"GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from lymph nodes: naü¾™¦”¼ve versus day 7 after immunization."} {"geneset":"GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from lymph nodes: naü¾™¦”¼ve versus day 28 after immunization."} {"geneset":"GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from lymph nodes: naü¾™¦”¼ve versus day 28 after immunization."} {"geneset":"GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from lymph nodes: naü¾™¦”¼ve versus day 28 after immunization."} {"geneset":"GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from lymph nodes: naü¾™¦”¼ve versus day 28 after immunization."} {"geneset":"GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus LPS."} {"geneset":"GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus LPS."} {"geneset":"GSE7348_UNSTIM_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7348_UNSTIM_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: naü¾™¦”¼ve untreated versus tolerant stimulated by LPS."} {"geneset":"GSE7348_UNSTIM_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7348_UNSTIM_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: naü¾™¦”¼ve untreated versus tolerant stimulated by LPS."} {"geneset":"GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages in response to LPS: naü¾™¦”¼ve versus tolerant."} {"geneset":"GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages in response to LPS: naü¾™¦”¼ve versus tolerant."} {"geneset":"GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP","description":"Genes up-regulated in spleens from mice immunized with ova peptides alone versus those immunized with LPS as adjuvant."} {"geneset":"GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN","description":"Genes down-regulated in spleens from mice immunized with ova peptides alone versus those immunized with LPS as adjuvant."} {"geneset":"GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP","description":"Genes up-regulated in spleens: LPS versus monophosphoryl lipid A."} {"geneset":"GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN","description":"Genes down-regulated in spleens: LPS versus monophosphoryl lipid A."} {"geneset":"GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP","description":"Genes up-regulated in spleens from mice immunized with ova peptides alone versus those immunized with monophosphoryl lipid A as adjuvant."} {"geneset":"GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN","description":"Genes down-regulated in spleens from mice immunized with ova peptides alone versus those immunized with monophosphoryl lipid A as adjuvant."} {"geneset":"GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_UP","description":"Genes up-regulated during B lymphocyte differentiation: pre-B I versus small pre-B II."} {"geneset":"GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_DN","description":"Genes down-regulated during B lymphocyte differentiation: pre-B I versus small pre-B II."} {"geneset":"GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_UP","description":"Genes up-regulated during B lymphocyte differentiation: pre-B I versus large pre-B II."} {"geneset":"GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_DN","description":"Genes down-regulated during B lymphocyte differentiation: pre-B I versus large pre-B II."} {"geneset":"GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP","description":"Genes up-regulated during B lymphocyte differentiation: pre-B I versus VPREB1+ [GeneID=7441] large pre-B II."} {"geneset":"GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN","description":"Genes down-regulated during B lymphocyte differentiation: pre-B I versus VPREB1+ [GeneID=7441] large pre-B II."} {"geneset":"GSE4590_SMALL_VS_LARGE_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_SMALL_VS_LARGE_PRE_BCELL_UP","description":"Genes up-regulated during B lymphocyte differentiation: small pre-B II versus large pre-B II."} {"geneset":"GSE4590_SMALL_VS_LARGE_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_SMALL_VS_LARGE_PRE_BCELL_DN","description":"Genes down-regulated during B lymphocyte differentiation: small pre-B II versus large pre-B II."} {"geneset":"GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP","description":"Genes up-regulated during B lymphocyte differentiation: small pre-B II versus VPREB1+ [GeneID=7441] large pre-B II."} {"geneset":"GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_DN","description":"Genes down-regulated during B lymphocyte differentiation: small pre-B II versus VPREB1+ [GeneID=7441] large pre-B II."} {"geneset":"GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP","description":"Genes up-regulated during B lymphocyte differentiation: large pre-B II versus VPREB1+ [GeneID=7441] pre-B Il."} {"geneset":"GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN","description":"Genes down-regulated during B lymphocyte differentiation: large pre-B II versus VPREB1+ [GeneID=7441] pre-B Il."} {"geneset":"GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP","description":"Genes up-regulated in monocytes after HCMV infection: untreated versus BAY 11-7082 [PubChem=5353431]."} {"geneset":"GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN","description":"Genes down-regulated in monocytes after HCMV infection: untreated versus BAY 11-7082 [PubChem=5353431]."} {"geneset":"GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP","description":"Genes up-regulated in monocytes after HCMV infection: untreated versus Ly294002 [PubChem=3973]."} {"geneset":"GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN","description":"Genes down-regulated in monocytes after HCMV infection: untreated versus Ly294002 [PubChem=3973]."} {"geneset":"GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP","description":"Genes up-regulated in monocytes after HCMV infection: BAY 11-7082 [PubChem=5353431] versus Ly294002 [PubChem=3973]."} {"geneset":"GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN","description":"Genes down-regulated in monocytes after HCMV infection: BAY 11-7082 [PubChem=5353431] versus Ly294002 [PubChem=3973]."} {"geneset":"GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells with in vivo expansion: IL6 [GeneID=3569] versus IFNG [GeneID=3458]."} {"geneset":"GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells with in vivo expansion: IL6 [GeneID=3569] versus IFNG [GeneID=3458]."} {"geneset":"GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_UP","description":"Genes up-regulated in FOLR4- CD4 [GeneID=390243;920] T cells treated by phorbol myristate acetate and ionomycin [PubChem=4792;3733] from: BALB/c versus SKG mice."} {"geneset":"GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN","description":"Genes down-regulated in FOLR4- CD4 [GeneID=390243;920] T cells treated by phorbol myristate acetate and ionomycin [PubChem=4792;3733] from: BALB/c versus SKG mice."} {"geneset":"GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_UP","description":"Genes up-regulated in macrophages with IL10 [GeneID=3586] knockout in response to 10 min treatment by: LPS versus LPS and IL10 [GeneID=3586]."} {"geneset":"GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_DN","description":"Genes down-regulated in macrophages with IL10 [GeneID=3586] knockout in response to 10 min treatment by: LPS versus LPS and IL10 [GeneID=3586]."} {"geneset":"GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_UP","description":"Genes up-regulated in macrophages with IL10 [GeneID=3586] knockout in response to 20 min treatment by: LPS versus LPS and IL10 [GeneID=3586]."} {"geneset":"GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_DN","description":"Genes down-regulated in macrophages with IL10 [GeneID=3586] knockout in response to 20 min treatment by: LPS versus LPS and IL10 [GeneID=3586]."} {"geneset":"GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_UP","description":"Genes up-regulated in macrophages with IL10 [GeneID=3586] knockout in response to 30 min treatment by: LPS versus LPS and IL10 [GeneID=3586]."} {"geneset":"GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_DN","description":"Genes down-regulated in macrophages with IL10 [GeneID=3586] knockout in response to 30 min treatment by: LPS versus LPS and IL10 [GeneID=3586]."} {"geneset":"GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with IL10 [GeneID=3586] knockout treated by LPS: 10 min versus 30 min."} {"geneset":"GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with IL10 [GeneID=3586] knockout treated by LPS: 10 min versus 30 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{"geneset":"GSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN","description":"Genes down-regulated in allogeneic T cells after stimulation with dendritic cells from: liver versus spleen."} {"geneset":"GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP","description":"Genes up-regulated in allogeneic T cells after stimulation with dendritic cells from lymph nodes: mesenteric (mLN) versus peripheral (pLN)."} {"geneset":"GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN","description":"Genes down-regulated in allogeneic T cells after stimulation with dendritic cells from lymph nodes: mesenteric (mLN) versus peripheral (pLN)."} {"geneset":"GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP","description":"Genes up-regulated in allogeneic T cells after stimulation with dendritic cells from: mesenteric lymph nodes (mLN) versus spleen."} {"geneset":"GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN","description":"Genes down-regulated in allogeneic T cells after stimulation with dendritic cells from: mesenteric lymph nodes (mLN) versus spleen."} {"geneset":"GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP","description":"Genes up-regulated in allogeneic T cells after stimulation with dendritic cells from: peripheral lymph nodes (mLN) versus spleen."} {"geneset":"GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN","description":"Genes down-regulated in allogeneic T cells after stimulation with dendritic cells from: peripheral lymph nodes (mLN) versus spleen."} {"geneset":"GSE10240_CTRL_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_CTRL_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","description":"Genes down-regulated in primary bronchial epithelial cells: control versus stimulated with IL17A [GeneID=3605]."} {"geneset":"GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","description":"Genes up-regulated in primary bronchial epithelial cells stimulated with: IL22 [GeneID=50616] versus IL17A [GeneID=3605]."} {"geneset":"GSE10240_CTRL_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_CTRL_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","description":"Genes up-regulated in primary bronchial epithelial cells: control versus stimulated with IL17A [GeneID=3605]."} {"geneset":"GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","description":"Genes down-regulated in primary bronchial epithelial cells: control versus stimulated with IL22 [GeneID=50616]."} {"geneset":"GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","description":"Genes up-regulated in primary bronchial epithelial cells: control versus stimulated with IL22 [GeneID=50616]."} {"geneset":"GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","description":"Genes up-regulated in primary bronchial epithelial cells: control versus stimulated with IL17A and IL22 [GeneID=3605;50616]."} {"geneset":"GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","description":"Genes down-regulated in primary bronchial epithelial cells: control versus stimulated with IL17A and IL22 [GeneID=3605;50616]."} {"geneset":"GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","description":"Genes up-regulated in primary bronchial epithelial cells stimulated with: IL22 [GeneID=50616] versus IL17A and IL22 [GeneID=3605;50616]."} {"geneset":"GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","description":"Genes down-regulated in primary bronchial epithelial cells stimulated with: IL22 [GeneID=50616] versus IL17A and IL22 [GeneID=3605;50616]."} {"geneset":"GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","description":"Genes down-regulated in primary bronchial epithelial cells stimulated with: IL22 [GeneID=50616] versus IL17A [GeneID=3605]."} {"geneset":"GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN","description":"Genes down-regulated in primary bronchial epithelial cells stimulated with: IL17A [GeneID=50616] versus IL17A and IL22 [GeneID=3605;50616]."} {"geneset":"GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP","description":"Genes up-regulated in primary bronchial epithelial cells stimulated with: IL17A [GeneID=50616] versus IL17A and IL22 [GeneID=3605;50616]."} {"geneset":"GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_UP","description":"Genes up-regulated in IRF4 and IRF8 [GeneID=3662;3394] null pre-B cells treated with 0.25 ng/ml IL7 [GeneID=3574] versus the cells treated with 5 ng/ml IL7 [GeneID=3574] and transduced with IRF4 [GeneID=3662]."} {"geneset":"GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_DN","description":"Genes down-regulated in IRF4 and IRF8 [GeneID=3662;3394] null pre-B cells treated with IL7 [GeneID=3574]: 5 ng/ml versus 0.25ng/ml."} {"geneset":"GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN","description":"Genes down-regulated in IRF4 and IRF8 [GeneID=3662;3394] null pre-B cell treated with 5ng/ml IL7 [GeneID=3574] versus those transduced with IRF4 [GeneID=3662]."} {"geneset":"GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP","description":"Genes up-regulated in IRF4 and IRF8 [GeneID=3662;3394] null pre-B cells treated with IL7 [GeneID=3574]: 5 ng/ml versus 0.25ng/ml."} {"geneset":"GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_UP","description":"Genes up-regulated in IRF4 and IRF8 [GeneID=3662;3394] null pre-B cell treated with 5ng/ml IL7 [GeneID=3574] versus those transduced with IRF4 [GeneID=3662]."} {"geneset":"GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN","description":"Genes down-regulated in IRF4 and IRF8 [GeneID=3662;3394] null pre-B cells treated with 0.25 ng/ml IL7 [GeneID=3574] versus the cells treated with 5 ng/ml IL7 [GeneID=3574] and transduced with IRF4 [GeneID=3662]."} {"geneset":"GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_UP","description":"Genes up-regulated in Sez-2 cells (T cell lymphoma): untreated versus IL2 [GeneID=3558]."} {"geneset":"GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN","description":"Genes down-regulated in Sez-2 cells (T cell lymphoma): untreated versus IL2 [GeneID=3558]."} {"geneset":"GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP","description":"Genes up-regulated in Sez-2 cells (T cell lymphoma): untreated versus IL5 [GeneID=3567]."} {"geneset":"GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN","description":"Genes down-regulated in Sez-2 cells (T cell lymphoma): untreated versus IL5 [GeneID=3567]."} {"geneset":"GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP","description":"Genes up-regulated in Sez-2 cells (T cell lymphoma): untreated versus IL21 [GeneID=59067]."} {"geneset":"GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN","description":"Genes down-regulated in Sez-2 cells (T cell lymphoma): untreated versus IL21 [GeneID=59067]."} {"geneset":"GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP","description":"Genes up-regulated in Sez-2 cells (T cell lymphoma): untreated versus IL15 [GeneID=3600]."} {"geneset":"GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN","description":"Genes down-regulated in Sez-2 cells (T cell lymphoma): untreated versus IL15 [GeneID=3600]."} {"geneset":"GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP","description":"Genes up-regulated in Sez-2 cells (T cell lymphoma): IL2 [GeneID=3558] versus IL21 [GeneID=59067]."} {"geneset":"GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN","description":"Genes down-regulated in Sez-2 cells (T cell lymphoma): IL2 [GeneID=3558] versus IL21 [GeneID=59067]."} {"geneset":"GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP","description":"Genes up-regulated in Sez-2 cells (T cell lymphoma): IL15 [GeneID=3600] versus IL21 [GeneID=3600]."} {"geneset":"GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN","description":"Genes down-regulated in Sez-2 cells (T cell lymphoma): IL15 [GeneID=3600] versus IL21 [GeneID=3600]."} {"geneset":"GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_UP","description":"Genes up-regulated in T conv in response to TGF-beta: expressing constantly active form of AKT1 [GeneID=207] versus control."} {"geneset":"GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_DN","description":"Genes down-regulated in T conv in response to TGF-beta: expressing constantly active form of AKT1 [GeneID=207] versus control."} {"geneset":"GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_DN","description":"Genes down-regulated in tracheal epithelial cells infected with UV inactivated versus intact Sendai virus."} {"geneset":"GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_UP","description":"Genes up-regulated in tracheal epithelial cells infected with UV inactivated versus intact Sendai virus."} {"geneset":"GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP","description":"Genes up-regulated in plasmacytoid dendritic cells: IL3 [GeneID=3562] versus IL3 [GeneID=3562] and the HIV matrix protein p17."} {"geneset":"GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_DN","description":"Genes down-regulated in plasmacytoid dendritic cells: IL3 [GeneID=3562] versus IL3 [GeneID=3562] and the HIV matrix protein p17."} {"geneset":"GSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_UP","description":"Genes up-regulated in plasmacytoid dendritic cells: IL3 [GeneID=3562] versus IL3 [GeneID=3562] and CpG."} {"geneset":"GSE10147_IL3_AND_HIVP17_VS_IL3_AND_CPG_STIM_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10147_IL3_AND_HIVP17_VS_IL3_AND_CPG_STIM_PDC_DN","description":"Genes down-regulated in plasmacytoid dendritic cells treated with IL3 [GeneID=3562]: HIV matrix protein p17 versus CpG."} {"geneset":"GSE10147_IL3_AND_HIVP17_VS_IL3_AND_CPG_STIM_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10147_IL3_AND_HIVP17_VS_IL3_AND_CPG_STIM_PDC_UP","description":"Genes up-regulated in plasmacytoid dendritic cells treated with IL3 [GeneID=3562]: HIV matrix protein p17 versus CpG."} {"geneset":"GSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_DN","description":"Genes down-regulated in plasmacytoid dendritic cells: IL3 [GeneID=3562] versus IL3 [GeneID=3562] and CpG."} {"geneset":"GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_DN","description":"Genes down-regulated in wildtype B cells versus BAFF-transgenic (over-express TNFSF13B [GeneID=10673]) B cells from lymph node."} {"geneset":"GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP","description":"Genes up-regulated in wildtype B cells versus BAFF-transgenic (over-express TNFSF13B [GeneID=10673]) B cells from lymph node."} {"geneset":"GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_UP","description":"Genes up-regulated in macrophages from patients with synovial fluid rheumatoid arthritis versus monocyte-derived macrophages from healthy persons."} {"geneset":"GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN","description":"Genes down-regulated in macrophages from patients with synovial fluid rheumatoid arthritis versus monocyte-derived macrophages from healthy persons."} {"geneset":"GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP","description":"Genes up-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 3h."} {"geneset":"GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN","description":"Genes down-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 3h."} {"geneset":"GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP","description":"Genes up-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h."} {"geneset":"GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN","description":"Genes down-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h."} {"geneset":"GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP","description":"Genes up-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h."} {"geneset":"GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_DN","description":"Genes down-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h."} {"geneset":"GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages differentiated for 5 days in the presence of: IL4 [GeneID=3565] versus IL4 [GeneID=3565] and dexamethasone [PubChem=5743]."} {"geneset":"GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages differentiated for 5 days in the presence of: IL4 [GeneID=3565] versus IL4 [GeneID=3565] and dexamethasone [PubChem=5743]."} {"geneset":"GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: 5 days with IL4 [GeneID=3565] and dexamethasone [PubChem=5743] followed by TGFB1 [GeneID=7040] for 24h versus 5 days with IL4 [GeneID=3565] followed by TGFB1 [GeneID=7040] for 24h."} {"geneset":"GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: 5 days with IL4 [GeneID=3565] and dexamethasone [PubChem=5743] followed by TGFB1 [GeneID=7040] for 24h versus 5 days with IL4 [GeneID=3565] followed by TGFB1 [GeneID=7040] for 24h."} {"geneset":"GSE11386_NAIVE_VS_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11386_NAIVE_VS_MEMORY_BCELL_DN","description":"Genes down-regulated in B lymphocytes: naü¾™¦”¼ve versus memory."} {"geneset":"GSE11386_NAIVE_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11386_NAIVE_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in B lymphocytes: naü¾™¦”¼ve versus memory."} {"geneset":"GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP","description":"Genes up-regulated in dendritic cells: wildtype versus NFKB2 [GeneID=4791]."} {"geneset":"GSE7219_WT_VS_NIK_NFKB2_KO_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7219_WT_VS_NIK_NFKB2_KO_DC_DN","description":"Genes down-regulated in dendritic cells: wildtype versus NFKB2 [GeneID=4791]."} {"geneset":"GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP","description":"Genes up-regulated in dendric cells: untreated versus LPS and anti-CD40."} {"geneset":"GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_DN","description":"Genes down-regulated in dendric cells: untreated versus LPS and anti-CD40."} {"geneset":"GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP","description":"Genes up-regulated in dendritic cell NIK NFkB2-KO versus dendritic cell NIK NFkB2-KO LPS and anti-CD40 stimulated."} {"geneset":"GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN","description":"Genes down-regulated in dendritic cell NIK NFkB2-KO versus dendritic cell NIK NFkB2-KO LPS and anti-CD40 stimulated."} {"geneset":"GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_UP","description":"Genes up-regulated in dendritic cell wildtype LPS and anti-CD40 stimulated versus dendritic cell NIK NFkB2-KO LPS and anti-CD40 stimulated."} {"geneset":"GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_DN","description":"Genes down-regulated in dendritic cell wildtype LPS and anti-CD40 stimulated versus dendritic cell NIK NFkB2-KO LPS and anti-CD40 stimulated."} {"geneset":"GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP","description":"Genes up-regulated in 4 day cultures of bone marrow progenitors: wildtype versus MIR223 [GeneID=407008] knockout."} {"geneset":"GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_UP","description":"Genes up-regulated in neutrophils from MIR223 [GeneID=407008] bone marrow versus the wildtype cells."} {"geneset":"GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_DN","description":"Genes down-regulated in 4 day cultures of bone marrow progenitors: wildtype versus MIR223 [GeneID=407008] knockout."} {"geneset":"GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_DN","description":"Genes down-regulated in neutrophils: MIR223 [GeneID=407008] knockout versus wildtype."} {"geneset":"GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_DN","description":"Genes down-regulated in 8 day cultures of bone marrow progenitors: wildtype versus MIR223 [GeneID=407008] knockout."} {"geneset":"GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_DN","description":"Genes down-regulated in neutrophils from MIR223 [GeneID=407008] bone marrow versus the wildtype cells."} {"geneset":"GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_UP","description":"Genes up-regulated in 8 day cultures of bone marrow progenitors: wildtype versus MIR223 [GeneID=407008] knockout."} {"geneset":"GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_UP","description":"Genes up-regulated in neutrophils: MIR223 [GeneID=407008] knockout versus wildtype."} {"geneset":"GSE12003_4D_VS_8D_CULTURE_BM_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12003_4D_VS_8D_CULTURE_BM_PROGENITOR_UP","description":"Genes up-regulated in of bone marrow progenitors: 4- versus 8-day cultures."} {"geneset":"GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_DN","description":"Genes down-regulated in of bone marrow progenitors with MIR223 [GeneID=407008] knockout: 4- versus 8-day cultures."} {"geneset":"GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_UP","description":"Genes up-regulated in of bone marrow progenitors with MIR223 [GeneID=407008] knockout: 4- versus 8-day cultures."} {"geneset":"GSE12003_4D_VS_8D_CULTURE_BM_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12003_4D_VS_8D_CULTURE_BM_PROGENITOR_DN","description":"Genes down-regulated in of bone marrow progenitors: 4- versus 8-day cultures."} {"geneset":"GSE11884_WT_VS_FURIN_KO_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11884_WT_VS_FURIN_KO_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve wildtype CD4 [GeneID=920] T cells versus those from T cell specific FURIN [GeneID=5045] knockout mice."} {"geneset":"GSE11884_WT_VS_FURIN_KO_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11884_WT_VS_FURIN_KO_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve wildtype CD4 [GeneID=920] T cells versus those from T cell specific FURIN [GeneID=5045] knockout mice."} {"geneset":"GSE11818_WT_VS_DICER_KO_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11818_WT_VS_DICER_KO_TREG_DN","description":"Genes down-regulated in T reg: wildtype versus DICER1 [GeneID=23405] knockout."} {"geneset":"GSE11818_WT_VS_DICER_KO_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11818_WT_VS_DICER_KO_TREG_UP","description":"Genes up-regulated in T reg: wildtype versus DICER1 [GeneID=23405] knockout."} {"geneset":"GSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_UP","description":"Genes up-regulated in dendritic cells: immature versus mature stimulatory."} {"geneset":"GSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_DN","description":"Genes down-regulated in dendritic cells: immature versus mature stimulatory."} {"geneset":"GSE9946_IMMATURE_VS_LISTERIA_INF_MATURE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_IMMATURE_VS_LISTERIA_INF_MATURE_DC_UP","description":"Genes up-regulated in dendritic cells: immature versus mature inhibitory infected with L. monocytogenes."} {"geneset":"GSE9946_IMMATURE_VS_LISTERIA_INF_MATURE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_IMMATURE_VS_LISTERIA_INF_MATURE_DC_DN","description":"Genes down-regulated in dendritic cells: immature versus mature inhibitory infected with L. monocytogenes."} {"geneset":"GSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP","description":"Genes up-regulated in dendritic cells: immature versus mature inhibitory treated by prostaglandin E2 [PubChem=5280360]."} {"geneset":"GSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN","description":"Genes down-regulated in dendritic cells: immature versus mature inhibitory treated by prostaglandin E2 [PubChem=5280360]."} {"geneset":"GSE9946_MATURE_STIMULATORY_VS_LISTERIA_INF_MATURE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_MATURE_STIMULATORY_VS_LISTERIA_INF_MATURE_DC_UP","description":"Genes up-regulated in mature dendritic cells: stimulatory versus inhibitory infected with L. monocytogenes."} {"geneset":"GSE9946_MATURE_STIMULATORY_VS_LISTERIA_INF_MATURE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_MATURE_STIMULATORY_VS_LISTERIA_INF_MATURE_DC_DN","description":"Genes down-regulated in mature dendritic cells: stimulatory versus inhibitory infected with L. monocytogenes."} {"geneset":"GSE9946_MATURE_STIMULATORY_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_MATURE_STIMULATORY_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP","description":"Genes up-regulated in mature dendritic cells: stimulatory versus inhibitory treated by prostaglandin E2 [PubChem=5280360]."} {"geneset":"GSE9946_MATURE_STIMULATORY_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_MATURE_STIMULATORY_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN","description":"Genes down-regulated in mature dendritic cells: stimulatory versus inhibitory treated by prostaglandin E2 [PubChem=5280360]."} {"geneset":"GSE9946_LISTERIA_INF_MATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_LISTERIA_INF_MATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP","description":"Genes up-regulated in mature inhibitory dendritic cells: L. monocytogenes infection versus prostaglandin E2 [PubChem=5280360]."} {"geneset":"GSE9946_LISTERIA_INF_MATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9946_LISTERIA_INF_MATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN","description":"Genes down-regulated in mature inhibitory dendritic cells: L. monocytogenes infection versus prostaglandin E2 [PubChem=5280360]."} {"geneset":"GSE12484_HEALTHY_VS_PERIDONTITIS_NEUTROPHILS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12484_HEALTHY_VS_PERIDONTITIS_NEUTROPHILS_DN","description":"Genes down-regulated in neutrophils isolated from: healthy versus patients with peridontitis."} {"geneset":"GSE12484_HEALTHY_VS_PERIDONTITIS_NEUTROPHILS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12484_HEALTHY_VS_PERIDONTITIS_NEUTROPHILS_UP","description":"Genes up-regulated in neutrophils isolated from: healthy versus patients with peridontitis."} {"geneset":"GSE12707_AT16L1_HYPOMORPH_VS_WT_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12707_AT16L1_HYPOMORPH_VS_WT_THYMUS_DN","description":"Genes down-regulated in tymocytes: mutant (hypomorph) ATG16L1 [GeneID=55054] versus wildtype."} {"geneset":"GSE12707_AT16L1_HYPOMORPH_VS_WT_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12707_AT16L1_HYPOMORPH_VS_WT_THYMUS_UP","description":"Genes up-regulated in tymocytes: mutant (hypomorph) ATG16L1 [GeneID=55054] versus wildtype."} {"geneset":"GSE12505_WT_VS_E2_2_HET_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12505_WT_VS_E2_2_HET_PDC_UP","description":"Genes up-regulated in plasmacytoid dendritic cells: wildtype versus TCF4 [GeneID=6925] heterozygous knockout."} {"geneset":"GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP","description":"Genes up-regulated in CAL1 cells (plasmacytoid dendritic cells) versus MOLT4 (immature T cells)."} {"geneset":"GSE12505_WT_VS_E2_2_HET_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12505_WT_VS_E2_2_HET_PDC_DN","description":"Genes down-regulated in plasmacytoid dendritic cells: wildtype versus TCF4 [GeneID=6925] heterozygous knockout."} {"geneset":"GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_DN","description":"Genes down-regulated in CAL1 cells (plasmacytoid dendritic cells) versus MOLT4 (immature T cells)."} {"geneset":"GSE12839_CTRL_VS_IL12_TREATED_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12839_CTRL_VS_IL12_TREATED_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PBMC): control versus IL-12 stimulation."} {"geneset":"GSE12839_CTRL_VS_IL12_TREATED_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12839_CTRL_VS_IL12_TREATED_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PBMC): control versus IL-12 stimulation."} {"geneset":"GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP","description":"Genes up-regulated in control CD4 [GeneID=920] T cells versus those infected with HIV-1 viruses lacking Env, Vpr and Nef."} {"geneset":"GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN","description":"Genes down-regulated in control CD4 [GeneID=920] T cells versus those infected with HIV-1 viruses lacking Env, Vpr and Nef."} {"geneset":"GSE12963_UNINF_VS_ENV_AND_NEF_DEFICIENT_HIV1_INF_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12963_UNINF_VS_ENV_AND_NEF_DEFICIENT_HIV1_INF_CD4_TCELL_UP","description":"Genes up-regulated in control CD4 [GeneID=920] T cells versus those infected with HIV-1 viruses lacking Env and Nef."} {"geneset":"GSE12963_UNINF_VS_ENV_AND_NEF_DEFICIENT_HIV1_INF_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12963_UNINF_VS_ENV_AND_NEF_DEFICIENT_HIV1_INF_CD4_TCELL_DN","description":"Genes down-regulated in control CD4 [GeneID=920] T cell versus those infected with HIV-1 viruses lacking Env and Nef."} {"geneset":"GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells infected with Env/Nef deficient HIV-1 viruses versus those infected with HIV-1 viruses lacking Env, Nef and Vpr."} {"geneset":"GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells infected with Env/Nef deficient HIV-1 viruses versus those infected with HIV-1 viruses lacking Env, Nef and Vpr."} {"geneset":"GSE11367_CTRL_VS_IL17_TREATED_SMOOTH_MUSCLE_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11367_CTRL_VS_IL17_TREATED_SMOOTH_MUSCLE_CELL_UP","description":"Genes up-regulated in vascular smooth muscle cells: control versus treated with IL17A [GeneID=3605]."} {"geneset":"GSE11367_CTRL_VS_IL17_TREATED_SMOOTH_MUSCLE_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11367_CTRL_VS_IL17_TREATED_SMOOTH_MUSCLE_CELL_DN","description":"Genes down-regulated in vascular smooth muscle cells: control versus treated with IL17A [GeneID=3605]."} {"geneset":"GSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: control versus IL6 [GeneID=3569]."} {"geneset":"GSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: control versus IL6 [GeneID=3569]."} {"geneset":"GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_UP","description":"Genes up-regulated in splenocytes from OT-1 TCR transgenic mice: control versus IL-12 treatment."} {"geneset":"GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_DN","description":"Genes down-regulated in splenocytes from OT-1 TCR transgenic mice: control versus IL-12 treatment."} {"geneset":"GSE14413_UNSTIM_VS_IFNB_STIM_NIH3T3_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14413_UNSTIM_VS_IFNB_STIM_NIH3T3_CELLS_UP","description":"Genes up-regulated in NIH3T3 cells (fibroblast): control versus stimulated with IFN-b."} {"geneset":"GSE14413_UNSTIM_VS_IFNB_STIM_RAW264_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14413_UNSTIM_VS_IFNB_STIM_RAW264_CELLS_UP","description":"Genes up-regulated in RAW264.7 cells (macrophage): control versus stimulated with IFN-b."} {"geneset":"GSE14413_UNSTIM_VS_IFNB_STIM_RAW264_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14413_UNSTIM_VS_IFNB_STIM_RAW264_CELLS_DN","description":"Genes down-regulated in RAW264.7 cells (macrophage): control versus stimulated with IFN-b."} {"geneset":"GSE14413_UNSTIM_VS_IFNB_STIM_NIH3T3_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14413_UNSTIM_VS_IFNB_STIM_NIH3T3_CELLS_DN","description":"Genes down-regulated in NIH3T3 cells (fibroblast): control versus stimulated with IFN-b."} {"geneset":"GSE14413_UNSTIM_VS_IFNB_STIM_L929_CELLS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14413_UNSTIM_VS_IFNB_STIM_L929_CELLS_DN","description":"Genes down-regulated in L929 cells (fibroblast): control versus stimulated with IFN-b."} {"geneset":"GSE14413_UNSTIM_VS_IFNB_STIM_L929_CELLS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14413_UNSTIM_VS_IFNB_STIM_L929_CELLS_UP","description":"Genes up-regulated in L929 cells (fibroblast): control versus stimulated with IFN-b."} {"geneset":"GSE13887_ACT_CD4_VS_NO_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13887_ACT_CD4_VS_NO_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from healthy donors: activated by anti-CD3 and anti-CD28 versus nitric oxide [PubChem=145068] treatment."} {"geneset":"GSE13887_HEALTHY_VS_LUPUS_RESTING_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13887_HEALTHY_VS_LUPUS_RESTING_CD4_TCELL_DN","description":"Genes down-regulated in resting CD4 [GeneID=920] T cells: healthy versus systemic lupus erythrematosus (SLE)."} {"geneset":"GSE13887_RESTING_VS_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13887_RESTING_VS_ACT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from healthy donors: resting versus activated by anti-CD3 and anti-CD28."} {"geneset":"GSE13887_RESTING_VS_NO_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13887_RESTING_VS_NO_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from healthy donors: resting versus nitric oxide [PubChem=145068]."} {"geneset":"GSE13887_ACT_CD4_VS_NO_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13887_ACT_CD4_VS_NO_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from healthy donors: activated by anti-CD3 and anti-CD28 versus nitric oxide [PubChem=145068] treatment."} {"geneset":"GSE13887_RESTING_VS_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13887_RESTING_VS_ACT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from healthy donors: resting versus activated by anti-CD3 and anti-CD28."} {"geneset":"GSE13887_RESTING_VS_NO_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13887_RESTING_VS_NO_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from healthy donors: resting versus nitric oxide [PubChem=145068]."} {"geneset":"GSE13887_HEALTHY_VS_LUPUS_RESTING_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13887_HEALTHY_VS_LUPUS_RESTING_CD4_TCELL_UP","description":"Genes up-regulated in resting CD4 [GeneID=920] T cells: healthy versus systemic lupus erythrematosus (SLE)."} {"geneset":"GSE13762_CTRL_VS_125_VITAMIND_DAY5_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13762_CTRL_VS_125_VITAMIND_DAY5_DC_DN","description":"Genes down-regulated in dendritic cells (5 days): control versus 25-hydroxyvitamin D3 [PubChem=1593]."} {"geneset":"GSE13762_CTRL_VS_125_VITAMIND_DAY12_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13762_CTRL_VS_125_VITAMIND_DAY12_DC_UP","description":"Genes up-regulated in dendritic cells (12 days): control versus 25-hydroxyvitamin D3 [PubChem=1593]."} {"geneset":"GSE13762_CTRL_VS_125_VITAMIND_DAY5_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13762_CTRL_VS_125_VITAMIND_DAY5_DC_UP","description":"Genes up-regulated in dendritic cells (5 days): control versus 25-hydroxyvitamin D3 [PubChem=1593]."} {"geneset":"GSE13762_CTRL_VS_125_VITAMIND_DAY12_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13762_CTRL_VS_125_VITAMIND_DAY12_DC_DN","description":"Genes down-regulated in dendritic cells (12 days): control versus 25-hydroxyvitamin D3 [PubChem=1593]."} {"geneset":"GSE13522_WT_VS_IFNG_KO_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_WT_VS_IFNG_KO_SKIN_DN","description":"Genes down-regulated in skin from: wildtype (BALB/c) versus IFNG [GeneID=3458] knockout."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_UP","description":"Genes up-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain Y)."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_BRAZIL_STRAIN_INF_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_BRAZIL_STRAIN_INF_SKIN_UP","description":"Genes up-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain Brazil)."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNG_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNG_KO_DN","description":"Genes down-regulated in skin from INFG [GeneID=3458] knockout mice after injection of: control versus Trypanosoma cruzi (strain Y)."} {"geneset":"GSE13522_WT_VS_IFNG_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_WT_VS_IFNG_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP","description":"Genes up-regulated in skin after injection of Trypanosoma cruzi (strain Y): wildtype (BALB/c) versus INFG [GeneID=3458] knockout."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_G_STRAIN_INF_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_G_STRAIN_INF_SKIN_DN","description":"Genes down-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain G)."} {"geneset":"GSE13522_WT_VS_IFNG_KO_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_WT_VS_IFNG_KO_SKIN_UP","description":"Genes up-regulated in skin from: wildtype (BALB/c) versus IFNG [GeneID=3458] knockout."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNG_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNG_KO_UP","description":"Genes up-regulated in skin from INFG [GeneID=3458] knockout mice after injection of: control versus Trypanosoma cruzi (strain Y)."} {"geneset":"GSE13522_WT_VS_IFNG_KO_SKING_T_CRUZI_Y_STRAIN_INF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_WT_VS_IFNG_KO_SKING_T_CRUZI_Y_STRAIN_INF_DN","description":"Genes down-regulated in skin after injection of Trypanosoma cruzi (strain Y): wildtype (BALB/c) versus INFG [GeneID=3458] knockout."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_UP","description":"Genes up-regulated in skin from 129S1 mice after injection of: control versus Trypanosoma cruzi (strain Y)."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN","description":"Genes down-regulated in skin from 129S1 mice after injection of: control versus Trypanosoma cruzi (strain Y)."} {"geneset":"GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_DN","description":"Genes down-regulated in skin after injection of Trypanosoma cruzi (strain Y): wildtype (BALB/c) versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_BRAZIL_STRAIN_INF_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_BRAZIL_STRAIN_INF_SKIN_DN","description":"Genes down-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain Brazil)."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_G_STRAIN_INF_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_G_STRAIN_INF_SKIN_UP","description":"Genes up-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain G)."} {"geneset":"GSE13522_WT_VS_IFNAR_KO_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_WT_VS_IFNAR_KO_SKIN_DN","description":"Genes down-regulated in skin: wildtype (BALB/c) versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN","description":"Genes down-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain Y)."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_UP","description":"Genes up-regulated in skin after injection of Trypanosoma cruzi (strain Y): wildtype (129S1) versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_DN","description":"Genes down-regulated in skin after injection of Trypanosoma cruzi (strain Y): wildtype (129S1) versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE13522_WT_VS_IFNAR_KO_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_WT_VS_IFNAR_KO_SKIN_UP","description":"Genes up-regulated in skin: wildtype (BALB/c) versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP","description":"Genes up-regulated in skin after injection of Trypanosoma cruzi (strain Y): wildtype (BALB/c) versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus activated."} {"geneset":"GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus undergoing deletional tolerance."} {"geneset":"GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus undergoing deletional tolerance."} {"geneset":"GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: undergoing deletional tolerance versus activated."} {"geneset":"GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus activated."} {"geneset":"GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: undergoing deletional tolerance versus activated."} {"geneset":"GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_DN","description":"Genes down-regulated in gamma delta intraepithelial lymphocytes from colon: control versus colitis induced by dextran sulfate sodium (DSS)."} {"geneset":"GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP","description":"Genes up-regulated in gamma delta intraepithelial lymphocytes from colon: control versus colitis induced by dextran sulfate sodium (DSS)."} {"geneset":"GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP","description":"Genes up-regulated in activated T lymphocytes: T conv versus natural T reg."} {"geneset":"GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_DN","description":"Genes down-regulated in induced T reg: wildtype versus non-functional FOXP3 [GeneID=50943]."} {"geneset":"GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP","description":"Genes up-regulated in natural T reg with non-functional FOXP3 [GeneID=50943] versus T conv."} {"geneset":"GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_DN","description":"Genes down-regulated in activated T lymphocytes: T conv versus natural T reg."} {"geneset":"GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_UP","description":"Genes up-regulated in induced T reg: wildtype versus non-functional FOXP3 [GeneID=50943]."} {"geneset":"GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN","description":"Genes down-regulated in T reg: induced versus failed induced."