Changes in version 1.35.2 (2018-06-28)                 

    o   Updating! Extend aFold to paired samples

                 Changes in version 1.32.2 (2017-12-18)                 

    o   Updating! Refine qtotal (R funtion: qtotalNormalized)

                 Changes in version 1.30.1 (2017-07-18)                 

    o   Updating! Adapt aFold model for complex design with linear model (R funtion: ABSSeqlm)

    o   Updating! Introduce a new approach for normalization as qtotal (R funtion: qtotalNormalized)

    o   aFold now moderates fold changes upon overall dispersion and gene-specific dispersion

                 Changes in version 1.11.0 (2017-02-14)                 

    o   Updating! Adding new method: aFold to call DE via fold-change

                 Changes in version 1.6.0 (2016-02-29)                  

    o   Updating! Enable the paired comparison by seting up 'paired' parameter in 'ABSDataSet' object

                 Changes in version 1.5.1 (2015-08-24)                  

    o   This is the second version of ABSSeq.
	o Use NB distribution insead of GP to model the counts difference between conditions
	o Introduce an efficient outlier detection method: moderated MAD
	o Introduce penalty for dispersion estimation
	o Provide moderation of log2 fold-change at expression level and gene-specific dispersion