} {"geneset":"GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN","description":"Genes down-regulated in natural T reg with non-functional FOXP3 [GeneID=50943] versus T conv."} {"geneset":"GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_UP","description":"Genes up-regulated in induced T reg cultured with IL2 [GeneID=3558]: wildtype versus non-functional FOXP3 [GeneID=50943]."} {"geneset":"GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_UP","description":"Genes up-regulated in T reg: induced versus failed induced."} {"geneset":"GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_DN","description":"Genes down-regulated in induced T reg cultured with IL2 [GeneID=3558]: wildtype versus non-functional FOXP3 [GeneID=50943]."} {"geneset":"GSE14415_INDUCED_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_TREG_VS_TCONV_UP","description":"Genes up-regulated in induced T reg versus T conv."} {"geneset":"GSE14415_INDUCED_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_TREG_VS_TCONV_DN","description":"Genes down-regulated in induced T reg versus T conv."} {"geneset":"GSE14415_NATURAL_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_NATURAL_TREG_VS_TCONV_DN","description":"Genes down-regulated in natural T reg versus T conv."} {"geneset":"GSE14415_ACT_VS_CTRL_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_ACT_VS_CTRL_NATURAL_TREG_DN","description":"Genes down-regulated in natural T reg: activated versus naü¾™¦”¼ve."} {"geneset":"GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_UP","description":"Genes up-regulated in T conv versus induced T reg with non-functional FOXP3 [GeneID=50943]."} {"geneset":"GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP","description":"Genes up-regulated in natural T reg: wildtype versus non-functional FOXP3 [GeneID=50943]."} {"geneset":"GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_DN","description":"Genes down-regulated in T conv versus induced T reg with non-functional FOXP3 [GeneID=50943]."} {"geneset":"GSE14415_INDUCED_VS_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_VS_NATURAL_TREG_UP","description":"Genes up-regulated in T reg: induced versus natural."} {"geneset":"GSE14415_INDUCED_VS_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_INDUCED_VS_NATURAL_TREG_DN","description":"Genes down-regulated in T reg: induced versus natural."} {"geneset":"GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN","description":"Genes down-regulated in natural T reg: wildtype versus non-functional FOXP3 [GeneID=50943]."} {"geneset":"GSE14415_ACT_VS_CTRL_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_ACT_VS_CTRL_NATURAL_TREG_UP","description":"Genes up-regulated in natural T reg: activated versus naü¾™¦”¼ve."} {"geneset":"GSE14415_NATURAL_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14415_NATURAL_TREG_VS_TCONV_UP","description":"Genes up-regulated in natural T reg versus T conv."} {"geneset":"GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_UP","description":"Genes up-regulated in peripheral blood mononclear cells (PBMC) from multiple sclerosis (MS) patient: untreated versus IFNB1 [GeneID=3456]."} {"geneset":"GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_DN","description":"Genes down-regulated in peripheral blood mononclear cells (PBMC) from multiple sclerosis (MS) patient: untreated versus IFNB1 [GeneID=3456]."} {"geneset":"GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_DN","description":"Genes down-regulated in B lymphocytes: control versus stimulated by anti-IgM for 12h."} 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{"geneset":"GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_DN","description":"Genes down-regulated in B lymphocytes: control versus stimulated by anti-IgM."} {"geneset":"GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP","description":"Genes up-regulated in B lymphocytes: control versus stimulated by anti-IgM for 2h."} {"geneset":"GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_UP","description":"Genes up-regulated in B lymphocytes stimulated by anti-IgM for 2h: wildtype versus ZFX [GeneID=7543] knockout."} {"geneset":"GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP","description":"Genes up-regulated 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{"geneset":"GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_UP","description":"Genes up-regulated in B lymphocytes: ZFX [GeneID=7543] knockout versus wildtype cells stimulated by anti-IgM for 12h."} {"geneset":"GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN","description":"Genes down-regulated in B lymphocytes: ZFX [GeneID=7543] knockout versus wildtype cells stimulated by anti-IgM for 12h."} {"geneset":"GSE13547_WT_VS_ZFX_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE13547_WT_VS_ZFX_KO_BCELL_DN","description":"Genes down-regulated in B lymphocytes: wildtype versus ZFX [GeneID=7543]."} {"geneset":"GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP","description":"Genes up-regulated in hematopoietic stem cells versus megakaryo-erythrocyte progenitors."} {"geneset":"GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN","description":"Genes down-regulated in hematopoietic stem cells versus lymphoid primed multipotent progenitors."} {"geneset":"GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN","description":"Genes down-regulated in hematopoietic stem cells versus megakaryo-erythrocyte progenitors."} {"geneset":"GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","description":"Genes up-regulated in megakaryo-erythrocyte progenitors versus granulo-monocyte progenitors."} {"geneset":"GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP","description":"Genes up-regulated in IKZF1 [GeneID=10320] knockout: lymphoid-primed multipotent progenitors versus megakaryo-erythrocyte progenitors."} {"geneset":"GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN","description":"Genes down-regulated in IKZF1 [GeneID=10320] 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{"geneset":"GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP","description":"Genes up-regulated in hematopoietic stem cells versus lymphoid primed multipotent progenitors."} {"geneset":"GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN","description":"Genes down-regulated in lymphoid-primed multipotent progenitors versus megakaryo-erythrocyte progenitors."} {"geneset":"GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP","description":"Genes up-regulated in IKZF1 [GeneID=10320] knockout: hematopoietic stem cells versus megakaryo-erythrocyte progenitors."} {"geneset":"GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","description":"Genes up-regulated in lymphoid-primed multipotent progenitors versus granulo-monocyte progenitors."} {"geneset":"GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP","description":"Genes up-regulated in IKZF1 [GeneID=10320] knockout: hematopoietic stem cells versus granulo-monocyte progenitors."} {"geneset":"GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN","description":"Genes down-regulated in IKZF1 [GeneID=10320] knockout: hematopoietic stem cells versus granulo-monocyte progenitors."} {"geneset":"GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","description":"Genes down-regulated in megakaryo-erythrocyte progenitors versus granulo-monocyte progenitors."} {"geneset":"GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","description":"Genes up-regulated in granulo-monocyte progenitors: wildtype versus IKZF1 [GeneID=10320] knockout."} {"geneset":"GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","description":"Genes down-regulated in granulo-monocyte progenitors: wildtype versus IKZF1 [GeneID=10320] knockout."} {"geneset":"GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP","description":"Genes up-regulated in lymphoid-primed multipotent progenitors versus megakaryo-erythrocyte progenitors."} {"geneset":"GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN","description":"Genes down-regulated in IKZF1 [GeneID=10320] knockout: megakaryo-erythrocyte progenitors versus granulo-monocyte progenitors."} {"geneset":"GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_DN","description":"Genes down-regulated in IKZF1 [GeneID=10320] knockout: hematopoietic stem 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{"geneset":"GSE15330_WT_VS_IKAROS_KO_HSC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_WT_VS_IKAROS_KO_HSC_UP","description":"Genes up-regulated in hematopoietic stem cells: wildtype versus IKZF1 [GeneID=10320] knockout."} {"geneset":"GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_UP","description":"Genes up-regulated in granulo-monocyte progenitors versus pro-B lymphocytes."} {"geneset":"GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_DN","description":"Genes down-regulated in granulo-monocyte progenitors versus pro-B lymphocytes."} {"geneset":"GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP","description":"Genes up-regulated in IKZF1 [GeneID=10320] knockout: megakaryo-erythrocyte progenitors versus granulo-monocyte progenitors."} {"geneset":"GSE15330_WT_VS_IKAROS_KO_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_WT_VS_IKAROS_KO_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN","description":"Genes down-regulated in megakaryo-erythrocyte progenitors: wildtype versus IKZF1 [GeneID=10320] knockout."} {"geneset":"GSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_DN","description":"Genes down-regulated in megakaryo-erythrocyte progenitors versus pro-B lymphocytes."} {"geneset":"GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP","description":"Genes up-regulated in IKZF1 [GeneID=10320] knockout: lymphoid-primed multipotent progenitors versus granulo-monocyte progenitors."} {"geneset":"GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN","description":"Genes down-regulated in IKZF1 [GeneID=10320] knockout: lymphoid-primed multipotent progenitors versus granulo-monocyte progenitors."} {"geneset":"GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_UP","description":"Genes up-regulated in IKZF1 [GeneID=10320] knockout: hematopoietic stem cells versus lymphoid-primed multipotent progenitors."} {"geneset":"GSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_UP","description":"Genes up-regulated in megakaryo-erythrocyte progenitors versus pro-B lymphocytes."} {"geneset":"GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","description":"Genes down-regulated in hematopoietic stem cells versus granulo-monocyte progenitors."} {"geneset":"GSE15330_HSC_VS_PRO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_PRO_BCELL_UP","description":"Genes up-regulated in hematopoietic stem cells versus pro-B lymphocytes."} {"geneset":"GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_DN","description":"Genes down-regulated in lymphoid-primed multipotent progenitors: wildtype versus IKZF1 [GeneID=10320] knockout."} {"geneset":"GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","description":"Genes down-regulated in lymphoid-primed multipotent progenitors versus granulo-monocyte progenitors."} {"geneset":"GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","description":"Genes up-regulated in hematopoietic stem cells versus granulo-monocyte progenitors."} {"geneset":"GSE15330_HSC_VS_PRO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15330_HSC_VS_PRO_BCELL_DN","description":"Genes down-regulated in hematopoietic stem cells versus pro-B lymphocytes."} {"geneset":"GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_UP","description":"Genes up-regulated in NK cells: low dose versus high dose of IL2 [GeneID=3558]."} {"geneset":"GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_DN","description":"Genes down-regulated in NK cells: primary versus activated and expanded."} {"geneset":"GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_DN","description":"Genes down-regulated in NK cells: low dose versus high dose of IL2 [GeneID=3558]."} {"geneset":"GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_UP","description":"Genes up-regulated in NK cells: primary versus stimulated by high dose of IL2 [GeneID=3558]."} {"geneset":"GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_DN","description":"Genes down-regulated in NK cells: primary versus stimulated by high dose of IL2 [GeneID=3558]."} {"geneset":"GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP","description":"Genes up-regulated in NK cells: primary versus activated and expanded."} {"geneset":"GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_UP","description":"Genes up-regulated in NK cells: primary versus stimulated by low dose of IL2 [GeneID=3558]."} {"geneset":"GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_DN","description":"Genes down-regulated in NK cells: primary versus stimulated by low dose of IL2 [GeneID=3558]."} {"geneset":"GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from atopic patients: resting versus stimulated with allergen (house dust mite)."} {"geneset":"GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from atopic patients: resting versus stimulated with allergen (house dust mite)."} {"geneset":"GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells from non-atopic donors: resting versus stimulated with allergen (house dust mite)."} {"geneset":"GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_DN","description":"Genes down-regulated in resting CD4 [GeneID=920] T cells: atopy versus healthy."} {"geneset":"GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells from non-atopic donors: resting versus stimulated with allergen (house dust mite)."} {"geneset":"GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_HDM_STIM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_HDM_STIM_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells stimulated with allergen (house dust mite): atopy versus healthy."} {"geneset":"GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_UP","description":"Genes up-regulated in resting CD4 [GeneID=920] T cells: atopy versus healthy."} {"geneset":"GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_HDM_STIM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_HDM_STIM_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells stimulated with allergen (house dust mite): atopy versus healthy."} {"geneset":"GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_DN","description":"Genes down-regulated in neutrophils treated with CSF2 [GeneID=1437] versus control."} {"geneset":"GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_UP","description":"Genes up-regulated in neutrophils treated with CSF2 [GeneID=1437] versus control."} {"geneset":"GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN","description":"Genes down-regulated in centroblasts versus centrocytes."} {"geneset":"GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_UP","description":"Genes up-regulated in centroblasts versus centrocytes."} {"geneset":"GSE15624_3H_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15624_3H_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with halofuginone [PubChem=400772]: 3h versus 6h."} {"geneset":"GSE15624_CTRL_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15624_CTRL_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: control versus treated with halofuginone [PubChem=400772] for 6h."} {"geneset":"GSE15624_3H_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15624_3H_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with halofuginone [PubChem=400772]: 3h versus 6h."} {"geneset":"GSE15624_CTRL_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15624_CTRL_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: control versus treated with halofuginone [PubChem=400772] for 6h."} {"geneset":"GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: control versus treated with halofuginone [PubChem=400772] for 3h."} {"geneset":"GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: control versus treated with halofuginone [PubChem=400772] for 3h."} {"geneset":"GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PMBC): healthy versus Gram negative sepsis."} {"geneset":"GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PMBC): healthy versus Gram negative sepsis."} {"geneset":"GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PMBC):healthy versus Gram positive sepsis."} {"geneset":"GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PMBC):healthy versus Gram positive sepsis."} {"geneset":"GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PMBC): healthy versus mixed infection sepsis."} {"geneset":"GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PMBC): healthy versus mixed infection sepsis."} {"geneset":"GSE9960_HEALTHY_VS_SEPSIS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_HEALTHY_VS_SEPSIS_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PMBC): healthy versus sepsis."} {"geneset":"GSE9960_HEALTHY_VS_SEPSIS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_HEALTHY_VS_SEPSIS_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PMBC): healthy versus sepsis."} {"geneset":"GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PMBC): Gram negative sepsis versus Gram positive sepsis."} {"geneset":"GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PMBC): Gram negative sepsis versus Gram positive sepsis."} {"geneset":"GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PMBC): Gram negative sepsis versus mixed infection sepsis."} {"geneset":"GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PMBC): Gram negative sepsis versus mixed infection sepsis."} {"geneset":"GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PMBC): Gram positive sepsis versus mixed infection sepsis."} {"geneset":"GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PMBC): Gram positive sepsis versus mixed infection sepsis."} {"geneset":"GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_DN","description":"Genes down-regulated in splenic dendritic cells from IFNB1 [GeneID=3456] knockout mice: CD8A+ [GeneID=925] versus CD8A- [GeneID=925] populations."} {"geneset":"GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_UP","description":"Genes up-regulated in wildtype splenic dendritic cells: CD8A+ [GeneID=925] versus CD8A- [GeneID=925]."} {"geneset":"GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_DN","description":"Genes down-regulated in CD8A- [GeneID=925] splenic dendritic cells: IFNAR1 [GeneID=3454] knockout versus IFNB1 [GeneID=3456] knockout."} {"geneset":"GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_UP","description":"Genes up-regulated in splenic dendritic cells from IFNB1 [GeneID=3456] knockout mice: CD8A+ [GeneID=925] versus CD8A- [GeneID=925] populations."} {"geneset":"GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_DN","description":"Genes down-regulated in CD8A- [GeneID=925] splenic dendritic cells: wildtype versus IFNAR1 [GeneID=3454] knockout mice."} {"geneset":"GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_UP","description":"Genes up-regulated in CD8A- [GeneID=925] splenic dendritic cells: IFNAR1 [GeneID=3454] knockout versus IFNB1 [GeneID=3456] knockout."} {"geneset":"GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN","description":"Genes down-regulated in wildtype splenic dendritic cells: CD8A+ [GeneID=925] versus CD8A- [GeneID=925]."} {"geneset":"GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN","description":"Genes down-regulated in CD8A+ [GeneID=925] splenic dendritic cells: wildtype versus IFNB1 [GeneID=3456] knockout mice."} {"geneset":"GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_UP","description":"Genes up-regulated in CD8A- [GeneID=925] splenic dendritic cells: wildtype versus IFNAR1 [GeneID=3454] knockout mice."} {"geneset":"GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP","description":"Genes up-regulated in CD8A- [GeneID=925] splenic dendritic cells: wildtype versus IFNB1 [GeneID=3456] knockout mice."} {"geneset":"GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN","description":"Genes down-regulated in CD8A- [GeneID=925] splenic dendritic cells: wildtype versus IFNB1 [GeneID=3456] knockout mice."} {"geneset":"GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_UP","description":"Genes up-regulated in CD8A+ [GeneID=925] splenic dendritic cells: wildtype versus IFNB1 [GeneID=3456] knockout mice."} {"geneset":"GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells versus follicular helper CD4 [GeneID=920] T cells."} {"geneset":"GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells versus follicular helper CD4 [GeneID=920] T cells."} {"geneset":"GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: control versus treated with HDAC inhibitors for 2h."} {"geneset":"GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: control versus treated with HDAC inhibitors for 12h."} {"geneset":"GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with HDAC inhibitors: 2h versus 12h."} {"geneset":"GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: control versus treated with HDAC inhibitors for 2h."} {"geneset":"GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with HDAC inhibitors: 2h versus 12h."} {"geneset":"GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: control versus treated with HDAC inhibitors for 12h."} {"geneset":"GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells: wildtype wt versus ZBTB7B [GeneID=51043] knockout."} {"geneset":"GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells: wildtype wt versus ZBTB7B [GeneID=51043] knockout."} {"geneset":"GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP","description":"Genes up-regulated in transitional B lymphocytes: CR2 [GeneID=1380] low versus CR2 [GeneID=1380] high."} {"geneset":"GSE17186_MEMORY_VS_NAIVE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_MEMORY_VS_NAIVE_BCELL_UP","description":"Genes up-regulated in B lymphocytes: memory versus naü¾™¦”¼ve."} {"geneset":"GSE17186_MEMORY_VS_NAIVE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_MEMORY_VS_NAIVE_BCELL_DN","description":"Genes down-regulated in B lymphocytes: memory versus naü¾™¦”¼ve."} {"geneset":"GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP","description":"Genes up-regulated in B lymphocytes from cord blood: naü¾™¦”¼ve versus transitional CR2 [GeneID=1380] high."} {"geneset":"GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN","description":"Genes down-regulated in transitional B lymphocytes: CR2 [GeneID=1380] low versus CR2 [GeneID=1380] high."} {"geneset":"GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_UP","description":"Genes up-regulated in B lymphocytes from cord blood: naü¾™¦”¼ve versus transitional CR2 [GeneID=1380]."} {"geneset":"GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_DN","description":"Genes down-regulated in B lymphocytes from cord blood: naü¾™¦”¼ve versus transitional CR2 [GeneID=1380]."} {"geneset":"GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve B lymphocytes versus those from cord blood."} {"geneset":"GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_UP","description":"Genes up-regulated in B lymphocytes: memory versus transitional CR2 [GeneID=1380] low."} {"geneset":"GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_DN","description":"Genes down-regulated in B lymphocytes: memory versus transitional CR2 [GeneID=1380] low."} {"geneset":"GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_UP","description":"Genes up-regulated in transitional CR2 [GeneID=1380] high B lymphocytes versus those from cord blood."} {"geneset":"GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_DN","description":"Genes down-regulated in transitional CR2 [GeneID=1380] high B lymphocytes versus those from cord blood."} {"geneset":"GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_DN","description":"Genes down-regulated in B lymphocytes: naü¾™¦”¼ve versus transitional CR2 [GeneID=1380] high."} {"geneset":"GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN","description":"Genes down-regulated in B lymphocytes from cord blood: naü¾™¦”¼ve versus transitional CR2 [GeneID=1380] high."} {"geneset":"GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP","description":"Genes up-regulated in transitional B lymphocytes from cord blood: CR2 [GeneID=1380] low versus CR2 [GeneID=1380] high."} {"geneset":"GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN","description":"Genes down-regulated in transitional B lymphocytes from cord blood: CR2 [GeneID=1380] low versus CR2 [GeneID=1380] high."} {"geneset":"GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve B lymphocytes versus those from cord blood."} {"geneset":"GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_UP","description":"Genes up-regulated in transitional CR2 [GeneID=1380] low B lymphocytes versus those from cord blood."} {"geneset":"GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_DN","description":"Genes down-regulated in transitional CR2 [GeneID=1380] low B lymphocytes versus those from cord blood."} {"geneset":"GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_DN","description":"Genes down-regulated in B lymphocytes: naü¾™¦”¼ve versus transitional CR2 [GeneID=1380] low."} {"geneset":"GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_UP","description":"Genes up-regulated in B lymphocytes: naü¾™¦”¼ve versus transitional CR2 [GeneID=1380] high."} {"geneset":"GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_UP","description":"Genes up-regulated in B lymphocytes: memory versus transitional CR2 [GeneID=1380] high."} {"geneset":"GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_DN","description":"Genes down-regulated in B lymphocytes: memory versus transitional CR2 [GeneID=1380] high."} {"geneset":"GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_UP","description":"Genes up-regulated in B lymphocytes: naü¾™¦”¼ve versus transitional CR2 [GeneID=1380] low."} {"geneset":"GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_UP","description":"Genes up-regulated in tumors established by injecting MC38 cells (colon cancer): control versus CpG oligodeoxynucleotide 1826."} {"geneset":"GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_DN","description":"Genes down-regulated in tumors established by injecting MC38 cells (colon cancer): control versus CpG oligodeoxynucleotide 1826."} {"geneset":"GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN","description":"Genes down-regulated inmouse embryonic fibroblasts (MEF): control versus LPS and heat shock."} {"geneset":"GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP","description":"Genes up-regulated in mouse embryonic fibroblasts (MEF): LPS versus LPS and heat shock."} {"geneset":"GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP","description":"Genes up-regulated inmouse embryonic fibroblasts (MEF): control versus LPS and heat shock."} {"geneset":"GSE16266_CTRL_VS_LPS_STIM_MEF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16266_CTRL_VS_LPS_STIM_MEF_DN","description":"Genes down-regulated in mouse embryonic fibroblasts (MEF): control versus LPS."} {"geneset":"GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN","description":"Genes down-regulated in mouse embryonic fibroblasts (MEF): LPS versus LPS and heat shock."} {"geneset":"GSE16266_CTRL_VS_LPS_STIM_MEF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16266_CTRL_VS_LPS_STIM_MEF_UP","description":"Genes up-regulated in mouse embryonic fibroblasts (MEF): control versus LPS."} {"geneset":"GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP","description":"Genes up-regulated in T cells: control (0h) versus IL21 [GeneID=59067] treatment for 6h."} {"geneset":"GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_DN","description":"Genes down-regulated in T cells: control (0h) versus IL21 [GeneID=59067] treatment for 1h."} {"geneset":"GSE19198_1H_VS_6H_IL21_TREATED_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_1H_VS_6H_IL21_TREATED_TCELL_UP","description":"Genes up-regulated in T cells treated with IL21 [GeneID=59067]: 1h versus 6h."} {"geneset":"GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_UP","description":"Genes up-regulated in T cells: control (0h) versus IL21 [GeneID=59067] treatment for 1h."} {"geneset":"GSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP","description":"Genes up-regulated in T cells treated with IL21 [GeneID=59067]: 6h versus 24h."} {"geneset":"GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN","description":"Genes down-regulated in T cells treated with IL21 [GeneID=59067]: 6h versus 24h."} {"geneset":"GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN","description":"Genes down-regulated in T cells: control (0h) versus IL21 [GeneID=59067] treatment for 6h."} {"geneset":"GSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN","description":"Genes down-regulated in T cells treated with IL21 [GeneID=59067]: 1h versus 24h."} {"geneset":"GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_DN","description":"Genes down-regulated in T cells: control (0h) versus IL21 [GeneID=59067] for 24h."} {"geneset":"GSE19198_1H_VS_6H_IL21_TREATED_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_1H_VS_6H_IL21_TREATED_TCELL_DN","description":"Genes down-regulated in T cells treated with IL21 [GeneID=59067]: 1h versus 6h."} {"geneset":"GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_UP","description":"Genes up-regulated in T cells: control (0h) versus IL21 [GeneID=59067] for 24h."} {"geneset":"GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP","description":"Genes up-regulated in T cells treated with IL21 [GeneID=59067]: 1h versus 24h."} {"geneset":"GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_UP","description":"Genes up-regulated in thymus cortical regions: subcapsular versus perimedullary."} {"geneset":"GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_DN","description":"Genes down-regulated in thymus cortical regions: subcapsular versus central cortical."} {"geneset":"GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_UP","description":"Genes up-regulated in cortical thymocytes versus thymus whole cortex."} {"geneset":"GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_DN","description":"Genes down-regulated in cortical thymocytes versus thymus whole cortex."} {"geneset":"GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_DN","description":"Genes down-regulated in thymus perimedullary cortical region versus the whole medulla."} {"geneset":"GSE18281_CORTEX_VS_MEDULLA_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_CORTEX_VS_MEDULLA_THYMUS_UP","description":"Genes up-regulated in thymus: whole cortex versus whole medulla."} {"geneset":"GSE18281_CORTEX_VS_MEDULLA_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_CORTEX_VS_MEDULLA_THYMUS_DN","description":"Genes down-regulated in thymus: whole cortex versus whole medulla."} {"geneset":"GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_UP","description":"Genes up-regulated in thymus cortical regions: subcapsular versus central cortical."} {"geneset":"GSE18281_MEDULLARY_THYMOCYTE_VS_WHOLE_MEDULLA_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_MEDULLARY_THYMOCYTE_VS_WHOLE_MEDULLA_THYMUS_UP","description":"Genes up-regulated in medullary thymocytes versus thymus whole medulla."} {"geneset":"GSE18281_MEDULLARY_THYMOCYTE_VS_WHOLE_MEDULLA_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_MEDULLARY_THYMOCYTE_VS_WHOLE_MEDULLA_THYMUS_DN","description":"Genes down-regulated in medullary thymocytes versus thymus whole medulla."} {"geneset":"GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP","description":"Genes up-regulated in thymus subcapsular cortical region versus the whole cortex."} {"geneset":"GSE18281_CORTICAL_VS_MEDULLARY_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_CORTICAL_VS_MEDULLARY_THYMOCYTE_UP","description":"Genes up-regulated in thymocytes: cortical versus medullary sources."} {"geneset":"GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP","description":"Genes up-regulated in thymus subcapsular cortical region versus the whole medulla."} {"geneset":"GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_DN","description":"Genes down-regulated in thymus subcapsular cortical region versus the whole medulla."} {"geneset":"GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP","description":"Genes up-regulated in thymus perimedullary cortical region versus the whole cortex."} {"geneset":"GSE18281_CORTICAL_VS_MEDULLARY_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_CORTICAL_VS_MEDULLARY_THYMOCYTE_DN","description":"Genes down-regulated in thymocytes: cortical versus medullary sources."} {"geneset":"GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP","description":"Genes up-regulated in thymus perimedullary cortical region versus the whole medulla."} {"geneset":"GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_DN","description":"Genes down-regulated in thymus cortical regions: subcapsular versus perimedullary."} {"geneset":"GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_DN","description":"Genes down-regulated in thymus subcapsular cortical region versus the whole cortex."} {"geneset":"GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_DN","description":"Genes down-regulated in thymus perimedullary cortical region versus the whole cortex."} {"geneset":"GSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: control versus Listeria infected."} {"geneset":"GSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: control versus Listeria infected."} {"geneset":"GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes: TCF3 [GeneID=6929] knockout versus TCF12 [GeneID=6938] knockout."} {"geneset":"GSE19923_WT_VS_E2A_KO_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_WT_VS_E2A_KO_DP_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes: wildtype versus TCF3 [GeneID=6929] knockout."} {"geneset":"GSE19923_WT_VS_E2A_KO_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_WT_VS_E2A_KO_DP_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes: wildtype versus TCF3 [GeneID=6929] knockout."} {"geneset":"GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes: wildtype versus TCF3 and TCF12 [GeneID=6929;6938] knockout."} {"geneset":"GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes: TCF12 [GeneID=6939] knockout versus TCF3 and TCF12 [GeneID=6929;6938] knockout."} {"geneset":"GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes: TCF12 [GeneID=6939] knockout versus TCF3 and TCF12 [GeneID=6929;6938] knockout."} {"geneset":"GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes: wildtype versus TCF3 and TCF12 [GeneID=6929;6938] knockout."} {"geneset":"GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes: TCF3 [GeneID=6929] knockout versus TCF12 [GeneID=6938] knockout."} {"geneset":"GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_UP","description":"Genes up-regulated in double positve thymocyte: TCF3 [GeneID=6929] knockout versus TCF3 and TCF12 [GeneID=6929;6938] knockout."} {"geneset":"GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN","description":"Genes down-regulated in double positve thymocyte: TCF3 [GeneID=6929] knockout versus TCF3 and TCF12 [GeneID=6929;6938] knockout."} {"geneset":"GSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes: wildtype versus TCF12 [GeneID=6938] knockout."} {"geneset":"GSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes: wildtype versus TCF12 [GeneID=6938] knockout."} {"geneset":"GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN","description":"Genes down-regulated in monocytes pre-treated with Ly294002 [PubChem=3973]: control versus HCMV infection."} {"geneset":"GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP","description":"Genes up-regulated in monocytes: control versus HCMV infection."} {"geneset":"GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP","description":"Genes up-regulated in monocytes after HCMV infection: untreated versus pre-treated with Ly294002 [PubChem=3973]."} {"geneset":"GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN","description":"Genes down-regulated in monocytes after HCMV infection: untreated versus pre-treated with Ly294002 [PubChem=3973]."} {"geneset":"GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_DN","description":"Genes down-regulated in monocytes: control versus HCMV infection."} {"geneset":"GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP","description":"Genes up-regulated in monocytes pre-treated with Ly294002 [PubChem=3973]: control versus HCMV infection."} {"geneset":"GSE18893_TCONV_VS_TREG_24H_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_TCONV_VS_TREG_24H_CULTURE_DN","description":"Genes down-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells."} {"geneset":"GSE18893_TCONV_VS_TREG_24H_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_TCONV_VS_TREG_24H_CULTURE_UP","description":"Genes up-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells."} {"geneset":"GSE18893_TCONV_VS_TREG_24H_TNF_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_TCONV_VS_TREG_24H_TNF_STIM_DN","description":"Genes down-regulated in lymphocytes treated with TNF [GeneID=7124] for 24h: T conv versus T reg cells."} {"geneset":"GSE18893_TCONV_VS_TREG_2H_CULTURE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_TCONV_VS_TREG_2H_CULTURE_DN","description":"Genes down-regulated in lymphocytes treated with medium for 2h: T conv versus T reg cells."} {"geneset":"GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP","description":"Genes up-regulated in T reg cells (2h): medium versus TNF [GeneID=7124]."} {"geneset":"GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_UP","description":"Genes up-regulated in T conv cells (2h): medium versus TNF [GeneID=7124]."} {"geneset":"GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_DN","description":"Genes down-regulated in T reg cells: 2h versus 24h medium treatment."} {"geneset":"GSE18893_TCONV_VS_TREG_2H_TNF_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_TCONV_VS_TREG_2H_TNF_STIM_UP","description":"Genes up-regulated in lymphocytes treated with TNF [GeneID=7124] for 2h: T conv versus T reg cells."} {"geneset":"GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_UP","description":"Genes up-regulated in T reg cells: 2h versus 24h medium treatment."} {"geneset":"GSE18893_TCONV_VS_TREG_2H_CULTURE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_TCONV_VS_TREG_2H_CULTURE_UP","description":"Genes up-regulated in lymphocytes treated with medium for 2h: T conv versus T reg cells."} {"geneset":"GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_DN","description":"Genes down-regulated in T conv cells (2h): medium versus TNF [GeneID=7124]."} {"geneset":"GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_DN","description":"Genes down-regulated in T reg cells (2h): medium versus TNF [GeneID=7124]."} {"geneset":"GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_UP","description":"Genes up-regulated in T conv cells (24h): medium versus TNF [GeneID=7124]."} {"geneset":"GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_DN","description":"Genes down-regulated in T conv cells (24h): medium versus TNF [GeneID=7124]."} {"geneset":"GSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN","description":"Genes down-regulated in lymphocytes treated with TNF [GeneID=7124] for 2h: T conv versus T reg cells."} {"geneset":"GSE18893_TCONV_VS_TREG_24H_TNF_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18893_TCONV_VS_TREG_24H_TNF_STIM_UP","description":"Genes up-regulated in lymphocytes treated with TNF [GeneID=7124] for 24h: T conv versus T reg cells."} {"geneset":"GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: untreated versus incubated with the peptide ALL1."} {"geneset":"GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: untreated versus incubated with the peptide ALL1."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells incubated with the peptide ALL1 followed by treatment with: Cl-IB-MECA [PubChem=3035850] versus T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: Cl-IB-MECA [PubChem=3035850] versus incubated with the ALL1 peptide followed by treatment with Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: Cl-IB-MECA [PubChem=3035850] versus T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: Cl-IB-MECA [PubChem=3035850] versus incubated with the peptide ALL1 followed by stimulation with T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: Cl-IB-MECA [PubChem=3035850] versus incubated with the peptide ALL1 followed by stimulation with T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: incubated with the peptide ALL1 and then treated with Cl-IB-MECA [PubChem=3035850] versus stimulation by T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: incubated with the peptide ALL1 and then treated with Cl-IB-MECA [PubChem=3035850] versus stimulation by T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells incubated the peptide ALL1 versus those followed by treatment with Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells incubated the peptide ALL1 versus those followed by treatment with Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: incubated with the peptide ALL1 versus stimulated with T cell membranes."} {"geneset":"GSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: untreated versus Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: untreated versus Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_CTRL_VS_A3R_ACT_TREATED_MAST_CELL_PRETREATED_WITH_A3R_INH_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_A3R_ACT_TREATED_MAST_CELL_PRETREATED_WITH_A3R_INH_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: untreated versus incubated with the peptide ALL1 followed by treatment with Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: Cl-IB-MECA [PubChem=3035850] versus incubated with the ALL1 peptide followed by treatment with Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: Cl-IB-MECA [PubChem=3035850] versus T cell membranes."} {"geneset":"GSE19888_CTRL_VS_T_CELL_MEMBRANES_ACT_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_T_CELL_MEMBRANES_ACT_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: untreated versus stimulated with T cell membranes."} {"geneset":"GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: untreated versus incubated with the peptide ALL1 followed by stimulation with T cell membranes."} {"geneset":"GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: untreated versus incubated with the peptide ALL1 followed by stimulation with T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells incubated with: the peptide ALL1 versus Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells incubated with: the peptide ALL1 versus Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_VS_INH_PRETREAT_AND_ACT_WITH_TCELL_MEMBRANES_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_VS_INH_PRETREAT_AND_ACT_WITH_TCELL_MEMBRANES_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells incubated with the peptide ALL1 versus those then stimulated by T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_VS_INH_PRETREAT_AND_ACT_WITH_TCELL_MEMBRANES_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_VS_INH_PRETREAT_AND_ACT_WITH_TCELL_MEMBRANES_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells incubated with the peptide ALL1 versus those then stimulated by T cell membranes."} {"geneset":"GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: stimulated with T cell membranes versus incubated with the peptide ALL1 and then stimulated with T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_VS_TCELL_MEMBRANES_ACT_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_VS_TCELL_MEMBRANES_ACT_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: incubated with the peptide ALL1 versus stimulated with T cell membranes."} {"geneset":"GSE19888_CTRL_VS_A3R_ACT_TREATED_MAST_CELL_PRETREATED_WITH_A3R_INH_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_A3R_ACT_TREATED_MAST_CELL_PRETREATED_WITH_A3R_INH_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells: untreated versus incubated with the peptide ALL1 followed by treatment with Cl-IB-MECA [PubChem=3035850]."} {"geneset":"GSE19888_CTRL_VS_T_CELL_MEMBRANES_ACT_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_CTRL_VS_T_CELL_MEMBRANES_ACT_MAST_CELL_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: untreated versus stimulated with T cell membranes."} {"geneset":"GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_DN","description":"Genes down-regulated in HMC-1 (mast leukemia) cells incubated with the peptide ALL1 followed by treatment with: Cl-IB-MECA [PubChem=3035850] versus T cell membranes."} {"geneset":"GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_UP","description":"Genes up-regulated in HMC-1 (mast leukemia) cells: stimulated with T cell membranes versus incubated with the peptide ALL1 and then stimulated with T cell membranes."} {"geneset":"GSE25890_CTRL_VS_IL33_IL7_TREATED_NUOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25890_CTRL_VS_IL33_IL7_TREATED_NUOCYTES_DN","description":"Genes down-regulated in nuocytes: control versus treated with IL7 and IL33 [GeneID=3574;90865]."} {"geneset":"GSE25890_CTRL_VS_IL33_IL7_TREATED_NUOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25890_CTRL_VS_IL33_IL7_TREATED_NUOCYTES_UP","description":"Genes up-regulated in nuocytes: control versus treated with IL7 and IL33 [GeneID=3574;90865]."} {"geneset":"GSE20198_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_DN","description":"Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus IL-12."} {"geneset":"GSE20198_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_UP","description":"Genes up-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus IL-12."} {"geneset":"GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_UP","description":"Genes up-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus interferon alpha."} {"geneset":"GSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_UP","description":"Genes up-regulated in the activated CD4 [GeneID=920] T cells (48h): IL-12 versus interferon alpha."} {"geneset":"GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_DN","description":"Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): IL-12 and IL18 [GeneID=3606] versus interferon alpha."} {"geneset":"GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_UP","description":"Genes up-regulated in the activated CD4 [GeneID=920] T cells (48h): IL-12 and IL18 [GeneID=3606] versus interferon alpha."} {"geneset":"GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN","description":"Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): IL-12 versus IL-12 and IL18 [GeneID=3606]."} {"geneset":"GSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN","description":"Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus IL-12 and IL18 [GeneID=3606]."} {"geneset":"GSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_DN","description":"Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): IL-12 versus interferon alpha."} {"geneset":"GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_DN","description":"Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus interferon alpha."} {"geneset":"GSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP","description":"Genes up-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus IL-12 and IL18 [GeneID=3606]."} {"geneset":"GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP","description":"Genes up-regulated in the activated CD4 [GeneID=920] T cells (48h): IL-12 versus IL-12 and IL18 [GeneID=3606]."} {"geneset":"GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN","description":"Genes down-regulated in monocyte derived macrophages: CSF1 [GeneID=1435] versus PF4 [GeneID=5196]."} {"geneset":"GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_UP","description":"Genes up-regulated in monocyte derived macrophages: CSF1 [GeneID=1435] versus PF4 [GeneID=5196]."} {"geneset":"GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_UP","description":"Genes up-regulated in lung dendritic cells: CD103+ [GeneID=3682] versus CD11b [GeneID=3684] high."} {"geneset":"GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_DN","description":"Genes down-regulated in lungh dendritic cell : CD103+ [GeneID=3682] versus CD11b [GeneID=3684] high."} {"geneset":"GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_DN","description":"Genes down-regulated in T reg cells: wildtype versus FOXO1 and FOXO3 [GeneID=2308;2309]."} {"geneset":"GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_UP","description":"Genes up-regulated in T reg cells: wildtype versus FOXO1 and FOXO3 [GeneID=2308;2309]."} {"geneset":"GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP","description":"Genes up-regulated in the neuron cell line: immature versus mature."} {"geneset":"GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_DN","description":"Genes down-regulated in the neuron cell line: immature versus mature."} {"geneset":"GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP","description":"Genes up-regulated in immature neuron cell line: control versus interferon alpha (12h)."} {"geneset":"GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_DN","description":"Genes down-regulated in immature neuron cell line: control versus interferon alpha (12h)."} {"geneset":"GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_DN","description":"Genes down-regulated in neuron cell line infected with western equine encephalitis virus: immature versus mature cells."} {"geneset":"GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN","description":"Genes down-regulated in immature neuron cell line: control versus interferon alpha (6h)."} {"geneset":"GSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_UP","description":"Genes up-regulated in mature neuron cell line: control versus interferon alpha (12h)."} {"geneset":"GSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_DN","description":"Genes down-regulated in mature neuron cell line: control versus interferon alpha (12h)."} {"geneset":"GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_UP","description":"Genes up-regulated in neuron cell line infected with western equine encephalitis virus: immature versus mature cells."} {"geneset":"GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP","description":"Genes up-regulated in neuron cell line treated with interferon alpha for 6h: immature versus mature."} {"geneset":"GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_DN","description":"Genes down-regulated in neuron cell line treated with interferon alpha for 6h: immature versus mature."} {"geneset":"GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP","description":"Genes up-regulated in immature neuron cell line: control versus interferon alpha (6h)."} {"geneset":"GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_DN","description":"Genes down-regulated in neuron cell line treated with interferon alpha for 12h: immature versus mature."} {"geneset":"GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_UP","description":"Genes up-regulated in mature neuron cell line: control versus interferon alpha (6h)."} {"geneset":"GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_DN","description":"Genes down-regulated in mature neuron cell line: control versus interferon alpha (6h)."} {"geneset":"GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_UP","description":"Genes up-regulated in the mature neuron cell line: control versus infected with western equine encephalitis virus."} {"geneset":"GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN","description":"Genes down-regulated in the mature neuron cell line: control versus infected with western equine encephalitis virus."} {"geneset":"GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_UP","description":"Genes up-regulated in the immature neuron cell line: control versus infected with western equine encephalitis viruss."} {"geneset":"GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN","description":"Genes down-regulated in the immature neuron cell line: control versus infected with western equine encephalitis viruss."} {"geneset":"GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_UP","description":"Genes up-regulated in neuron cell line treated with interferon alpha for 12h: immature versus mature."} {"geneset":"GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: TGF beta versus IL6 [GeneID=3569]."} {"geneset":"GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: TGF beta versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: TGF beta versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_TGFB_VS_IL6_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_TGFB_VS_IL6_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: TGF beta versus IL6 [GeneID=3569]."} {"geneset":"GSE21670_TGFB_VS_IL6_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_TGFB_VS_IL6_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: TGF beta versus IL6 [GeneID=3569]."} {"geneset":"GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: medium versus IL6 [GeneID=3569]."} {"geneset":"GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with TGF beta: STAT3 [GeneID=6774] knockout versus wildtype."} {"geneset":"GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with TGF beta: STAT3 [GeneID=6774] knockout versus wildtype."} {"geneset":"GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: TGF beta versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: TGF beta versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: TGF beta versus IL6 [GeneID=3569]."} {"geneset":"GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: IL6 [GeneID=3569] versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: IL6 [GeneID=3569] versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with TGF beta and IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype."} {"geneset":"GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with TGF beta and IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype."} {"geneset":"GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: STAT3 [GeneID=6774] knockout versus wildtype."} {"geneset":"GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus IL6 [GeneID=3569]."} {"geneset":"GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus IL6 [GeneID=3569]."} {"geneset":"GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: medium versus IL6 [GeneID=3569]."} {"geneset":"GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: medium versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus TGF beta."} {"geneset":"GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: IL6 [GeneID=3569] versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: medium versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_STAT3_KO_VS_WT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_STAT3_KO_VS_WT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: STAT3 [GeneID=6774] knockout versus wildtype."} {"geneset":"GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype."} {"geneset":"GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: medium versus TGF beta."} {"geneset":"GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: medium versus TGF beta."} {"geneset":"GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: IL6 [GeneID=3569] versus TGF beta and IL6 [GeneID=3569]."} {"geneset":"GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus TGF beta."} {"geneset":"GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype."} {"geneset":"GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_UP","description":"Genes up-regulated in periperal blood monocytes (PBMC) from kidney transplant recipients: tolerant versus immunosuppressive therapy."} {"geneset":"GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN","description":"Genes down-regulated in periperal blood monocytes (PBMC): kidney transplant recipients receiving immunosuppression therapy versus healthy controls."} {"geneset":"GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN","description":"Genes down-regulated in periperal blood monocytes (PBMC): tolerant kidney transplants versus healthy controls."} {"geneset":"GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_UP","description":"Genes up-regulated in periperal blood monocytes (PBMC): kidney transplant recipients receiving immunosuppression therapy versus healthy controls."} {"geneset":"GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN","description":"Genes down-regulated in periperal blood monocytes (PBMC) from kidney transplant recipients: tolerant versus immunosuppressive therapy."} {"geneset":"GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_UP","description":"Genes up-regulated in periperal blood monocytes (PBMC): tolerant kidney transplants versus healthy controls."} {"geneset":"GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP","description":"Genes up-regulated in NCAM+ [GeneID=4684] NK cells: SELL bright [GeneID=6402] versus SELL dim [GeneID=6402]."} {"geneset":"GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP","description":"Genes up-regulated in NCAM1+ SELL bright [GeneID=4684;6402] versus NCAM1- SELL dim [GeneID=4684;6402]."} {"geneset":"GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP","description":"Genes up-regulated in SELL dim [GeneID=6402] NK cells: NCAM1+ [GeneID=4684] versus NCAM1- [GeneID=4684]."} {"geneset":"GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_DN","description":"Genes down-regulated in NCAM+ [GeneID=4684] NK cells: SELL bright [GeneID=6402] versus SELL dim [GeneID=6402]."} {"geneset":"GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN","description":"Genes down-regulated in NCAM1+ SELL bright [GeneID=4684;6402] versus NCAM1- SELL dim [GeneID=4684;6402]."} {"geneset":"GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN","description":"Genes down-regulated in SELL dim [GeneID=6402] NK cells: NCAM1+ [GeneID=4684] versus NCAM1- [GeneID=4684]."} {"geneset":"GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus wildtype Tfh cells."} {"geneset":"GSE21379_WT_VS_SAP_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21379_WT_VS_SAP_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] non-follicular helper T cells: wildtype versus SH2D1A [GeneID=4068] knockout."} {"geneset":"GSE21379_TFH_VS_NON_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21379_TFH_VS_NON_TFH_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) versus non-Tfh."} {"geneset":"GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus wildtype Tfh cells."} {"geneset":"GSE21380_NON_TFH_VS_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21380_NON_TFH_VS_TFH_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper)."} {"geneset":"GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper) from germinal center."} {"geneset":"GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper) from germinal center."} {"geneset":"GSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] Tfh (T follicular helper) cells: Tfh versus Tfh from germinal center."} {"geneset":"GSE21379_TFH_VS_NON_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21379_TFH_VS_NON_TFH_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) versus non-Tfh."} {"geneset":"GSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] Tfh (T follicular helper) cells: Tfh versus Tfh from germinal center."} {"geneset":"GSE21379_TFH_VS_NON_TFH_SAP_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21379_TFH_VS_NON_TFH_SAP_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus non-Tfh cells with SH2D1A [GeneID=4068] knockout."} {"geneset":"GSE21379_WT_VS_SAP_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21379_WT_VS_SAP_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] non-follicular helper T cells: wildtype versus SH2D1A [GeneID=4068] knockout."} {"geneset":"GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper)."} {"geneset":"GSE21379_TFH_VS_NON_TFH_SAP_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21379_TFH_VS_NON_TFH_SAP_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus non-Tfh cells with SH2D1A [GeneID=4068] knockout."} {"geneset":"GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN","description":"Genes down-regulated in untreated double positive thymocytes: wildtype versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP","description":"Genes up-regulated in double positive thymocytes stimulated by anti-CD3: wildtype versus ELK4 [GeneID=2005] knockout."} {"geneset":"GSE21546_WT_VS_ELK1_KO_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_ELK1_KO_DP_THYMOCYTES_UP","description":"Genes up-regulated in untreated double positive thymocytes: wildtype versus ELK1 [GeneID=2002] knockout."} {"geneset":"GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN","description":"Genes down-regulated in double positive thymocytes stimulated by anti-CD3: wildtype versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP","description":"Genes up-regulated in untreated double positive thymocytes: ELK4 [GeneID=2005] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN","description":"Genes down-regulated in untreated double positive thymocytes: ELK4 [GeneID=2005] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP","description":"Genes up-regulated in double positive thymocytes stimulated by anti-CD3: ELK4 [GeneID=2005] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN","description":"Genes down-regulated in double positive thymocytes stimulated by anti-CD3: ELK4 [GeneID=2005] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_WT_VS_ELK1_KO_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_ELK1_KO_DP_THYMOCYTES_DN","description":"Genes down-regulated in untreated double positive thymocytes: wildtype versus ELK1 [GeneID=2002] knockout."} {"geneset":"GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP","description":"Genes up-regulated in untreated double positive thymocytes: wildtype versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP","description":"Genes up-regulated in stimulated by anti-CD3 double positive thymocytes: 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untreated double positive thymocytes: wildtype versus ELK4 [GeneID=2005] knockout."} {"geneset":"GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_DN","description":"Genes down-regulated in untreated double positive thymocytes: wildtype versus ELK4 [GeneID=2005] knockout."} {"geneset":"GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP","description":"Genes up-regulated in untreated double positive thymocytes: ELK1 [GeneID=2002] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN","description":"Genes down-regulated in untreated double positive thymocytes: ELK1 [GeneID=2002] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_UP","description":"Genes up-regulated in double positive thymocytes: untreated versus stimulated by anti-CD3."} {"geneset":"GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_DN","description":"Genes down-regulated in double positive thymocytes: untreated versus stimulated by anti-CD3."} {"geneset":"GSE21546_UNSTIM_VS_ANTI_CD3_STIM_SAP1A_KO_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_UNSTIM_VS_ANTI_CD3_STIM_SAP1A_KO_DP_THYMOCYTES_UP","description":"Genes up-regulated in double positive thymocytes with ELK4 [GeneID=2005] knockout: untreated versus stimulated by anti-CD3."} {"geneset":"GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN","description":"Genes down-regulated in double positive thymocytes stimulated by anti-CD3: wildtype versus ELK1 [GeneID=2002] knockout."} {"geneset":"GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP","description":"Genes up-regulated in double positive thymocytes stimulated by anti-CD3: wildtype versus ELK1 and ELK4 [GeneID=2002;2005] knockout."} {"geneset":"GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_UP","description":"Genes up-regulated in CD11b BoneMarrow from BALBc mouse versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and IL-6."} {"geneset":"GSE21927_HEALTHY_VS_TUMOROUS_BALBC_MOUSE_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_HEALTHY_VS_TUMOROUS_BALBC_MOUSE_MONOCYTE_DN","description":"Genes down-regulated in CD11b+ cells from spleen of BALB/c mice: healthy versus bearing C26GM colon carcinoma."} {"geneset":"GSE21927_SPLEEN_VS_C26GM_TUMOR_MONOCYTE_BALBC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_C26GM_TUMOR_MONOCYTE_BALBC_UP","description":"Genes up-regulated in CD11b+ cells from BALB/c mice bearing C26GM colon carcinoma: spleen of BALB/c mice: spleen versus tumor infiltrating monocytes."} {"geneset":"GSE21927_HEALTHY_VS_TUMOROUS_BALBC_MOUSE_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_HEALTHY_VS_TUMOROUS_BALBC_MOUSE_MONOCYTE_UP","description":"Genes up-regulated in CD11b+ cells from spleen of BALB/c mice: healthy versus bearing C26GM colon carcinoma."} {"geneset":"GSE21927_SPLEEN_VS_4T1_TUMOR_MONOCYTE_BALBC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_4T1_TUMOR_MONOCYTE_BALBC_DN","description":"Genes down-regulated in CD11b+ cells from BALB/c mice bearing 4T1 mammary carcinoma: spleen of BALB/c mice: spleen versus tumor infiltrating monocytes."} {"geneset":"GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_UP","description":"Genes up-regulated in CD11b+ cells from BALB/c mice: spleen versus bone marrow."} {"geneset":"GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_UP","description":"Genes up-regulated in CD11b+ cells from BALB/c mice bearing: C26GM colon carcinoma versus 4T1 mammary carcinoma."} {"geneset":"GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_UP","description":"Genes up-regulated in CD11b Spleen from BALBc mouse versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and GCSF."} {"geneset":"GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN","description":"Genes down-regulated in CD11b Spleen from BALBc mouse versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and GCSF."} {"geneset":"GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_DN","description":"Genes down-regulated in CD11b BoneMarrow from BALBc mouse versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and IL-6."} {"geneset":"GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_DN","description":"Genes down-regulated in CD11b+ cells from BALB/c mice: spleen versus bone marrow."} {"geneset":"GSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_UP","description":"Genes up-regulated in spleen CD11b cells: BALBc versus C57BL6 mouse strains."} {"geneset":"GSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_DN","description":"Genes down-regulated in spleen CD11b cells: BALBc versus C57BL6 mouse strains."} {"geneset":"GSE21927_UNTREATED_VS_GMCSF_GCSF_TREATED_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_UNTREATED_VS_GMCSF_GCSF_TREATED_BONE_MARROW_DN","description":"Genes down-regulated in CD11b BoneMarrow from BALBc mouse versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and GCSF."} {"geneset":"GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_UP","description":"Genes up-regulated in CD11b BoneMarrow from BALBc mouse incubated with GMCSF and IL-6 versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and GCSF."} {"geneset":"GSE21927_SPLEEN_VS_C26GM_TUMOR_MONOCYTE_BALBC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_C26GM_TUMOR_MONOCYTE_BALBC_DN","description":"Genes down-regulated in CD11b+ cells from BALB/c mice bearing C26GM colon carcinoma: spleen of BALB/c mice: spleen versus tumor infiltrating monocytes."} {"geneset":"GSE21927_SPLEEN_VS_4T1_TUMOR_MONOCYTE_BALBC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_4T1_TUMOR_MONOCYTE_BALBC_UP","description":"Genes up-regulated in CD11b+ cells from BALB/c mice bearing 4T1 mammary carcinoma: spleen of BALB/c mice: spleen versus tumor infiltrating monocytes."} {"geneset":"GSE21927_BALBC_VS_C57BL6_MONOCYTE_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_BALBC_VS_C57BL6_MONOCYTE_TUMOR_DN","description":"Genes down-regulated in CD11b Tumor from BALBc mouse versus CD11b Tumor from C57BL6 mouse."} {"geneset":"GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_BALBC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_BALBC_UP","description":"Genes up-regulated in CD11b Spleen from BALBc mouse versus CD11b Tumor from BALBc mouse."} {"geneset":"GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_BALBC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_BALBC_DN","description":"Genes down-regulated in CD11b Spleen from BALBc mouse versus CD11b Tumor from BALBc mouse."} {"geneset":"GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_C57BL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_C57BL6_UP","description":"Genes up-regulated in CD11b Spleen from C57BL6 mouse versus CD11b Tumor from C57BL6 mouse."} {"geneset":"GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_C57BL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_C57BL6_DN","description":"Genes down-regulated in CD11b Spleen from C57BL6 mouse versus CD11b Tumor from C57BL6 mouse."} {"geneset":"GSE21927_EL4_VS_MCA203_TUMOR_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_EL4_VS_MCA203_TUMOR_MONOCYTES_UP","description":"Genes up-regulated in CD11b EL4 Tumor from C57BL6 mouse versus CD11b MCA203 Tumor from C57BL6 mouse."} {"geneset":"GSE21927_EL4_VS_MCA203_TUMOR_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_EL4_VS_MCA203_TUMOR_MONOCYTES_DN","description":"Genes down-regulated in CD11b EL4 Tumor from C57BL6 mouse versus CD11b MCA203 Tumor from C57BL6 mouse."} {"geneset":"GSE21927_SPLENIC_VS_TUMOR_MONOCYTES_FROM_C26GM_TUMOROUS_MICE_BALBC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLENIC_VS_TUMOR_MONOCYTES_FROM_C26GM_TUMOROUS_MICE_BALBC_UP","description":"Genes up-regulated in CD11b+ cells from BALB/c mice bearing C26GM colon carcinoma: spleen versus tumor."} {"geneset":"GSE21927_UNTREATED_VS_GMCSF_GCSF_TREATED_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_UNTREATED_VS_GMCSF_GCSF_TREATED_BONE_MARROW_UP","description":"Genes up-regulated in CD11b BoneMarrow from BALBc mouse versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and GCSF."} {"geneset":"GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_UP","description":"Genes up-regulated in CD11b+ cells from spleen of BALB/c mice bearing C26GM colon carcinoma versus CD11b+ cells from tumors of BALB/c mice bearing 4T1 mammary carcinoma."} {"geneset":"GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN","description":"Genes down-regulated in CD11b+ cells from spleen of BALB/c mice bearing C26GM colon carcinoma versus CD11b+ cells from tumors of BALB/c mice bearing 4T1 mammary carcinoma."} {"geneset":"GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_UP","description":"Genes up-regulated in CD11b+ cells from spleen of BALB/c mice bearing C26GM colon carcinoma versus CD11b+ cells from bone marrow of healthy BALB/c mice."} {"geneset":"GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_DN","description":"Genes down-regulated in CD11b+ cells from spleen of BALB/c mice bearing C26GM colon carcinoma versus CD11b+ cells from bone marrow of healthy BALB/c mice."} {"geneset":"GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_UP","description":"Genes up-regulated in CD11b+ cells from spleen of healthy C57BL6 mice versus CD11b+ cells from tumor infiltrating monocytes of BALB/c mice bearing 4T1 mammary carcinoma."} {"geneset":"GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_DN","description":"Genes down-regulated in CD11b+ cells from spleen of healthy C57BL6 mice versus CD11b+ cells from tumor infiltrating monocytes of BALB/c mice bearing 4T1 mammary carcinoma."} {"geneset":"GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP","description":"Genes up-regulated in CD11b+ from spleen of healthy C57BL6 versus CD11b+ cells from tumors of C57BL6 mice bearing EL4 lymphoma."} {"geneset":"GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_DN","description":"Genes down-regulated in CD11b+ from spleen of healthy C57BL6 versus CD11b+ cells from tumors of C57BL6 mice bearing EL4 lymphoma."} {"geneset":"GSE21927_SPLENIC_VS_TUMOR_MONOCYTES_FROM_C26GM_TUMOROUS_MICE_BALBC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_SPLENIC_VS_TUMOR_MONOCYTES_FROM_C26GM_TUMOROUS_MICE_BALBC_DN","description":"Genes down-regulated in CD11b+ cells from BALB/c mice bearing C26GM colon carcinoma: spleen versus tumor."} {"geneset":"GSE21927_BALBC_VS_C57BL6_MONOCYTE_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_BALBC_VS_C57BL6_MONOCYTE_TUMOR_UP","description":"Genes up-regulated in CD11b Tumor from BALBc mouse versus CD11b Tumor from C57BL6 mouse."} {"geneset":"GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN","description":"Genes down-regulated in CD11b+ cells from BALB/c mice bearing: C26GM colon carcinoma versus 4T1 mammary carcinoma."} {"geneset":"GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_DN","description":"Genes down-regulated in CD11b BoneMarrow from BALBc mouse incubated with GMCSF and IL-6 versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and GCSF."} {"geneset":"GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells: 1' versus 4'."} {"geneset":"GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells: 2' versus 3'."} {"geneset":"GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus 3' memory."} {"geneset":"GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated inCD8 T cells: naü¾™¦”¼ve versus 4' memory."} {"geneset":"GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus 3' memory."} {"geneset":"GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated inCD8 T cells: naü¾™¦”¼ve versus 4' memory."} {"geneset":"GSE21360_PRIMARY_VS_SECONDARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_PRIMARY_VS_SECONDARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in 1'Memory CD8T versus 2'Memory CD8T."} {"geneset":"GSE21360_PRIMARY_VS_SECONDARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_PRIMARY_VS_SECONDARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in 1'Memory CD8T versus 2'Memory CD8T."} {"geneset":"GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells: 2' versus 3'."} {"geneset":"GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells: 2' versus 4'."} {"geneset":"GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells: 1' versus 4'."} {"geneset":"GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus 1' memory."} {"geneset":"GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus 1' memory."} {"geneset":"GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus 2' memory."} {"geneset":"GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus 2' memory."} {"geneset":"GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells: 2' versus 4'."} {"geneset":"GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells: 3' versus 4'."} {"geneset":"GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells: 3' versus 4'."} {"geneset":"GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells: 1' versus 3'."} {"geneset":"GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells: 1' versus 3'."} {"geneset":"GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_DN","description":"Genes down-regulated in healthy CD4 [GeneID=920] T cells: germ free versus specific pathogen free."} {"geneset":"GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_DN","description":"Genes down-regulated in arthritic (KRN model) CD4 [GeneID=920] T cells: germ free versus specific pathogen free conditions."} {"geneset":"GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells under germ free conditions: healthy versus arthritis (KRN model)."} {"geneset":"GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells under germ free conditions: healthy versus arthritis (KRN model)."} {"geneset":"GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_UP","description":"Genes up-regulated in arthritic (KRN model) CD4 [GeneID=920] T cells: germ free versus specific pathogen free conditions."} {"geneset":"GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells under specific pathogen free conditions: healthy versus arthritis (KRN model)."} {"geneset":"GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells under specific pathogen free conditions: healthy versus arthritis (KRN model)."} {"geneset":"GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_UP","description":"Genes up-regulated in healthy CD4 [GeneID=920] T cells: germ free versus specific pathogen free."} {"geneset":"GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in skin gamma delta T cells: healthy versus obesity."} {"geneset":"GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in skin gamma delta T cells: healthy versus obesity."} {"geneset":"GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP","description":"Genes up-regulated in ex vivo follicular dendritic cells from peripheral lymph nodes: naü¾™¦”¼ve versus immunized mice."} {"geneset":"GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN","description":"Genes down-regulated in ex vivo follicular dendritic cells from peripheral lymph nodes: naü¾™¦”¼ve versus immunized mice."} {"geneset":"GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN","description":"Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes: non-stimulated versus tretinoin [PubChem=444795] and Pam2CSK4 (96h)."} {"geneset":"GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP","description":"Genes up-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes: non-stimulated versus tretinoin [PubChem=444795] (96h)."} {"geneset":"GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN","description":"Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes: non-stimulated versus tretinoin [PubChem=444795] (96h)."} {"geneset":"GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP","description":"Genes up-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes: non-stimulated versus tretinoin [PubChem=444795] and Pam2CSK4 (96h)."} {"geneset":"GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP","description":"Genes up-regulated in ex vivo follicular dendritic cells: peripheral lymph node versus Peyers patch."} {"geneset":"GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_DN","description":"Genes down-regulated in ex vivo follicular dendritic cells: peripheral lymph node versus Peyers patch."} {"geneset":"GSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN","description":"Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): Pam2CSK4 versus tretinoin [PubChem=444795] and Pam2CSK4."} {"geneset":"GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP","description":"Genes up-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes: unstimulated versus Pam2CSK4 (96h)."} {"geneset":"GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_DN","description":"Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes: unstimulated versus Pam2CSK4 (96h)."} {"geneset":"GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN","description":"Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): Pam2CSK4 versus tretinoin [PubChem=444795]."} {"geneset":"GSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP","description":"Genes up-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): Pam2CSK4 versus tretinoin [PubChem=444795] and Pam2CSK4."} {"geneset":"GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP","description":"Genes up-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): Pam2CSK4 versus tretinoin [PubChem=444795]."} {"geneset":"GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN","description":"Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): tretinoin [PubChem=444795] versus tretinoin [PubChem=444795] and Pam2CSK4."} {"geneset":"GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP","description":"Genes up-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): tretinoin [PubChem=444795] versus tretinoin [PubChem=444795] and Pam2CSK4."} {"geneset":"GSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_DN","description":"Genes down-regulated in ankle joints from SPHK1 [GeneID=8877] knockout: TNF [GeneID=7124] over-expression versus control."} {"geneset":"GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_UP","description":"Genes up-regulated in ankle joints: SPHK1 [GeneID=8877] versus wildtype over-expressing TNF [GeneID=7124]."} {"geneset":"GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_DN","description":"Genes down-regulated in ankle joints: SPHK1 [GeneID=8877] versus wildtype over-expressing TNF [GeneID=7124]."} {"geneset":"GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP","description":"Genes up-regulated in ankle joints over-expressing TNF [GeneID=7124]: SPHK1 [GeneID=8877] knockout versus wildtype."} {"geneset":"GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_DN","description":"Genes down-regulated in ankle joints over-expressing TNF [GeneID=7124]: SPHK1 [GeneID=8877] knockout versus wildtype."} {"geneset":"GSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_UP","description":"Genes up-regulated in ankle joints from SPHK1 [GeneID=8877] knockout: TNF [GeneID=7124] over-expression versus control."} {"geneset":"GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_UP","description":"Genes up-regulated in mouse embryonic fibroblasts (MEF): untreated versus MRL24 [PubChem=9958543]."} {"geneset":"GSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_DN","description":"Genes down-regulated in mouse embryonic fibroblasts (MEF): untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE22033_WT_VS_PPARG_KO_MEF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22033_WT_VS_PPARG_KO_MEF_DN","description":"Genes down-regulated in mouse embryonic fibroblasts (MEF): wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE22033_WT_VS_PPARG_KO_MEF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22033_WT_VS_PPARG_KO_MEF_UP","description":"Genes up-regulated in mouse embryonic fibroblasts (MEF): wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_UP","description":"Genes up-regulated in mouse embryonic fibroblasts (MEF): untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_DN","description":"Genes down-regulated in mouse embryonic fibroblasts (MEF): untreated versus MRL24 [PubChem=9958543]."} {"geneset":"GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: control versus tretinoin [PubChem=444795]."} {"geneset":"GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: control versus tretinoin [PubChem=444795]."} {"geneset":"GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: tretinoin [PubChem=444795] versus Ro 41-5253 [PubChem=5312120]."} {"geneset":"GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: control versus Ro 41-5253 [PubChem=5312120]."} {"geneset":"GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: control versus Ro 41-5253 [PubChem=5312120]."} {"geneset":"GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: tretinoin [PubChem=444795] versus Ro 41-5253 [PubChem=5312120]."} {"geneset":"GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_DN","description":"Genes down-regulated in T reg following anti-CD3 in vivo treatment versus control."} {"geneset":"GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_UP","description":"Genes up-regulated in T reg following anti-CD3 in vivo treatment versus control."} {"geneset":"GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_DN","description":"Genes down-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 3h."} {"geneset":"GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP","description":"Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 6h."} {"geneset":"GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_UP","description":"Genes up-regulated in bone marrow-derived dendritic 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up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 12h."} {"geneset":"GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_UP","description":"Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 12h."} {"geneset":"GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 24h."} {"geneset":"GSE21033_1H_VS_24H_POLYIC_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_1H_VS_24H_POLYIC_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 24h."} {"geneset":"GSE21033_3H_VS_12H_POLYIC_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_3H_VS_12H_POLYIC_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 3h versus 12h."} {"geneset":"GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_UP","description":"Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 24h."} {"geneset":"GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN","description":"Genes down-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 6h."} {"geneset":"GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_DN","description":"Genes down-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 24h."} {"geneset":"GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_UP","description":"Genes up-regulated in macrophages treated by corticosterone [PubChem=5839]: wildtype versus NR3C2 [GeneID=4306] knockout."} {"geneset":"GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: wildtype versus NR3C2 [GeneID=4306] knockout."} {"geneset":"GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus corticosterone [PubChem=5839]."} {"geneset":"GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: wildtype versus NR3C2 [GeneID=4306] knockout."} {"geneset":"GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN","description":"Genes down-regulated in macrophages with NR3C2 [GeneID=4306] knockout: untreated versus corticosterone [PubChem=5839]."} {"geneset":"GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus corticosterone [PubChem=5839]."} {"geneset":"GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_UP","description":"Genes up-regulated in macrophages with NR3C2 [GeneID=4306] knockout: untreated versus corticosterone [PubChem=5839]."} {"geneset":"GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_DN","description":"Genes down-regulated in macrophages treated by corticosterone [PubChem=5839]: wildtype versus NR3C2 [GeneID=4306] knockout."} {"geneset":"GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_UP","description":"Genes up-regulated in macrophages 24h after M. bovis BCG infection: wildtype versus MYD88 [GeneID=4615] knockout."} {"geneset":"GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus 24h after M. bovis BCG infection."} {"geneset":"GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_DN","description":"Genes down-regulated in macrophages 12h after M. bovis BCG infection: wildtype versus MYD88 [GeneID=4615] knockout."} {"geneset":"GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus 12h after M. bovis BCG infection."} {"geneset":"GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_DN","description":"Genes down-regulated in macrophages 24h after M. bovis BCG infection: wildtype versus MYD88 [GeneID=4615] knockout."} {"geneset":"GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus 24h after M. bovis BCG infection."} {"geneset":"GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages after M. bovis BCG infection: 24h versus 48h."} {"geneset":"GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with MYD88 [GeneID=4615] knockout after M. bovis BCG infection: 24h versus 48h."} {"geneset":"GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus 12h after M. bovis BCG infection."} {"geneset":"GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP","description":"Genes up-regulated macrophages with MYD88 [GeneID=4615] knockout: untreated versus 12h after M. bovis BCG infection."} {"geneset":"GSE22935_WT_VS_MYD88_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_WT_VS_MYD88_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: wildtype versus MYD88 [GeneID=4615] knockout."} {"geneset":"GSE22935_WT_VS_MYD88_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_WT_VS_MYD88_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: wildtype versus MYD88 [GeneID=4615] knockout."} {"geneset":"GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_UP","description":"Genes up-regulated in macrophages 12h after M. bovis BCG infection: wildtype versus MYD88 [GeneID=4615] knockout."} {"geneset":"GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP","description":"Genes up-regulated macrophages with MYD88 [GeneID=4615] knockout: untreated versus 48h after M. bovis BCG infection."} {"geneset":"GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_UP","description":"Genes up-regulated in macrophages 48h after M. bovis BCG infection: wildtype versus MYD88 [GeneID=4615] knockout."} {"geneset":"GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN","description":"Genes down-regulated in macrophages 48h after M. bovis BCG infection: wildtype versus MYD88 [GeneID=4615] knockout."} {"geneset":"GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN","description":"Genes down-regulated macrophages with MYD88 [GeneID=4615] knockout: untreated versus 24h after M. bovis BCG infection."} {"geneset":"GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with MYD88 [GeneID=4615] knockout after M. bovis BCG infection: 24h versus 48h."} {"geneset":"GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN","description":"Genes down-regulated macrophages with MYD88 [GeneID=4615] knockout: untreated versus 48h after M. bovis BCG infection."} {"geneset":"GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages after M. bovis BCG infection: 24h versus 48h."} {"geneset":"GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: untreated versus 48h after M. bovis BCG infection."} {"geneset":"GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: untreated versus 48h after M. bovis BCG infection."} {"geneset":"GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN","description":"Genes down-regulated macrophages with MYD88 [GeneID=4615] knockout: untreated versus 12h after M. bovis BCG infection."} {"geneset":"GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP","description":"Genes up-regulated macrophages with MYD88 [GeneID=4615] knockout: untreated versus 24h after M. bovis BCG infection."} {"geneset":"GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells: wildtype versus TCF7 [GeneID=6932] knockout."} {"geneset":"GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells: wildtype versus TCF7 [GeneID=6932] knockout."} {"geneset":"GSE23695_CD57_POS_VS_NEG_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23695_CD57_POS_VS_NEG_NK_CELL_UP","description":"Genes up-regulated in NK cells: B3GAT1+ [GeneID=27087] versus B3GAT1- [GeneID=27087]."} {"geneset":"GSE23695_CD57_POS_VS_NEG_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23695_CD57_POS_VS_NEG_NK_CELL_DN","description":"Genes down-regulated in NK cells: B3GAT1+ [GeneID=27087] versus B3GAT1- [GeneID=27087]."} {"geneset":"GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in neutrophils: untreated versus stimulated by CSF2 and IFNG [GeneID=1437;3458]."} {"geneset":"GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in neutrophils: untreated versus LPS."} {"geneset":"GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in neutrophils: LPS versus stimulated by CSF2 and IFNG [GeneID=1437;3458]."} {"geneset":"GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN","description":"Genes down-regulated in neutrophils: untreated versus stimulated by CSF2 and IFNG [GeneID=1437;3458]."} {"geneset":"GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in neutrophils: untreated versus LPS."} {"geneset":"GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP","description":"Genes up-regulated in neutrophils: LPS versus stimulated by CSF2 and IFNG [GeneID=1437;3458]."} {"geneset":"GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: control versus HIV and SIV infection."} {"geneset":"GSE22589_HEALTHY_VS_SIV_INFECTED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_HEALTHY_VS_SIV_INFECTED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: control versus SIV infection."} {"geneset":"GSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells infected by: SIV versus HIV and SIV."} {"geneset":"GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells infected by: HIV versus HIV and SIV."} {"geneset":"GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells infected by: HIV versus HIV and SIV."} {"geneset":"GSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells infected by: SIV versus HIV and SIV."} {"geneset":"GSE22589_HEALTHY_VS_HIV_INFECTED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_HEALTHY_VS_HIV_INFECTED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: control versus HIV infection."} {"geneset":"GSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: control versus HIV infection."} {"geneset":"GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_UP","description":"Genes up-regulated in monocyte-derived dendritic cells: control versus HIV and SIV infection."} {"geneset":"GSE22589_HEALTHY_VS_SIV_INFECTED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22589_HEALTHY_VS_SIV_INFECTED_DC_DN","description":"Genes down-regulated in monocyte-derived dendritic cells: control versus SIV infection."} {"geneset":"GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_UP","description":"Genes up-regulated in dendritic cells: common versus plasmacytoid."} {"geneset":"GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_DN","description":"Genes down-regulated in dendritic cells: common versus plasmacytoid."} {"geneset":"GSE22432_MULTIPOTENT_PROGENITOR_VS_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_MULTIPOTENT_PROGENITOR_VS_PDC_DN","description":"Genes down-regulated in dendritic 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{"geneset":"GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UP","description":"Genes up-regulated in amplified: multipotent progenitors versus common dendritic cell progenitors."} {"geneset":"GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_DN","description":"Genes down-regulated in amplified: multipotent progenitors versus common dendritic cell progenitors."} {"geneset":"GSE22432_CDC_VS_COMMON_DC_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_CDC_VS_COMMON_DC_PROGENITOR_DN","description":"Genes down-regulated in common dendritic cells versus those cultured and untreated."} {"geneset":"GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_UP","description":"Genes up-regulated in cultured common dendritic cell progenitors: untreated versus TGFB1 [GeneID=7040] for 4h."} {"geneset":"GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_DN","description":"Genes down-regulated in cultured common dendritic cell progenitors: untreated versus TGFB1 [GeneID=7040] for 4h."} {"geneset":"GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_DN","description":"Genes down-regulated in amplified multipotent progenitors versus cultured untreated common dendritic cell progenitors."} {"geneset":"GSE22432_CDC_VS_COMMON_DC_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_CDC_VS_COMMON_DC_PROGENITOR_UP","description":"Genes up-regulated in common dendritic cells versus those cultured and untreated."} {"geneset":"GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_UP","description":"Genes up-regulated in amplified multipotent progenitors versus cultured untreated common dendritic cell progenitors."} {"geneset":"GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_DN","description":"Genes down-regulated in dendritic cells: plasmacytoid versus cultured common progenitors treated by TGFB1 [GeneID=7040] for 4h."} {"geneset":"GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_UP","description":"Genes up-regulated in dendritic cells: plasmacytoid versus cultured common progenitors treated by TGFB1 [GeneID=7040] for 4h."} {"geneset":"GSE22919_RESTING_VS_IL2_IL12_IL15_STIM_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22919_RESTING_VS_IL2_IL12_IL15_STIM_NK_CELL_DN","description":"Genes down-regulated in NK cells: fresh versus stimulated with IL2 [GeneID=3558], IL-12 and IL15 [GeneID=3600]."} {"geneset":"GSE22919_RESTING_VS_IL2_IL12_IL15_STIM_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22919_RESTING_VS_IL2_IL12_IL15_STIM_NK_CELL_UP","description":"Genes up-regulated in NK cells: fresh versus stimulated with IL2 [GeneID=3558], IL-12 and IL15 [GeneID=3600]."} {"geneset":"GSE24210_RESTING_TREG_VS_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_RESTING_TREG_VS_TCONV_UP","description":"Genes up-regulated in resting T reg versus T conv cells."} {"geneset":"GSE24210_RESTING_TREG_VS_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_RESTING_TREG_VS_TCONV_DN","description":"Genes down-regulated in resting T reg versus T conv cells."} {"geneset":"GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP","description":"Genes up-regulated in T conv cells: control versus treated with IL35."} {"geneset":"GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_DN","description":"Genes down-regulated in T conv cells: control versus treated with IL35."} {"geneset":"GSE24210_IL35_TREATED_VS_RESTING_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_IL35_TREATED_VS_RESTING_TREG_DN","description":"Genes down-regulated in T conv cells treated with IL35 versus resting T reg cells."} {"geneset":"GSE24210_TCONV_VS_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_TCONV_VS_TREG_DN","description":"Genes down-regulated in control T conv versus resting T reg cells."} {"geneset":"GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_UP","description":"Genes up-regulated in T conv cells: IL35 treated versus untreated."} {"geneset":"GSE24210_IL35_TREATED_VS_RESTING_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_IL35_TREATED_VS_RESTING_TREG_UP","description":"Genes up-regulated in T conv cells treated with IL35 versus resting T reg cells."} {"geneset":"GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_DN","description":"Genes down-regulated in T conv cells: IL35 treated versus untreated."} {"geneset":"GSE24210_TCONV_VS_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24210_TCONV_VS_TREG_UP","description":"Genes up-regulated in control T conv versus resting T reg cells."} {"geneset":"GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated versus IL6 and TGFB1 [GeneID=3569;7040]."} {"geneset":"GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus IL1B, IL6 [GeneID=3553;3569] and IL-23."} {"geneset":"GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated versus IL1B, IL6 [GeneID=3553;3569] and IL-23."} {"geneset":"GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated versus IL1B and IL6 [GeneID=3553;3569]."} {"geneset":"GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with IL1B and IL6 [GeneID=3553;3569] versus those also treated with IL-23."} {"geneset":"GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with IL1B and IL6 [GeneID=3553;3569] versus those also treated with TGFB1 [GeneID=7040]."} {"geneset":"GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus IL1B and IL6 [GeneID=3553;3569]."} {"geneset":"GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: IL1B, IL6 [GeneID=3553;3569] and IL-23 versus IL1B, IL6 and TGFB1 [GeneID=3553;3569;7040]."} {"geneset":"GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: IL1B, IL6 [GeneID=3553;3569] and IL-23 versus IL1B, IL6 and TGFB1 [GeneID=3553;3569;7040]."} {"geneset":"GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus IL6 and TGFB1 [GeneID=3569;7040]."} {"geneset":"GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with IL1B and IL6 [GeneID=3553;3569] versus those also treated with IL-23."} {"geneset":"GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with IL1B and IL6 [GeneID=3553;3569] versus those also treated with TGFB1 [GeneID=7040]."} {"geneset":"GSE24492_LYVE_NEG_VS_POS_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24492_LYVE_NEG_VS_POS_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: LYVE1+ [GeneID=10894] versus LYVE1- [GeneID=10894]."} {"geneset":"GSE24492_LYVE_NEG_VS_POS_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24492_LYVE_NEG_VS_POS_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: LYVE1+ [GeneID=10894] versus LYVE1- [GeneID=10894]."} {"geneset":"GSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP","description":"Genes up-regulated in B cells: light versus dark zone."} {"geneset":"GSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN","description":"Genes down-regulated in B cells: light versus dark zone."} {"geneset":"GSE23925_DARK_ZONE_VS_NAIVE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23925_DARK_ZONE_VS_NAIVE_BCELL_UP","description":"Genes up-regulated in B cells: dark zone versus naü¾™¦”¼ve."} {"geneset":"GSE23925_DARK_ZONE_VS_NAIVE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23925_DARK_ZONE_VS_NAIVE_BCELL_DN","description":"Genes down-regulated in B cells: dark zone versus naü¾™¦”¼ve."} {"geneset":"GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_DN","description":"Genes down-regulated in B cells: light zone versus naü¾™¦”¼ve."} {"geneset":"GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_UP","description":"Genes up-regulated in B cells: light zone versus naü¾™¦”¼ve."} {"geneset":"GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in monocytes (12h) versus macrophages (12h) treated with rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): control versus IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): control versus IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus IL4 [GeneID=3565]."} {"geneset":"GSE16385_MONOCYTE_VS_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_MACROPHAGE_UP","description":"Genes up-regulated in monocytes versus macrophages."} {"geneset":"GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus IFNG and TNF [GeneID=3458;7124]."} {"geneset":"GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus IFNG and TNF [GeneID=3458;7124]."} {"geneset":"GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in monocytes (12h) versus macrophages (12h) treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in monocytes (12h) versus macrophages (12h) treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_MONOCYTE_VS_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_MACROPHAGE_DN","description":"Genes down-regulated in monocytes versus macrophages."} {"geneset":"GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in monocytes (12h) versus macrophages (12h) treated with IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in monocytes (12h) versus macrophages (12h) treated with IL4 [GeneID=3565]."} {"geneset":"GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in monocytes (12h) versus macrophages (12h) treated with IL4 [GeneID=3565]."} {"geneset":"GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in monocytes (12h) versus macrophages (12h) treated with rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP","description":"Genes up-regulated in wildtype bone marrow-derived macrophages: control versus treated with rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN","description":"Genes down-regulated in wildtype bone marrow-derived macrophages: control versus treated with rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP","description":"Genes up-regulated in wildtype bone marrow-derived macrophages: control versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DN","description":"Genes down-regulated in wildtype bone marrow-derived macrophages: control versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): control versus rosiglitazone [PubChem=77999] and IL4 [GeneID=3565]."} {"geneset":"GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): control versus rosiglitazone [PubChem=77999] and IL4 [GeneID=3565]."} {"geneset":"GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in monocytes (12h) versus macrophages (12h) treated with IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_DN","description":"Genes down-regulated in macrophages (6h): IL4 [GeneID=3565] versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_MONOCYTE_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in monocytes (12h) versus macrophages (12h) treated with IFNG and TNF [GeneID=3458;7124]."} {"geneset":"GSE16385_MONOCYTE_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_MONOCYTE_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in monocytes (12h) versus macrophages (12h) treated with IFNG and TNF [GeneID=3458;7124]."} {"geneset":"GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN","description":"Genes down-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_UP","description":"Genes up-regulated in wildtype bone marrow-derived macrophages: control versus treated with IL4 [GeneID=3565]."} {"geneset":"GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_DN","description":"Genes down-regulated in wildtype bone marrow-derived macrophages: control versus treated with IL4 [GeneID=3565]."} {"geneset":"GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN","description":"Genes down-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus rosiglitazone [PubChem=77999] and IL4 [GeneID=3565]."} {"geneset":"GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP","description":"Genes up-regulated in wildtype bone marrow-derived macrophages: control versus treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DN","description":"Genes down-regulated in wildtype bone marrow-derived macrophages: control versus treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_CTRL_VS_IL4_STIM_STAT6_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_IL4_STIM_STAT6_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout: control versus treated with IL4 [GeneID=3565]."} {"geneset":"GSE25088_CTRL_VS_IL4_STIM_STAT6_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_IL4_STIM_STAT6_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout: control versus treated with IL4 [GeneID=3565]."} {"geneset":"GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout: control versus treated with rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): control versus IFNG and TNF [GeneID=3458;7124]."} {"geneset":"GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): control versus IFNG and TNF [GeneID=3458;7124]."} {"geneset":"GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN","description":"Genes down-regulated in bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: wildtype versus PPARG [GeneID=5468]."} {"geneset":"GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_UP","description":"Genes up-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP","description":"Genes up-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus rosiglitazone [PubChem=77999] and IL4 [GeneID=3565]."} {"geneset":"GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP","description":"Genes up-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN","description":"Genes down-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP","description":"Genes up-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]."} {"geneset":"GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN","description":"Genes down-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]."} {"geneset":"GSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE25123_WT_VS_PPARG_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_WT_VS_PPARG_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_UP","description":"Genes up-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565]: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN","description":"Genes down-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565]: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): control versus IL4 [GeneID=3565]."} {"geneset":"GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): control versus IL4 [GeneID=3565]."} {"geneset":"GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP","description":"Genes up-regulated in wildtype bone marrow-derived macrophages treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN","description":"Genes down-regulated in wildtype bone marrow-derived macrophages treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP","description":"Genes up-regulated in wildtype bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]."} {"geneset":"GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN","description":"Genes down-regulated in wildtype bone 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{"geneset":"GSE25088_WT_VS_STAT6_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_WT_VS_STAT6_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: wildtype versus STAT6 [GeneID=6778] knockout."} {"geneset":"GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus IL4 [GeneID=3565]."} {"geneset":"GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus IL4 [GeneID=3565]."} {"geneset":"GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP","description":"Genes up-regulated in bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: wildtype versus PPARG [GeneID=5468]."} {"geneset":"GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP","description":"Genes up-regulated in wildtype bone marrow-derived macrophages treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN","description":"Genes down-regulated in wildtype bone marrow-derived macrophages treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP","description":"Genes up-regulated in wildtype bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]."} {"geneset":"GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN","description":"Genes down-regulated in wildtype bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]."} {"geneset":"GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): IFNG and TNF [GeneID=3458;7124] versus IL4 [GeneID=3565]."} {"geneset":"GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP","description":"Genes up-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]."} {"geneset":"GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN","description":"Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]."} {"geneset":"GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus IL4 [GeneID=3565]."} {"geneset":"GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout: control versus treated with rosiglitazone [PubChem=77999]."} {"geneset":"GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_UP","description":"Genes up-regulated in macrophages (6h): IL4 [GeneID=3565] versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN","description":"Genes down-regulated in bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: wildtype versus STAT6 [GeneID=6778] knockout."} {"geneset":"GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_UP","description":"Genes up-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]: wildtype versus STAT6 [GeneID=6778] knockout."} {"geneset":"GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_DN","description":"Genes down-regulated in bone 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[PubChem=77999]."} {"geneset":"GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN","description":"Genes down-regulated in wildtype bone marrow-derived macrophages: control versus treated with rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): IFNG and TNF [GeneID=3458;7124] versus IL4 [GeneID=3565]."} {"geneset":"GSE16385_IFNG_TNF_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IFNG_TNF_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): IFNG and TNF [GeneID=3458;7124] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_IFNG_TNF_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IFNG_TNF_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): IFNG and TNF [GeneID=3458;7124] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): IL4 [GeneID=3565] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): IL4 [GeneID=3565] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP","description":"Genes up-regulated in bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: wildtype versus STAT6 [GeneID=6778] knockout."} {"geneset":"GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP","description":"Genes up-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout: control versus treated with IL4[GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout: control versus treated with IL4[GeneID=3565] and rosiglitazone [PubChem=77999]."} {"geneset":"GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus IFNG and TNF [GeneID=3458;7124]."} {"geneset":"GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_UP","description":"Genes up-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus IL4 [GeneID=3565]."} {"geneset":"GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN","description":"Genes down-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus IL4 [GeneID=3565]."} {"geneset":"GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_UP","description":"Genes up-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565]: wildtype versus STAT6 [GeneID=6778] knockout."} {"geneset":"GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_DN","description":"Genes down-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565]: wildtype versus STAT6 [GeneID=6778] knockout."} {"geneset":"GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus IFNG and TNF [GeneID=3458;7124]."} {"geneset":"GSE25088_WT_VS_STAT6_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25088_WT_VS_STAT6_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: wildtype versus STAT6 [GeneID=6778] knockout."} {"geneset":"GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN","description":"Genes down-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells activated by anti-CD3 and anti-CD28 versus those stimulated by IFNA5 [GeneID=3442]."} {"geneset":"GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: control versus stimulated by IFNA2 [GeneID=3440]."} {"geneset":"GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells activated by anti-CD3 and anti-CD28 versus those stimulated by IFNA2 [GeneID=3440]."} {"geneset":"GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus CD8 T cells stimulated by IFNA5 [GeneID=3442] and activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus CD8 T cells stimulated by IFNA5 [GeneID=3442] and activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: control versus stimulated by IFNA2 [GeneID=3440]."} {"geneset":"GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: control versus stimulated by IFNA2 [GeneID=3440] and activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells activated by anti-CD3 and anti-CD28 versus those stimulated by IFNA2 [GeneID=3440]."} {"geneset":"GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells activated by anti-CD3 and anti-CD28 versus those stimulated by IFNA5 [GeneID=3442]."} {"geneset":"GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus those activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus those activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T lymphocytes: control versus activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T lymphocytes: control versus activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: control versus stimulated by IFNA5 [GeneID=3442] and activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: control versus stimulated by IFNA2 [GeneID=3440] and activated by anti-CD3 and anti-CD28."} {"geneset":"GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: control versus stimulated by IFNA5 [GeneID=3442] and activated by anti-CD3 and anti-CD28."} {"geneset":"GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP","description":"Genes up-regulated in T cells: control versus TX527 (hypocalemic analog of 25-hydroxyvitamin D3 [PubChem=1593])."} {"geneset":"GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN","description":"Genes down-regulated in T cells: control versus TX527 (hypocalemic analog of 25-hydroxyvitamin D3 [PubChem=1593])."} {"geneset":"GSE24292_WT_VS_PPARG_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24292_WT_VS_PPARG_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE24292_WT_VS_PPARG_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24292_WT_VS_PPARG_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE24726_WT_VS_E2_2_KO_PDC_DAY6_POST_DELETION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24726_WT_VS_E2_2_KO_PDC_DAY6_POST_DELETION_DN","description":"Genes down-regulated in plasmacytoid dendritic cells (6 days after knockout): wildtype versus TCF4 [GeneID=6925] knockout."} {"geneset":"GSE24726_WT_VS_E2_22_KO_PDC_DAY4_POST_DELETION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24726_WT_VS_E2_22_KO_PDC_DAY4_POST_DELETION_DN","description":"Genes down-regulated in plasmacytoid dendritic cells (4 days after knockout): wildtype versus TCF4 [GeneID=6925] knockout."} {"geneset":"GSE24726_WT_VS_E2_2_KO_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24726_WT_VS_E2_2_KO_PDC_UP","description":"Genes up-regulated in plasmacytoid dendritic cells: wildtype versus TCF4 [GeneID=6925] knockout."} {"geneset":"GSE24726_WT_VS_E2_2_KO_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24726_WT_VS_E2_2_KO_PDC_DN","description":"Genes down-regulated in plasmacytoid dendritic cells: wildtype versus TCF4 [GeneID=6925] knockout."} {"geneset":"GSE24726_WT_VS_E2_2_KO_PDC_DAY6_POST_DELETION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24726_WT_VS_E2_2_KO_PDC_DAY6_POST_DELETION_UP","description":"Genes up-regulated in plasmacytoid dendritic cells (6 days after knockout): wildtype versus TCF4 [GeneID=6925] knockout."} {"geneset":"GSE24726_WT_VS_E2_2_KO_PDC_DAY4_POST_DELETION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24726_WT_VS_E2_2_KO_PDC_DAY4_POST_DELETION_UP","description":"Genes up-regulated in plasmacytoid dendritic cells (4 days after knockout): wildtype versus TCF4 [GeneID=6925] knockout."} {"geneset":"GSE22282_HYPOXIA_VS_NORMOXIA_MYELOID_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22282_HYPOXIA_VS_NORMOXIA_MYELOID_DC_DN","description":"Genes down-regulated in myeloid dendritic cells: hypoxia versus normoxia."} {"geneset":"GSE22282_HYPOXIA_VS_NORMOXIA_MYELOID_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22282_HYPOXIA_VS_NORMOXIA_MYELOID_DC_UP","description":"Genes up-regulated in myeloid dendritic cells: hypoxia versus normoxia."} {"geneset":"GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN","description":"Genes down-regulated in thymic implants from fetal liver versus those from adult bone marrow."} {"geneset":"GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN","description":"Genes down-regulated in thymic implants from fetal versus those from adult bone marrow."} {"geneset":"GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP","description":"Genes up-regulated in thymic implants from fetal liver versus those from adult bone marrow."} {"geneset":"GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP","description":"Genes up-regulated in thymic implants from fetal versus those from adult bone marrow."} {"geneset":"GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_UP","description":"Genes up-regulated in thymic implants from fetal liver versus those from fetal bone marrow."} {"geneset":"GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN","description":"Genes down-regulated in thymic implants from fetal liver versus those from fetal bone marrow."} {"geneset":"GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_DN","description":"Genes down-regulated in lymph node CD4 [GeneID=920] T cells: scurfy (non-functional form of FOXP3 [GeneID=50943]) versus scurfy and IL2 [GeneID=3558] knockout."} {"geneset":"GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_UP","description":"Genes up-regulated in lymph node CD4 [GeneID=920] T cells: scurfy (non-functional form of FOXP3 [GeneID=50943]) versus scurfy and IL2 [GeneID=3558] knockout."} {"geneset":"GSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_DN","description":"Genes down-regulated in myeloid-derived suppressor cells with HDC [GeneID=3067] knockout: bone marrow versus colon tumor."} {"geneset":"GSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_UP","description":"Genes up-regulated in myeloid-derived suppressor cells with HDC [GeneID=3067] knockout: bone marrow versus colon tumor."} {"geneset":"GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP","description":"Genes up-regulated in myeloid-derived suppressor cells from colon tumors: wildtype versus HDC [GeneID=3067] knockout."} {"geneset":"GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_DN","description":"Genes down-regulated in myeloid-derived suppressor cells from colon tumors: wildtype versus HDC [GeneID=3067] knockout."} {"geneset":"GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP","description":"Genes up-regulated in myeloid-derived suppressor cells: bone marrow versus colon tumor."} {"geneset":"GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN","description":"Genes down-regulated in myeloid-derived suppressor cells: bone marrow versus colon tumor."} {"geneset":"GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN","description":"Genes down-regulated in myeloid-derived suppressor cells from bone marrow: wildtype versus HDC [GeneID=3067] knockout."} {"geneset":"GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_UP","description":"Genes up-regulated in myeloid-derived suppressor cells from bone marrow: wildtype versus HDC [GeneID=3067] knockout."} {"geneset":"GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_UP","description":"Genes up-regulated in spleen follicular B lymphocytes: wildtype versus IRF8 [GeneID=3394] knockout."} {"geneset":"GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_DN","description":"Genes down-regulated in spleen B lymphocytes with IRF8 [GeneID=3394] knockout: marginal zone versus follicular."} {"geneset":"GSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_DN","description":"Genes down-regulated in spleen marginal zone B lymphocytes: wildtype versus IRF8 [GeneID=3394] knockout."} {"geneset":"GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_DN","description":"Genes down-regulated in speen B lymphocytes: marginal zone versus follicular."} {"geneset":"GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_DN","description":"Genes down-regulated in spleen follicular B lymphocytes: wildtype versus IRF8 [GeneID=3394] knockout."} {"geneset":"GSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_UP","description":"Genes up-regulated in spleen marginal zone B lymphocytes: wildtype versus IRF8 [GeneID=3394] knockout."} {"geneset":"GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_UP","description":"Genes up-regulated in speen B lymphocytes: marginal zone versus follicular."} {"geneset":"GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_UP","description":"Genes up-regulated in spleen B lymphocytes with IRF8 [GeneID=3394] knockout: marginal zone versus follicular."} {"geneset":"GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN","description":"Genes down-regulated in NFKB1 and IL10 [GeneID=4790;3586] knockout macrophages stimulated by LPS versus those also stimulated by IL10 [GeneID=3586]."} {"geneset":"GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages stimulated by LPS: IL10 [GeneID=3586] knockout versus IL10 and NFKB1 [GeneID=3586;4790] knockout."} {"geneset":"GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP","description":"Genes up-regulated in unstimulated IL10 [GeneID=3586] knockout macrophages versus NFKB1 and IL10 [GeneID=4790;3586] knockout macrophages stimulated by LPS."} {"geneset":"GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_UP","description":"Genes up-regulated in IL10 [GeneID=3586] knockout macrophages: unstimulated versus LPS."} {"geneset":"GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_DN","description":"Genes down-regulated in IL10 [GeneID=3586] knockout macrophages: unstimulated versus LPS."} {"geneset":"GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP","description":"Genes up-regulated in IL10 [GeneID=3586] knockout macrophages: unstimulated versus stimulated by IL10 [GeneID=3586] and LPS."} {"geneset":"GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN","description":"Genes down-regulated in IL10 [GeneID=3586] knockout macrophages: unstimulated versus stimulated by IL10 [GeneID=3586] and LPS."} {"geneset":"GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_DN","description":"Genes down-regulated in unstimulated macrophages: IL10 [GeneID=3586] knockout versus NFKB1 [GeneID=4790] knockout."} {"geneset":"GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN","description":"Genes down-regulated in unstimulated IL10 [GeneID=3586] knockout macrophages versus NFKB1 and IL10 [GeneID=4790;3586] knockout macrophages stimulated by LPS."} {"geneset":"GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_UP","description":"Genes up-regulated in unstimulated macrophages: IL10 [GeneID=3586] knockout versus NFKB1 [GeneID=4790] knockout."} {"geneset":"GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN","description":"Genes down-regulated in IL10 and NFKB1 [GeneID=4790;3586] knockout macrophages: unstimulated versus stimulated by IL10 [GeneID=3586] and LPS."} {"geneset":"GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_UP","description":"Genes up-regulated in IL10 [GeneID=3586] knockout macrophages stimulated by IL10 [GeneID=3586] versus NFKB1 [GeneID=4790] knockout macrophages stimulated by IL10 [GeneID=3586] and LPS."} {"geneset":"GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages stimulated by LPS: IL10 [GeneID=3586] knockout versus IL10 and NFKB1 [GeneID=3586;4790] knockout."} {"geneset":"GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP","description":"Genes up-regulated in NFKB1 and IL10 [GeneID=4790;3586] knockout macrophages stimulated by LPS versus those also stimulated by IL10 [GeneID=3586]."} {"geneset":"GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP","description":"Genes up-regulated in IL10 and NFKB1 [GeneID=4790;3586] knockout macrophages: unstimulated versus stimulated by IL10 [GeneID=3586] and LPS."} {"geneset":"GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN","description":"Genes down-regulated in IL10 [GeneID=3586] knockout macrophages stimulated by IL10 [GeneID=3586] versus NFKB1 [GeneID=4790] knockout macrophages stimulated by IL10 [GeneID=3586] and LPS."} {"geneset":"GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN","description":"Genes down-regulated in IL10 [GeneID=3586] knockout macrophages stimulated by LPS versus those also stimulated by IL10 [GeneID=3586]."} {"geneset":"GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP","description":"Genes up-regulated in IL10 [GeneID=3586] knockout macrophages stimulated by LPS versus those also stimulated by IL10 [GeneID=3586]."} {"geneset":"GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP","description":"Genes up-regulated in AGS cells (gastric adenocarcinoma): control versus H. pylori LPS."} {"geneset":"GSE25147_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_MKN45_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25147_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_MKN45_CELL_DN","description":"Genes down-regulated in MKN45 cells (stomach cancer): control versus H. pylori LPS."} {"geneset":"GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN","description":"Genes down-regulated in AGS cells (gastric adenocarcinoma): control versus H. pylori LPS."} {"geneset":"GSE25147_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_MKN45_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25147_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_MKN45_CELL_UP","description":"Genes up-regulated in MKN45 cells (stomach cancer): control versus H. pylori LPS."} {"geneset":"GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_UP","description":"Genes up-regulated in decidual macrophages with ITGAX [GeneID=3687] high versus low."} {"geneset":"GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_DN","description":"Genes down-regulated in decidual macrophages with ITGAX [GeneID=3687] high versus low."} {"geneset":"GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN","description":"Genes down-regulated in cytotoxic T cells: control versus treated with Akt inhibitor VIII [PubChem=10196499]."} {"geneset":"GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP","description":"Genes up-regulated in cytotoxic T cells: wildtype versus PDK1 [GeneID=5163] knockout."} {"geneset":"GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP","description":"Genes up-regulated in cytotoxic T cells: control versus treated with Akt inhibitor VIII [PubChem=10196499]."} {"geneset":"GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN","description":"Genes down-regulated in cytotoxic T cells: wildtype versus PDK1 [GeneID=5163] knockout."} {"geneset":"GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_UP","description":"Genes up-regulated in CD8 T cells: IL10+ [GeneID=3586] versus IL10- [GeneID=3586]."} {"geneset":"GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_DN","description":"Genes down-regulated in CD8 T cells: IL10+ [GeneID=3586] versus IL10- [GeneID=3586]."} {"geneset":"GSE26023_PHD3_KO_VS_WT_NEUTROPHIL_HYPOXIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26023_PHD3_KO_VS_WT_NEUTROPHIL_HYPOXIA_DN","description":"Genes down-regulated in neutrophils under hypoxia: EGLN3 [GeneID=112399] knockout versus wildtype."} {"geneset":"GSE26023_PHD3_KO_VS_WT_NEUTROPHIL_HYPOXIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26023_PHD3_KO_VS_WT_NEUTROPHIL_HYPOXIA_UP","description":"Genes up-regulated in neutrophils under hypoxia: EGLN3 [GeneID=112399] knockout versus wildtype."} {"geneset":"GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_UP","description":"Genes up-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h."} {"geneset":"GSE22611_MUTANT_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_MUTANT_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_6H_DN","description":"Genes down-regulated in HEK293 cells at 6h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_UNSTIM_VS_2H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_UNSTIM_VS_2H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_UP","description":"Genes up-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 2h."} {"geneset":"GSE22611_UNSTIM_VS_2H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_UNSTIM_VS_2H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN","description":"Genes down-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 2h."} {"geneset":"GSE22611_MUTANT_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_MUTANT_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_6H_UP","description":"Genes up-regulated in HEK293 cells at 6h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP","description":"Genes up-regulated in HEK293 cells expressing mutant NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 2h."} {"geneset":"GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_UP","description":"Genes up-regulated in HEK293 cells at 6h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing wildtype NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_DN","description":"Genes down-regulated in HEK293 cells at 6h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing wildtype NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_UP","description":"Genes up-regulated in HEK293 cells at 2h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_UNSTIM_VS_6H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_UNSTIM_VS_6H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP","description":"Genes up-regulated in HEK293 cells expressing mutant NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h."} {"geneset":"GSE22611_UNSTIM_VS_6H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_UNSTIM_VS_6H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN","description":"Genes down-regulated in HEK293 cells expressing mutant NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h."} {"geneset":"GSE22611_NOD2_VS_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_VS_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP","description":"Genes up-regulated in HEK293 cells expressing: wildtype NOD2 [GeneID=64127] versus mutant NOD2 [GeneID=64127]."} {"geneset":"GSE22611_NOD2_VS_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_VS_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN","description":"Genes down-regulated in HEK293 cells expressing: wildtype NOD2 [GeneID=64127] versus mutant NOD2 [GeneID=64127]."} {"geneset":"GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP","description":"Genes up-regulated in HEK293 cells: over-expressing wildtype NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN","description":"Genes down-regulated in HEK293 cells: over-expressing wildtype NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP","description":"Genes up-regulated in HEK293 cells: expressing mutant NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN","description":"Genes down-regulated in HEK293 cells: expressing mutant NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN","description":"Genes down-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h."} {"geneset":"GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_DN","description":"Genes down-regulated in HEK293 cells at 2h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN","description":"Genes down-regulated in HEK293 cells expressing mutant NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 2h."} {"geneset":"GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP","description":"Genes up-regulated in HEK293 cells at 2h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing wildtype NOD2 [GeneID=64127] versus control."} {"geneset":"GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN","description":"Genes down-regulated in HEK293 cells at 2h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing wildtype NOD2 [GeneID=64127] versus control."} {"geneset":"GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_DN","description":"Genes down-regulated in B lymphocytes immunized with: monophosphoryl lipid A (MPL) versus MPL and imiquimod [PubChem=13982876]."} {"geneset":"GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN","description":"Genes down-regulated in B lymphocytes immunized with: imiquimod [PubChem=13982876] versus monophosphoryl lipid A and imiquimod [PubChem=13982876]."} {"geneset":"GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_UP","description":"Genes up-regulated in B lymphocytes immunized with: monophosphoryl lipid A (MPL) versus MPL and imiquimod [PubChem=13982876]."} {"geneset":"GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_UP","description":"Genes up-regulated in B lymphocytes immunized with: imiquimod [PubChem=13982876] versus monophosphoryl lipid A and imiquimod [PubChem=13982876]."} {"geneset":"GSE25677_MPL_VS_R848_STIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25677_MPL_VS_R848_STIM_BCELL_UP","description":"Genes up-regulated in B lymphocytes after immunization with: monophosphoryl lipid A versus imiquimod [PubChem=13982876]."} {"geneset":"GSE25677_MPL_VS_R848_STIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25677_MPL_VS_R848_STIM_BCELL_DN","description":"Genes down-regulated in B lymphocytes after immunization with: monophosphoryl lipid A versus imiquimod [PubChem=13982876]."} {"geneset":"GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes: wildtype versus over-expressing HDAC7[GeneID=51564] fused with VP16."} {"geneset":"GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes from OT-2 transgenic mice: control versus injected with agonist peptide."} {"geneset":"GSE26488_HDAC7_KO_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_HDAC7_KO_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes: HDAC7 [GeneID=51564] knockout versus over-expressing HDAC7 [GeneID=51564] fused with VP16."} {"geneset":"GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes from OT-2 transgenic mice: control versus injected with agonist peptide."} {"geneset":"GSE26488_WT_VS_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_WT_VS_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes: wildtype versus HDAC7 [GeneID=51563] knockout."} {"geneset":"GSE26488_WT_VS_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_WT_VS_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes: wildtype versus HDAC7 [GeneID=51563] knockout."} {"geneset":"GSE26488_HDAC7_KO_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_HDAC7_KO_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocytes: HDAC7 [GeneID=51564] knockout versus over-expressing HDAC7 [GeneID=51564] fused with VP16."} {"geneset":"GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN","description":"Genes down-regulated in dobule positive thymocytefrom OT-2 transgenic mice injected with agonist peptide: wildtype versus expressing deltaP form of HDAC7 [GeneID=51564]."} {"geneset":"GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_UP","description":"Genes up-regulated in dobule positive thymocytefrom OT-2 transgenic mice injected with agonist peptide: wildtype versus expressing deltaP form of HDAC7 [GeneID=51564]."} {"geneset":"GSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_DN","description":"Genes down-regulated in double positive thymocyte from OT-2 transgenic mice: control versus HDAC7 [GeneID=51564] deltaP form after injection with agonist peptide."} {"geneset":"GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocytes: wildtype versus over-expressing HDAC7[GeneID=51564] fused with VP16."} {"geneset":"GSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_UP","description":"Genes up-regulated in double positive thymocyte from OT-2 transgenic mice: control versus HDAC7 [GeneID=51564] deltaP form after injection with agonist peptide."} {"geneset":"GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_UP","description":"Genes up-regulated in wildtype cytotoxic T lymphocytes versus those overexpressing phosphorylation deficient form of HDAC7 [GeneID=51564]."} {"geneset":"GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_DN","description":"Genes down-regulated in wildtype cytotoxic T lymphocytes versus those overexpressing phosphorylation deficient form of HDAC7 [GeneID=51564]."} {"geneset":"GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: tumoricidal versus control."} {"geneset":"GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: tumoricidal versus control."} {"geneset":"GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_DN","description":"Genes down-regulated in germinal center B lymphocytes: control versus over-expressing PRDM1 [GeneID=639]."} {"geneset":"GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_UP","description":"Genes up-regulated in germinal center B lymphocytes over-expressing: PRDM1 [GeneID=639] versus Epstein-Barr virus protein LMP1."} {"geneset":"GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_DN","description":"Genes down-regulated in germinal center B lymphocytes over-expressing: PRDM1 [GeneID=639] versus Epstein-Barr virus protein LMP1."} {"geneset":"GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_UP","description":"Genes up-regulated in germinal center B lymphocytes: control versus over-expressing PRDM1 [GeneID=639]."} {"geneset":"GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_UP","description":"Genes up-regulated in germinal center B lymphocytes: control versus over-expressing Epstein-Barr virus protein LMP1."} {"geneset":"GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_DN","description":"Genes down-regulated in germinal center B lymphocytes: control versus over-expressing Epstein-Barr virus protein LMP1."} {"geneset":"GSE22443_IL2_VS_IL12_TREATED_ACT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22443_IL2_VS_IL12_TREATED_ACT_CD8_TCELL_DN","description":"Genes down-regulated in Pmel-1 CD8 T cells primed with cognate antigen: IL2 [GeneID=3558] versus IL-12."} {"geneset":"GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_DN","description":"Genes down-regulated in Pmel-1 CD8 T cells: naü¾™¦”¼ve versus primed with cognate antigen (gp100) and IL2 [GeneID=3558]."} {"geneset":"GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_UP","description":"Genes up-regulated in Pmel-1 CD8 T cells: naü¾™¦”¼ve versus primed with cognate antigen (gp100) and IL-12."} {"geneset":"GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_UP","description":"Genes up-regulated in Pmel-1 CD8 T cells: naü¾™¦”¼ve versus primed with cognate antigen (gp100) and IL2 [GeneID=3558]."} {"geneset":"GSE22443_IL2_VS_IL12_TREATED_ACT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22443_IL2_VS_IL12_TREATED_ACT_CD8_TCELL_UP","description":"Genes up-regulated in Pmel-1 CD8 T cells primed with cognate antigen: IL2 [GeneID=3558] versus IL-12."} {"geneset":"GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_DN","description":"Genes down-regulated in Pmel-1 CD8 T cells: naü¾™¦”¼ve versus primed with cognate antigen (gp100) and IL-12."} {"geneset":"GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP","description":"Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype untreated versus RORC [GeneID=6097] knockout treated by digoxin [PubChem=2724385]."} {"geneset":"GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN","description":"Genes down-regulated in polarizing CD4 [GeneID=920] Th17 cells: untreated versus digoxin [PubChem=2724385]."} {"geneset":"GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_DN","description":"Genes down-regulated in polarizing CD4 [GeneID=920] Th17 cells treated by digoxin [PubChem=2724385]: wildtype versus RORC [GeneID=6097] knockout."} {"geneset":"GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP","description":"Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype vs RORC [GeneID=6097] knockout treated with digoxin [PubChem=2724385]."} {"geneset":"GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP","description":"Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype versus RORC [GeneID=6097] knockout."} {"geneset":"GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN","description":"Genes down-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype untreated versus RORC [GeneID=6097] knockout treated by digoxin [PubChem=2724385]."} {"geneset":"GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP","description":"Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells treated by digoxin [PubChem=2724385]: wildtype versus RORC [GeneID=6097] knockout."} {"geneset":"GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN","description":"Genes down-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype vs RORC [GeneID=6097] knockout treated with digoxin [PubChem=2724385]."} {"geneset":"GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_DN","description":"Genes down-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype versus RORC [GeneID=6097] knockout."} {"geneset":"GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP","description":"Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells: untreated versus digoxin [PubChem=2724385]."} {"geneset":"GSE27896_HDAC6_KO_VS_WT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27896_HDAC6_KO_VS_WT_TREG_DN","description":"Genes down-regulated in T reg: HDAC6 [GeneID=10013] knockout versus wildtype."} {"geneset":"GSE27896_HDAC6_KO_VS_WT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27896_HDAC6_KO_VS_WT_TREG_UP","description":"Genes up-regulated in T reg: HDAC6 [GeneID=10013] knockout versus wildtype."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP","description":"Genes up-regulated in B lymphocytes: control versus stimulated by anti-IgM for 8h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_DN","description":"Genes down-regulated in B lymphocytes: control versus stimulated by anti-IgM for 3h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_UP","description":"Genes up-regulated in B lymphocytes: control versus stimulated by anti-IgM for 3h."} {"geneset":"GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_DN","description":"Genes down-regulated in B lymphocytes stimulated by anti-IgM for 16h: wildtype versus NFATC1 [GeneID=4772] knockout."} {"geneset":"GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_DN","description":"Genes down-regulated in B lymphocytes stimulated by anti-IgM for 3h: wildtype versus NFATC1 [GeneID=4772] knockout."} {"geneset":"GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_UP","description":"Genes up-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout stimulated by anti-IgM: 3h versus 16h."} {"geneset":"GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_DN","description":"Genes down-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout stimulated by anti-IgM: 3h versus 16h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP","description":"Genes up-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout: control versus stimulated by anti-IgM for 16h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_DN","description":"Genes down-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout: control versus stimulated by anti-IgM for 16h."} {"geneset":"GSE21063_WT_VS_NFATC1_KO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_WT_VS_NFATC1_KO_BCELL_UP","description":"Genes up-regulated in B lymphocytes: wildtype versus NFATC1 [GeneID=4772] knockout."} {"geneset":"GSE21063_WT_VS_NFATC1_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_WT_VS_NFATC1_KO_BCELL_DN","description":"Genes down-regulated in B lymphocytes: wildtype versus NFATC1 [GeneID=4772] knockout."} {"geneset":"GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_UP","description":"Genes up-regulated in B lymphocytes stimulated by anti-IgM for 3h: wildtype versus NFATC1 [GeneID=4772] knockout."} {"geneset":"GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_UP","description":"Genes up-regulated in B lymphocytes stimulated by anti-IgM: 3h versus 16h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_DN","description":"Genes down-regulated in B lymphocytes: control versus stimulated by anti-IgM for 8h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_UP","description":"Genes up-regulated in B lymphocytes: control versus stimulated by anti-IgM for 16h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_DN","description":"Genes down-regulated in B lymphocytes: control versus stimulated by anti-IgM for 16h."} {"geneset":"GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_UP","description":"Genes up-regulated in B lymphocytes stimulated by anti-IgM for 16h: wildtype versus NFATC1 [GeneID=4772] knockout."} {"geneset":"GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN","description":"Genes down-regulated in B lymphocytes stimulated by anti-IgM: 3h versus 16h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP","description":"Genes up-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout: control versus stimulated by anti-IgM for 8h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_DN","description":"Genes down-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout: control versus stimulated by anti-IgM for 8h."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_DN","description":"Genes down-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout: control versus stimulated by anti-IgM for 3h."} {"geneset":"GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP","description":"Genes up-regulated in B lymphocytes stimulated by anti-IgM for 8h: wildtype versus NFATC1 [GeneID=4772] knockout."} {"geneset":"GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_DN","description":"Genes down-regulated in B lymphocytes stimulated by anti-IgM for 8h: wildtype versus NFATC1 [GeneID=4772] knockout."} {"geneset":"GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_UP","description":"Genes up-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout: control versus stimulated by anti-IgM for 3h."} {"geneset":"GSE25502_WT_VS_KLF13_KO_THYMIC_MEMORY_LIKE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25502_WT_VS_KLF13_KO_THYMIC_MEMORY_LIKE_CD8_TCELL_UP","description":"Genes up-regulated in thymic memory like CD8 cells: wildtype versus KFL13 [GeneID=51621] knockout."} {"geneset":"GSE25502_WT_VS_KLF13_KO_THYMIC_MEMORY_LIKE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE25502_WT_VS_KLF13_KO_THYMIC_MEMORY_LIKE_CD8_TCELL_DN","description":"Genes down-regulated in thymic memory like CD8 cells: wildtype versus KFL13 [GeneID=51621] knockout."} {"geneset":"GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_UP","description":"Genes up-regulated in peritoneal cavity B lymphocytes: wildtype versus lupus susceptibility locus Sle2c1."} {"geneset":"GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_DN","description":"Genes down-regulated in peritoneal cavity B lymphocytes: wildtype versus lupus susceptibility locus Sle2c1."} {"geneset":"GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_UP","description":"Genes up-regulated in B lymphocytes from: peritoneal cavity versus spleen."} {"geneset":"GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_DN","description":"Genes down-regulated in lupus susceptibility locus Sle2c1 B lymphocytes from: peritoneal cavity versus spleen."} {"geneset":"GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_DN","description":"Genes down-regulated in spleen B lymphocytes: wildtype versus lupus susceptibility locus Sle2c1."} {"geneset":"GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP","description":"Genes up-regulated in spleen B lymphocytes: wildtype versus lupus susceptibility locus Sle2c1."} {"geneset":"GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_UP","description":"Genes up-regulated in lupus susceptibility locus Sle2c1 B lymphocytes from: peritoneal cavity versus spleen."} {"geneset":"GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_DN","description":"Genes down-regulated in B lymphocytes from: peritoneal cavity versus spleen."} {"geneset":"GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP","description":"Genes up-regulated in thymocytes: double positive versus CD4 [GeneID=920] single positive."} {"geneset":"GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN","description":"Genes down-regulated in thymocytes: double positive versus CD4 [GeneID=920] single positive."} {"geneset":"GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in peritoneal macrophages treated with LPS: wildtype versus KLF2 [GeneID=10365] knockout."} {"geneset":"GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in peritoneal macrophages treated with LPS: wildtype versus KLF2 [GeneID=10365] knockout."} {"geneset":"GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve T cells: CD4 [GeneID=920] versus Va24- NKT."} {"geneset":"GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_UP","description":"Genes up-regulated in activated T cells: CD4 [GeneID=920] versus Va24- NKT."} {"geneset":"GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN","description":"Genes down-regulated in activated T cells: CD4 [GeneID=920] versus Va24- NKT."} {"geneset":"GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve T cells: CD4 [GeneID=920] versus Va24- NKT."} {"geneset":"GSE28726_NAIVE_VS_ACTIVATED_VA24NEG_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_VS_ACTIVATED_VA24NEG_NKTCELL_DN","description":"Genes down-regulated in Va24- NKT cells: naü¾™¦”¼ve versus activated."} {"geneset":"GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve T cells: CD4 [GeneID=920] versus NK."} {"geneset":"GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve T cells: CD4 [GeneID=920] versus NK."} {"geneset":"GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_UP","description":"Genes up-regulated in activated T cells: CD4 [GeneID=920] versus NKT."} {"geneset":"GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN","description":"Genes down-regulated in activated T cells: CD4 [GeneID=920] versus NKT."} {"geneset":"GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: naü¾™¦”¼ve versus activated."} {"geneset":"GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_UP","description":"Genes up-regulated in NKT cells: naü¾™¦”¼ve versus activated."} {"geneset":"GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_DN","description":"Genes down-regulated in NKT cells: naü¾™¦”¼ve versus activated."} {"geneset":"GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: naü¾™¦”¼ve versus activated."} {"geneset":"GSE28726_NAIVE_VS_ACTIVATED_VA24NEG_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28726_NAIVE_VS_ACTIVATED_VA24NEG_NKTCELL_UP","description":"Genes up-regulated in Va24- NKT cells: naü¾™¦”¼ve versus activated."} {"geneset":"GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_UP","description":"Genes up-regulated in follicular helper T cells: BCL6 [GeneID=604] high versus BCL6 [GeneID=604] low."} {"geneset":"GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_DN","description":"Genes down-regulated in follicular helper T cells: BCL6 [GeneID=604] high versus BCL6 [GeneID=604] low."} {"geneset":"GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in BCL6 [GeneID=604] high follicular helper T cells versus naü¾™¦”¼ve T CD4 [GeneID=920] cells."} {"geneset":"GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in BCL6 [GeneID=604] high follicular helper T cells versus naü¾™¦”¼ve T CD4 [GeneID=920] cells."} {"geneset":"GSE24574_NAIVE_VS_TCONV_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_NAIVE_VS_TCONV_CD4_TCELL_UP","description":"Genes up-regulated in naü¾™¦”¼ve CD4 [GeneID=920] Tcells versus T conv cells."} {"geneset":"GSE24574_NAIVE_VS_TCONV_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_NAIVE_VS_TCONV_CD4_TCELL_DN","description":"Genes down-regulated in naü¾™¦”¼ve CD4 [GeneID=920] Tcells versus T conv cells."} {"geneset":"GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN","description":"Genes down-regulated in BCL6 [GeneID=604] high follicular helper T cells (Tfh) versus all Tfh."} {"geneset":"GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_DN","description":"Genes down-regulated in BCL6 [GeneID=604] low follicular helper T cells versus T conv cells."} {"geneset":"GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_DN","description":"Genes down-regulated in BCL6 [GeneID=604] high follicular helper T cells versus T conv cells."} {"geneset":"GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated in BCL6 [GeneID=604] low follicular helper T cells versus naü¾™¦”¼ve CD4 [GeneID=620] T cells."} {"geneset":"GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_UP","description":"Genes up-regulated in BCL6 [GeneID=604] high follicular helper T cells (Tfh) versus all Tfh."} {"geneset":"GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_UP","description":"Genes up-regulated in BCL6 [GeneID=604] high follicular helper T cells versus T conv cells."} {"geneset":"GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated in BCL6 [GeneID=604] low follicular helper T cells versus naü¾™¦”¼ve CD4 [GeneID=620] T cells."} {"geneset":"GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_UP","description":"Genes up-regulated in BCL6 [GeneID=604] low follicular helper T cells versus T conv cells."} {"geneset":"GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP","description":"Genes up-regulated in activated versus induced T reg cells."} {"geneset":"GSE28130_ACTIVATED_VS_INDUCEED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28130_ACTIVATED_VS_INDUCEED_TREG_DN","description":"Genes down-regulated in activated versus induced T reg cells."} {"geneset":"GSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_DN","description":"Genes down-regulated in germinal center B lymphocytes: wildtype versus ZBTB7A [GeneID=51341] knockout."} {"geneset":"GSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_UP","description":"Genes up-regulated in germinal center B lymphocytes: wildtype versus ZBTB7A [GeneID=51341] knockout."} {"geneset":"GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP","description":"Genes up-regulated in atherosclerosis macrophages: anti miR-33 versus untreated."} {"geneset":"GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN","description":"Genes down-regulated in atherosclerosis macrophages: anti miR-33 versus untreated."} {"geneset":"GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP","description":"Genes up-regulated in atherosclerosis macrophages: control anti miR ctrl versus untreated."} {"geneset":"GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_DN","description":"Genes down-regulated in atherosclerosis macrophages: anti miR-33 versus anti miR."} {"geneset":"GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN","description":"Genes down-regulated in atherosclerosis macrophages: control anti miR ctrl versus untreated."} {"geneset":"GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_UP","description":"Genes up-regulated in atherosclerosis macrophages: anti miR-33 versus anti miR."} {"geneset":"GSE19512_NAUTRAL_VS_INDUCED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19512_NAUTRAL_VS_INDUCED_TREG_DN","description":"Genes down-regulated in T reg: natural versus induced cells."} {"geneset":"GSE19512_NAUTRAL_VS_INDUCED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE19512_NAUTRAL_VS_INDUCED_TREG_UP","description":"Genes up-regulated in T reg: natural versus induced cells."} {"geneset":"GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN","description":"Genes down-regulated in T reg from: peripheral blood versus cord blood."} {"geneset":"GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP","description":"Genes up-regulated in T reg from: peripheral blood versus cord blood."} {"geneset":"GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated versus TGFB1 [GeneID=7040]."} {"geneset":"GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated versus progesterone [PubChem=5994]."} {"geneset":"GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: progesterone [PubChem=5994] versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]."} {"geneset":"GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: TGFB1 [GeneID=7040] versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]."} {"geneset":"GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: progesterone [PubChem=5994] versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]."} {"geneset":"GSE22025_UNTREATED_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_UNTREATED_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: untreated versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]."} {"geneset":"GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus progesterone [PubChem=5994]."} {"geneset":"GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus TGFB1 [GeneID=7040]."} {"geneset":"GSE22025_UNTREATED_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_UNTREATED_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]."} {"geneset":"GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: TGFB1 [GeneID=7040] versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]."} {"geneset":"GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_DN","description":"Genes down-regulated in brain microglia versus bone marrow monocytes."} {"geneset":"GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP","description":"Genes up-regulated in spleen dendritic cells: CD8- versus CD8+."} {"geneset":"GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_DN","description":"Genes down-regulated in spleen dendritic cells: CD8- versus CD8+."} {"geneset":"GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_UP","description":"Genes up-regulated in dendritic cells: spleen CD8- versus brain."} {"geneset":"GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP","description":"Genes up-regulated in brain microglia versus spleen CD8+ dendritic cells."} {"geneset":"GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_DN","description":"Genes down-regulated in brain microglia versus spleen CD8+ dendritic cells."} {"geneset":"GSE29949_MICROGLIA_VS_DC_BRAIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_MICROGLIA_VS_DC_BRAIN_UP","description":"Genes up-regulated in brain: microglia versus dendritic cells."} {"geneset":"GSE29949_MICROGLIA_BRAIN_VS_CD8_NEG_DC_SPLEEN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_MICROGLIA_BRAIN_VS_CD8_NEG_DC_SPLEEN_DN","description":"Genes down-regulated in brain microglia versus spleen CD8- dendritic cells."} {"geneset":"GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_UP","description":"Genes up-regulated in brain microglia versus bone marrow monocytes."} {"geneset":"GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN","description":"Genes down-regulated in dendritic cells: spleen CD8- versus brain."} {"geneset":"GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP","description":"Genes up-regulated in spleen CD8- dendritic cells versus bone marrow monocytes."} {"geneset":"GSE29949_MICROGLIA_VS_DC_BRAIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_MICROGLIA_VS_DC_BRAIN_DN","description":"Genes down-regulated in brain: microglia versus dendritic cells."} {"geneset":"GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_UP","description":"Genes up-regulated in dendritic cells: CD8+ spleen versus brain."} {"geneset":"GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_DN","description":"Genes down-regulated in dendritic cells: CD8+ spleen versus brain."} {"geneset":"GSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP","description":"Genes up-regulated in spleen CD8+ dendritic cells versus bone marrow monocytes."} {"geneset":"GSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN","description":"Genes down-regulated in spleen CD8+ dendritic cells versus bone marrow monocytes."} {"geneset":"GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP","description":"Genes up-regulated in brain dendritic 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{"geneset":"GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: stem cell memory versus effector memory."} {"geneset":"GSE23321_CENTRAL_MEMORY_VS_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23321_CENTRAL_MEMORY_VS_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: central memory versus naü¾™¦”¼ve."} {"geneset":"GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: central memory versus effector memory."} {"geneset":"GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in 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{"geneset":"GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: stem cell memory versus naü¾™¦”¼ve."} {"geneset":"GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: stem cell memory versus naü¾™¦”¼ve."} {"geneset":"GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: effector memory versus naü¾™¦”¼ve."} {"geneset":"GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_UP","description":"Genes up-regulated in 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{"geneset":"GSE27291_0H_VS_6H_STIM_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27291_0H_VS_6H_STIM_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in gamma delta T cells activated by phophoantigen BrHPP and IL2 [GeneID=3558]: 0h versus 6h."} {"geneset":"GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in gamma delta T cells activated by phophoantigen BrHPP and IL2 [GeneID=3558]: 0h versus 7 days."} {"geneset":"GSE27291_6H_VS_7D_STIM_GAMMADELTA_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27291_6H_VS_7D_STIM_GAMMADELTA_TCELL_UP","description":"Genes up-regulated in gamma delta T cells activated by phosphoantigen BrHPP and IL2 [GeneID=3558]: 6h versus 7 days."} {"geneset":"GSE27291_6H_VS_7D_STIM_GAMMADELTA_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27291_6H_VS_7D_STIM_GAMMADELTA_TCELL_DN","description":"Genes down-regulated in gamma delta T cells activated by phosphoantigen BrHPP and IL2 [GeneID=3558]: 6h versus 7 days."} {"geneset":"GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP","description":"Genes up-regulated in activated CD4 [GeneID=920] T cells: wildtype versus over-expressing MIR17 [GeneID=406952]."} {"geneset":"GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN","description":"Genes down-regulated in activated CD4 [GeneID=920] T cells: wildtype versus MIR17 [GeneID=406952] knockout."} {"geneset":"GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN","description":"Genes down-regulated in activated CD4 [GeneID=920] T cells: wildtype versus over-expressing MIR17 [GeneID=406952]."} {"geneset":"GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP","description":"Genes up-regulated in activated CD4 [GeneID=920] T cells with MIR17 [GeneID=406952] perturbation: knockout versus over-expression."} {"geneset":"GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_UP","description":"Genes up-regulated in activated CD4 [GeneID=920] T cells: wildtype versus MIR17 [GeneID=406952] knockout."} {"geneset":"GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN","description":"Genes down-regulated in activated CD4 [GeneID=920] T cells with MIR17 [GeneID=406952] perturbation: knockout versus over-expression."} {"geneset":"GSE31622_WT_VS_KLF3_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31622_WT_VS_KLF3_KO_BCELL_DN","description":"Genes down-regulated in splenic B lymphocytes: wildtype versus KLF3 [GeneID=51274] knockout."} {"geneset":"GSE31622_WT_VS_KLF3_KO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE31622_WT_VS_KLF3_KO_BCELL_UP","description":"Genes up-regulated in splenic B lymphocytes: wildtype versus KLF3 [GeneID=51274] knockout."} 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[PubChem=5287844] versus those stimulated by BMP4 [GeneID=652]."} {"geneset":"GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN","description":"Genes down-regulated in CD34+ [GeneID=947] cells: control versus stimulated by BMP4 [GeneID=652]."} {"geneset":"GSE26351_UNSTIM_VS_WNT_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26351_UNSTIM_VS_WNT_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP","description":"Genes up-regulated in CD34+ [GeneID=947] cells: control versus treated with GSK-3 Inhibitor IX (BIO) [PubChem=5287844]."} {"geneset":"GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP","description":"Genes up-regulated in CD34+ [GeneID=947] cells: control versus stimulated by BMP4 [GeneID=652]."} {"geneset":"GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP","description":"Genes up-regulated in B16 melanoma (day 3): untreated versus mock treatment during adoptive transfer therapy."} {"geneset":"GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN","description":"Genes down-regulated in B16 melanoma (day 3): untreated versus mock treatment during adoptive transfer therapy."} {"geneset":"GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN","description":"Genes down-regulated in B16 melanoma (day 3): untreated versus adoptive transfer therapy."} {"geneset":"GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_DN","description":"Genes down-regulated in untreated B16 melanoma: day 3 versus day 7."} {"geneset":"GSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_UP","description":"Genes up-regulated in mock treatment during adoptive transfer therapy of B16 melanoma: day 3 versus day 7."} {"geneset":"GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP","description":"Genes up-regulated in B16 melanoma (day 3): untreated versus adoptive transfer therapy."} {"geneset":"GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DN","description":"Genes down-regulated in B16 melanoma during adoptive transfer therapy: day 3 versus day 7."} {"geneset":"GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP","description":"Genes up-regulated in B16 melanoma at day 3 of adoptive transfer treatment: mock versus therapy."} {"geneset":"GSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_DN","description":"Genes down-regulated in mock treatment during adoptive transfer therapy of B16 melanoma: day 3 versus day 7."} {"geneset":"GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP","description":"Genes up-regulated in B16 melanoma during adoptive transfer therapy: day 3 versus day 7."} {"geneset":"GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_DN","description":"Genes down-regulated in B16 melanoma (day 7): untreated versus adoptive transfer therapy."} {"geneset":"GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP","description":"Genes up-regulated in B16 melanoma (day 7): untreated versus mock treatment during adoptive transfer therapy."} {"geneset":"GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN","description":"Genes down-regulated in B16 melanoma (day 7): untreated versus mock treatment during adoptive transfer therapy."} {"geneset":"GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP","description":"Genes up-regulated in B16 melanoma at day 7 of adoptive transfer treatment: mock versus therapy."} {"geneset":"GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN","description":"Genes down-regulated in B16 melanoma at day 7 of adoptive transfer treatment: mock versus therapy."} {"geneset":"GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_UP","description":"Genes up-regulated in untreated B16 melanoma: day 3 versus day 7."} {"geneset":"GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN","description":"Genes down-regulated in B16 melanoma at day 3 of adoptive transfer treatment: mock versus therapy."} {"geneset":"GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP","description":"Genes up-regulated in B16 melanoma (day 7): untreated versus adoptive transfer therapy."} {"geneset":"GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: over-expressing ID3 [GeneID=3399] versus ID3 [GeneID=3399] knockout."} {"geneset":"GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: control versus over-expressing ID3 [GeneID=3399]."} {"geneset":"GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: control versus over-expressing ID3 [GeneID=3399]."} {"geneset":"GSE23568_ID3_KO_VS_WT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23568_ID3_KO_VS_WT_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: ID3 [GeneID=3399] knockout versus wildtype."} {"geneset":"GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: over-expressing ID3 [GeneID=3399] versus ID3 [GeneID=3399] knockout."} {"geneset":"GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: ID3 [GeneID=3399] knockout versus wildtype."} {"geneset":"GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_DN","description":"Genes down-regulated CD8 T cells: mock transduced versus wildtype."} {"geneset":"GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP","description":"Genes up-regulated CD8 T cells: mock transduced versus wildtype."} {"geneset":"GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: resting differentiated versus alternatively activated M2."} {"geneset":"GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: resting differentiated versus alternatively activated M2."} {"geneset":"GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: alternatively activated M2 versus MYC [GeneID=4609] inhibited."} {"geneset":"GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: alternatively activated M2 versus MYC [GeneID=4609] inhibited."} {"geneset":"GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: resting differentiated versus MYC [GeneID=4609] inhibited."} {"geneset":"GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: resting differentiated versus MYC [GeneID=4609] inhibited."} {"geneset":"GSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN","description":"Genes down-regulated in KLRB1 high [GeneID=3820] T cells: CD8A [GeneID=925] versus CD8A CD8B [GeneID=925;926]."} {"geneset":"GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1 int [GeneID=3820]."} {"geneset":"GSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP","description":"Genes up-regulated in KLRB1 high [GeneID=3820] T cells: CD8A [GeneID=925] versus CD8A CD8B [GeneID=925;926]."} {"geneset":"GSE33425_CD161_INT_VS_NEG_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33425_CD161_INT_VS_NEG_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: KLRB1 int [GeneID=3820] versus KLRB1- [GeneID=3820]."} {"geneset":"GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1 int [GeneID=3820]."} {"geneset":"GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1- [GeneID=3820]."} {"geneset":"GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1- [GeneID=3820]."} {"geneset":"GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: KLRB1 int [GeneID=3820] versus KLRB1- [GeneID=3820]."} {"geneset":"GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1 int [GeneID=3820]."} {"geneset":"GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP","description":"Genes up-regulated in KLRB1 high [GeneID=3820] T cells: CD8A [GeneID=925] versus CD8A CD8B [GeneID=925;926]."} {"geneset":"GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN","description":"Genes down-regulated in KLRB1 high [GeneID=3820] T cells: CD8A [GeneID=925] versus CD8A CD8B [GeneID=925;926]."} {"geneset":"GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1 int [GeneID=3820]."} {"geneset":"GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1- [GeneID=3820]."} {"geneset":"GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1- [GeneID=3820]."} {"geneset":"GSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: KLRB1 int [GeneID=3820] versus KLRB1- [GeneID=3820]."} {"geneset":"GSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: KLRB1 int [GeneID=3820] versus KLRB1- [GeneID=3820]."} {"geneset":"GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in effector CD8 T cells: CXCR1+ [GeneID=3577] versus CXCR1- [GeneID=3577]."} {"geneset":"GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in effector CD8 T cells: CXCR1+ [GeneID=3577] versus CXCR1- [GeneID=3577]."} {"geneset":"GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_DN","description":"Genes down-regulated in T helper cells 5 days post polarization: Th1 versus Th17."} {"geneset":"GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_UP","description":"Genes up-regulated in T helper cells 15 days post polarization: Th1 versus Th17."} {"geneset":"GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP","description":"Genes up-regulated in T helper cells 5 days post polarization: Th1 versus Th17."} {"geneset":"GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP","description":"Genes up-regulated in Th1 cells 5 days post polarization: control versus stimulated with anti-CD3 and anti-CD28."} {"geneset":"GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_DN","description":"Genes down-regulated in Th1 cells 5 days post polarization: control versus stimulated with anti-CD3 and anti-CD28."} {"geneset":"GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP","description":"Genes up-regulated in Th1 cells 15 days post polarization: control versus stimulated with anti-CD3 and anti-CD28."} {"geneset":"GSE26030_TH1_VS_TH17_RESTIMULATED_DAY15_POST_POLARIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_TH1_VS_TH17_RESTIMULATED_DAY15_POST_POLARIZATION_DN","description":"Genes down-regulated in T helper cells 15 days post polarization and stimulated with anti-CD3 and anti-CD28: Th1 versus Th17."} {"geneset":"GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_DN","description":"Genes down-regulated in Th17 cells 15 days post polarization: control versus stimulated with anti-CD3 and anti-CD28."} {"geneset":"GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_UP","description":"Genes up-regulated in T helper cells 5 days post polarization and stimulated with anti-CD3 and anti-CD28: Th1 versus Th17."} {"geneset":"GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_DN","description":"Genes down-regulated in T helper cells 5 days post polarization and stimulated with anti-CD3 and anti-CD28: Th1 versus Th17."} {"geneset":"GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN","description":"Genes down-regulated in T helper cells 15 days post polarization: Th1 versus Th17."} {"geneset":"GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_DN","description":"Genes down-regulated in Th1 cells 15 days post polarization: control versus stimulated with anti-CD3 and anti-CD28."} {"geneset":"GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_UP","description":"Genes up-regulated in Th17 cells 15 days post polarization: control versus stimulated with anti-CD3 and anti-CD28."} {"geneset":"GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP","description":"Genes up-regulated in Th17 cells 5 days post polarization: control versus stimulated with anti-CD3 and anti-CD28."} {"geneset":"GSE26030_TH1_VS_TH17_RESTIMULATED_DAY15_POST_POLARIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_TH1_VS_TH17_RESTIMULATED_DAY15_POST_POLARIZATION_UP","description":"Genes up-regulated in T helper cells 15 days post polarization and stimulated with anti-CD3 and anti-CD28: Th1 versus Th17."} {"geneset":"GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN","description":"Genes down-regulated in Th17 cells 5 days post polarization: control versus stimulated with anti-CD3 and anti-CD28."} {"geneset":"GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: healthy versus systemic lupus erythematosus (SLE)."} {"geneset":"GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: healthy versus systemic lupus erythematosus (SLE)."} {"geneset":"GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_DN","description":"Genes down-regulated in macrophages versus dendritic cells sorted as ITGAX int [GeneID=3687] and EMR1 int [GeneID=2015]."} {"geneset":"GSE27859_MACROPHAGE_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_MACROPHAGE_VS_DC_DN","description":"Genes down-regulated in macrophages versus dendritic cells."} {"geneset":"GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_DN","description":"Genes down-regulated in macrophages versus those sorted as ITGAX int [GeneID=3687] and EMR1 high [GeneID=2015]."} {"geneset":"GSE27859_MACROPHAGE_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_MACROPHAGE_VS_DC_UP","description":"Genes up-regulated in macrophages versus dendritic cells."} {"geneset":"GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_UP","description":"Genes up-regulated in cells sorted as ITGAX int [GeneID=3687]: EMR1 high [GeneID=2015] macrophages versus EMR1 int [GeneID=2015] dendritic cells."} {"geneset":"GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_UP","description":"Genes up-regulated in macrophages versus those sorted as ITGAX int [GeneID=3687] and EMR1 high [GeneID=2015]."} {"geneset":"GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP","description":"Genes up-regulated in macrophages versus dendritic cells sorted as ITGAX int [GeneID=3687] and EMR1 int [GeneID=2015]."} {"geneset":"GSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_DN","description":"Genes down-regulated in dendritic cells versus macrophages sorted as ITGAX int [GeneID=3687] and EMR1 high [GeneID=2015]."} {"geneset":"GSE27859_DC_VS_CD11C_INT_F480_INT_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_DC_VS_CD11C_INT_F480_INT_DC_UP","description":"Genes up-regulated in dendritic cells versus those sorted as ITGAX int [GeneID=3687] and EMR1 int [GeneID=2015]."} {"geneset":"GSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_UP","description":"Genes up-regulated in dendritic cells versus macrophages sorted as ITGAX int [GeneID=3687] and EMR1 high [GeneID=2015]."} {"geneset":"GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_DN","description":"Genes down-regulated in cells sorted as ITGAX int [GeneID=3687]: EMR1 high [GeneID=2015] macrophages versus EMR1 int [GeneID=2015] dendritic cells."} {"geneset":"GSE27859_DC_VS_CD11C_INT_F480_INT_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27859_DC_VS_CD11C_INT_F480_INT_DC_DN","description":"Genes down-regulated in dendritic cells versus those sorted as ITGAX int [GeneID=3687] and EMR1 int [GeneID=2015]."} {"geneset":"GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_DN","description":"Genes down-regulated in T cell activation mechanism that was NOS2 [GeneID=4843] dependent versus NOS2 [GeneID=4843] independent activation."} {"geneset":"GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_UP","description":"Genes up-regulated in T cell activation mechanism that was NOS2 [GeneID=4843] dependent versus NOS2 [GeneID=4843] independent activation."} {"geneset":"GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_UNSTIM_VS_GMCSF_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_GMCSF_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437]."} {"geneset":"GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells CSF2 [GeneID=1437] versus CSF2 [GeneID=1437] and low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells CSF2 [GeneID=1437] versus CSF2 [GeneID=1437] and low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells: unstimulated versus low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells: unstimulated versus high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells: unstimulated versus high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437] and low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437] and low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells treated by CSF2 [GeneID=1437] and 1,3-beta-D-oligoglucan [PubChem=11375554]: low dose versus high dose."} {"geneset":"GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells CSF2 [GeneID=1437] versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells: low dose of 1,3-beta-D-oligoglucan [PubChem=11375554] versus CSF2 [GeneID=1437] and low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells: low dose of 1,3-beta-D-oligoglucan [PubChem=11375554] versus CSF2 [GeneID=1437] and low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells CSF2 [GeneID=1437] versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells: high dose of 1,3-beta-D-oligoglucan [PubChem=11375554] versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells treated with 1,3-beta-D-oligoglucan [PubChem=11375554]: low dose versus high dose."} {"geneset":"GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells treated with 1,3-beta-D-oligoglucan [PubChem=11375554]: low dose versus high dose."} {"geneset":"GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells: high dose of 1,3-beta-D-oligoglucan [PubChem=11375554] versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells: unstimulated versus low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]."} {"geneset":"GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP","description":"Genes up-regulated in bone marrow-derived dendritic cells treated by CSF2 [GeneID=1437] and 1,3-beta-D-oligoglucan [PubChem=11375554]: low dose versus high dose."} {"geneset":"GSE32986_UNSTIM_VS_GMCSF_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32986_UNSTIM_VS_GMCSF_STIM_DC_DN","description":"Genes down-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437]."} {"geneset":"GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_UP","description":"Genes up-regulated in bone marrow-derived macrophages stimulated with LPS: wildtype versus NFAT5 [GeneID=10725] knockout."} {"geneset":"GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages with NFAT5 [GeneID=10725] knockout: control versus stimulated with LPS."} {"geneset":"GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: wildtype versus NFAT5 [GeneID=10725] knockout."} {"geneset":"GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: wildtype versus NFAT5 [GeneID=10725] knockout."} {"geneset":"GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: control versus stimulated with LPS."} {"geneset":"GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages with NFAT5 [GeneID=10725] knockout: control versus stimulated with LPS."} {"geneset":"GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: control versus stimulated with LPS."} {"geneset":"GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN","description":"Genes down-regulated in bone marrow-derived macrophages stimulated with LPS: wildtype versus NFAT5 [GeneID=10725] knockout."} {"geneset":"GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in P14 CD8+ T cells: ST2 [GeneID=6761] knockout versus wildtype."} {"geneset":"GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in P14 CD8+ T cells: ST2 [GeneID=6761] knockout versus wildtype."} {"geneset":"GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: interferon alpha versus IFNG [GeneID=3458]."} {"geneset":"GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: untreated versus stimulated by IFNG [GeneID=3458]."} {"geneset":"GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: untreated versus stimulated by interferon alpha."} {"geneset":"GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: untreated versus stimulated by interferon alpha."} {"geneset":"GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_DN","description":"Genes down-regulated in bone marrow-derived macrophages: untreated versus stimulated by IFNG [GeneID=3458]."} {"geneset":"GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP","description":"Genes up-regulated in bone marrow-derived macrophages: interferon alpha versus IFNG [GeneID=3458]."} {"geneset":"GSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN","description":"Genes down-regulated in monocytes (6h): untreated versus muramyl dipeptide [PubChem=11620162] andM. tuberculosis 19 kDa lipopeptide."} {"geneset":"GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_UP","description":"Genes up-regulated in monocytes (6h): untreated versus muramyl dipeptide [PubChem=11620162]."} {"geneset":"GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_DN","description":"Genes down-regulated in monocytes (6h): untreated versus muramyl dipeptide [PubChem=11620162]."} {"geneset":"GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN","description":"Genes down-regulated in monocytes (6h): untreated versus M. tuberculosis 19 kDa lipopeptide."} {"geneset":"GSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP","description":"Genes up-regulated in monocytes (6h): untreated versus muramyl dipeptide [PubChem=11620162] andM. tuberculosis 19 kDa lipopeptide."} {"geneset":"GSE34156_UNTREATED_VS_24H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34156_UNTREATED_VS_24H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN","description":"Genes down-regulated in monocytes (24h): untreated versus muramyl dipeptide [PubChem=11620162] andM. tuberculosis 19 kDa lipopeptide."} {"geneset":"GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP","description":"Genes up-regulated in monocytes (24h): muramyl dipeptide 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{"geneset":"GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN","description":"Genes down-regulated in T cells stimulated by IL2 [GeneID=3558] for 2h: STAT5 double knock-in versus wildtype."} {"geneset":"GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_2H_UP","description":"Genes up-regulated in T cells: control versus IL2 [GeneID=3558] stimulation for 2h."} {"geneset":"GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_DN","description":"Genes down-regulated in T cells stimulated by IL2 [GeneID=3558] for 17h: STAT5 double knock-in versus wildtype."} {"geneset":"GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_DN","description":"Genes down-regulated in STAT5 double knock-in T cells: control versus IL2 [GeneID=3558] stimulation for 2h."} {"geneset":"GSE34515_CD16_NEG_MONOCYTE_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34515_CD16_NEG_MONOCYTE_VS_DC_UP","description":"Genes up-regulated in CD16- monocytes versus dendritic cells."} {"geneset":"GSE34515_CD16_NEG_VS_POS_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34515_CD16_NEG_VS_POS_MONOCYTE_DN","description":"Genes down-regulated in monocytes: CD16- versus CD16+."} {"geneset":"GSE34515_CD16_POS_MONOCYTE_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34515_CD16_POS_MONOCYTE_VS_DC_DN","description":"Genes down-regulated in CD16+ monocytes versus dendritic cells."} {"geneset":"GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP","description":"Genes up-regulated in monocytes: CD16- versus CD16+."} {"geneset":"GSE34515_CD16_POS_MONOCYTE_VS_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34515_CD16_POS_MONOCYTE_VS_DC_UP","description":"Genes up-regulated in CD16+ monocytes versus dendritic cells."} {"geneset":"GSE34515_CD16_NEG_MONOCYTE_VS_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34515_CD16_NEG_MONOCYTE_VS_DC_DN","description":"Genes down-regulated in CD16- monocytes versus dendritic cells."} {"geneset":"GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_UP","description":"Genes up-regulated in dendritic cells with knockout of NLRP10 [GeneID=338322]: control versus LPS."} {"geneset":"GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_DN","description":"Genes down-regulated in dendritic cells with knockout of NLRP10 [GeneID=338322]: control versus LPS."} {"geneset":"GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_UP","description":"Genes up-regulated in dendritic cells in response to LPS: wildtype versus NLRP10 [GeneID=338322] knockout."} {"geneset":"GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_DN","description":"Genes down-regulated in dendritic cells in response to LPS: wildtype versus NLRP10 [GeneID=338322] knockout."} {"geneset":"GSE36009_UNSTIM_VS_LPS_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36009_UNSTIM_VS_LPS_STIM_DC_DN","description":"Genes down-regulated in dendritic cells: control versus LPS."} {"geneset":"GSE36009_WT_VS_NLRP10_KO_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36009_WT_VS_NLRP10_KO_DC_UP","description":"Genes up-regulated in dendritic cells: wildtype versus NLRP10 [GeneID=338322] knockout."} {"geneset":"GSE36009_WT_VS_NLRP10_KO_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36009_WT_VS_NLRP10_KO_DC_DN","description":"Genes down-regulated in dendritic cells: wildtype versus NLRP10 [GeneID=338322] knockout."} {"geneset":"GSE36009_UNSTIM_VS_LPS_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36009_UNSTIM_VS_LPS_STIM_DC_UP","description":"Genes up-regulated in dendritic cells: control versus LPS."} {"geneset":"GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN","description":"Genes down-regulated in peritoneal macrophages: untreated versus poly(IC)."} {"geneset":"GSE36891_UNSTIM_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36891_UNSTIM_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP","description":"Genes up-regulated in peritoneal macrophages: control versus Pam3Cys-Ser-(Lys)4 [PubChem=130704]."} {"geneset":"GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_DN","description":"Genes down-regulated in peritoneal macrophages: poly(IC) versus Pam3Cys-Ser-(Lys)4 [PubChem=130704]."} {"geneset":"GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_UP","description":"Genes up-regulated in peritoneal macrophages: untreated versus poly(IC)."} {"geneset":"GSE36891_UNSTIM_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36891_UNSTIM_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_DN","description":"Genes down-regulated in peritoneal macrophages: control versus Pam3Cys-Ser-(Lys)4 [PubChem=130704]."} {"geneset":"GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP","description":"Genes up-regulated in peritoneal macrophages: poly(IC) versus Pam3Cys-Ser-(Lys)4 [PubChem=130704]."} {"geneset":"GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN","description":"Genes down-regulated in T reg (FOXP3+ [GeneID=50943]) cells from B6 mice: Foxp3-Fusion-GFP versus Foxp3-ires-GFP."} {"geneset":"GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_UP","description":"Genes up-regulated in splenocytes from Foxp3-ires-GFP B6 mice: T reg (FOXP3+ [GeneID=50943]) versus T conv (FOXP3- [GeneID=50943])."} {"geneset":"GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP","description":"Genes up-regulated in T reg (FOXP3+ [GeneID=50943]) cells from B6 mice: Foxp3-Fusion-GFP versus Foxp3-ires-GFP."} {"geneset":"GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_UP","description":"Genes up-regulated in splenocytes from Foxp3-Fusion-GFP B6 mice: T reg (FOXP3+ [GeneID=50943]) versus T conv (FOXP3- [GeneID=50943]) cells."} {"geneset":"GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_DN","description":"Genes down-regulated in splenocytes from Foxp3-Fusion-GFP B6 mice: T reg (FOXP3+ [GeneID=50943]) versus T conv (FOXP3- [GeneID=50943]) cells."} {"geneset":"GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP","description":"Genes up-regulated in splenocytes from Foxp3-Fusion-GFP NOD mice: T reg (FOXP3+ [GeneID=50943]) versus T conv (FOXP3- [GeneID=50943]) cells."} {"geneset":"GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_DN","description":"Genes down-regulated in splenocytes from Foxp3-Fusion-GFP NOD mice: T reg (FOXP3+ [GeneID=50943]) versus T conv (FOXP3- [GeneID=50943]) cells."} {"geneset":"GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_UP","description":"Genes up-regulated in Foxp3-Fusion-GFP T reg (FOXP3+ [GeneID=50943]): B6 versus NOD background."} {"geneset":"GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN","description":"Genes down-regulated in Foxp3-Fusion-GFP T reg (FOXP3+ [GeneID=50943]): B6 versus NOD background."} {"geneset":"GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_UP","description":"Genes up-regulated in Foxp3-ires-GFP T reg (FOXP3+ [GeneID=50943]): B6 versus NOD background."} {"geneset":"GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_DN","description":"Genes down-regulated in Foxp3-ires-GFP T reg (FOXP3+ [GeneID=50943]): B6 versus NOD background."} {"geneset":"GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_UP","description":"Genes up-regulated in T reg (FOXP3+ [GeneID=50943]) cells from NOD mice: Foxp3-Fusion-GFP versus Foxp3-ires-GFP."} {"geneset":"GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_DN","description":"Genes down-regulated in splenocytes from Foxp3-ires-GFP B6 mice: T reg (FOXP3+ [GeneID=50943]) versus T conv (FOXP3- [GeneID=50943])."} {"geneset":"GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP","description":"Genes up-regulated in FoxP3-IRES-GFP: NOD T reg (FOXP3+ [GeneID=50943]) versus B6 splenocytes."} {"geneset":"GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_DN","description":"Genes down-regulated in FoxP3-IRES-GFP: NOD T reg (FOXP3+ [GeneID=50943]) versus B6 splenocytes."} {"geneset":"GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_UP","description":"Genes up-regulated in Foxp3-ires-GFP T conv (FOXP3- [GeneID=50943]): B6 versus NOD background."} {"geneset":"GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN","description":"Genes down-regulated in T reg (FOXP3+ [GeneID=50943]) cells from NOD mice: Foxp3-Fusion-GFP versus Foxp3-ires-GFP."} {"geneset":"GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP","description":"Genes up-regulated in Foxp3-Fusion-GFP T conv (FOXP3- [GeneID=50943]): B6 versus NOD background."} {"geneset":"GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_DN","description":"Genes down-regulated in Foxp3-Fusion-GFP T conv (FOXP3- [GeneID=50943]): B6 versus NOD background."} {"geneset":"GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_DN","description":"Genes down-regulated in Foxp3-ires-GFP T conv (FOXP3- [GeneID=50943]): B6 versus NOD background."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_UP","description":"Genes up-regulated in hematopoietic stem cells versus lymphoid primed multipotent progenitors."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN","description":"Genes down-regulated in hematopoietic stem cells versus lymphoid primed multipotent progenitors."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_MULTIPOTENT_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_MULTIPOTENT_PROGENITOR_DN","description":"Genes down-regulated in hematopoietic stem cells versus multipotent progenitors."} {"geneset":"GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_UP","description":"Genes up-regulated in granulocyte-monocyte progenitor versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_DN","description":"Genes down-regulated in granulocyte-monocyte progenitor versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_MULTIPOTENT_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_MULTIPOTENT_PROGENITOR_UP","description":"Genes up-regulated in hematopoietic stem cells versus multipotent progenitors."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_COMMON_LYMPHOID_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_COMMON_LYMPHOID_PROGENITOR_DN","description":"Genes down-regulated in multipotent progenitors versus common lymphoid progenitors."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_UP","description":"Genes up-regulated in multipotent progenitors versus pro-B cells."} {"geneset":"GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_UP","description":"Genes up-regulated in NK cells: RAG2 [GeneID=5897] knockout versus RAG2 and ETS1 [GeneID=5897;2113] knockout."} {"geneset":"GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_DN","description":"Genes down-regulated in NK cells: RAG2 [GeneID=5897] knockout versus RAG2 and ETS1 [GeneID=5897;2113] knockout."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_DN","description":"Genes down-regulated in multipotent progenitors versus CD4 [GeneID=920] T cells."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP","description":"Genes up-regulated in multipotent progenitors versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN","description":"Genes down-regulated in multipotent progenitors versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_UP","description":"Genes up-regulated in multipotent progenitors versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_DN","description":"Genes down-regulated in multipotent progenitors versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_UP","description":"Genes up-regulated in lymphoid primed multipotent progenitors versus common lymphoid progenitors."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN","description":"Genes down-regulated in lymphoid primed multipotent progenitors versus common lymphoid progenitors."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_PRO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_PRO_BCELL_UP","description":"Genes up-regulated in lymphoid primed multipotent progenitors versus pro-B cells."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_PRO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_PRO_BCELL_DN","description":"Genes down-regulated in lymphoid primed multipotent progenitors versus pro-B cells."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_UP","description":"Genes up-regulated in lymphoid primed multipotent progenitors versus CD4 [GeneID=920] T cells."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_DN","description":"Genes down-regulated in lymphoid primed multipotent progenitors versus CD4 [GeneID=920] T cells."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP","description":"Genes up-regulated in lymphoid primed multipotent progenitors versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_DN","description":"Genes down-regulated in lymphoid primed multipotent progenitors versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_UP","description":"Genes up-regulated in lymphoid primed multipotent progenitors versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_DN","description":"Genes down-regulated in lymphoid primed multipotent progenitors versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_UP","description":"Genes up-regulated in common lymphoid progenitor versus pro-B cells."} {"geneset":"GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_DN","description":"Genes down-regulated in common lymphoid progenitor versus pro-B cells."} {"geneset":"GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_UP","description":"Genes up-regulated in common lymphoid progenitors versus CD4 [GeneID=920] T cells."} {"geneset":"GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_DN","description":"Genes down-regulated in common lymphoid progenitors versus CD4 [GeneID=920] T cells."} {"geneset":"GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP","description":"Genes up-regulated in common lymphoid progenitors versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN","description":"Genes down-regulated in common lymphoid progenitors versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_UP","description":"Genes up-regulated in common lymphoid progenitors versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_DN","description":"Genes down-regulated in common lymphoid progenitors versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_COMMON_LYMPHOID_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_COMMON_LYMPHOID_PROGENITOR_UP","description":"Genes up-regulated in hematopoietic stem cells versus common lymphoid progenitors."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_COMMON_LYMPHOID_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_COMMON_LYMPHOID_PROGENITOR_DN","description":"Genes down-regulated in hematopoietic stem cells versus common lymphoid progenitors."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_UP","description":"Genes up-regulated in hematopoietic stem cells versus pro-B cells."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_DN","description":"Genes down-regulated in hematopoietic stem cells versus pro-B cells."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP","description":"Genes up-regulated in hematopoietic stem cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_DN","description":"Genes down-regulated in hematopoietic stem cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_UP","description":"Genes 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{"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_UP","description":"Genes up-regulated in multipotent progenitors (MPP) versus lymphoid primed MPP cells."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN","description":"Genes down-regulated in multipotent progenitors (MPP) versus lymphoid primed MPP cells."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_COMMON_LYMPHOID_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_COMMON_LYMPHOID_PROGENITOR_UP","description":"Genes up-regulated in multipotent progenitors versus common lymphoid progenitors."} {"geneset":"GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN","description":"Genes down-regulated in pro-B cells versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_PRO_BCELL_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_PRO_BCELL_VS_CD4_TCELL_UP","description":"Genes up-regulated in pro-B cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN","description":"Genes down-regulated in multipotent progenitors versus pro-B cells."} {"geneset":"GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP","description":"Genes up-regulated in multipotent progenitors versus CD4 [GeneID=920] 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up-regulated in CD4 [GeneID=920] versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP","description":"Genes up-regulated in pro-B cells versus granulocyte-monocyte progenitors."} {"geneset":"GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells versus RAG2 [GeneID=5897] knockout NK cells."} {"geneset":"GSE37301_PRO_BCELL_VS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37301_PRO_BCELL_VS_CD4_TCELL_DN","description":"Genes down-regulated in pro-B cells versus CD4 [GeneID=920] T cells."} {"geneset":"GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP","description":"Genes up-regulated in dendritic cells: unstimulated wildtype versus KDM4D [GeneID=55693] knockdown (shRNA) stimulated by LPS."} {"geneset":"GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN","description":"Genes down-regulated in dendritic cells: unstimulated wildtype versus KDM4D [GeneID=55693] knockdown (shRNA) stimulated by LPS."} {"geneset":"GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN","description":"Genes down-regulated in dendritic cells stimulated by LPS: wildtype versus KDM4D [GeneID=55693]."} {"geneset":"GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_DN","description":"Genes down-regulated in dendritic cells: unstimulated versus LPS."} {"geneset":"GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP","description":"Genes up-regulated in dendritic cells stimulated by LPS: wildtype versus KDM4D [GeneID=55693]."} {"geneset":"GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_UP","description":"Genes up-regulated in dendritic cells: unstimulated versus LPS."} {"geneset":"GSE34217_MIR17_92_OVEREXPRESS_VS_WT_ACT_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34217_MIR17_92_OVEREXPRESS_VS_WT_ACT_CD8_TCELL_DN","description":"Genes down-regulated in act CD8 T cells: over-expressing MIR17HG [GeneID=407975] versus activated control."} {"geneset":"GSE34217_MIR17_92_OVEREXPRESS_VS_WT_ACT_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34217_MIR17_92_OVEREXPRESS_VS_WT_ACT_CD8_TCELL_UP","description":"Genes up-regulated in act CD8 T cells: over-expressing MIR17HG [GeneID=407975] versus activated control."} {"geneset":"GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_UP","description":"Genes up-regulated in CD44 low [GeneID=960] CD8 T cells: wildtype versus RC3H1 [GeneID=149041] knockout."} {"geneset":"GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_DN","description":"Genes down-regulated in CD44 low [GeneID=960] CD8 T cells: wildtype versus RC3H1 [GeneID=149041] knockout."} {"geneset":"GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: Th1 versus Th17 enriched."} {"geneset":"GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: Th1 versus Th17 negative."} {"geneset":"GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: Th1 versus Th17 negative."} {"geneset":"GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: Th1 versus Th17 enriched."} {"geneset":"GSE32901_NAIVE_VS_TH1_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_NAIVE_VS_TH1_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: naü¾™¦”¼ve versus Th1."} {"geneset":"GSE32901_NAIVE_VS_TH17_ENRICHED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_NAIVE_VS_TH17_ENRICHED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] naü¾™¦”¼ve versus Th17 enriched."} {"geneset":"GSE32901_NAIVE_VS_TH17_ENRICHED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_NAIVE_VS_TH17_ENRICHED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] naü¾™¦”¼ve versus Th17 enriched."} {"geneset":"GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] Th17 T cells: enriched versus negative."} {"geneset":"GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: naü¾™¦”¼ve versus Th17 negative."} {"geneset":"GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] Th17 T cells: enriched versus negative."} {"geneset":"GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: naü¾™¦”¼ve versus Th17 negative."} {"geneset":"GSE32901_NAIVE_VS_TH1_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32901_NAIVE_VS_TH1_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: naü¾™¦”¼ve versus Th1."} {"geneset":"GSE36095_WT_VS_HDAC9_KO_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36095_WT_VS_HDAC9_KO_TREG_UP","description":"Genes up-regulated in T reg: wildtype versus HDAC9 [GeneID=9734] knockout."} {"geneset":"GSE36095_WT_VS_HDAC9_KO_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36095_WT_VS_HDAC9_KO_TREG_DN","description":"Genes down-regulated in T reg: wildtype versus HDAC9 [GeneID=9734] knockout."} {"geneset":"GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN","description":"Genes down-regulated in visceral adipose tissue of aged mice: T reg versus T conv."} {"geneset":"GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_DN","description":"Genes down-regulated in T conv cells from aged PPARG [GeneID=5468] knockout mice: visceral adipose tissue versus lymph node."} {"geneset":"GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP","description":"Genes up-regulated in visceral adipose tissue of aged mice: T reg versus T conv."} {"geneset":"GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_UP","description":"Genes up-regulated in T reg of aged mice: visceral adipose tissue versus lymph node."} {"geneset":"GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN","description":"Genes down-regulated in T reg of aged mice: visceral adipose tissue versus lymph node."} {"geneset":"GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TCONV_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TCONV_CD4_TCELL_UP","description":"Genes up-regulated in T conv from aged mice: visceral adipose tissue versus lymph node."} {"geneset":"GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TCONV_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TCONV_CD4_TCELL_DN","description":"Genes down-regulated in T conv from aged mice: visceral adipose tissue versus lymph node."} {"geneset":"GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_UP","description":"Genes up-regulated in T reg cells from aged PPARG [GeneID=5468] knockout mice: visceral adipose tissue versus lymph node."} {"geneset":"GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_DN","description":"Genes down-regulated in T reg cells from aged PPARG [GeneID=5468] knockout mice: visceral adipose tissue versus lymph node."} {"geneset":"GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_UP","description":"Genes up-regulated in T conv cells from aged PPARG 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{"geneset":"GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP","description":"Genes up-regulated in visceral adipose tissue from aged PPARG [GeneID=5468] knockout mice: T reg versus T conv."} {"geneset":"GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN","description":"Genes down-regulated in visceral adipose tissue from aged PPARG [GeneID=5468] knockout mice: T reg versus T conv."} {"geneset":"GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_UP","description":"Genes up-regulated in lymph node from aged mice: T reg versus T conv."} {"geneset":"GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_DN","description":"Genes down-regulated in lymph node from aged mice: T reg versus T conv."} {"geneset":"GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_UP","description":"Genes up-regulated in lymph node from aged PPARG [GeneID=5468] knockout mice: T reg versus T conv."} {"geneset":"GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_DN","description":"Genes down-regulated in lymph node from aged PPARG [GeneID=5468] knockout mice: T reg versus T conv."} {"geneset":"GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_UP","description":"Genes up-regulated in T reg from visceral adipose tissue of aged mice: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN","description":"Genes down-regulated in T reg from visceral adipose tissue of aged mice: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_UP","description":"Genes up-regulated in T conv from visceral adipose tissue in aged mice: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_DN","description":"Genes down-regulated in T conv from visceral adipose tissue in aged mice: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] over-expressing: FOXP3 [GeneID=50943] and PPARg1 form of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]."} {"geneset":"GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] over-expressing: FOXP3 [GeneID=50943] and PPARg2 form of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]."} {"geneset":"GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] over-expressing: FOXP3 [GeneID=50943] and PPARg2 form of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]."} {"geneset":"GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943] and PPARg2 form of PPARG [GeneID=5468]."} {"geneset":"GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943] and PPARg2 form of PPARG [GeneID=5468]."} {"geneset":"GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]."} {"geneset":"GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]."} {"geneset":"GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg2 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]."} {"geneset":"GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg2 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]."} {"geneset":"GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468]: untreated versus GW1929 [PubChem=6518171]."} {"geneset":"GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468]: untreated versus GW1929 [PubChem=6518171]."} {"geneset":"GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 form of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 form of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T ceels over-expressing FOXP3 [GeneID=920] and PPARg1 isoform of PPARG [GeneID=5468]: untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T ceels over-expressing FOXP3 [GeneID=920] and PPARg1 isoform of PPARG [GeneID=5468]: untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468]: GW1929 [PubChem=6518171] versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468]: GW1929 [PubChem=6518171] versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468]: GW1929 [PubChem=6518171] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468]: GW1929 [PubChem=6518171] versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells treated with rosiglitazone [PubChem=77999] and over-expressing: FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943] and PPARg2 isoform of PPARG [GeneID=5468]."} {"geneset":"GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells treated with rosiglitazone [PubChem=77999] and over-expressing: FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943] and PPARg2 isoform of PPARG [GeneID=5468]."} {"geneset":"GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and Pparg2 isoform of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_FOXP3_TRASDUCED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_FOXP3_TRASDUCED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943]: untreated versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_FOXP3_TRASDUCED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_FOXP3_TRASDUCED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943]: untreated versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells over-expressing: FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943] and PPARg2 isoform of PPARG [GeneID=5468]."} {"geneset":"GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN","description":"Genes down-regulated in PPARg1 Foxp3 transduced CD4 T cell versus PPARg2 Foxp3 transduced CD4 T cell."} {"geneset":"GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] over-expressing: FOXP3 [GeneID=50943] and PPARg1 form of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]."} {"geneset":"GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and Pparg1 isoform of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and Pparg1 isoform of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and Pparg2 isoform of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]."} {"geneset":"GSE37532_WT_VS_PPARG_KO_LN_TCONV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37532_WT_VS_PPARG_KO_LN_TCONV_DN","description":"Genes down-regulated in T conv from lymph node of elderly (retired breeder) mice: wildtype versus PPARG [GeneID=5468] knockout."} {"geneset":"GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP","description":"Genes up-regulated in B lymphocytes: light zone versus dark zone."} {"geneset":"GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN","description":"Genes down-regulated in B lymphocytes: light zone versus dark zone."} {"geneset":"GSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP","description":"Genes up-regulated in B lymphocytes: light zone versus dark zone."} {"geneset":"GSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN","description":"Genes down-regulated in B lymphocytes: light zone versus dark zone."} {"geneset":"GSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_DN","description":"Genes down-regulated in CD4 [GeneID=920] cells after immunization: wildtype versus CTLA4 [GeneID=1493] knockout."} {"geneset":"GSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_UP","description":"Genes up-regulated in CD4 [GeneID=920] cells after immunization: wildtype versus CTLA4 [GeneID=1493] knockout."} {"geneset":"GSE39022_LN_VS_SPLEEN_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39022_LN_VS_SPLEEN_DC_UP","description":"Genes up-regulated in dendritic cells from: lymph node versus spleen."} {"geneset":"GSE39022_LN_VS_SPLEEN_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39022_LN_VS_SPLEEN_DC_DN","description":"Genes down-regulated in dendritic cells from: lymph node versus spleen."} {"geneset":"GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP","description":"Genes up-regulated in lymphoid primed multipotent progenitors: wildtype versus LYL1 [GeneID=4066] knockout."} {"geneset":"GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN","description":"Genes down-regulated in lymphoid primed multipotent progenitors: wildtype versus LYL1 [GeneID=4066] knockout."} {"geneset":"GSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_DN","description":"Genes down-regulated in CD69- KRLG1- [GeneID=969;10219] T reg: SELL high [GeneID=6402] versus SELL low [GeneID=6402]."} {"geneset":"GSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_UP","description":"Genes up-regulated in CD69- KRLG1- [GeneID=969;10219] T reg: SELL high [GeneID=6402] versus SELL low [GeneID=6402]."} {"geneset":"GSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_UP","description":"Genes up-regulated in KLRG1- [GeneID=10219] T reg:SELL high CD69- [GeneID=6402;969] versus SELL low CD69+ [GeneID=6402;969]."} {"geneset":"GSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_DN","description":"Genes down-regulated in KLRG1- [GeneID=10219] T reg:SELL high CD69- [GeneID=6402;969] versus SELL low CD69+ [GeneID=6402;969]."} {"geneset":"GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_DN","description":"Genes down-regulated in KLRG1- SELL low [GeneID=10219;6402] T reg: CD69- [GeneID=969] versus CD69+ [GeneID=969]."} {"geneset":"GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP","description":"Genes up-regulated in KLRG1- SELL low [GeneID=10219;6402] T reg: CD69- [GeneID=969] versus CD69+ [GeneID=969]."} {"geneset":"GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with heterozygous knockout of HDAC3 [GeneID=8841]: untreated versus LPS."} {"geneset":"GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with knockout of HDAC3 [GeneID=8841]: untreated versus LPS."} {"geneset":"GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with heterozygous knockout of HDAC3 [GeneID=8841]: untreated versus LPS."} {"geneset":"GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with knockout of HDAC3 [GeneID=8841]: untreated versus LPS."} {"geneset":"GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with knockout of HDAC3 [GeneID=8841]: heterozygous versus homozygous."} {"geneset":"GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with knockout of HDAC3 [GeneID=8841]: heterozygous versus homozygous."} {"geneset":"GSE33162_HDAC3_KO_VS_HDAC3_KO_4H_LPS_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33162_HDAC3_KO_VS_HDAC3_KO_4H_LPS_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophages with knockout of HDAC3 [GeneID=8841] after LPS treatment: heterozygous versus homozygous."} {"geneset":"GSE33162_HDAC3_KO_VS_HDAC3_KO_4H_LPS_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33162_HDAC3_KO_VS_HDAC3_KO_4H_LPS_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophages with knockout of HDAC3 [GeneID=8841] after LPS treatment: heterozygous versus homozygous."} {"geneset":"GSE34006_WT_VS_A2AR_KO_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34006_WT_VS_A2AR_KO_TREG_DN","description":"Genes down-regulated in T reg: wildtype versus ADORA2A [GeneID=135]."} {"geneset":"GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_UP","description":"Genes up-regulated in T reg: untreated versus ZM 241385 [PubChem=176407]."} {"geneset":"GSE34006_WT_VS_A2AR_KO_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34006_WT_VS_A2AR_KO_TREG_UP","description":"Genes up-regulated in T reg: wildtype versus ADORA2A [GeneID=135]."} {"geneset":"GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_DN","description":"Genes down-regulated in T reg: untreated ADORA2A [GeneID=135] knockout versus wildtype treated by ZM 241385 [PubChem=176407]."} {"geneset":"GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_DN","description":"Genes down-regulated in T reg: untreated versus ZM 241385 [PubChem=176407]."} {"geneset":"GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_UP","description":"Genes up-regulated in T reg: untreated ADORA2A [GeneID=135] knockout versus wildtype treated by ZM 241385 [PubChem=176407]."} {"geneset":"GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_UP","description":"Genes up-regulated in Ly6C monocytes: high versus low."} {"geneset":"GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_DN","description":"Genes down-regulated in Ly6C monocytes: high versus low."} {"geneset":"GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_UP","description":"Genes up-regulated in Ly6C low monocytes: untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_DN","description":"Genes down-regulated in Ly6C low monocytes: untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_UP","description":"Genes up-regulated in monocytes treated by rosiglitazone [PubChem=77999]: Ly6C high versus Ly6C low."} {"geneset":"GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP","description":"Genes up-regulated in Ly6C high monocytes: untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_DN","description":"Genes down-regulated in Ly6C high monocytes: untreated versus rosiglitazone [PubChem=77999]."} {"geneset":"GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_DN","description":"Genes down-regulated in monocytes treated by rosiglitazone [PubChem=77999]: Ly6C high versus Ly6C low."} {"geneset":"GSE39864_WT_VS_GATA3_KO_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39864_WT_VS_GATA3_KO_TREG_DN","description":"Genes down-regulated in T reg cells: wildtype versus GATA3 [GeneID=2625] knockout."} {"geneset":"GSE39864_WT_VS_GATA3_KO_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39864_WT_VS_GATA3_KO_TREG_UP","description":"Genes up-regulated in T reg cells: wildtype versus GATA3 [GeneID=2625] knockout."} {"geneset":"GSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells: ITGAE- [GeneID=3682] from spleen versus ITGAE+ [GeneID=3682] from brain."} {"geneset":"GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells, ITGAE- [GeneID=3682] population: brain versus spleen sources."} {"geneset":"GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells from brain: ITGAE- [GeneID=3682] versus ITGAE+ [GeneID=3682]."} {"geneset":"GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in memory CD8 T cells from brain: ITGAE- [GeneID=3682] versus ITGAE+ [GeneID=3682]."} {"geneset":"GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells, ITGAE- [GeneID=3682] population: brain versus spleen sources."} {"geneset":"GSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in memory CD8 T cells: ITGAE- [GeneID=3682] from spleen versus ITGAE+ [GeneID=3682] from brain."} {"geneset":"GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_UP","description":"Genes up-regulated in the bone marrow CD34+ [GeneID=947] cells: CD38- [GeneID=952] versus MME+ [GeneID=4311]."} {"geneset":"GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN","description":"Genes down-regulated in the bone marrow CD34+ [GeneID=947] cells: CD38- [GeneID=952] versus MME+ [GeneID=4311]."} {"geneset":"GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_UP","description":"Genes up-regulated in the bone marrow CD34+ [GeneID=947] cells: MME- SELL+[GeneID=4311;6402] versus MME+ [GeneID=4311]."} {"geneset":"GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN","description":"Genes down-regulated in the bone marrow CD34+ [GeneID=947] cells: MME- SELL+[GeneID=4311;6402] versus MME+ [GeneID=4311]."} {"geneset":"GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_UP","description":"Genes up-regulated in the bone marrow CD34+ [GeneID=947] cells: CD38- [GeneID=952] versus MME- SELL+ [GeneID=4311;6402]."} {"geneset":"GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_DN","description":"Genes down-regulated in the bone marrow CD34+ [GeneID=947] cells: CD38- [GeneID=952] versus MME- SELL+ [GeneID=4311;6402]."} {"geneset":"GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of IRF4 [GeneID=3662]."} {"geneset":"GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of IRF4 [GeneID=3662]."} {"geneset":"GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of SATB1 [GeneID=6304]."} {"geneset":"GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of SATB1 [GeneID=6304]."} {"geneset":"GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of LEF1 [GeneID=51176]."} {"geneset":"GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of LEF1 [GeneID=51176]."} {"geneset":"GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of XBP1 [GeneID=7494]."} {"geneset":"GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of XBP1 [GeneID=7494]."} {"geneset":"GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of GATA1 [GeneID=2623]."} {"geneset":"GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of GATA1 [GeneID=2623]."} {"geneset":"GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of IKZF2 [GeneID=22807]."} {"geneset":"GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of IKZF2 [GeneID=22807]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of IKZF4 and FOXP3 [GeneID=64375;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of IKZF4 and FOXP3 [GeneID=64375;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of PBX1 and FOXP3 [GeneID=5087;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of PBX1 and FOXP3 [GeneID=5087;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of GATA1 and FOXP3 [GeneID=2623;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of GATA1 and FOXP3 [GeneID=2623;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of LEF1 and FOXP3 [GeneID=51176;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of LEF1 and FOXP3 [GeneID=51176;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of IRF4 and FOXP3 [GeneID=3662;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of IRF4 and FOXP3 [GeneID=3662;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of SATB1 and FOXP3 [GeneID=6304;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of SATB1 and FOXP3 [GeneID=6304;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of XBP1 and FOXP3 [GeneID=7494;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of XBP1 and FOXP3 [GeneID=7494;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of IKZF2 and FOXP3 [GeneID=22807;50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of IKZF2 and FOXP3 [GeneID=22807;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus IKZF4 and FOXP3 [GeneID=64375;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus IKZF4 and FOXP3 [GeneID=64375;50943]."} {"geneset":"GSE40273_XBP1_KO_VS_WT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40273_XBP1_KO_VS_WT_TREG_UP","description":"Genes up-regulated in T reg: XBP1 [GeneID=7494] knockout versus wildtype."} {"geneset":"GSE40273_XBP1_KO_VS_WT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40273_XBP1_KO_VS_WT_TREG_DN","description":"Genes down-regulated in T reg: XBP1 [GeneID=7494] knockout versus wildtype."} {"geneset":"GSE40273_EOS_KO_VS_WT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40273_EOS_KO_VS_WT_TREG_UP","description":"Genes up-regulated in T reg: IKZF4 [GeneID=64375] versus wildtype."} {"geneset":"GSE40273_EOS_KO_VS_WT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40273_EOS_KO_VS_WT_TREG_DN","description":"Genes down-regulated in T reg: IKZF4 [GeneID=64375] versus wildtype."} {"geneset":"GSE40273_GATA1_KO_VS_WT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40273_GATA1_KO_VS_WT_TREG_UP","description":"Genes up-regulated in T reg: GATA1 [GeneID=2623] knockout versus wildtype."} {"geneset":"GSE40273_GATA1_KO_VS_WT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40273_GATA1_KO_VS_WT_TREG_DN","description":"Genes down-regulated in T reg: GATA1 [GeneID=2623] knockout versus wildtype."} {"geneset":"GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of FOXP3 [GeneID=50943]."} {"geneset":"GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of FOXP3 [GeneID=50943]."} {"geneset":"GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv: control versus over-expression of IKZF4 [GeneID=64375]."} {"geneset":"GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv: control versus over-expression of IKZF4 [GeneID=64375]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus SATB1 and FOXP3 [GeneID=6304;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus SATB1 and FOXP3 [GeneID=6304;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus XBP1 and FOXP3 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SATB1 and FOX3P [GeneID=6304;50943]."} {"geneset":"GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing LEF1 [GeneID=51176] versus LEF1 and FOX3P [GeneID=51176;50943]."} {"geneset":"GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing LEF1 [GeneID=51176] versus LEF1 and FOX3P [GeneID=51176;50943]."} {"geneset":"GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing XBP1 [GeneID=7494] versus XBP1 and FOX3P [GeneID=7494;50943]."} {"geneset":"GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing XBP1 [GeneID=7494] versus XBP1 and FOX3P [GeneID=7494;50943]."} {"geneset":"GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing GATA1 [GeneID=2623] versus GATA1 and FOX3P [GeneID=2623;50943]."} {"geneset":"GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing GATA1 [GeneID=2623] versus GATA1 and FOX3P [GeneID=2623;50943]."} {"geneset":"GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing IKZF2 [GeneID=22807] versus IKZF2 and FOX3P [GeneID=22807;50943]."} {"geneset":"GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing IKZF2 [GeneID=22807] versus IKZF2 and FOX3P [GeneID=22807;50943]."} {"geneset":"GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T conv over-expressing: IKZF4 and LEF1 [GeneID=64375;52276] versus GATA1 and SATB1 [GeneID=6304] versus GATA1 and SATB1 [GeneID=6304;2623]."} {"geneset":"GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T conv over-expressing: IKZF4 and LEF1 [GeneID=64375;52276] versus GATA1 and SATB1 [GeneID=6304] versus GATA1 and SATB1 [GeneID=6304;2623]."} {"geneset":"GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T conv: over-expressing IKZF4 and LEF1 [GeneID=64375;52276] versus control."} {"geneset":"GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T conv: over-expressing IKZF4 and LEF1 [GeneID=64375;52276] versus control."} {"geneset":"GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T conv over-expressing: GATA1 and SATB1 [GeneID=6304;2623] versus control."} {"geneset":"GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T conv over-expressing: GATA1 and SATB1 [GeneID=6304;2623] versus control."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus IRF4 and FOXP3 [GeneID=3662;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing FOXP3 [GeneID=50943] versus GATA1 and FOXP3 [GeneID=2623;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus PBX1 and FOXP3 [GeneID=5087;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus PBX1 and FOXP3 [GeneID=5087;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing FOXP3 [GeneID=50943] versus GATA1 and FOXP3 [GeneID=2623;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus LEF1 and FOXP3 [GeneID=51176;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus LEF1 and FOXP3 [GeneID=51176;50943]."} {"geneset":"GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus IRF4 and FOXP3 [GeneID=3662;50943]."} {"geneset":"GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_DN","description":"Genes down-regulated in T reg: NRP1+ [GeneID=8829] versus NRP1- [GeneID=8829]."} {"geneset":"GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_UP","description":"Genes up-regulated in T reg: NRP1+ [GeneID=8829] versus NRP1- [GeneID=8829]."} {"geneset":"GSE40443_INDUCED_VS_TOTAL_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40443_INDUCED_VS_TOTAL_TREG_UP","description":"Genes up-regulated in T reg: induced versus total."} {"geneset":"GSE40443_INDUCED_VS_TOTAL_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40443_INDUCED_VS_TOTAL_TREG_DN","description":"Genes down-regulated in T reg: induced versus total."} {"geneset":"GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus day 8 after LCMV infection."} {"geneset":"GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus day 8 after LCMV infection."} {"geneset":"GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: wildtype versus STAT1 [GeneID=6772] knockout."} {"geneset":"GSE40666_WT_VS_STAT1_KO_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_WT_VS_STAT1_KO_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: wildtype versus STAT1 [GeneID=6772] knockout."} {"geneset":"GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP","description":"Genes up-regulated in CD8 T cells treated by interferon 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STAT4 [GeneID=6775]."} {"geneset":"GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP","description":"Genes up-regulated in CD8 T cells treated by inteferon alpha: wildtype versus STAT4 [GeneID=6775] knockout."} {"geneset":"GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN","description":"Genes down-regulated in CD8 T cells treated by inteferon alpha: wildtype versus STAT4 [GeneID=6775] knockout."} {"geneset":"GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP","description":"Genes up-regulated in CD8 T cells treated by interferon alpha: STAT1 [GeneID=6772] knockout versus STAT4 [GeneID=6775]."} {"geneset":"GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN","description":"Genes down-regulated in CD8 T cells treated by interferon alpha: STAT1 [GeneID=6772] knockout versus STAT4 [GeneID=6775]."} {"geneset":"GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: STAT1 [GeneID=6772] knockout versus STAT4 [GeneID=6775] knockout."} {"geneset":"GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: STAT1 [GeneID=6772] knockout versus STAT4 [GeneID=6775] knockout."} {"geneset":"GSE40666_WT_VS_STAT4_KO_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_WT_VS_STAT4_KO_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: wildtype versus STAT4 [GeneID=6775] knockout."} {"geneset":"GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_UP","description":"Genes up-regulated in CD8 T cells: untreated versus interferon alpha."} {"geneset":"GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_DN","description":"Genes down-regulated in CD8 T cells: untreated versus interferon alpha."} {"geneset":"GSE40666_WT_VS_STAT4_KO_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_WT_VS_STAT4_KO_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: wildtype versus STAT4 [GeneID=6775] knockout."} {"geneset":"GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_DN","description":"Genes down-regulated in CD8 T cells at day 8 after LCMV infection: untreated versus interferon alpha."} {"geneset":"GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_UP","description":"Genes up-regulated in CD8 T cells with STAT1 [GeneID=6772]: untreated versus interferon alpha."} {"geneset":"GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN","description":"Genes down-regulated in CD8 T cells with STAT1 [GeneID=6772]: untreated versus interferon alpha."} {"geneset":"GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_UP","description":"Genes up-regulated in CD8 T cells at day 8 after LCMV infection: untreated versus interferon alpha."} {"geneset":"GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN","description":"Genes down-regulated in CD8 T cells with STAT4 [GeneID=6775]: untreated versus interferon alpha."} {"geneset":"GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_UP","description":"Genes up-regulated in CD8 T cells with STAT4 [GeneID=6775]: untreated versus interferon alpha."} {"geneset":"GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP","description":"Genes up-regulated in pancreatic CD8 T cells from mice with: type 1 diabetes mellitus versus healthy controls."} {"geneset":"GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_DN","description":"Genes down-regulated in pancreatic CD8 T cells from mice with: type 1 diabetes mellitus versus healthy controls."} {"geneset":"GSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP","description":"Genes up-regulated in dendritic cells: 2,4-dinitrofluorobenzene (DNFB) [PubChem=6264] versus diphenyleneiodonium (DPI) [PubChem=2733504]."} {"geneset":"GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_DN","description":"Genes down-regulated in dendritic cells: untreated versus diphenyleneiodonium (DPI) [PubChem=2733504]."} {"geneset":"GSE20727_CTRL_VS_H2O2_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_CTRL_VS_H2O2_TREATED_DC_DN","description":"Genes down-regulated in dendritic cells: untreated versus hydrogen peroxide [PubChem=784]."} {"geneset":"GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_UP","description":"Genes up-regulated in dendritic cells: untreated versus diphenyleneiodonium (DPI) [PubChem=2733504]."} {"geneset":"GSE20727_CTRL_VS_H2O2_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_CTRL_VS_H2O2_TREATED_DC_UP","description":"Genes up-regulated in dendritic cells: untreated versus hydrogen peroxide [PubChem=784]."} {"geneset":"GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN","description":"Genes down-regulated in dendritic cells: control versus 2,4-dinitrofluorobenzene (DNFB) [PubChem=6264] and diphenyleneiodonium (DPI) [PubChem=2733504]."} {"geneset":"GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN","description":"Genes down-regulated in dendritic cells: diphenyleneiodonium (DPI) [PubChem=2733504] versus DPI and 2,4-dinitrofluorobenzene (DNFB) [PubChem=6264]."} {"geneset":"GSE20727_CTRL_VS_DNFB_ALLERGEN_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_CTRL_VS_DNFB_ALLERGEN_TREATED_DC_DN","description":"Genes down-regulated in dendritic cells: untreated versus 2,4-dinitrofluorobenzene (DNFB) [PubChem=6264]."} {"geneset":"GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP","description":"Genes up-regulated in dendritic cells: control versus 2,4-dinitrofluorobenzene (DNFB) [PubChem=6264] and diphenyleneiodonium (DPI) [PubChem=2733504]."} {"geneset":"GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP","description":"Genes up-regulated in dendritic cells: diphenyleneiodonium (DPI) [PubChem=2733504] versus DPI and 2,4-dinitrofluorobenzene (DNFB) [PubChem=6264]."} {"geneset":"GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN","description":"Genes down-regulated in dendritic cells: hydrogen peroxide [PubChem=784] 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{"geneset":"GSE38304_MYC_NEG_VS_POS_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE38304_MYC_NEG_VS_POS_GC_BCELL_DN","description":"Genes down-regulated in germinal celter B lymphocytes: MYC- [GeneID=4609] versus MYC+ [GeneID=4609]."} {"geneset":"GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN","description":"Genes down-regulated in CD8 T cells 3 days after immunization: control versus IL2 [GeneID=3558] treatment."} {"geneset":"GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells after immunization: day 3 versus day 6."} {"geneset":"GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells after immunization: day 3 versus day 6."} {"geneset":"GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_UP","description":"Genes up-regulated in CD8 T cells 3 days after immunization: control versus IL2 [GeneID=3558] treatment."} {"geneset":"GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP","description":"Genes up-regulated in CD8 T cells after immunization: day 3 versus day 6 and IL2 [GeneID=3558] treatment."} {"geneset":"GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_DN","description":"Genes down-regulated in CD8 T cells after immunization: day 3 versus day 6 and IL2 [GeneID=3558] treatment."} {"geneset":"GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_UP","description":"Genes up-regulated in CD8 T cells 6 days after immunization: control versus IL2 [GeneID=3558] treatment."} {"geneset":"GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_DN","description":"Genes down-regulated in CD8 T cells 6 days after immunization: control versus IL2 [GeneID=3558] 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{"geneset":"GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_UP","description":"Genes up-regulated in Lung dendritic cell from Ad5 T424A hexon infection wildtype mice versus Lung dendritic cell from Ad5 T424A hexon inf IL-1R mice."} {"geneset":"GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_DN","description":"Genes down-regulated in Lung dendritic cell from Ad5 T424A hexon infection wildtype mice versus Lung dendritic cell from Ad5 T424A hexon inf IL-1R mice."} {"geneset":"GSE36078_UNTREATED_VS_AD5_INF_IL1R_KO_MOUSE_LUNG_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36078_UNTREATED_VS_AD5_INF_IL1R_KO_MOUSE_LUNG_DC_DN","description":"Genes down-regulated in Lung dendritic cell from untreated IL-1R mice versus Lung 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{"geneset":"GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_UP","description":"Genes up-regulated in marginal zone B cells versus day 7 germinal center B cells."} {"geneset":"GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN","description":"Genes down-regulated in marginal zone B cells versus day 7 germinal center B cells."} {"geneset":"GSE11961_MARGINAL_ZONE_BCELL_VS_PLASMA_CELL_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MARGINAL_ZONE_BCELL_VS_PLASMA_CELL_DAY7_UP","description":"Genes up-regulated in marginal zone B cells versus day 7 plasma cells."} {"geneset":"GSE11961_MARGINAL_ZONE_BCELL_VS_PLASMA_CELL_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MARGINAL_ZONE_BCELL_VS_PLASMA_CELL_DAY7_DN","description":"Genes down-regulated in marginal zone B cells versus day 7 plasma cells."} {"geneset":"GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_UP","description":"Genes up-regulated in marginal zone B cells versus day 40 memory B cells."} {"geneset":"GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_DN","description":"Genes down-regulated in marginal zone B cells versus day 40 memory B cells."} {"geneset":"GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN","description":"Genes down-regulated in day 7 germinal center B cells versus day 40 memory B cells."} {"geneset":"GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP","description":"Genes up-regulated in day 7 germinal center B cells versus day 40 germinal center B cells."} {"geneset":"GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN","description":"Genes down-regulated in day 7 germinal center B cells versus day 40 germinal center B cells."} {"geneset":"GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_UP","description":"Genes up-regulated in follicular B cells versus those stimulated with anti-IgM and CD40 [GeneID=958] for 6h."} {"geneset":"GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_DN","description":"Genes down-regulated in follicular B cells versus those stimulated with anti-IgM and CD40 [GeneID=958] for 6h."} {"geneset":"GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_UP","description":"Genes up-regulated in marginal zone B cells versus day 7 memory B cells."} {"geneset":"GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_DN","description":"Genes down-regulated in marginal zone B cells versus day 7 memory B cells."} {"geneset":"GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_UP","description":"Genes up-regulated in follicular B cells versus day 7 memory B cells."} {"geneset":"GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_DN","description":"Genes down-regulated in follicular B cells versus day 7 memory B cells."} {"geneset":"GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_UP","description":"Genes 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{"geneset":"GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP","description":"Genes up-regulated in marginal zone B lymphocytes: wildtype versus BCL6 [GeneID=604] knockout."} {"geneset":"GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN","description":"Genes down-regulated in marginal zone B lymphocytes: wildtype versus BCL6 [GeneID=604] knockout."} {"geneset":"GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP","description":"Genes up-regulated in marginal zone B lymphocytes with knockout of BCL6 [GeneID=604]: heterozygous versus homozygous."} {"geneset":"GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN","description":"Genes down-regulated in marginal zone B lymphocytes with knockout of BCL6 [GeneID=604]: heterozygous versus homozygous."} {"geneset":"GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_UP","description":"Genes up-regulated in follicular B lymphocytes versus marginal zone B cells."} {"geneset":"GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_DN","description":"Genes down-regulated in follicular B lymphocytes versus marginal zone B cells."} {"geneset":"GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_UP","description":"Genes up-regulated in heterozygous knockout of BCL6 [GeneID=604]: follicular versus marginal zone source."} {"geneset":"GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_DN","description":"Genes down-regulated in heterozygous knockout of BCL6 [GeneID=604]: follicular versus marginal zone source."} {"geneset":"GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN","description":"Genes down-regulated in day 7 memory B cells versus day 40 memory B cells."} {"geneset":"GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP","description":"Genes up-regulated in day 7 memory B cells versus day 40 germinal center B cells."} {"geneset":"GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN","description":"Genes down-regulated in day 7 memory B cells versus day 40 germinal center B cells."} {"geneset":"GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP","description":"Genes up-regulated in day 7 germinal center B cells versus day 7 plasma cells."} {"geneset":"GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN","description":"Genes down-regulated in day 7 germinal center B cells versus day 7 plasma cells."} {"geneset":"GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_UP","description":"Genes up-regulated in day 7 germinal center B cells versus day 40 memory B cells."} {"geneset":"GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP","description":"Genes up-regulated in day 7 memory B cells versus day 7 plasma cells."} {"geneset":"GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN","description":"Genes down-regulated in day 7 memory B cells versus day 7 plasma cells."} {"geneset":"GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_UP","description":"Genes up-regulated in day 7 memory B cells versus day 40 memory B cells."} {"geneset":"GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN","description":"Genes down-regulated in day 7 memory B cells versus day 7 germinal center B cells."} {"geneset":"GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_DN","description":"Genes down-regulated in follicular B cells versus marginal zone B cells."} {"geneset":"GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_DN","description":"Genes down-regulated in follicular B lymphocytes: wildtype versus BCL6 [GeneID=604] knockout."} {"geneset":"GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_UP","description":"Genes up-regulated in follicular B lymphocytes with BCL6 [GeneID=604] knockout: heterozygotic versus homozygotic strains."} {"geneset":"GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP","description":"Genes up-regulated in follicular B cells versus marginal zone B cells."} {"geneset":"GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_DN","description":"Genes down-regulated in day 40 memory B cells versus day 40 germinal center B cells."} {"geneset":"GSE28737_WT_VS_BCL6_HET_FOLLICULAR_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_WT_VS_BCL6_HET_FOLLICULAR_BCELL_DN","description":"Genes down-regulated in follicular B lymphocytes: wildtype versus heterozygotic knockout of BCL6 [GeneID=604]."} {"geneset":"GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_UP","description":"Genes up-regulated in day 7 plasma cells versus day 40 memory B cells."} {"geneset":"GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_DN","description":"Genes down-regulated in follicular B lymphocytes with BCL6 [GeneID=604] knockout: heterozygotic versus homozygotic strains."} {"geneset":"GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_UP","description":"Genes up-regulated in day 40 memory B cells versus day 40 germinal center B cells."} {"geneset":"GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_UP","description":"Genes up-regulated in follicular B lymphocytes: wildtype versus BCL6 [GeneID=604] knockout."} {"geneset":"GSE28737_WT_VS_BCL6_HET_FOLLICULAR_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28737_WT_VS_BCL6_HET_FOLLICULAR_BCELL_UP","description":"Genes up-regulated in follicular B lymphocytes: wildtype versus heterozygotic knockout of BCL6 [GeneID=604]."} {"geneset":"GSE11961_PLASMA_CELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_PLASMA_CELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP","description":"Genes up-regulated in day 7 plasma cells versus day 40 germinal center B cells."} {"geneset":"GSE11961_PLASMA_CELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_PLASMA_CELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN","description":"Genes down-regulated in day 7 plasma cells versus day 40 germinal center B cells."} {"geneset":"GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_DN","description":"Genes down-regulated in day 7 plasma cells versus day 40 memory B cells."} {"geneset":"GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_UP","description":"Genes up-regulated in Va14 invariant NKT cells: ZBTB7B [GeneID=51043] knockout versus wildtype."} {"geneset":"GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_DN","description":"Genes down-regulated in Va14 invariant NKT cells: ZBTB7B [GeneID=51043] knockout versus wildtype."} {"geneset":"GSE40493_BCL6_KO_VS_WT_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40493_BCL6_KO_VS_WT_TREG_UP","description":"Genes up-regulated in T reg: BCL6 [GeneID=604] knockout versus wildtype."} {"geneset":"GSE40493_BCL6_KO_VS_WT_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40493_BCL6_KO_VS_WT_TREG_DN","description":"Genes down-regulated in T reg: BCL6 [GeneID=604] knockout versus wildtype."} {"geneset":"GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PBMC): healthy donors versus patients with HCV infection."} {"geneset":"GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PBMC): healthy donors versus patients with HCV infection."} {"geneset":"GSE39556_CD8A_DC_VS_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39556_CD8A_DC_VS_NK_CELL_UP","description":"Genes up-regulated in CD8A [GeneID=925] dendritic cells versus NK cells."} {"geneset":"GSE39556_CD8A_DC_VS_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39556_CD8A_DC_VS_NK_CELL_DN","description":"Genes down-regulated in CD8A [GeneID=925] dendritic cells versus NK cells."} {"geneset":"GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_DN","description":"Genes down-regulated in CD8A [GeneID=935] dendritic cells: untreated versus poly(IC)."} {"geneset":"GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP","description":"Genes up-regulated in NK cells: untreated versus poly(IC)."} {"geneset":"GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN","description":"Genes down-regulated in NK cells: untreated versus poly(IC)."} {"geneset":"GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP","description":"Genes up-regulated in CD8A [GeneID=935] dendritic cells: untreated versus poly(IC)."} {"geneset":"GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN","description":"Genes down-regulated after poly(IC) injection: CD8A [GeneID=925] dendritic cells versus NK cells."} {"geneset":"GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_UP","description":"Genes up-regulated after poly(IC) injection: CD8A [GeneID=925] dendritic cells versus NK cells."} {"geneset":"GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP","description":"Genes up-regulated in DN3 thymocytes: wildtype versus TCF7 [GeneID=6932] knockout."} {"geneset":"GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN","description":"Genes down-regulated in DN3 thymocytes: wildtype versus TCF7 [GeneID=6932] knockout."} {"geneset":"GSE33292_DN3_THYMOCYTE_VS_TCELL_LYMPHOMA_FROM_TCF1_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33292_DN3_THYMOCYTE_VS_TCELL_LYMPHOMA_FROM_TCF1_KO_DN","description":"Genes down-regulated in TCF7 [GeneID=6932] knockout: DN3 thymocytes versus T cell lymphoma cells."} {"geneset":"GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_UP","description":"Genes up-regulated in wildtype DN3 thymocytes versus T cell lymphoma cells from TCF7 [GeneID=6932] knockout."} {"geneset":"GSE33292_DN3_THYMOCYTE_VS_TCELL_LYMPHOMA_FROM_TCF1_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33292_DN3_THYMOCYTE_VS_TCELL_LYMPHOMA_FROM_TCF1_KO_UP","description":"Genes up-regulated in TCF7 [GeneID=6932] knockout: DN3 thymocytes versus T cell lymphoma cells."} {"geneset":"GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_DN","description":"Genes down-regulated in wildtype DN3 thymocytes versus T cell lymphoma cells from TCF7 [GeneID=6932] knockout."} {"geneset":"GSE35543_IN_VIVO_NTREG_VS_IN_VITRO_ITREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35543_IN_VIVO_NTREG_VS_IN_VITRO_ITREG_DN","description":"Genes down-regulated in T reg: in vivo versus in vitro."} {"geneset":"GSE35543_IN_VIVO_NTREG_VS_CONVERTED_EX_ITREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35543_IN_VIVO_NTREG_VS_CONVERTED_EX_ITREG_UP","description":"Genes up-regulated in comparison between in vivo derived natural T reg (nTreg) and converted ex-iTreg (induced T reg that lost FOXP3 [GeneID=50943] expression)."} {"geneset":"GSE35543_IN_VIVO_NTREG_VS_IN_VITRO_ITREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35543_IN_VIVO_NTREG_VS_IN_VITRO_ITREG_UP","description":"Genes up-regulated in T reg: in vivo versus in vitro."} {"geneset":"GSE35543_IN_VIVO_NTREG_VS_CONVERTED_EX_ITREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35543_IN_VIVO_NTREG_VS_CONVERTED_EX_ITREG_DN","description":"Genes down-regulated in comparison between in vivo derived natural T reg (nTreg) and converted ex-iTreg (induced T reg that lost FOXP3 [GeneID=50943] expression)."} {"geneset":"GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_DN","description":"Genes down-regulated in comparison between in vitro derived induced T reg (iTreg) and converted ex iTreg."} {"geneset":"GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_UP","description":"Genes up-regulated in comparison between in vitro derived induced T reg (iTreg) and converted ex iTreg."} {"geneset":"GSE40655_FOXO1_KO_VS_WT_NTREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40655_FOXO1_KO_VS_WT_NTREG_UP","description":"Genes up-regulated in normal T reg (nTreg): FOXO1 [GeneID=2308] versus wildtype."} {"geneset":"GSE40655_FOXO1_KO_VS_WT_NTREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE40655_FOXO1_KO_VS_WT_NTREG_DN","description":"Genes down-regulated in normal T reg (nTreg): FOXO1 [GeneID=2308] versus wildtype."} {"geneset":"GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN","description":"Genes down-regulated in splenocytes: 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{"geneset":"GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_UP","description":"Genes up-regulated in splenocytes: control versus infected with Baki-1 MuLV virus."} {"geneset":"GSE24671_BAKIMULC_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE24671_BAKIMULC_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN","description":"Genes down-regulated in splenocytes with viral infection: Baki-1 MuLV versus Sendai."} {"geneset":"GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 8 versus day 15."} {"geneset":"GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 8 versus day 15."} {"geneset":"GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP","description":"Genes up-regulated in CD8 T cells during chronic infection with LCMV-Clone 13: effectors at day 15 versus exhausted at day 30."} {"geneset":"GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN","description":"Genes down-regulated in CD8 T cells during chronic infection with LCMV-Clone 13: effectors at day 15 versus 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{"geneset":"GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP","description":"Genes up-regulated in CD8 T cells, acute infection with LCMV-Armstrong: effectors at day 6 versus memory at day 30."} {"geneset":"GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN","description":"Genes down-regulated in CD8 T cells, acute infection with LCMV-Armstrong: effectors at day 6 versus memory at day 30."} {"geneset":"GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP","description":"Genes up-regulated in CD8 T cells, acute infection with LCMV-Armstrong: effectors at day 8 versus memory at 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{"geneset":"GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN","description":"Genes down-regulated in CD8 T cells, acute infection with LCMV-Armstrong: effectors at day 8 versus memory at day 30."} {"geneset":"GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 6 versus day 8."} {"geneset":"GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 6 versus day 8."} {"geneset":"GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP","description":"Genes up-regulated in CD8 T cells during chronic infection with LCMV-Clone 13: effectors at day 6 versus exhausted at day 30."} {"geneset":"GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN","description":"Genes down-regulated in CD8 T cells during chronic infection with LCMV-Clone 13: effectors at day 6 versus exhausted at day 30."} {"geneset":"GSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP","description":"Genes up-regulated in CD8 T cells during chronic infection with LCMV-Clone 13: 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LCMV-Armstrong."} {"geneset":"GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus effectors at day 15 after acute infection with LCMV-Armstrong."} {"geneset":"GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus effectors at day 15 after acute infection with LCMV-Armstrong."} {"geneset":"GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus memory at day 30 after acute infection with LCMV-Armstrong."} {"geneset":"GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus memory at day 30 after acute infection with LCMV-Armstrong."} {"geneset":"GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus effectors at day 8 chronic infection with LCMV-clone 13."} {"geneset":"GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus effectors at day 8 chronic infection with LCMV-clone 13."} {"geneset":"GSE41867_NAIVE_VS_DAY15_LCMV_CONE13_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY15_LCMV_CONE13_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus effectors at day 15 chronic infection with LCMV-clone 13."} {"geneset":"GSE41867_NAIVE_VS_DAY15_LCMV_CONE13_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY15_LCMV_CONE13_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: naü¾™¦”¼ve versus effectors at day 15 chronic infection with LCMV-clone 13."} {"geneset":"GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: naü¾™¦”¼ve versus exhausted at day 30 chronic infection with LCMV-clone 13."} {"geneset":"GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T effector cells at day 15 of: acute infection with LCMV-Armstrong versus chronic infection with LCMV-Clone 13."} {"geneset":"GSE41867_DAY6_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 6 versus day 15."} {"geneset":"GSE41867_DAY6_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 6 versus day 15."} {"geneset":"GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T effectors at acute infection with LCMV-Armstrong: day 6 versus day 15."} {"geneset":"GSE41867_DAY8_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY8_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T effectors at acute infection with LCMV-Armstrong: day 8 versus day 15."} {"geneset":"GSE41867_DAY8_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY8_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T effectors at acute infection with LCMV-Armstrong: day 8 versus day 15."} {"geneset":"GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T effectors at acute infection with LCMV-Armstrong: day 6 versus day 15."} {"geneset":"GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN","description":"Genes down-regulated in CD5 T cells at acute infection with LCMV-Armstrong: effectors at day 15 versus memory at day 30."} {"geneset":"GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T effector cells at day 15 of: acute infection with LCMV-Armstrong versus chronic infection with LCMV-Clone 13."} {"geneset":"GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP","description":"Genes up-regulated in CD5 T cells at acute infection with LCMV-Armstrong: effectors at day 15 versus memory at day 30."} {"geneset":"GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_UP","description":"Genes up-regulated in activated CD4 [GeneID=920] T cells expressing: wildtype versus mutant form of FOXP3 [GeneID=50943]."} {"geneset":"GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_DN","description":"Genes down-regulated in activated CD4 [GeneID=920] T cells expressing: wildtype versus mutant form of FOXP3 [GeneID=50943]."} {"geneset":"GSE36826_WT_VS_IL1R_KO_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36826_WT_VS_IL1R_KO_SKIN_DN","description":"Genes down-regulated in skin: wildtype versus IL1R1 [GeneID=3554] knockout."} {"geneset":"GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_UP","description":"Genes up-regulated in skin with IL1R1 [GeneID=3554] knockout: uninfected versus S. aureus infection."} {"geneset":"GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_DN","description":"Genes down-regulated in skin with IL1R1 [GeneID=3554] knockout: uninfected versus S. aureus infection."} {"geneset":"GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_DN","description":"Genes down-regulated in lesional skin biopsies after S. aureus infection: wildtype versus IL1R1 [GeneID=3554]."} {"geneset":"GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP","description":"Genes up-regulated in skin: uninfected versus S. aureus infection."} {"geneset":"GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_DN","description":"Genes down-regulated in skin: uninfected versus S. aureus infection."} {"geneset":"GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP","description":"Genes up-regulated in lesional skin biopsies after S. aureus infection: wildtype versus IL1R1 [GeneID=3554]."} {"geneset":"GSE36826_WT_VS_IL1R_KO_SKIN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE36826_WT_VS_IL1R_KO_SKIN_UP","description":"Genes up-regulated in skin: wildtype versus IL1R1 [GeneID=3554] knockout."} {"geneset":"GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_DN","description":"Genes down-regulated in bone marrow-derived mast cells treated with IL3 [GeneID=3562]: control versus IL33 [GeneID=90865]."} {"geneset":"GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_UP","description":"Genes up-regulated in bone marrow-derived mast cells treated with IL3 [GeneID=3562]: control versus IL33 [GeneID=90865]."} {"geneset":"GSE35435_RESTING_VS_IL4_TREATED_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35435_RESTING_VS_IL4_TREATED_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: resting versus stimulated by IL4 [GeneID=3565]."} {"geneset":"GSE35435_RESTING_VS_IL4_TREATED_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE35435_RESTING_VS_IL4_TREATED_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: resting versus stimulated by IL4 [GeneID=3565]."} {"geneset":"GSE28408_LY6G_POS_VS_NEG_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28408_LY6G_POS_VS_NEG_DC_DN","description":"Genes down-regulated dendritic cells: Ly6G+ versus Ly6G-."} {"geneset":"GSE28408_LY6G_POS_VS_NEG_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE28408_LY6G_POS_VS_NEG_DC_UP","description":"Genes up-regulated dendritic cells: Ly6G+ versus Ly6G-."} {"geneset":"GSE41978_WT_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_WT_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: wildtype versus ID2 and BCL2L11 [GeneID=3398;10018] knockout."} {"geneset":"GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: wildtype versus ID2 [GeneID=3398]."} {"geneset":"GSE41978_WT_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_WT_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: wildtype versus ID2 and BCL2L11 [GeneID=3398;10018] knockout."} {"geneset":"GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T effector cells during infection: KLRG1 high [GeneID=10219] versus KLRG1 low [GeneID=10219]."} {"geneset":"GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T effector cells during infection: KLRG1 high [GeneID=10219] versus KLRG1 low [GeneID=10219]."} {"geneset":"GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: wildtype versus ID2 [GeneID=3398]."} {"geneset":"GSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: wildtype versus BCL2L11 [GeneID=10018] knockout."} {"geneset":"GSE41978_ID2_KO_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_ID2_KO_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 [GeneID=3398] knockout versus ID2 and BCL2L11 [GeneID=3398;10018] knockout."} {"geneset":"GSE41978_ID2_KO_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_ID2_KO_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 [GeneID=3398] knockout versus ID2 and BCL2L11 [GeneID=3398;10018] knockout."} {"geneset":"GSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: wildtype versus BCL2L11 [GeneID=10018] knockout."} {"geneset":"GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 [GeneID=10219] knockout versus BCL2L11 [GeneID=10018] knockout."} {"geneset":"GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 and BCL2L11 [GeneID=3398;10018] versus BCL2L11 [GeneID=10018] knockout."} {"geneset":"GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN","description":"Genes down-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 and BCL2L11 [GeneID=3398;10018] versus BCL2L11 [GeneID=10018] knockout."} {"geneset":"GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP","description":"Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 [GeneID=10219] knockout versus BCL2L11 [GeneID=10018] knockout."} {"geneset":"GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_UP","description":"Genes up-regulated in T reg from: peripheral lymph nodes versus thymic precursors."} {"geneset":"GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_DN","description":"Genes down-regulated in T reg from: peripheral lymph nodes versus thymic precursors."} {"geneset":"GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP","description":"Genes up-regulated in T conv from: peripheral lymph nodes versus thymic precursors."} {"geneset":"GSE42021_TREG_VS_TCONV_PLN_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_VS_TCONV_PLN_UP","description":"Genes up-regulated in cells from peripheral lymph nodes: T reg versus T conv."} {"geneset":"GSE42021_TREG_VS_TCONV_PLN_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_VS_TCONV_PLN_DN","description":"Genes down-regulated in cells from peripheral lymph nodes: T reg versus T conv."} {"geneset":"GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_DN","description":"Genes down-regulated in T reg: peripheral lymph nodes versus thymic CD24 int [GeneID=100133941]."} {"geneset":"GSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_UP","description":"Genes up-regulated in T reg: peripheral lymph nodes versus thymic CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_DN","description":"Genes down-regulated in T reg: peripheral lymph nodes versus thymic CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_UP","description":"Genes up-regulated in thymic T reg: CD24 high [GeneID=100133941] versus CD24 int [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_DN","description":"Genes down-regulated in thymic T reg: CD24 high [GeneID=100133941] versus CD24 int [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_UP","description":"Genes up-regulated in thymic T reg: CD24 high [GeneID=100133941] versus CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_DN","description":"Genes down-regulated in thymic T reg: CD24 high [GeneID=100133941] versus CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_UP","description":"Genes up-regulated in thymic T reg: CD24 int [GeneID=100133941] versus CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_DN","description":"Genes down-regulated in thymic T reg: CD24 int [GeneID=100133941] versus CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_UP","description":"Genes up-regulated in thymic T conv: CD24 high [GeneID=100133941] versus CD24 int [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN","description":"Genes down-regulated in thymic T conv: CD24 high [GeneID=100133941] versus CD24 int [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_UP","description":"Genes up-regulated in thymic T conv: CD24 high [GeneID=100133941] versus CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN","description":"Genes down-regulated in thymic T conv: CD24 high [GeneID=100133941] versus CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_UP","description":"Genes up-regulated in thymic T conv: CD24 int [GeneID=100133941] versus CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_DN","description":"Genes down-regulated in thymic T conv: CD24 int [GeneID=100133941] versus CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_UP","description":"Genes up-regulated in T conv: peripheral lymph nodes versus thymic CD24 high [GeneID=100133941]."} {"geneset":"GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN","description":"Genes down-regulated in T conv: peripheral lymph nodes versus thymic CD24 high [GeneID=100133941]."} {"geneset":"GSE42021_TCONV_PLN_VS_CD24INT_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TCONV_PLN_VS_CD24INT_TCONV_THYMUS_UP","description":"Genes up-regulated in T conv: peripheral lymph nodes versus thymic CD24 int [GeneID=100133941]."} {"geneset":"GSE42021_TCONV_PLN_VS_CD24INT_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TCONV_PLN_VS_CD24INT_TCONV_THYMUS_DN","description":"Genes down-regulated in T conv: peripheral lymph nodes versus thymic CD24 int [GeneID=100133941]."} {"geneset":"GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_UP","description":"Genes up-regulated in T conv: peripheral lymph nodes versus thymic CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_DN","description":"Genes down-regulated in T conv: peripheral lymph nodes versus thymic CD24 low [GeneID=100133941]."} {"geneset":"GSE42021_CD24INT_TREG_VS_CD24INT_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24INT_TREG_VS_CD24INT_TCONV_THYMUS_DN","description":"Genes down-regulated in CD42 int [GeneID=100133941] cells from thymus: T reg versus T conv."} {"geneset":"GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_UP","description":"Genes up-regulated in CD42 low [GeneID=100133941] cells from thymus: T reg versus T conv."} {"geneset":"GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_DN","description":"Genes down-regulated in CD42 low [GeneID=100133941] cells from thymus: T reg versus T conv."} {"geneset":"GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_UP","description":"Genes up-regulated in T reg: peripheral lymph nodes versus thymic CD24 high [GeneID=100133941]."} {"geneset":"GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_DN","description":"Genes down-regulated in T reg: peripheral lymph nodes versus thymic CD24 high [GeneID=100133941]."} {"geneset":"GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP","description":"Genes up-regulated in T reg: peripheral lymph nodes versus thymic CD24 int [GeneID=100133941]."} {"geneset":"GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_UP","description":"Genes up-regulated in CD42 high [GeneID=100133941] cells from thymus: T reg versus T conv."} {"geneset":"GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_DN","description":"Genes down-regulated in CD42 high [GeneID=100133941] cells from thymus: T reg versus T conv."} {"geneset":"GSE42021_CD24INT_TREG_VS_CD24INT_TCONV_THYMUS_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_CD24INT_TREG_VS_CD24INT_TCONV_THYMUS_UP","description":"Genes up-regulated in CD42 int [GeneID=100133941] cells from thymus: T reg versus T conv."} {"geneset":"GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN","description":"Genes down-regulated in T conv from: peripheral lymph nodes versus thymic precursors."} {"geneset":"GSE27434_WT_VS_DNMT1_KO_TREG_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27434_WT_VS_DNMT1_KO_TREG_UP","description":"Genes up-regulated in T reg: wildtype versus DNMT1 [GeneID=1786] knockout."} {"geneset":"GSE27434_WT_VS_DNMT1_KO_TREG_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE27434_WT_VS_DNMT1_KO_TREG_DN","description":"Genes down-regulated in T reg: wildtype versus DNMT1 [GeneID=1786] knockout."} {"geneset":"GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_UP","description":"Genes up-regulated in peripheral blood monocytes (PBMC): control versus IL10 [GeneID=3586]."} {"geneset":"GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_DN","description":"Genes down-regulated in peripheral blood monocytes (PBMC): control versus IL10 [GeneID=3586]."} {"geneset":"GSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th0: control versus NaCl treatment."} {"geneset":"GSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: control versus NaCl treatment."} {"geneset":"GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper Th17 cells: wildtype versus SGK1 [GeneID-6446] knockout."} {"geneset":"GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper Th17 cells: wildtype versus SGK1 [GeneID-6446] knockout."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (42h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (42h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (52h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (1h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (1h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (4h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (4h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (10h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (10h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (20h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (20h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (30h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (30h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_1H_VS_60H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_60H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 60h."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (52h): Th0 versus Th17 treated with TGFB1, IL6 [GeneID=7040;3569] and IL-23."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (52h): Th0 versus Th17 treated with TGFB1, IL6 [GeneID=7040;3569] and IL-23."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (52h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (60h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (60h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]."} {"geneset":"GSE43955_1H_VS_10H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_10H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 10h."} {"geneset":"GSE43955_1H_VS_10H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_10H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 10h."} {"geneset":"GSE43955_1H_VS_20H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_20H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 20h."} {"geneset":"GSE43955_1H_VS_20H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_20H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 20h."} {"geneset":"GSE43955_1H_VS_42H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_42H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 42h."} {"geneset":"GSE43955_1H_VS_42H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_42H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 42h."} {"geneset":"GSE43955_1H_VS_60H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_60H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 60h."} {"geneset":"GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 (52h): TGFB1 and IL6 [GeneID=7040;3569] versus TGFB1, IL6 [GeneID=7040;3569] and IL-23."} {"geneset":"GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 (52h): TGFB1 and IL6 [GeneID=7040;3569] versus TGFB1, IL6 [GeneID=7040;3569] and IL-23."} {"geneset":"GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 (60h): TGFB1 and IL6 [GeneID=7040;3569] versus TGFB1, IL6 [GeneID=7040;3569] and IL-23."} {"geneset":"GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 (60h): TGFB1 and IL6 [GeneID=7040;3569] versus TGFB1, IL6 [GeneID=7040;3569] and IL-23."} {"geneset":"GSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 10h."} {"geneset":"GSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 10h."} {"geneset":"GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 20h."} {"geneset":"GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 20h."} {"geneset":"GSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 42h."} {"geneset":"GSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 42h."} {"geneset":"GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 60h."} {"geneset":"GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 60h."} {"geneset":"GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 10h versus 60h."} {"geneset":"GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 10h versus 60h."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells (60h): Th0 versus Th17 treated with TGFB1, IL6 [GeneID=7040;3569] and IL-23."} {"geneset":"GSE43955_10H_VS_30H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_10H_VS_30H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th0: 10h versus 30h."} {"geneset":"GSE43955_10H_VS_30H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_10H_VS_30H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 10h versus 30h."} {"geneset":"GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells (60h): Th0 versus Th17 treated with TGFB1, IL6 [GeneID=7040;3569] and IL-23."} {"geneset":"GSE43955_10H_VS_60H_ACT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_10H_VS_60H_ACT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 10h versus 60h."} {"geneset":"GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 10h versus 30h."} {"geneset":"GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN","description":"Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 10h versus 30h."} {"geneset":"GSE43955_10H_VS_60H_ACT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43955_10H_VS_60H_ACT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T helper cells Th0: 10h versus 60h."} {"geneset":"GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_UP","description":"Genes up-regulated in immature dendritic cells: untreated versus IL27 [GeneID=246778]."} {"geneset":"GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN","description":"Genes down-regulated in immature dendritic cells: untreated versus IL27 [GeneID=246778]."} {"geneset":"GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN","description":"Genes down-regulated in macrophage differentiated by: CSF1 [GeneID=1435] versus CSF1 [GeneID=1435] and IL27 [GeneID=246778]."} {"geneset":"GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_UP","description":"Genes up-regulated in macrophage differentiated by: CSF1 [GeneID=1435] versus CSF1 [GeneID=1435] and IL27 [GeneID=246778]."} {"geneset":"GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] Th1 cells: wildtype versus EGR2 [GeneID=1959] knockout."} {"geneset":"GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] Th1 cells: wildtype versus EGR2 [GeneID=1959] knockout."} {"geneset":"GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP","description":"Genes up-regulated in anergic CD4 [GeneID=920] Th1 cells: wildtype versus EGR2 [GeneID=1959] knockout."} {"geneset":"GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_DN","description":"Genes down-regulated in anergic CD4 [GeneID=920] Th1 cells: wildtype versus EGR2 [GeneID=1959] knockout."} {"geneset":"GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] Th1 cells: control versus anergic."} {"geneset":"GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] Th1 cells: control versus anergic."} {"geneset":"GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_UP","description":"Genes up-regulated in CD4 [GeneID=920] Th1 cells with EGR2 [GeneID=1959] knockout: control versus anergic."} {"geneset":"GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_DN","description":"Genes down-regulated in CD4 [GeneID=920] Th1 cells with EGR2 [GeneID=1959] knockout: control versus anergic."} {"geneset":"GSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus Th1 memory."} {"geneset":"GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus Ly6c low CXCR5- effector during acute infection of LCMV."} {"geneset":"GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus Ly6c low CXCR5- effector during acute infection of LCMV."} {"geneset":"GSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus Th1 memory."} {"geneset":"GSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA cells: naü¾™¦”¼ve versus during acute infection of LCMV."} {"geneset":"GSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA cells: naü¾™¦”¼ve versus during acute infection of LCMV."} {"geneset":"GSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus effector during acute infection of LCMV."} {"geneset":"GSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus effector during acute infection of LCMV."} {"geneset":"GSE43863_NAIVE_VS_LY6C_INT_CXCR5POS_CD4_EFF_TCELL_D6_LCMV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_LY6C_INT_CXCR5POS_CD4_EFF_TCELL_D6_LCMV_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus Ly6c+ CXCR5+ [GeneID=643] effector during acute infection of LCMV."} {"geneset":"GSE43863_NAIVE_VS_LY6C_INT_CXCR5POS_CD4_EFF_TCELL_D6_LCMV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_LY6C_INT_CXCR5POS_CD4_EFF_TCELL_D6_LCMV_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus Ly6c+ CXCR5+ [GeneID=643] effector during acute infection of LCMV."} {"geneset":"GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN","description":"Genes down-regulated in Ly6c int CXCR5+ CD4 [GeneID=643;920] T cells: effector during acute infection of LCMV versus memory."} {"geneset":"GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus follicular helper (Tfh)."} {"geneset":"GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus follicular helper (Tfh)."} {"geneset":"GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus Ly6c int CXCR5+ [GeneID=643]."} {"geneset":"GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus memory follicular helper (Tfh)."} {"geneset":"GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus memory follicular helper (Tfh)."} {"geneset":"GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus Ly6c int CXCR5+ [GeneID=643] memory."} {"geneset":"GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naü¾™¦”¼ve versus Ly6c int CXCR5+ [GeneID=643] memory."} {"geneset":"GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_UP","description":"Genes up-regulated in Th1 CD4 [GeneID=920] SMARTA T cells: effector during acute infection of LCMV versus memory."} {"geneset":"GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_DN","description":"Genes down-regulated in Th1 CD4 [GeneID=920] SMARTA T cells: effector during acute infection of LCMV versus memory."} {"geneset":"GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_UP","description":"Genes up-regulated in follicular helper CD4 [GeneID=920] SMARTA T cells (Tfh): effector during acute infection of LCMV versus memory."} {"geneset":"GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_DN","description":"Genes down-regulated in follicular helper CD4 [GeneID=920] SMARTA T cells (Tfh): effector during acute infection of LCMV versus memory."} {"geneset":"GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_UP","description":"Genes up-regulated in Ly6c int CXCR5+ CD4 [GeneID=643;920] T cells: effector during acute infection of LCMV versus memory."} {"geneset":"GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: follicular helper (Tfh) versus Ly6c int CXCR5+ [GeneID=643]."} {"geneset":"GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: follicular helper (Tfh) versus Ly6c low CXCR5- [GeneID=643]."} {"geneset":"GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: follicular helper (Tfh) versus Ly6c low CXCR5- [GeneID=643]."} {"geneset":"GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Ly6c int CXCR5+ [GeneID=643] versus Ly6c low CXCR5- [GeneID=643]."} {"geneset":"GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Ly6c int CXCR5+ [GeneID=643] versus Ly6c low CXCR5- [GeneID=643]."} {"geneset":"GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus Ly6c int CXCR5+ [GeneID=643]."} {"geneset":"GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA memory T cells: follicular helper (Tfh) versus Ly6c int CXCR5+ [GeneID=643]."} {"geneset":"GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA memory T cells: follicular helper (Tfh) versus Ly6c int CXCR5+ [GeneID=643]."} {"geneset":"GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus follicular helper (Tfh)."} {"geneset":"GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus follicular helper (Tfh)."} {"geneset":"GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus Ly6c int CXCR5+ [GeneID=643]."} {"geneset":"GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus Ly6c int CXCR5+ [GeneID=643]."} {"geneset":"GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus Ly6c low CXCR5- [GeneID=643]."} {"geneset":"GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus Ly6c low CXCR5- [GeneID=643]."} {"geneset":"GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: follicular helper (Tfh) versus Ly6c int CXCR5+ [GeneID=643]."} {"geneset":"GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_UP","description":"Genes up-regulated in MME+ [GeneID=4311] germinal center B lymphocytes: control versus over-expressing viral (EBV) gene LMP2A."} {"geneset":"GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_DN","description":"Genes down-regulated in MME+ [GeneID=4311] germinal center B lymphocytes: control versus over-expressing viral (EBV) gene LMP2A."} {"geneset":"GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_UP","description":"Genes up-regulated in CD8 T cells: resting versus activated."} {"geneset":"GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_UP","description":"Genes up-regulated in CD8 T cells with MIR155 [GeneID=406947] knockout: resting versus activated."} {"geneset":"GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_DN","description":"Genes down-regulated in CD8 T cells with MIR155 [GeneID=406947] knockout: resting versus activated."} {"geneset":"GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP","description":"Genes up-regulated in resting CD8 T cells: wildtype versus MIR155 [GeneID=406947] knockout."} {"geneset":"GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_DN","description":"Genes down-regulated in CD8 T cells: resting versus activated."} {"geneset":"GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_UP","description":"Genes up-regulated in activated CD8 T cells: wildtype versus MIR155 [GeneID=406947] knockout."} {"geneset":"GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_DN","description":"Genes down-regulated in activated CD8 T cells: wildtype versus MIR155 [GeneID=406947] knockout."} {"geneset":"GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_DN","description":"Genes down-regulated in resting CD8 T cells: wildtype versus MIR155 [GeneID=406947] knockout."} {"geneset":"GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP","description":"Genes up-regulated in B lymphocytes: memory versus plasmablasts."} {"geneset":"GSE42724_B1_BCELL_VS_PLASMABLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_B1_BCELL_VS_PLASMABLAST_UP","description":"Genes up-regulated in B lymphocytes: B1 versus plasmablasts."} {"geneset":"GSE42724_B1_BCELL_VS_PLASMABLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_B1_BCELL_VS_PLASMABLAST_DN","description":"Genes down-regulated in B lymphocytes: B1 versus plasmablasts."} {"geneset":"GSE42724_NAIVE_VS_B1_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_NAIVE_VS_B1_BCELL_UP","description":"Genes up-regulated in B lymphocytes: naü¾™¦”¼ve versus B1."} {"geneset":"GSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN","description":"Genes down-regulated in B lymphocytes: memory versus plasmablasts."} {"geneset":"GSE42724_NAIVE_VS_MEMORY_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_NAIVE_VS_MEMORY_BCELL_UP","description":"Genes up-regulated in B lymphocytes: naü¾™¦”¼ve versus memory."} {"geneset":"GSE42724_NAIVE_VS_MEMORY_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_NAIVE_VS_MEMORY_BCELL_DN","description":"Genes down-regulated in B lymphocytes: naü¾™¦”¼ve versus memory."} {"geneset":"GSE42724_MEMORY_VS_B1_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_MEMORY_VS_B1_BCELL_UP","description":"Genes up-regulated in B lymphocytes: memory versus B1."} {"geneset":"GSE42724_NAIVE_VS_B1_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_NAIVE_VS_B1_BCELL_DN","description":"Genes down-regulated in B lymphocytes: naü¾™¦”¼ve versus B1."} {"geneset":"GSE42724_NAIVE_BCELL_VS_PLASMABLAST_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_NAIVE_BCELL_VS_PLASMABLAST_UP","description":"Genes up-regulated in B lymphocytes: naü¾™¦”¼ve versus plasmablasts."} {"geneset":"GSE42724_NAIVE_BCELL_VS_PLASMABLAST_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_NAIVE_BCELL_VS_PLASMABLAST_DN","description":"Genes down-regulated in B lymphocytes: naü¾™¦”¼ve versus plasmablasts."} {"geneset":"GSE42724_MEMORY_VS_B1_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42724_MEMORY_VS_B1_BCELL_DN","description":"Genes down-regulated in B lymphocytes: memory versus B1."} {"geneset":"GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_UP","description":"Genes up-regulated in macrophages: untreated versus TGFB2 [GeneID=7042]."} {"geneset":"GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_DN","description":"Genes down-regulated in macrophages: untreated versus TGFB2 [GeneID=7042]."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_UP","description":"Genes up-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4-KO."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_DN","description":"Genes down-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4-KO."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_UP","description":"Genes up-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4-KO."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_DN","description":"Genes down-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4-KO."} {"geneset":"GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype."} {"geneset":"GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype."} {"geneset":"GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B 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{"geneset":"GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4_KO_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4-KO."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_UP","description":"Genes up-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN","description":"Genes down-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_UP","description":"Genes up-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN","description":"Genes down-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP","description":"Genes up-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN","description":"Genes down-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP","description":"Genes up-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN","description":"Genes down-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate."} {"geneset":"GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high."} {"geneset":"GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high."} {"geneset":"GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate."} {"geneset":"GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate."} {"geneset":"GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate."} {"geneset":"GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate."} {"geneset":"GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate."} {"geneset":"GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate."} {"geneset":"GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype."} {"geneset":"GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype."} {"geneset":"GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype."} {"geneset":"GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype."} {"geneset":"GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype."} {"geneset":"GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype."} {"geneset":"GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype."} {"geneset":"GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype."} {"geneset":"GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_UP","description":"Genes up-regulated in at day 0 B cell IRF4-KO versus at day 0 B cell wildtype."} {"geneset":"GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_DN","description":"Genes down-regulated in at day 0 B cell IRF4-KO versus at day 0 B cell wildtype."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP","description":"Genes up-regulated in at day 0 B cell wildtype versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN","description":"Genes down-regulated in at day 0 B cell wildtype versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP","description":"Genes up-regulated in at day 0 B cell wildtype versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype."} {"geneset":"GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN","description":"Genes down-regulated in at day 0 B cell wildtype versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype."} {"geneset":"GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_UP","description":"Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype."} {"geneset":"GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_DN","description":"Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype."} {"geneset":"GSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_UP","description":"Genes up-regulated during acute viral infection in KLRG1 low [GeneID=10219] CD8 T cells: wildtype versus FOXO1 [GeneID=2308] knockout."} {"geneset":"GSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_DN","description":"Genes down-regulated during acute viral infection in KLRG1 low [GeneID=10219] CD8 T cells: wildtype versus FOXO1 [GeneID=2308] knockout."} {"geneset":"GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: NRAS [GeneID=4893] knockout versus wildtype."} {"geneset":"GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: NRAS [GeneID=4893] knockout versus wildtype."} {"geneset":"GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_UP","description":"Genes up-regulated in activated CD4 [GeneID=920] T cells: NRAS [GeneID=4893] knockout versus wildtype."} {"geneset":"GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN","description":"Genes down-regulated in activated CD4 [GeneID=920] T cells: NRAS [GeneID=4893] knockout versus wildtype."} {"geneset":"GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells with NRAS [GeneID=4893] knockout: unstimulated versus activated."} {"geneset":"GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells with NRAS [GeneID=4893] knockout: unstimulated versus activated."} {"geneset":"GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_UP","description":"Genes up-regulated in CD4 [GeneID=920] T cells: unstimulated versus activated."} {"geneset":"GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_DN","description":"Genes down-regulated in CD4 [GeneID=920] T cells: unstimulated versus activated."} {"geneset":"GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP","description":"Genes up-regulated in colonic lamina propria cells sorted by CXCR6 [GeneID=10663]: high versus low."} {"geneset":"GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_DN","description":"Genes down-regulated in colonic lamina propria cells sorted by CXCR6 [GeneID=10663]: high versus low."} {"geneset":"GSE45837_WT_VS_GFI1_KO_PDC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45837_WT_VS_GFI1_KO_PDC_UP","description":"Genes up-regulated in plasmacytoid dendritic cells: wildtype versus GFI1 [GeneID=2672] knockout."} {"geneset":"GSE45837_WT_VS_GFI1_KO_PDC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45837_WT_VS_GFI1_KO_PDC_DN","description":"Genes down-regulated in plasmacytoid dendritic cells: wildtype versus GFI1 [GeneID=2672] knockout."} {"geneset":"GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP","description":"Genes up-regulated in dendritic cells: untreated versus 24h after infection of Leishmania major."} {"geneset":"GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_DN","description":"Genes down-regulated in dendritic cells: untreated versus 24h after infection of Leishmania major."} {"geneset":"GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_UP","description":"Genes up-regulated in dendritic cells infected by Leishmania major: 2h versus 24h."} {"geneset":"GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_UP","description":"Genes up-regulated in dendritic cells: untreated versus 2h after infection of Leishmania major."} {"geneset":"GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_DN","description":"Genes down-regulated in dendritic cells: untreated versus 2h after infection of Leishmania major."} {"geneset":"GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP","description":"Genes up-regulated in dendritic cells: untreated versus 4h after infection of Leishmania major."} {"geneset":"GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_DN","description":"Genes down-regulated in dendritic cells: untreated versus 4h after infection of Leishmania major."} {"geneset":"GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_UP","description":"Genes up-regulated in dendritic cells: untreated versus 8h after infection of Leishmania major."} {"geneset":"GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_DN","description":"Genes down-regulated in dendritic cells: untreated versus 8h after infection of Leishmania major."} {"geneset":"GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_DN","description":"Genes down-regulated in dendritic cells infected by Leishmania major: 2h versus 24h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN","description":"Genes down-regulated in B lymphocytes: untreated versus anti-IgM for 1h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_UP","description":"Genes up-regulated in B lymphocytes: untreated versus anti-IgM for 3h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN","description":"Genes down-regulated in B lymphocytes: untreated versus anti-IgM for 3h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_UP","description":"Genes up-regulated in B lymphocytes: untreated versus anti-IgM for 1h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_UP","description":"Genes up-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 24h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_DN","description":"Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 24h."} {"geneset":"GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_UP","description":"Genes up-regulated in B lymphocytes: wildtype versus MAP3K7 [GeneID=6885]."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_UP","description":"Genes up-regulated in B lymphocytes: untreated versus anti-IgM for 6h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_DN","description":"Genes down-regulated in B lymphocytes: untreated versus anti-IgM for 6h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_UP","description":"Genes up-regulated in B lymphocytes: untreated versus anti-IgM for 24h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN","description":"Genes down-regulated in B lymphocytes: untreated versus anti-IgM for 24h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_1H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_1H_UP","description":"Genes up-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 1h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_1H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_1H_DN","description":"Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 1h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_UP","description":"Genes up-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 3h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_DN","description":"Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 3h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_6H_UP","description":"Genes up-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 6h."} {"geneset":"GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_6H_DN","description":"Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 6h."} {"geneset":"GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_UP","description":"Genes up-regulated in B lymphocytes treated by anti IgM for 1h: wildtype versus MAP3K7 [GeneID=6885] knockout."} {"geneset":"GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_DN","description":"Genes down-regulated in B lymphocytes treated by anti IgM for 1h: wildtype versus MAP3K7 [GeneID=6885] knockout."} {"geneset":"GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_UP","description":"Genes up-regulated in B lymphocytes treated by anti IgM for 3h: wildtype versus MAP3K7 [GeneID=6885] knockout."} {"geneset":"GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_DN","description":"Genes down-regulated in B lymphocytes: wildtype versus MAP3K7 [GeneID=6885]."} {"geneset":"GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_UP","description":"Genes up-regulated in B lymphocytes treated by anti IgM for 6h: wildtype versus MAP3K7 [GeneID=6885] knockout."} {"geneset":"GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_DN","description":"Genes down-regulated in B lymphocytes treated by anti IgM for 6h: wildtype versus MAP3K7 [GeneID=6885] knockout."} {"geneset":"GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_UP","description":"Genes up-regulated in B lymphocytes treated by anti IgM for 24h: wildtype versus MAP3K7 [GeneID=6885] knockout."} {"geneset":"GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_DN","description":"Genes down-regulated in B lymphocytes treated by anti IgM for 3h: wildtype versus MAP3K7 [GeneID=6885] knockout."} {"geneset":"GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_DN","description":"Genes down-regulated in B lymphocytes treated by anti IgM for 24h: wildtype versus MAP3K7 [GeneID=6885] knockout."} {"geneset":"GSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_UP","description":"Genes up-regulated in tumor-infiltrating CD8 T cells: BTLA+ [GeneID=151888] versus BTLA- [GeneID=151888]."} {"geneset":"GSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_DN","description":"Genes down-regulated in tumor-infiltrating CD8 T cells: BTLA+ [GeneID=151888] versus BTLA- [GeneID=151888]."} {"geneset":"GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_UP","description":"Genes up-regulated during primary acute viral infection: NK cells versus ITGAM+ [GeneID=3684] dendritic cells."} {"geneset":"GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_DN","description":"Genes down-regulated during primary acute viral infection: NK cells versus ITGAM+ [GeneID=3684] dendritic cells."} {"geneset":"GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_UP","description":"Genes up-regulated during primary acute viral infection: NK cells versus B lymphocytes."} {"geneset":"GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_DN","description":"Genes down-regulated during primary acute viral infection: NK cells versus B lymphocytes."} {"geneset":"GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_UP","description":"Genes up-regulated during primary acute viral infection: NK vells versus CD8 T cells."} {"geneset":"GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_DN","description":"Genes down-regulated during primary acute viral infection: NK vells versus CD8 T cells."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_CD8A_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_CD8A_DC_UP","description":"Genes up-regulated in CD8A [GeneID=925] dendritic cells: wildtype versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN","description":"Genes down-regulated in CD8A [GeneID=925] 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infection."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN","description":"Genes down-regulated in CD8A [GeneID=925] dendritic cells: control versus primary acute viral infection."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP","description":"Genes up-regulated in CD8A [GeneID=925] dendritic cells with IFNAR1 [GeneID=3454] knockout: control versus primary acute viral infection."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_DN","description":"Genes down-regulated in CD8A [GeneID=925] dendritic cells with IFNAR1 [GeneID=3454] knockout: control versus primary acute viral infection."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_CD11B_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_CD11B_DC_UP","description":"Genes up-regulated in ITGAM+ [GeneID=3684] dendritic cells: wildtype versus IFNAR1 [GeneID=3454]."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_CD11B_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_CD11B_DC_DN","description":"Genes down-regulated in ITGAM+ [GeneID=3684] dendritic cells: wildtype versus IFNAR1 [GeneID=3454]."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_CD11B_DC_MCMV_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_CD11B_DC_MCMV_INFECTION_UP","description":"Genes up-regulated during primary acute viral infection in ITGAM+ [GeneID=3684] dendritic cells: wildtype versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_CD11B_DC_MCMV_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_CD11B_DC_MCMV_INFECTION_DN","description":"Genes down-regulated during primary acute viral infection in ITGAM+ [GeneID=3684] dendritic cells: wildtype versus IFNAR1 [GeneID=3454] knockout."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_UP","description":"Genes up-regulated in ITGAM+ [GeneID=3684] dendritic cells: control versus primary acute viral infection."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_DN","description":"Genes down-regulated in ITGAM+ [GeneID=3684] dendritic cells: control versus primary acute viral infection."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_UP","description":"Genes up-regulated in ITGAM+ [GeneID=3684] dendritic cells with IFNAR1 [GeneID=3454] knockout: control versus primary acute viral infection."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN","description":"Genes down-regulated in ITGAM+ [GeneID=3684] dendritic cells with IFNAR1 [GeneID=3454] knockout: control versus primary acute viral infection."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_BCELL_UP","description":"Genes up-regulated in B lymphocytes: control versus primary acute viral infection."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_BCELL_DN","description":"Genes down-regulated in B lymphocytes: control versus primary acute viral infection."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_UP","description":"Genes up-regulated in CD8 T cells: control versus primary acute viral infection."} {"geneset":"GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_DN","description":"Genes down-regulated in CD8 T cells: control versus primary acute viral infection."} {"geneset":"GSE45365_BCELL_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_BCELL_VS_CD8_TCELL_UP","description":"Genes up-regulated in B lymphocytes versus CD8 T cells."} {"geneset":"GSE45365_BCELL_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_BCELL_VS_CD8_TCELL_DN","description":"Genes down-regulated in B lymphocytes versus CD8 T cells."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_UP","description":"Genes up-regulated during primary acute viral infection: B lymphocytes versus CD8 T cells."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_DN","description":"Genes down-regulated during primary acute viral infection: B lymphocytes versus CD8 T cells."} {"geneset":"GSE45365_CD8A_DC_VS_CD11B_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_CD8A_DC_VS_CD11B_DC_UP","description":"Genes up-regulated in dendritic cells: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]."} {"geneset":"GSE45365_CD8A_DC_VS_CD11B_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_CD8A_DC_VS_CD11B_DC_DN","description":"Genes down-regulated in dendritic cells: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]."} {"geneset":"GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_UP","description":"Genes up-regulated in dendritic cells with IFNAR1 [GeneID=3454] knockout: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]."} {"geneset":"GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_DN","description":"Genes down-regulated in dendritic cells with IFNAR1 [GeneID=3454] knockout: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]."} {"geneset":"GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_MCMV_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_MCMV_INFECTION_UP","description":"Genes up-regulated during primary acute viral infection in dendritic cells: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]."} {"geneset":"GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_MCMV_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_MCMV_INFECTION_DN","description":"Genes down-regulated during primary acute viral infection in dendritic cells: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8_TCELL_IFNAR_KO_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8_TCELL_IFNAR_KO_UP","description":"Genes up-regulated during primary acute viral infection in dendritic cells with IFNAR1 [GeneID=3454] knockout: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]."} {"geneset":"GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8_TCELL_IFNAR_KO_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8_TCELL_IFNAR_KO_DN","description":"Genes down-regulated during primary acute viral infection in dendritic cells with IFNAR1 [GeneID=3454] knockout: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]."} {"geneset":"GSE45365_NK_CELL_VS_CD8_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD8_TCELL_DN","description":"Genes down-regulated in NK cells versus CD8 T cells."} {"geneset":"GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_UP","description":"Genes up-regulated during primary acute viral infection: NK cells versus CD8A [GeneID=625] dendritic cells."} {"geneset":"GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_DN","description":"Genes down-regulated during primary acute viral infection: NK cells versus CD8A [GeneID=625] dendritic cells."} {"geneset":"GSE37336_LY6C_POS_VS_NEG_NAIVE_CD4_TCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37336_LY6C_POS_VS_NEG_NAIVE_CD4_TCELL_DN","description":"Genes down-regulated naü¾™¦”¼ve CD4 [GeneID=920] T cells: Ly6c+ versus Ly6c-."} {"geneset":"GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: control versus glioblastoma conditioned."} {"geneset":"GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: control versus glioblastoma conditioned."} {"geneset":"GSE37336_LY6C_POS_VS_NEG_NAIVE_CD4_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE37336_LY6C_POS_VS_NEG_NAIVE_CD4_TCELL_UP","description":"Genes up-regulated naü¾™¦”¼ve CD4 [GeneID=920] T cells: Ly6c+ versus Ly6c-."} {"geneset":"GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_DN","description":"Genes down-regulated in tumor associated macrophages conditioned by: glioblastoma versus colorectal adenocarcinoma."} {"geneset":"GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: control versus tumor associated."} {"geneset":"GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: control versus tumor associated."} {"geneset":"GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_UP","description":"Genes up-regulated in tumor associated macrophages conditioned by: glioblastoma versus colorectal adenocarcinoma."} {"geneset":"GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_DN","description":"Genes down-regulated in NK cells: control versus acute primary viral infection."} {"geneset":"GSE45365_NK_CELL_VS_BCELL_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_BCELL_DN","description":"Genes down-regulated in NK cells versus B lymphocytes."} {"geneset":"GSE45365_NK_CELL_VS_CD8_TCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD8_TCELL_UP","description":"Genes up-regulated in NK cells versus CD8 T cells."} {"geneset":"GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_UP","description":"Genes up-regulated in NK cells: control versus acute primary viral infection."} {"geneset":"GSE45365_NK_CELL_VS_CD11B_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD11B_DC_DN","description":"Genes down-regulated in NK cells versus ITGAM+ [GeneID=3684] dendritic cells."} {"geneset":"GSE45365_NK_CELL_VS_CD8A_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD8A_DC_UP","description":"Genes up-regulated in NK cells versus CD8A [GeneID=925] T cells."} {"geneset":"GSE45365_NK_CELL_VS_CD8A_DC_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD8A_DC_DN","description":"Genes down-regulated in NK cells versus CD8A [GeneID=925] T cells."} {"geneset":"GSE45365_NK_CELL_VS_CD11B_DC_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_CD11B_DC_UP","description":"Genes up-regulated in NK cells versus ITGAM+ [GeneID=3684] dendritic cells."} {"geneset":"GSE45365_NK_CELL_VS_BCELL_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE45365_NK_CELL_VS_BCELL_UP","description":"Genes up-regulated in NK cells versus B lymphocytes."} {"geneset":"GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP","description":"Genes up-regulated in macrophages: control versus colorectal adenocarcinoma conditioned."} {"geneset":"GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_DN","url":"http://www.broadinstitute.org/gsea/msigdb/cards/GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_DN","description":"Genes down-regulated in macrophages: control versus colorectal adenocarcinoma conditioned."}